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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HIC2

Z-value: 0.59

Motif logo

Transcription factors associated with HIC2

Gene Symbol Gene ID Gene Info
ENSG00000169635.5 HIC ZBTB transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIC2hg19_v2_chr22_+_21771656_21771693-0.045.1e-01Click!

Activity profile of HIC2 motif

Sorted Z-values of HIC2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_94856951 23.68 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94856987 22.18 ENST00000449399.3
ENST00000404814.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94857004 16.41 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_106092403 16.30 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr3_+_10206545 16.15 ENST00000256458.4
interleukin-1 receptor-associated kinase 2
chr14_-_106209368 14.88 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_-_27620603 14.67 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr11_-_5248294 14.51 ENST00000335295.4
hemoglobin, beta
chr5_-_172198190 14.39 ENST00000239223.3
dual specificity phosphatase 1
chr9_+_124088860 13.95 ENST00000373806.1
gelsolin
chr22_+_33197683 13.88 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr7_+_30960915 13.81 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr12_-_15038779 13.78 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr12_-_7245125 13.69 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr6_+_31865552 11.69 ENST00000469372.1
ENST00000497706.1
complement component 2
chr9_+_124030338 11.45 ENST00000449773.1
ENST00000432226.1
ENST00000436847.1
ENST00000394353.2
ENST00000449733.1
ENST00000412819.1
ENST00000341272.2
ENST00000373808.2
gelsolin
chr1_-_153363452 10.89 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chr18_+_71815743 10.57 ENST00000169551.6
ENST00000580087.1
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr1_-_120311517 10.36 ENST00000369406.3
ENST00000544913.2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chrX_-_17878827 10.35 ENST00000360011.1
retinoic acid induced 2
chr1_+_10270863 10.28 ENST00000377093.4
ENST00000263934.6
kinesin family member 1B
chr19_+_33182823 10.14 ENST00000397061.3
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_-_2162468 9.62 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr14_+_101193246 9.50 ENST00000331224.6
delta-like 1 homolog (Drosophila)
chr17_+_1674982 9.42 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_+_101193164 9.21 ENST00000341267.4
delta-like 1 homolog (Drosophila)
chr9_+_139871948 8.96 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr22_-_37415475 8.95 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
thiosulfate sulfurtransferase (rhodanese)
chr3_+_32726774 8.92 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr14_-_106054659 8.92 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr10_+_124221036 8.84 ENST00000368984.3
HtrA serine peptidase 1
chr17_-_18218237 8.76 ENST00000542570.1
topoisomerase (DNA) III alpha
chr10_-_71169031 8.70 ENST00000373307.1
tachykinin receptor 2
chr3_-_138763734 8.63 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr11_+_46722368 8.55 ENST00000311764.2
zinc finger protein 408
chr1_+_159175201 8.53 ENST00000368121.2
Duffy blood group, atypical chemokine receptor
chr3_+_52529346 8.34 ENST00000321725.6
stabilin 1
chr11_-_2162162 8.32 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr14_+_73704201 8.26 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
papilin, proteoglycan-like sulfated glycoprotein
chr11_+_61717279 8.20 ENST00000378043.4
bestrophin 1
chrX_-_43741594 8.02 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chr11_+_71927807 7.93 ENST00000298223.6
ENST00000454954.2
ENST00000541003.1
ENST00000539412.1
ENST00000536778.1
ENST00000535625.1
ENST00000321324.7
folate receptor 2 (fetal)
chr2_+_26915584 7.90 ENST00000302909.3
potassium channel, subfamily K, member 3
chr19_-_17488143 7.84 ENST00000599426.1
ENST00000252590.4
plasmalemma vesicle associated protein
chr11_+_61717336 7.81 ENST00000378042.3
bestrophin 1
chr22_+_23243156 7.81 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr5_-_41261540 7.74 ENST00000263413.3
complement component 6
chr5_-_159739532 7.73 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
cyclin J-like
chrX_+_70435044 7.67 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
gap junction protein, beta 1, 32kDa
chr16_+_56642489 7.55 ENST00000561491.1
metallothionein 2A
chr10_-_95360983 7.54 ENST00000371464.3
retinol binding protein 4, plasma
chr11_+_17756279 7.52 ENST00000265969.6
potassium voltage-gated channel, Shaw-related subfamily, member 1
chr11_+_1889880 7.47 ENST00000405957.2
lymphocyte-specific protein 1
chr12_-_56882136 7.36 ENST00000311966.4
glutaminase 2 (liver, mitochondrial)
chr17_+_38083977 7.26 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr15_+_75118888 7.13 ENST00000395018.4
complexin 3
chr11_-_111783595 7.09 ENST00000528628.1
crystallin, alpha B
chr11_-_2170786 6.82 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chr19_+_45418067 6.77 ENST00000589078.1
ENST00000586638.1
apolipoprotein C-I
chr4_+_156588806 6.70 ENST00000513574.1
guanylate cyclase 1, soluble, alpha 3
chr3_+_148457585 6.69 ENST00000402260.1
angiotensin II receptor, type 1
chrX_+_152224766 6.64 ENST00000370265.4
ENST00000447306.1
paraneoplastic Ma antigen 3
chr19_+_859425 6.57 ENST00000327726.6
complement factor D (adipsin)
chr12_+_53443963 6.54 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chrX_+_68048803 6.51 ENST00000204961.4
ephrin-B1
chr17_-_18218270 6.51 ENST00000321105.5
topoisomerase (DNA) III alpha
chr22_-_18923655 6.47 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr8_+_21915368 6.46 ENST00000265800.5
ENST00000517418.1
dematin actin binding protein
chr19_+_45417504 6.44 ENST00000588750.1
ENST00000588802.1
apolipoprotein C-I
chr13_+_96204961 6.43 ENST00000299339.2
claudin 10
chr2_-_24583314 6.42 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
intersectin 2
chr4_+_156588350 6.40 ENST00000296518.7
guanylate cyclase 1, soluble, alpha 3
chr3_+_169490606 6.35 ENST00000349841.5
myoneurin
chr11_-_66084508 6.34 ENST00000311330.3
CD248 molecule, endosialin
chr2_+_105471969 6.33 ENST00000361360.2
POU class 3 homeobox 3
chr22_+_30792980 6.28 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14-like 2 (S. cerevisiae)
chr16_-_20364122 6.23 ENST00000396138.4
ENST00000577168.1
uromodulin
chr16_+_84328429 6.15 ENST00000568638.1
WAP four-disulfide core domain 1
chr3_-_50340996 6.15 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
hyaluronoglucosaminidase 1
chrX_+_153237740 6.12 ENST00000369982.4
transmembrane protein 187
chr3_+_37284824 6.10 ENST00000431105.1
golgin A4
chr17_-_79818354 6.09 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr17_-_26694979 6.08 ENST00000438614.1
vitronectin
chr12_+_53443680 6.06 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr16_-_55867146 6.05 ENST00000422046.2
carboxylesterase 1
chr6_-_62996066 5.96 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr8_-_27457494 5.93 ENST00000521770.1
clusterin
chr17_-_26695013 5.92 ENST00000555059.2
Homeobox protein SEBOX
chr3_-_127541194 5.92 ENST00000453507.2
monoglyceride lipase
chr4_-_186733363 5.91 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr18_+_29171689 5.90 ENST00000237014.3
transthyretin
chr16_+_81812863 5.86 ENST00000359376.3
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_32671236 5.82 ENST00000537469.1
ENST00000291358.6
IQ motif containing C
chr3_+_10857885 5.82 ENST00000254488.2
ENST00000454147.1
solute carrier family 6 (neurotransmitter transporter), member 11
chr16_+_84328252 5.81 ENST00000219454.5
WAP four-disulfide core domain 1
chrX_+_43515467 5.78 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr17_+_73717551 5.77 ENST00000450894.3
integrin, beta 4
chr9_-_137809718 5.76 ENST00000371806.3
ficolin (collagen/fibrinogen domain containing) 1
chr19_+_17982747 5.74 ENST00000222248.3
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr17_+_73717407 5.73 ENST00000579662.1
integrin, beta 4
chr12_-_117537240 5.71 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr17_+_7461781 5.71 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr11_-_64885111 5.70 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr17_-_18585541 5.69 ENST00000285274.5
ENST00000545289.1
ENST00000580145.1
zinc finger protein 286B
chr6_+_31555045 5.67 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr8_-_11710979 5.66 ENST00000415599.2
cathepsin B
chr6_+_31554456 5.61 ENST00000339530.4
leukocyte specific transcript 1
chr19_+_45582453 5.57 ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
ENST00000587566.1
gem (nuclear organelle) associated protein 7
MAP/microtubule affinity-regulating kinase 4
chr9_-_33264676 5.52 ENST00000472232.3
ENST00000379704.2
BCL2-associated athanogene
chr3_+_49027308 5.50 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr16_-_20364030 5.50 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
uromodulin
chr10_+_99258625 5.49 ENST00000370664.3
ubiquitin domain containing 1
chr5_-_115872142 5.48 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_26903900 5.48 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
aldolase C, fructose-bisphosphate
chr7_-_37488834 5.47 ENST00000310758.4
engulfment and cell motility 1
chr19_+_17326521 5.46 ENST00000593597.1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr3_+_183903811 5.46 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr17_-_42277203 5.45 ENST00000587097.1
ataxin 7-like 3
chr19_+_7069690 5.43 ENST00000439035.2
zinc finger protein 557
chr13_-_37494365 5.42 ENST00000350148.5
SMAD family member 9
chr5_-_134914673 5.41 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr8_-_90769422 5.41 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
chr20_+_30640004 5.40 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
hemopoietic cell kinase
chr17_+_7210852 5.27 ENST00000576930.1
eukaryotic translation initiation factor 5A
chr17_-_79269067 5.25 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chrX_-_38186811 5.24 ENST00000318842.7
retinitis pigmentosa GTPase regulator
chr8_-_27472198 5.23 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
clusterin
chr17_-_17875688 5.23 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
target of myb1-like 2 (chicken)
chr3_-_52479043 5.22 ENST00000231721.2
ENST00000475739.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr10_-_98273668 5.19 ENST00000357947.3
tolloid-like 2
chr1_+_156698708 5.19 ENST00000519086.1
ribosomal RNA adenine dimethylase domain containing 1
chr6_-_39902185 5.18 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
molybdenum cofactor synthesis 1
chr3_+_46921732 5.18 ENST00000418619.1
parathyroid hormone 1 receptor
chrX_-_106960285 5.16 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr13_-_37494391 5.15 ENST00000379826.4
SMAD family member 9
chr1_+_220960033 5.12 ENST00000366910.5
mitochondrial amidoxime reducing component 1
chr4_-_121843985 5.11 ENST00000264808.3
ENST00000428209.2
ENST00000515109.1
ENST00000394435.2
PR domain containing 5
chr11_+_116700614 5.09 ENST00000375345.1
apolipoprotein C-III
chr2_-_73869508 5.07 ENST00000272425.3
N-acetyltransferase 8 (GCN5-related, putative)
chr14_-_88459182 5.04 ENST00000544807.2
galactosylceramidase
chr11_+_116700600 5.00 ENST00000227667.3
apolipoprotein C-III
chr19_+_859654 4.98 ENST00000592860.1
complement factor D (adipsin)
chr19_+_18794470 4.96 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr16_-_75241050 4.95 ENST00000303037.8
chymotrypsinogen B2
chr6_+_31554962 4.94 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
leukocyte specific transcript 1
chr13_-_45150392 4.94 ENST00000501704.2
TSC22 domain family, member 1
chr10_-_90712520 4.91 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr10_-_70092671 4.90 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr1_+_205473720 4.89 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr22_+_41865109 4.89 ENST00000216254.4
ENST00000396512.3
aconitase 2, mitochondrial
chr17_-_8021710 4.88 ENST00000380149.1
ENST00000448843.2
arachidonate lipoxygenase 3
chr17_-_64216748 4.86 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_237167718 4.85 ENST00000464121.2
metallothionein 1H-like 1
chr8_+_9046503 4.85 ENST00000512942.2
RP11-10A14.5
chr7_-_5553369 4.82 ENST00000453700.3
ENST00000382368.3
F-box and leucine-rich repeat protein 18
chr12_+_53440753 4.82 ENST00000379902.3
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_61717535 4.80 ENST00000534553.1
ENST00000301774.9
bestrophin 1
chr22_+_38453207 4.80 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr17_-_617949 4.79 ENST00000401468.3
ENST00000574029.1
ENST00000291074.5
ENST00000571805.1
ENST00000437048.2
ENST00000446250.2
vacuolar protein sorting 53 homolog (S. cerevisiae)
chr14_+_24583836 4.79 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr1_+_32042131 4.76 ENST00000271064.7
ENST00000537531.1
tubulointerstitial nephritis antigen-like 1
chr17_-_2614927 4.76 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr6_-_150039249 4.75 ENST00000543571.1
large tumor suppressor kinase 1
chr6_+_41040678 4.75 ENST00000341376.6
ENST00000353205.5
nuclear transcription factor Y, alpha
chr6_+_80816372 4.71 ENST00000545529.1
branched chain keto acid dehydrogenase E1, beta polypeptide
chrX_-_131623982 4.68 ENST00000370844.1
muscleblind-like splicing regulator 3
chr4_+_668348 4.67 ENST00000511290.1
myosin, light chain 5, regulatory
chr1_-_17445930 4.66 ENST00000375486.4
ENST00000375481.1
ENST00000444885.2
peptidyl arginine deiminase, type II
chr20_+_54967409 4.65 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr19_+_35629702 4.64 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr6_+_43739697 4.62 ENST00000230480.6
vascular endothelial growth factor A
chr8_+_21911054 4.60 ENST00000519850.1
ENST00000381470.3
dematin actin binding protein
chr1_+_160085501 4.59 ENST00000361216.3
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr15_+_92397051 4.59 ENST00000424469.2
solute carrier organic anion transporter family, member 3A1
chr19_-_40919271 4.59 ENST00000291825.7
ENST00000324001.7
periaxin
chr15_-_35047166 4.59 ENST00000290374.4
gap junction protein, delta 2, 36kDa
chr1_+_47603109 4.58 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
cytochrome P450, family 4, subfamily A, polypeptide 22
chr16_+_84853580 4.57 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
cysteine-rich secretory protein LCCL domain containing 2
chr6_-_31763408 4.55 ENST00000444930.2
valyl-tRNA synthetase
chr11_+_1891380 4.55 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr22_-_51021397 4.55 ENST00000406938.2
choline kinase beta
chr1_-_151345159 4.55 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
selenium binding protein 1
chr2_+_90248739 4.54 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr12_+_50355647 4.54 ENST00000293599.6
aquaporin 5
chr3_+_32147997 4.53 ENST00000282541.5
glycerol-3-phosphate dehydrogenase 1-like
chr11_+_64323428 4.49 ENST00000377581.3
solute carrier family 22 (organic anion/urate transporter), member 11
chr1_+_27719148 4.46 ENST00000374024.3
G protein-coupled receptor 3
chr16_-_55866997 4.46 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr12_-_56101647 4.45 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
integrin, alpha 7
chr19_-_13617037 4.45 ENST00000360228.5
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr6_-_39902160 4.44 ENST00000340692.5
molybdenum cofactor synthesis 1
chr11_-_119599794 4.44 ENST00000264025.3
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr6_+_31554636 4.43 ENST00000433492.1
leukocyte specific transcript 1
chr7_-_27183263 4.39 ENST00000222726.3
homeobox A5
chr19_-_50316517 4.38 ENST00000313777.4
ENST00000445575.2
fuzzy planar cell polarity protein
chr16_+_30386098 4.36 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr10_-_120514720 4.35 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chrX_-_131623874 4.35 ENST00000436215.1
muscleblind-like splicing regulator 3
chr10_+_114135952 4.35 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
acyl-CoA synthetase long-chain family member 5
chr16_-_31439735 4.34 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 28.3 GO:0030185 nitric oxide transport(GO:0030185)
5.9 29.6 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.6 18.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
3.5 13.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
3.4 10.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.4 10.1 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
3.3 13.2 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
3.2 19.4 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
3.1 9.4 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
3.1 28.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
3.1 12.4 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
2.9 8.7 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.8 13.9 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
2.7 11.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
2.6 7.9 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
2.5 2.5 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
2.5 14.9 GO:0070560 protein secretion by platelet(GO:0070560)
2.4 4.7 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
2.4 9.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.3 6.9 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
2.3 6.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
2.2 8.8 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
2.2 2.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
2.2 10.9 GO:0048807 female genitalia morphogenesis(GO:0048807)
2.1 27.7 GO:0030321 transepithelial chloride transport(GO:0030321)
2.1 6.3 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
2.1 8.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
2.1 10.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
2.1 2.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.0 14.2 GO:0032119 sequestering of zinc ion(GO:0032119)
2.0 6.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
2.0 4.0 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
2.0 7.9 GO:0071231 cellular response to folic acid(GO:0071231)
2.0 5.9 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
2.0 5.9 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
1.9 5.8 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.9 13.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.9 7.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.9 9.5 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
1.9 9.5 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.9 11.2 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.8 18.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.8 5.4 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.8 1.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.8 5.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.8 8.8 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.7 11.8 GO:0042126 nitrate metabolic process(GO:0042126)
1.7 5.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.7 8.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.7 1.7 GO:0090212 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
1.7 5.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.7 6.6 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
1.6 6.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
1.6 8.1 GO:0071918 urea transmembrane transport(GO:0071918)
1.6 7.9 GO:0030035 microspike assembly(GO:0030035)
1.6 7.8 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.5 3.1 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
1.5 4.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
1.5 4.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.5 4.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.5 4.5 GO:0015670 carbon dioxide transport(GO:0015670)
1.5 7.6 GO:0021759 globus pallidus development(GO:0021759)
1.5 7.4 GO:0006543 glutamine catabolic process(GO:0006543)
1.5 5.9 GO:0042412 taurine biosynthetic process(GO:0042412)
1.5 4.4 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
1.5 2.9 GO:0008380 RNA splicing(GO:0008380)
1.4 5.7 GO:0035624 receptor transactivation(GO:0035624)
1.4 7.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
1.4 7.0 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
1.4 4.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.4 9.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.4 4.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.4 4.1 GO:0015793 glycerol transport(GO:0015793)
1.3 4.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
1.3 2.7 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
1.3 8.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.3 5.3 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
1.3 1.3 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
1.3 1.3 GO:0006789 bilirubin conjugation(GO:0006789)
1.3 5.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
1.3 10.4 GO:0034587 piRNA metabolic process(GO:0034587)
1.3 5.2 GO:0003095 pressure natriuresis(GO:0003095)
1.2 3.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.2 3.7 GO:0018199 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) peptidyl-glutamine modification(GO:0018199) isopeptide cross-linking(GO:0018262)
1.2 3.6 GO:0007538 primary sex determination(GO:0007538)
1.2 3.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.2 3.6 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.2 9.6 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
1.2 8.3 GO:0010269 response to selenium ion(GO:0010269)
1.2 7.0 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.1 3.4 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.1 3.4 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
1.1 5.7 GO:0019532 oxalate transport(GO:0019532)
1.1 3.4 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.1 3.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.1 2.2 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
1.1 3.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.1 6.6 GO:0022614 membrane to membrane docking(GO:0022614)
1.1 1.1 GO:0048668 collateral sprouting(GO:0048668) regulation of collateral sprouting(GO:0048670) positive regulation of collateral sprouting(GO:0048672)
1.1 9.8 GO:0015705 iodide transport(GO:0015705)
1.1 3.3 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.1 7.5 GO:0002933 lipid hydroxylation(GO:0002933)
1.1 3.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.1 11.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.1 5.3 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
1.1 2.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
1.0 2.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
1.0 3.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
1.0 1.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
1.0 4.0 GO:0014827 intestine smooth muscle contraction(GO:0014827)
1.0 19.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
1.0 77.5 GO:0006953 acute-phase response(GO:0006953)
1.0 5.9 GO:0072716 response to actinomycin D(GO:0072716)
1.0 11.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.0 1.0 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.0 1.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
1.0 10.6 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
1.0 2.9 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.9 4.7 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.9 1.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.9 8.4 GO:0015747 urate transport(GO:0015747)
0.9 4.7 GO:0021553 olfactory nerve development(GO:0021553)
0.9 2.8 GO:0001300 chronological cell aging(GO:0001300)
0.9 4.6 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.9 2.7 GO:0048627 myoblast development(GO:0048627)
0.9 1.8 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.9 8.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.9 6.3 GO:0034378 chylomicron assembly(GO:0034378)
0.9 2.7 GO:0061055 myotome development(GO:0061055)
0.9 5.4 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.9 3.6 GO:0044375 regulation of peroxisome size(GO:0044375)
0.9 3.6 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.9 3.6 GO:0032899 regulation of neurotrophin production(GO:0032899)
0.9 1.7 GO:0001575 globoside metabolic process(GO:0001575)
0.9 1.7 GO:0090009 primitive streak formation(GO:0090009)
0.9 17.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.9 6.0 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.9 3.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.8 2.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.8 1.7 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.8 10.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.8 5.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.8 2.5 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.8 8.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.8 4.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.8 2.5 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.8 3.3 GO:0019046 release from viral latency(GO:0019046)
0.8 8.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.8 4.9 GO:0090131 mesenchyme migration(GO:0090131)
0.8 0.8 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.8 3.2 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.8 3.2 GO:0001757 somite specification(GO:0001757)
0.8 8.9 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.8 3.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.8 4.8 GO:0006196 AMP catabolic process(GO:0006196)
0.8 20.0 GO:0001502 cartilage condensation(GO:0001502)
0.8 1.6 GO:0060018 astrocyte fate commitment(GO:0060018)
0.8 4.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.8 4.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.8 3.2 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.8 4.0 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.8 9.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.8 1.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.8 4.6 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.8 6.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.8 2.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.8 3.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.8 2.3 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.8 3.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.8 6.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8 4.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.8 3.8 GO:0032571 response to vitamin K(GO:0032571)
0.8 3.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 5.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.7 1.5 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.7 2.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.7 1.5 GO:0035962 response to interleukin-13(GO:0035962)
0.7 1.4 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.7 1.4 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.7 7.1 GO:0015886 heme transport(GO:0015886)
0.7 4.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.7 2.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.7 7.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.7 1.4 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.7 9.9 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 4.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.7 2.1 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.7 2.1 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.7 4.9 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.7 6.1 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.7 3.4 GO:0002159 desmosome assembly(GO:0002159)
0.7 2.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.7 0.7 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.7 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.7 10.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.7 5.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 17.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.7 4.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.7 2.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.7 3.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.7 2.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.6 1.9 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.6 1.3 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.6 1.9 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740)
0.6 3.9 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.6 4.5 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.6 3.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.6 9.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.6 2.5 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.6 9.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.6 2.5 GO:0060214 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.6 3.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6 1.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.6 10.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 3.1 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.6 10.5 GO:0006265 DNA topological change(GO:0006265)
0.6 1.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 1.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.6 3.0 GO:0060033 anatomical structure regression(GO:0060033)
0.6 4.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.6 1.8 GO:1904647 response to rotenone(GO:1904647)
0.6 0.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.6 1.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.6 4.2 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.6 2.4 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.6 1.8 GO:0060529 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.6 3.0 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.6 3.5 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.6 10.0 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.6 2.9 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.6 2.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.6 2.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.6 4.6 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.6 3.4 GO:0018343 protein farnesylation(GO:0018343)
0.6 2.8 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 1.7 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.6 7.7 GO:0035878 nail development(GO:0035878)
0.5 8.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.5 1.6 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.5 1.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 9.8 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.5 6.0 GO:0030238 male sex determination(GO:0030238)
0.5 4.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.5 2.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.5 35.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.5 2.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 16.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.5 1.6 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.5 1.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.5 0.5 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.5 1.5 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.5 1.5 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.5 5.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 1.5 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.5 2.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 13.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5 2.5 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.5 2.0 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.5 1.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.5 4.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.5 1.9 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.5 1.0 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.5 5.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.5 1.4 GO:0009635 response to herbicide(GO:0009635) negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.5 1.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 9.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.5 4.3 GO:0030091 protein repair(GO:0030091)
0.5 3.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 3.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.5 2.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 1.9 GO:0001842 neural fold formation(GO:0001842)
0.5 3.7 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5 4.6 GO:0015732 prostaglandin transport(GO:0015732)
0.5 2.7 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 1.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.5 1.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.5 5.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.5 3.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 1.4 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.5 1.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.4 0.9 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 1.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 3.6 GO:0071318 cellular response to ATP(GO:0071318)
0.4 2.7 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.4 3.5 GO:1900113 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.4 1.8 GO:0015808 L-alanine transport(GO:0015808)
0.4 0.9 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.4 1.7 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.4 3.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 1.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 1.7 GO:0032455 nerve growth factor processing(GO:0032455)
0.4 0.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.4 1.7 GO:1901727 protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.4 1.7 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.4 5.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.4 0.8 GO:0061386 closure of optic fissure(GO:0061386)
0.4 2.1 GO:1904124 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.4 0.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 1.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.4 1.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.4 2.5 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.4 2.0 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 5.7 GO:0046697 decidualization(GO:0046697)
0.4 0.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 3.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.4 1.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.4 2.4 GO:0043307 eosinophil activation(GO:0043307)
0.4 1.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.4 1.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.4 13.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 4.4 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.4 1.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 1.6 GO:0060074 synapse maturation(GO:0060074)
0.4 1.2 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.4 0.8 GO:0001812 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.4 7.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 3.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.4 2.0 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.4 1.6 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.4 1.6 GO:0071625 vocalization behavior(GO:0071625)
0.4 3.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.4 3.9 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.4 2.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 1.9 GO:0001555 oocyte growth(GO:0001555)
0.4 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 5.8 GO:0042420 dopamine catabolic process(GO:0042420)
0.4 1.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.4 36.6 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.4 1.9 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4 4.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.4 9.7 GO:0097503 sialylation(GO:0097503)
0.4 1.5 GO:0070384 Harderian gland development(GO:0070384)
0.4 2.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 5.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.4 3.7 GO:0099612 protein localization to axon(GO:0099612)
0.4 2.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 3.3 GO:0048102 autophagic cell death(GO:0048102)
0.4 1.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.4 4.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.4 3.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 1.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 0.4 GO:0009826 unidimensional cell growth(GO:0009826)
0.4 2.8 GO:0070995 NADPH oxidation(GO:0070995)
0.4 2.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 0.7 GO:0003285 septum secundum development(GO:0003285)
0.4 2.8 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 2.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 0.7 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.3 1.0 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 2.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 5.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.0 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 2.4 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.3 1.7 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.3 10.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.3 1.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.3 1.4 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.3 2.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 2.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.3 0.7 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.3 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 5.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 2.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 3.6 GO:0006600 creatine metabolic process(GO:0006600)
0.3 2.6 GO:0071313 cellular response to caffeine(GO:0071313)
0.3 4.6 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.6 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.3 5.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 1.3 GO:0021633 optic nerve structural organization(GO:0021633)
0.3 3.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 0.6 GO:0010040 response to iron(II) ion(GO:0010040)
0.3 3.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 8.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.3 5.0 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.9 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 4.0 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.3 4.6 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.3 2.4 GO:0046618 drug export(GO:0046618)
0.3 0.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 1.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 3.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 4.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.3 1.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 5.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 1.4 GO:0030070 insulin processing(GO:0030070)
0.3 1.7 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.3 3.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.3 3.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 5.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3 8.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 6.4 GO:0016578 histone deubiquitination(GO:0016578)
0.3 5.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 2.2 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.3 4.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 2.2 GO:0016926 protein desumoylation(GO:0016926)
0.3 1.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.6 GO:0050808 synapse organization(GO:0050808)
0.3 1.1 GO:0033574 response to testosterone(GO:0033574)
0.3 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.3 4.3 GO:0030048 actin filament-based movement(GO:0030048)
0.3 1.9 GO:0002544 chronic inflammatory response(GO:0002544)
0.3 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.3 1.8 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 0.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 1.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 1.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.3 5.1 GO:0015872 dopamine transport(GO:0015872)
0.3 2.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.3 2.8 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.3 3.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.3 2.0 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 3.7 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 0.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 3.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 17.7 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.2 4.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.2 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 4.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 2.1 GO:0048265 response to pain(GO:0048265)
0.2 2.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.2 16.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.2 4.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.7 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.2 0.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 3.0 GO:0048266 behavioral response to pain(GO:0048266)
0.2 2.1 GO:0060973 cell migration involved in heart development(GO:0060973)
0.2 1.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 3.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 2.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 2.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.2 0.5 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 2.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.2 4.7 GO:0001755 neural crest cell migration(GO:0001755)
0.2 1.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 2.0 GO:0050890 cognition(GO:0050890)
0.2 6.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.2 1.1 GO:0097105 postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 3.2 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.2 8.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.2 2.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 3.4 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.2 0.4 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.2 2.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation(GO:0030497) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 6.8 GO:0007140 male meiosis(GO:0007140)
0.2 2.5 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.2 5.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.2 4.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 2.7 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.2 5.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 12.1 GO:0006968 cellular defense response(GO:0006968)
0.2 0.8 GO:0015816 glycine transport(GO:0015816)
0.2 15.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 5.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 1.2 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.2 1.0 GO:0070383 DNA cytosine deamination(GO:0070383)
0.2 1.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.2 3.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.2 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 6.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 1.3 GO:0045007 depurination(GO:0045007)
0.2 2.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 2.5 GO:0022011 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 1.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 1.8 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.2 2.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.2 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 7.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 0.3 GO:1990834 response to odorant(GO:1990834)
0.2 1.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 2.1 GO:0001525 angiogenesis(GO:0001525)
0.2 4.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 11.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 0.5 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.5 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 5.6 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 2.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 0.3 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.2 1.7 GO:1903037 regulation of leukocyte cell-cell adhesion(GO:1903037)
0.2 3.8 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 2.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 2.3 GO:0010470 regulation of gastrulation(GO:0010470)
0.2 1.9 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.2 0.5 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 0.9 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 2.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 1.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 0.1 GO:0030323 respiratory tube development(GO:0030323)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.3 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.1 2.5 GO:0030220 platelet formation(GO:0030220)
0.1 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.9 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 2.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 1.3 GO:0014029 neural crest formation(GO:0014029)
0.1 3.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 2.1 GO:0006833 water transport(GO:0006833)
0.1 4.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 1.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.5 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 3.6 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 3.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.2 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 0.4 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 6.9 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.1 1.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 1.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 2.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.3 GO:0014061 regulation of norepinephrine secretion(GO:0014061)
0.1 8.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.4 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 2.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 0.7 GO:0006284 base-excision repair(GO:0006284)
0.1 0.4 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.4 GO:0072553 terminal button organization(GO:0072553)
0.1 1.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.4 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.1 2.6 GO:0097659 nucleic acid-templated transcription(GO:0097659)
0.1 0.9 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.2 GO:0097186 amelogenesis(GO:0097186)
0.1 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.6 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 3.0 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.1 1.4 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 5.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 6.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 8.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.1 1.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.6 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 4.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.7 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 1.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 1.3 GO:0031670 cellular response to nutrient(GO:0031670)
0.1 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.0 GO:0033198 response to ATP(GO:0033198)
0.1 2.6 GO:0042596 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) fear response(GO:0042596)
0.1 0.3 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 5.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 5.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0046351 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) disaccharide biosynthetic process(GO:0046351)
0.1 2.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 3.5 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1 2.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.2 GO:0002076 osteoblast development(GO:0002076)
0.1 0.5 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 1.2 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 1.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 2.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 3.7 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 4.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 4.9 GO:0030574 collagen catabolic process(GO:0030574)
0.1 1.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.7 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 3.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 1.3 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 2.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 1.1 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.0 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 0.6 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 1.0 GO:0045576 mast cell activation(GO:0045576)
0.1 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 3.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 6.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 0.8 GO:0043065 positive regulation of apoptotic process(GO:0043065)
0.1 1.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.6 GO:0045639 positive regulation of myeloid cell differentiation(GO:0045639)
0.1 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.7 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.1 0.4 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 0.6 GO:0032060 bleb assembly(GO:0032060)
0.1 1.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.3 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.1 0.8 GO:0006897 endocytosis(GO:0006897)
0.1 0.6 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.7 GO:0033622 integrin activation(GO:0033622)
0.1 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.6 GO:0060326 cell chemotaxis(GO:0060326)
0.1 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 4.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.1 1.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 2.1 GO:0008585 female gonad development(GO:0008585) development of primary female sexual characteristics(GO:0046545)
0.0 0.9 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.6 GO:0072337 modified amino acid transport(GO:0072337)
0.0 2.1 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.7 GO:0048512 circadian behavior(GO:0048512)
0.0 1.9 GO:0008366 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 0.9 GO:0002687 positive regulation of leukocyte migration(GO:0002687)
0.0 0.8 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.4 GO:0036507 protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508)
0.0 2.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0009887 organ morphogenesis(GO:0009887)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 2.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.6 GO:0010165 response to X-ray(GO:0010165)
0.0 0.8 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.8 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0048289 T-helper 1 cell lineage commitment(GO:0002296) isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0072431 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:2000109 regulation of macrophage apoptotic process(GO:2000109)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.7 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.5 GO:0048515 spermatid development(GO:0007286) spermatid differentiation(GO:0048515)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.0 GO:0008343 adult feeding behavior(GO:0008343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
3.6 14.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
3.2 9.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
3.0 8.9 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
2.4 12.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
2.0 16.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.0 6.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
2.0 29.6 GO:0030478 actin cap(GO:0030478)
1.9 16.7 GO:0005579 membrane attack complex(GO:0005579)
1.8 5.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.7 3.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
1.6 9.5 GO:0097433 dense body(GO:0097433)
1.6 7.8 GO:0045298 tubulin complex(GO:0045298)
1.5 6.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.5 8.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.3 12.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.2 3.7 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.2 4.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.2 4.8 GO:1990745 EARP complex(GO:1990745)
1.2 17.9 GO:0042627 chylomicron(GO:0042627)
1.1 4.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.1 5.3 GO:0005899 insulin receptor complex(GO:0005899)
1.0 1.0 GO:0061689 tricellular tight junction(GO:0061689)
1.0 2.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.9 110.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.9 3.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.9 2.8 GO:0072563 endothelial microparticle(GO:0072563)
0.9 4.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.9 3.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.9 4.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.8 14.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.8 5.7 GO:0036021 endolysosome lumen(GO:0036021)
0.8 3.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.8 4.0 GO:0036398 TCR signalosome(GO:0036398)
0.8 3.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.8 3.2 GO:0043293 apoptosome(GO:0043293)
0.8 19.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.8 13.9 GO:0005922 connexon complex(GO:0005922)
0.7 8.9 GO:0005642 annulate lamellae(GO:0005642)
0.7 8.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.7 2.8 GO:1990031 pinceau fiber(GO:1990031)
0.7 5.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 3.5 GO:0089701 U2AF(GO:0089701)
0.7 13.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 11.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.7 32.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.7 8.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.7 3.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.7 1.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 3.2 GO:0071546 pi-body(GO:0071546)
0.6 4.4 GO:0019815 B cell receptor complex(GO:0019815)
0.6 3.7 GO:0005927 muscle tendon junction(GO:0005927)
0.6 9.8 GO:0097512 cardiac myofibril(GO:0097512)
0.6 7.2 GO:0031906 late endosome lumen(GO:0031906)
0.6 9.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 7.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6 1.8 GO:0097440 apical dendrite(GO:0097440)
0.6 4.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.6 2.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 1.7 GO:0060187 cell pole(GO:0060187)
0.6 2.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.6 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 3.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 2.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.5 5.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 3.7 GO:0000813 ESCRT I complex(GO:0000813)
0.5 2.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 7.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 17.0 GO:0005901 caveola(GO:0005901)
0.5 5.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 11.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 6.6 GO:0046930 pore complex(GO:0046930)
0.4 2.6 GO:1990769 proximal neuron projection(GO:1990769)
0.4 7.4 GO:0031904 endosome lumen(GO:0031904)
0.4 7.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 6.4 GO:0000124 SAGA complex(GO:0000124)
0.4 5.1 GO:0031045 dense core granule(GO:0031045)
0.4 3.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.4 3.8 GO:0044327 dendritic spine head(GO:0044327)
0.4 4.5 GO:0042788 polysomal ribosome(GO:0042788)
0.4 2.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.4 8.1 GO:0005861 troponin complex(GO:0005861)
0.4 28.4 GO:0034707 chloride channel complex(GO:0034707)
0.4 3.2 GO:0033391 chromatoid body(GO:0033391)
0.4 4.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 3.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.4 4.8 GO:0097227 sperm annulus(GO:0097227)
0.4 2.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 2.8 GO:0045179 apical cortex(GO:0045179)
0.3 3.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 2.0 GO:0032010 phagolysosome(GO:0032010)
0.3 2.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 1.6 GO:0032021 NELF complex(GO:0032021)
0.3 11.7 GO:0035580 specific granule lumen(GO:0035580)
0.3 4.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 4.3 GO:0036038 MKS complex(GO:0036038)
0.3 2.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.3 4.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 2.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 2.3 GO:0002080 acrosomal membrane(GO:0002080)
0.3 7.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.3 3.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 1.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.3 3.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 4.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 2.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 0.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 2.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 4.4 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 26.8 GO:0005796 Golgi lumen(GO:0005796)
0.2 0.7 GO:0005593 FACIT collagen trimer(GO:0005593)
0.2 2.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 4.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 4.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 9.7 GO:0008305 integrin complex(GO:0008305)
0.2 3.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 11.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 4.5 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 5.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 4.5 GO:0005581 collagen trimer(GO:0005581)
0.2 1.4 GO:0043203 axon hillock(GO:0043203)
0.2 4.9 GO:0071565 nBAF complex(GO:0071565)
0.2 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.2 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.5 GO:0043194 axon initial segment(GO:0043194)
0.2 6.2 GO:0000795 synaptonemal complex(GO:0000795)
0.2 9.5 GO:0016235 aggresome(GO:0016235)
0.2 1.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 3.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 11.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 1.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 9.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 0.8 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 5.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 14.6 GO:0005776 autophagosome(GO:0005776)
0.2 3.3 GO:0070461 SAGA-type complex(GO:0070461)
0.2 10.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 4.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 19.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 2.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 18.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 5.8 GO:0097546 ciliary base(GO:0097546)
0.1 3.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 19.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 5.8 GO:0001533 cornified envelope(GO:0001533)
0.1 6.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 4.2 GO:0042629 mast cell granule(GO:0042629)
0.1 6.3 GO:0043195 terminal bouton(GO:0043195)
0.1 1.7 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 17.5 GO:0098793 presynapse(GO:0098793)
0.1 2.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 181.7 GO:0005615 extracellular space(GO:0005615)
0.1 6.5 GO:0005811 lipid particle(GO:0005811)
0.1 3.6 GO:0043679 axon terminus(GO:0043679)
0.1 6.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 6.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 1.3 GO:0032589 neuron projection membrane(GO:0032589)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 2.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 10.9 GO:0055037 recycling endosome(GO:0055037)
0.1 1.9 GO:0031201 SNARE complex(GO:0031201)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.6 GO:0043235 receptor complex(GO:0043235)
0.1 2.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 3.6 GO:0002102 podosome(GO:0002102)
0.1 14.8 GO:0001726 ruffle(GO:0001726)
0.1 6.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 9.9 GO:0016605 PML body(GO:0016605)
0.1 3.1 GO:0000791 euchromatin(GO:0000791)
0.1 13.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 3.3 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 4.1 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.9 GO:0017119 Golgi transport complex(GO:0017119)
0.1 90.4 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.1 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 4.3 GO:0016324 apical plasma membrane(GO:0016324)
0.1 5.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.8 GO:0030133 transport vesicle(GO:0030133)
0.0 0.7 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 1.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 5.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 5.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:0005769 early endosome(GO:0005769)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 7.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
4.6 13.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
3.7 11.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
3.6 10.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
3.1 12.3 GO:0008431 vitamin E binding(GO:0008431)
2.9 11.8 GO:0008940 nitrate reductase activity(GO:0008940)
2.9 5.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
2.8 8.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.6 7.9 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
2.5 15.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
2.5 10.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.5 10.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.5 29.6 GO:0045159 myosin II binding(GO:0045159)
2.4 14.5 GO:0030492 hemoglobin binding(GO:0030492)
2.4 7.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
2.4 19.0 GO:0008131 primary amine oxidase activity(GO:0008131)
2.3 13.9 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
2.2 13.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.2 11.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.1 10.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
2.1 10.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
2.1 10.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.0 6.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.0 6.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
2.0 10.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
2.0 7.9 GO:0061714 folic acid receptor activity(GO:0061714)
2.0 5.9 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
2.0 13.7 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
2.0 5.9 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
2.0 7.8 GO:0099609 microtubule lateral binding(GO:0099609)
1.9 7.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.9 7.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
1.7 26.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.7 8.7 GO:0004995 tachykinin receptor activity(GO:0004995)
1.7 3.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
1.7 13.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.7 5.1 GO:1904288 BAT3 complex binding(GO:1904288)
1.7 5.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.6 6.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.6 8.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.5 4.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.5 4.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
1.5 4.6 GO:0004103 choline kinase activity(GO:0004103)
1.5 6.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
1.5 3.0 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
1.5 7.4 GO:0004359 glutaminase activity(GO:0004359)
1.5 5.9 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.5 8.8 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.5 5.8 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.4 7.0 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.4 4.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.4 4.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
1.3 4.0 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
1.3 4.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.3 3.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
1.2 3.7 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.2 4.8 GO:0004998 transferrin receptor activity(GO:0004998)
1.2 4.8 GO:0008422 beta-glucosidase activity(GO:0008422)
1.2 5.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.2 4.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.1 4.4 GO:0071253 connexin binding(GO:0071253)
1.1 3.3 GO:0070538 oleic acid binding(GO:0070538)
1.1 17.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.1 3.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.0 5.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0 5.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
1.0 5.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.0 4.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.0 3.0 GO:0032093 SAM domain binding(GO:0032093)
1.0 2.9 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.9 6.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.9 2.8 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.9 2.8 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.9 3.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.9 5.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.9 13.9 GO:0019841 retinol binding(GO:0019841)
0.9 2.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.9 4.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.8 5.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.8 4.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.8 8.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.8 15.1 GO:0019864 IgG binding(GO:0019864)
0.8 89.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.8 1.6 GO:0050780 dopamine receptor binding(GO:0050780)
0.8 39.6 GO:0030546 receptor activator activity(GO:0030546)
0.8 19.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.8 11.8 GO:0005243 gap junction channel activity(GO:0005243)
0.8 2.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.8 7.8 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.8 3.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.8 17.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 2.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 7.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.7 3.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 9.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 4.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.7 2.1 GO:0051379 beta-adrenergic receptor activity(GO:0004939) epinephrine binding(GO:0051379) norepinephrine binding(GO:0051380)
0.7 4.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.7 9.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.7 9.2 GO:0070700 BMP receptor binding(GO:0070700)
0.7 11.9 GO:0038191 neuropilin binding(GO:0038191)
0.7 0.7 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.7 3.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.7 0.7 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.7 3.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.7 13.7 GO:0051787 misfolded protein binding(GO:0051787)
0.7 4.1 GO:0051425 PTB domain binding(GO:0051425)
0.7 2.7 GO:0030172 troponin C binding(GO:0030172)
0.7 2.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.7 2.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.7 3.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.7 36.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.7 2.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.7 6.5 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.6 3.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.6 7.1 GO:0008430 selenium binding(GO:0008430)
0.6 9.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.6 1.9 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.6 6.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.6 3.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 4.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.6 5.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329) quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.6 2.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.6 6.6 GO:0051434 BH3 domain binding(GO:0051434)
0.6 2.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.6 2.9 GO:0002046 opsin binding(GO:0002046)
0.6 4.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.6 2.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.6 8.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.6 5.2 GO:0043426 MRF binding(GO:0043426)
0.6 2.8 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.6 2.2 GO:0045499 chemorepellent activity(GO:0045499)
0.6 2.2 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.6 4.4 GO:0005534 galactose binding(GO:0005534)
0.6 2.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.5 2.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 6.0 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.5 1.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.5 1.6 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5 2.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.5 4.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.5 2.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.5 2.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.5 1.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.5 4.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 2.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.5 2.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 8.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 1.5 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.5 6.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.5 1.5 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.5 6.6 GO:0046870 cadmium ion binding(GO:0046870)
0.5 6.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 2.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5 5.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.5 3.5 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.5 3.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5 8.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.5 2.0 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.5 131.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 2.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.5 1.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 2.4 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.5 3.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.5 2.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 1.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 2.7 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 5.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 9.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 5.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.5 6.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 3.2 GO:0043531 ADP binding(GO:0043531)
0.5 16.7 GO:0008009 chemokine activity(GO:0008009)
0.5 1.4 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.5 3.6 GO:0004111 creatine kinase activity(GO:0004111)
0.4 2.7 GO:0004935 adrenergic receptor activity(GO:0004935)
0.4 11.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 2.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.4 3.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 1.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 0.9 GO:0033265 choline binding(GO:0033265)
0.4 3.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 1.7 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.4 2.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.4 2.9 GO:0004035 alkaline phosphatase activity(GO:0004035) nucleotide diphosphatase activity(GO:0004551)
0.4 4.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 1.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 1.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 2.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 0.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 1.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 2.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 1.6 GO:0031711 bradykinin receptor binding(GO:0031711)
0.4 3.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.4 1.9 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.4 1.2 GO:0070051 fibrinogen binding(GO:0070051)
0.4 2.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.5 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 0.8 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.4 3.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 3.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 1.5 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.4 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 3.7 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 19.8 GO:0019894 kinesin binding(GO:0019894)
0.4 1.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.4 4.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.4 5.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 4.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.4 3.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 2.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 5.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 1.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 1.0 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 2.4 GO:0042608 T cell receptor binding(GO:0042608)
0.3 5.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.3 4.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 5.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 3.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.3 4.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.9 GO:0043532 angiostatin binding(GO:0043532)
0.3 6.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 0.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.3 GO:0010851 cyclase regulator activity(GO:0010851)
0.3 1.9 GO:0031705 bombesin receptor binding(GO:0031705)
0.3 1.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 1.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 2.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.3 3.6 GO:0038132 neuregulin binding(GO:0038132)
0.3 3.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 0.8 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.3 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 12.7 GO:0030507 spectrin binding(GO:0030507)
0.3 2.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 1.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 4.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 2.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 7.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.3 1.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 2.6 GO:0015026 coreceptor activity(GO:0015026)
0.3 3.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 12.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 4.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 4.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.7 GO:0051373 FATZ binding(GO:0051373)
0.2 21.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 4.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 3.3 GO:0035198 miRNA binding(GO:0035198)
0.2 1.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 5.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 5.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 4.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.2 7.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 3.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 4.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 1.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 6.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.7 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 5.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 2.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 3.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 1.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.6 GO:0070984 SET domain binding(GO:0070984)
0.2 8.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 1.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 9.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 7.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 3.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 7.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 9.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 1.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 5.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.2 2.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.9 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.2 8.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 4.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 0.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 6.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 0.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 5.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.2 2.7 GO:0055102 lipase inhibitor activity(GO:0055102)
0.2 1.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 3.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 7.3 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 2.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 1.2 GO:0022839 ion gated channel activity(GO:0022839)
0.2 3.6 GO:0005112 Notch binding(GO:0005112)
0.2 1.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 4.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 13.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 2.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 1.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 14.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 1.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 2.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 2.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 15.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 2.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 4.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.2 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.2 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 4.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.5 GO:0043295 glutathione binding(GO:0043295)
0.1 4.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 4.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.9 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 2.3 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.1 4.5 GO:0008066 glutamate receptor activity(GO:0008066)
0.1 2.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.7 GO:0001016 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1 3.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.2 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.5 GO:0016015 morphogen activity(GO:0016015)
0.1 4.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 2.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 2.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 10.8 GO:0005179 hormone activity(GO:0005179)
0.1 0.7 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 3.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 3.3 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 1.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 4.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 22.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 14.7 GO:0005261 cation channel activity(GO:0005261)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 2.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 2.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.8 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.3 GO:0005507 copper ion binding(GO:0005507)
0.1 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 2.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 1.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 3.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.8 20.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.8 68.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.8 15.7 PID ALK2 PATHWAY ALK2 signaling events
0.7 21.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 31.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.6 38.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.6 2.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.5 9.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 32.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 6.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.4 11.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 2.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.4 16.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 25.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 4.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 2.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 14.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 9.7 PID EPO PATHWAY EPO signaling pathway
0.3 7.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 3.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 6.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 13.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 14.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.3 3.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.3 75.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 10.5 ST GA13 PATHWAY G alpha 13 Pathway
0.3 4.1 PID IFNG PATHWAY IFN-gamma pathway
0.3 2.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.3 4.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 13.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 3.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 9.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 12.7 PID ATM PATHWAY ATM pathway
0.3 13.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 6.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 83.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 16.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 39.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 8.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 9.1 NABA COLLAGENS Genes encoding collagen proteins
0.2 4.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 5.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 7.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 3.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 4.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 1.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 2.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 3.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.0 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 17.3 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.1 3.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 6.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 24.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.6 16.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
1.3 32.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2 24.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.1 25.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.1 7.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.9 30.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8 24.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.8 13.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.8 15.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.6 19.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.6 7.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 1.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.6 6.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.6 16.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 16.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.6 31.6 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.6 10.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 3.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 3.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.5 12.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.5 8.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 7.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.5 7.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.5 8.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 6.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 14.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 2.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 9.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 5.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 6.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 9.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 4.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 4.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 2.7 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.4 19.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 1.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.4 10.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.4 55.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 12.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 5.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 8.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 2.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 1.8 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.4 5.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.4 12.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 10.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.3 4.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 12.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.3 11.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 10.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 7.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 5.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 2.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.3 17.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 2.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 34.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 4.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 8.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 4.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 9.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 4.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.3 4.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 3.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.2 4.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 1.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.2 15.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 9.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 4.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 6.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 13.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 3.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 2.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 17.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 16.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 4.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 3.7 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 3.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 4.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 4.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 7.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 5.3 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.2 6.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 3.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 5.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 11.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 15.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 2.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 3.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 3.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 10.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 7.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 5.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 4.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 1.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 7.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.1 3.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 8.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.5 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 1.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events