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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HINFP

Z-value: 0.55

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Transcription factors associated with HINFP

Gene Symbol Gene ID Gene Info
HINFP
ENSG00000172273.8 histone H4 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HINFPhg19_v2_chr11_+_118992269_1189923340.054.5e-01Click!

Activity profile of HINFP motif

Sorted Z-values of HINFP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_94023873 13.67 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr8_-_27462822 8.97 ENST00000522098.1
CLU
clusterin
chr5_-_136834982 8.58 ENST00000510689.1
ENST00000394945.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_+_6845384 6.60 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr11_-_66336060 6.53 ENST00000310325.5
CTSF
cathepsin F
chr9_+_130965651 6.49 ENST00000475805.1
ENST00000341179.7
ENST00000372923.3
DNM1
dynamin 1
chr9_+_130965677 6.33 ENST00000393594.3
ENST00000486160.1
DNM1
dynamin 1
chr20_-_35492048 6.22 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr4_-_492891 5.91 ENST00000338977.5
ENST00000511833.2
ZNF721
zinc finger protein 721
chr20_-_32031680 5.83 ENST00000217381.2
SNTA1
syntrophin, alpha 1
chr15_+_91643442 5.81 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr3_-_13009168 5.80 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr13_-_77460525 5.69 ENST00000377474.2
ENST00000317765.2
KCTD12
potassium channel tetramerization domain containing 12
chr4_+_166128735 5.57 ENST00000226725.6
KLHL2
kelch-like family member 2
chr1_+_204797749 5.47 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
NFASC
neurofascin
chr12_+_53773944 5.39 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr10_-_131909071 4.86 ENST00000456581.1
LINC00959
long intergenic non-protein coding RNA 959
chr11_-_72353451 4.54 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_+_62104897 4.47 ENST00000415229.2
ENST00000535727.1
ENST00000301776.5
ASRGL1
asparaginase like 1
chr15_+_43803143 4.40 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr16_+_56225248 4.36 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr19_-_49944806 4.32 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr3_-_16555150 4.26 ENST00000334133.4
RFTN1
raftlin, lipid raft linker 1
chr16_+_6069586 4.11 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_+_21392529 4.07 ENST00000425654.2
ENST00000543067.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr17_+_43971643 4.07 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT
microtubule-associated protein tau
chr18_+_268148 4.01 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chr11_-_132813566 3.96 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr17_+_43972010 3.87 ENST00000334239.8
ENST00000446361.3
MAPT
microtubule-associated protein tau
chr3_-_129612394 3.86 ENST00000505616.1
ENST00000426664.2
TMCC1
transmembrane and coiled-coil domain family 1
chr13_-_36705425 3.86 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr9_+_100174344 3.78 ENST00000422139.2
TDRD7
tudor domain containing 7
chr9_-_139922631 3.77 ENST00000341511.6
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chrX_+_21392553 3.71 ENST00000279451.4
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr11_-_6440624 3.58 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr11_-_6440283 3.56 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr17_-_42277203 3.48 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr8_-_9760839 3.44 ENST00000519461.1
ENST00000517675.1
LINC00599
long intergenic non-protein coding RNA 599
chr20_+_30946106 3.42 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr2_-_97304009 3.38 ENST00000431828.1
ENST00000435669.1
ENST00000440133.1
ENST00000448075.1
KANSL3
KAT8 regulatory NSL complex subunit 3
chr10_-_118502070 3.35 ENST00000369209.3
HSPA12A
heat shock 70kDa protein 12A
chr9_-_139922726 3.29 ENST00000265662.5
ENST00000371605.3
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_42402138 3.26 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
SLC25A39
solute carrier family 25, member 39
chr2_-_97304105 3.26 ENST00000599854.1
ENST00000441706.2
KANSL3
KAT8 regulatory NSL complex subunit 3
chr19_+_56186606 3.19 ENST00000085079.7
EPN1
epsin 1
chr22_+_18593446 3.13 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr6_-_139695757 3.06 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr22_-_22221658 2.98 ENST00000544786.1
MAPK1
mitogen-activated protein kinase 1
chr6_+_42847348 2.97 ENST00000493763.1
ENST00000304734.5
RPL7L1
ribosomal protein L7-like 1
chr9_-_139094988 2.96 ENST00000371746.3
LHX3
LIM homeobox 3
chr19_-_14016877 2.87 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr7_-_17980091 2.86 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr3_+_49449636 2.86 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr9_+_139921916 2.84 ENST00000314330.2
C9orf139
chromosome 9 open reading frame 139
chr1_-_92952433 2.76 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr7_+_128095900 2.69 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr13_+_111806055 2.66 ENST00000218789.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr9_+_137533615 2.62 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr9_-_122131696 2.58 ENST00000373964.2
ENST00000265922.3
BRINP1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr20_+_57267669 2.53 ENST00000356091.6
NPEPL1
aminopeptidase-like 1
chr11_-_2162162 2.52 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr13_+_21714653 2.49 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr16_-_2185899 2.49 ENST00000262304.4
ENST00000423118.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chrX_-_38186811 2.48 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr2_+_157292859 2.47 ENST00000438166.2
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr22_-_28197486 2.46 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr11_-_2162468 2.45 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_+_26240414 2.45 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr4_+_123747979 2.44 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr6_+_35310391 2.41 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr17_-_1420182 2.40 ENST00000421807.2
INPP5K
inositol polyphosphate-5-phosphatase K
chr11_+_3876859 2.39 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr19_-_16653226 2.34 ENST00000198939.6
CHERP
calcium homeostasis endoplasmic reticulum protein
chr13_+_21714711 2.28 ENST00000607003.1
ENST00000492245.1
SAP18
Sin3A-associated protein, 18kDa
chr9_-_89562104 2.27 ENST00000298743.7
GAS1
growth arrest-specific 1
chr13_-_41240717 2.25 ENST00000379561.5
FOXO1
forkhead box O1
chr6_+_42847649 2.21 ENST00000424341.2
ENST00000602561.1
RPL7L1
ribosomal protein L7-like 1
chr11_-_73309228 2.19 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr19_+_45754505 2.18 ENST00000262891.4
ENST00000300843.4
MARK4
MAP/microtubule affinity-regulating kinase 4
chr9_+_100174232 2.16 ENST00000355295.4
TDRD7
tudor domain containing 7
chr6_-_33267101 2.14 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr7_-_134143841 2.13 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr9_+_37650945 2.11 ENST00000377765.3
FRMPD1
FERM and PDZ domain containing 1
chr19_-_39523165 2.09 ENST00000509137.2
ENST00000292853.4
FBXO27
F-box protein 27
chr22_-_22221900 2.08 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr3_-_49377499 2.08 ENST00000265560.4
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr19_-_16653325 2.05 ENST00000546361.2
CHERP
calcium homeostasis endoplasmic reticulum protein
chr17_-_1420006 2.03 ENST00000320345.6
ENST00000406424.4
INPP5K
inositol polyphosphate-5-phosphatase K
chr3_-_49131473 2.02 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1
glutamine-rich 1
chr17_-_1419878 1.99 ENST00000449479.1
ENST00000477910.1
ENST00000542125.1
ENST00000575172.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr19_-_45004556 1.98 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr6_+_35310312 1.97 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr4_+_123747834 1.95 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr17_-_4545170 1.92 ENST00000576394.1
ENST00000574640.1
ALOX15
arachidonate 15-lipoxygenase
chr11_-_1593150 1.92 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr7_+_148959262 1.91 ENST00000434415.1
ZNF783
zinc finger family member 783
chr9_-_101017862 1.91 ENST00000375064.1
ENST00000342112.5
TBC1D2
TBC1 domain family, member 2
chr5_-_132166579 1.91 ENST00000378679.3
SHROOM1
shroom family member 1
chr11_+_1411129 1.88 ENST00000308219.9
ENST00000528841.1
ENST00000531197.1
ENST00000308230.5
BRSK2
BR serine/threonine kinase 2
chr3_-_48936272 1.87 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr12_+_7282795 1.86 ENST00000266546.6
CLSTN3
calsyntenin 3
chr17_+_29158962 1.85 ENST00000321990.4
ATAD5
ATPase family, AAA domain containing 5
chr5_-_127873496 1.85 ENST00000508989.1
FBN2
fibrillin 2
chr8_-_144241664 1.85 ENST00000342752.4
LY6H
lymphocyte antigen 6 complex, locus H
chr11_+_119076745 1.80 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr17_-_1419914 1.79 ENST00000397335.3
ENST00000574561.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr6_+_116692102 1.78 ENST00000359564.2
DSE
dermatan sulfate epimerase
chrX_-_38186775 1.75 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr5_-_132073210 1.73 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr8_-_144241432 1.71 ENST00000430474.2
LY6H
lymphocyte antigen 6 complex, locus H
chr17_-_46115122 1.69 ENST00000006101.4
COPZ2
coatomer protein complex, subunit zeta 2
chr6_+_44355257 1.67 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr12_+_69633317 1.65 ENST00000435070.2
CPSF6
cleavage and polyadenylation specific factor 6, 68kDa
chr17_-_4544960 1.65 ENST00000293761.3
ALOX15
arachidonate 15-lipoxygenase
chr13_+_111806083 1.64 ENST00000375736.4
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_49377446 1.63 ENST00000351842.4
ENST00000416417.1
ENST00000415188.1
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr2_-_73053126 1.62 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr1_-_40157345 1.62 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr18_-_268019 1.57 ENST00000261600.6
THOC1
THO complex 1
chr3_+_110790590 1.57 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr2_-_175547571 1.57 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WIPF1
WAS/WASL interacting protein family, member 1
chr22_-_43010928 1.57 ENST00000348657.2
ENST00000252115.5
POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr19_+_36545833 1.56 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chrX_-_53711064 1.56 ENST00000342160.3
ENST00000446750.1
HUWE1
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr22_+_32870661 1.55 ENST00000266087.7
FBXO7
F-box protein 7
chr1_-_212208842 1.54 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7
integrator complex subunit 7
chr4_-_149363662 1.54 ENST00000355292.3
ENST00000358102.3
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr11_+_28131821 1.54 ENST00000379199.2
ENST00000303459.6
METTL15
methyltransferase like 15
chr12_-_90102594 1.53 ENST00000428670.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr17_+_74380683 1.52 ENST00000592299.1
ENST00000590959.1
ENST00000323374.4
SPHK1
sphingosine kinase 1
chrX_-_119695279 1.49 ENST00000336592.6
CUL4B
cullin 4B
chr6_-_89673280 1.47 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr10_-_104179682 1.47 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr8_+_32405785 1.46 ENST00000287842.3
NRG1
neuregulin 1
chr11_+_1411503 1.43 ENST00000526678.1
BRSK2
BR serine/threonine kinase 2
chr22_+_18593507 1.41 ENST00000330423.3
TUBA8
tubulin, alpha 8
chr3_-_156272924 1.40 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr19_-_14117074 1.40 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr12_-_117175819 1.38 ENST00000261318.3
ENST00000536380.1
C12orf49
chromosome 12 open reading frame 49
chr5_-_132073111 1.37 ENST00000403231.1
KIF3A
kinesin family member 3A
chr22_+_17082732 1.35 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr8_+_32406179 1.35 ENST00000405005.3
NRG1
neuregulin 1
chr5_-_142782862 1.32 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr18_-_44336998 1.31 ENST00000315087.7
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr19_+_45596218 1.31 ENST00000421905.1
ENST00000221462.4
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr13_+_25875662 1.27 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
NUPL1
nucleoporin like 1
chr19_+_45596398 1.26 ENST00000544069.2
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr1_-_153919128 1.26 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr16_+_84002234 1.25 ENST00000305202.4
NECAB2
N-terminal EF-hand calcium binding protein 2
chr9_-_101017900 1.24 ENST00000375066.5
TBC1D2
TBC1 domain family, member 2
chr1_+_22351977 1.23 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr15_-_35047166 1.23 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr18_+_43914159 1.21 ENST00000588679.1
ENST00000269439.7
ENST00000543885.1
RNF165
ring finger protein 165
chr2_+_26915584 1.19 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr10_-_62761188 1.18 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr2_-_25564750 1.16 ENST00000321117.5
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_-_62258394 1.16 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr6_-_144329531 1.15 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr2_+_120770581 1.13 ENST00000263713.5
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr2_+_120770645 1.11 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr15_+_101459420 1.10 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr17_-_7518145 1.10 ENST00000250113.7
ENST00000571597.1
FXR2
fragile X mental retardation, autosomal homolog 2
chr6_+_146350622 1.07 ENST00000507907.1
GRM1
glutamate receptor, metabotropic 1
chr2_+_10442993 1.05 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr5_-_142783175 1.01 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr8_-_30670053 1.01 ENST00000518564.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr1_+_28995258 1.00 ENST00000361872.4
ENST00000294409.2
GMEB1
glucocorticoid modulatory element binding protein 1
chr1_-_16563641 0.98 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr9_+_34458771 0.95 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr5_+_113697983 0.95 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_-_200379129 0.94 ENST00000367353.1
ZNF281
zinc finger protein 281
chr17_+_17206635 0.91 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr12_+_57482665 0.90 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr8_+_42995548 0.89 ENST00000458501.2
ENST00000379644.4
HGSNAT
heparan-alpha-glucosaminide N-acetyltransferase
chr17_-_66453562 0.88 ENST00000262139.5
ENST00000546360.1
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr2_-_43453734 0.88 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr17_+_74381343 0.85 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr8_+_32405728 0.85 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr1_-_51796226 0.83 ENST00000451380.1
ENST00000371747.3
ENST00000439482.1
TTC39A
tetratricopeptide repeat domain 39A
chr3_-_38691119 0.81 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
chr3_+_152552685 0.77 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr6_-_35464817 0.77 ENST00000338863.7
TEAD3
TEA domain family member 3
chr1_-_92351769 0.77 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr19_+_14017116 0.77 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr12_-_125052010 0.76 ENST00000458234.1
NCOR2
nuclear receptor corepressor 2
chr12_+_113659234 0.76 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1
two pore segment channel 1
chr13_+_25875785 0.75 ENST00000381747.3
NUPL1
nucleoporin like 1
chr17_-_42276574 0.75 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr17_+_46125707 0.72 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr7_-_140624499 0.71 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr5_-_114598548 0.69 ENST00000379615.3
ENST00000419445.1
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr6_-_35464727 0.67 ENST00000402886.3
TEAD3
TEA domain family member 3
chr5_-_141257954 0.67 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr22_-_19132154 0.66 ENST00000252137.6
DGCR14
DiGeorge syndrome critical region gene 14
chr19_-_15543368 0.65 ENST00000599686.3
WIZ
widely interspaced zinc finger motifs
chr19_-_460996 0.65 ENST00000264554.6
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr4_+_154387480 0.64 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr20_+_3451650 0.63 ENST00000262919.5
ATRN
attractin
chr20_+_3451732 0.60 ENST00000446916.2
ATRN
attractin
chr14_-_92572894 0.56 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
2.4 7.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
2.1 8.2 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
1.7 5.1 GO:0019858 cytosine metabolic process(GO:0019858)
1.6 7.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
1.5 4.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
1.5 9.0 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 4.3 GO:0042137 sequestering of neurotransmitter(GO:0042137)
1.4 7.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.2 3.6 GO:2001303 cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
1.1 3.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.1 2.2 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.9 2.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.9 5.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.9 13.7 GO:0043589 skin morphogenesis(GO:0043589)
0.8 2.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 2.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.8 2.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.8 3.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.7 4.5 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.7 2.2 GO:0003383 apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.7 2.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.7 2.1 GO:0006059 hexitol metabolic process(GO:0006059) response to methylglyoxal(GO:0051595)
0.7 2.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.6 4.4 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.6 4.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.6 2.5 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.6 4.3 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.6 2.3 GO:1902617 response to fluoride(GO:1902617)
0.6 4.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.6 1.7 GO:1990637 response to prolactin(GO:1990637)
0.6 5.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.5 3.5 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.5 3.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.5 2.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.5 4.4 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.4 6.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4 0.4 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.4 5.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 4.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.4 1.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.4 6.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.4 1.6 GO:0035425 autocrine signaling(GO:0035425)
0.4 2.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.4 1.6 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.4 5.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 7.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 1.9 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.3 3.1 GO:0072386 plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.5 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.3 0.9 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.3 0.9 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3 2.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.3 1.0 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.3 1.8 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 0.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 3.3 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.2 5.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 1.5 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.2 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 1.5 GO:0070475 rRNA base methylation(GO:0070475)
0.2 2.1 GO:1903599 negative regulation of oxidative stress-induced neuron death(GO:1903204) positive regulation of mitophagy(GO:1903599)
0.2 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.8 GO:0060406 positive regulation of penile erection(GO:0060406)
0.2 2.0 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 2.6 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 2.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.6 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 4.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 3.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.8 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 4.4 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 7.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 6.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 8.6 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.1 1.9 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 4.4 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 1.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 3.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 2.1 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.9 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 3.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 1.1 GO:0036035 osteoclast development(GO:0036035)
0.1 4.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 1.3 GO:0097503 sialylation(GO:0097503)
0.0 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.6 GO:0007099 centriole replication(GO:0007099)
0.0 2.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.1 GO:1902402 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.4 GO:0007625 grooming behavior(GO:0007625)
0.0 2.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.6 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.6 GO:0007417 central nervous system development(GO:0007417)
0.0 0.7 GO:0007399 nervous system development(GO:0007399)
0.0 5.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 1.0 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) response to antibiotic(GO:0046677) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 4.2 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 1.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.2 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 2.0 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0007041 lysosomal transport(GO:0007041)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0097454 Schwann cell microvillus(GO:0097454)
1.6 7.9 GO:0045298 tubulin complex(GO:0045298)
1.4 16.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 7.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.8 3.1 GO:0016939 kinesin II complex(GO:0016939)
0.7 9.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.6 5.8 GO:0016013 syntrophin complex(GO:0016013)
0.6 7.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.5 4.3 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.5 5.9 GO:0033391 chromatoid body(GO:0033391)
0.5 4.3 GO:0000322 storage vacuole(GO:0000322)
0.5 4.3 GO:0061574 ASAP complex(GO:0061574)
0.4 2.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 2.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 2.1 GO:1990037 Lewy body core(GO:1990037)
0.3 8.4 GO:0033268 node of Ranvier(GO:0033268)
0.3 4.2 GO:0000124 SAGA complex(GO:0000124)
0.3 1.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.3 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 1.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 12.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 0.7 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2 1.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.6 GO:0000346 transcription export complex(GO:0000346)
0.2 1.5 GO:0032039 integrator complex(GO:0032039)
0.2 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 5.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0043235 receptor complex(GO:0043235)
0.1 1.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.9 GO:0036157 outer dynein arm(GO:0036157)
0.1 3.5 GO:0030673 axolemma(GO:0030673)
0.1 10.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 7.4 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 5.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.2 GO:0001741 XY body(GO:0001741)
0.1 5.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.1 7.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 13.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 6.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 14.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 6.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 5.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 4.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.9 GO:0016460 myosin II complex(GO:0016460)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 12.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0034774 secretory granule lumen(GO:0034774)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 4.3 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.9 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0099609 microtubule lateral binding(GO:0099609)
1.5 4.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.4 5.7 GO:0031685 adenosine receptor binding(GO:0031685)
1.4 8.2 GO:0042577 lipid phosphatase activity(GO:0042577)
1.2 3.6 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
1.2 16.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.1 4.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.8 4.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.6 1.9 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.6 2.5 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.6 1.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.6 6.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.5 1.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.5 1.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.5 2.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 9.0 GO:0051787 misfolded protein binding(GO:0051787)
0.4 5.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 7.1 GO:0048156 tau protein binding(GO:0048156)
0.4 1.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 4.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 2.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 3.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 8.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 6.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 1.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 5.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 1.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 3.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 5.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 2.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 3.1 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.7 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.2 1.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.7 GO:0070984 SET domain binding(GO:0070984)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 4.4 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.2 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 4.5 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 4.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 5.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.4 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 4.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 3.1 GO:0030507 spectrin binding(GO:0030507)
0.1 5.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 7.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 6.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 5.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.8 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 7.7 GO:0008017 microtubule binding(GO:0008017)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 6.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 8.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 10.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 16.3 NABA COLLAGENS Genes encoding collagen proteins
0.3 12.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 2.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 7.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 7.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 8.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 8.2 PID AURORA A PATHWAY Aurora A signaling
0.1 7.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 12.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 5.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 13.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 12.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.4 6.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.4 7.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 4.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 7.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 1.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 5.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 8.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 3.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 3.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 4.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 6.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 4.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 9.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels