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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HMX2

Z-value: 1.01

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Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 H6 family homeobox 2

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_95241951 42.86 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr12_+_104680659 28.63 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
TXNRD1
thioredoxin reductase 1
chr2_-_151344172 26.17 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr7_-_87856280 25.91 ENST00000490437.1
ENST00000431660.1
SRI
sorcin
chr7_-_87856303 25.17 ENST00000394641.3
SRI
sorcin
chr10_-_95242044 22.76 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr5_+_167913450 22.70 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr5_+_154393260 20.72 ENST00000435029.4
KIF4B
kinesin family member 4B
chr1_+_99127225 20.08 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chrX_+_119737806 19.15 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr20_+_3776371 18.43 ENST00000245960.5
CDC25B
cell division cycle 25B
chr7_-_7680601 16.89 ENST00000396682.2
RPA3
replication protein A3, 14kDa
chr3_+_23847394 15.19 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr3_+_133502877 15.10 ENST00000466490.2
SRPRB
signal recognition particle receptor, B subunit
chr9_-_95055956 15.07 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr3_+_23847432 14.40 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr17_+_8191815 14.15 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr1_+_24019099 14.04 ENST00000443624.1
ENST00000458455.1
RPL11
ribosomal protein L11
chr10_+_12238171 13.28 ENST00000378900.2
ENST00000442050.1
CDC123
cell division cycle 123
chr3_-_194188956 13.24 ENST00000256031.4
ENST00000446356.1
ATP13A3
ATPase type 13A3
chr10_-_121296045 13.22 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr2_+_118572226 13.21 ENST00000263239.2
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chrX_+_133594168 12.86 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr11_+_60681346 11.77 ENST00000227525.3
TMEM109
transmembrane protein 109
chr5_-_142814241 11.59 ENST00000504572.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_139063372 11.08 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr3_+_23851928 11.00 ENST00000467766.1
ENST00000424381.1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr14_+_55595762 10.82 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr5_-_134735568 10.77 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr8_-_67974552 10.63 ENST00000357849.4
COPS5
COP9 signalosome subunit 5
chr11_-_118972575 10.26 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_-_21377447 9.76 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_190044480 9.57 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_327537 9.22 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr12_+_64798095 9.05 ENST00000332707.5
XPOT
exportin, tRNA
chr17_+_48823896 8.92 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr13_+_27998681 8.85 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr3_+_122785895 8.75 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr2_+_109237717 8.58 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_20251744 8.45 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr9_+_5890802 8.41 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chr17_+_56769924 8.32 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr1_-_115259337 8.27 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_+_144151520 8.17 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr3_-_79816965 7.84 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_+_114178512 7.66 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr13_-_103426112 7.58 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr3_+_179280668 7.50 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr6_+_12290586 7.42 ENST00000379375.5
EDN1
endothelin 1
chr14_+_55595960 7.40 ENST00000554715.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr4_+_83956237 7.30 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr4_+_166248775 7.23 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr5_+_95066823 7.19 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr2_+_216974020 7.17 ENST00000392132.2
ENST00000417391.1
XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr4_+_83956312 7.17 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr2_-_55237484 6.89 ENST00000394609.2
RTN4
reticulon 4
chr17_+_1936687 6.83 ENST00000570477.1
DPH1
diphthamide biosynthesis 1
chr12_-_122985067 6.75 ENST00000540586.1
ENST00000543897.1
ZCCHC8
zinc finger, CCHC domain containing 8
chr11_+_93517393 6.59 ENST00000251871.3
ENST00000530819.1
MED17
mediator complex subunit 17
chr8_-_13134045 6.42 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr15_-_101835110 6.36 ENST00000560496.1
SNRPA1
small nuclear ribonucleoprotein polypeptide A'
chr13_-_103426081 6.19 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr10_-_126849588 6.10 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr5_-_146781153 6.02 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr20_+_56964253 5.89 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr10_-_47239738 5.65 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr2_-_169104651 5.24 ENST00000355999.4
STK39
serine threonine kinase 39
chr2_+_106468204 5.14 ENST00000425756.1
ENST00000393349.2
NCK2
NCK adaptor protein 2
chr13_-_38172863 4.99 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr20_-_47804894 4.93 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
STAU1
staufen double-stranded RNA binding protein 1
chr3_-_52713729 4.82 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
PBRM1
polybromo 1
chr5_+_119867159 4.76 ENST00000505123.1
PRR16
proline rich 16
chr5_+_61602055 4.65 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr1_-_21377383 4.63 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_110933611 4.48 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr9_+_12693336 4.39 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr10_+_13203543 4.26 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chrX_-_57164058 4.09 ENST00000374906.3
SPIN2A
spindlin family, member 2A
chr7_-_32529973 4.07 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_37962018 3.93 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr7_-_20256965 3.89 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr2_+_27255806 3.78 ENST00000238788.9
ENST00000404032.3
TMEM214
transmembrane protein 214
chr11_+_7618413 3.63 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_+_41281416 3.62 ENST00000597140.1
MIA
melanoma inhibitory activity
chr2_-_160654745 3.61 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr6_+_26124373 3.55 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr1_-_109935819 3.44 ENST00000538502.1
SORT1
sortilin 1
chr10_+_48189612 3.33 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr1_-_11918988 3.21 ENST00000376468.3
NPPB
natriuretic peptide B
chr2_-_145277569 3.19 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chrX_+_105937068 3.04 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr19_+_9361606 3.04 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr4_-_48782259 2.87 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr3_+_173116225 2.78 ENST00000457714.1
NLGN1
neuroligin 1
chr6_-_26124138 2.77 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr6_-_106773491 2.73 ENST00000360666.4
ATG5
autophagy related 5
chr1_-_110933663 2.73 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr4_-_69817481 2.65 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr4_-_39979576 2.65 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr2_+_152214098 2.62 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr14_-_20801427 2.60 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr6_+_26199737 2.49 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr4_-_26492076 2.48 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr14_+_31091511 2.33 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chr17_-_47755436 2.22 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr13_+_21714913 2.11 ENST00000450573.1
ENST00000467636.1
SAP18
Sin3A-associated protein, 18kDa
chr2_-_99279928 1.97 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_-_159080806 1.94 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr1_+_186798073 1.94 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr7_+_141695671 1.92 ENST00000497673.1
ENST00000475668.2
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr7_+_141695633 1.92 ENST00000549489.2
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr20_-_16554078 1.82 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
KIF16B
kinesin family member 16B
chr11_+_105480793 1.74 ENST00000282499.5
ENST00000393127.2
ENST00000527669.1
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr16_-_21663950 1.72 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr16_-_67517716 1.71 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr4_-_70518941 1.64 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr1_-_205290865 1.61 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr16_-_21663919 1.60 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr20_+_33104199 1.55 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
DYNLRB1
dynein, light chain, roadblock-type 1
chr17_-_46671323 1.48 ENST00000239151.5
HOXB5
homeobox B5
chr6_+_25652501 1.44 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr1_+_201979645 1.30 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr13_+_50570019 1.28 ENST00000442421.1
TRIM13
tripartite motif containing 13
chr17_-_64225508 1.28 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr22_-_39268308 1.20 ENST00000407418.3
CBX6
chromobox homolog 6
chr12_+_26164645 1.08 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr9_-_21385396 1.01 ENST00000380206.2
IFNA2
interferon, alpha 2
chr19_+_40877583 0.98 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr10_-_115613828 0.96 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr13_-_46756351 0.90 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_-_46249878 0.89 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr21_-_34185944 0.85 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr4_-_155511887 0.81 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr14_-_50864006 0.59 ENST00000216378.2
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr3_+_185303962 0.59 ENST00000296257.5
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_+_39424828 0.56 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chr8_+_32579341 0.51 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr10_-_101945771 0.40 ENST00000370408.2
ENST00000407654.3
ERLIN1
ER lipid raft associated 1
chr15_+_41056255 0.36 ENST00000561160.1
ENST00000559445.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr17_+_45973516 0.24 ENST00000376741.4
SP2
Sp2 transcription factor
chr3_-_187009798 0.22 ENST00000337774.5
MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr2_+_1417228 0.20 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr19_-_51340469 0.20 ENST00000326856.4
KLK15
kallikrein-related peptidase 15
chr19_-_14889349 0.15 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr1_-_217804377 0.15 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chr20_+_56964169 0.07 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr8_+_31496809 0.06 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr18_+_10526008 0.04 ENST00000542979.1
ENST00000322897.6
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr1_-_213189168 0.02 ENST00000366962.3
ENST00000360506.2
ANGEL2
angel homolog 2 (Drosophila)
chr6_+_151561085 0.01 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_+_211342432 0.00 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
7.3 51.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
6.4 19.1 GO:0002188 translation reinitiation(GO:0002188)
6.1 18.2 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
5.5 65.6 GO:0001778 plasma membrane repair(GO:0001778)
5.1 40.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
5.0 15.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
4.3 12.9 GO:0046098 hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
3.6 10.8 GO:1901837 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
3.5 14.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
3.5 14.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
3.2 28.6 GO:0001887 selenium compound metabolic process(GO:0001887)
2.6 7.8 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
2.5 7.4 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
2.4 9.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
2.4 7.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
2.1 10.3 GO:0019348 dolichol metabolic process(GO:0019348)
1.8 18.4 GO:0007144 female meiosis I(GO:0007144)
1.7 5.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.7 5.0 GO:1990523 bone regeneration(GO:1990523)
1.7 8.3 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
1.6 4.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.6 25.1 GO:0000338 protein deneddylation(GO:0000338)
1.4 11.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.4 20.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.0 3.8 GO:0000023 maltose metabolic process(GO:0000023)
0.9 2.8 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.9 2.7 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.9 5.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.9 6.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.8 7.6 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.8 2.5 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.8 6.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.7 13.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.7 14.6 GO:0051764 actin crosslink formation(GO:0051764)
0.7 6.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7 6.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.6 16.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.5 1.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.5 6.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 13.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.4 2.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 4.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 10.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.3 3.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 3.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 3.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 8.9 GO:0009303 rRNA transcription(GO:0009303)
0.3 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 13.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 7.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 23.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 11.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 8.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.9 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 14.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 9.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 9.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 2.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 11.1 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 2.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 1.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 4.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 7.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 3.9 GO:2000816 negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.1 1.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 4.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 4.6 GO:0090307 mitotic spindle assembly(GO:0090307)
0.1 7.6 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.1 6.4 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.6 GO:0015816 glycine transport(GO:0015816)
0.1 2.0 GO:0006491 N-glycan processing(GO:0006491)
0.1 6.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.5 GO:0030728 ovulation(GO:0030728)
0.1 8.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 1.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.9 GO:0030502 negative regulation of bone mineralization(GO:0030502) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 12.9 GO:0016050 vesicle organization(GO:0016050)
0.0 7.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 4.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.5 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 8.1 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 1.5 GO:0051781 positive regulation of cell division(GO:0051781)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 51.1 GO:0044326 dendritic spine neck(GO:0044326)
3.2 9.6 GO:0005588 collagen type V trimer(GO:0005588)
2.2 15.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
1.9 7.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.8 37.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.8 10.8 GO:0001740 Barr body(GO:0001740)
1.4 7.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.4 8.3 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.1 16.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.7 80.8 GO:0005901 caveola(GO:0005901)
0.7 14.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.6 4.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.5 25.1 GO:0008180 COP9 signalosome(GO:0008180)
0.5 6.4 GO:0005686 U2 snRNP(GO:0005686)
0.5 4.3 GO:0031298 replication fork protection complex(GO:0031298)
0.5 6.1 GO:0097470 ribbon synapse(GO:0097470)
0.5 27.2 GO:0005871 kinesin complex(GO:0005871)
0.5 2.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 11.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 8.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.4 7.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 6.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 18.2 GO:0001772 immunological synapse(GO:0001772)
0.3 19.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 4.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 6.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 6.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.2 2.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 6.6 GO:0016592 mediator complex(GO:0016592)
0.2 2.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 4.8 GO:0090544 BAF-type complex(GO:0090544)
0.1 14.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 38.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 2.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 12.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 6.0 GO:0031941 filamentous actin(GO:0031941)
0.1 3.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 15.3 GO:0001650 fibrillar center(GO:0001650)
0.1 9.6 GO:0005643 nuclear pore(GO:0005643)
0.1 13.2 GO:0043679 axon terminus(GO:0043679)
0.1 14.1 GO:0000922 spindle pole(GO:0000922)
0.1 7.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 4.0 GO:0000786 nucleosome(GO:0000786)
0.1 4.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.1 GO:0043073 germ cell nucleus(GO:0043073)
0.1 9.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 22.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 8.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.6 GO:0005902 microvillus(GO:0005902)
0.1 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 26.5 GO:0005925 focal adhesion(GO:0005925)
0.1 9.0 GO:0005819 spindle(GO:0005819)
0.0 2.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 3.0 GO:0005770 late endosome(GO:0005770)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 5.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 12.9 GO:0005730 nucleolus(GO:0005730)
0.0 2.9 GO:0005938 cell cortex(GO:0005938)
0.0 1.7 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 28.6 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
7.6 22.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
6.8 40.6 GO:0042296 ISG15 transferase activity(GO:0042296)
5.0 15.1 GO:0005047 signal recognition particle binding(GO:0005047)
5.0 15.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
3.4 10.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
2.5 25.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.3 11.6 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.3 18.2 GO:0019863 IgE binding(GO:0019863)
2.0 14.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
2.0 6.0 GO:0033149 FFAT motif binding(GO:0033149)
1.6 22.9 GO:0008097 5S rRNA binding(GO:0008097)
1.5 7.4 GO:0031708 endothelin B receptor binding(GO:0031708)
1.3 51.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3 7.8 GO:0008046 axon guidance receptor activity(GO:0008046)
1.2 10.8 GO:0000182 rDNA binding(GO:0000182)
1.0 8.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.0 3.8 GO:0016160 amylase activity(GO:0016160) maltose alpha-glucosidase activity(GO:0032450)
0.9 6.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.8 2.5 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.8 6.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 22.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 7.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.7 3.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.7 14.4 GO:0000339 RNA cap binding(GO:0000339)
0.6 6.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 13.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 2.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 8.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 12.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 6.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 19.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 4.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 12.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.2 9.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 2.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 5.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 7.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 13.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 17.8 GO:0003684 damaged DNA binding(GO:0003684)
0.2 4.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 6.4 GO:0042169 SH2 domain binding(GO:0042169)
0.2 67.6 GO:0005543 phospholipid binding(GO:0005543)
0.2 7.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 7.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 4.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 41.1 GO:0003924 GTPase activity(GO:0003924)
0.1 7.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 6.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 12.8 GO:0046332 SMAD binding(GO:0046332)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 10.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 4.4 GO:0004497 monooxygenase activity(GO:0004497)
0.1 5.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 2.8 GO:0005179 hormone activity(GO:0005179)
0.1 11.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 8.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 7.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 9.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 4.1 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 4.5 GO:0016491 oxidoreductase activity(GO:0016491)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 18.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 70.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.5 26.5 PID RAS PATHWAY Regulation of Ras family activation
0.5 15.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.3 10.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 7.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 34.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 11.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 9.6 NABA COLLAGENS Genes encoding collagen proteins
0.2 19.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 8.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 9.4 PID ENDOTHELIN PATHWAY Endothelins
0.2 8.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 10.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 7.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 10.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 4.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 6.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.0 ST GAQ PATHWAY G alpha q Pathway
0.0 4.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 40.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.4 16.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.0 37.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.0 25.4 REACTOME KINESINS Genes involved in Kinesins
0.9 18.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8 28.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 7.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7 8.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.7 18.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.5 13.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 12.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 7.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 3.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 8.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 23.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 4.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 7.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 11.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 5.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 6.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 9.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 14.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 10.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 4.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 14.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 6.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 6.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 3.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 6.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis