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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for HMX3
Z-value: 1.08
Motif logo
Transcription factors associated with HMX3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HMX3
|
ENSG00000188620.9 | H6 family homeobox 3 |
Activity profile of HMX3 motif
Sorted Z-values of HMX3 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HMX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.3 | 39.9 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
| 8.0 | 40.0 | GO:1903282 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470) |
| 5.5 | 22.0 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 5.4 | 21.6 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 5.1 | 15.4 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 4.9 | 14.8 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 4.7 | 14.2 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 3.8 | 11.3 | GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) |
| 3.4 | 10.2 | GO:0007412 | axon target recognition(GO:0007412) |
| 3.0 | 15.0 | GO:0051941 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 2.7 | 10.8 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) |
| 2.7 | 8.1 | GO:0046125 | thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 2.6 | 13.2 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 2.6 | 7.8 | GO:1902997 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 2.6 | 15.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 2.5 | 7.6 | GO:1903487 | regulation of lactation(GO:1903487) |
| 2.5 | 35.3 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 2.4 | 7.3 | GO:2000532 | renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 2.4 | 7.1 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 2.3 | 6.9 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 2.3 | 11.5 | GO:0048478 | replication fork protection(GO:0048478) |
| 2.1 | 8.5 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 2.1 | 10.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 2.1 | 6.4 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 2.1 | 10.6 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 2.1 | 6.3 | GO:2001302 | cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303) |
| 2.1 | 25.1 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 2.1 | 10.4 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 2.1 | 8.2 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 2.0 | 6.0 | GO:0071048 | nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048) |
| 2.0 | 10.0 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
| 2.0 | 13.7 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 1.8 | 1.8 | GO:2000537 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 1.8 | 9.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 1.8 | 14.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.7 | 5.2 | GO:0030187 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 1.7 | 6.9 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.7 | 13.8 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 1.7 | 5.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 1.7 | 18.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 1.7 | 13.4 | GO:0015705 | iodide transport(GO:0015705) |
| 1.6 | 6.6 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 1.6 | 4.9 | GO:0071529 | cementum mineralization(GO:0071529) |
| 1.6 | 8.1 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 1.6 | 4.8 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 1.6 | 6.4 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 1.6 | 4.8 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 1.6 | 4.8 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 1.6 | 4.7 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 1.5 | 16.7 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 1.5 | 12.0 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 1.4 | 13.0 | GO:0014744 | positive regulation of muscle adaptation(GO:0014744) |
| 1.4 | 11.5 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 1.4 | 10.0 | GO:0010269 | response to selenium ion(GO:0010269) |
| 1.4 | 18.4 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 1.3 | 8.0 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 1.3 | 7.8 | GO:0052565 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 1.3 | 22.9 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 1.2 | 6.2 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 1.2 | 3.7 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866) |
| 1.2 | 4.9 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 1.2 | 6.0 | GO:0072233 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 1.1 | 4.5 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.1 | 4.5 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 1.1 | 18.9 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 1.1 | 3.3 | GO:0030309 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 1.1 | 3.2 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) |
| 1.1 | 3.2 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623) |
| 1.1 | 5.3 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 1.1 | 6.3 | GO:0018343 | protein farnesylation(GO:0018343) |
| 1.0 | 7.3 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 1.0 | 7.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 1.0 | 8.2 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 1.0 | 17.4 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 1.0 | 5.1 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 1.0 | 7.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205) |
| 1.0 | 8.0 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 1.0 | 14.1 | GO:0032196 | transposition(GO:0032196) |
| 1.0 | 1.9 | GO:0048867 | stem cell fate determination(GO:0048867) |
| 1.0 | 4.8 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 1.0 | 1.9 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.9 | 16.1 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.9 | 7.6 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
| 0.9 | 4.7 | GO:0033504 | floor plate development(GO:0033504) |
| 0.9 | 8.4 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.9 | 10.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.9 | 12.6 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.9 | 5.3 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.9 | 4.3 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.9 | 3.4 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.9 | 12.8 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.8 | 12.7 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 0.8 | 1.7 | GO:0042746 | regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746) |
| 0.8 | 10.1 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.8 | 9.2 | GO:2000582 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.8 | 2.5 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.8 | 8.2 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.8 | 20.4 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.8 | 0.8 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.8 | 4.7 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.8 | 8.5 | GO:0034372 | triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.8 | 9.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.8 | 9.8 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.7 | 3.0 | GO:2000342 | negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342) |
| 0.7 | 2.2 | GO:0002727 | natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.7 | 5.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.7 | 5.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.7 | 17.7 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.7 | 3.7 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.7 | 20.5 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.7 | 4.4 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.7 | 7.3 | GO:0019227 | neuronal action potential propagation(GO:0019227) negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) action potential propagation(GO:0098870) |
| 0.7 | 12.4 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.7 | 22.7 | GO:1901685 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.7 | 2.8 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.7 | 4.1 | GO:1903960 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) negative regulation of anion transmembrane transport(GO:1903960) |
| 0.7 | 2.7 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.7 | 2.7 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.7 | 9.6 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
| 0.7 | 3.4 | GO:0010513 | positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) |
| 0.7 | 5.3 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.6 | 5.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.6 | 5.7 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.6 | 31.7 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.6 | 1.9 | GO:0044537 | regulation of circulating fibrinogen levels(GO:0044537) |
| 0.6 | 1.9 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.6 | 3.6 | GO:0002920 | regulation of humoral immune response(GO:0002920) regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257) |
| 0.6 | 3.0 | GO:0050955 | thermoception(GO:0050955) |
| 0.6 | 2.9 | GO:0007129 | synapsis(GO:0007129) |
| 0.6 | 2.3 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.6 | 4.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.6 | 2.8 | GO:0015688 | response to mycotoxin(GO:0010046) iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.6 | 7.2 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.6 | 14.3 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
| 0.5 | 10.4 | GO:0006743 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.5 | 2.7 | GO:0010898 | positive regulation of triglyceride catabolic process(GO:0010898) |
| 0.5 | 4.9 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.5 | 2.2 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.5 | 10.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.5 | 2.1 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.5 | 4.8 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.5 | 5.7 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.5 | 5.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.5 | 5.5 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.5 | 14.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.5 | 15.5 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.5 | 1.4 | GO:0070781 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
| 0.5 | 1.4 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.5 | 3.3 | GO:0046618 | drug export(GO:0046618) |
| 0.5 | 7.5 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.5 | 7.8 | GO:0010002 | cardioblast differentiation(GO:0010002) |
| 0.5 | 2.8 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.5 | 5.0 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.4 | 1.8 | GO:0016199 | axon midline choice point recognition(GO:0016199) |
| 0.4 | 1.7 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 0.4 | 1.7 | GO:0043324 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) regulation of melanosome transport(GO:1902908) |
| 0.4 | 11.5 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.4 | 4.2 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.4 | 5.0 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.4 | 3.8 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.4 | 6.2 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.4 | 2.5 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.4 | 6.1 | GO:0045926 | negative regulation of cell growth(GO:0030308) negative regulation of growth(GO:0045926) |
| 0.4 | 4.5 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.4 | 2.4 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.4 | 1.2 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.4 | 2.4 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.4 | 10.3 | GO:0097503 | sialylation(GO:0097503) |
| 0.4 | 1.6 | GO:0060748 | tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) |
| 0.4 | 4.6 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.4 | 0.8 | GO:1903059 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.4 | 4.2 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.4 | 1.1 | GO:0019605 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.4 | 4.9 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.4 | 58.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.4 | 7.2 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.4 | 3.5 | GO:0071280 | cellular response to copper ion(GO:0071280) |
| 0.3 | 3.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 1.3 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
| 0.3 | 4.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.3 | 0.9 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.3 | 8.7 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.3 | 6.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.3 | 11.8 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.3 | 8.9 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.3 | 0.9 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.3 | 1.8 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.3 | 3.5 | GO:0034505 | tooth mineralization(GO:0034505) |
| 0.3 | 11.0 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.3 | 2.2 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.3 | 11.7 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.3 | 5.3 | GO:0051923 | sulfation(GO:0051923) |
| 0.3 | 1.6 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.3 | 2.2 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 0.3 | 1.1 | GO:0097283 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.3 | 33.4 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.3 | 7.1 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.3 | 7.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.2 | 12.4 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.2 | 18.1 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.2 | 2.1 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.2 | 2.8 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.2 | 2.8 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.2 | 7.4 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.2 | 4.6 | GO:0006833 | water transport(GO:0006833) |
| 0.2 | 8.9 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.2 | 0.6 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.2 | 6.2 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.2 | 7.3 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
| 0.2 | 11.3 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.2 | 1.0 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.2 | 3.9 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.2 | 7.3 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 2.8 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.2 | 1.8 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 6.7 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.2 | 6.0 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.2 | 1.4 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.2 | 10.1 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.2 | 4.5 | GO:0010762 | regulation of fibroblast migration(GO:0010762) |
| 0.2 | 3.8 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.2 | 0.9 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.2 | 3.6 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.2 | 4.1 | GO:0090083 | regulation of inclusion body assembly(GO:0090083) |
| 0.2 | 1.7 | GO:0048016 | inositol phosphate-mediated signaling(GO:0048016) |
| 0.2 | 6.8 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.2 | 23.2 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.2 | 2.8 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 1.8 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.2 | 4.1 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 3.7 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.2 | 2.0 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.2 | 5.6 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.2 | 5.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.2 | 2.3 | GO:0050974 | detection of mechanical stimulus involved in sensory perception(GO:0050974) |
| 0.2 | 5.1 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.1 | 3.0 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.1 | 2.5 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 1.5 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
| 0.1 | 6.0 | GO:0070206 | protein trimerization(GO:0070206) |
| 0.1 | 2.8 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 8.2 | GO:0006305 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.1 | 5.6 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 4.0 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.1 | 1.7 | GO:0036344 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.1 | 5.4 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 3.9 | GO:0050776 | regulation of immune response(GO:0050776) |
| 0.1 | 2.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 4.4 | GO:0045843 | negative regulation of striated muscle tissue development(GO:0045843) |
| 0.1 | 1.3 | GO:0007350 | blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
| 0.1 | 2.4 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.1 | 5.5 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.1 | 1.0 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 10.1 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 7.5 | GO:0030101 | natural killer cell activation(GO:0030101) |
| 0.1 | 0.1 | GO:0035992 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.1 | 5.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 6.3 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.1 | 0.1 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.1 | 2.6 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 2.2 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.1 | 1.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.1 | 1.4 | GO:0060828 | regulation of canonical Wnt signaling pathway(GO:0060828) |
| 0.1 | 5.5 | GO:0044782 | cilium organization(GO:0044782) |
| 0.1 | 1.4 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.1 | 0.8 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.1 | 2.8 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.8 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 5.1 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011) |
| 0.1 | 0.6 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.1 | 0.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 2.6 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.1 | 14.8 | GO:0045666 | positive regulation of neuron differentiation(GO:0045666) |
| 0.1 | 8.9 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.1 | 0.8 | GO:0045087 | innate immune response(GO:0045087) |
| 0.1 | 8.6 | GO:1902807 | negative regulation of cell cycle G1/S phase transition(GO:1902807) |
| 0.1 | 2.1 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.1 | 6.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.1 | 1.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 1.2 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 1.4 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.1 | 3.4 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
| 0.1 | 1.1 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 3.4 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) |
| 0.1 | 0.7 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 7.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 2.4 | GO:0007595 | lactation(GO:0007595) |
| 0.1 | 0.7 | GO:0030193 | regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046) |
| 0.1 | 3.9 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.1 | 0.9 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 2.9 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.0 | 1.2 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 2.1 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 3.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 2.7 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.0 | 0.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 7.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 1.8 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.0 | 1.8 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.4 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 3.7 | GO:0007265 | Ras protein signal transduction(GO:0007265) |
| 0.0 | 1.8 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.4 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.0 | 0.9 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 4.6 | GO:0007411 | axon guidance(GO:0007411) |
| 0.0 | 3.2 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
| 0.0 | 1.0 | GO:0008217 | regulation of blood pressure(GO:0008217) |
| 0.0 | 0.1 | GO:0071386 | cellular response to corticosterone stimulus(GO:0071386) |
| 0.0 | 1.7 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.0 | 1.3 | GO:0035264 | multicellular organism growth(GO:0035264) |
| 0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.4 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.0 | 0.2 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.2 | GO:0050890 | cognition(GO:0050890) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 15.3 | GO:0031417 | NatC complex(GO:0031417) |
| 3.3 | 9.8 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 2.3 | 11.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 2.2 | 11.0 | GO:0000801 | central element(GO:0000801) |
| 2.0 | 6.0 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 1.8 | 25.1 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 1.7 | 3.4 | GO:0033150 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
| 1.6 | 6.3 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 1.4 | 44.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 1.4 | 8.6 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 1.3 | 22.0 | GO:0043194 | axon initial segment(GO:0043194) |
| 1.2 | 3.7 | GO:0098536 | deuterosome(GO:0098536) |
| 1.2 | 8.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 1.0 | 6.2 | GO:0032807 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 1.0 | 2.1 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 1.0 | 6.1 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 1.0 | 14.0 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.9 | 21.0 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.8 | 10.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.8 | 7.4 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.8 | 4.9 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.8 | 4.8 | GO:1990037 | Lewy body core(GO:1990037) |