Project

GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for HOXA10_HOXB9

Z-value: 0.07

Motif logo

logo of logo of

Transcription factors associated with HOXA10_HOXB9

Gene Symbol Gene ID Gene Info
HOXA10
ENSG00000253293.3 homeobox A10
HOXB9
ENSG00000170689.8 homeobox B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA10hg19_v2_chr7_-_27213893_27213954-0.211.6e-03Click!
HOXB9hg19_v2_chr17_-_46703826_46703845-0.136.5e-02Click!

Activity profile of HOXA10_HOXB9 motif

Sorted Z-values of HOXA10_HOXB9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_84630645 8.47 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr15_-_55541227 8.33 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr10_-_73848086 7.61 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_73848531 7.11 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_-_18480260 6.61 ENST00000454909.2
SATB1
SATB homeobox 1
chr8_-_81083890 6.15 ENST00000518937.1
TPD52
tumor protein D52
chr4_-_71532339 5.87 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_51259292 5.80 ENST00000401669.2
NRXN1
neurexin 1
chr4_+_71248795 5.74 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr2_-_51259229 5.74 ENST00000405472.3
NRXN1
neurexin 1
chr9_+_2029019 5.55 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_60097524 5.30 ENST00000342503.4
RTN1
reticulon 1
chr14_-_60097297 5.26 ENST00000395090.1
RTN1
reticulon 1
chr12_+_54892550 5.08 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr1_-_160231451 4.82 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr4_-_57522598 4.61 ENST00000553379.2
HOPX
HOP homeobox
chr6_+_158733692 4.61 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr11_-_104972158 4.43 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_-_57522673 4.31 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOPX
HOP homeobox
chr12_+_25205568 3.95 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr18_-_5396271 3.93 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr4_+_70894130 3.89 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr10_+_94451574 3.83 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr6_+_32812568 3.82 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr12_-_90049878 3.69 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr5_+_67586465 3.67 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_90049828 3.63 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_57547870 3.62 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX
HOP homeobox
chr4_+_70861647 3.59 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr6_+_6588316 3.46 ENST00000379953.2
LY86
lymphocyte antigen 86
chr1_+_12524965 3.38 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr6_+_12958137 3.33 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr4_-_100356551 3.18 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_-_104905840 3.15 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr9_+_137979506 3.10 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr4_+_70916119 3.03 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr4_+_68424434 2.96 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr12_+_25205666 2.89 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr5_-_88119580 2.86 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr12_+_25205446 2.85 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr17_-_10452929 2.78 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr22_-_23922410 2.48 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr12_-_118628350 2.46 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_-_58295712 2.30 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_90198535 2.19 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr5_-_130500922 2.18 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr17_-_29624343 2.18 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr11_-_102576537 2.13 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr9_+_134065506 2.09 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr16_-_15180257 2.04 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_-_152386732 2.00 ENST00000271835.3
CRNN
cornulin
chr11_-_3400442 1.97 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr17_+_48823975 1.97 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr11_-_3400330 1.91 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
ZNF195
zinc finger protein 195
chr10_-_103599591 1.81 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr1_-_226926864 1.77 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr3_-_50375657 1.75 ENST00000395126.3
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr8_-_81083731 1.72 ENST00000379096.5
TPD52
tumor protein D52
chr3_-_58196688 1.70 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr9_-_95087838 1.68 ENST00000442668.2
ENST00000421075.2
ENST00000536624.1
NOL8
nucleolar protein 8
chr19_-_29704448 1.67 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr21_+_34398153 1.62 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
OLIG2
oligodendrocyte lineage transcription factor 2
chr5_+_43121698 1.59 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131
zinc finger protein 131
chr18_-_53069419 1.58 ENST00000570177.2
TCF4
transcription factor 4
chr11_+_10471836 1.57 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr8_+_1993152 1.57 ENST00000262113.4
MYOM2
myomesin 2
chr1_+_73771844 1.56 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr8_+_95565947 1.55 ENST00000523011.1
RP11-267M23.4
RP11-267M23.4
chr5_+_140261703 1.54 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr12_-_54071181 1.54 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr8_+_1993173 1.53 ENST00000523438.1
MYOM2
myomesin 2
chr6_+_83903061 1.52 ENST00000369724.4
ENST00000539997.1
RWDD2A
RWD domain containing 2A
chr9_+_91933726 1.51 ENST00000534113.2
SECISBP2
SECIS binding protein 2
chrX_-_122756660 1.51 ENST00000441692.1
THOC2
THO complex 2
chr1_+_154401791 1.49 ENST00000476006.1
IL6R
interleukin 6 receptor
chr20_-_8000426 1.47 ENST00000527925.1
ENST00000246024.2
TMX4
thioredoxin-related transmembrane protein 4
chr4_-_140222358 1.38 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr14_-_25479811 1.35 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr1_+_153003671 1.34 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr7_+_24323782 1.34 ENST00000242152.2
ENST00000407573.1
NPY
neuropeptide Y
chr4_+_71337834 1.33 ENST00000304887.5
MUC7
mucin 7, secreted
chr10_+_96698406 1.33 ENST00000260682.6
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr8_-_95220775 1.32 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr13_-_79979919 1.30 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr2_+_208423840 1.29 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr4_+_71226468 1.29 ENST00000226460.4
SMR3A
submaxillary gland androgen regulated protein 3A
chr6_+_42584847 1.28 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr15_-_22448819 1.26 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr12_-_81992111 1.25 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr13_-_79979952 1.25 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr1_+_229440129 1.25 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr2_-_40657397 1.24 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_90192768 1.23 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr4_-_90759440 1.23 ENST00000336904.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_135962876 1.22 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr13_-_47012325 1.21 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr18_-_52989217 1.18 ENST00000570287.2
TCF4
transcription factor 4
chr2_+_173686303 1.16 ENST00000397087.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_140165876 1.16 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr20_-_7921090 1.14 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chrX_+_105937068 1.13 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr18_-_52989525 1.10 ENST00000457482.3
TCF4
transcription factor 4
chr14_+_53173910 1.09 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr9_-_179018 1.07 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr14_+_53173890 1.07 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr15_-_58571445 1.06 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_-_21663919 1.06 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr10_+_133747955 1.04 ENST00000455566.1
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr9_+_125703282 1.02 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr22_-_23922448 0.99 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr3_+_169629354 0.99 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr4_+_113568207 0.98 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr7_-_142232071 0.97 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr2_-_176046391 0.97 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_+_157828152 0.93 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr4_-_87281224 0.92 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr12_-_57146095 0.91 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr8_+_128426535 0.90 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr9_+_70856397 0.89 ENST00000360171.6
CBWD3
COBW domain containing 3
chr8_+_132952112 0.86 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr1_+_74701062 0.86 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr6_+_26156551 0.85 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr5_-_176433693 0.85 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr1_+_22379179 0.84 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr20_-_34287103 0.84 ENST00000374085.1
ENST00000419569.1
NFS1
NFS1 cysteine desulfurase
chr11_-_118972575 0.83 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr19_-_3500635 0.83 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr19_+_19626531 0.83 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr4_-_76957214 0.82 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chrX_-_110655306 0.82 ENST00000371993.2
DCX
doublecortin
chr1_-_39339777 0.82 ENST00000397572.2
MYCBP
MYC binding protein
chr5_-_20575959 0.81 ENST00000507958.1
CDH18
cadherin 18, type 2
chr19_+_21265028 0.81 ENST00000291770.7
ZNF714
zinc finger protein 714
chr10_+_88428206 0.81 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr3_-_123710199 0.79 ENST00000184183.4
ROPN1
rhophilin associated tail protein 1
chr5_+_135496675 0.78 ENST00000507637.1
SMAD5
SMAD family member 5
chr9_+_42671887 0.77 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr3_-_172241250 0.77 ENST00000420541.2
ENST00000241261.2
TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
chr2_-_152382500 0.74 ENST00000434685.1
NEB
nebulin
chr13_-_103719196 0.72 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr11_-_13517565 0.72 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr8_-_8318847 0.72 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr14_-_106453155 0.72 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr6_-_137539651 0.72 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr7_+_57509877 0.71 ENST00000420713.1
ZNF716
zinc finger protein 716
chr4_+_71263599 0.69 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr1_-_7913089 0.69 ENST00000361696.5
UTS2
urotensin 2
chr17_-_10560619 0.69 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr5_+_140514782 0.67 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr17_-_46806540 0.67 ENST00000290295.7
HOXB13
homeobox B13
chr9_-_69262509 0.63 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6
COBW domain containing 6
chr1_-_54355430 0.63 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr22_-_22292934 0.62 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chrX_-_15619076 0.61 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr16_-_21663950 0.60 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr12_-_71551868 0.59 ENST00000247829.3
TSPAN8
tetraspanin 8
chr11_-_104827425 0.58 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_31456874 0.57 ENST00000541626.1
EHD3
EH-domain containing 3
chr12_-_8765446 0.57 ENST00000537228.1
ENST00000229335.6
AICDA
activation-induced cytidine deaminase
chr16_+_25123041 0.55 ENST00000399069.3
ENST00000380966.4
LCMT1
leucine carboxyl methyltransferase 1
chr11_+_61717336 0.54 ENST00000378042.3
BEST1
bestrophin 1
chr19_+_1440838 0.52 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr15_+_75639296 0.52 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr18_+_19192228 0.52 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr14_+_79745746 0.52 ENST00000281127.7
NRXN3
neurexin 3
chr13_-_46626847 0.51 ENST00000242848.4
ENST00000282007.3
ZC3H13
zinc finger CCCH-type containing 13
chr20_-_50384864 0.50 ENST00000311637.5
ENST00000402822.1
ATP9A
ATPase, class II, type 9A
chr19_+_12175504 0.49 ENST00000439326.3
ZNF844
zinc finger protein 844
chr2_-_154335300 0.49 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chrX_-_73072534 0.49 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr2_+_208423891 0.48 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr15_+_67835517 0.46 ENST00000395476.2
MAP2K5
mitogen-activated protein kinase kinase 5
chr11_+_61717279 0.46 ENST00000378043.4
BEST1
bestrophin 1
chr6_-_109804412 0.45 ENST00000230122.3
ZBTB24
zinc finger and BTB domain containing 24
chr18_+_42260861 0.45 ENST00000282030.5
SETBP1
SET binding protein 1
chr12_+_57810198 0.44 ENST00000598001.1
AC126614.1
HCG1818482; Uncharacterized protein
chr2_+_27440229 0.43 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr9_+_82187630 0.42 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr22_+_24407642 0.42 ENST00000454754.1
ENST00000263119.5
CABIN1
calcineurin binding protein 1
chr2_-_209010874 0.42 ENST00000260988.4
CRYGB
crystallin, gamma B
chr6_-_8102714 0.42 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr1_+_67773044 0.41 ENST00000262345.1
ENST00000371000.1
IL12RB2
interleukin 12 receptor, beta 2
chr10_+_91152303 0.41 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr2_+_161993412 0.41 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr9_+_82187487 0.40 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_+_76452097 0.38 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_143767881 0.37 ENST00000419275.1
PPIAL4G
peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr14_-_51027838 0.36 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_220263096 0.36 ENST00000463953.1
ENST00000354807.3
ENST00000414869.2
ENST00000498237.2
ENST00000498791.2
ENST00000544404.1
ENST00000480959.2
ENST00000322067.7
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr17_-_39553844 0.35 ENST00000251645.2
KRT31
keratin 31
chr9_-_104145795 0.34 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_+_151739131 0.34 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr1_+_241695670 0.33 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr9_+_103947311 0.33 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr1_+_117963209 0.32 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr11_+_120973375 0.32 ENST00000264037.2
TECTA
tectorin alpha
chr2_+_234668894 0.31 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
UGT1A8
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr22_-_22337146 0.28 ENST00000398793.2
TOP3B
topoisomerase (DNA) III beta
chr2_+_220144052 0.28 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr19_+_48497962 0.28 ENST00000596043.1
ENST00000597519.1
ELSPBP1
epididymal sperm binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA10_HOXB9

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.7 8.5 GO:0097338 response to clozapine(GO:0097338)
1.5 7.3 GO:1990034 calcium ion export from cell(GO:1990034)
1.4 11.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.4 8.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.3 3.8 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
1.3 5.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
1.1 3.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
1.0 3.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.7 2.9 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.7 14.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7 1.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.6 3.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.6 6.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 12.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.5 1.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.5 1.5 GO:0002384 hepatic immune response(GO:0002384)
0.4 3.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 3.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.3 3.6 GO:0046541 saliva secretion(GO:0046541)
0.3 0.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 1.8 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.3 2.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 0.8 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.3 2.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 1.6 GO:0006196 AMP catabolic process(GO:0006196)
0.3 1.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.3 GO:0071233 cellular response to leucine(GO:0071233)
0.3 2.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 1.8 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.2 1.2 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.2 0.7 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.2 2.8 GO:0001778 plasma membrane repair(GO:0001778)
0.2 3.7 GO:0051531 NFAT protein import into nucleus(GO:0051531) positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.2 0.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 1.7 GO:1902570 protein localization to nucleolus(GO:1902570)
0.2 0.6 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.3 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.2 1.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.2 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.7 GO:0042320 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 6.9 GO:0050832 defense response to fungus(GO:0050832)
0.2 1.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 1.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 1.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 1.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.1 GO:0035799 ureter maturation(GO:0035799)
0.1 0.5 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.7 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.8 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 4.6 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 2.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1 0.3 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.1 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 2.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.9 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 1.0 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 9.9 GO:0007338 single fertilization(GO:0007338)
0.1 4.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.6 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 4.6 GO:0007286 spermatid development(GO:0007286)
0.0 2.2 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.0 5.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 3.8 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.3 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.9 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:2000774 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of cellular senescence(GO:2000774)
0.0 3.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 2.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.8 GO:0001764 neuron migration(GO:0001764)
0.0 2.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.3 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 2.0 GO:0009408 response to heat(GO:0009408)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.7 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.6 GO:0097179 protease inhibitor complex(GO:0097179)
0.9 2.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.9 3.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.7 2.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.7 8.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 3.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.4 1.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.4 8.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 5.1 GO:0031209 SCAR complex(GO:0031209)
0.4 2.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 7.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 1.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 5.6 GO:0071564 npBAF complex(GO:0071564)
0.2 3.9 GO:0033270 paranode region of axon(GO:0033270)
0.2 1.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.6 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 7.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 1.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 3.8 GO:0032982 myosin filament(GO:0032982)
0.2 0.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 2.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 9.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 11.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0000322 storage vacuole(GO:0000322)
0.1 4.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.2 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1 0.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.5 GO:0071010 prespliceosome(GO:0071010)
0.1 11.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 8.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.3 GO:0005929 cilium(GO:0005929)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 1.8 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0046848 hydroxyapatite binding(GO:0046848)
0.9 4.3 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.8 12.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.7 2.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.6 8.2 GO:0050700 CARD domain binding(GO:0050700)
0.5 13.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 8.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 1.5 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.5 3.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.5 3.7 GO:0043559 insulin binding(GO:0043559)
0.4 1.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 8.3 GO:0071837 HMG box domain binding(GO:0071837)
0.3 1.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 8.3 GO:0031489 myosin V binding(GO:0031489)
0.3 3.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 0.8 GO:0032427 GBD domain binding(GO:0032427)
0.3 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 1.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 1.3 GO:0070728 leucine binding(GO:0070728)
0.3 7.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 1.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 1.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.8 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 2.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 2.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 1.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 3.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.5 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 2.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 4.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 3.5 GO:0030552 cAMP binding(GO:0030552)
0.1 1.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 4.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 2.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.4 GO:0008252 nucleotidase activity(GO:0008252)
0.0 7.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 4.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.0 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 3.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 3.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 3.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 14.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 12.1 PID IL3 PATHWAY IL3-mediated signaling events
0.2 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 12.9 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.5 ST STAT3 PATHWAY STAT3 Pathway
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 6.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 4.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 3.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 8.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 10.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 3.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 7.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 7.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 6.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 6.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 2.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 3.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription