Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for HOXA5
Z-value: 0.06
Motif logo
Transcription factors associated with HOXA5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXA5 | hg19_v2_chr7_-_27183263_27183287 | -0.18 | 7.3e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXA5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 19.5 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
| 1.2 | 10.7 | GO:0014052 | regulation of gamma-aminobutyric acid secretion(GO:0014052) |
| 2.1 | 8.4 | GO:0001971 | negative regulation of activation of membrane attack complex(GO:0001971) |
| 2.7 | 8.2 | GO:2000705 | dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705) |
| 0.0 | 7.6 | GO:0034605 | cellular response to heat(GO:0034605) |
| 2.5 | 7.4 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 1.1 | 5.3 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.3 | 4.7 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.5 | 4.6 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 0.0 | 4.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 27.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.6 | 10.7 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.6 | 8.2 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.6 | 7.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 5.8 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.3 | 5.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 1.2 | 4.6 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.0 | 4.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 3.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 3.3 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 19.5 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.0 | 9.6 | GO:0019901 | protein kinase binding(GO:0019901) |
| 0.2 | 8.4 | GO:0001848 | complement binding(GO:0001848) |
| 1.8 | 7.4 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.0 | 6.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.3 | 5.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 5.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.4 | 4.7 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 4.6 | GO:0019894 | kinesin binding(GO:0019894) |
| 1.4 | 4.3 | GO:0046921 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 19.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 8.8 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 6.9 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 4.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 3.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 2.4 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 2.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.6 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 1.4 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 21.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 5.3 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 4.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 4.3 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.0 | 3.5 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 3.4 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.1 | 3.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.0 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 2.4 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |