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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for HOXA9

Z-value: 0.07

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Transcription factors associated with HOXA9

Gene Symbol Gene ID Gene Info
HOXA9
ENSG00000078399.11 homeobox A9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA9hg19_v2_chr7_-_27205136_272051640.045.2e-01Click!

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_13835147 17.32 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr3_+_158787041 17.11 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chrX_+_103031758 11.69 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chrX_-_13835461 10.40 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chrX_+_114827818 10.20 ENST00000420625.2
PLS3
plastin 3
chr4_-_176733897 9.64 ENST00000393658.2
GPM6A
glycoprotein M6A
chr3_-_58613323 9.41 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr2_+_201170596 9.24 ENST00000439084.1
ENST00000409718.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr16_+_56691606 8.28 ENST00000334350.6
MT1F
metallothionein 1F
chr2_+_20646824 8.15 ENST00000272233.4
RHOB
ras homolog family member B
chr17_-_29624343 7.86 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr16_+_56691911 7.84 ENST00000568475.1
MT1F
metallothionein 1F
chr2_-_224467093 7.77 ENST00000305409.2
SCG2
secretogranin II
chr16_+_56691838 7.74 ENST00000394501.2
MT1F
metallothionein 1F
chr5_-_146833485 6.56 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr16_+_15596123 6.50 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chrX_-_92928557 6.20 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr3_-_195310802 5.46 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr7_+_16793160 5.39 ENST00000262067.4
TSPAN13
tetraspanin 13
chr4_-_102267953 5.22 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_50575292 5.21 ENST00000371821.1
ENST00000371819.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr12_-_56123444 4.90 ENST00000546457.1
ENST00000549117.1
CD63
CD63 molecule
chr11_+_27062502 4.84 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_+_113970772 4.83 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr4_-_186732048 4.63 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr17_-_66951474 4.51 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr7_+_69064300 4.49 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr5_+_141488070 4.47 ENST00000253814.4
NDFIP1
Nedd4 family interacting protein 1
chr10_-_101190202 3.96 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chr4_-_99578776 3.94 ENST00000515287.1
TSPAN5
tetraspanin 5
chr12_-_56122761 3.89 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63
CD63 molecule
chr15_-_49338748 3.88 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr5_-_146833222 3.79 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr22_-_36236265 3.77 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_+_71820057 3.77 ENST00000539225.1
TJP2
tight junction protein 2
chr3_-_47622282 3.66 ENST00000383738.2
ENST00000264723.4
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr11_+_27062860 3.64 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_-_88427568 3.64 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr9_+_71819927 3.64 ENST00000535702.1
TJP2
tight junction protein 2
chr9_+_470288 3.56 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr3_+_148545586 3.52 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr3_+_35721106 3.51 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr5_-_94417339 3.46 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chrX_-_72434628 3.45 ENST00000536638.1
ENST00000373517.3
NAP1L2
nucleosome assembly protein 1-like 2
chr6_+_158733692 3.42 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr13_+_53602894 3.32 ENST00000219022.2
OLFM4
olfactomedin 4
chr4_+_154074217 3.26 ENST00000437508.2
TRIM2
tripartite motif containing 2
chr8_-_18666360 3.24 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr7_+_153584166 3.18 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr9_-_21305312 3.05 ENST00000259555.4
IFNA5
interferon, alpha 5
chr11_+_27062272 3.03 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chrX_+_65384182 3.03 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr21_-_30257669 2.88 ENST00000303775.5
ENST00000351429.3
N6AMT1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr10_+_91092241 2.86 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr16_-_18462221 2.85 ENST00000528301.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr18_-_24443151 2.81 ENST00000440832.3
AQP4
aquaporin 4
chr9_-_21187598 2.76 ENST00000421715.1
IFNA4
interferon, alpha 4
chr19_-_18314836 2.76 ENST00000464076.3
ENST00000222256.4
RAB3A
RAB3A, member RAS oncogene family
chr1_+_50574585 2.73 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr2_+_136343820 2.72 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr2_-_106054952 2.66 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr11_-_35441524 2.64 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr22_-_18111499 2.63 ENST00000413576.1
ENST00000399796.2
ENST00000399798.2
ENST00000253413.5
ATP6V1E1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
chr15_+_45315302 2.58 ENST00000267814.9
SORD
sorbitol dehydrogenase
chr6_+_126240442 2.51 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr13_+_98794810 2.49 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_35440796 2.47 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chrX_+_65382433 2.41 ENST00000374727.3
HEPH
hephaestin
chr4_-_69536346 2.38 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr12_+_21207503 2.35 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr21_-_35014027 2.34 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr1_-_193075180 2.33 ENST00000367440.3
GLRX2
glutaredoxin 2
chr2_+_74056147 2.32 ENST00000394070.2
ENST00000536064.1
STAMBP
STAM binding protein
chr3_-_9885626 2.30 ENST00000424438.1
ENST00000433555.1
ENST00000427174.1
ENST00000418713.1
ENST00000433535.2
ENST00000383820.5
ENST00000433972.1
RPUSD3
RNA pseudouridylate synthase domain containing 3
chr4_-_110723134 2.30 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_+_138721850 2.27 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr19_-_14945933 2.27 ENST00000322301.3
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr2_+_74056066 2.24 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP
STAM binding protein
chr9_-_21202204 2.22 ENST00000239347.3
IFNA7
interferon, alpha 7
chr4_-_74964904 2.15 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chrX_+_65384052 2.08 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr17_-_8113542 2.08 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr18_+_34124507 2.06 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr11_+_57529234 2.03 ENST00000360682.6
ENST00000361796.4
ENST00000529526.1
ENST00000426142.2
ENST00000399050.4
ENST00000361391.6
ENST00000361332.4
ENST00000532463.1
ENST00000529986.1
ENST00000358694.6
ENST00000532787.1
ENST00000533667.1
ENST00000532649.1
ENST00000528621.1
ENST00000530748.1
ENST00000428599.2
ENST00000527467.1
ENST00000528232.1
ENST00000531014.1
ENST00000526772.1
ENST00000529873.1
ENST00000525902.1
ENST00000532844.1
ENST00000526357.1
ENST00000530094.1
ENST00000415361.2
ENST00000532245.1
ENST00000534579.1
ENST00000526938.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr7_+_55177416 2.00 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr19_+_8455077 1.96 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr4_-_99578789 1.95 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr5_+_159436120 1.95 ENST00000522793.1
ENST00000231238.5
TTC1
tetratricopeptide repeat domain 1
chr3_-_197686847 1.94 ENST00000265239.6
IQCG
IQ motif containing G
chr14_-_31926701 1.93 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr16_+_16434185 1.89 ENST00000524823.2
AC138969.4
Protein PKD1P1
chr1_+_104615595 1.88 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr9_-_95640218 1.88 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr11_-_2182388 1.87 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr22_-_30642782 1.85 ENST00000249075.3
LIF
leukemia inhibitory factor
chr1_-_23886285 1.80 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr3_-_48130707 1.79 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr12_-_71148413 1.75 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr14_+_78870030 1.73 ENST00000553631.1
ENST00000554719.1
NRXN3
neurexin 3
chr3_+_149192475 1.72 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chrX_+_41583408 1.72 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr11_-_76155700 1.72 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr21_+_37507210 1.70 ENST00000290354.5
CBR3
carbonyl reductase 3
chr10_-_96829246 1.70 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr17_+_58755184 1.69 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr19_-_47975417 1.64 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr5_+_140213815 1.62 ENST00000525929.1
ENST00000378125.3
PCDHA7
protocadherin alpha 7
chr14_+_78174414 1.62 ENST00000557342.1
ENST00000238688.5
ENST00000557623.1
ENST00000557431.1
ENST00000556831.1
ENST00000556375.1
ENST00000553981.1
SLIRP
SRA stem-loop interacting RNA binding protein
chr2_-_242626127 1.59 ENST00000445261.1
DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr2_+_143635067 1.59 ENST00000264170.4
KYNU
kynureninase
chr3_+_87276407 1.58 ENST00000471660.1
ENST00000263780.4
ENST00000494980.1
CHMP2B
charged multivesicular body protein 2B
chr3_-_183273477 1.58 ENST00000341319.3
KLHL6
kelch-like family member 6
chr7_-_99277610 1.57 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr10_-_72141330 1.54 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr15_+_93749295 1.50 ENST00000599897.1
AC112693.2
AC112693.2
chr11_-_35441597 1.49 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr15_+_66797627 1.49 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr2_-_225811747 1.47 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr4_-_76439483 1.45 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr2_+_143635222 1.43 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr9_+_21409146 1.42 ENST00000380205.1
IFNA8
interferon, alpha 8
chr18_-_10701979 1.40 ENST00000538948.1
ENST00000285141.4
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr1_-_235292250 1.36 ENST00000366607.4
TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr6_+_111195973 1.34 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr12_-_10978957 1.34 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr17_+_73257742 1.34 ENST00000579761.1
ENST00000245539.6
MRPS7
mitochondrial ribosomal protein S7
chr2_-_154335300 1.29 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr18_+_32558208 1.29 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_-_28969517 1.28 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr11_-_76155618 1.25 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr15_+_66797455 1.24 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr17_+_73257945 1.24 ENST00000579002.1
MRPS7
mitochondrial ribosomal protein S7
chr9_-_21228221 1.23 ENST00000413767.2
IFNA17
interferon, alpha 17
chr4_-_110723194 1.23 ENST00000394635.3
CFI
complement factor I
chr2_+_232063260 1.22 ENST00000349938.4
ARMC9
armadillo repeat containing 9
chr17_-_48943706 1.22 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr14_+_61201445 1.21 ENST00000261245.4
ENST00000539616.2
MNAT1
MNAT CDK-activating kinase assembly factor 1
chr10_+_18689637 1.19 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_88876058 1.19 ENST00000369501.2
CNR1
cannabinoid receptor 1 (brain)
chr8_-_97247759 1.16 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr7_-_14880892 1.16 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr5_-_150138061 1.14 ENST00000521533.1
ENST00000424236.1
DCTN4
dynactin 4 (p62)
chr3_+_138340067 1.11 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr4_-_72649763 1.09 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr16_-_20338748 1.07 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr1_+_44584522 1.06 ENST00000372299.3
KLF17
Kruppel-like factor 17
chr17_-_56494908 1.05 ENST00000577716.1
RNF43
ring finger protein 43
chr9_-_21368075 1.05 ENST00000449498.1
IFNA13
interferon, alpha 13
chr2_+_138722028 1.04 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr11_-_108464465 1.04 ENST00000525344.1
EXPH5
exophilin 5
chr11_+_20385231 1.03 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr19_-_10420459 1.01 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr6_+_25279651 0.99 ENST00000329474.6
LRRC16A
leucine rich repeat containing 16A
chr13_-_47471155 0.99 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr2_+_219646462 0.99 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr6_-_30710510 0.98 ENST00000376389.3
FLOT1
flotillin 1
chr16_-_20339123 0.97 ENST00000381360.5
GP2
glycoprotein 2 (zymogen granule membrane)
chrX_-_77150985 0.96 ENST00000358075.6
MAGT1
magnesium transporter 1
chr6_+_57037089 0.96 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr20_+_43211149 0.95 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr7_-_83824169 0.94 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr9_-_86571628 0.93 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr11_+_20385327 0.90 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr6_+_63921351 0.90 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr11_+_61891445 0.89 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr2_-_69098566 0.89 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr16_+_29690358 0.88 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr21_+_44313375 0.88 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr9_-_21207142 0.87 ENST00000357374.2
IFNA10
interferon, alpha 10
chr12_-_121477039 0.85 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_118796910 0.83 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr12_-_121476959 0.82 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr15_+_67418047 0.82 ENST00000540846.2
SMAD3
SMAD family member 3
chr17_-_37934466 0.81 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr11_+_59522837 0.81 ENST00000437946.2
STX3
syntaxin 3
chr2_+_32502952 0.81 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr12_-_56615693 0.80 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41
ring finger protein 41
chr6_-_138539627 0.80 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr4_-_159644507 0.79 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr3_-_196911002 0.79 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr6_+_99282570 0.78 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr6_+_160327974 0.77 ENST00000252660.4
MAS1
MAS1 oncogene
chr15_+_79165112 0.77 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr7_+_141811539 0.76 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr4_-_76944621 0.76 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr3_+_186353756 0.75 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr5_-_177210399 0.75 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr19_+_9296279 0.75 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr18_-_72265035 0.74 ENST00000585279.1
ENST00000580048.1
LINC00909
long intergenic non-protein coding RNA 909
chr7_-_99332719 0.73 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr7_+_86781847 0.73 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
DMTF1
cyclin D binding myb-like transcription factor 1
chr4_-_74088800 0.72 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr12_+_15475331 0.70 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr5_+_34915444 0.69 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr2_+_64069459 0.68 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr14_-_25479811 0.67 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_-_36661826 0.60 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr9_+_117373486 0.60 ENST00000288502.4
ENST00000374049.4
C9orf91
chromosome 9 open reading frame 91
chr1_-_113498616 0.60 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr3_+_185300391 0.59 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 27.7 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.8 5.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.7 5.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
1.6 4.8 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.5 3.0 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.5 4.5 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
1.3 4.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
1.3 6.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.2 3.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.2 11.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.1 4.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 20.5 GO:0051764 actin crosslink formation(GO:0051764)
0.9 2.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.9 2.6 GO:0006059 hexitol metabolic process(GO:0006059)
0.8 6.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.8 22.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.7 7.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.7 2.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.7 3.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.7 11.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.7 8.8 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.7 2.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.7 13.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.6 3.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.6 1.9 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.6 4.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.5 2.7 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5 7.8 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 3.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.5 3.3 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.5 2.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.5 1.4 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.4 1.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 4.5 GO:0042908 xenobiotic transport(GO:0042908)
0.4 1.6 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.4 1.6 GO:0009189 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.4 1.2 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.4 4.6 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.4 3.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 0.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.4 8.9 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.4 3.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 1.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.7 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3 11.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.8 GO:0051012 microtubule sliding(GO:0051012)
0.3 2.1 GO:0051639 actin filament network formation(GO:0051639)
0.3 1.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 1.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 7.0 GO:0006825 copper ion transport(GO:0006825)
0.3 1.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 2.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 2.3 GO:0042262 DNA protection(GO:0042262)
0.2 0.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 2.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.6 GO:0032006 regulation of TOR signaling(GO:0032006)
0.2 1.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 1.0 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 1.6 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 0.9 GO:0048880 sensory system development(GO:0048880)
0.2 1.5 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.9 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.2 1.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.8 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.2 3.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 0.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 2.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 1.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 4.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.4 GO:1900158 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 5.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.2 GO:1902369 negative regulation of RNA catabolic process(GO:1902369) negative regulation of mRNA catabolic process(GO:1902373)
0.1 0.8 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.8 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.6 GO:0002467 germinal center formation(GO:0002467)
0.1 0.3 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 1.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 2.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.9 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1 1.2 GO:0007512 adult heart development(GO:0007512)
0.1 0.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 2.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1 1.0 GO:0007097 nuclear migration(GO:0007097)
0.1 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 3.4 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.2 GO:0070318 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.1 2.2 GO:0006833 water transport(GO:0006833)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.0 GO:0030903 notochord development(GO:0030903)
0.1 2.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 1.4 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 2.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 4.7 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.3 GO:0030916 otic vesicle formation(GO:0030916) otic vesicle morphogenesis(GO:0071600)
0.1 0.5 GO:0051451 myoblast migration(GO:0051451)
0.0 1.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 3.2 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 2.4 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.5 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 4.1 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 2.9 GO:0006415 translational termination(GO:0006415)
0.0 2.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 2.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 2.7 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 3.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0001842 neural fold formation(GO:0001842)
0.0 0.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.8 GO:0007498 mesoderm development(GO:0007498)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 2.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 10.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 2.7 GO:1990423 RZZ complex(GO:1990423)
0.6 5.2 GO:0005955 calcineurin complex(GO:0005955)
0.6 2.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 7.8 GO:0031045 dense core granule(GO:0031045)
0.5 3.6 GO:0045179 apical cortex(GO:0045179)
0.4 9.6 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.9 GO:0002177 manchette(GO:0002177)
0.3 2.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 6.8 GO:0030673 axolemma(GO:0030673)
0.2 10.4 GO:0031941 filamentous actin(GO:0031941)
0.2 0.8 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 1.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.9 GO:0000801 central element(GO:0000801)
0.2 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 2.0 GO:0005915 zonula adherens(GO:0005915)
0.2 7.5 GO:0031430 M band(GO:0031430)
0.2 12.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 9.6 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.3 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.0 GO:0016600 flotillin complex(GO:0016600)
0.1 1.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 6.3 GO:0005923 bicellular tight junction(GO:0005923)
0.1 7.9 GO:0030018 Z disc(GO:0030018)
0.1 6.7 GO:0043197 dendritic spine(GO:0043197)
0.1 11.4 GO:0043209 myelin sheath(GO:0043209)
0.1 40.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 5.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 19.7 GO:0045121 membrane raft(GO:0045121)
0.1 8.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 1.9 GO:0031904 endosome lumen(GO:0031904)
0.0 2.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 1.0 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.6 GO:0043679 axon terminus(GO:0043679)
0.0 3.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.0 GO:0031514 motile cilium(GO:0031514)
0.0 11.9 GO:0043005 neuron projection(GO:0043005)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0031975 organelle envelope(GO:0031967) envelope(GO:0031975)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.3 4.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.3 10.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 11.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 6.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 11.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.8 7.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 3.0 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6 3.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.6 1.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.6 4.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.6 1.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 5.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 3.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 2.3 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.5 2.3 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.4 2.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.4 2.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.3 0.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 1.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.3 2.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 2.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 2.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 8.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 2.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 7.5 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.2 2.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 4.7 GO:0031489 myosin V binding(GO:0031489)
0.2 1.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.8 GO:0015250 water channel activity(GO:0015250)
0.2 2.3 GO:0070330 aromatase activity(GO:0070330)
0.2 1.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 7.0 GO:0042056 chemoattractant activity(GO:0042056)
0.2 0.8 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 1.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 3.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 3.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 8.1 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 2.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:0033265 choline binding(GO:0033265)
0.1 4.8 GO:0030507 spectrin binding(GO:0030507)
0.1 2.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 5.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 4.5 GO:0050699 WW domain binding(GO:0050699)
0.1 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.9 GO:0031433 telethonin binding(GO:0031433)
0.1 1.0 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 9.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0050543 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 6.0 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 3.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 8.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 2.6 GO:0019843 rRNA binding(GO:0019843)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 2.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 2.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.6 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 4.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217) intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 3.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 14.5 GO:0008270 zinc ion binding(GO:0008270)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 3.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.6 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 4.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 15.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 4.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.1 PID AURORA A PATHWAY Aurora A signaling
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 4.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 5.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 7.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 11.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 7.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 4.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 3.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 8.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 4.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 2.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 3.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 6.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 5.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 8.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 4.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 4.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 9.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis