Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for HOXD1
Z-value: 0.82
Motif logo
Transcription factors associated with HOXD1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXD1 | hg19_v2_chr2_+_177053307_177053402 | -0.37 | 1.5e-08 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXD1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 14.2 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.5 | 9.6 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.3 | 7.0 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.5 | 6.3 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 1.9 | 5.8 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.1 | 5.8 | GO:0008542 | visual learning(GO:0008542) |
| 0.3 | 5.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 1.5 | 4.6 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.1 | 4.5 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.3 | 4.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 14.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 13.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 10.3 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.3 | 9.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.4 | 7.0 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.2 | 4.6 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.6 | 4.5 | GO:0005683 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.2 | 4.1 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 4.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 4.1 | GO:0005802 | trans-Golgi network(GO:0005802) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 14.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 13.1 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.2 | 7.0 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 5.8 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 5.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 1.5 | 4.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 1.5 | 4.5 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.3 | 4.1 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.2 | 4.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 4.1 | GO:0051015 | actin filament binding(GO:0051015) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.0 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 4.1 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 14.2 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 7.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 4.6 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.3 | 4.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.3 | 4.1 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 2.7 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.2 | 2.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 1.2 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 0.9 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |