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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for JDP2

Z-value: 0.19

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Transcription factors associated with JDP2

Gene Symbol Gene ID Gene Info
JDP2
ENSG00000140044.8 Jun dimerization protein 2

Activity profile of JDP2 motif

Sorted Z-values of JDP2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_175712270 22.94 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr20_-_62129163 17.70 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr12_+_7023735 15.35 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr12_+_7023491 14.88 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr7_+_97361218 14.18 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr3_-_98241760 13.95 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1
claudin domain containing 1
chr7_+_97361388 13.82 ENST00000350485.4
ENST00000346867.4
TAC1
tachykinin, precursor 1
chr16_+_15596123 13.55 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr13_-_36429763 10.87 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr8_-_27472198 10.83 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU
clusterin
chr20_+_4667094 10.67 ENST00000424424.1
ENST00000457586.1
PRNP
prion protein
chr12_+_10365404 10.51 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr20_+_4666882 10.04 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr3_-_98241358 9.72 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr13_-_67802549 7.15 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr16_+_57662138 7.11 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 6.31 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr12_+_57914742 6.26 ENST00000551351.1
MBD6
methyl-CpG binding domain protein 6
chr14_+_103800513 5.28 ENST00000560338.1
ENST00000560763.1
ENST00000558316.1
ENST00000558265.1
EIF5
eukaryotic translation initiation factor 5
chr9_-_35112376 5.25 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr12_+_124997766 5.16 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr2_-_145275228 5.01 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr16_+_89988259 4.61 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr3_+_183894566 4.51 ENST00000439647.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_-_56819385 4.49 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr7_+_48128316 4.44 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr1_-_67142710 4.36 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr7_+_48128194 4.28 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr3_+_155860751 4.26 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr2_-_220173685 4.24 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr18_+_21693306 4.14 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr12_+_75784850 4.07 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr12_-_71182695 4.05 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr3_-_122512619 3.93 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr9_-_91793675 3.89 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr3_+_69134080 3.87 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr7_+_30960915 3.67 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr12_+_107168342 3.60 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr3_-_18466026 3.51 ENST00000417717.2
SATB1
SATB homeobox 1
chr1_+_27719148 3.45 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr3_-_114343768 3.40 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_141774467 3.27 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr12_+_107168418 3.24 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr3_+_69134124 3.22 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr17_+_76311791 3.17 ENST00000586321.1
AC061992.2
AC061992.2
chr1_+_213224572 3.17 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
RPS6KC1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr17_-_8263538 3.09 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr1_-_244006528 3.07 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_-_80551671 2.99 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_38386175 2.98 ENST00000437935.2
ENST00000358138.1
C8orf86
chromosome 8 open reading frame 86
chr10_+_1102721 2.97 ENST00000263150.4
WDR37
WD repeat domain 37
chr9_-_23826298 2.96 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr17_+_66539369 2.93 ENST00000600820.1
AC079210.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chr9_+_34958254 2.93 ENST00000242315.3
KIAA1045
KIAA1045
chr12_-_719573 2.92 ENST00000397265.3
NINJ2
ninjurin 2
chr5_-_149492904 2.88 ENST00000286301.3
ENST00000511344.1
CSF1R
colony stimulating factor 1 receptor
chr7_+_147830776 2.87 ENST00000538075.1
CNTNAP2
contactin associated protein-like 2
chr13_+_32838801 2.81 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr12_-_57914275 2.80 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr7_-_135433460 2.69 ENST00000415751.1
FAM180A
family with sequence similarity 180, member A
chr20_-_48782639 2.68 ENST00000435301.2
RP11-112L6.3
RP11-112L6.3
chr4_-_36246060 2.66 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_18466787 2.64 ENST00000338745.6
ENST00000450898.1
SATB1
SATB homeobox 1
chr12_+_6644443 2.63 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr11_-_2924720 2.60 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr7_-_14942283 2.60 ENST00000402815.1
DGKB
diacylglycerol kinase, beta 90kDa
chr10_+_88428206 2.53 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr10_-_120514720 2.48 ENST00000369151.3
ENST00000340214.4
CACUL1
CDK2-associated, cullin domain 1
chr3_-_149293990 2.46 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr12_-_48152611 2.42 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr12_-_48152853 2.41 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_30771279 2.31 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_+_183903811 2.29 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr9_-_124991124 2.23 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr12_-_56101647 2.21 ENST00000347027.6
ENST00000257879.6
ENST00000257880.7
ENST00000394230.2
ENST00000394229.2
ITGA7
integrin, alpha 7
chr16_+_28996416 2.19 ENST00000395456.2
ENST00000454369.2
LAT
linker for activation of T cells
chr11_-_82708519 2.18 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr19_+_50706866 2.15 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr20_-_17539456 2.12 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr8_-_110988070 2.09 ENST00000524391.1
KCNV1
potassium channel, subfamily V, member 1
chr4_+_170581213 2.08 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr9_-_21335240 2.07 ENST00000537938.1
KLHL9
kelch-like family member 9
chrY_+_15016725 2.04 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_+_154377669 2.01 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr17_+_79650962 1.98 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr9_-_21335356 1.96 ENST00000359039.4
KLHL9
kelch-like family member 9
chr19_-_4455290 1.90 ENST00000394765.3
ENST00000592515.1
UBXN6
UBX domain protein 6
chrX_-_48901012 1.89 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr9_+_140135665 1.86 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr17_-_73775839 1.84 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr11_-_75201791 1.79 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr6_+_10521574 1.77 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_+_151042224 1.74 ENST00000358517.2
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_161695042 1.69 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr11_-_2924970 1.68 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr12_-_8218997 1.68 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr4_+_71588372 1.65 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr7_+_28725585 1.56 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr16_+_30077098 1.56 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr4_+_120056939 1.54 ENST00000307128.5
MYOZ2
myozenin 2
chr19_-_5903714 1.54 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr15_+_89182156 1.52 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr16_+_30077055 1.52 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr1_-_153521597 1.50 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr11_-_84028180 1.48 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chrX_-_15288154 1.48 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr11_-_66103932 1.48 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr10_+_88428370 1.46 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr6_-_161695074 1.45 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr8_-_42623924 1.43 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_-_153521714 1.32 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr17_+_25799008 1.30 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr16_+_28996114 1.29 ENST00000395461.3
LAT
linker for activation of T cells
chr17_+_66245341 1.28 ENST00000577985.1
AMZ2
archaelysin family metallopeptidase 2
chr21_-_36421626 1.28 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr21_-_36421535 1.28 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr12_-_7818474 1.28 ENST00000229304.4
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr1_+_17634689 1.23 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr1_-_51796987 1.20 ENST00000262676.5
TTC39A
tetratricopeptide repeat domain 39A
chr6_-_49755019 1.18 ENST00000304801.3
PGK2
phosphoglycerate kinase 2
chr7_+_134528635 1.14 ENST00000445569.2
CALD1
caldesmon 1
chr5_-_75919253 1.10 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr17_-_33760269 1.07 ENST00000452764.3
SLFN12
schlafen family member 12
chr4_+_3388057 1.02 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr1_-_160231451 1.01 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr6_+_106534192 1.00 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr16_+_9449445 1.00 ENST00000564305.1
RP11-243A14.1
RP11-243A14.1
chr9_-_21207142 0.96 ENST00000357374.2
IFNA10
interferon, alpha 10
chr22_+_39916558 0.92 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr8_+_15397732 0.91 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chrX_+_1733876 0.80 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr4_+_175839551 0.79 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr5_+_35856951 0.76 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr1_-_204121013 0.76 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr11_+_5009424 0.76 ENST00000300762.1
MMP26
matrix metallopeptidase 26
chr16_+_31366536 0.71 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_102826434 0.70 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr2_+_233562015 0.69 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr22_+_20861858 0.69 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr8_-_42623747 0.68 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_-_204121102 0.66 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr11_-_66103867 0.65 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr17_+_55162453 0.64 ENST00000575322.1
ENST00000337714.3
ENST00000314126.3
AKAP1
A kinase (PRKA) anchor protein 1
chr4_+_175839506 0.63 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr2_+_152214098 0.62 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr18_+_2846972 0.61 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr3_+_48507210 0.60 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr17_+_74381343 0.60 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr4_-_122085469 0.60 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr11_-_66104237 0.58 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr11_-_102668879 0.53 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr21_-_36421401 0.52 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr10_+_52152766 0.51 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr1_-_111148241 0.50 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr20_+_30946106 0.50 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr7_+_127233689 0.49 ENST00000265825.5
ENST00000420086.2
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chrX_+_57618269 0.47 ENST00000374888.1
ZXDB
zinc finger, X-linked, duplicated B
chr9_-_34662651 0.47 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr12_+_52695617 0.47 ENST00000293525.5
KRT86
keratin 86
chr4_-_100356551 0.44 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr16_+_2083265 0.42 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr1_-_204121298 0.41 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr5_+_177540444 0.39 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr16_+_28996364 0.39 ENST00000564277.1
LAT
linker for activation of T cells
chr2_+_69201705 0.38 ENST00000377938.2
GKN1
gastrokine 1
chr2_+_166326157 0.36 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr1_-_13117736 0.33 ENST00000376192.5
ENST00000376182.1
PRAMEF6
PRAME family member 6
chr6_-_31745037 0.30 ENST00000375688.4
VWA7
von Willebrand factor A domain containing 7
chr6_+_72596406 0.29 ENST00000491071.2
RIMS1
regulating synaptic membrane exocytosis 1
chr1_+_13359819 0.29 ENST00000376168.1
PRAMEF5
PRAME family member 5
chr10_-_21463116 0.28 ENST00000417816.2
NEBL
nebulette
chr4_-_100356291 0.26 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_151227179 0.26 ENST00000368884.3
ENST00000368881.4
PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr6_+_122720681 0.25 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr11_+_67250490 0.25 ENST00000528641.2
ENST00000279146.3
AIP
aryl hydrocarbon receptor interacting protein
chr11_-_102714534 0.25 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr18_+_61442629 0.23 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_194090460 0.23 ENST00000428839.1
ENST00000347624.3
LRRC15
leucine rich repeat containing 15
chr4_-_987217 0.19 ENST00000361661.2
ENST00000398516.2
SLC26A1
solute carrier family 26 (anion exchanger), member 1
chr2_+_202122703 0.19 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr4_-_100356844 0.18 ENST00000437033.2
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_+_19988885 0.17 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr16_+_31366455 0.15 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr7_-_155604967 0.15 ENST00000297261.2
SHH
sonic hedgehog
chr5_-_75919217 0.14 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr1_-_13007420 0.14 ENST00000376189.1
PRAMEF6
PRAME family member 6
chr3_+_48507621 0.09 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chrX_+_1734051 0.05 ENST00000381229.4
ENST00000381233.3
ASMT
acetylserotonin O-methyltransferase
chr11_+_82783097 0.02 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr9_+_138453595 0.02 ENST00000479141.1
ENST00000371766.2
ENST00000277508.5
ENST00000433563.1
PAEP
progestagen-associated endometrial protein
chr20_+_43029911 0.01 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr5_+_179247759 0.00 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
6.9 20.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
2.7 13.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
2.2 8.7 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.8 10.8 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.4 4.2 GO:1990502 dense core granule maturation(GO:1990502)
1.3 5.0 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.2 3.7 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
1.2 4.8 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
1.0 3.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.0 2.9 GO:0071109 superior temporal gyrus development(GO:0071109)
0.9 17.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 7.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.9 2.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.7 2.8 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.7 33.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.7 4.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.7 2.0 GO:0002384 hepatic immune response(GO:0002384)
0.7 22.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.6 10.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5 2.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 4.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.5 10.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.4 2.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 3.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.4 6.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 2.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.4 2.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 2.9 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145) cell-cell junction maintenance(GO:0045217)
0.3 0.9 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3 0.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.3 0.9 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.3 4.3 GO:1902260 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.3 1.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 1.9 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 2.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 1.3 GO:0016554 cytidine to uridine editing(GO:0016554) DNA cytosine deamination(GO:0070383)
0.2 3.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 1.0 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 3.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 3.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.8 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 2.6 GO:0043248 proteasome assembly(GO:0043248)
0.2 4.7 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 2.1 GO:0071625 vocalization behavior(GO:0071625)
0.1 2.0 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.1 1.5 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.5 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 3.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.9 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.1 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 2.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.2 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 3.9 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 1.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.3 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 1.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 7.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 7.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.2 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0051036 regulation of endosome size(GO:0051036)
0.0 8.5 GO:0007411 axon guidance(GO:0007411)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 1.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.7 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 4.0 GO:0000910 cytokinesis(GO:0000910)
0.0 0.6 GO:0030728 ovulation(GO:0030728)
0.0 1.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 5.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 30.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.8 17.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.3 20.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.2 3.7 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.1 4.5 GO:0031673 H zone(GO:0031673)
0.9 2.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.7 5.0 GO:1990635 proximal dendrite(GO:1990635)
0.7 10.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.7 2.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.5 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 3.0 GO:0070545 PeBoW complex(GO:0070545)
0.5 2.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.4 2.1 GO:0097513 myosin II filament(GO:0097513)
0.4 10.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 2.6 GO:0097452 GAIT complex(GO:0097452)
0.3 6.3 GO:0010369 chromocenter(GO:0010369)
0.3 3.4 GO:0033010 paranodal junction(GO:0033010)
0.2 4.5 GO:0036020 endolysosome membrane(GO:0036020)
0.2 2.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 6.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 4.0 GO:0031143 pseudopodium(GO:0031143)
0.2 0.9 GO:1990037 Lewy body core(GO:1990037)
0.1 1.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.9 GO:0042629 mast cell granule(GO:0042629)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.6 GO:0071437 invadopodium(GO:0071437)
0.1 5.3 GO:0005902 microvillus(GO:0005902)
0.1 3.1 GO:0031430 M band(GO:0031430)
0.1 6.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 4.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 27.2 GO:0030424 axon(GO:0030424)
0.0 10.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 8.3 GO:0030425 dendrite(GO:0030425)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 3.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 17.2 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 30.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.5 20.7 GO:1903135 cupric ion binding(GO:1903135)
2.2 8.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.2 3.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.8 10.5 GO:0030957 Tat protein binding(GO:0030957)
0.7 28.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.7 2.0 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.7 2.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7 17.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 1.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5 10.8 GO:0051787 misfolded protein binding(GO:0051787)
0.5 22.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.4 1.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 1.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.4 4.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 2.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.5 GO:0051373 FATZ binding(GO:0051373)
0.3 1.5 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.3 3.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 0.8 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.3 1.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.9 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.2 6.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 3.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 4.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 3.3 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 4.3 GO:0070402 NADPH binding(GO:0070402)
0.2 3.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 4.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 4.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 4.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.7 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 5.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 4.2 GO:0030507 spectrin binding(GO:0030507)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 3.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 5.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 10.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.9 GO:0019955 cytokine binding(GO:0019955)
0.0 2.8 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 20.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 22.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 6.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 4.5 PID ARF 3PATHWAY Arf1 pathway
0.2 4.5 ST GA12 PATHWAY G alpha 12 Pathway
0.2 3.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.0 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 13.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 5.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.7 PID AURORA B PATHWAY Aurora B signaling
0.0 2.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 3.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 2.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 35.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.6 8.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 20.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 3.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 3.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 4.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 6.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 3.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 8.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 29.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 6.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 18.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 10.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle