Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for JDP2
Z-value: 0.19
Motif logo
Transcription factors associated with JDP2
Network of associatons between targets according to the STRING database.
First level regulatory network of JDP2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 33.3 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 9.3 | 28.0 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 0.7 | 22.9 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 6.9 | 20.7 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
| 0.9 | 17.7 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 2.7 | 13.5 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 0.5 | 10.9 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 1.8 | 10.8 | GO:0061518 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.6 | 10.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 2.2 | 8.7 | GO:0046108 | uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 30.2 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 27.2 | GO:0030424 | axon(GO:0030424) |
| 1.3 | 20.7 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 1.8 | 17.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 17.2 | GO:0015630 | microtubule cytoskeleton(GO:0015630) |
| 0.0 | 10.9 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.7 | 10.8 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.4 | 10.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 8.3 | GO:0030425 | dendrite(GO:0030425) |
| 0.1 | 6.6 | GO:0044291 | cell-cell contact zone(GO:0044291) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 30.2 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.7 | 28.0 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.5 | 22.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 3.5 | 20.7 | GO:1903135 | cupric ion binding(GO:1903135) |
| 0.7 | 17.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.5 | 10.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.8 | 10.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 10.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 2.2 | 8.7 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.2 | 6.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 22.9 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.4 | 20.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 13.6 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.2 | 6.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 5.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 4.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.2 | 4.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.2 | 3.9 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 3.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 3.1 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 35.9 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 29.5 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.3 | 20.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 18.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 10.8 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.6 | 8.7 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.2 | 8.1 | REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.1 | 6.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 6.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.3 | 4.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |