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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for JUN

Z-value: 0.40

Motif logo

Transcription factors associated with JUN

Gene Symbol Gene ID Gene Info
ENSG00000177606.5 Jun proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
JUNhg19_v2_chr1_-_59249732_592497850.054.9e-01Click!

Activity profile of JUN motif

Sorted Z-values of JUN motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_27115931 29.07 ENST00000523048.1
stathmin-like 4
chr8_-_27115903 24.71 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
stathmin-like 4
chr5_-_139944196 24.28 ENST00000357560.4
amyloid beta (A4) precursor protein-binding, family B, member 3
chr22_-_44258360 24.11 ENST00000330884.4
ENST00000249130.5
sulfotransferase family 4A, member 1
chr6_+_121756809 18.90 ENST00000282561.3
gap junction protein, alpha 1, 43kDa
chr5_+_71403061 18.59 ENST00000512974.1
ENST00000296755.7
microtubule-associated protein 1B
chr11_-_1593150 17.47 ENST00000397374.3
dual specificity phosphatase 8
chr5_-_139943830 16.48 ENST00000412920.3
ENST00000511201.2
ENST00000356738.2
ENST00000354402.5
ENST00000358580.5
ENST00000508496.2
amyloid beta (A4) precursor protein-binding, family B, member 3
chr1_+_36023370 16.08 ENST00000356090.4
ENST00000373243.2
neurochondrin
chrX_-_13835461 15.96 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr1_+_28099683 15.89 ENST00000373943.4
syntaxin 12
chr20_-_3154162 15.84 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr12_+_10365404 14.97 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr11_+_117070037 14.89 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr1_+_151030234 14.80 ENST00000368921.3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_+_149632783 14.41 ENST00000435030.1
kinesin family member 5C
chr6_-_46293378 14.25 ENST00000330430.6
regulator of calcineurin 2
chr18_-_5540471 13.67 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
erythrocyte membrane protein band 4.1-like 3
chr16_+_2039946 13.17 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr14_+_93389425 12.65 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr11_+_17281900 12.44 ENST00000530527.1
nucleobindin 2
chrX_-_47479246 11.93 ENST00000295987.7
ENST00000340666.4
synapsin I
chr3_+_158991025 11.76 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chrX_-_92928557 11.40 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr1_-_230850043 11.38 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr2_-_216300784 11.09 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr3_+_10068095 10.87 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr2_-_224467093 10.59 ENST00000305409.2
secretogranin II
chr15_+_68871569 10.48 ENST00000566799.1
coronin, actin binding protein, 2B
chr6_-_3157760 10.44 ENST00000333628.3
tubulin, beta 2A class IIa
chr15_+_68871308 10.31 ENST00000261861.5
coronin, actin binding protein, 2B
chr16_+_29911666 10.22 ENST00000563177.1
ENST00000483405.1
aspartate beta-hydroxylase domain containing 1
chr6_-_56819385 9.56 ENST00000370754.5
ENST00000449297.2
dystonin
chr16_+_29911864 9.55 ENST00000308748.5
aspartate beta-hydroxylase domain containing 1
chr3_+_62304712 9.41 ENST00000494481.1
chromosome 3 open reading frame 14
chr10_-_27444143 9.27 ENST00000477432.1
YME1-like 1 ATPase
chr15_+_45879321 9.07 ENST00000220531.3
ENST00000567461.1
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr3_+_159570722 9.00 ENST00000482804.1
schwannomin interacting protein 1
chr10_+_64133934 8.94 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chrX_+_110339439 8.92 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
p21 protein (Cdc42/Rac)-activated kinase 3
chr16_+_56225248 8.91 ENST00000262493.6
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_100485712 8.86 ENST00000544450.2
Enah/Vasp-like
chr1_+_228353495 8.66 ENST00000366711.3
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr5_-_138210977 8.62 ENST00000274711.6
ENST00000521094.2
leucine rich repeat transmembrane neuronal 2
chr11_-_123525289 8.54 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr12_-_16761007 8.47 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr3_+_62304648 8.40 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chr1_+_163039143 8.31 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr6_+_111580508 8.21 ENST00000368847.4
KIAA1919
chr19_+_57831829 8.18 ENST00000321545.4
zinc finger protein 543
chr19_+_42772659 8.03 ENST00000572681.2
capicua transcriptional repressor
chr20_+_5892037 7.98 ENST00000378961.4
chromogranin B (secretogranin 1)
chr5_+_140864649 7.90 ENST00000306593.1
protocadherin gamma subfamily C, 4
chr3_+_50712672 7.81 ENST00000266037.9
dedicator of cytokinesis 3
chr5_-_176056974 7.66 ENST00000510387.1
ENST00000506696.1
synuclein, beta
chr6_+_31783291 7.57 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr19_-_48614033 7.54 ENST00000354276.3
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr16_-_90038866 7.53 ENST00000314994.3
CENPB DNA-binding domains containing 1
chr17_+_42385927 7.50 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A
chr17_+_40610862 7.50 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr19_-_48614063 7.49 ENST00000599921.1
ENST00000599111.1
phospholipase A2, group IVC (cytosolic, calcium-independent)
chr13_+_53226963 7.25 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr1_+_168148273 7.15 ENST00000367830.3
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr19_+_2841433 7.11 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
zinc finger protein 555
chr11_-_31839488 7.06 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
paired box 6
chr9_-_113761720 7.02 ENST00000541779.1
ENST00000374430.2
lysophosphatidic acid receptor 1
chr22_+_51176624 7.00 ENST00000216139.5
ENST00000529621.1
acrosin
chr21_-_44299626 6.99 ENST00000330317.2
ENST00000398208.2
WD repeat domain 4
chr7_-_45128472 6.92 ENST00000490531.2
NAC alpha domain containing
chr15_+_75287861 6.87 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
secretory carrier membrane protein 5
chr14_+_104095514 6.86 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
kinesin light chain 1
chr16_+_22825475 6.75 ENST00000261374.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_18314836 6.73 ENST00000464076.3
ENST00000222256.4
RAB3A, member RAS oncogene family
chr1_-_201476274 6.69 ENST00000340006.2
cysteine and glycine-rich protein 1
chr12_+_124997766 6.66 ENST00000543970.1
RP11-83B20.1
chr20_+_17207665 6.64 ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr22_+_32340481 6.62 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr14_-_36278454 6.60 ENST00000307138.6
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr15_+_42841008 6.59 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr15_+_93749295 6.56 ENST00000599897.1
AC112693.2
chr17_-_71308119 6.53 ENST00000439510.2
ENST00000581014.1
ENST00000579611.1
CDC42 effector protein (Rho GTPase binding) 4
chr15_-_30113676 6.46 ENST00000400011.2
tight junction protein 1
chr2_-_216257849 6.46 ENST00000456923.1
fibronectin 1
chr11_+_1463728 6.42 ENST00000544817.1
BR serine/threonine kinase 2
chr2_-_238322770 6.34 ENST00000472056.1
collagen, type VI, alpha 3
chr14_-_103523745 6.29 ENST00000361246.2
CDC42 binding protein kinase beta (DMPK-like)
chr20_+_17207636 6.25 ENST00000262545.2
proprotein convertase subtilisin/kexin type 2
chr2_-_238323007 6.22 ENST00000295550.4
collagen, type VI, alpha 3
chr19_+_18723660 6.19 ENST00000262817.3
transmembrane protein 59-like
chr16_+_2564254 6.09 ENST00000565223.1
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr14_-_36278412 6.06 ENST00000389698.3
ENST00000258840.6
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr19_+_8455200 6.05 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chrX_+_16737718 6.04 ENST00000380155.3
synapse associated protein 1
chr7_+_35840819 6.02 ENST00000399035.3
septin 7
chr5_-_133706695 6.01 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr19_-_56826157 6.00 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr7_+_35840542 5.96 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
septin 7
chr14_+_35515598 5.89 ENST00000280987.4
family with sequence similarity 177, member A1
chr2_-_238322800 5.86 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
collagen, type VI, alpha 3
chr22_+_32340447 5.78 ENST00000248975.5
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr9_-_99381660 5.71 ENST00000375240.3
ENST00000463569.1
cell division cycle 14B
chr10_+_134351319 5.68 ENST00000368594.3
ENST00000368593.3
inositol polyphosphate-5-phosphatase, 40kDa
chr20_+_34203794 5.64 ENST00000374273.3
sperm associated antigen 4
chr1_-_1293904 5.62 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
matrix-remodelling associated 8
chr18_+_23806437 5.56 ENST00000578121.1
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr9_-_99382065 5.52 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
cell division cycle 14B
chr14_-_93651186 5.50 ENST00000556883.1
ENST00000298894.4
modulator of apoptosis 1
chr11_+_28129795 5.47 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr3_-_187388173 5.38 ENST00000287641.3
somatostatin
chr2_-_241759622 5.36 ENST00000320389.7
ENST00000498729.2
kinesin family member 1A
chr19_-_40919271 5.30 ENST00000291825.7
ENST00000324001.7
periaxin
chr12_+_7282795 5.30 ENST00000266546.6
calsyntenin 3
chr1_-_76076759 5.26 ENST00000370855.5
solute carrier family 44, member 5
chr1_+_27719148 5.26 ENST00000374024.3
G protein-coupled receptor 3
chr3_-_52001448 5.18 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr3_-_48130707 5.17 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chr1_-_713985 5.11 ENST00000428504.1
RP11-206L10.2
chr19_+_57791419 5.02 ENST00000537645.1
zinc finger protein 460
chr3_-_33759541 4.98 ENST00000468888.2
cytoplasmic linker associated protein 2
chr7_-_44924939 4.98 ENST00000395699.2
purine-rich element binding protein B
chr9_-_131644202 4.96 ENST00000320665.6
ENST00000436267.2
cysteine conjugate-beta lyase, cytoplasmic
chr3_-_48130314 4.96 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
microtubule-associated protein 4
chr6_-_116575226 4.95 ENST00000420283.1
TSPY-like 4
chr8_-_21966893 4.93 ENST00000522405.1
ENST00000522379.1
ENST00000309188.6
ENST00000521807.2
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr5_-_95297534 4.91 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr11_-_116968987 4.91 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr19_-_10341948 4.87 ENST00000590320.1
ENST00000592342.1
ENST00000588952.1
sphingosine-1-phosphate receptor 2
DNA (cytosine-5-)-methyltransferase 1
chr7_-_31380502 4.87 ENST00000297142.3
neuronal differentiation 6
chr14_-_75389975 4.86 ENST00000555647.1
ENST00000557413.1
ribosomal protein S6 kinase-like 1
chr14_+_96722152 4.82 ENST00000216629.6
bradykinin receptor B1
chr9_+_111624577 4.79 ENST00000333999.3
actin-like 7A
chr6_-_31940065 4.77 ENST00000375349.3
ENST00000337523.5
decapping exoribonuclease
chr1_+_25071848 4.75 ENST00000374379.4
chloride intracellular channel 4
chr18_+_76829441 4.72 ENST00000458297.2
ATPase, class II, type 9B
chr7_+_30960915 4.71 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr19_-_49622348 4.67 ENST00000408991.2
chromosome 19 open reading frame 73
chr16_+_27561449 4.67 ENST00000261588.4
KIAA0556
chr11_+_108535849 4.67 ENST00000526794.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr19_+_7011509 4.59 ENST00000377296.3
Uncharacterized protein
chr7_+_4721885 4.57 ENST00000328914.4
forkhead box K1
chr10_-_61720640 4.56 ENST00000521074.1
ENST00000444900.1
chromosome 10 open reading frame 40
chr8_+_125954281 4.54 ENST00000510897.2
ENST00000533286.1
long intergenic non-protein coding RNA 964
chr8_+_79428539 4.52 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr5_-_131892501 4.48 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr3_-_9994021 4.48 ENST00000411976.2
ENST00000412055.1
proline-rich transmembrane protein 3
chr19_-_5340730 4.48 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr6_+_151042224 4.48 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr6_-_121655552 4.38 ENST00000275159.6
TBC1 domain family, member 32
chr12_+_58138800 4.34 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
tetraspanin 31
chr16_+_89989687 4.27 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr13_+_111855414 4.26 ENST00000375737.5
Rho guanine nucleotide exchange factor (GEF) 7
chr6_+_27833034 4.25 ENST00000357320.2
histone cluster 1, H2al
chr2_-_220174166 4.25 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
protein tyrosine phosphatase, receptor type, N
chr2_-_220173685 4.23 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
protein tyrosine phosphatase, receptor type, N
chr4_+_85504075 4.21 ENST00000295887.5
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr19_+_8455077 4.19 ENST00000328024.6
RAB11B, member RAS oncogene family
chr22_+_17082732 4.17 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr2_+_70142189 4.09 ENST00000264444.2
MAX dimerization protein 1
chr2_+_241375069 4.09 ENST00000264039.2
glypican 1
chr11_-_14993819 4.08 ENST00000396372.2
ENST00000361010.3
ENST00000359642.3
ENST00000331587.4
calcitonin-related polypeptide alpha
chr1_-_120439112 4.06 ENST00000369400.1
ADAM metallopeptidase domain 30
chr13_+_49822041 4.05 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
cytidine and dCMP deaminase domain containing 1
chr2_+_70142232 4.04 ENST00000540449.1
MAX dimerization protein 1
chr6_+_44355257 4.04 ENST00000371477.3
cell division cycle 5-like
chr7_+_100551239 4.03 ENST00000319509.7
mucin 3A, cell surface associated
chr19_+_49622646 4.03 ENST00000334186.4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_-_63381925 3.99 ENST00000415826.1
phospholipase A2, group XVI
chr3_+_148447887 3.97 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr3_-_33759699 3.95 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
cytoplasmic linker associated protein 2
chr11_+_117014983 3.94 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr7_-_37956409 3.93 ENST00000436072.2
secreted frizzled-related protein 4
chr11_-_85376121 3.93 ENST00000527447.1
CREB/ATF bZIP transcription factor
chr9_-_140115775 3.92 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr15_-_80634104 3.91 ENST00000561432.1
ENST00000558913.1
ENST00000558578.1
long intergenic non-protein coding RNA 927
chr6_-_34664612 3.87 ENST00000374023.3
ENST00000374026.3
chromosome 6 open reading frame 106
chr21_+_34398153 3.86 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
oligodendrocyte lineage transcription factor 2
chr7_+_5632436 3.85 ENST00000340250.6
ENST00000382361.3
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr13_-_52378231 3.81 ENST00000280056.2
ENST00000444610.2
dehydrogenase/reductase (SDR family) member 12
chr4_+_114214125 3.79 ENST00000509550.1
ankyrin 2, neuronal
chr1_-_203274418 3.76 ENST00000457348.1
long intergenic non-protein coding RNA 1136
chr3_-_99594948 3.76 ENST00000471562.1
ENST00000495625.2
filamin A interacting protein 1-like
chr10_-_29811456 3.73 ENST00000535393.1
supervillin
chr11_+_61520075 3.73 ENST00000278836.5
myelin regulatory factor
chr3_-_114343768 3.71 ENST00000393785.2
zinc finger and BTB domain containing 20
chr6_-_41888814 3.70 ENST00000409060.1
ENST00000265350.4
mediator complex subunit 20
chr12_-_48164812 3.70 ENST00000549151.1
ENST00000548919.1
Rap guanine nucleotide exchange factor (GEF) 3
chr14_+_65381079 3.66 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr6_-_31782813 3.63 ENST00000375654.4
heat shock 70kDa protein 1-like
chr3_-_15469006 3.61 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
methyltransferase like 6
chr20_-_44600810 3.57 ENST00000322927.2
ENST00000426788.1
zinc finger protein 335
chr12_-_6772303 3.57 ENST00000396807.4
ENST00000446105.2
ENST00000341550.4
inhibitor of growth family, member 4
chr1_-_26233423 3.52 ENST00000357865.2
stathmin 1
chr14_-_75389925 3.51 ENST00000556776.1
ribosomal protein S6 kinase-like 1
chr8_+_38243821 3.48 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr9_-_131644306 3.44 ENST00000302586.3
cysteine conjugate-beta lyase, cytoplasmic
chr19_+_17830051 3.43 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
microtubule-associated protein 1S
chrX_-_7895755 3.42 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr7_-_142176790 3.42 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr8_-_42065187 3.41 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
plasminogen activator, tissue
chr12_+_52668394 3.40 ENST00000423955.2
keratin 86

Network of associatons between targets according to the STRING database.

First level regulatory network of JUN

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
4.7 18.9 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
4.2 12.6 GO:0061110 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
3.8 11.4 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
2.8 8.5 GO:1990502 dense core granule maturation(GO:1990502)
2.6 12.9 GO:0030070 insulin processing(GO:0030070)
2.4 12.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
2.2 6.7 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.2 6.5 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
2.1 6.4 GO:1990637 response to prolactin(GO:1990637)
2.1 8.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.0 13.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
1.9 7.6 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
1.8 10.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.8 7.0 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.7 3.4 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
1.6 9.8 GO:0051012 microtubule sliding(GO:0051012)
1.6 16.0 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 4.7 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
1.5 9.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.5 6.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
1.5 6.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
1.5 9.1 GO:0030035 microspike assembly(GO:0030035)
1.5 4.5 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.5 4.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
1.4 4.3 GO:0046066 dGDP metabolic process(GO:0046066)
1.4 7.1 GO:0003322 pancreatic A cell development(GO:0003322)
1.4 8.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.4 4.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
1.4 6.9 GO:0035617 stress granule disassembly(GO:0035617)
1.4 4.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.4 66.4 GO:0007019 microtubule depolymerization(GO:0007019)
1.3 4.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
1.3 3.9 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
1.3 3.9 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 3.8 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 4.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.2 7.2 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.1 10.2 GO:0045054 constitutive secretory pathway(GO:0045054)
1.1 18.6 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
1.1 3.3 GO:0090427 activation of meiosis(GO:0090427)
1.1 3.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.1 9.6 GO:0008090 retrograde axonal transport(GO:0008090)
1.0 4.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
1.0 8.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 3.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.0 19.0 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
1.0 7.0 GO:0007341 penetration of zona pellucida(GO:0007341)
1.0 2.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.0 8.8 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.0 2.9 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
1.0 2.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.9 10.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.9 3.7 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.9 8.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.9 6.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.9 3.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.9 15.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.9 3.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.9 2.6 GO:0061386 closure of optic fissure(GO:0061386)
0.8 2.5 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.8 4.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.8 2.3 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.8 5.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.7 11.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.7 14.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.7 8.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.7 12.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.7 8.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.7 1.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.7 1.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.7 6.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.7 2.1 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.7 5.5 GO:0070475 rRNA base methylation(GO:0070475)
0.7 2.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.7 24.1 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.7 6.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.6 9.1 GO:0016081 synaptic vesicle docking(GO:0016081) positive regulation of pigment cell differentiation(GO:0050942)
0.6 1.9 GO:1990108 protein linear deubiquitination(GO:1990108)
0.6 25.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.6 3.7 GO:0018343 protein farnesylation(GO:0018343)
0.6 2.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.6 4.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.6 12.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.6 12.2 GO:0007035 vacuolar acidification(GO:0007035)
0.5 2.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.5 6.1 GO:0015871 choline transport(GO:0015871)
0.5 1.0 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.5 4.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 3.9 GO:0070166 enamel mineralization(GO:0070166)
0.5 5.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 5.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.5 1.4 GO:0043605 cellular amide catabolic process(GO:0043605)
0.4 1.3 GO:0048382 mesendoderm development(GO:0048382)
0.4 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 2.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.4 6.4 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.4 6.8 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.4 14.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.4 3.0 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 3.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.4 1.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.4 6.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.4 16.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.4 2.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 8.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 3.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 8.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 3.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 2.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.4 5.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.4 5.2 GO:0000338 protein deneddylation(GO:0000338)
0.4 2.6 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.4 1.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 1.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.4 1.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 1.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.4 1.8 GO:2000323 regulation of glucocorticoid receptor signaling pathway(GO:2000322) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.4 1.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 1.4 GO:2000259 positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.3 3.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.3 13.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 5.6 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.3 6.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 4.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 7.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.3 16.8 GO:0033344 cholesterol efflux(GO:0033344)
0.3 1.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.3 1.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 4.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 1.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.3 1.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.3 4.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 1.6 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.2 2.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 4.2 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.2 1.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 18.3 GO:0030574 collagen catabolic process(GO:0030574)
0.2 7.8 GO:0042730 fibrinolysis(GO:0042730)
0.2 3.6 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 7.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 2.5 GO:0000050 urea cycle(GO:0000050)
0.2 6.0 GO:0030517 negative regulation of axon extension(GO:0030517)
0.2 1.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 0.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.2 0.2 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.2 1.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 1.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 1.3 GO:0061042 vascular wound healing(GO:0061042)
0.2 6.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 0.7 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 3.7 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 5.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 0.9 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.7 GO:0003335 corneocyte development(GO:0003335)
0.2 0.2 GO:0002874 chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 10.4 GO:0021762 substantia nigra development(GO:0021762)
0.2 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 6.9 GO:0042417 dopamine metabolic process(GO:0042417)
0.2 5.2 GO:0007286 spermatid development(GO:0007286)
0.1 5.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 1.6 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 0.5 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 1.8 GO:0001660 fever generation(GO:0001660)
0.1 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 5.9 GO:0010107 potassium ion import(GO:0010107)
0.1 3.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.1 GO:0034389 lipid particle organization(GO:0034389)
0.1 11.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 3.4 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 1.4 GO:0001842 neural fold formation(GO:0001842)
0.1 2.9 GO:0021542 dentate gyrus development(GO:0021542)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 2.2 GO:0003094 glomerular filtration(GO:0003094)
0.1 5.0 GO:0035329 hippo signaling(GO:0035329)
0.1 1.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.9 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 2.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 1.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 12.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.2 GO:1904776 protein localization to cell cortex(GO:0072697) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 3.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.4 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 3.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 4.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 4.8 GO:0070268 cornification(GO:0070268)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 3.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.8 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 3.1 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.1 5.7 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.1 4.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 3.9 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.3 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418) negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone biosynthetic process(GO:1901663)
0.1 1.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 3.9 GO:0048477 oogenesis(GO:0048477)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 5.4 GO:0045995 regulation of embryonic development(GO:0045995)
0.1 1.0 GO:0035456 response to interferon-beta(GO:0035456)
0.1 3.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.8 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.8 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 1.0 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 15.1 GO:0007517 muscle organ development(GO:0007517)
0.0 1.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 3.5 GO:0007272 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 1.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 5.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 3.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.2 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.5 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0007507 heart development(GO:0007507)
0.0 0.0 GO:0097154 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) GABAergic neuron differentiation(GO:0097154)
0.0 0.2 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 3.0 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0043159 acrosomal matrix(GO:0043159)
2.4 9.6 GO:0031673 H zone(GO:0031673)
2.0 4.0 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
1.8 16.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.6 4.7 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.4 25.0 GO:0031083 BLOC-1 complex(GO:0031083)
1.4 17.6 GO:0005577 fibrinogen complex(GO:0005577)
1.3 6.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.3 18.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.3 3.8 GO:0044393 microspike(GO:0044393)
1.3 18.9 GO:0005916 fascia adherens(GO:0005916)
1.1 11.2 GO:0045180 basal cortex(GO:0045180)
1.1 14.4 GO:0035253 ciliary rootlet(GO:0035253)
1.0 5.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.0 6.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.9 3.7 GO:0036449 microtubule minus-end(GO:0036449)
0.9 3.7 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.9 12.6 GO:0042583 chromaffin granule(GO:0042583)
0.8 13.7 GO:0033270 paranode region of axon(GO:0033270)
0.8 6.2 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.7 3.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.7 6.5 GO:0070652 HAUS complex(GO:0070652)
0.7 10.0 GO:0097227 sperm annulus(GO:0097227)
0.7 10.6 GO:0031045 dense core granule(GO:0031045)
0.6 8.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 2.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.6 4.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.6 5.3 GO:0016013 syntrophin complex(GO:0016013)
0.5 15.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.5 7.0 GO:0043198 dendritic shaft(GO:0043198)
0.5 6.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 1.4 GO:0098536 deuterosome(GO:0098536)
0.4 2.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.4 2.9 GO:0032437 cuticular plate(GO:0032437)
0.4 1.8 GO:0032021 NELF complex(GO:0032021)
0.4 11.9 GO:0000795 synaptonemal complex(GO:0000795)
0.4 8.9 GO:0030027 lamellipodium(GO:0030027)
0.3 2.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 3.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 3.6 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 7.5 GO:0005921 gap junction(GO:0005921)
0.3 55.3 GO:0030426 growth cone(GO:0030426)
0.3 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 1.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 4.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 5.6 GO:0035861 site of double-strand break(GO:0035861)
0.2 13.4 GO:0014704 intercalated disc(GO:0014704)
0.2 5.7 GO:0005605 basal lamina(GO:0005605)
0.2 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 20.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 4.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 13.1 GO:0031594 neuromuscular junction(GO:0031594)
0.2 8.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.6 GO:0031674 I band(GO:0031674)
0.2 1.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 14.2 GO:0045202 synapse(GO:0045202)
0.2 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 9.3 GO:0016235 aggresome(GO:0016235)
0.2 6.3 GO:0016592 mediator complex(GO:0016592)
0.2 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.2 41.7 GO:0060076 excitatory synapse(GO:0060076)
0.2 19.8 GO:0043204 perikaryon(GO:0043204)
0.2 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 4.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 6.1 GO:0001533 cornified envelope(GO:0001533)
0.1 9.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.3 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 8.4 GO:0005902 microvillus(GO:0005902)
0.1 1.3 GO:0030673 axolemma(GO:0030673)
0.1 5.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 3.7 GO:0000786 nucleosome(GO:0000786)
0.1 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.1 9.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 21.8 GO:0030424 axon(GO:0030424)
0.1 38.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 3.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 8.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.9 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 7.4 GO:0005874 microtubule(GO:0005874)
0.1 4.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 2.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 4.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 7.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 2.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.2 GO:0005814 centriole(GO:0005814)
0.0 15.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 19.9 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
2.4 14.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.3 7.0 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
2.3 6.8 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
2.0 6.1 GO:0004947 bradykinin receptor activity(GO:0004947)
1.8 5.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.7 8.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.7 15.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.6 4.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.5 4.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.4 10.0 GO:0031711 bradykinin receptor binding(GO:0031711)
1.4 4.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.3 9.4 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
1.3 20.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.3 5.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.2 3.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.2 3.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.2 8.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 9.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.1 6.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.1 15.0 GO:0030957 Tat protein binding(GO:0030957)
1.0 24.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.0 4.1 GO:0031716 calcitonin receptor binding(GO:0031716)
1.0 4.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.0 4.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.9 3.7 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.9 9.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.8 3.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.8 4.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.8 4.0 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.8 3.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 2.3 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.8 7.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.7 19.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.7 7.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.7 4.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.7 11.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.7 6.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.6 8.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 1.8 GO:0070888 E-box binding(GO:0070888)
0.6 16.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.6 5.7 GO:0042731 PH domain binding(GO:0042731)
0.6 4.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 7.7 GO:1903136 cuprous ion binding(GO:1903136)
0.5 14.0 GO:0031489 myosin V binding(GO:0031489)
0.5 1.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.5 2.1 GO:0035473 lipase binding(GO:0035473)
0.5 42.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 3.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 12.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.5 8.9 GO:0005522 profilin binding(GO:0005522)
0.5 14.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.5 1.9 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 3.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 2.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 0.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.4 1.3 GO:0000995 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.4 3.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 22.3 GO:0042169 SH2 domain binding(GO:0042169)
0.4 2.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 5.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 2.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 5.3 GO:0002162 dystroglycan binding(GO:0002162)
0.4 5.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 6.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 2.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4 1.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 4.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 1.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 8.5 GO:0030507 spectrin binding(GO:0030507)
0.3 4.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 7.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 17.6 GO:0016504 peptidase activator activity(GO:0016504)
0.3 6.9 GO:0003777 microtubule motor activity(GO:0003777)
0.3 7.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 1.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 8.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 8.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 3.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 5.6 GO:0043495 protein anchor(GO:0043495)
0.3 1.5 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.3 3.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 4.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 4.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 11.3 GO:0003785 actin monomer binding(GO:0003785)
0.2 38.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.4 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.2 1.4 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 4.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 19.8 GO:0051213 dioxygenase activity(GO:0051213)
0.2 63.0 GO:0015631 tubulin binding(GO:0015631)
0.2 4.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 4.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 7.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.9 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 18.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 32.8 GO:0051015 actin filament binding(GO:0051015)
0.2 7.6 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.7 GO:0031005 filamin binding(GO:0031005)
0.2 1.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 6.4 GO:0060590 ATPase regulator activity(GO:0060590)
0.1 2.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.9 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 10.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 1.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 13.4 GO:0005179 hormone activity(GO:0005179)
0.1 2.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 4.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 6.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 2.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 6.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 4.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 5.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 6.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.0 GO:0043022 ribosome binding(GO:0043022)
0.1 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 5.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 2.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 3.6 GO:0031072 heat shock protein binding(GO:0031072)
0.0 10.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.6 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 12.5 GO:0005525 GTP binding(GO:0005525)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 4.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 13.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 7.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.6 17.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 16.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.6 26.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.5 22.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 22.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.4 25.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 4.2 ST STAT3 PATHWAY STAT3 Pathway
0.3 4.5 PID IL5 PATHWAY IL5-mediated signaling events
0.3 5.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 11.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 3.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 12.3 PID BARD1 PATHWAY BARD1 signaling events
0.2 9.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 6.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 4.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 5.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 2.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 4.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 8.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 11.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 5.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 5.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.8 PID IL3 PATHWAY IL3-mediated signaling events
0.1 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 19.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 3.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 19.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
1.0 25.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
1.0 18.3 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.0 19.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.9 24.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.8 10.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 8.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 2.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.6 12.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.5 14.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4 10.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 7.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4 6.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.3 6.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 6.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 4.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 8.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 4.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 10.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 18.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.3 3.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.2 6.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 8.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 2.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 4.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 34.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 7.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 9.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 3.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 8.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 2.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 4.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 5.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 8.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 6.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 9.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 6.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 2.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.8 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 3.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 5.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels