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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for KLF13

Z-value: 0.95

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Transcription factors associated with KLF13

Gene Symbol Gene ID Gene Info
KLF13
ENSG00000169926.5 Kruppel like factor 13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF13hg19_v2_chr15_+_31619013_316190950.335.6e-07Click!

Activity profile of KLF13 motif

Sorted Z-values of KLF13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_15756382 19.33 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr14_-_74551096 15.11 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr19_+_45349432 14.67 ENST00000252485.4
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr6_-_31125850 13.89 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
CCHCR1
coiled-coil alpha-helical rod protein 1
chr14_-_74551172 13.16 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr19_+_49867181 12.55 ENST00000597546.1
DKKL1
dickkopf-like 1
chr19_+_49866851 11.97 ENST00000221498.2
ENST00000596402.1
DKKL1
dickkopf-like 1
chr7_+_99775520 11.26 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3
stromal antigen 3
chr7_+_99775366 11.25 ENST00000394018.2
ENST00000416412.1
STAG3
stromal antigen 3
chr19_+_49866331 11.24 ENST00000597873.1
DKKL1
dickkopf-like 1
chr6_-_33285505 11.11 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr6_+_41040678 11.05 ENST00000341376.6
ENST00000353205.5
NFYA
nuclear transcription factor Y, alpha
chr10_+_104678102 10.38 ENST00000433628.2
CNNM2
cyclin M2
chr19_-_50311896 10.28 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr17_+_7184986 10.10 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr19_-_10764509 9.97 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr12_+_58013693 9.78 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr17_-_6915646 9.58 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr17_+_27055798 9.40 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr10_+_104678032 9.01 ENST00000369878.4
ENST00000369875.3
CNNM2
cyclin M2
chrX_-_103401649 8.77 ENST00000357421.4
SLC25A53
solute carrier family 25, member 53
chr1_+_45805728 8.64 ENST00000539779.1
TOE1
target of EGR1, member 1 (nuclear)
chr15_+_28623784 8.61 ENST00000526619.2
ENST00000337838.7
ENST00000532622.2
GOLGA8F
golgin A8 family, member F
chr5_+_178450753 8.58 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
ZNF879
zinc finger protein 879
chr15_-_28778117 8.36 ENST00000525590.2
ENST00000329523.6
GOLGA8G
golgin A8 family, member G
chr16_-_28936493 8.33 ENST00000544477.1
ENST00000357573.6
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr17_+_42264322 7.95 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr14_+_23299088 7.94 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr18_-_56940611 7.79 ENST00000256852.7
ENST00000334889.3
RAX
retina and anterior neural fold homeobox
chr19_+_41284121 7.78 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr17_+_74733744 7.52 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
MFSD11
major facilitator superfamily domain containing 11
chr2_-_73053126 7.35 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr12_-_113772835 7.20 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr7_-_99756293 7.16 ENST00000316937.3
ENST00000456769.1
C7orf43
chromosome 7 open reading frame 43
chr19_-_12886327 7.07 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr4_+_55524085 7.04 ENST00000412167.2
ENST00000288135.5
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr10_+_102672712 6.92 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr17_+_42264395 6.87 ENST00000587989.1
ENST00000590235.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr11_+_65479702 6.86 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
KAT5
K(lysine) acetyltransferase 5
chr12_-_124457257 6.68 ENST00000545891.1
CCDC92
coiled-coil domain containing 92
chr16_+_84853580 6.68 ENST00000262424.5
ENST00000566151.1
ENST00000567845.1
ENST00000564567.1
ENST00000569090.1
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr21_+_44313375 6.67 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr12_-_124457371 6.60 ENST00000238156.3
ENST00000545037.1
CCDC92
coiled-coil domain containing 92
chr15_+_23255242 6.56 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr5_+_170288856 6.56 ENST00000523189.1
RANBP17
RAN binding protein 17
chr17_-_36956155 6.33 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr19_+_36249057 6.32 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr11_-_72145641 6.32 ENST00000538039.1
ENST00000445069.2
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr11_-_59383617 6.17 ENST00000263847.1
OSBP
oxysterol binding protein
chr20_-_44600810 6.16 ENST00000322927.2
ENST00000426788.1
ZNF335
zinc finger protein 335
chr19_+_5455421 6.11 ENST00000222033.4
ZNRF4
zinc and ring finger 4
chr3_-_149470229 6.07 ENST00000473414.1
COMMD2
COMM domain containing 2
chr7_+_111846741 6.06 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
ZNF277
zinc finger protein 277
chr13_+_27131798 5.91 ENST00000361042.4
WASF3
WAS protein family, member 3
chr18_-_51750948 5.74 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr6_+_30594619 5.65 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
ATAT1
alpha tubulin acetyltransferase 1
chr19_-_47164386 5.53 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr9_+_132597722 5.53 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
USP20
ubiquitin specific peptidase 20
chr1_+_150898812 5.39 ENST00000271640.5
ENST00000448029.1
ENST00000368962.2
ENST00000534805.1
ENST00000368969.4
ENST00000368963.1
ENST00000498193.1
SETDB1
SET domain, bifurcated 1
chr11_-_72145669 5.38 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr13_+_27131887 5.25 ENST00000335327.5
WASF3
WAS protein family, member 3
chr21_+_48055527 5.23 ENST00000397638.2
ENST00000458387.2
ENST00000451211.2
ENST00000291705.6
ENST00000397637.1
ENST00000334494.4
ENST00000397628.1
ENST00000440086.1
PRMT2
protein arginine methyltransferase 2
chr13_+_24734880 5.19 ENST00000382095.4
SPATA13
spermatogenesis associated 13
chr12_-_6580094 5.18 ENST00000361716.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr6_+_106534192 5.12 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_45805752 5.07 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
MUTYH
mutY homolog
chr5_-_32313082 5.07 ENST00000382142.3
MTMR12
myotubularin related protein 12
chr17_-_40333150 5.03 ENST00000264661.3
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_-_7041466 4.97 ENST00000536068.1
ENST00000278314.4
ZNF214
zinc finger protein 214
chr13_-_30424821 4.93 ENST00000380680.4
UBL3
ubiquitin-like 3
chr3_+_50606901 4.92 ENST00000455834.1
HEMK1
HemK methyltransferase family member 1
chr1_+_33352036 4.88 ENST00000373467.3
HPCA
hippocalcin
chr1_-_45805667 4.82 ENST00000488731.2
ENST00000435155.1
MUTYH
mutY homolog
chr12_-_6579808 4.81 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr11_+_49050504 4.72 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr9_+_35605274 4.57 ENST00000336395.5
TESK1
testis-specific kinase 1
chr12_-_48152853 4.56 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr1_-_45805607 4.56 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
MUTYH
mutY homolog
chr19_+_39616410 4.53 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr3_+_184529929 4.47 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr17_+_42264556 4.47 ENST00000319511.6
ENST00000589785.1
ENST00000592825.1
ENST00000589184.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr2_-_241500447 4.42 ENST00000536462.1
ENST00000405002.1
ENST00000441168.1
ENST00000403283.1
ANKMY1
ankyrin repeat and MYND domain containing 1
chrX_-_140271249 4.41 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr1_-_45806053 4.40 ENST00000412971.1
ENST00000372098.3
ENST00000372110.3
ENST00000529984.1
ENST00000528332.2
ENST00000372115.3
ENST00000450313.1
MUTYH
mutY homolog
chr1_+_15573757 4.39 ENST00000358897.4
ENST00000417793.1
ENST00000375999.3
ENST00000433640.2
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr19_-_7936344 4.36 ENST00000599142.1
CTD-3193O13.9
Protein FLJ22184
chr6_+_28109703 4.34 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr11_+_44587141 4.33 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82
CD82 molecule
chr12_+_6982725 4.32 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr14_+_68286516 4.28 ENST00000471583.1
ENST00000487270.1
ENST00000488612.1
RAD51B
RAD51 paralog B
chr3_+_50606577 4.22 ENST00000434410.1
ENST00000232854.4
HEMK1
HemK methyltransferase family member 1
chr4_+_699610 4.20 ENST00000521023.2
PCGF3
polycomb group ring finger 3
chr7_-_19748640 4.19 ENST00000222567.5
TWISTNB
TWIST neighbor
chr1_-_23810664 4.13 ENST00000336689.3
ENST00000437606.2
ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr12_+_112563303 4.12 ENST00000412615.2
TRAFD1
TRAF-type zinc finger domain containing 1
chr9_-_35111570 4.07 ENST00000378561.1
ENST00000603301.1
FAM214B
family with sequence similarity 214, member B
chr1_-_223316611 4.06 ENST00000366881.1
TLR5
toll-like receptor 5
chr20_+_48599506 4.00 ENST00000244050.2
SNAI1
snail family zinc finger 1
chr3_+_184529948 3.99 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr19_-_19843900 3.98 ENST00000344099.3
ZNF14
zinc finger protein 14
chr14_+_24867992 3.96 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr17_+_19281034 3.94 ENST00000308406.5
ENST00000299612.7
MAPK7
mitogen-activated protein kinase 7
chrX_-_13062752 3.92 ENST00000380625.3
ENST00000542843.1
FAM9C
family with sequence similarity 9, member C
chr1_+_45805342 3.90 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr4_+_1795012 3.85 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3
fibroblast growth factor receptor 3
chr9_-_131038266 3.78 ENST00000490628.1
ENST00000421699.2
ENST00000450617.1
GOLGA2
golgin A2
chr2_+_239335449 3.78 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr19_-_6767516 3.68 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr19_+_49713991 3.65 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr10_+_120789223 3.63 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr5_-_32313019 3.58 ENST00000280285.5
ENST00000264934.5
MTMR12
myotubularin related protein 12
chr15_+_41851211 3.39 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr12_+_112563335 3.38 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1
TRAF-type zinc finger domain containing 1
chr9_-_116163400 3.36 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr16_+_4897912 3.33 ENST00000545171.1
UBN1
ubinuclein 1
chr7_+_100209725 3.28 ENST00000223054.4
MOSPD3
motile sperm domain containing 3
chr2_-_97405775 3.22 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L
lectin, mannose-binding 2-like
chr10_+_115803650 3.19 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr21_-_34100341 3.17 ENST00000382499.2
ENST00000433931.2
SYNJ1
synaptojanin 1
chr1_-_25558984 3.15 ENST00000236273.4
SYF2
SYF2 pre-mRNA-splicing factor
chr3_+_152552685 3.05 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr19_+_10764937 2.97 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr21_-_34100244 2.97 ENST00000382491.3
ENST00000357345.3
ENST00000429236.1
SYNJ1
synaptojanin 1
chr9_-_35111420 2.96 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr19_-_14629224 2.91 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_-_111846435 2.86 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr7_+_100210133 2.85 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr19_-_6767431 2.70 ENST00000437152.3
ENST00000597687.1
SH2D3A
SH2 domain containing 3A
chr11_-_89540388 2.59 ENST00000532501.2
TRIM49
tripartite motif containing 49
chr19_-_46142637 2.58 ENST00000590043.1
ENST00000589876.1
EML2
echinoderm microtubule associated protein like 2
chr2_-_110371664 2.56 ENST00000545389.1
ENST00000423520.1
SEPT10
septin 10
chr21_-_33765303 2.55 ENST00000382751.3
URB1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr7_+_86273218 2.52 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr7_+_100209979 2.48 ENST00000493970.1
ENST00000379527.2
MOSPD3
motile sperm domain containing 3
chr19_-_9420249 2.40 ENST00000591998.1
ZNF699
zinc finger protein 699
chr19_-_46142680 2.38 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr12_-_6579833 2.32 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr20_+_37590942 2.30 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr7_+_33169142 2.25 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
BBS9
Bardet-Biedl syndrome 9
chr16_-_89883015 2.17 ENST00000563673.1
ENST00000389301.3
ENST00000568369.1
ENST00000534992.1
ENST00000389302.3
ENST00000543736.1
FANCA
Fanconi anemia, complementation group A
chr15_-_80215984 2.13 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr7_+_100450328 2.12 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
SLC12A9
solute carrier family 12, member 9
chr17_-_7165662 2.09 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr19_-_2151523 2.02 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1
adaptor-related protein complex 3, delta 1 subunit
chr19_+_10765003 1.98 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr9_-_77567743 1.90 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr6_+_28193037 1.85 ENST00000531981.1
ENST00000425468.2
ENST00000252207.5
ENST00000531979.1
ENST00000527436.1
ZSCAN9
zinc finger and SCAN domain containing 9
chr9_-_131038214 1.81 ENST00000609374.1
GOLGA2
golgin A2
chr7_+_29234028 1.80 ENST00000222792.6
CHN2
chimerin 2
chr15_-_26874230 1.78 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr15_-_74374891 1.73 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr19_+_1071203 1.67 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr15_+_83098710 1.65 ENST00000561062.1
ENST00000358583.3
GOLGA6L9
golgin A6 family-like 20
chr20_+_60813535 1.64 ENST00000358053.2
ENST00000313733.3
ENST00000439951.2
OSBPL2
oxysterol binding protein-like 2
chr15_+_84904525 1.64 ENST00000510439.2
GOLGA6L4
golgin A6 family-like 4
chr19_+_7985198 1.62 ENST00000221573.6
ENST00000595637.1
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr6_+_33378738 1.53 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr17_-_5487277 1.52 ENST00000572272.1
ENST00000354411.3
ENST00000577119.1
NLRP1
NLR family, pyrin domain containing 1
chr10_+_72164135 1.49 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr2_-_8977714 1.46 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
KIDINS220
kinase D-interacting substrate, 220kDa
chr17_+_79679369 1.46 ENST00000350690.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr19_+_45504688 1.44 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr6_+_31588478 1.36 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr14_+_54976546 1.29 ENST00000216420.7
CGRRF1
cell growth regulator with ring finger domain 1
chr15_+_82722225 1.13 ENST00000300515.8
GOLGA6L9
golgin A6 family-like 9
chr2_-_8723918 1.08 ENST00000454224.1
AC011747.4
AC011747.4
chr19_+_44100544 1.05 ENST00000391965.2
ENST00000525771.1
ZNF576
zinc finger protein 576
chr6_-_41040268 1.00 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr4_+_699537 0.99 ENST00000419774.1
ENST00000362003.5
ENST00000400151.2
ENST00000427463.1
ENST00000470161.2
PCGF3
polycomb group ring finger 3
chr17_+_79679299 0.96 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_132129151 0.96 ENST00000360971.2
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr21_+_44394742 0.93 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr17_+_38296576 0.90 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr5_+_148206156 0.86 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr17_-_77770830 0.85 ENST00000269385.4
CBX8
chromobox homolog 8
chr19_+_44100727 0.77 ENST00000528387.1
ENST00000529930.1
ENST00000336564.4
ENST00000607544.1
ENST00000526798.1
ZNF576
SRRM5
zinc finger protein 576
serine/arginine repetitive matrix 5
chr6_-_11779403 0.66 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr11_+_129939779 0.66 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2
amyloid beta (A4) precursor-like protein 2
chr17_+_17380294 0.62 ENST00000268711.3
ENST00000580462.1
MED9
mediator complex subunit 9
chr15_-_30685752 0.57 ENST00000299847.2
ENST00000397827.3
CHRFAM7A
CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
chr19_+_50887585 0.53 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1
polymerase (DNA directed), delta 1, catalytic subunit
chr17_-_5487768 0.53 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLRP1
NLR family, pyrin domain containing 1
chr19_-_44100275 0.53 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr20_-_44539538 0.42 ENST00000372420.1
PLTP
phospholipid transfer protein
chr4_-_13546632 0.39 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr2_-_110371412 0.35 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
SEPT10
septin 10
chr15_+_41056218 0.27 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr14_+_23067146 0.27 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr21_+_44394620 0.27 ENST00000291547.5
PKNOX1
PBX/knotted 1 homeobox 1
chr11_-_6426635 0.22 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr6_-_2962331 0.21 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr15_-_74988281 0.16 ENST00000566828.1
ENST00000563009.1
ENST00000568176.1
ENST00000566243.1
ENST00000566219.1
ENST00000426797.3
ENST00000566119.1
ENST00000315127.4
EDC3
enhancer of mRNA decapping 3
chr16_-_3074231 0.14 ENST00000572355.1
ENST00000248089.3
ENST00000574980.1
ENST00000354679.3
ENST00000396916.1
ENST00000573842.1
HCFC1R1
host cell factor C1 regulator 1 (XPO1 dependent)
chr20_-_8000426 0.13 ENST00000527925.1
ENST00000246024.2
TMX4
thioredoxin-related transmembrane protein 4
chr11_+_123986069 0.11 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr7_+_99102267 0.09 ENST00000326775.5
ENST00000451158.1
ZKSCAN5
zinc finger with KRAB and SCAN domains 5

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 28.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.7 18.8 GO:0045007 depurination(GO:0045007)
2.6 10.3 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
2.3 7.0 GO:0048170 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162) positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.5 6.1 GO:1904978 regulation of endosome organization(GO:1904978)
1.4 8.5 GO:0030820 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
1.4 9.8 GO:0019532 oxalate transport(GO:0019532)
1.4 19.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
1.4 4.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
1.4 4.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.3 22.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.1 3.4 GO:0070541 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
1.1 5.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.0 12.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
1.0 5.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
1.0 4.9 GO:1902075 cellular response to salt(GO:1902075)
0.9 3.7 GO:1904199 positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.9 7.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 9.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.8 8.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.8 2.4 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.8 4.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.7 5.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 4.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.7 5.6 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.7 12.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.7 2.0 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.7 5.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.6 5.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.6 3.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.6 2.9 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.6 5.7 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.6 35.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.5 6.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.4 6.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.4 2.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 5.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.4 21.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.4 11.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.4 6.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.4 10.1 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 4.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.3 4.0 GO:0015074 DNA integration(GO:0015074)
0.3 6.9 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.3 1.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 20.4 GO:0006611 protein export from nucleus(GO:0006611)
0.3 5.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 3.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 7.8 GO:0021854 hypothalamus development(GO:0021854)
0.2 2.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 3.6 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 8.6 GO:1901998 toxin transport(GO:1901998)
0.2 3.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 2.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 7.1 GO:0008333 endosome to lysosome transport(GO:0008333)
0.2 1.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 7.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 9.8 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 7.5 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 3.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 3.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 6.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.1 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 4.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 7.8 GO:0046323 glucose import(GO:0046323)
0.1 2.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 3.3 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 5.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 9.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 4.1 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 2.2 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 9.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 1.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 6.4 GO:0007254 JNK cascade(GO:0007254)
0.0 3.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.9 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 8.4 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 4.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 6.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.2 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 5.7 GO:0007507 heart development(GO:0007507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 22.5 GO:0030893 meiotic cohesin complex(GO:0030893)
2.2 17.9 GO:0032593 insulin-responsive compartment(GO:0032593)
1.8 7.1 GO:0070695 FHF complex(GO:0070695)
1.7 5.2 GO:0035189 Rb-E2F complex(GO:0035189)
1.7 6.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.7 8.5 GO:0033263 CORVET complex(GO:0033263)
1.0 7.2 GO:0030061 mitochondrial crista(GO:0030061)
1.0 11.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 5.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.7 4.3 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 5.7 GO:0097427 microtubule bundle(GO:0097427)
0.4 4.9 GO:0044327 dendritic spine head(GO:0044327)
0.4 3.9 GO:0000800 lateral element(GO:0000800)
0.3 2.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 2.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 6.4 GO:0000145 exocyst(GO:0000145)
0.2 2.2 GO:0034464 BBSome(GO:0034464)
0.2 4.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 20.5 GO:0043195 terminal bouton(GO:0043195)
0.2 9.4 GO:0097546 ciliary base(GO:0097546)
0.2 23.8 GO:0005814 centriole(GO:0005814)
0.2 7.0 GO:0042629 mast cell granule(GO:0042629)
0.2 12.5 GO:0015030 Cajal body(GO:0015030)
0.1 3.7 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 7.6 GO:0031519 PcG protein complex(GO:0031519)
0.1 6.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 3.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 2.9 GO:0032420 stereocilium(GO:0032420)
0.1 39.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 6.6 GO:0005643 nuclear pore(GO:0005643)
0.1 6.3 GO:0005776 autophagosome(GO:0005776)
0.1 5.0 GO:0072686 mitotic spindle(GO:0072686)
0.1 18.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 16.3 GO:0030027 lamellipodium(GO:0030027)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 5.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 4.6 GO:0016605 PML body(GO:0016605)
0.0 11.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 6.3 GO:0005769 early endosome(GO:0005769)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)
0.0 19.4 GO:0005739 mitochondrion(GO:0005739)
0.0 23.7 GO:0005615 extracellular space(GO:0005615)
0.0 6.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.8 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.1 6.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.6 9.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.5 6.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.4 19.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.4 4.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.1 19.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.1 28.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.1 5.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.1 5.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.1 5.5 GO:0070097 delta-catenin binding(GO:0070097)
0.9 6.2 GO:0008142 oxysterol binding(GO:0008142)
0.8 5.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.8 2.4 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.8 3.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.7 10.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 7.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.7 2.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.6 10.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.6 6.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 5.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.5 2.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.4 4.3 GO:0000150 recombinase activity(GO:0000150)
0.4 3.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 4.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 1.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 10.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.3 7.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.3 12.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 4.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 12.5 GO:0017069 snRNA binding(GO:0017069)
0.2 5.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 4.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 2.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 3.2 GO:0005537 mannose binding(GO:0005537)
0.1 4.9 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 6.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 9.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 6.9 GO:0050681 androgen receptor binding(GO:0050681)
0.1 20.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 7.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 2.1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 3.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 3.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0003696 satellite DNA binding(GO:0003696)
0.1 8.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.9 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 3.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 4.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 5.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 5.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 12.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 6.7 GO:0008201 heparin binding(GO:0008201)
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 6.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0001047 core promoter binding(GO:0001047)
0.0 7.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 7.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 10.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 10.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 4.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 3.9 ST GA12 PATHWAY G alpha 12 Pathway
0.2 4.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 8.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 5.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 11.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 6.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 7.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 7.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 11.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.9 PID FGF PATHWAY FGF signaling pathway
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 6.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 4.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 19.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.0 28.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.0 18.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.8 11.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 10.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.5 14.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 12.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 3.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 12.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 22.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 7.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 4.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 6.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 4.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 3.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 5.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 4.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 4.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 6.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 2.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.9 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 6.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 4.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 8.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 3.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease