GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
LHX6 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000106852.11	LIM homeobox 6

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LHX6	hg19_v2_chr9_-_124989804_124989865, hg19_v2_chr9_-_124991124_124991246	0.50	5.6e-15	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_204380919 Show fit	21.56	ENST00000367188.4	PPP1R15B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory subunit 15B
chr12_-_45269430 Show fit	12.92	ENST00000395487.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr11_-_76155618 Show fit	12.81	ENST00000530759.1	RP11-111M22.3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-111M22.3
chr6_-_167040731 Show fit	12.29	ENST00000265678.4	RPS6KA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_45270151 Show fit	12.28	ENST00000429094.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr12_-_45270077 Show fit	12.13	ENST00000551601.1 ENST00000549027.1 ENST00000452445.2	NELL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr11_-_76155700 Show fit	12.12	ENST00000572035.1	RP11-111M22.3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-111M22.3
chr17_+_74733744 Show fit	12.01	ENST00000586689.1 ENST00000587661.1 ENST00000593181.1 ENST00000336509.4 ENST00000355954.3	MFSD11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major facilitator superfamily domain containing 11
chr12_-_91546926 Show fit	11.99	ENST00000550758.1	DCN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr6_-_32095968 Show fit	11.32	ENST00000375203.3 ENST00000375201.4	ATF6B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	activating transcription factor 6 beta
chr17_-_1532106 Show fit	10.77	ENST00000301335.5 ENST00000382147.4	SLC43A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 43 (amino acid system L transporter), member 2
chrX_-_47509887 Show fit	10.51	ENST00000247161.3 ENST00000592066.1 ENST00000376983.3	ELK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELK1, member of ETS oncogene family
chr19_-_19302931 Show fit	10.47	ENST00000444486.3 ENST00000514819.3 ENST00000585679.1 ENST00000162023.5	MEF2BNB-MEF2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit MEF2BNB Links Ensembl NCBI GeneCards UniProt NextProt Show fit MEF2B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MEF2BNB-MEF2B readthrough MEF2B neighbor myocyte enhancer factor 2B
chr10_-_28571015 Show fit	9.79	ENST00000375719.3 ENST00000375732.1	MPP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_-_13390765 Show fit	9.59	ENST00000357367.2	PRAMEF8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRAME family member 8
chr17_+_73452695 Show fit	9.52	ENST00000582186.1 ENST00000582455.1 ENST00000581252.1 ENST00000579208.1	KIAA0195 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0195
chr17_-_41466555 Show fit	8.66	ENST00000586231.1	LINC00910 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 910
chr1_+_44115814 Show fit	8.24	ENST00000372396.3	KDM4A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 4A
chr5_+_66300446 Show fit	8.22	ENST00000261569.7	MAST4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated serine/threonine kinase family member 4
chr1_+_28261533 Show fit	8.19	ENST00000411604.1 ENST00000373888.4	SMPDL3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sphingomyelin phosphodiesterase, acid-like 3B
chr10_-_104001231 Show fit	8.09	ENST00000370002.3	PITX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired-like homeodomain 3
chr6_-_62996066 Show fit	7.99	ENST00000281156.4	KHDRBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH domain containing, RNA binding, signal transduction associated 2
chr14_-_52535712 Show fit	7.57	ENST00000216286.5 ENST00000541773.1	NID2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nidogen 2 (osteonidogen)
chr16_-_55866997 Show fit	7.55	ENST00000360526.3 ENST00000361503.4	CES1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carboxylesterase 1
chr3_+_115342349 Show fit	7.51	ENST00000393780.3	GAP43 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth associated protein 43
chr11_+_76156045 Show fit	7.38	ENST00000533988.1 ENST00000524490.1 ENST00000334736.3 ENST00000343878.3 ENST00000533972.1	C11orf30 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 11 open reading frame 30
chr22_+_41777927 Show fit	7.28	ENST00000266304.4	TEF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyrotrophic embryonic factor
chr6_-_31125850 Show fit	7.18	ENST00000507751.1 ENST00000448162.2 ENST00000502557.1 ENST00000503420.1 ENST00000507892.1 ENST00000507226.1 ENST00000513222.1 ENST00000503934.1 ENST00000396263.2 ENST00000508683.1 ENST00000428174.1 ENST00000448141.2 ENST00000507829.1 ENST00000455279.2 ENST00000376266.5	CCHCR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil alpha-helical rod protein 1
chr2_-_201936302 Show fit	6.86	ENST00000453765.1 ENST00000452799.1 ENST00000446678.1 ENST00000418596.3	FAM126B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 126, member B
chr4_-_121843985 Show fit	6.84	ENST00000264808.3 ENST00000428209.2 ENST00000515109.1 ENST00000394435.2	PRDM5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PR domain containing 5
chr11_+_5710919 Show fit	6.79	ENST00000379965.3 ENST00000425490.1	TRIM22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 22
chr13_+_37006421 Show fit	6.63	ENST00000255465.4	CCNA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin A1
chr14_+_100842735 Show fit	6.59	ENST00000554998.1 ENST00000402312.3 ENST00000335290.6 ENST00000554175.1	WDR25 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 25
chr4_+_89513574 Show fit	6.58	ENST00000402738.1 ENST00000431413.1 ENST00000422770.1 ENST00000407637.1	HERC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_+_76127529 Show fit	6.56	ENST00000556977.1 ENST00000557636.1 ENST00000286650.5 ENST00000298832.9	TTLL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin tyrosine ligase-like family, member 5
chr16_+_6533380 Show fit	6.55	ENST00000552089.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_-_53258314 Show fit	6.46	ENST00000216410.3 ENST00000557604.1	GNPNAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glucosamine-phosphate N-acetyltransferase 1
chr13_+_37006398 Show fit	6.45	ENST00000418263.1	CCNA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin A1
chr17_-_44657017 Show fit	6.37	ENST00000573185.1 ENST00000570550.1 ENST00000445552.2 ENST00000336125.5 ENST00000329240.4 ENST00000337845.7	ARL17A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 17A
chr2_+_113763031 Show fit	5.94	ENST00000259211.6	IL36A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 36, alpha
chr2_-_152118352 Show fit	5.86	ENST00000331426.5	RBM43 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 43
chr19_-_12833361 Show fit	5.81	ENST00000592287.1	TNPO2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transportin 2
chr16_+_6533729 Show fit	5.80	ENST00000551752.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_3521518 Show fit	5.75	ENST00000382093.5	ADI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acireductone dioxygenase 1
chr12_+_7014064 Show fit	5.66	ENST00000443597.2	LRRC23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 23
chr17_-_44439084 Show fit	5.66	ENST00000575960.1 ENST00000575698.1 ENST00000571246.1 ENST00000434041.2 ENST00000570618.1 ENST00000450673.3	ARL17B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 17B
chr6_-_33285505 Show fit	5.42	ENST00000431845.2	ZBTB22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 22
chr14_-_104181771 Show fit	5.42	ENST00000554913.1 ENST00000554974.1 ENST00000553361.1 ENST00000555055.1 ENST00000555964.1 ENST00000556682.1 ENST00000445556.1 ENST00000553332.1 ENST00000352127.7	XRCC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 3
chr18_-_65184217 Show fit	5.28	ENST00000310045.7	DSEL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dermatan sulfate epimerase-like
chr5_-_54830871 Show fit	5.27	ENST00000307259.8	PPAP2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidic acid phosphatase type 2A
chr16_+_55512742 Show fit	5.22	ENST00000568715.1 ENST00000219070.4	MMP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_+_7013897 Show fit	5.16	ENST00000007969.8 ENST00000323702.5	LRRC23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 23
chr8_+_9413410 Show fit	5.06	ENST00000520408.1 ENST00000310430.6 ENST00000522110.1	TNKS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr19_-_10121144 Show fit	5.02	ENST00000264828.3	COL5A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type V, alpha 3
chr3_+_67705121 Show fit	5.00	ENST00000464420.1 ENST00000482677.1	RP11-81N13.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-81N13.1
chr17_+_80416482 Show fit	4.87	ENST00000309794.11 ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1	NARF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear prelamin A recognition factor
chr14_+_99947715 Show fit	4.80	ENST00000389879.5 ENST00000557441.1 ENST00000555049.1 ENST00000555842.1	CCNK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin K
chr11_-_35287243 Show fit	4.75	ENST00000464522.2	SLC1A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_104182061 Show fit	4.75	ENST00000216602.6	ZFYVE21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, FYVE domain containing 21
chr14_+_104182105 Show fit	4.75	ENST00000311141.2	ZFYVE21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger, FYVE domain containing 21
chr11_-_133826852 Show fit	4.73	ENST00000533871.2 ENST00000321016.8	IGSF9B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily, member 9B
chr1_+_145438469 Show fit	4.67	ENST00000369317.4	TXNIP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thioredoxin interacting protein
chr18_+_5238549 Show fit	4.61	ENST00000580684.1	LINC00667 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 667
chr18_+_5238055 Show fit	4.60	ENST00000582363.1 ENST00000582008.1 ENST00000580082.1	LINC00667 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 667
chr11_-_236326 Show fit	4.59	ENST00000525237.1 ENST00000532956.1 ENST00000525319.1 ENST00000524564.1 ENST00000382743.4	SIRT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sirtuin 3
chr12_-_56753858 Show fit	4.58	ENST00000314128.4 ENST00000557235.1 ENST00000418572.2	STAT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducer and activator of transcription 2, 113kDa
chr12_+_7014126 Show fit	4.57	ENST00000415834.1 ENST00000436789.1	LRRC23 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 23
chr16_-_66584059 Show fit	4.55	ENST00000417693.3 ENST00000544898.1 ENST00000569718.1 ENST00000527284.1 ENST00000299697.7 ENST00000451102.2	TK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymidine kinase 2, mitochondrial
chr3_-_105587879 Show fit	4.53	ENST00000264122.4 ENST00000403724.1 ENST00000405772.1	CBLB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_-_9760482 Show fit	4.53	ENST00000229402.3	KLRB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	killer cell lectin-like receptor subfamily B, member 1
chr10_-_123274693 Show fit	4.50	ENST00000429361.1	FGFR2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor receptor 2
chr5_-_54830784 Show fit	4.39	ENST00000264775.5	PPAP2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidic acid phosphatase type 2A
chr17_+_72772621 Show fit	4.35	ENST00000335464.5 ENST00000417024.2 ENST00000578764.1 ENST00000582773.1 ENST00000582330.1	TMEM104 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 104
chr6_-_49681235 Show fit	4.33	ENST00000339139.4	CRISP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine-rich secretory protein 2
chr7_+_100209725 Show fit	4.20	ENST00000223054.4	MOSPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	motile sperm domain containing 3
chrX_+_77166172 Show fit	4.19	ENST00000343533.5 ENST00000350425.4 ENST00000341514.6	ATP7A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, Cu++ transporting, alpha polypeptide
chr11_-_128894053 Show fit	4.18	ENST00000392657.3	ARHGAP32 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 32
chr5_-_112630598 Show fit	4.15	ENST00000302475.4	MCC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mutated in colorectal cancers
chr7_+_149571045 Show fit	4.14	ENST00000479613.1 ENST00000606024.1 ENST00000464662.1 ENST00000425642.2	ATP6V0E2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase, H+ transporting V0 subunit e2
chr9_+_71944241 Show fit	3.97	ENST00000257515.8	FAM189A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 189, member A2
chr18_-_21017817 Show fit	3.92	ENST00000542162.1 ENST00000383233.3 ENST00000582336.1 ENST00000450466.2 ENST00000578520.1 ENST00000399707.1	TMEM241 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 241
chr13_-_46626847 Show fit	3.92	ENST00000242848.4 ENST00000282007.3	ZC3H13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CCCH-type containing 13
chr1_-_236228403 Show fit	3.86	ENST00000366595.3	NID1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nidogen 1
chr15_-_77712477 Show fit	3.85	ENST00000560626.2	PEAK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pseudopodium-enriched atypical kinase 1
chrX_-_6453159 Show fit	3.83	ENST00000381089.3 ENST00000398729.1	VCX3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	variable charge, X-linked 3A
chr13_+_37005967 Show fit	3.82	ENST00000440264.1 ENST00000449823.1	CCNA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin A1
chr16_-_55867146 Show fit	3.73	ENST00000422046.2	CES1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carboxylesterase 1
chr1_-_236228417 Show fit	3.72	ENST00000264187.6	NID1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nidogen 1
chr10_-_72142345 Show fit	3.71	ENST00000373224.1 ENST00000446961.1 ENST00000358141.2 ENST00000357631.2	LRRC20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 20
chr19_-_53400813 Show fit	3.66	ENST00000595635.1 ENST00000594741.1 ENST00000597111.1 ENST00000593618.1 ENST00000597909.1	ZNF320 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 320
chr7_-_121784285 Show fit	3.64	ENST00000417368.2	AASS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aminoadipate-semialdehyde synthase
chr10_+_13142225 Show fit	3.61	ENST00000378747.3	OPTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	optineurin
chr10_-_99447024 Show fit	3.60	ENST00000370626.3	AVPI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	arginine vasopressin-induced 1
chr1_+_62439037 Show fit	3.59	ENST00000545929.1	INADL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	InaD-like (Drosophila)
chr2_-_242089677 Show fit	3.57	ENST00000405260.1	PASK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PAS domain containing serine/threonine kinase
chr20_+_54967409 Show fit	3.55	ENST00000415828.1 ENST00000217109.4 ENST00000428552.1	CSTF1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr11_+_7110165 Show fit	3.53	ENST00000306904.5	RBMXL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein, X-linked-like 2
chr4_+_74275057 Show fit	3.52	ENST00000511370.1	ALB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	albumin
chr2_+_220143989 Show fit	3.48	ENST00000336576.5	DNAJB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 2
chr6_+_160542870 Show fit	3.43	ENST00000324965.4 ENST00000457470.2	SLC22A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 22 (organic cation transporter), member 1
chr14_+_22293618 Show fit	3.36	ENST00000390432.2	TRAV10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	T cell receptor alpha variable 10
chr7_+_100210133 Show fit	3.27	ENST00000393950.2 ENST00000424091.2	MOSPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	motile sperm domain containing 3
chr17_+_80416050 Show fit	3.27	ENST00000579198.1 ENST00000390006.4 ENST00000580296.1	NARF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear prelamin A recognition factor
chr16_-_66583701 Show fit	3.25	ENST00000527800.1 ENST00000525974.1 ENST00000563369.2	TK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymidine kinase 2, mitochondrial
chr2_+_166095898 Show fit	3.20	ENST00000424833.1 ENST00000375437.2 ENST00000357398.3	SCN2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, voltage-gated, type II, alpha subunit
chr16_+_72088376 Show fit	3.18	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP Links Ensembl NCBI GeneCards UniProt NextProt Show fit HPR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	haptoglobin haptoglobin-related protein
chr7_+_100209979 Show fit	3.13	ENST00000493970.1 ENST00000379527.2	MOSPD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	motile sperm domain containing 3
chr9_+_104161123 Show fit	3.05	ENST00000374861.3 ENST00000339664.2 ENST00000259395.4	ZNF189 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 189
chr1_-_48866517 Show fit	3.04	ENST00000371841.1	SPATA6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis associated 6
chr3_-_160823158 Show fit	3.00	ENST00000392779.2 ENST00000392780.1 ENST00000494173.1	B3GALNT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr19_-_41870026 Show fit	2.89	ENST00000243578.3	B9D2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 protein domain 2
chr7_-_36764142 Show fit	2.89	ENST00000258749.5 ENST00000535891.1	AOAH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr2_+_90077680 Show fit	2.89	ENST00000390270.2	IGKV3D-20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin kappa variable 3D-20
chr1_+_241695670 Show fit	2.88	ENST00000366557.4	KMO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_+_71296204 Show fit	2.80	ENST00000413702.1	MUC7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mucin 7, secreted
chr6_+_26402517 Show fit	2.78	ENST00000414912.2	BTN3A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin, subfamily 3, member A1
chr6_+_160542821 Show fit	2.72	ENST00000366963.4	SLC22A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 22 (organic cation transporter), member 1
chr12_-_95611149 Show fit	2.71	ENST00000549499.1 ENST00000343958.4 ENST00000546711.1	FGD6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FYVE, RhoGEF and PH domain containing 6
chrX_+_100353153 Show fit	2.71	ENST00000423383.1 ENST00000218507.5 ENST00000403304.2 ENST00000435570.1	CENPI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	centromere protein I
chr1_-_13673511 Show fit	2.62	ENST00000344998.3 ENST00000334600.6	PRAMEF14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PRAME family member 14
chr7_-_99277610 Show fit	2.61	ENST00000343703.5 ENST00000222982.4 ENST00000439761.1 ENST00000339843.2	CYP3A5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 3, subfamily A, polypeptide 5
chr6_+_29624758 Show fit	2.59	ENST00000376917.3 ENST00000376902.3 ENST00000533330.2 ENST00000376888.2	MOG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin oligodendrocyte glycoprotein
chr8_+_42010464 Show fit	2.52	ENST00000518421.1 ENST00000174653.3 ENST00000396926.3 ENST00000521280.1 ENST00000522288.1	AP3M2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor-related protein complex 3, mu 2 subunit
chr19_+_12902289 Show fit	2.50	ENST00000302754.4	JUNB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	jun B proto-oncogene
chr3_-_160823040 Show fit	2.47	ENST00000484127.1 ENST00000492353.1 ENST00000473142.1 ENST00000468268.1 ENST00000460353.1 ENST00000320474.4 ENST00000392781.2	B3GALNT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chrX_+_15525426 Show fit	2.44	ENST00000342014.6	BMX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BMX non-receptor tyrosine kinase
chr17_+_73452545 Show fit	2.41	ENST00000314256.7	KIAA0195 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA0195
chr10_+_13141441 Show fit	2.39	ENST00000263036.5	OPTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	optineurin
chr4_+_165675269 Show fit	2.38	ENST00000507311.1	RP11-294O2.2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-294O2.2
chr21_+_35014706 Show fit	2.35	ENST00000399353.1 ENST00000444491.1 ENST00000381318.3	ITSN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intersectin 1 (SH3 domain protein)
chr6_-_27880174 Show fit	2.35	ENST00000303324.2	OR2B2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor, family 2, subfamily B, member 2
chr7_-_87342564 Show fit	2.28	ENST00000265724.3 ENST00000416177.1	ABCB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr6_-_30585009 Show fit	2.23	ENST00000376511.2	PPP1R10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory subunit 10
chr1_+_241695424 Show fit	2.22	ENST00000366558.3 ENST00000366559.4	KMO Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_27677085 Show fit	2.20	ENST00000545334.1 ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6	PPFIBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr1_-_228613026 Show fit	2.20	ENST00000366696.1	HIST3H3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone cluster 3, H3
chr5_-_20575959 Show fit	2.18	ENST00000507958.1	CDH18 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin 18, type 2
chr16_+_2479390 Show fit	2.11	ENST00000397066.4	CCNF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin F
chr3_+_108541545 Show fit	2.08	ENST00000295756.6	TRAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	T cell receptor associated transmembrane adaptor 1
chr7_-_14029515 Show fit	2.04	ENST00000430479.1 ENST00000405218.2 ENST00000343495.5	ETV1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ets variant 1
chr18_-_67624160 Show fit	2.02	ENST00000581982.1 ENST00000280200.4	CD226 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD226 molecule
chr19_-_7694417 Show fit	2.01	ENST00000358368.4 ENST00000534844.1	XAB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	XPA binding protein 2
chr19_+_17858547 Show fit	2.00	ENST00000600676.1 ENST00000600209.1 ENST00000596309.1 ENST00000598539.1 ENST00000597474.1 ENST00000593385.1 ENST00000598067.1 ENST00000593833.1	FCHO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FCH domain only 1
chr10_+_13141585 Show fit	2.00	ENST00000378764.2	OPTN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	optineurin
chr10_+_71562180 Show fit	1.98	ENST00000517713.1 ENST00000522165.1 ENST00000520133.1	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr3_-_99569821 Show fit	1.97	ENST00000487087.1	FILIP1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	filamin A interacting protein 1-like
chr16_+_31885079 Show fit	1.95	ENST00000300870.10 ENST00000394846.3	ZNF267 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 267
chr11_+_117947782 Show fit	1.90	ENST00000522307.1 ENST00000523251.1 ENST00000437212.3 ENST00000522824.1 ENST00000522151.1	TMPRSS4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protease, serine 4
chr1_-_173886491 Show fit	1.88	ENST00000367698.3	SERPINC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr13_-_19755975 Show fit	1.88	ENST00000400113.3	TUBA3C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, alpha 3c
chr14_+_32798547 Show fit	1.87	ENST00000557354.1 ENST00000557102.1 ENST00000557272.1	AKAP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 6
chr6_+_39760129 Show fit	1.86	ENST00000274867.4	DAAM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled associated activator of morphogenesis 2
chr9_-_95640218 Show fit	1.80	ENST00000395506.3 ENST00000375495.3 ENST00000332591.6	ZNF484 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 484
chr12_+_106751436 Show fit	1.78	ENST00000228347.4	POLR3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	polymerase (RNA) III (DNA directed) polypeptide B
chr6_+_26402465 Show fit	1.75	ENST00000476549.2 ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1	BTN3A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin, subfamily 3, member A1
chr19_+_17858509 Show fit	1.74	ENST00000594202.1 ENST00000252771.7 ENST00000389133.4	FCHO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FCH domain only 1
chr17_+_41476327 Show fit	1.69	ENST00000320033.4	ARL4D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosylation factor-like 4D
chr3_+_108541608 Show fit	1.68	ENST00000426646.1	TRAT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	T cell receptor associated transmembrane adaptor 1
chr14_-_76127519 Show fit	1.68	ENST00000256319.6	C14orf1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 1
chr11_+_59856130 Show fit	1.66	ENST00000278888.3	MS4A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane-spanning 4-domains, subfamily A, member 2
chr17_-_40828969 Show fit	1.64	ENST00000591022.1 ENST00000587627.1 ENST00000293349.6	PLEKHH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_151735431 Show fit	1.58	ENST00000321531.5 ENST00000315067.8	OAZ3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ornithine decarboxylase antizyme 3
chr11_+_117947724 Show fit	1.58	ENST00000534111.1	TMPRSS4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protease, serine 4
chr12_-_22063787 Show fit	1.56	ENST00000544039.1	ABCC9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_+_220144052 Show fit	1.54	ENST00000425450.1 ENST00000392086.4 ENST00000421532.1	DNAJB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 2
chr14_+_32798462 Show fit	1.51	ENST00000280979.4	AKAP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	A kinase (PRKA) anchor protein 6
chr3_-_101039402 Show fit	1.47	ENST00000193391.7	IMPG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interphotoreceptor matrix proteoglycan 2
chr12_-_49418407 Show fit	1.45	ENST00000526209.1	KMT2D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific methyltransferase 2D
chr17_-_40337470 Show fit	1.42	ENST00000293330.1	HCRT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hypocretin (orexin) neuropeptide precursor
chr17_-_40829026 Show fit	1.41	ENST00000412503.1	PLEKHH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_+_15986364 Show fit	1.34	ENST00000345034.1	RSC1A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory solute carrier protein, family 1, member 1
chr17_-_77770830 Show fit	1.32	ENST00000269385.4	CBX8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromobox homolog 8
chr6_+_52051171 Show fit	1.32	ENST00000340057.1	IL17A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 17A
chr17_-_79623597 Show fit	1.31	ENST00000574024.1 ENST00000331056.5	PDE6G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 6G, cGMP-specific, rod, gamma
chr6_-_29395509 Show fit	1.27	ENST00000377147.2	OR11A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor, family 11, subfamily A, member 1
chr17_+_41323204 Show fit	1.26	ENST00000542611.1 ENST00000590996.1 ENST00000389312.4 ENST00000589872.1	NBR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neighbor of BRCA1 gene 1
chrX_+_113818545 Show fit	1.22	ENST00000371951.1 ENST00000276198.1 ENST00000371950.3	HTR2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr11_-_102668879 Show fit	1.19	ENST00000315274.6	MMP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 1 (interstitial collagenase)
chrX_+_37639302 Show fit	1.18	ENST00000545017.1 ENST00000536160.1	CYBB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b-245, beta polypeptide
chr1_-_152386732 Show fit	1.17	ENST00000271835.3	CRNN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cornulin
chr6_+_148663729 Show fit	1.15	ENST00000367467.3	SASH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAM and SH3 domain containing 1
chr11_+_77532155 Show fit	1.15	ENST00000532481.1 ENST00000526415.1 ENST00000393427.2 ENST00000527134.1 ENST00000304716.8	AAMDC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adipogenesis associated, Mth938 domain containing
chr20_-_50722183 Show fit	1.14	ENST00000371523.4	ZFP64 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ZFP64 zinc finger protein
chr5_+_142149932 Show fit	1.14	ENST00000274498.4	ARHGAP26 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 26
chr11_+_33061543 Show fit	1.11	ENST00000432887.1 ENST00000528898.1 ENST00000531632.2	TCP11L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 11, testis-specific-like 1
chr19_-_14606900 Show fit	1.10	ENST00000393029.3 ENST00000393028.1 ENST00000393033.4 ENST00000345425.2 ENST00000586027.1 ENST00000591349.1 ENST00000587210.1	GIPC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GIPC PDZ domain containing family, member 1
chr9_+_117904097 Show fit	1.08	ENST00000374016.1	DEC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	deleted in esophageal cancer 1
chr1_+_28261621 Show fit	0.99	ENST00000549094.1	SMPDL3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sphingomyelin phosphodiesterase, acid-like 3B
chr19_+_56459198 Show fit	0.98	ENST00000291971.3 ENST00000590542.1	NLRP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NLR family, pyrin domain containing 8
chr6_-_29396243 Show fit	0.94	ENST00000377148.1	OR11A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor, family 11, subfamily A, member 1
chr10_+_71561704 Show fit	0.94	ENST00000520267.1	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr9_+_130565147 Show fit	0.93	ENST00000373247.2 ENST00000373245.1 ENST00000393706.2 ENST00000373228.1	FPGS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	folylpolyglutamate synthase
chr7_+_142458507 Show fit	0.92	ENST00000492062.1	PRSS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protease, serine, 1 (trypsin 1)
chrY_+_14813160 Show fit	0.92	ENST00000338981.3	USP9Y Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 9, Y-linked
chr13_+_73632897 Show fit	0.90	ENST00000377687.4	KLF5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 5 (intestinal)
chr15_+_40697988 Show fit	0.86	ENST00000487418.2 ENST00000479013.2	IVD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	isovaleryl-CoA dehydrogenase
chr9_+_136501478 Show fit	0.86	ENST00000393056.2 ENST00000263611.2	DBH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr12_+_118573663 Show fit	0.84	ENST00000261313.2	PEBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatidylethanolamine binding protein 1
chr3_+_156009623 Show fit	0.82	ENST00000389634.5	KCNAB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr11_+_77532233 Show fit	0.81	ENST00000525409.1	AAMDC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adipogenesis associated, Mth938 domain containing

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	8.1	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
2.7	37.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
2.4	21.8	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
1.9	7.8	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
1.8	5.4	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.7	5.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
1.6	4.8	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
1.5	4.5	GO:0035602	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
1.5	11.8	GO:0001920	negative regulation of receptor recycling(GO:0001920)
1.4	9.8	GO:0071896	protein localization to adherens junction(GO:0071896)
1.4	4.2	GO:0071284	cellular response to lead ion(GO:0071284)
1.3	3.9	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.3	6.5	GO:0006041	glucosamine metabolic process(GO:0006041)
1.3	5.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
1.3	5.0	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
1.2	3.6	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.2	3.5	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.1	11.3	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
1.1	6.6	GO:0018095	protein polyglutamylation(GO:0018095)
1.1	3.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.0	5.2	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0	8.2	GO:1900113	histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.0	4.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
1.0	12.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.0	10.0	GO:0006685	sphingomyelin catabolic process(GO:0006685)
1.0	10.5	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.9	6.1	GO:0048241	epinephrine transport(GO:0048241)
0.9	11.3	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.8	3.4	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.8	7.5	GO:0016198	axon choice point recognition(GO:0016198)
0.7	16.9	GO:0007141	male meiosis I(GO:0007141)
0.7	2.0	GO:0060369	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.7	2.6	GO:0009822	alkaloid catabolic process(GO:0009822)
0.6	5.7	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6	4.8	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5	4.6	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.5	7.6	GO:0032836	glomerular basement membrane development(GO:0032836)
0.4	2.5	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.4	5.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.4	5.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.3	10.8	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.3	1.7	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.3	2.0	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3	2.3	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.3	1.6	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.3	0.9	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3	1.2	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3	1.5	GO:0001555	oocyte growth(GO:0001555)
0.3	1.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.3	4.7	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3	1.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.3	4.7	GO:0002347	response to tumor cell(GO:0002347)
0.3	7.6	GO:0071711	basement membrane organization(GO:0071711)
0.2	5.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.2	3.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2	1.2	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2	2.4	GO:0001865	NK T cell differentiation(GO:0001865)
0.2	1.4	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.2	6.8	GO:0051567	histone H3-K9 methylation(GO:0051567)
0.2	1.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.2	4.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.2	4.5	GO:0072643	interferon-gamma secretion(GO:0072643)
0.2	2.5	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	9.5	GO:0006458	'de novo' protein folding(GO:0006458)
0.2	0.9	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.2	2.1	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.2	6.8	GO:0070206	protein trimerization(GO:0070206)
0.2	4.6	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.2	16.5	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.2	11.2	GO:0030574	collagen catabolic process(GO:0030574)
0.1	2.7	GO:0007548	sex differentiation(GO:0007548)
0.1	4.1	GO:0007035	vacuolar acidification(GO:0007035)
0.1	3.7	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.7	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	0.8	GO:0060539	diaphragm development(GO:0060539)
0.1	3.0	GO:0044458	motile cilium assembly(GO:0044458)
0.1	0.8	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1	0.9	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.9	GO:0006552	leucine catabolic process(GO:0006552)
0.1	4.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	7.2	GO:0006611	protein export from nucleus(GO:0006611)
0.1	1.9	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	3.1	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.1	2.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	5.9	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	0.5	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	2.2	GO:0044744	protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.1	1.3	GO:0032967	positive regulation of collagen biosynthetic process(GO:0032967)
0.1	2.8	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1	0.8	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	2.9	GO:0006954	inflammatory response(GO:0006954)
0.0	2.2	GO:0016233	telomere capping(GO:0016233)
0.0	1.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	1.3	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	2.7	GO:0046847	filopodium assembly(GO:0046847)
0.0	1.3	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	3.9	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	2.6	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	1.6	GO:0010107	potassium ion import(GO:0010107)
0.0	3.5	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.0	2.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	1.8	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	1.9	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.2	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.2	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0060364	frontal suture morphogenesis(GO:0060364)
0.0	10.5	GO:0007517	muscle organ development(GO:0007517)
0.0	1.7	GO:0009306	protein secretion(GO:0009306)
0.0	2.6	GO:0046718	viral entry into host cell(GO:0046718)
0.0	2.9	GO:0030449	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0	0.5	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.5	GO:0014047	glutamate secretion(GO:0014047)
0.0	5.7	GO:0048511	rhythmic process(GO:0048511)
0.0	0.4	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	3.5	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.0	0.6	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.4	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.9	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	1.7	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	16.9	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
1.7	5.0	GO:0005588	collagen type V trimer(GO:0005588)
1.6	4.8	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
1.3	21.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.1	7.5	GO:0032584	growth cone membrane(GO:0032584)
1.0	3.9	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.9	2.8	GO:0097679	other organism cytoplasm(GO:0097679)
0.9	8.1	GO:0005638	lamin filament(GO:0005638)
0.9	5.4	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9	12.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.8	9.8	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.8	3.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.8	3.0	GO:0097224	sperm connecting piece(GO:0097224)
0.5	1.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.5	3.4	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4	2.0	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.4	4.7	GO:0060077	inhibitory synapse(GO:0060077)
0.4	2.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.3	2.5	GO:0035976	AP1 complex(GO:0035976)
0.3	8.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.3	4.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	5.1	GO:0000242	pericentriolar material(GO:0000242)
0.2	7.6	GO:0005605	basal lamina(GO:0005605)
0.2	2.9	GO:0036038	MKS complex(GO:0036038)
0.2	3.2	GO:0033270	voltage-gated sodium channel complex(GO:0001518) paranode region of axon(GO:0033270)
0.2	2.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.2	4.8	GO:0030673	axolemma(GO:0030673)
0.1	2.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	1.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	4.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.8	GO:1990635	proximal dendrite(GO:1990635)
0.1	1.3	GO:0035102	PRC1 complex(GO:0035102)
0.1	7.6	GO:0005604	basement membrane(GO:0005604)
0.1	6.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.9	GO:0042584	chromaffin granule membrane(GO:0042584)
0.1	1.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	10.5	GO:0043679	axon terminus(GO:0043679)
0.1	6.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	1.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	10.0	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.8	GO:0031209	SCAR complex(GO:0031209)
0.1	17.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	0.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	1.3	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	6.0	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	2.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	1.3	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	5.9	GO:0005802	trans-Golgi network(GO:0005802)
0.0	5.3	GO:0043197	dendritic spine(GO:0043197)
0.0	2.1	GO:0005814	centriole(GO:0005814)
0.0	36.9	GO:0005794	Golgi apparatus(GO:0005794)
0.0	5.1	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	3.0	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	3.1	GO:0030133	transport vesicle(GO:0030133)
0.0	2.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	5.2	GO:0030017	sarcomere(GO:0030017)
0.0	6.4	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	3.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	2.5	GO:0072562	blood microparticle(GO:0072562)
0.0	2.1	GO:0016324	apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.8	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
2.3	11.3	GO:0004771	sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.8	5.5	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
1.8	5.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.6	9.5	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
1.5	6.1	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.4	4.2	GO:0032767	copper-dependent protein binding(GO:0032767)
1.3	6.6	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
1.3	3.9	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.3	7.6	GO:0043237	laminin-1 binding(GO:0043237)
1.0	8.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
1.0	10.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.0	2.9	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.8	7.5	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.7	4.8	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.7	5.4	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5	11.3	GO:0035497	cAMP response element binding(GO:0035497)
0.5	3.2	GO:0030492	hemoglobin binding(GO:0030492)
0.5	2.3	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.5	4.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.4	8.0	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	5.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.3	8.9	GO:0005521	lamin binding(GO:0005521)
0.3	1.6	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.3	10.8	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.3	8.0	GO:0008266	poly(U) RNA binding(GO:0008266)
0.3	9.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	5.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	3.0	GO:0032027	myosin light chain binding(GO:0032027)
0.3	24.6	GO:0005518	collagen binding(GO:0005518)
0.2	3.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.2	3.4	GO:0043495	protein anchor(GO:0043495)
0.2	5.7	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2	3.5	GO:0015643	toxic substance binding(GO:0015643)
0.2	1.7	GO:0019863	IgE binding(GO:0019863)
0.2	4.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2	3.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2	19.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.2	5.0	GO:0001671	ATPase activator activity(GO:0001671)
0.2	2.6	GO:0070330	aromatase activity(GO:0070330)
0.2	5.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	4.1	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.9	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	3.6	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1	3.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	14.1	GO:0032947	protein complex scaffold(GO:0032947)
0.1	1.6	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.1	1.3	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	6.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	1.2	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	1.4	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1	2.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	4.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.1	38.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1	4.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	21.0	GO:0000287	magnesium ion binding(GO:0000287)
0.1	6.8	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	1.8	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	6.5	GO:0048029	monosaccharide binding(GO:0048029)
0.1	7.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.8	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	3.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.9	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	0.9	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.9	GO:0070410	co-SMAD binding(GO:0070410)
0.0	1.2	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	7.2	GO:0008201	heparin binding(GO:0008201)
0.0	33.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.8	GO:0070402	NADPH binding(GO:0070402)
0.0	1.4	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	1.3	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	1.3	GO:0030507	spectrin binding(GO:0030507)
0.0	8.3	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	1.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	6.3	GO:0030674	protein binding, bridging(GO:0030674)
0.0	2.6	GO:0001618	virus receptor activity(GO:0001618)
0.0	6.6	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	7.0	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	4.5	GO:0030246	carbohydrate binding(GO:0030246)
0.0	2.0	GO:0005178	integrin binding(GO:0005178)
0.0	3.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	2.2	GO:0042393	histone binding(GO:0042393)
0.0	1.1	GO:0017022	myosin binding(GO:0017022)
0.0	0.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.5	PID BARD1 PATHWAY	BARD1 signaling events
0.7	16.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5	10.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	11.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4	5.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.3	20.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	15.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.3	8.9	NABA COLLAGENS	Genes encoding collagen proteins
0.3	12.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	15.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.2	32.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	5.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	5.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	4.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	5.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	3.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	1.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	1.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	3.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	4.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	2.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.4	PID FGF PATHWAY	FGF signaling pathway
0.0	1.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	2.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.8	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.8	PID RHOA PATHWAY	RhoA signaling pathway
0.0	5.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	24.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.6	8.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.6	22.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.4	12.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	6.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4	5.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	9.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.3	4.5	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.3	10.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	10.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	6.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	5.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	3.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	4.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.2	3.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	5.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	2.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	2.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	8.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	3.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	4.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	2.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	4.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	4.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	3.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.0	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	2.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	2.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	10.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	1.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	2.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.6	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	2.4	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors