GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
MEF2C Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000081189.9	myocyte enhancer factor 2C

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MEF2C	hg19_v2_chr5_-_88119580_88119605	-0.06	4.0e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_111358372 Show fit	37.96	ENST00000548438.1 ENST00000228841.8	MYL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 2, regulatory, cardiac, slow
chr11_+_1860200 Show fit	31.70	ENST00000381911.1	TNNI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin I type 2 (skeletal, fast)
chr22_-_36013368 Show fit	26.11	ENST00000442617.1 ENST00000397326.2 ENST00000397328.1 ENST00000451685.1	MB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myoglobin
chr17_+_37821593 Show fit	23.59	ENST00000578283.1	TCAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	titin-cap
chr2_-_211168332 Show fit	22.62	ENST00000341685.4	MYL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 1, alkali; skeletal, fast
chr3_+_8543561 Show fit	22.55	ENST00000397386.3	LMCD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and cysteine-rich domains 1
chr11_-_19223523 Show fit	22.24	ENST00000265968.3	CSRP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr3_+_8543393 Show fit	21.64	ENST00000157600.3 ENST00000415597.1 ENST00000535732.1	LMCD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and cysteine-rich domains 1
chr11_+_1860832 Show fit	21.57	ENST00000252898.7	TNNI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin I type 2 (skeletal, fast)
chr3_-_52486841 Show fit	21.41	ENST00000496590.1	TNNC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin C type 1 (slow)
chr17_+_4855053 Show fit	20.69	ENST00000518175.1	ENO3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enolase 3 (beta, muscle)
chr11_+_1860682 Show fit	20.30	ENST00000381906.1	TNNI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin I type 2 (skeletal, fast)
chr11_+_1942580 Show fit	19.93	ENST00000381558.1	TNNT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T type 3 (skeletal, fast)
chr7_+_75931861 Show fit	19.59	ENST00000248553.6	HSPB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 27kDa protein 1
chrX_+_135278908 Show fit	17.83	ENST00000539015.1 ENST00000370683.1	FHL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 1
chr3_+_8543533 Show fit	17.65	ENST00000454244.1	LMCD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and cysteine-rich domains 1
chrX_+_135279179 Show fit	17.50	ENST00000370676.3	FHL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 1
chr1_-_201391149 Show fit	16.75	ENST00000555948.1 ENST00000556362.1	TNNI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin I type 1 (skeletal, slow)
chr16_-_31439735 Show fit	14.15	ENST00000287490.4	COX6A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome c oxidase subunit VIa polypeptide 2
chr3_-_46904918 Show fit	13.40	ENST00000395869.1	MYL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904946 Show fit	13.35	ENST00000292327.4	MYL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_-_154164534 Show fit	12.95	ENST00000271850.7 ENST00000368530.2	TPM3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomyosin 3
chr7_-_44105158 Show fit	12.81	ENST00000297283.3	PGAM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglycerate mutase 2 (muscle)
chr11_+_1940925 Show fit	12.40	ENST00000453458.1 ENST00000381557.2 ENST00000381589.3 ENST00000381579.3 ENST00000381563.4 ENST00000344578.4	TNNT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T type 3 (skeletal, fast)
chr11_+_1940786 Show fit	11.79	ENST00000278317.6 ENST00000381561.4 ENST00000381548.3 ENST00000360603.3 ENST00000381549.3	TNNT3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T type 3 (skeletal, fast)
chr4_-_186697044 Show fit	11.69	ENST00000437304.2	SORBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbin and SH3 domain containing 2
chr2_+_170366203 Show fit	11.15	ENST00000284669.1	KLHL41 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch-like family member 41
chr1_-_201390846 Show fit	11.12	ENST00000367312.1 ENST00000555340.2 ENST00000361379.4	TNNI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin I type 1 (skeletal, slow)
chr4_+_169418195 Show fit	10.49	ENST00000261509.6 ENST00000335742.7	PALLD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	palladin, cytoskeletal associated protein
chr10_+_88428206 Show fit	10.19	ENST00000429277.2 ENST00000458213.2 ENST00000352360.5	LDB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 3
chr14_-_23877474 Show fit	9.90	ENST00000405093.3	MYH6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, heavy chain 6, cardiac muscle, alpha
chr8_+_1993152 Show fit	8.72	ENST00000262113.4	MYOM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myomesin 2
chr1_+_160160283 Show fit	8.72	ENST00000368079.3	CASQ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160346 Show fit	8.61	ENST00000368078.3	CASQ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calsequestrin 1 (fast-twitch, skeletal muscle)
chr18_-_3220106 Show fit	8.55	ENST00000356443.4 ENST00000400569.3	MYOM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myomesin 1
chr20_+_43211149 Show fit	8.12	ENST00000372886.1	PKIG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr8_+_1993173 Show fit	8.07	ENST00000523438.1	MYOM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myomesin 2
chr10_+_88428370 Show fit	7.98	ENST00000372066.3 ENST00000263066.6 ENST00000372056.4 ENST00000310944.6 ENST00000361373.4 ENST00000542786.1	LDB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain binding 3
chr8_-_33457453 Show fit	7.86	ENST00000523956.1 ENST00000256261.4	DUSP26 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 26 (putative)
chr1_-_116311402 Show fit	7.36	ENST00000261448.5	CASQ2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calsequestrin 2 (cardiac muscle)
chr16_+_30075595 Show fit	7.22	ENST00000563060.2	ALDOA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aldolase A, fructose-bisphosphate
chr16_+_30075463 Show fit	7.17	ENST00000562168.1 ENST00000569545.1	ALDOA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aldolase A, fructose-bisphosphate
chr16_+_30075783 Show fit	7.12	ENST00000412304.2	ALDOA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aldolase A, fructose-bisphosphate
chr3_+_193853927 Show fit	7.11	ENST00000232424.3	HES1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hes family bHLH transcription factor 1
chr10_-_75415825 Show fit	7.03	ENST00000394810.2	SYNPO2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptopodin 2-like
chr1_-_31845914 Show fit	6.83	ENST00000373713.2	FABP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr19_+_35629702 Show fit	6.53	ENST00000351325.4	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr4_-_88450612 Show fit	6.43	ENST00000418378.1 ENST00000282470.6	SPARCL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SPARC-like 1 (hevin)
chr19_+_35630022 Show fit	6.40	ENST00000589209.1	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr4_-_186696425 Show fit	6.10	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sorbin and SH3 domain containing 2
chr4_+_120056939 Show fit	5.99	ENST00000307128.5	MYOZ2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myozenin 2
chr1_+_156095951 Show fit	5.85	ENST00000448611.2 ENST00000368297.1	LMNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lamin A/C
chr4_-_57547454 Show fit	5.58	ENST00000556376.2	HOPX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HOP homeobox
chr4_-_57547870 Show fit	5.53	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HOP homeobox
chr10_-_45474237 Show fit	5.52	ENST00000448778.1 ENST00000298295.3	C10orf10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 10 open reading frame 10
chr19_+_6739662 Show fit	5.50	ENST00000313285.8 ENST00000313244.9 ENST00000596758.1	TRIP10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroid hormone receptor interactor 10
chr4_+_55095264 Show fit	5.46	ENST00000257290.5	PDGFRA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet-derived growth factor receptor, alpha polypeptide
chr3_+_179370517 Show fit	5.38	ENST00000263966.3	USP13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr10_-_75410771 Show fit	5.31	ENST00000372873.4	SYNPO2L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptopodin 2-like
chr3_+_127634312 Show fit	5.30	ENST00000407609.3	KBTBD12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch repeat and BTB (POZ) domain containing 12
chr3_+_127634069 Show fit	5.18	ENST00000405109.1	KBTBD12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	kelch repeat and BTB (POZ) domain containing 12
chr5_+_53751445 Show fit	5.11	ENST00000302005.1	HSPB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock 27kDa protein 3
chr19_+_35630344 Show fit	5.05	ENST00000455515.2	FXYD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	FXYD domain containing ion transport regulator 1
chr5_+_140749803 Show fit	4.90	ENST00000576222.1	PCDHGB3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin gamma subfamily B, 3
chr4_+_41362796 Show fit	4.75	ENST00000508501.1 ENST00000512946.1 ENST00000313860.7 ENST00000512632.1 ENST00000512820.1	LIMCH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and calponin homology domains 1
chr1_-_115238207 Show fit	4.68	ENST00000520113.2 ENST00000369538.3 ENST00000353928.6	AMPD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenosine monophosphate deaminase 1
chr13_+_76334567 Show fit	4.48	ENST00000321797.8	LMO7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain 7
chr18_-_3219847 Show fit	4.24	ENST00000261606.7	MYOM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myomesin 1
chr16_+_84328252 Show fit	4.21	ENST00000219454.5	WFDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WAP four-disulfide core domain 1
chr4_+_169418255 Show fit	4.15	ENST00000505667.1 ENST00000511948.1	PALLD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	palladin, cytoskeletal associated protein
chr16_+_84328429 Show fit	4.12	ENST00000568638.1	WFDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WAP four-disulfide core domain 1
chr13_+_76334795 Show fit	3.86	ENST00000526202.1 ENST00000465261.2	LMO7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM domain 7
chr1_+_156096336 Show fit	3.83	ENST00000504687.1 ENST00000473598.2	LMNA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lamin A/C
chr10_-_115423792 Show fit	3.69	ENST00000369360.3 ENST00000360478.3 ENST00000359988.3 ENST00000369358.4	NRAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nebulin-related anchoring protein
chr21_+_27011584 Show fit	3.67	ENST00000400532.1 ENST00000480456.1 ENST00000312957.5	JAM2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	junctional adhesion molecule 2
chr7_-_56160625 Show fit	3.59	ENST00000446428.1 ENST00000432123.1 ENST00000452681.2 ENST00000537360.1	PHKG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphorylase kinase, gamma 1 (muscle)
chr16_+_6069072 Show fit	3.46	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_+_48807351 Show fit	3.45	ENST00000303004.3	CEBPB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_23652849 Show fit	3.28	ENST00000316902.7 ENST00000469263.1 ENST00000525062.1 ENST00000524758.1	SLC7A8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr20_+_44035847 Show fit	3.19	ENST00000372712.2	DBNDD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_74003818 Show fit	3.06	ENST00000311148.4	ACOT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	acyl-CoA thioesterase 1
chr1_-_12677714 Show fit	3.04	ENST00000376223.2	DHRS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dehydrogenase/reductase (SDR family) member 3
chr7_-_56160666 Show fit	3.03	ENST00000297373.2	PHKG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphorylase kinase, gamma 1 (muscle)
chr6_-_169654139 Show fit	3.03	ENST00000366787.3	THBS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thrombospondin 2
chr11_-_47374246 Show fit	2.89	ENST00000545968.1 ENST00000399249.2 ENST00000256993.4	MYBPC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin binding protein C, cardiac
chr3_+_138067521 Show fit	2.87	ENST00000494949.1	MRAS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscle RAS oncogene homolog
chr3_+_159570722 Show fit	2.83	ENST00000482804.1	SCHIP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	schwannomin interacting protein 1
chr11_+_19799327 Show fit	2.76	ENST00000540292.1	NAV2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuron navigator 2
chr3_-_192445289 Show fit	2.70	ENST00000430714.1 ENST00000418610.1 ENST00000448795.1 ENST00000445105.2	FGF12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibroblast growth factor 12
chrX_+_153046456 Show fit	2.69	ENST00000393786.3 ENST00000370104.1 ENST00000370108.3 ENST00000370101.3 ENST00000430541.1 ENST00000370100.1	SRPK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SRSF protein kinase 3
chr4_+_41614909 Show fit	2.61	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and calponin homology domains 1
chr9_+_100263912 Show fit	2.55	ENST00000259365.4	TMOD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tropomodulin 1
chr2_-_151344172 Show fit	2.55	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho family GTPase 3
chr6_-_45983581 Show fit	2.55	ENST00000339561.6	CLIC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride intracellular channel 5
chr11_+_3666335 Show fit	2.54	ENST00000250693.1	ART1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosyltransferase 1
chr15_+_42651691 Show fit	2.45	ENST00000357568.3 ENST00000349748.3 ENST00000318023.7 ENST00000397163.3	CAPN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calpain 3, (p94)
chr10_-_29923893 Show fit	2.43	ENST00000355867.4	SVIL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	supervillin
chr2_-_190044480 Show fit	2.40	ENST00000374866.3	COL5A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type V, alpha 2
chr9_-_21995249 Show fit	2.33	ENST00000494262.1	CDKN2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase inhibitor 2A
chr8_-_49834299 Show fit	2.31	ENST00000396822.1	SNAI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	snail family zinc finger 2
chr8_-_49833978 Show fit	2.26	ENST00000020945.1	SNAI2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	snail family zinc finger 2
chr16_+_7382745 Show fit	2.23	ENST00000436368.2 ENST00000311745.5 ENST00000355637.4 ENST00000340209.4	RBFOX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_+_63661053 Show fit	2.15	ENST00000279873.7	ARID5B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 5B (MRF1-like)
chr18_+_9708162 Show fit	2.11	ENST00000578921.1	RAB31 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB31, member RAS oncogene family
chr4_+_95373037 Show fit	2.10	ENST00000359265.4 ENST00000437932.1 ENST00000380180.3 ENST00000318007.5 ENST00000450793.1 ENST00000538141.1 ENST00000317968.4 ENST00000512274.1 ENST00000503974.1 ENST00000504489.1 ENST00000542407.1	PDLIM5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	PDZ and LIM domain 5
chr7_-_150946015 Show fit	2.09	ENST00000262188.8	SMARCD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr17_-_10372875 Show fit	2.05	ENST00000255381.2	MYH4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, heavy chain 4, skeletal muscle
chr14_-_61748550 Show fit	2.05	ENST00000555868.1	TMEM30B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 30B
chr15_+_67418047 Show fit	1.86	ENST00000540846.2	SMAD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 3
chr3_+_4535155 Show fit	1.86	ENST00000544951.1	ITPR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_30569506 Show fit	1.67	ENST00000421976.2	AC109642.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AC109642.1
chr17_-_79604075 Show fit	1.66	ENST00000374747.5 ENST00000539314.1 ENST00000331134.6	NPLOC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear protein localization 4 homolog (S. cerevisiae)
chr21_+_39628655 Show fit	1.60	ENST00000398925.1 ENST00000398928.1 ENST00000328656.4 ENST00000443341.1	KCNJ15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_39125365 Show fit	1.60	ENST00000559001.1 ENST00000464276.2	POU6F2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POU class 6 homeobox 2
chr3_+_138067314 Show fit	1.59	ENST00000423968.2	MRAS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscle RAS oncogene homolog
chr9_-_110251836 Show fit	1.58	ENST00000374672.4	KLF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 4 (gut)
chr17_-_1389228 Show fit	1.55	ENST00000438665.2	MYO1C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin IC
chr14_-_21493123 Show fit	1.53	ENST00000556147.1 ENST00000554489.1 ENST00000555657.1 ENST00000557274.1 ENST00000555158.1 ENST00000554833.1 ENST00000555384.1 ENST00000556420.1 ENST00000554893.1 ENST00000553503.1 ENST00000555733.1 ENST00000553867.1 ENST00000397856.3 ENST00000397855.3 ENST00000556008.1 ENST00000557182.1 ENST00000554483.1 ENST00000556688.1 ENST00000397853.3 ENST00000556329.2 ENST00000554143.1 ENST00000397851.2 ENST00000555142.1 ENST00000557676.1 ENST00000556924.1	NDRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NDRG family member 2
chr7_+_120629653 Show fit	1.51	ENST00000450913.2 ENST00000340646.5	CPED1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin-like and PC-esterase domain containing 1
chr3_+_69928256 Show fit	1.50	ENST00000394355.2	MITF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microphthalmia-associated transcription factor
chr21_-_42219065 Show fit	1.47	ENST00000400454.1	DSCAM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Down syndrome cell adhesion molecule
chr7_+_30951461 Show fit	1.47	ENST00000311813.4	AQP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aquaporin 1 (Colton blood group)
chr7_-_151217001 Show fit	1.47	ENST00000262187.5	RHEB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras homolog enriched in brain
chr9_-_33402506 Show fit	1.46	ENST00000377425.4 ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1	AQP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aquaporin 7
chr3_+_138067666 Show fit	1.46	ENST00000475711.1 ENST00000464896.1	MRAS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscle RAS oncogene homolog
chr10_+_71561630 Show fit	1.44	ENST00000398974.3 ENST00000398971.3 ENST00000398968.3 ENST00000398966.3 ENST00000398964.3 ENST00000398969.3 ENST00000356340.3 ENST00000398972.3 ENST00000398973.3	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr21_+_39628852 Show fit	1.40	ENST00000398938.2	KCNJ15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_230513367 Show fit	1.39	ENST00000321327.2 ENST00000525115.1	PGBD5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	piggyBac transposable element derived 5
chr10_+_71561704 Show fit	1.37	ENST00000520267.1	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr17_-_10276319 Show fit	1.34	ENST00000252172.4 ENST00000418404.3	MYH13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, heavy chain 13, skeletal muscle
chr2_+_145780767 Show fit	1.31	ENST00000599358.1 ENST00000596278.1 ENST00000596747.1 ENST00000608652.1 ENST00000609705.1 ENST00000608432.1 ENST00000596970.1 ENST00000602041.1 ENST00000601578.1 ENST00000596034.1 ENST00000414195.2 ENST00000594837.1	TEX41 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	testis expressed 41 (non-protein coding)
chr1_-_230850043 Show fit	1.30	ENST00000366667.4	AGT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_201979645 Show fit	1.29	ENST00000367284.5 ENST00000367283.3	ELF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_+_135741576 Show fit	1.25	ENST00000334546.2	PPP2R3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2, regulatory subunit B'', alpha
chr17_-_1389419 Show fit	1.22	ENST00000575158.1	MYO1C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin IC
chr19_-_893200 Show fit	1.21	ENST00000269814.4 ENST00000395808.3 ENST00000312090.6 ENST00000325464.1	MED16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 16
chr17_+_65040678 Show fit	1.19	ENST00000226021.3	CACNG1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, gamma subunit 1
chr3_+_36421826 Show fit	1.18	ENST00000273183.3	STAC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 and cysteine rich domain
chr9_+_5231413 Show fit	1.13	ENST00000239316.4	INSL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like 4 (placenta)
chr17_-_42200958 Show fit	1.11	ENST00000336057.5	HDAC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 5
chr1_-_201346761 Show fit	1.10	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T type 2 (cardiac)
chr18_+_29027696 Show fit	1.01	ENST00000257189.4	DSG3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	desmoglein 3
chrX_-_30327495 Show fit	0.95	ENST00000453287.1	NR0B1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 0, group B, member 1
chr18_+_3252206 Show fit	0.94	ENST00000578562.2	MYL12A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_18034701 Show fit	0.94	ENST00000265965.5	SERGEF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	secretion regulating guanine nucleotide exchange factor
chr10_+_71561649 Show fit	0.86	ENST00000398978.3 ENST00000354547.3 ENST00000357811.3	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr10_+_32856764 Show fit	0.85	ENST00000375030.2 ENST00000375028.3	C10orf68 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_+_170633047 Show fit	0.84	ENST00000239461.6 ENST00000497230.2	PRRX1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	paired related homeobox 1
chr1_-_59249732 Show fit	0.84	ENST00000371222.2	JUN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	jun proto-oncogene
chr2_+_173686303 Show fit	0.80	ENST00000397087.3	RAPGEF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr17_-_42200996 Show fit	0.80	ENST00000587135.1 ENST00000225983.6 ENST00000393622.2 ENST00000588703.1	HDAC5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 5
chr2_-_148778323 Show fit	0.78	ENST00000440042.1 ENST00000535373.1 ENST00000540442.1 ENST00000536575.1	ORC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	origin recognition complex, subunit 4
chr2_+_233497931 Show fit	0.76	ENST00000264059.3	EFHD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EF-hand domain family, member D1
chr22_-_51016846 Show fit	0.73	ENST00000312108.7 ENST00000395650.2	CPT1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carnitine palmitoyltransferase 1B (muscle)
chr2_+_166152283 Show fit	0.71	ENST00000375427.2	SCN2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, voltage-gated, type II, alpha subunit
chr1_+_145524891 Show fit	0.69	ENST00000369304.3	ITGA10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 10
chr7_-_82073109 Show fit	0.65	ENST00000356860.3	CACNA2D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_38071122 Show fit	0.64	ENST00000334661.4	PLCD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase C, delta 1
chr1_+_92632542 Show fit	0.62	ENST00000409154.4 ENST00000370378.4	KIAA1107 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA1107
chr1_-_173174681 Show fit	0.62	ENST00000367718.1	TNFSF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor necrosis factor (ligand) superfamily, member 4
chr8_-_62602327 Show fit	0.58	ENST00000445642.3 ENST00000517847.2 ENST00000389204.4 ENST00000517661.1 ENST00000517903.1 ENST00000522603.1 ENST00000522349.1 ENST00000522835.1 ENST00000541428.1 ENST00000518306.1	ASPH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aspartate beta-hydroxylase
chr2_+_220143989 Show fit	0.58	ENST00000336576.5	DNAJB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 2
chr8_-_17533838 Show fit	0.55	ENST00000400046.1	MTUS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated tumor suppressor 1
chr1_-_157014865 Show fit	0.54	ENST00000361409.2	ARHGEF11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho guanine nucleotide exchange factor (GEF) 11
chr11_+_69924639 Show fit	0.54	ENST00000538023.1 ENST00000398543.2	ANO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	anoctamin 1, calcium activated chloride channel
chr19_-_1021113 Show fit	0.53	ENST00000333175.5 ENST00000356663.3	TMEM259 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 259
chr10_+_71562180 Show fit	0.46	ENST00000517713.1 ENST00000522165.1 ENST00000520133.1	COL13A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type XIII, alpha 1
chr1_-_713985 Show fit	0.46	ENST00000428504.1	RP11-206L10.2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-206L10.2
chr10_-_61900762 Show fit	0.45	ENST00000355288.2	ANK3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_62704005 Show fit	0.43	ENST00000337910.5	RHOBTB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho-related BTB domain containing 1
chr7_-_82073031 Show fit	0.43	ENST00000356253.5 ENST00000423588.1	CACNA2D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_+_154002189 Show fit	0.42	ENST00000332007.3	DPP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dipeptidyl-peptidase 6
chr7_+_142457315 Show fit	0.41	ENST00000486171.1 ENST00000311737.7	PRSS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protease, serine, 1 (trypsin 1)
chr11_+_12766583 Show fit	0.40	ENST00000361985.2	TEAD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_151217166 Show fit	0.38	ENST00000496004.1	RHEB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras homolog enriched in brain
chr22_-_51017084 Show fit	0.35	ENST00000360719.2 ENST00000457250.1 ENST00000440709.1	CPT1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carnitine palmitoyltransferase 1B (muscle)
chr3_-_11610255 Show fit	0.32	ENST00000424529.2	VGLL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vestigial like 4 (Drosophila)
chr5_-_115910630 Show fit	0.30	ENST00000343348.6	SEMA6A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_46924829 Show fit	0.29	ENST00000313049.5	PTH1R Links Ensembl NCBI GeneCards UniProt NextProt Show fit	parathyroid hormone 1 receptor
chr10_+_124134201 Show fit	0.26	ENST00000368990.3 ENST00000368988.1 ENST00000368989.2 ENST00000463663.2	PLEKHA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_208030647 Show fit	0.24	ENST00000309446.6	KLF7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 7 (ubiquitous)
chrX_+_9217932 Show fit	0.24	ENST00000432442.1	GS1-519E5.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GS1-519E5.1
chr2_+_109204743 Show fit	0.23	ENST00000332345.6	LIMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and senescent cell antigen-like domains 1
chr13_+_97928395 Show fit	0.21	ENST00000445661.2	MBNL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	muscleblind-like splicing regulator 2
chr3_-_3151664 Show fit	0.21	ENST00000256452.3 ENST00000311981.8 ENST00000430514.2 ENST00000456302.1	IL5RA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 5 receptor, alpha
chr3_+_113616317 Show fit	0.19	ENST00000440446.2 ENST00000488680.1	GRAMD1C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 1C
chr7_+_5919458 Show fit	0.17	ENST00000416608.1	OCM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	oncomodulin
chr2_+_145780739 Show fit	0.16	ENST00000597173.1 ENST00000602108.1 ENST00000420472.1	TEX41 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	testis expressed 41 (non-protein coding)
chr10_+_121652204 Show fit	0.16	ENST00000369075.3 ENST00000543134.1	SEC23IP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SEC23 interacting protein
chr14_+_78870030 Show fit	0.14	ENST00000553631.1 ENST00000554719.1	NRXN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 3
chr1_+_221051699 Show fit	0.14	ENST00000366903.6	HLX Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H2.0-like homeobox
chr17_-_72855989 Show fit	0.13	ENST00000293190.5	GRIN2C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr4_+_110834033 Show fit	0.11	ENST00000509793.1 ENST00000265171.5	EGF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epidermal growth factor
chr1_-_40042416 Show fit	0.11	ENST00000372857.3 ENST00000372856.3 ENST00000531243.2 ENST00000451091.2	PABPC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	poly(A) binding protein, cytoplasmic 4 (inducible form)
chr22_+_45680822 Show fit	0.09	ENST00000216211.4 ENST00000396082.2	UPK3A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	uroplakin 3A
chr3_+_4535025 Show fit	0.07	ENST00000302640.8 ENST00000354582.6 ENST00000423119.2 ENST00000357086.4 ENST00000456211.2	ITPR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol 1,4,5-trisphosphate receptor, type 1
chr3_-_101039402 Show fit	0.07	ENST00000193391.7	IMPG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interphotoreceptor matrix proteoglycan 2
chr3_+_154797877 Show fit	0.05	ENST00000462745.1 ENST00000493237.1	MME Links Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane metallo-endopeptidase
chr9_+_130565147 Show fit	0.04	ENST00000373247.2 ENST00000373245.1 ENST00000393706.2 ENST00000373228.1	FPGS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	folylpolyglutamate synthase
chr1_+_41174988 Show fit	0.04	ENST00000372652.1	NFYC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear transcription factor Y, gamma

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.5	45.8	GO:0035995	detection of muscle stretch(GO:0035995)
5.6	22.5	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
4.9	19.6	GO:0099640	axo-dendritic protein transport(GO:0099640)
4.7	38.0	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
3.7	29.6	GO:0002074	extraocular skeletal muscle development(GO:0002074)
3.5	17.3	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
3.3	26.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
3.2	12.8	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
3.0	18.0	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.9	225.3	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
2.6	7.9	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.5	61.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
2.4	7.1	GO:0021558	midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
2.3	6.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.9	9.7	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
1.8	5.5	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.5	4.6	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.4	7.0	GO:0071313	cellular response to caffeine(GO:0071313)
1.3	5.4	GO:0035523	protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.2	21.5	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8	21.2	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.8	1.6	GO:0048867	stem cell fate determination(GO:0048867)
0.8	11.2	GO:2000291	regulation of pseudopodium assembly(GO:0031272) regulation of myoblast proliferation(GO:2000291)
0.7	14.6	GO:0003334	keratinocyte development(GO:0003334)
0.7	2.8	GO:0021564	vagus nerve development(GO:0021564)
0.7	14.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6	20.7	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6	2.4	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.6	32.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.6	20.6	GO:0045214	sarcomere organization(GO:0045214)
0.5	11.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.5	1.6	GO:0071409	negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.5	2.1	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.5	8.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5	1.5	GO:0072019	nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.5	1.9	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.5	4.7	GO:0032264	IMP salvage(GO:0032264)
0.5	2.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	1.9	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.3	2.3	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.3	0.6	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3	2.7	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.3	1.5	GO:0015793	glycerol transport(GO:0015793)
0.3	3.5	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3	2.6	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.2	1.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.2	3.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	0.8	GO:0035026	leading edge cell differentiation(GO:0035026)
0.2	0.6	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2	6.6	GO:0005980	glycogen catabolic process(GO:0005980)
0.2	2.0	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2	0.9	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.2	1.1	GO:0098903	membrane depolarization during bundle of His cell action potential(GO:0086048) regulation of membrane repolarization during action potential(GO:0098903)
0.2	11.5	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.2	1.7	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	1.9	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1	1.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.8	GO:0048664	neuron fate determination(GO:0048664)
0.1	1.3	GO:0060056	mammary gland involution(GO:0060056)
0.1	1.5	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1	0.4	GO:0071286	positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	3.3	GO:0015695	organic cation transport(GO:0015695)
0.1	5.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	1.5	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	2.3	GO:0030239	myofibril assembly(GO:0030239)
0.1	2.9	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.1	7.2	GO:0061045	negative regulation of wound healing(GO:0061045)
0.1	0.3	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
0.1	0.2	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	0.5	GO:0015705	iodide transport(GO:0015705)
0.1	2.5	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	0.7	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1	2.1	GO:0016577	histone demethylation(GO:0016577)
0.1	2.1	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.1	1.1	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1	5.6	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.5	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	5.9	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	2.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	3.2	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	1.2	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	2.7	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	1.5	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	1.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.6	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	1.0	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	7.8	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	1.2	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.7	GO:0010107	potassium ion import(GO:0010107)
0.0	3.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	1.2	GO:0061053	somite development(GO:0061053)
0.0	0.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	2.8	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.0	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0	0.4	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.0	168.1	GO:0005861	troponin complex(GO:0005861)
3.9	15.7	GO:0005863	striated muscle myosin thick filament(GO:0005863)
3.5	38.0	GO:0097512	cardiac myofibril(GO:0097512)
3.4	20.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
2.4	79.5	GO:0005859	muscle myosin complex(GO:0005859)
2.2	24.7	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
1.1	9.7	GO:0005638	lamin filament(GO:0005638)
1.0	29.3	GO:0031143	pseudopodium(GO:0031143)
1.0	4.1	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.0	14.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.9	18.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8	2.4	GO:0005588	collagen type V trimer(GO:0005588)
0.7	6.6	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.7	137.1	GO:0031674	I band(GO:0031674)
0.7	2.8	GO:0045160	myosin I complex(GO:0045160)
0.7	12.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.6	1.9	GO:0005955	calcineurin complex(GO:0005955)
0.6	3.7	GO:0005927	muscle tendon junction(GO:0005927)
0.5	1.5	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.4	2.6	GO:0005865	striated muscle thin filament(GO:0005865)
0.3	2.4	GO:0036449	microtubule minus-end(GO:0036449)
0.3	5.5	GO:0001891	phagocytic cup(GO:0001891)
0.3	2.8	GO:0005614	interstitial matrix(GO:0005614)
0.2	2.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.2	1.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.2	0.7	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.2	1.2	GO:0030315	T-tubule(GO:0030315)
0.2	3.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	11.0	GO:0016528	sarcoplasm(GO:0016528)
0.2	10.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	1.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	1.0	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.8	GO:0035976	AP1 complex(GO:0035976)
0.1	61.8	GO:0031012	extracellular matrix(GO:0031012)
0.1	2.1	GO:0071564	npBAF complex(GO:0071564)
0.1	0.4	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	0.7	GO:0033268	node of Ranvier(GO:0033268)
0.1	5.5	GO:0005902	microvillus(GO:0005902)
0.1	27.5	GO:0005925	focal adhesion(GO:0005925)
0.0	1.0	GO:0030057	desmosome(GO:0030057)
0.0	3.2	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	7.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.2	GO:0016592	mediator complex(GO:0016592)
0.0	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	2.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	2.2	GO:0034707	chloride channel complex(GO:0034707)
0.0	1.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	3.5	GO:0000779	condensed chromosome, centromeric region(GO:0000779)
0.0	3.7	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.9	GO:0016235	aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.0	44.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
6.8	95.0	GO:0031014	troponin T binding(GO:0031014)
6.7	26.8	GO:0032038	myosin II heavy chain binding(GO:0032038)
6.5	19.6	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
5.9	29.6	GO:0051373	FATZ binding(GO:0051373)
3.8	45.5	GO:0032036	myosin heavy chain binding(GO:0032036)
3.4	20.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
3.2	12.8	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
3.2	22.2	GO:0031433	telethonin binding(GO:0031433)
3.1	66.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
2.3	6.8	GO:0070538	oleic acid binding(GO:0070538)
2.0	26.1	GO:0005344	oxygen transporter activity(GO:0005344)
2.0	21.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
1.8	5.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.8	5.4	GO:1904288	BAT3 complex binding(GO:1904288)
1.7	9.9	GO:0017018	myosin phosphatase activity(GO:0017018)
1.6	7.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.7	6.6	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.7	17.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.6	1.1	GO:0030172	troponin C binding(GO:0030172)
0.5	38.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.5	2.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5	1.5	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.5	14.1	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5	1.9	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5	1.9	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.4	3.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.4	8.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4	1.2	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4	1.9	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.4	1.5	GO:0015254	glycerol channel activity(GO:0015254)
0.3	1.6	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3	3.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.3	3.3	GO:0019534	toxin transporter activity(GO:0019534)
0.2	1.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.2	20.2	GO:0005254	chloride channel activity(GO:0005254)
0.2	6.2	GO:0000146	microfilament motor activity(GO:0000146)
0.2	57.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.2	2.6	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.7	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.9	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	2.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	46.2	GO:0003779	actin binding(GO:0003779)
0.1	1.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	6.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	9.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	15.8	GO:0044325	ion channel binding(GO:0044325)
0.1	1.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	7.4	GO:0051087	chaperone binding(GO:0051087)
0.1	4.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	1.7	GO:0071837	HMG box domain binding(GO:0071837)
0.1	2.1	GO:0032452	histone demethylase activity(GO:0032452)
0.1	0.2	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	0.3	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	26.1	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.1	9.6	GO:0008201	heparin binding(GO:0008201)
0.1	1.7	GO:0043130	ubiquitin binding(GO:0043130)
0.1	1.7	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	4.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	1.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.7	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0017130	poly(C) RNA binding(GO:0017130)
0.0	0.8	GO:0030552	cAMP binding(GO:0030552)
0.0	2.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.4	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	1.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	12.2	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	4.0	GO:0005096	GTPase activator activity(GO:0005096)
0.0	3.0	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	38.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.3	19.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	23.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	7.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	3.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	5.5	PID INSULIN PATHWAY	Insulin Pathway
0.1	2.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	4.6	NABA COLLAGENS	Genes encoding collagen proteins
0.1	7.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	9.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	4.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	3.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	1.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.8	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.9	ST GAQ PATHWAY	G alpha q Pathway
0.0	2.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	2.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	260.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
1.1	55.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	6.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	2.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	19.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	4.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.5	REACTOME DEFENSINS	Genes involved in Defensins
0.1	5.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	1.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	10.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	1.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	4.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	0.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	5.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	2.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor