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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MEF2C

Z-value: 0.17

Motif logo

Transcription factors associated with MEF2C

Gene Symbol Gene ID Gene Info
ENSG00000081189.9 myocyte enhancer factor 2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Chg19_v2_chr5_-_88119580_88119605-0.064.0e-01Click!

Activity profile of MEF2C motif

Sorted Z-values of MEF2C motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_111358372 37.96 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr11_+_1860200 31.70 ENST00000381911.1
troponin I type 2 (skeletal, fast)
chr22_-_36013368 26.11 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr17_+_37821593 23.59 ENST00000578283.1
titin-cap
chr2_-_211168332 22.62 ENST00000341685.4
myosin, light chain 1, alkali; skeletal, fast
chr3_+_8543561 22.55 ENST00000397386.3
LIM and cysteine-rich domains 1
chr11_-_19223523 22.24 ENST00000265968.3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr3_+_8543393 21.64 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr11_+_1860832 21.57 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr3_-_52486841 21.41 ENST00000496590.1
troponin C type 1 (slow)
chr17_+_4855053 20.69 ENST00000518175.1
enolase 3 (beta, muscle)
chr11_+_1860682 20.30 ENST00000381906.1
troponin I type 2 (skeletal, fast)
chr11_+_1942580 19.93 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr7_+_75931861 19.59 ENST00000248553.6
heat shock 27kDa protein 1
chrX_+_135278908 17.83 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr3_+_8543533 17.65 ENST00000454244.1
LIM and cysteine-rich domains 1
chrX_+_135279179 17.50 ENST00000370676.3
four and a half LIM domains 1
chr1_-_201391149 16.75 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr16_-_31439735 14.15 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr3_-_46904918 13.40 ENST00000395869.1
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904946 13.35 ENST00000292327.4
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_-_154164534 12.95 ENST00000271850.7
ENST00000368530.2
tropomyosin 3
chr7_-_44105158 12.81 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr11_+_1940925 12.40 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr11_+_1940786 11.79 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
troponin T type 3 (skeletal, fast)
chr4_-_186697044 11.69 ENST00000437304.2
sorbin and SH3 domain containing 2
chr2_+_170366203 11.15 ENST00000284669.1
kelch-like family member 41
chr1_-_201390846 11.12 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
troponin I type 1 (skeletal, slow)
chr4_+_169418195 10.49 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr10_+_88428206 10.19 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr14_-_23877474 9.90 ENST00000405093.3
myosin, heavy chain 6, cardiac muscle, alpha
chr8_+_1993152 8.72 ENST00000262113.4
myomesin 2
chr1_+_160160283 8.72 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160346 8.61 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr18_-_3220106 8.55 ENST00000356443.4
ENST00000400569.3
myomesin 1
chr20_+_43211149 8.12 ENST00000372886.1
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr8_+_1993173 8.07 ENST00000523438.1
myomesin 2
chr10_+_88428370 7.98 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LIM domain binding 3
chr8_-_33457453 7.86 ENST00000523956.1
ENST00000256261.4
dual specificity phosphatase 26 (putative)
chr1_-_116311402 7.36 ENST00000261448.5
calsequestrin 2 (cardiac muscle)
chr16_+_30075595 7.22 ENST00000563060.2
aldolase A, fructose-bisphosphate
chr16_+_30075463 7.17 ENST00000562168.1
ENST00000569545.1
aldolase A, fructose-bisphosphate
chr16_+_30075783 7.12 ENST00000412304.2
aldolase A, fructose-bisphosphate
chr3_+_193853927 7.11 ENST00000232424.3
hes family bHLH transcription factor 1
chr10_-_75415825 7.03 ENST00000394810.2
synaptopodin 2-like
chr1_-_31845914 6.83 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr19_+_35629702 6.53 ENST00000351325.4
FXYD domain containing ion transport regulator 1
chr4_-_88450612 6.43 ENST00000418378.1
ENST00000282470.6
SPARC-like 1 (hevin)
chr19_+_35630022 6.40 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr4_-_186696425 6.10 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr4_+_120056939 5.99 ENST00000307128.5
myozenin 2
chr1_+_156095951 5.85 ENST00000448611.2
ENST00000368297.1
lamin A/C
chr4_-_57547454 5.58 ENST00000556376.2
HOP homeobox
chr4_-_57547870 5.53 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr10_-_45474237 5.52 ENST00000448778.1
ENST00000298295.3
chromosome 10 open reading frame 10
chr19_+_6739662 5.50 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
thyroid hormone receptor interactor 10
chr4_+_55095264 5.46 ENST00000257290.5
platelet-derived growth factor receptor, alpha polypeptide
chr3_+_179370517 5.38 ENST00000263966.3
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr10_-_75410771 5.31 ENST00000372873.4
synaptopodin 2-like
chr3_+_127634312 5.30 ENST00000407609.3
kelch repeat and BTB (POZ) domain containing 12
chr3_+_127634069 5.18 ENST00000405109.1
kelch repeat and BTB (POZ) domain containing 12
chr5_+_53751445 5.11 ENST00000302005.1
heat shock 27kDa protein 3
chr19_+_35630344 5.05 ENST00000455515.2
FXYD domain containing ion transport regulator 1
chr5_+_140749803 4.90 ENST00000576222.1
protocadherin gamma subfamily B, 3
chr4_+_41362796 4.75 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr1_-_115238207 4.68 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
adenosine monophosphate deaminase 1
chr13_+_76334567 4.48 ENST00000321797.8
LIM domain 7
chr18_-_3219847 4.24 ENST00000261606.7
myomesin 1
chr16_+_84328252 4.21 ENST00000219454.5
WAP four-disulfide core domain 1
chr4_+_169418255 4.15 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr16_+_84328429 4.12 ENST00000568638.1
WAP four-disulfide core domain 1
chr13_+_76334795 3.86 ENST00000526202.1
ENST00000465261.2
LIM domain 7
chr1_+_156096336 3.83 ENST00000504687.1
ENST00000473598.2
lamin A/C
chr10_-_115423792 3.69 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
nebulin-related anchoring protein
chr21_+_27011584 3.67 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
junctional adhesion molecule 2
chr7_-_56160625 3.59 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
phosphorylase kinase, gamma 1 (muscle)
chr16_+_6069072 3.46 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr20_+_48807351 3.45 ENST00000303004.3
CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_23652849 3.28 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr20_+_44035847 3.19 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr14_+_74003818 3.06 ENST00000311148.4
acyl-CoA thioesterase 1
chr1_-_12677714 3.04 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr7_-_56160666 3.03 ENST00000297373.2
phosphorylase kinase, gamma 1 (muscle)
chr6_-_169654139 3.03 ENST00000366787.3
thrombospondin 2
chr11_-_47374246 2.89 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
myosin binding protein C, cardiac
chr3_+_138067521 2.87 ENST00000494949.1
muscle RAS oncogene homolog
chr3_+_159570722 2.83 ENST00000482804.1
schwannomin interacting protein 1
chr11_+_19799327 2.76 ENST00000540292.1
neuron navigator 2
chr3_-_192445289 2.70 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
fibroblast growth factor 12
chrX_+_153046456 2.69 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRSF protein kinase 3
chr4_+_41614909 2.61 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr9_+_100263912 2.55 ENST00000259365.4
tropomodulin 1
chr2_-_151344172 2.55 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr6_-_45983581 2.55 ENST00000339561.6
chloride intracellular channel 5
chr11_+_3666335 2.54 ENST00000250693.1
ADP-ribosyltransferase 1
chr15_+_42651691 2.45 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
calpain 3, (p94)
chr10_-_29923893 2.43 ENST00000355867.4
supervillin
chr2_-_190044480 2.40 ENST00000374866.3
collagen, type V, alpha 2
chr9_-_21995249 2.33 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr8_-_49834299 2.31 ENST00000396822.1
snail family zinc finger 2
chr8_-_49833978 2.26 ENST00000020945.1
snail family zinc finger 2
chr16_+_7382745 2.23 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_+_63661053 2.15 ENST00000279873.7
AT rich interactive domain 5B (MRF1-like)
chr18_+_9708162 2.11 ENST00000578921.1
RAB31, member RAS oncogene family
chr4_+_95373037 2.10 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDZ and LIM domain 5
chr7_-_150946015 2.09 ENST00000262188.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr17_-_10372875 2.05 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr14_-_61748550 2.05 ENST00000555868.1
transmembrane protein 30B
chr15_+_67418047 1.86 ENST00000540846.2
SMAD family member 3
chr3_+_4535155 1.86 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr2_+_30569506 1.67 ENST00000421976.2
AC109642.1
chr17_-_79604075 1.66 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
nuclear protein localization 4 homolog (S. cerevisiae)
chr21_+_39628655 1.60 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_39125365 1.60 ENST00000559001.1
ENST00000464276.2
POU class 6 homeobox 2
chr3_+_138067314 1.59 ENST00000423968.2
muscle RAS oncogene homolog
chr9_-_110251836 1.58 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr17_-_1389228 1.55 ENST00000438665.2
myosin IC
chr14_-_21493123 1.53 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr7_+_120629653 1.51 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr3_+_69928256 1.50 ENST00000394355.2
microphthalmia-associated transcription factor
chr21_-_42219065 1.47 ENST00000400454.1
Down syndrome cell adhesion molecule
chr7_+_30951461 1.47 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr7_-_151217001 1.47 ENST00000262187.5
Ras homolog enriched in brain
chr9_-_33402506 1.46 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
aquaporin 7
chr3_+_138067666 1.46 ENST00000475711.1
ENST00000464896.1
muscle RAS oncogene homolog
chr10_+_71561630 1.44 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr21_+_39628852 1.40 ENST00000398938.2
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_230513367 1.39 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr10_+_71561704 1.37 ENST00000520267.1
collagen, type XIII, alpha 1
chr17_-_10276319 1.34 ENST00000252172.4
ENST00000418404.3
myosin, heavy chain 13, skeletal muscle
chr2_+_145780767 1.31 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
testis expressed 41 (non-protein coding)
chr1_-_230850043 1.30 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_+_201979645 1.29 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_+_135741576 1.25 ENST00000334546.2
protein phosphatase 2, regulatory subunit B'', alpha
chr17_-_1389419 1.22 ENST00000575158.1
myosin IC
chr19_-_893200 1.21 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
mediator complex subunit 16
chr17_+_65040678 1.19 ENST00000226021.3
calcium channel, voltage-dependent, gamma subunit 1
chr3_+_36421826 1.18 ENST00000273183.3
SH3 and cysteine rich domain
chr9_+_5231413 1.13 ENST00000239316.4
insulin-like 4 (placenta)
chr17_-_42200958 1.11 ENST00000336057.5
histone deacetylase 5
chr1_-_201346761 1.10 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr18_+_29027696 1.01 ENST00000257189.4
desmoglein 3
chrX_-_30327495 0.95 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr18_+_3252206 0.94 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_18034701 0.94 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr10_+_71561649 0.86 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr10_+_32856764 0.85 ENST00000375030.2
ENST00000375028.3
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr1_+_170633047 0.84 ENST00000239461.6
ENST00000497230.2
paired related homeobox 1
chr1_-_59249732 0.84 ENST00000371222.2
jun proto-oncogene
chr2_+_173686303 0.80 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr17_-_42200996 0.80 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr2_-_148778323 0.78 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr2_+_233497931 0.76 ENST00000264059.3
EF-hand domain family, member D1
chr22_-_51016846 0.73 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr2_+_166152283 0.71 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chr1_+_145524891 0.69 ENST00000369304.3
integrin, alpha 10
chr7_-_82073109 0.65 ENST00000356860.3
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr3_-_38071122 0.64 ENST00000334661.4
phospholipase C, delta 1
chr1_+_92632542 0.62 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr1_-_173174681 0.62 ENST00000367718.1
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_62602327 0.58 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chr2_+_220143989 0.58 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr8_-_17533838 0.55 ENST00000400046.1
microtubule associated tumor suppressor 1
chr1_-_157014865 0.54 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr11_+_69924639 0.54 ENST00000538023.1
ENST00000398543.2
anoctamin 1, calcium activated chloride channel
chr19_-_1021113 0.53 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr10_+_71562180 0.46 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr1_-_713985 0.46 ENST00000428504.1
RP11-206L10.2
chr10_-_61900762 0.45 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_62704005 0.43 ENST00000337910.5
Rho-related BTB domain containing 1
chr7_-_82073031 0.43 ENST00000356253.5
ENST00000423588.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr7_+_154002189 0.42 ENST00000332007.3
dipeptidyl-peptidase 6
chr7_+_142457315 0.41 ENST00000486171.1
ENST00000311737.7
protease, serine, 1 (trypsin 1)
chr11_+_12766583 0.40 ENST00000361985.2
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_-_151217166 0.38 ENST00000496004.1
Ras homolog enriched in brain
chr22_-_51017084 0.35 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr3_-_11610255 0.32 ENST00000424529.2
vestigial like 4 (Drosophila)
chr5_-_115910630 0.30 ENST00000343348.6
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_46924829 0.29 ENST00000313049.5
parathyroid hormone 1 receptor
chr10_+_124134201 0.26 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_-_208030647 0.24 ENST00000309446.6
Kruppel-like factor 7 (ubiquitous)
chrX_+_9217932 0.24 ENST00000432442.1
GS1-519E5.1
chr2_+_109204743 0.23 ENST00000332345.6
LIM and senescent cell antigen-like domains 1
chr13_+_97928395 0.21 ENST00000445661.2
muscleblind-like splicing regulator 2
chr3_-_3151664 0.21 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
interleukin 5 receptor, alpha
chr3_+_113616317 0.19 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr7_+_5919458 0.17 ENST00000416608.1
oncomodulin
chr2_+_145780739 0.16 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
testis expressed 41 (non-protein coding)
chr10_+_121652204 0.16 ENST00000369075.3
ENST00000543134.1
SEC23 interacting protein
chr14_+_78870030 0.14 ENST00000553631.1
ENST00000554719.1
neurexin 3
chr1_+_221051699 0.14 ENST00000366903.6
H2.0-like homeobox
chr17_-_72855989 0.13 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr4_+_110834033 0.11 ENST00000509793.1
ENST00000265171.5
epidermal growth factor
chr1_-_40042416 0.11 ENST00000372857.3
ENST00000372856.3
ENST00000531243.2
ENST00000451091.2
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr22_+_45680822 0.09 ENST00000216211.4
ENST00000396082.2
uroplakin 3A
chr3_+_4535025 0.07 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr3_-_101039402 0.07 ENST00000193391.7
interphotoreceptor matrix proteoglycan 2
chr3_+_154797877 0.05 ENST00000462745.1
ENST00000493237.1
membrane metallo-endopeptidase
chr9_+_130565147 0.04 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
folylpolyglutamate synthase
chr1_+_41174988 0.04 ENST00000372652.1
nuclear transcription factor Y, gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.5 45.8 GO:0035995 detection of muscle stretch(GO:0035995)
5.6 22.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.9 19.6 GO:0099640 axo-dendritic protein transport(GO:0099640)
4.7 38.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
3.7 29.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
3.5 17.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
3.3 26.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
3.2 12.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
3.0 18.0 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
2.9 225.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
2.6 7.9 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
2.5 61.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
2.4 7.1 GO:0021558 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
2.3 6.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.9 9.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
1.8 5.5 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.5 4.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.4 7.0 GO:0071313 cellular response to caffeine(GO:0071313)
1.3 5.4 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.2 21.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 21.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.8 1.6 GO:0048867 stem cell fate determination(GO:0048867)
0.8 11.2 GO:2000291 regulation of pseudopodium assembly(GO:0031272) regulation of myoblast proliferation(GO:2000291)
0.7 14.6 GO:0003334 keratinocyte development(GO:0003334)
0.7 2.8 GO:0021564 vagus nerve development(GO:0021564)
0.7 14.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 20.7 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 2.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.6 32.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 20.6 GO:0045214 sarcomere organization(GO:0045214)
0.5 11.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.5 1.6 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.5 2.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.5 8.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 1.5 GO:0072019 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.5 1.9 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.5 4.7 GO:0032264 IMP salvage(GO:0032264)
0.5 2.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 1.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 2.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.3 0.6 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 2.7 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 1.5 GO:0015793 glycerol transport(GO:0015793)
0.3 3.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 2.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.8 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 3.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.8 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 6.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 2.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 0.9 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.2 1.1 GO:0098903 membrane depolarization during bundle of His cell action potential(GO:0086048) regulation of membrane repolarization during action potential(GO:0098903)
0.2 11.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 1.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 1.9 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 1.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.4 GO:0071286 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 3.3 GO:0015695 organic cation transport(GO:0015695)
0.1 5.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 2.3 GO:0030239 myofibril assembly(GO:0030239)
0.1 2.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 7.2 GO:0061045 negative regulation of wound healing(GO:0061045)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.1 2.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 2.1 GO:0016577 histone demethylation(GO:0016577)
0.1 2.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1 5.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 5.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 2.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 3.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 2.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 1.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 7.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0061053 somite development(GO:0061053)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 2.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 168.1 GO:0005861 troponin complex(GO:0005861)
3.9 15.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
3.5 38.0 GO:0097512 cardiac myofibril(GO:0097512)
3.4 20.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
2.4 79.5 GO:0005859 muscle myosin complex(GO:0005859)
2.2 24.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.1 9.7 GO:0005638 lamin filament(GO:0005638)
1.0 29.3 GO:0031143 pseudopodium(GO:0031143)
1.0 4.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.0 14.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.9 18.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 2.4 GO:0005588 collagen type V trimer(GO:0005588)
0.7 6.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 137.1 GO:0031674 I band(GO:0031674)
0.7 2.8 GO:0045160 myosin I complex(GO:0045160)
0.7 12.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 1.9 GO:0005955 calcineurin complex(GO:0005955)
0.6 3.7 GO:0005927 muscle tendon junction(GO:0005927)
0.5 1.5 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.4 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.3 2.4 GO:0036449 microtubule minus-end(GO:0036449)
0.3 5.5 GO:0001891 phagocytic cup(GO:0001891)
0.3 2.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 1.2 GO:0030315 T-tubule(GO:0030315)
0.2 3.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 11.0 GO:0016528 sarcoplasm(GO:0016528)
0.2 10.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 61.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 2.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.1 5.5 GO:0005902 microvillus(GO:0005902)
0.1 27.5 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 3.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 7.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 44.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
6.8 95.0 GO:0031014 troponin T binding(GO:0031014)
6.7 26.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
6.5 19.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
5.9 29.6 GO:0051373 FATZ binding(GO:0051373)
3.8 45.5 GO:0032036 myosin heavy chain binding(GO:0032036)
3.4 20.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.2 12.8 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
3.2 22.2 GO:0031433 telethonin binding(GO:0031433)
3.1 66.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
2.3 6.8 GO:0070538 oleic acid binding(GO:0070538)
2.0 26.1 GO:0005344 oxygen transporter activity(GO:0005344)
2.0 21.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 5.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.8 5.4 GO:1904288 BAT3 complex binding(GO:1904288)
1.7 9.9 GO:0017018 myosin phosphatase activity(GO:0017018)
1.6 7.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.7 6.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.7 17.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 1.1 GO:0030172 troponin C binding(GO:0030172)
0.5 38.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 2.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5 1.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.5 14.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5 1.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 3.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 8.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 1.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4 1.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.4 1.5 GO:0015254 glycerol channel activity(GO:0015254)
0.3 1.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 3.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 3.3 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 20.2 GO:0005254 chloride channel activity(GO:0005254)
0.2 6.2 GO:0000146 microfilament motor activity(GO:0000146)
0.2 57.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 2.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 46.2 GO:0003779 actin binding(GO:0003779)
0.1 1.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 6.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 9.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 15.8 GO:0044325 ion channel binding(GO:0044325)
0.1 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 7.4 GO:0051087 chaperone binding(GO:0051087)
0.1 4.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.1 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 26.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 9.6 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 4.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 12.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 38.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 19.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.2 23.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 7.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.5 PID INSULIN PATHWAY Insulin Pathway
0.1 2.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 7.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 9.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.9 ST GAQ PATHWAY G alpha q Pathway
0.0 2.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 260.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.1 55.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 6.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 19.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 4.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.5 REACTOME DEFENSINS Genes involved in Defensins
0.1 5.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 10.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 4.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 5.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor