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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MEIS3_TGIF2LX

Z-value: 0.20

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Transcription factors associated with MEIS3_TGIF2LX

Gene Symbol Gene ID Gene Info
MEIS3
ENSG00000105419.13 Meis homeobox 3
TGIF2LX
ENSG00000153779.8 TGFB induced factor homeobox 2 like X-linked

Activity profile of MEIS3_TGIF2LX motif

Sorted Z-values of MEIS3_TGIF2LX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_33447584 8.46 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr19_-_45826125 6.75 ENST00000221476.3
CKM
creatine kinase, muscle
chr3_-_49726486 6.74 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_-_153517473 6.45 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr17_+_41003166 6.41 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr2_-_242089677 6.37 ENST00000405260.1
PASK
PAS domain containing serine/threonine kinase
chr11_-_107590383 5.20 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr8_+_56014949 5.06 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr10_-_5060201 4.89 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr10_-_5060147 4.82 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr19_-_51531272 4.53 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr12_+_104458235 4.22 ENST00000229330.4
HCFC2
host cell factor C2
chr19_-_51530916 4.16 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr11_-_72070206 4.13 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr16_+_20818020 4.11 ENST00000564274.1
ENST00000563068.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr16_+_20817839 4.09 ENST00000348433.6
ENST00000568501.1
ENST00000566276.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr6_-_32557610 3.98 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr10_-_104597286 3.69 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr1_-_47655686 3.50 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr17_-_42345487 3.47 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr16_+_20817761 3.38 ENST00000568046.1
ENST00000261377.6
AC004381.6
Putative RNA exonuclease NEF-sp
chr19_-_51529849 3.34 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr17_-_19648916 3.17 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chrX_-_153775426 3.14 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr8_+_86351056 3.09 ENST00000285381.2
CA3
carbonic anhydrase III, muscle specific
chr2_+_90248739 3.02 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr16_+_1290694 3.01 ENST00000338844.3
TPSAB1
tryptase alpha/beta 1
chr17_+_7210294 2.99 ENST00000336452.7
EIF5A
eukaryotic translation initiation factor 5A
chr7_-_150675372 2.95 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_-_51531210 2.92 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr16_+_72090053 2.88 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP
haptoglobin
chr11_-_76381029 2.88 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr2_+_90139056 2.79 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr16_+_1290725 2.76 ENST00000461509.2
TPSAB1
tryptase alpha/beta 1
chr2_+_97202480 2.64 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr4_-_134070250 2.49 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr21_-_43735446 2.47 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr11_-_65325664 2.43 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr2_+_97203082 2.37 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_+_1942580 2.37 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr11_-_72145669 2.22 ENST00000543042.1
ENST00000294053.3
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr4_+_69313145 2.20 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr1_+_158325684 2.18 ENST00000368162.2
CD1E
CD1e molecule
chr1_-_155162658 2.14 ENST00000368389.2
ENST00000368396.4
ENST00000343256.5
ENST00000342482.4
ENST00000368398.3
ENST00000368390.3
ENST00000337604.5
ENST00000368392.3
ENST00000438413.1
ENST00000368393.3
ENST00000457295.2
ENST00000338684.5
ENST00000368395.1
MUC1
mucin 1, cell surface associated
chr11_-_2170786 2.07 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_-_89597542 2.00 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr17_+_58755184 1.95 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr16_+_30212378 1.94 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_-_153013588 1.94 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr10_+_104535994 1.91 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr4_-_40517984 1.88 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr1_-_201081579 1.88 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr3_-_133748913 1.85 ENST00000310926.4
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr9_+_136501478 1.84 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr11_+_117947782 1.83 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
TMPRSS4
transmembrane protease, serine 4
chr2_+_220379052 1.83 ENST00000347842.3
ENST00000358078.4
ASIC4
acid-sensing (proton-gated) ion channel family member 4
chr11_+_117947724 1.81 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr17_-_41465674 1.79 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr16_+_1306060 1.78 ENST00000397534.2
TPSD1
tryptase delta 1
chr16_+_67360712 1.69 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr2_-_61697862 1.67 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr7_+_2599056 1.61 ENST00000325979.7
ENST00000423395.1
IQCE
IQ motif containing E
chr5_-_58882219 1.58 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_76139833 1.57 ENST00000257632.5
UPK3B
uroplakin 3B
chr3_+_49726932 1.53 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
RNF123
ring finger protein 123
chr1_-_169680745 1.52 ENST00000236147.4
SELL
selectin L
chr17_+_34431212 1.50 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr4_+_175839506 1.46 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM29
ADAM metallopeptidase domain 29
chr1_-_116383738 1.45 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr3_+_111260954 1.43 ENST00000283285.5
CD96
CD96 molecule
chr10_-_105212141 1.42 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr17_+_18380051 1.39 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr17_-_1395954 1.38 ENST00000359786.5
MYO1C
myosin IC
chr7_+_76139741 1.38 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chr4_+_175839551 1.36 ENST00000404450.4
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr7_-_29234802 1.35 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr10_-_105212059 1.34 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr2_-_24149977 1.34 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr10_+_104503727 1.29 ENST00000448841.1
WBP1L
WW domain binding protein 1-like
chrX_+_47420516 1.28 ENST00000377045.4
ENST00000290277.6
ENST00000377039.2
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr3_+_111260856 1.27 ENST00000352690.4
CD96
CD96 molecule
chr16_-_32688053 1.24 ENST00000398682.4
TP53TG3
TP53 target 3
chr3_+_8775466 1.19 ENST00000343849.2
ENST00000397368.2
CAV3
caveolin 3
chr22_+_39052632 1.14 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr11_-_76381781 1.13 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr16_+_29789561 1.09 ENST00000400752.4
ZG16
zymogen granule protein 16
chr14_-_67859422 1.07 ENST00000556532.1
PLEK2
pleckstrin 2
chr17_+_33448593 1.06 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr3_-_12883026 1.05 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
RPL32
ribosomal protein L32
chr7_+_76139925 1.04 ENST00000394849.1
UPK3B
uroplakin 3B
chr1_-_54872059 1.03 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr19_+_5455421 1.02 ENST00000222033.4
ZNRF4
zinc and ring finger 4
chr5_+_15500280 1.01 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr6_-_33160231 1.01 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr18_+_76829385 0.99 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATP9B
ATPase, class II, type 9B
chr16_+_32264040 0.95 ENST00000398664.3
TP53TG3D
TP53 target 3D
chr19_-_41256207 0.94 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr1_-_21113105 0.93 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3
heterochromatin protein 1, binding protein 3
chr6_+_160769399 0.89 ENST00000392145.1
SLC22A3
solute carrier family 22 (organic cation transporter), member 3
chr2_+_90458201 0.88 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr12_+_100867694 0.87 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_+_155753745 0.86 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr11_-_615570 0.85 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr6_-_30128657 0.85 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr3_-_130745571 0.83 ENST00000514044.1
ENST00000264992.3
ASTE1
asteroid homolog 1 (Drosophila)
chr7_-_7782204 0.82 ENST00000418534.2
AC007161.5
AC007161.5
chr19_+_5623186 0.82 ENST00000538656.1
SAFB
scaffold attachment factor B
chr1_+_154975110 0.80 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr19_+_6361841 0.80 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr6_+_24495185 0.80 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr2_-_198299726 0.80 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
SF3B1
splicing factor 3b, subunit 1, 155kDa
chr1_+_86934526 0.77 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr2_+_162087577 0.77 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr6_+_160769300 0.76 ENST00000275300.2
SLC22A3
solute carrier family 22 (organic cation transporter), member 3
chr16_-_20364122 0.76 ENST00000396138.4
ENST00000577168.1
UMOD
uromodulin
chr22_-_31885514 0.75 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chrX_-_11445856 0.74 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr9_+_135854091 0.74 ENST00000450530.1
ENST00000534944.1
GFI1B
growth factor independent 1B transcription repressor
chr19_+_6361754 0.71 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr12_-_53298841 0.71 ENST00000293308.6
KRT8
keratin 8
chr17_+_34538310 0.70 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr22_+_46731596 0.70 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr7_-_99332719 0.70 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr19_+_17982747 0.70 ENST00000222248.3
SLC5A5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr19_-_40791211 0.70 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chrX_+_153775821 0.69 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr5_-_131329918 0.69 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr11_+_63304273 0.68 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr7_+_5919458 0.68 ENST00000416608.1
OCM
oncomodulin
chr17_+_39846114 0.67 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr7_+_2598628 0.66 ENST00000402050.2
ENST00000404984.1
ENST00000415271.2
ENST00000438376.2
IQCE
IQ motif containing E
chr17_-_39780819 0.65 ENST00000311208.8
KRT17
keratin 17
chr16_-_20364030 0.65 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD
uromodulin
chr16_+_56899114 0.61 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3
solute carrier family 12 (sodium/chloride transporter), member 3
chr20_-_3644046 0.60 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr5_-_131330272 0.60 ENST00000379240.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr11_+_86511569 0.59 ENST00000441050.1
PRSS23
protease, serine, 23
chrX_+_135730373 0.59 ENST00000370628.2
CD40LG
CD40 ligand
chr12_+_100867486 0.59 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr13_-_41837620 0.59 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr12_+_121647868 0.58 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr9_-_99540328 0.57 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
ZNF510
zinc finger protein 510
chrX_+_135730297 0.54 ENST00000370629.2
CD40LG
CD40 ligand
chr13_+_78109804 0.52 ENST00000535157.1
SCEL
sciellin
chr13_+_78109884 0.52 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr4_+_128554081 0.52 ENST00000335251.6
ENST00000296461.5
INTU
inturned planar cell polarity protein
chr7_+_29234375 0.52 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
CHN2
chimerin 2
chr18_+_3449821 0.51 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr19_+_6361795 0.51 ENST00000596149.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr9_-_22009297 0.51 ENST00000276925.6
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr18_+_55018044 0.50 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_+_18287721 0.50 ENST00000356524.4
SAA1
serum amyloid A1
chr19_+_12273866 0.49 ENST00000425827.1
ENST00000439995.1
ENST00000343979.4
ENST00000398616.2
ENST00000418338.1
ZNF136
zinc finger protein 136
chr11_+_18287801 0.49 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chrX_+_150863596 0.48 ENST00000448726.1
ENST00000538575.1
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr19_-_10227503 0.47 ENST00000593054.1
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr10_-_79398127 0.46 ENST00000372443.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_-_33446735 0.45 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr7_-_128415844 0.45 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr10_+_28822636 0.44 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr18_-_54318353 0.43 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr11_+_128634589 0.42 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_80677815 0.41 ENST00000557125.1
ENST00000555750.1
DIO2
deiodinase, iodothyronine, type II
chr7_-_156803329 0.41 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr11_+_67776012 0.40 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr13_-_99174252 0.39 ENST00000376547.3
STK24
serine/threonine kinase 24
chr9_+_131843377 0.39 ENST00000372546.4
ENST00000406974.3
ENST00000540102.1
DOLPP1
dolichyldiphosphatase 1
chrX_+_17755563 0.38 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr1_+_154975258 0.38 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr12_+_121647962 0.36 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr9_-_22009241 0.36 ENST00000380142.4
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr19_+_35773242 0.36 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr3_-_122512619 0.35 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr11_-_101000445 0.34 ENST00000534013.1
PGR
progesterone receptor
chr1_+_168250194 0.33 ENST00000367821.3
TBX19
T-box 19
chr22_+_21369316 0.32 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr3_+_130745688 0.32 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
NEK11
NIMA-related kinase 11
chr8_-_61880248 0.31 ENST00000525556.1
AC022182.3
AC022182.3
chr1_+_100598691 0.30 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr15_+_85427903 0.30 ENST00000286749.3
ENST00000394573.1
ENST00000537703.1
SLC28A1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr17_-_33446820 0.29 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51D
RAD51 paralog D
chr16_+_1306093 0.28 ENST00000211076.3
TPSD1
tryptase delta 1
chr13_+_33160553 0.26 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr17_-_5015129 0.26 ENST00000575898.1
ENST00000416429.2
ZNF232
zinc finger protein 232
chr2_-_65593784 0.26 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr11_-_82745238 0.26 ENST00000531021.1
RAB30
RAB30, member RAS oncogene family
chr13_+_48877895 0.24 ENST00000267163.4
RB1
retinoblastoma 1
chr17_+_73089382 0.24 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr9_+_34990219 0.23 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_+_24714729 0.23 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr2_+_219524473 0.22 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr11_-_842509 0.21 ENST00000322028.4
POLR2L
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr17_+_57232690 0.20 ENST00000262293.4
PRR11
proline rich 11
chr3_+_130745769 0.20 ENST00000412440.2
NEK11
NIMA-related kinase 11
chr19_-_4670345 0.20 ENST00000599630.1
ENST00000262947.3
C19orf10
chromosome 19 open reading frame 10
chr18_-_52989525 0.19 ENST00000457482.3
TCF4
transcription factor 4
chr16_-_2004683 0.19 ENST00000268661.7
RPL3L
ribosomal protein L3-like
chr1_+_144151520 0.19 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chrY_-_2655644 0.18 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
SRY
sex determining region Y
chr22_+_44319619 0.17 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS3_TGIF2LX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.7 8.5 GO:0070295 renal water absorption(GO:0070295)
1.4 9.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.0 6.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
1.0 3.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
1.0 2.9 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.0 2.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.9 2.7 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.8 4.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.6 6.8 GO:0006600 creatine metabolic process(GO:0006600)
0.6 2.4 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.5 1.5 GO:0001080 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.4 6.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.4 3.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 1.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 1.4 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.3 1.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.3 1.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.3 2.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.3 1.0 GO:0060023 soft palate development(GO:0060023)
0.3 4.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.7 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 3.7 GO:0006702 androgen biosynthetic process(GO:0006702)
0.2 1.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 2.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.2 0.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.2 6.4 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.2 1.9 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 2.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 1.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.8 GO:0015732 prostaglandin transport(GO:0015732)
0.1 1.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:1904479 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 6.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.6 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.0 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.7 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 1.6 GO:0051608 histamine transport(GO:0051608)
0.1 0.7 GO:0015705 iodide transport(GO:0015705)
0.1 0.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.6 GO:0006449 regulation of translational termination(GO:0006449)
0.1 1.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.5 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.3 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 4.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 1.8 GO:0033198 response to ATP(GO:0033198)
0.1 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.3 GO:0006540 glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.5 GO:0034465 response to carbon monoxide(GO:0034465) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.9 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.9 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 2.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 5.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 6.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 5.8 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 5.7 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 2.5 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0048679 regulation of axon regeneration(GO:0048679)
0.0 1.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.2 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.0 0.7 GO:0043276 anoikis(GO:0043276)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.5 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 2.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 27.3 GO:0006508 proteolysis(GO:0006508)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 2.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 2.0 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.3 1.4 GO:0045160 myosin I complex(GO:0045160)
0.2 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.2 4.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 5.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.4 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 6.2 GO:0005902 microvillus(GO:0005902)
0.1 1.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.0 GO:0001533 cornified envelope(GO:0001533)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 12.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0005686 U2 snRNP(GO:0005686) U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 2.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 37.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.7 GO:0030424 axon(GO:0030424)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
2.1 8.5 GO:0015254 glycerol channel activity(GO:0015254)
1.6 9.7 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
1.0 3.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.8 6.8 GO:0004111 creatine kinase activity(GO:0004111)
0.6 1.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.6 3.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6 2.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 2.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 1.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.5 2.9 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.9 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 6.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 1.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.2 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2 1.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.6 GO:0005329 dopamine transmembrane transporter activity(GO:0005329) quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.2 3.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 3.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 4.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 3.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.1 1.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 40.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 4.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.4 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.1 1.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.4 GO:0019864 IgG binding(GO:0019864)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 2.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.7 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 2.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 5.5 GO:0051117 ATPase binding(GO:0051117)
0.0 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 1.8 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 3.0 GO:0003823 antigen binding(GO:0003823)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0004518 nuclease activity(GO:0004518)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 3.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0002039 p53 binding(GO:0002039)
0.0 2.8 GO:0005261 cation channel activity(GO:0005261)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 4.9 GO:0016887 ATPase activity(GO:0016887)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 7.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 21.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 3.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 3.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 2.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 6.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 3.1 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates