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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 0.93

Motif logo

Transcription factors associated with MIXL1_GSX1_BSX_MEOX2_LHX4

Gene Symbol Gene ID Gene Info
ENSG00000185155.7 Mix paired-like homeobox
ENSG00000169840.4 GS homeobox 1
ENSG00000188909.4 brain specific homeobox
ENSG00000106511.5 mesenchyme homeobox 2
ENSG00000121454.4 LIM homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MIXL1hg19_v2_chr1_+_226411319_2264113660.161.7e-02Click!
MEOX2hg19_v2_chr7_-_15726296_157264370.054.9e-01Click!

Activity profile of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Sorted Z-values of MIXL1_GSX1_BSX_MEOX2_LHX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_13835147 34.84 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr11_-_117748138 34.05 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr11_-_117747607 32.29 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr11_-_117747434 31.51 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr2_+_90248739 22.24 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr2_+_68962014 17.73 ENST00000467265.1
Rho GTPase activating protein 25
chr16_-_4852915 16.49 ENST00000322048.7
rogdi homolog (Drosophila)
chr5_+_66300446 16.06 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr18_+_32556892 15.56 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr3_-_18480260 15.50 ENST00000454909.2
SATB homeobox 1
chr2_+_68961934 15.41 ENST00000409202.3
Rho GTPase activating protein 25
chr13_-_46716969 15.14 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_111794446 15.12 ENST00000527950.1
crystallin, alpha B
chr2_+_68961905 15.06 ENST00000295381.3
Rho GTPase activating protein 25
chr12_-_6233828 14.88 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr4_+_40198527 14.01 ENST00000381799.5
ras homolog family member H
chr6_-_32908765 13.94 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr6_-_32908792 13.78 ENST00000418107.2
major histocompatibility complex, class II, DM beta
chr2_-_158300556 12.38 ENST00000264192.3
cytohesin 1 interacting protein
chr11_-_33913708 12.38 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr12_+_81110684 12.15 ENST00000228644.3
myogenic factor 5
chr2_-_89340242 11.85 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr3_+_111718036 11.47 ENST00000455401.2
transgelin 3
chr18_+_71815743 10.67 ENST00000169551.6
ENST00000580087.1
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr3_+_111717600 10.60 ENST00000273368.4
transgelin 3
chr3_+_111718173 10.51 ENST00000494932.1
transgelin 3
chr5_+_156696362 10.45 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chrX_+_13671225 10.39 ENST00000545566.1
ENST00000544987.1
ENST00000314720.4
transcription elongation factor A (SII) N-terminal and central domain containing
chr2_+_90273679 10.28 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr3_-_39321512 10.14 ENST00000399220.2
chemokine (C-X3-C motif) receptor 1
chr2_-_136288113 10.05 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr13_-_88323218 10.01 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500 host gene (non-protein coding)
chr3_+_35722487 9.95 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr3_+_111717511 9.91 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr1_+_111415757 9.89 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr2_+_90211643 9.81 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr8_-_27468842 9.58 ENST00000523500.1
clusterin
chr5_-_24645078 9.51 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr11_-_129062093 9.35 ENST00000310343.9
Rho GTPase activating protein 32
chr6_+_151042224 9.16 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr1_+_174844645 9.14 ENST00000486220.1
RAB GTPase activating protein 1-like
chr4_-_46911248 8.90 ENST00000355591.3
ENST00000505102.1
cytochrome c oxidase subunit VIIb2
chr6_-_152639479 8.76 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr19_+_50016610 8.60 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr1_-_92952433 8.57 ENST00000294702.5
growth factor independent 1 transcription repressor
chr4_-_87028478 8.56 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr8_+_28748765 8.51 ENST00000355231.5
homeobox containing 1
chr3_+_115342349 8.35 ENST00000393780.3
growth associated protein 43
chr1_-_150738261 8.33 ENST00000448301.2
ENST00000368985.3
cathepsin S
chr11_+_121447469 8.27 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_108541545 8.22 ENST00000295756.6
T cell receptor associated transmembrane adaptor 1
chr5_+_36608422 8.21 ENST00000381918.3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_208031943 8.19 ENST00000421199.1
ENST00000457962.1
Kruppel-like factor 7 (ubiquitous)
chr2_+_196313239 8.12 ENST00000413290.1
AC064834.1
chr11_-_5255861 8.11 ENST00000380299.3
hemoglobin, delta
chr3_+_108541608 8.06 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chrX_-_19988382 7.97 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
chromosome X open reading frame 23
chr4_-_120243545 7.90 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr11_-_104972158 7.80 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr12_-_16761007 7.64 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr10_-_71169031 7.63 ENST00000373307.1
tachykinin receptor 2
chr4_-_170897045 7.61 ENST00000508313.1
RP11-205M3.3
chr1_-_152386732 7.52 ENST00000271835.3
cornulin
chr6_+_31583761 7.42 ENST00000376049.4
allograft inflammatory factor 1
chr12_-_112123524 7.41 ENST00000327551.6
BRCA1 associated protein
chr2_+_103035102 7.26 ENST00000264260.2
interleukin 18 receptor accessory protein
chr13_-_99910673 7.25 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr18_+_32558208 7.06 ENST00000436190.2
microtubule-associated protein, RP/EB family, member 2
chr14_-_101295407 7.04 ENST00000596284.1
AL117190.2
chr3_+_35721106 7.00 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr1_+_198608146 6.86 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr7_+_50348268 6.79 ENST00000438033.1
ENST00000439701.1
IKAROS family zinc finger 1 (Ikaros)
chr11_-_108093329 6.73 ENST00000278612.8
nuclear protein, ataxia-telangiectasia locus
chr2_+_169926047 6.70 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chr21_-_42219065 6.55 ENST00000400454.1
Down syndrome cell adhesion molecule
chr12_-_16759711 6.47 ENST00000447609.1
LIM domain only 3 (rhombotin-like 2)
chr12_+_26348246 6.45 ENST00000422622.2
sarcospan
chr2_-_89292422 6.43 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr2_-_89399845 6.35 ENST00000479981.1
immunoglobulin kappa variable 1-16
chrX_-_13835461 6.35 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr12_-_91546926 6.35 ENST00000550758.1
decorin
chr20_+_45947246 6.33 ENST00000599904.1
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr16_+_8768422 6.32 ENST00000268251.8
ENST00000564714.1
4-aminobutyrate aminotransferase
chr1_+_101003687 6.28 ENST00000315033.4
G protein-coupled receptor 88
chrX_-_73512411 6.25 ENST00000602576.1
ENST00000429124.1
FTX transcript, XIST regulator (non-protein coding)
chr14_+_61654271 6.17 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr8_+_117950422 6.11 ENST00000378279.3
alanine and arginine rich domain containing protein
chr12_-_114841703 6.01 ENST00000526441.1
T-box 5
chr8_-_90769422 5.93 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
chrX_-_92928557 5.91 ENST00000373079.3
ENST00000475430.2
nucleosome assembly protein 1-like 3
chr4_+_88754113 5.89 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr6_-_39693111 5.84 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
kinesin family member 6
chr12_-_15103621 5.76 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_28129795 5.68 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr2_-_89327228 5.68 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr14_+_22977587 5.65 ENST00000390504.1
T cell receptor alpha joining 33
chr18_+_29027696 5.59 ENST00000257189.4
desmoglein 3
chr18_-_5396271 5.58 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr10_+_18549645 5.53 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr16_+_22501658 5.49 ENST00000415833.2
nuclear pore complex interacting protein family, member B5
chr13_-_41593425 5.48 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr6_-_52705641 5.45 ENST00000370989.2
glutathione S-transferase alpha 5
chrX_+_55478538 5.37 ENST00000342972.1
melanoma antigen family H, 1
chr5_-_39219641 5.37 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr1_+_180601139 5.35 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr7_+_97361218 5.33 ENST00000319273.5
tachykinin, precursor 1
chr8_-_86253888 5.27 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr13_-_36788718 5.26 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr14_+_22337014 5.19 ENST00000390436.2
T cell receptor alpha variable 13-1
chr2_+_113763031 5.09 ENST00000259211.6
interleukin 36, alpha
chr1_+_84609944 5.09 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_128894053 5.02 ENST00000392657.3
Rho GTPase activating protein 32
chr7_+_149535455 4.95 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chr8_-_27469196 4.92 ENST00000546343.1
ENST00000560566.1
clusterin
chrM_+_12331 4.92 ENST00000361567.2
mitochondrially encoded NADH dehydrogenase 5
chrX_-_73512177 4.89 ENST00000603672.1
ENST00000418855.1
FTX transcript, XIST regulator (non-protein coding)
chr12_+_25205568 4.84 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr6_-_25042231 4.83 ENST00000510784.2
family with sequence similarity 65, member B
chr19_-_7968427 4.81 ENST00000539278.1
Uncharacterized protein
chrX_-_138724994 4.79 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr1_-_25291475 4.69 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr4_-_89205879 4.67 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr10_-_50970322 4.66 ENST00000374103.4
oxoglutarate dehydrogenase-like
chr16_-_66584059 4.62 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr1_+_117963209 4.61 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr17_+_45000483 4.59 ENST00000576910.2
ENST00000439730.2
ENST00000393456.2
ENST00000415811.2
ENST00000575949.1
ENST00000225567.4
ENST00000572403.1
ENST00000570879.1
golgi SNAP receptor complex member 2
chr7_+_100136811 4.56 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr1_+_84630645 4.53 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_57547870 4.52 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr1_+_36789335 4.46 ENST00000373137.2
RP11-268J15.5
chr6_-_32557610 4.45 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr14_-_106926724 4.44 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr4_-_57524061 4.41 ENST00000508121.1
HOP homeobox
chr14_+_22931924 4.41 ENST00000390477.2
T cell receptor delta constant
chrX_+_37639264 4.38 ENST00000378588.4
cytochrome b-245, beta polypeptide
chr12_+_56325812 4.31 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
diacylglycerol kinase, alpha 80kDa
chr2_+_90077680 4.29 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr6_-_170101749 4.28 ENST00000448612.1
WD repeat domain 27
chr2_-_50574856 4.22 ENST00000342183.5
neurexin 1
chr9_-_95166841 4.21 ENST00000262551.4
osteoglycin
chr6_+_72926145 4.20 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr4_-_57547454 4.16 ENST00000556376.2
HOP homeobox
chr19_-_53758094 4.15 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
zinc finger protein 677
chr7_-_73038822 4.14 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chr11_-_104905840 4.08 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr13_+_49551020 4.08 ENST00000541916.1
fibronectin type III domain containing 3A
chr8_-_102803163 4.06 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr18_-_53177984 4.04 ENST00000543082.1
transcription factor 4
chr5_+_54398463 3.99 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr6_+_26365443 3.93 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr5_+_176853702 3.92 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
G protein-coupled receptor kinase 6
chr6_-_32784687 3.92 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr1_-_48937821 3.92 ENST00000396199.3
spermatogenesis associated 6
chr12_-_23737534 3.91 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr4_-_176733897 3.90 ENST00000393658.2
glycoprotein M6A
chr2_-_89442621 3.90 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr18_+_32173276 3.90 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr1_-_45956822 3.89 ENST00000372086.3
ENST00000341771.6
testis-specific kinase 2
chr14_-_104181771 3.87 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
X-ray repair complementing defective repair in Chinese hamster cells 3
chr7_-_73038867 3.85 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLX interacting protein-like
chr17_-_9929581 3.84 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr8_+_38585704 3.84 ENST00000519416.1
ENST00000520615.1
transforming, acidic coiled-coil containing protein 1
chr10_+_18629628 3.79 ENST00000377329.4
calcium channel, voltage-dependent, beta 2 subunit
chr13_-_41706864 3.76 ENST00000379485.1
ENST00000499385.2
kelch repeat and BTB (POZ) domain containing 6
chr8_-_101571964 3.75 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ankyrin repeat domain 46
chr13_+_31309645 3.75 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr7_-_37488834 3.74 ENST00000310758.4
engulfment and cell motility 1
chr12_-_118796910 3.72 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr1_+_183774240 3.71 ENST00000360851.3
ral guanine nucleotide dissociation stimulator-like 1
chr3_-_98241358 3.71 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
claudin domain containing 1
chr12_-_30887948 3.70 ENST00000433722.2
caprin family member 2
chr7_+_97361388 3.69 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr1_-_48937838 3.69 ENST00000371847.3
spermatogenesis associated 6
chr12_-_10282836 3.68 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr6_-_22297730 3.68 ENST00000306482.1
prolactin
chrX_+_77166172 3.68 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr6_+_26402517 3.67 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr8_+_119294456 3.67 ENST00000366457.2
Uncharacterized protein
chr12_-_22063787 3.66 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr10_+_13142075 3.63 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
optineurin
chr8_-_87755878 3.63 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr10_-_115904361 3.63 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chrX_+_37639302 3.62 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr4_+_3388057 3.59 ENST00000538395.1
regulator of G-protein signaling 12
chrX_+_15808569 3.59 ENST00000380308.3
ENST00000307771.7
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr9_-_95166884 3.58 ENST00000375561.5
osteoglycin
chr6_-_32157947 3.58 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr4_+_88754069 3.55 ENST00000395102.4
ENST00000497649.2
matrix extracellular phosphoglycoprotein
chr9_-_21368075 3.54 ENST00000449498.1
interferon, alpha 13
chr7_-_137028534 3.53 ENST00000348225.2
pleiotrophin
chr1_-_160681593 3.50 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr4_-_89205705 3.48 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr18_-_21977748 3.47 ENST00000399441.4
ENST00000319481.3
oxysterol binding protein-like 1A
chr6_+_28317685 3.45 ENST00000252211.2
ENST00000341464.5
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr13_-_46626847 3.42 ENST00000242848.4
ENST00000282007.3
zinc finger CCCH-type containing 13
chr7_-_105029812 3.41 ENST00000482897.1
SRSF protein kinase 2
chr12_+_7014064 3.39 ENST00000443597.2
leucine rich repeat containing 23
chr12_-_9760482 3.39 ENST00000229402.3
killer cell lectin-like receptor subfamily B, member 1
chr7_-_87342564 3.38 ENST00000265724.3
ENST00000416177.1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr7_-_137028498 3.36 ENST00000393083.2
pleiotrophin

Network of associatons between targets according to the STRING database.

First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 27.7 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
4.3 42.7 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.4 10.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.0 9.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
3.0 11.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.9 22.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
2.9 8.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.8 8.3 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
2.5 7.6 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.4 14.5 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
2.4 14.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.3 6.9 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
2.1 14.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.0 10.1 GO:0048478 replication fork protection(GO:0048478)
2.0 6.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.9 9.6 GO:0097338 response to clozapine(GO:0097338)
1.7 13.4 GO:0007258 JUN phosphorylation(GO:0007258)
1.6 4.9 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
1.6 11.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.6 6.4 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
1.6 8.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.6 6.3 GO:0061743 motor learning(GO:0061743)
1.6 9.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.5 7.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
1.5 4.4 GO:0002399 MHC class II protein complex assembly(GO:0002399)
1.4 5.8 GO:0071461 cellular response to redox state(GO:0071461)
1.4 22.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.4 6.9 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
1.3 9.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.3 3.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.3 10.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.3 6.5 GO:0035063 nuclear speck organization(GO:0035063)
1.3 3.9 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.3 98.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
1.3 2.5 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.2 3.7 GO:0071284 cellular response to lead ion(GO:0071284)
1.2 1.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.1 4.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.1 8.0 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
1.1 3.3 GO:0002384 hepatic immune response(GO:0002384)
1.1 3.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.0 3.1 GO:0051697 protein delipidation(GO:0051697)
1.0 10.2 GO:0016198 axon choice point recognition(GO:0016198)
1.0 7.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.0 12.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.0 3.0 GO:0048382 mesendoderm development(GO:0048382)
1.0 6.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.9 17.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.9 13.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.9 4.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.9 9.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.9 2.6 GO:1904647 response to rotenone(GO:1904647)
0.9 1.7 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.9 6.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.8 15.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.8 1.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.8 10.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.8 3.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.8 20.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.8 4.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.8 6.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.8 4.6 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.8 2.3 GO:1902956 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of cellular respiration(GO:1901857) regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.8 2.3 GO:0019417 sulfur oxidation(GO:0019417)
0.7 2.2 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.7 5.7 GO:0070475 rRNA base methylation(GO:0070475)
0.7 4.8 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.7 2.0 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.7 2.0 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.7 12.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.7 3.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.6 1.9 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.6 1.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.6 6.7 GO:0042908 xenobiotic transport(GO:0042908)
0.6 0.6 GO:0070662 mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.6 1.2 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.6 6.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 1.8 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.6 13.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.6 2.3 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.6 2.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.6 2.8 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.6 1.7 GO:0001694 histamine biosynthetic process(GO:0001694)
0.6 2.2 GO:0072166 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.6 2.8 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.6 1.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.5 8.1 GO:0015671 oxygen transport(GO:0015671)
0.5 2.6 GO:0010958 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.5 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.5 2.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.5 1.6 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.5 6.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.5 1.5 GO:0044771 meiotic cell cycle phase transition(GO:0044771) establishment of meiotic spindle localization(GO:0051295) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 5.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 1.0 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.5 3.9 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.5 0.5 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.5 1.9 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.5 2.4 GO:1904823 pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.5 2.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.5 1.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.5 2.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 0.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 9.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.5 10.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.5 4.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.4 2.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.4 1.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4 1.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.4 3.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.4 8.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.4 13.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 3.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.4 59.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 1.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 7.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.4 1.6 GO:0060023 soft palate development(GO:0060023)
0.4 1.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.4 3.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 0.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4 0.7 GO:0015074 DNA integration(GO:0015074)
0.4 3.0 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 0.4 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.4 2.5 GO:1903232 melanosome assembly(GO:1903232)
0.4 1.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.4 5.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 2.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.4 9.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 0.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.3 0.3 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 2.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.3 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 2.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.0 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.3 6.9 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.3 1.6 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 1.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 3.9 GO:1902260 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.3 1.6 GO:0050955 thermoception(GO:0050955)
0.3 1.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3 5.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 5.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 3.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 2.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 2.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.3 2.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.3 2.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 1.5 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3 1.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.3 4.6 GO:0042832 defense response to protozoan(GO:0042832)
0.3 2.0 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.3 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.4 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.3 2.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.3 1.1 GO:0036269 swimming behavior(GO:0036269)
0.3 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 3.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 14.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.3 1.6 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.3 1.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.3 4.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.3 0.8 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.3 3.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 2.0 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 5.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 1.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.7 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 0.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 2.9 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.7 GO:0046849 bone remodeling(GO:0046849)
0.2 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 6.5 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.7 GO:0001764 neuron migration(GO:0001764)
0.2 2.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 2.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 0.5 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 1.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 2.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 1.1 GO:0006265 DNA topological change(GO:0006265)
0.2 4.1 GO:0060009 Sertoli cell development(GO:0060009)
0.2 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 7.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 1.6 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.4 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 2.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 1.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 2.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 1.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 72.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.2 3.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.6 GO:0021764 amygdala development(GO:0021764)
0.2 1.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 0.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.2 27.5 GO:0002377 immunoglobulin production(GO:0002377)
0.2 5.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 2.9 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.2 1.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.5 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 0.9 GO:0046618 drug export(GO:0046618)
0.2 9.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 1.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 5.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 2.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 0.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.7 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.2 11.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.2 0.6 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.9 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 6.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 0.5 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.2 1.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.8 GO:0001823 mesonephros development(GO:0001823)
0.1 0.6 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.1 3.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.6 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.1 2.0 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 5.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.4 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 21.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.4 GO:0072144 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 2.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 1.9 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.1 2.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.1 16.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 2.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 0.7 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.0 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.7 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 3.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.7 GO:0030324 lung development(GO:0030324)
0.1 2.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 3.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 3.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 1.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.9 GO:0051412 response to corticosterone(GO:0051412)
0.1 0.2 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.9 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 2.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 1.9 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.6 GO:0006955 immune response(GO:0006955)
0.1 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 1.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:0072488 carnitine shuttle(GO:0006853) ammonium transmembrane transport(GO:0072488) carnitine transmembrane transport(GO:1902603)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 1.0 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.3 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.3 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 2.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.3 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 1.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 10.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.5 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.2 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.6 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.2 GO:0048840 otolith development(GO:0048840)
0.1 1.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.4 GO:0046606 negative regulation of centrosome cycle(GO:0046606)
0.1 0.4 GO:0010927 cellular component assembly involved in morphogenesis(GO:0010927)
0.1 7.5 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.8 GO:0032196 transposition(GO:0032196)
0.1 4.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.6 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.1 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.2 GO:0038001 paracrine signaling(GO:0038001)
0.1 1.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.4 GO:0097421 liver regeneration(GO:0097421)
0.1 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.1 1.6 GO:0097503 sialylation(GO:0097503)
0.1 0.8 GO:0050890 cognition(GO:0050890)
0.1 0.8 GO:0007625 grooming behavior(GO:0007625)
0.1 2.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 5.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.8 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.8 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 6.4 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.5 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0045176 apical protein localization(GO:0045176)
0.1 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.1 GO:0003407 neural retina development(GO:0003407)
0.1 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 2.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.3 GO:0001554 luteolysis(GO:0001554)
0.1 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.9 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.1 0.4 GO:0060789 hair follicle placode formation(GO:0060789)
0.1 1.4 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 1.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 2.6 GO:0048477 oogenesis(GO:0048477)
0.0 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 1.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 2.0 GO:0009408 response to heat(GO:0009408)
0.0 0.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.6 GO:0048568 embryonic organ development(GO:0048568)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 3.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.6 GO:0044804 nucleophagy(GO:0044804)
0.0 4.9 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.2 GO:2001023 regulation of response to drug(GO:2001023)
0.0 1.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.2 GO:0007595 lactation(GO:0007595)
0.0 0.6 GO:0007616 long-term memory(GO:0007616)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 1.9 GO:0042100 B cell proliferation(GO:0042100)
0.0 2.2 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 3.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 1.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 1.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.6 GO:0042108 positive regulation of cytokine biosynthetic process(GO:0042108)
0.0 1.2 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.5 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.9 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.9 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.7 GO:0051437 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.0 0.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.0 GO:0061196 branch elongation involved in ureteric bud branching(GO:0060681) fungiform papilla development(GO:0061196) negative regulation of mesonephros development(GO:0061218) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) regulation of branch elongation involved in ureteric bud branching(GO:0072095) ureter development(GO:0072189) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 2.7 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.6 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:1901652 response to peptide(GO:1901652)
0.0 0.5 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.6 GO:0097179 protease inhibitor complex(GO:0097179)
1.9 7.6 GO:0097224 sperm connecting piece(GO:0097224)
1.7 36.1 GO:0042613 MHC class II protein complex(GO:0042613)
1.6 6.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
1.5 10.2 GO:0032584 growth cone membrane(GO:0032584)
1.3 3.9 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.2 3.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.2 8.3 GO:0036021 endolysosome lumen(GO:0036021)
1.1 22.6 GO:0001891 phagocytic cup(GO:0001891)
1.0 5.1 GO:0005602 complement component C1 complex(GO:0005602)
1.0 4.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.9 15.1 GO:0097512 cardiac myofibril(GO:0097512)
0.9 14.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.9 10.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.9 6.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.8 3.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.8 4.8 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 23.6 GO:0035371 microtubule plus-end(GO:0035371)
0.7 3.6 GO:0089701 U2AF(GO:0089701)
0.7 9.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.7 9.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.7 5.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 4.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6 9.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 19.0 GO:0042101 T cell receptor complex(GO:0042101)
0.6 10.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.6 8.1 GO:0005833 hemoglobin complex(GO:0005833)
0.6 2.3 GO:0097449 astrocyte projection(GO:0097449)
0.6 6.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 1.7 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.6 9.6 GO:0033270 paranode region of axon(GO:0033270)
0.6 7.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 3.9 GO:1990635 proximal dendrite(GO:1990635)
0.5 1.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 8.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.5 2.4 GO:0071546 pi-body(GO:0071546)
0.4 3.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 2.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 3.7 GO:0016013 syntrophin complex(GO:0016013)
0.4 19.5 GO:0001772 immunological synapse(GO:0001772)
0.4 2.8 GO:0014802 terminal cisterna(GO:0014802)
0.4 6.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 6.3 GO:0043194 axon initial segment(GO:0043194)
0.4 3.1 GO:0045180 basal cortex(GO:0045180)
0.4 2.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 1.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.3 10.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 1.4 GO:1990246 uniplex complex(GO:1990246)
0.3 13.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 0.6 GO:0043159 acrosomal matrix(GO:0043159)
0.3 13.6 GO:0048786 presynaptic active zone(GO:0048786)
0.3 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.3 4.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 1.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.3 12.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 3.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 2.2 GO:0034399 nuclear periphery(GO:0034399)
0.2 5.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 2.5 GO:0030008 TRAPP complex(GO:0030008)
0.2 9.7 GO:0043596 nuclear replication fork(GO:0043596)
0.2 3.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 2.1 GO:0071953 elastic fiber(GO:0071953)
0.2 0.6 GO:0097342 ripoptosome(GO:0097342)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.2 4.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.2 3.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 2.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 37.8 GO:0043209 myelin sheath(GO:0043209)
0.2 10.3 GO:0031201 SNARE complex(GO:0031201)
0.2 2.4 GO:0031045 dense core granule(GO:0031045)
0.2 0.9 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.3 GO:0000125 PCAF complex(GO:0000125)
0.1 50.8 GO:0045121 membrane raft(GO:0045121)
0.1 2.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 7.1 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 14.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 6.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.9 GO:0016235 aggresome(GO:0016235)
0.1 4.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 5.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 23.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 5.3 GO:0043235 receptor complex(GO:0043235)
0.1 3.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 3.7 GO:0031904 endosome lumen(GO:0031904)
0.1 9.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.3 GO:0071437 invadopodium(GO:0071437)
0.1 3.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 10.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 4.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 23.6 GO:0005635 nuclear envelope(GO:0005635)
0.1 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0060198 clathrin-sculpted vesicle(GO:0060198) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 5.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 4.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 1.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 46.3 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 2.2 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 21.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 3.7 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
2.8 11.3 GO:0019770 IgG receptor activity(GO:0019770)
2.4 7.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.2 13.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.1 6.4 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
2.0 5.9 GO:0005174 CD40 receptor binding(GO:0005174)
1.9 5.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.8 100.7 GO:0017080 sodium channel regulator activity(GO:0017080)
1.7 6.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.6 8.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.6 6.3 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
1.5 7.6 GO:0004995 tachykinin receptor activity(GO:0004995)
1.4 6.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.3 5.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.2 3.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.2 38.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
1.2 3.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.2 6.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.2 3.7 GO:0005148 prolactin receptor binding(GO:0005148)
1.2 3.7 GO:0032767 copper-dependent protein binding(GO:0032767)
1.2 6.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.2 8.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 9.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 4.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.1 3.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.1 3.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.1 8.6 GO:0004064 arylesterase activity(GO:0004064)
1.0 10.1 GO:0036310 annealing helicase activity(GO:0036310)
1.0 9.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 16.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.9 8.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.8 5.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.8 2.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.8 11.1 GO:0050700 CARD domain binding(GO:0050700)
0.7 2.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.7 7.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.7 2.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.7 14.5 GO:0051787 misfolded protein binding(GO:0051787)
0.7 3.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.7 2.1 GO:0005549 odorant binding(GO:0005549)
0.7 2.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.7 3.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.7 2.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.6 18.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.6 14.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.6 7.6 GO:0032027 myosin light chain binding(GO:0032027)
0.6 8.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 1.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6 9.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.6 2.4 GO:0015265 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.6 2.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.6 4.6 GO:0034711 inhibin binding(GO:0034711)
0.6 5.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 7.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 110.6 GO:0003823 antigen binding(GO:0003823)
0.5 3.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.5 8.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.5 3.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.5 14.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 2.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 3.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 14.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 6.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.4 1.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 8.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 19.4 GO:0070888 E-box binding(GO:0070888)
0.4 2.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4 8.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.4 1.2 GO:0032093 SAM domain binding(GO:0032093)
0.4 1.6 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.4 2.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.4 3.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 12.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 2.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 2.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.4 8.4 GO:0001968 fibronectin binding(GO:0001968)
0.4 2.2 GO:0039552 RIG-I binding(GO:0039552)
0.4 1.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.4 1.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.3 6.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 1.0 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.3 1.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 6.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 9.3 GO:0005521 lamin binding(GO:0005521)
0.3 1.7 GO:0002046 opsin binding(GO:0002046)
0.3 0.3 GO:0008094 DNA helicase activity(GO:0003678) DNA-dependent ATPase activity(GO:0008094)
0.3 5.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 1.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 10.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 3.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 3.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 2.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.3 1.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.3 1.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 2.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.4 GO:0043422 protein kinase B binding(GO:0043422)
0.3 5.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 20.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 1.9 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.3 6.3 GO:0002162 dystroglycan binding(GO:0002162)
0.3 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 7.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 6.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 0.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 5.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.2 0.7 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 0.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 87.8 GO:0030695 GTPase regulator activity(GO:0030695)
0.2 11.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 10.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 3.4 GO:0005522 profilin binding(GO:0005522)
0.2 1.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 0.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 2.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.2 7.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2 2.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.6 GO:0070697 activin receptor binding(GO:0070697)
0.2 0.8 GO:0004803 transposase activity(GO:0004803)
0.2 1.9 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 2.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 43.5 GO:0051015 actin filament binding(GO:0051015)
0.2 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.8 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.2 1.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 4.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 3.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 1.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 0.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 4.6 GO:0042287 MHC protein binding(GO:0042287)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 3.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 2.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 3.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.0 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 4.4 GO:0030507 spectrin binding(GO:0030507)
0.1 2.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 12.6 GO:0003774 motor activity(GO:0003774)
0.1 3.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 3.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.3 GO:0071949 FAD binding(GO:0071949)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 2.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 2.9 GO:0005109 frizzled binding(GO:0005109)
0.1 1.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 6.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 13.9 GO:0008017 microtubule binding(GO:0008017)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 3.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 20.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.7 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.1 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 7.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0019841 retinol binding(GO:0019841)
0.1 0.9 GO:0008201 heparin binding(GO:0008201)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.2 GO:0030246 carbohydrate binding(GO:0030246)
0.1 11.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 3.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 2.7 GO:0005178 integrin binding(GO:0005178)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.2 GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups(GO:0016747)
0.1 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 1.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 3.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 3.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 1.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 2.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.5 12.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 19.5 PID CD40 PATHWAY CD40/CD40L signaling
0.3 13.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 10.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 3.3 ST STAT3 PATHWAY STAT3 Pathway
0.3 22.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3 7.1 PID ARF 3PATHWAY Arf1 pathway
0.3 14.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 18.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 12.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 15.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 2.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 4.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 3.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 4.8 PID IL3 PATHWAY IL3-mediated signaling events
0.2 6.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 4.0 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 3.9 PID IL23 PATHWAY IL23-mediated signaling events
0.2 4.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 14.6 PID CMYB PATHWAY C-MYB transcription factor network
0.1 11.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 15.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 6.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 1.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 1.5 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.9 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 1.0 PID MYC PATHWAY C-MYC pathway
0.1 1.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 25.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 15.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 14.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.8 8.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.7 14.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.6 6.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 11.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 8.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.6 2.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6 10.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 13.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 23.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.5 1.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.4 77.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 7.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 19.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 5.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 6.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 20.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 9.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 11.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 10.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 6.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 6.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 3.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3 34.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.3 8.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 4.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 2.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 3.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 6.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 6.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.2 6.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 3.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 8.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 6.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 2.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 23.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 9.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 8.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 2.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 9.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 11.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 5.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 5.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 6.6 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 8.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 3.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 1.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases