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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MLXIPL

Z-value: 0.45

Motif logo

Transcription factors associated with MLXIPL

Gene Symbol Gene ID Gene Info
ENSG00000009950.11 MLX interacting protein like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MLXIPLhg19_v2_chr7_-_73038867_73038878,
hg19_v2_chr7_-_73038822_73038862
0.452.1e-12Click!

Activity profile of MLXIPL motif

Sorted Z-values of MLXIPL motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_226658 42.76 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr5_+_134240588 26.35 ENST00000254908.6
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr16_-_30032610 24.53 ENST00000574405.1
double C2-like domains, alpha
chr1_+_233086326 24.05 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr16_+_66914264 21.49 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_+_222846 20.80 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr19_-_12721616 20.22 ENST00000311437.6
zinc finger protein 490
chr19_+_58095501 19.54 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
zinc finger protein interacting with K protein 1
chr16_+_4784458 19.13 ENST00000590191.1
chromosome 16 open reading frame 71
chr14_+_102027688 18.95 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr22_+_24891210 18.77 ENST00000382760.2
ureidopropionase, beta
chr19_-_11669960 17.62 ENST00000589171.1
ENST00000590700.1
ENST00000586683.1
ENST00000593077.1
ENST00000252445.3
elongation factor 1 homolog (S. cerevisiae)
chr4_+_175204818 17.33 ENST00000503780.1
centrosomal protein 44kDa
chr14_-_106209368 17.18 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_-_45559642 17.05 ENST00000426282.2
CTA-217C2.1
chr6_-_74161977 16.87 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr15_-_77712477 16.58 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr22_+_23248512 16.55 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr11_-_64511789 16.39 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_-_106092403 16.35 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr14_+_75745477 16.10 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr19_-_12662240 15.93 ENST00000416136.1
ENST00000428311.1
zinc finger protein 564
ZNF709
chr18_+_21693306 15.88 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr22_+_23243156 15.30 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr14_-_106174960 15.23 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr5_+_175792459 14.95 ENST00000310389.5
ADP-ribosylation factor-like 10
chr6_+_33043703 14.95 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr6_+_31865552 14.94 ENST00000469372.1
ENST00000497706.1
complement component 2
chr19_-_39826639 14.79 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr21_-_46330545 14.73 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr10_-_99393242 14.50 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chr18_+_71815743 14.29 ENST00000169551.6
ENST00000580087.1
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr11_-_85565906 14.12 ENST00000544076.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr18_-_21017817 13.59 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
transmembrane protein 241
chr12_+_130554803 13.56 ENST00000535487.1
RP11-474D1.2
chr17_+_38083977 13.51 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr11_-_61129335 13.48 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
cytochrome b561 family, member A3
chr3_-_53080047 13.43 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
Scm-like with four mbt domains 1
chr10_-_99393208 13.36 ENST00000307450.6
MORN repeat containing 4
chr1_+_46668994 12.98 ENST00000371980.3
leucine rich adaptor protein 1
chr4_-_84406218 12.94 ENST00000515303.1
family with sequence similarity 175, member A
chr22_+_23040274 12.11 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr14_-_106054659 12.04 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr15_+_90777424 11.94 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr2_+_95691445 11.88 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
mal, T-cell differentiation protein
chr14_+_73704201 11.79 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
papilin, proteoglycan-like sulfated glycoprotein
chr16_+_4784273 11.67 ENST00000299320.5
ENST00000586724.1
chromosome 16 open reading frame 71
chr12_-_133050726 11.64 ENST00000595994.1
mucin 8
chr1_-_38157877 11.61 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr12_-_133707021 11.50 ENST00000537226.1
zinc finger protein 891
chr7_+_149597 11.37 ENST00000484550.1
ENST00000479592.1
ENST00000471299.1
AC093627.10
chr9_+_140513438 11.28 ENST00000462484.1
ENST00000334856.6
ENST00000460843.1
euchromatic histone-lysine N-methyltransferase 1
chr11_+_1874200 11.25 ENST00000311604.3
lymphocyte-specific protein 1
chr22_+_23264766 11.22 ENST00000390331.2
immunoglobulin lambda constant 7
chr19_+_2977444 11.07 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chrX_-_153881842 10.43 ENST00000369585.3
ENST00000247306.4
cancer/testis antigen 2
chr2_+_111490161 10.39 ENST00000340561.4
acyl-CoA oxidase-like
chr3_+_127634312 10.25 ENST00000407609.3
kelch repeat and BTB (POZ) domain containing 12
chr2_+_95691417 10.24 ENST00000309988.4
mal, T-cell differentiation protein
chr11_+_62439126 10.19 ENST00000377953.3
chromosome 11 open reading frame 83
chr4_+_75023816 10.14 ENST00000395759.2
ENST00000331145.6
ENST00000359107.5
ENST00000325278.6
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr10_+_49514698 9.97 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr1_+_52870227 9.81 ENST00000257181.9
pre-mRNA processing factor 38A
chr4_-_153601136 9.80 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr9_-_95432536 9.75 ENST00000287996.3
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr6_+_56954867 9.68 ENST00000370708.4
ENST00000370702.1
zinc finger protein 451
chr19_-_36822595 9.63 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
long intergenic non-protein coding RNA 665
chr19_+_19144384 9.60 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr7_-_40174201 9.54 ENST00000306984.6
M-phase specific PLK1 interacting protein
chr3_+_9851632 9.52 ENST00000426895.4
tubulin tyrosine ligase-like family, member 3
chr10_-_120514720 9.51 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr17_-_42402138 9.50 ENST00000592857.1
ENST00000586016.1
ENST00000590194.1
ENST00000377095.5
ENST00000588049.1
ENST00000586633.1
ENST00000537904.2
ENST00000585636.1
ENST00000585523.1
ENST00000225308.8
solute carrier family 25, member 39
chr14_-_106237742 9.49 ENST00000390551.2
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_89545079 9.45 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr4_+_139936905 9.43 ENST00000280614.2
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr7_+_50344289 9.39 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKAROS family zinc finger 1 (Ikaros)
chr19_-_18508396 9.32 ENST00000595840.1
ENST00000339007.3
leucine rich repeat containing 25
chr11_+_695787 9.31 ENST00000526170.1
ENST00000488769.1
transmembrane protein 80
chr1_-_40237020 9.29 ENST00000327582.5
3-oxoacid CoA transferase 2
chr17_-_15244894 9.22 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr19_-_5340730 9.20 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr19_-_53289995 9.18 ENST00000338230.3
zinc finger protein 600
chr20_+_42839600 9.12 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr19_-_39523165 9.12 ENST00000509137.2
ENST00000292853.4
F-box protein 27
chr22_-_21482352 9.01 ENST00000329949.3
POM121 transmembrane nucleoporin-like 7
chr8_+_142402089 8.97 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr19_+_41509851 8.82 ENST00000593831.1
ENST00000330446.5
cytochrome P450, family 2, subfamily B, polypeptide 6
chr19_-_7968427 8.82 ENST00000539278.1
Uncharacterized protein
chr20_+_42839722 8.82 ENST00000442383.1
ENST00000435163.1
OSER1 antisense RNA 1 (head to head)
chr20_+_55904815 8.80 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11 meiotic protein covalently bound to DSB
chr19_+_840963 8.75 ENST00000234347.5
proteinase 3
chr16_+_58283814 8.66 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chrX_+_16737718 8.61 ENST00000380155.3
synapse associated protein 1
chr16_+_19729586 8.60 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr11_-_64512469 8.54 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_+_2794750 8.51 ENST00000452765.2
ENST00000389838.2
SH3-domain binding protein 2
chr9_-_139094988 8.41 ENST00000371746.3
LIM homeobox 3
chr3_+_182511266 8.27 ENST00000323116.5
ENST00000493826.1
ATPase, class VI, type 11B
chr1_-_15850676 8.23 ENST00000440484.1
ENST00000333868.5
caspase 9, apoptosis-related cysteine peptidase
chr22_+_22786288 8.20 ENST00000390301.2
immunoglobulin lambda variable 1-36
chr4_+_7045042 8.16 ENST00000310074.7
ENST00000512388.1
transcriptional adaptor 2B
chr19_-_54872556 8.07 ENST00000444687.1
leukocyte-associated immunoglobulin-like receptor 1
chr14_-_81687197 8.07 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr16_+_1306060 8.06 ENST00000397534.2
tryptase delta 1
chr5_-_132166579 8.05 ENST00000378679.3
shroom family member 1
chr19_-_57183114 8.03 ENST00000537055.2
ENST00000601659.1
zinc finger protein 835
chr15_+_51200871 8.02 ENST00000560508.1
adaptor-related protein complex 4, epsilon 1 subunit
chr1_-_113498616 7.99 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr12_+_113376249 7.98 ENST00000551007.1
ENST00000548514.1
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_52133588 7.95 ENST00000570106.2
sialic acid binding Ig-like lectin 5
chr2_-_220083671 7.92 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_10217364 7.90 ENST00000430370.1
peter pan homolog (Drosophila)
chr16_-_4292071 7.90 ENST00000399609.3
sarcalumenin
chr21_+_46494466 7.84 ENST00000539173.1
ENST00000389863.4
ENST00000348831.4
ENST00000437626.1
adenosine deaminase, RNA-specific, B1
chr4_-_89205879 7.84 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr14_+_57857262 7.83 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr22_+_20104947 7.78 ENST00000402752.1
RAN binding protein 1
chr19_+_1067492 7.76 ENST00000586866.1
histocompatibility (minor) HA-1
chr7_+_72742178 7.75 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr2_+_29338236 7.66 ENST00000320081.5
CAP-GLY domain containing linker protein family, member 4
chr16_-_30546141 7.64 ENST00000535210.1
ENST00000395094.3
zinc finger protein 747
chr14_+_24641062 7.63 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8 meiotic recombination protein
chr15_-_79103757 7.62 ENST00000388820.4
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr16_-_88729473 7.59 ENST00000301012.3
ENST00000569177.1
mevalonate (diphospho) decarboxylase
chr1_+_9005917 7.58 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
carbonic anhydrase VI
chr15_-_52404921 7.55 ENST00000561198.1
ENST00000260442.3
BCL2-like 10 (apoptosis facilitator)
chr19_+_12721725 7.54 ENST00000446165.1
ENST00000343325.4
ENST00000458122.3
zinc finger protein 791
chr19_+_1205740 7.53 ENST00000326873.7
serine/threonine kinase 11
chr10_+_74451883 7.47 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr19_+_1067144 7.45 ENST00000313093.2
histocompatibility (minor) HA-1
chr12_+_30948865 7.42 ENST00000547804.1
long intergenic non-protein coding RNA 941
chr16_+_640201 7.41 ENST00000563109.1
RAB40C, member RAS oncogene family
chr16_-_5115913 7.40 ENST00000474471.3
chromosome 16 open reading frame 89
chr6_+_7108210 7.39 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr22_+_45725524 7.38 ENST00000405548.3
family with sequence similarity 118, member A
chr12_-_42631529 7.38 ENST00000548917.1
YY1 associated factor 2
chr2_-_220083692 7.36 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_10217270 7.34 ENST00000446223.1
peter pan homolog (Drosophila)
chr8_-_99306564 7.30 ENST00000430223.2
NIPA-like domain containing 2
chr12_+_130822417 7.29 ENST00000245255.3
piwi-like RNA-mediated gene silencing 1
chr3_+_10068095 7.29 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr2_-_136875712 7.28 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr17_-_76778339 7.24 ENST00000591455.1
ENST00000446868.3
ENST00000361101.4
ENST00000589296.1
cytohesin 1
chr11_-_18034701 7.21 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr7_+_72742162 7.21 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr11_+_1891380 7.20 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr3_-_167813672 7.16 ENST00000470487.1
golgi integral membrane protein 4
chr12_+_58013693 7.13 ENST00000320442.4
ENST00000379218.2
solute carrier family 26, member 10
chr3_+_32726774 7.12 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr5_-_131826457 7.07 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr19_-_53466095 7.04 ENST00000391786.2
ENST00000434371.2
ENST00000357666.4
ENST00000438970.2
ENST00000270457.4
ENST00000535506.1
ENST00000444460.2
ENST00000457013.2
zinc finger protein 816
chr1_-_212588157 7.01 ENST00000261455.4
ENST00000535273.1
transmembrane protein 206
chr19_+_42381337 7.00 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr3_-_167813132 6.99 ENST00000309027.4
golgi integral membrane protein 4
chr7_-_99149715 6.93 ENST00000449309.1
family with sequence similarity 200, member A
chr1_+_161494036 6.92 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chr2_+_89975669 6.88 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr9_-_86571628 6.88 ENST00000376344.3
chromosome 9 open reading frame 64
chr16_-_31454346 6.87 ENST00000564218.1
ENST00000315678.5
zinc finger protein 843
chr6_+_139456226 6.87 ENST00000367658.2
headcase homolog (Drosophila)
chr6_-_159420780 6.83 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chrX_+_1710484 6.82 ENST00000313871.3
ENST00000381261.3
A kinase (PRKA) anchor protein 17A
chr11_-_1036706 6.80 ENST00000421673.2
mucin 6, oligomeric mucus/gel-forming
chrX_+_11776410 6.79 ENST00000361672.2
male-specific lethal 3 homolog (Drosophila)
chr16_-_1525016 6.76 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chr4_+_667686 6.73 ENST00000505477.1
myosin, light chain 5, regulatory
chr3_-_128712955 6.73 ENST00000265068.5
KIAA1257
chr1_-_67390474 6.70 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WD repeat domain 78
chr12_-_51718436 6.70 ENST00000544402.1
bridging integrator 2
chr11_-_64511575 6.65 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_18656028 6.62 ENST00000336349.5
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr2_-_197036289 6.60 ENST00000263955.4
serine/threonine kinase 17b
chr10_+_15139330 6.57 ENST00000378202.5
ENST00000378197.4
ribonuclease P/MRP 38kDa subunit
chr12_-_122751002 6.56 ENST00000267199.4
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr10_-_104001231 6.56 ENST00000370002.3
paired-like homeodomain 3
chr1_-_40254482 6.49 ENST00000397360.2
ENST00000372827.3
bone morphogenetic protein 8b
chr3_+_16926441 6.45 ENST00000418129.2
ENST00000396755.2
phospholipase C-like 2
chr6_-_159421198 6.44 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
radial spoke 3 homolog (Chlamydomonas)
chr11_+_118175132 6.43 ENST00000361763.4
CD3e molecule, epsilon (CD3-TCR complex)
chr3_+_49977490 6.43 ENST00000539992.1
RNA binding motif protein 6
chr17_+_18163848 6.43 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
mitochondrial elongation factor 2
chr20_+_1206679 6.41 ENST00000402452.1
ENST00000409241.1
ENST00000381882.2
ENST00000246108.3
RAD21-like 1 (S. pombe)
chr1_-_16678914 6.40 ENST00000375592.3
F-box protein 42
chr5_-_131347583 6.38 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr2_+_233925064 6.36 ENST00000359570.5
ENST00000538935.1
inositol polyphosphate-5-phosphatase, 145kDa
chr15_+_51200859 6.35 ENST00000261842.5
adaptor-related protein complex 4, epsilon 1 subunit
chr1_+_3569129 6.35 ENST00000354437.4
ENST00000357733.3
ENST00000346387.4
tumor protein p73
chr21_-_46348694 6.35 ENST00000355153.4
ENST00000397850.2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_3599492 6.34 ENST00000435558.1
ENST00000345901.3
purinergic receptor P2X, ligand-gated ion channel, 5
chrX_+_153813407 6.33 ENST00000443287.2
ENST00000333128.3
cancer/testis antigen 1A
chr3_+_49977523 6.33 ENST00000422955.1
RNA binding motif protein 6
chr22_+_40390930 6.32 ENST00000333407.6
family with sequence similarity 83, member F
chr3_+_49977440 6.32 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RNA binding motif protein 6
chr11_+_118215036 6.31 ENST00000392883.2
ENST00000532917.1
CD3g molecule, gamma (CD3-TCR complex)
chr18_+_39766626 6.30 ENST00000593234.1
ENST00000585627.1
ENST00000591199.1
ENST00000586990.1
ENST00000593051.1
ENST00000593316.1
ENST00000591381.1
ENST00000585639.1
ENST00000589068.1
long intergenic non-protein coding RNA 907
chr7_+_102715315 6.29 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
armadillo repeat containing 10
chr22_+_23229960 6.21 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr21_-_45660840 6.19 ENST00000400377.3
inducible T-cell co-stimulator ligand
chr7_+_149535455 6.19 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chrY_-_16098393 6.15 ENST00000250825.4
variable charge, Y-linked

Network of associatons between targets according to the STRING database.

First level regulatory network of MLXIPL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 18.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
5.4 5.4 GO:0008355 olfactory learning(GO:0008355)
4.7 14.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
4.6 13.8 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
4.5 13.6 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
3.8 15.2 GO:0018094 protein polyglycylation(GO:0018094)
3.7 3.7 GO:0002688 regulation of leukocyte chemotaxis(GO:0002688)
3.6 3.6 GO:0046425 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
3.6 3.6 GO:0036035 osteoclast development(GO:0036035)
3.4 10.3 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
3.3 10.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
3.1 12.5 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
3.1 9.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
3.1 9.2 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.9 8.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
2.9 26.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
2.9 28.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.9 42.8 GO:0015671 oxygen transport(GO:0015671)
2.8 8.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
2.8 8.5 GO:0097359 UDP-glucosylation(GO:0097359)
2.8 11.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
2.8 22.3 GO:0034587 piRNA metabolic process(GO:0034587)
2.8 8.3 GO:0100009 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
2.7 16.0 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.6 7.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.5 15.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.5 7.5 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
2.5 7.4 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
2.5 9.8 GO:0032053 ciliary basal body organization(GO:0032053)
2.3 9.3 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
2.2 11.2 GO:0015670 carbon dioxide transport(GO:0015670)
2.2 6.6 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
2.2 22.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
2.2 6.6 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
2.1 6.4 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.1 15.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
2.1 17.1 GO:0001661 conditioned taste aversion(GO:0001661)
2.1 6.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.1 14.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
2.1 6.3 GO:0050870 positive regulation of T cell activation(GO:0050870)
2.1 4.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
2.1 14.7 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
2.1 6.3 GO:0002125 maternal aggressive behavior(GO:0002125)
2.1 10.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.1 12.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
2.1 8.3 GO:0015917 aminophospholipid transport(GO:0015917)
2.0 6.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.0 6.0 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
2.0 7.8 GO:0006382 adenosine to inosine editing(GO:0006382)
2.0 5.9 GO:2000410 regulation of thymocyte migration(GO:2000410)
1.9 15.5 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
1.9 5.7 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.9 5.7 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.9 7.5 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
1.8 7.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.8 7.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.8 30.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.8 14.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.8 5.3 GO:0090155 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
1.7 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
1.7 13.7 GO:0015693 magnesium ion transport(GO:0015693)
1.7 18.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.7 21.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.7 16.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.6 11.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.6 107.7 GO:0006910 phagocytosis, recognition(GO:0006910)
1.6 4.8 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
1.6 17.6 GO:0015886 heme transport(GO:0015886)
1.6 6.4 GO:2000416 regulation of eosinophil migration(GO:2000416)
1.6 12.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
1.6 26.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.6 3.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.5 7.6 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
1.5 1.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
1.5 4.4 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
1.4 4.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.4 2.9 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.4 1.4 GO:0015808 L-alanine transport(GO:0015808)
1.4 1.4 GO:0045402 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
1.4 4.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
1.4 2.8 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.4 4.2 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
1.4 4.2 GO:1990641 response to iron ion starvation(GO:1990641)
1.4 6.9 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.4 5.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
1.4 1.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.3 4.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.3 9.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
1.3 6.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
1.3 6.5 GO:0015824 proline transport(GO:0015824)
1.3 5.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
1.3 6.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.3 6.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.3 5.1 GO:0003095 pressure natriuresis(GO:0003095)
1.3 10.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
1.3 7.6 GO:0015811 L-cystine transport(GO:0015811)
1.3 8.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.3 3.8 GO:0055073 cadmium ion homeostasis(GO:0055073)
1.3 5.0 GO:0044375 regulation of peroxisome size(GO:0044375)
1.2 7.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.2 3.7 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
1.2 3.7 GO:0031627 telomeric loop formation(GO:0031627)
1.2 7.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.2 3.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.2 4.8 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
1.2 3.6 GO:0051684 maintenance of Golgi location(GO:0051684)
1.2 7.1 GO:0018095 protein polyglutamylation(GO:0018095)
1.2 7.1 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
1.2 5.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.2 1.2 GO:0019249 lactate biosynthetic process(GO:0019249)
1.2 8.2 GO:0019532 oxalate transport(GO:0019532)
1.2 14.0 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
1.2 1.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
1.2 5.8 GO:0035063 nuclear speck organization(GO:0035063)
1.2 13.8 GO:0006776 vitamin A metabolic process(GO:0006776)
1.2 4.6 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.1 10.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
1.1 20.0 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
1.1 5.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.1 3.3 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
1.1 6.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.1 19.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
1.1 3.3 GO:0003285 septum secundum development(GO:0003285)
1.1 1.1 GO:0048859 formation of anatomical boundary(GO:0048859)
1.1 1.1 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
1.1 7.5 GO:0008218 bioluminescence(GO:0008218)
1.1 1.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
1.1 3.2 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.1 4.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
1.1 14.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 3.1 GO:0010165 response to X-ray(GO:0010165)
1.0 4.1 GO:0010936 positive regulation of tolerance induction(GO:0002645) negative regulation of macrophage cytokine production(GO:0010936)
1.0 3.0 GO:1905075 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
1.0 5.1 GO:0007288 sperm axoneme assembly(GO:0007288)
1.0 3.0 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.0 6.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
1.0 2.0 GO:0001575 globoside metabolic process(GO:0001575)
1.0 3.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
1.0 3.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
1.0 3.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
1.0 3.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.0 8.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
1.0 11.8 GO:0055089 fatty acid homeostasis(GO:0055089)
1.0 2.0 GO:0032328 alanine transport(GO:0032328)
1.0 4.9 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.0 3.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
1.0 15.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
1.0 2.9 GO:0060084 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) synaptic transmission involved in micturition(GO:0060084)
1.0 14.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.0 3.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
1.0 1.9 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.0 4.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.0 2.9 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.9 2.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.9 2.8 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.9 4.7 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.9 11.2 GO:0032025 response to cobalt ion(GO:0032025)
0.9 7.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.9 5.6 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.9 4.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.9 37.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.9 18.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.9 5.3 GO:1901376 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.9 8.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.9 7.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.9 6.1 GO:0015705 iodide transport(GO:0015705)
0.9 6.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.9 2.6 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.8 3.4 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.8 10.9 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.8 1.7 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.8 4.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.8 6.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.8 3.3 GO:0080009 mRNA methylation(GO:0080009)
0.8 2.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.8 1.6 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.8 2.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.8 3.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.8 4.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.8 2.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.8 1.6 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.8 4.7 GO:0046208 spermine catabolic process(GO:0046208)
0.8 3.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.8 7.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.8 3.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.8 3.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.8 3.8 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.8 3.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.8 4.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.8 0.8 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.8 5.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.8 2.3 GO:0033212 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.8 3.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.8 6.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.8 7.5 GO:0009642 response to light intensity(GO:0009642)
0.7 3.7 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
0.7 1.5 GO:0046618 drug export(GO:0046618)
0.7 7.4 GO:0018209 peptidyl-serine modification(GO:0018209)
0.7 5.9 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.7 2.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.7 3.6 GO:0072313 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.7 2.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.7 9.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.7 3.6 GO:0061107 seminal vesicle development(GO:0061107)
0.7 1.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.7 6.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.7 2.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.7 4.1 GO:0030397 mitotic nuclear envelope disassembly(GO:0007077) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.7 2.7 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.7 0.7 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.7 61.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.7 4.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.7 3.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.7 2.7 GO:0097421 liver regeneration(GO:0097421)
0.7 6.0 GO:0044116 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116)
0.7 9.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.7 3.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 2.0 GO:0070781 response to biotin(GO:0070781)
0.7 1.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.7 2.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.7 2.0 GO:0035634 response to stilbenoid(GO:0035634)
0.6 7.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.6 1.9 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 1.9 GO:1990502 dense core granule maturation(GO:1990502)
0.6 1.9 GO:0002384 hepatic immune response(GO:0002384)
0.6 11.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.6 4.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.6 3.8 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.6 2.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.6 7.0 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.6 5.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.6 6.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.6 5.0 GO:0032790 ribosome disassembly(GO:0032790)
0.6 5.0 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.6 3.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.6 2.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.6 1.8 GO:0035564 regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.6 1.8 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.6 9.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 2.4 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.6 1.8 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.6 2.4 GO:0006956 complement activation(GO:0006956)
0.6 1.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 1.8 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.6 4.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.6 4.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.6 1.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.6 1.8 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.6 1.8 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.6 2.9 GO:0046968 peptide antigen transport(GO:0046968)
0.6 5.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.6 22.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.6 2.3 GO:0000103 sulfate assimilation(GO:0000103)
0.6 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6 2.9 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 2.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.6 2.3 GO:0072299 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.6 14.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.6 2.3 GO:1902159 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.6 5.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.6 2.3 GO:0035425 autocrine signaling(GO:0035425)
0.6 5.0 GO:0035865 cellular response to potassium ion(GO:0035865)
0.6 5.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.6 2.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.6 42.9 GO:0006968 cellular defense response(GO:0006968)
0.6 3.3 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.6 5.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.6 6.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.6 13.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.6 9.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.5 2.2 GO:0002215 defense response to nematode(GO:0002215)
0.5 2.2 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.5 2.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 2.7 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.5 16.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.5 1.6 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.5 1.6 GO:0034227 tRNA thio-modification(GO:0034227)
0.5 7.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.5 1.6 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.5 2.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.5 3.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.5 2.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.5 1.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.5 14.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.5 5.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.5 2.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.5 2.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 2.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 3.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.5 33.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.5 9.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.5 10.5 GO:0044458 motile cilium assembly(GO:0044458)
0.5 8.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 5.5 GO:0030334 regulation of cell migration(GO:0030334)
0.5 1.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5 1.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.5 1.5 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.5 1.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.5 1.9 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.5 1.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.5 1.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.5 6.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.5 2.4 GO:0016240 autophagosome docking(GO:0016240)
0.5 1.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.5 1.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.5 4.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.5 1.8 GO:0003335 corneocyte development(GO:0003335)
0.5 1.4 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.5 1.4 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.5 2.7 GO:0071105 response to interleukin-11(GO:0071105)
0.4 2.7 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.4 1.3 GO:0097049 motor neuron apoptotic process(GO:0097049)
0.4 3.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.4 10.0 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.4 2.6 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.4 2.2 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.4 5.6 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.4 0.9 GO:0071320 cellular response to cAMP(GO:0071320)
0.4 2.6 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.4 10.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.4 2.5 GO:1901563 response to camptothecin(GO:1901563)
0.4 2.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.3 GO:0052314 serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.4 4.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.4 7.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 3.7 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 2.0 GO:0050686 negative regulation of mRNA processing(GO:0050686)
0.4 2.8 GO:0018377 protein myristoylation(GO:0018377)
0.4 1.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4 2.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 7.6 GO:0002407 dendritic cell chemotaxis(GO:0002407)
0.4 2.4 GO:0035384 thioester biosynthetic process(GO:0035384) acyl-CoA biosynthetic process(GO:0071616)
0.4 2.8 GO:0042126 nitrate metabolic process(GO:0042126)
0.4 6.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 1.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 1.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.4 2.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.4 9.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 2.3 GO:0006196 AMP catabolic process(GO:0006196)
0.4 8.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4 1.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 2.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 1.2 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.4 9.2 GO:0006972 hyperosmotic response(GO:0006972)
0.4 2.3 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.4 4.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.4 2.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4 5.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.4 1.5 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.4 3.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 1.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.4 2.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 0.8 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.4 1.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099) somatostatin secretion(GO:0070253)
0.4 8.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 13.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.4 1.9 GO:0043589 skin morphogenesis(GO:0043589)
0.4 1.5 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.4 8.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.4 3.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4 5.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4 3.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.4 2.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 1.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 2.1 GO:0051321 meiotic cell cycle(GO:0051321)
0.4 5.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.4 2.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.4 2.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.4 1.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 12.7 GO:0032456 endocytic recycling(GO:0032456)
0.4 1.1 GO:0051182 coenzyme transport(GO:0051182)
0.4 2.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 0.7 GO:0042026 protein refolding(GO:0042026)
0.3 2.1 GO:0032570 response to progesterone(GO:0032570)
0.3 0.7 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.3 3.8 GO:0017085 response to insecticide(GO:0017085)
0.3 1.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 2.7 GO:0070995 NADPH oxidation(GO:0070995)
0.3 1.4 GO:0043632 ubiquitin-dependent protein catabolic process(GO:0006511) modification-dependent macromolecule catabolic process(GO:0043632)
0.3 2.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.3 3.7 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 5.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 0.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 6.7 GO:0003341 cilium movement(GO:0003341)
0.3 2.0 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.3 2.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 4.6 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.3 3.3 GO:0060326 cell chemotaxis(GO:0060326)
0.3 1.3 GO:0060214 stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.3 5.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.3 9.4 GO:0015695 organic cation transport(GO:0015695)
0.3 1.3 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.3 3.2 GO:0019627 urea cycle(GO:0000050) urea metabolic process(GO:0019627) nitrogen cycle metabolic process(GO:0071941)
0.3 2.6 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.3 2.5 GO:0015747 urate transport(GO:0015747)
0.3 2.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 3.1 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.3 5.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.3 5.3 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.3 6.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.5 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 0.3 GO:0060157 urinary bladder development(GO:0060157)
0.3 3.9 GO:0007512 adult heart development(GO:0007512)
0.3 12.4 GO:0019228 neuronal action potential(GO:0019228)
0.3 0.9 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.3 25.0 GO:0031295 T cell costimulation(GO:0031295)
0.3 1.5 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.3 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.3 2.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.3 1.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 4.6 GO:0021854 hypothalamus development(GO:0021854)
0.3 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 1.9 GO:0060841 venous blood vessel development(GO:0060841)
0.3 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 0.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 3.0 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3 4.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 1.3 GO:0001975 response to amphetamine(GO:0001975)
0.3 2.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 0.8 GO:0052047 positive regulation of fibrinolysis(GO:0051919) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.3 1.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.3 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.3 3.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 5.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 1.8 GO:0090110 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.3 1.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 1.3 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.3 2.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.3 6.3 GO:0042554 superoxide anion generation(GO:0042554)
0.3 1.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 3.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 2.2 GO:0045730 respiratory burst(GO:0045730)
0.2 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.0 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 4.4 GO:0019835 cytolysis(GO:0019835)
0.2 2.9 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.2 2.7 GO:0002021 response to dietary excess(GO:0002021)
0.2 1.2 GO:0015793 glycerol transport(GO:0015793)
0.2 5.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 1.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.5 GO:0023035 CD40 signaling pathway(GO:0023035)
0.2 1.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 4.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 1.9 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.2 2.8 GO:0001771 immunological synapse formation(GO:0001771)
0.2 1.6 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 0.7 GO:0015680 intracellular copper ion transport(GO:0015680)
0.2 3.2 GO:0007224 smoothened signaling pathway(GO:0007224)
0.2 0.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.2 1.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.2 0.4 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.2 2.4 GO:0006600 creatine metabolic process(GO:0006600)
0.2 1.5 GO:0019724 B cell mediated immunity(GO:0019724)
0.2 3.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 2.9 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.2 0.4 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.2 1.1 GO:0070166 enamel mineralization(GO:0070166)
0.2 3.4 GO:0006828 manganese ion transport(GO:0006828)
0.2 0.6 GO:0033078 extrathymic T cell differentiation(GO:0033078) extrathymic T cell selection(GO:0045062)
0.2 3.0 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.2 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.6 GO:0048733 sebaceous gland development(GO:0048733)
0.2 1.3 GO:0042116 macrophage activation(GO:0042116)
0.2 1.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 3.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 18.9 GO:0007286 spermatid development(GO:0007286)
0.2 1.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 4.1 GO:0097503 sialylation(GO:0097503)
0.2 0.6 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 0.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 0.6 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.2 0.8 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 1.8 GO:0015884 folic acid transport(GO:0015884)
0.2 2.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.2 2.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 1.0 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2 1.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 1.4 GO:0006449 regulation of translational termination(GO:0006449)
0.2 1.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 1.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 7.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 3.5 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604) regulation of keratinocyte differentiation(GO:0045616)
0.2 0.8 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.9 GO:0001696 gastric acid secretion(GO:0001696)
0.2 1.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.2 0.9 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 3.3 GO:0007140 male meiosis(GO:0007140)
0.2 5.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 0.9 GO:0008306 associative learning(GO:0008306)
0.2 5.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.9 GO:0010755 regulation of plasminogen activation(GO:0010755) negative regulation of plasminogen activation(GO:0010757)
0.2 0.7 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.2 1.8 GO:0015074 DNA integration(GO:0015074)
0.2 3.2 GO:0001502 cartilage condensation(GO:0001502)
0.2 3.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 3.6 GO:0071902 positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.2 1.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.2 1.1 GO:0015732 prostaglandin transport(GO:0015732)
0.2 1.6 GO:0006555 methionine metabolic process(GO:0006555)
0.2 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 2.1 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 5.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.2 0.5 GO:0007266 Rho protein signal transduction(GO:0007266)
0.2 5.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 12.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 2.0 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 3.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 0.7 GO:0032218 riboflavin transport(GO:0032218)
0.2 3.7 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.2 2.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 1.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 1.0 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.2 0.8 GO:0097090 presynaptic membrane organization(GO:0097090) presynaptic membrane assembly(GO:0097105)
0.2 3.0 GO:0097178 ruffle assembly(GO:0097178)
0.2 0.6 GO:0032571 response to vitamin K(GO:0032571)
0.2 7.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 2.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 1.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.2 4.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.2 1.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 8.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.9 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 2.8 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 1.0 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 4.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 3.0 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 4.7 GO:0010107 potassium ion import(GO:0010107)
0.1 2.5 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 1.0 GO:1902750 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.1 1.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 1.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0001694 histamine metabolic process(GO:0001692) histamine biosynthetic process(GO:0001694)
0.1 1.2 GO:0048511 rhythmic process(GO:0048511)
0.1 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 5.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 2.9 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.5 GO:1905225 thyroid-stimulating hormone signaling pathway(GO:0038194) cellular response to glycoprotein(GO:1904588) response to thyrotropin-releasing hormone(GO:1905225) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1 5.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.7 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.1 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 6.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.9 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 3.3 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 1.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.8 GO:0001554 luteolysis(GO:0001554)
0.1 6.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 1.3 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 1.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 7.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.6 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.1 2.0 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.4 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 14.8 GO:0007601 visual perception(GO:0007601)
0.1 2.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 1.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.4 GO:0033198 response to ATP(GO:0033198)
0.1 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.1 2.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 2.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 2.6 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.1 1.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 3.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 3.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 5.2 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.1 2.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.7 GO:0071800 podosome assembly(GO:0071800)
0.1 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) regulation of glucose mediated signaling pathway(GO:1902659)
0.1 0.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 2.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 5.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 2.8 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.1 1.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.8 GO:1901018 positive regulation of potassium ion transmembrane transporter activity(GO:1901018)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.3 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.1 0.2 GO:2001056 activation of cysteine-type endopeptidase activity(GO:0097202) positive regulation of cysteine-type endopeptidase activity(GO:2001056)
0.1 0.7 GO:0006284 base-excision repair(GO:0006284)
0.1 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 1.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.4 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 1.1 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.1 0.9 GO:0006751 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.2 GO:0006825 copper ion transport(GO:0006825)
0.1 1.7 GO:0090102 cochlea development(GO:0090102)
0.1 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.5 GO:0042220 response to cocaine(GO:0042220)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.1 0.6 GO:0035640 exploration behavior(GO:0035640)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.8 GO:0006544 glycine metabolic process(GO:0006544)
0.0 2.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 1.0 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.3 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.2 GO:0006298 mismatch repair(GO:0006298)
0.0 0.8 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 2.1 GO:1990266 neutrophil migration(GO:1990266)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.8 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 3.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.2 GO:0061081 positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 1.1 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.5 GO:0070873 regulation of glycogen metabolic process(GO:0070873)
0.0 0.2 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 2.7 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 3.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0071073 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.2 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 42.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
9.1 27.3 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
4.8 9.5 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
4.4 13.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
4.2 21.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
3.4 13.5 GO:0043293 apoptosome(GO:0043293)
3.1 12.4 GO:0030914 STAGA complex(GO:0030914)
2.6 10.5 GO:1990745 EARP complex(GO:1990745)
2.5 20.4 GO:0035976 AP1 complex(GO:0035976)
2.1 98.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.9 7.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.9 9.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.9 20.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.9 7.5 GO:1990246 uniplex complex(GO:1990246)
1.9 7.5 GO:0031417 NatC complex(GO:0031417)
1.8 22.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.8 5.4 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.8 7.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.6 8.2 GO:0036128 CatSper complex(GO:0036128)
1.5 7.5 GO:0036398 TCR signalosome(GO:0036398)
1.4 5.6 GO:0097361 CIA complex(GO:0097361)
1.4 5.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.4 1.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.4 1.4 GO:0030870 Mre11 complex(GO:0030870)
1.4 9.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.3 9.3 GO:0072487 MSL complex(GO:0072487)
1.2 3.6 GO:0097181 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.2 3.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.1 5.7 GO:0000801 central element(GO:0000801)
1.1 19.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.1 8.6 GO:0032010 phagolysosome(GO:0032010)
1.0 8.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.0 3.0 GO:0070382 exocytic vesicle(GO:0070382)
1.0 7.0 GO:0019815 B cell receptor complex(GO:0019815)
1.0 2.0 GO:0005652 nuclear lamina(GO:0005652)
1.0 16.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.0 3.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.9 8.5 GO:0016013 syntrophin complex(GO:0016013)
0.9 4.7 GO:0071797 LUBAC complex(GO:0071797)
0.9 4.5 GO:0045298 tubulin complex(GO:0045298)
0.9 4.5 GO:0089701 U2AF(GO:0089701)
0.9 10.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.8 8.5 GO:0070938 contractile ring(GO:0070938)
0.8 5.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8 5.8 GO:0001520 outer dense fiber(GO:0001520)
0.8 3.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.8 5.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.8 10.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.8 4.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.7 10.3 GO:0031045 dense core granule(GO:0031045)
0.7 2.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.7 2.9 GO:1990075 periciliary membrane compartment(GO:1990075)
0.7 14.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 4.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.7 9.9 GO:0030897 HOPS complex(GO:0030897)
0.7 4.2 GO:0043196 varicosity(GO:0043196)
0.7 3.4 GO:0070847 core mediator complex(GO:0070847)
0.7 12.1 GO:0042101 T cell receptor complex(GO:0042101)
0.7 7.3 GO:0033391 chromatoid body(GO:0033391)
0.7 13.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 2.6 GO:0097513 myosin II filament(GO:0097513)
0.7 8.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 2.6 GO:0031085 BLOC-3 complex(GO:0031085)
0.6 14.2 GO:0034451 centriolar satellite(GO:0034451)
0.6 10.9 GO:0005922 connexon complex(GO:0005922)
0.6 3.6 GO:1990037 Lewy body core(GO:1990037)
0.6 4.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.6 4.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.6 5.1 GO:0070652 HAUS complex(GO:0070652)
0.6 3.4 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 1.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.6 3.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 3.3 GO:0002177 manchette(GO:0002177)
0.6 2.2 GO:0016600 flotillin complex(GO:0016600)
0.5 13.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 2.7 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.5 12.9 GO:0000795 synaptonemal complex(GO:0000795)
0.5 2.6 GO:0005602 complement component C1 complex(GO:0005602)
0.5 9.8 GO:0044447 axoneme part(GO:0044447)
0.5 10.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.5 2.0 GO:0032279 asymmetric synapse(GO:0032279)
0.5 1.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 8.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.5 4.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.5 2.3 GO:0001652 granular component(GO:0001652)
0.5 2.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.5 3.7 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.5 3.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.5 6.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.5 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.5 18.9 GO:0016460 myosin II complex(GO:0016460)
0.4 4.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.4 1.8 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.4 1.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 2.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 6.3 GO:0001891 phagocytic cup(GO:0001891)
0.4 3.4 GO:0000322 storage vacuole(GO:0000322)
0.4 4.5 GO:0032797 SMN complex(GO:0032797)
0.4 2.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.4 28.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 11.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 0.8 GO:0044305 calyx of Held(GO:0044305)
0.4 5.1 GO:0035253 ciliary rootlet(GO:0035253)
0.4 2.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 4.2 GO:0097386 glial cell projection(GO:0097386)
0.4 3.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.4 6.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 28.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.4 4.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 1.5 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.4 4.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.4 20.5 GO:0005801 cis-Golgi network(GO:0005801)
0.4 3.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 2.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 1.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 3.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 3.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 3.3 GO:0042587 glycogen granule(GO:0042587)
0.3 2.0 GO:1990130 Iml1 complex(GO:1990130)
0.3 2.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 6.1 GO:0097225 sperm midpiece(GO:0097225)
0.3 1.9 GO:0034464 BBSome(GO:0034464)
0.3 1.8 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.3 49.5 GO:0072562 blood microparticle(GO:0072562)
0.3 12.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 1.5 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 1.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.3 3.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 2.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 2.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 1.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 12.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 27.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 2.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 5.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 5.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 2.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.9 GO:0016342 catenin complex(GO:0016342)
0.2 0.8 GO:0033263 CORVET complex(GO:0033263)
0.2 2.4 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 2.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 0.8 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.2 1.3 GO:0044294 dendritic growth cone(GO:0044294)
0.2 1.0 GO:0031905 early endosome lumen(GO:0031905)
0.2 25.6 GO:0032587 ruffle membrane(GO:0032587)
0.2 2.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 13.7 GO:0034707 chloride channel complex(GO:0034707)
0.2 6.0 GO:0009925 basal plasma membrane(GO:0009925)
0.2 4.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.2 4.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 5.2 GO:0005776 autophagosome(GO:0005776)
0.2 4.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 5.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 1.3 GO:0045179 apical cortex(GO:0045179)
0.2 0.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 17.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 7.3 GO:0005811 lipid particle(GO:0005811)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 14.5 GO:0031514 motile cilium(GO:0031514)
0.1 4.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 4.1 GO:0016459 myosin complex(GO:0016459)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 4.1 GO:0042629 mast cell granule(GO:0042629)
0.1 10.8 GO:0001726 ruffle(GO:0001726)
0.1 13.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.9 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 2.8 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 2.5 GO:0005902 microvillus(GO:0005902)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 11.4 GO:0043679 axon terminus(GO:0043679)
0.1 1.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 3.7 GO:0014704 intercalated disc(GO:0014704)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 6.5 GO:0042641 actomyosin(GO:0042641)
0.1 5.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.1 GO:0097443 sorting endosome(GO:0097443)
0.1 3.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 3.0 GO:0016235 aggresome(GO:0016235)
0.1 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 20.7 GO:0016324 apical plasma membrane(GO:0016324)
0.1 2.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 10.4 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.6 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 7.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.4 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.2 GO:0009986 cell surface(GO:0009986)
0.1 1.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 11.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0097223 sperm part(GO:0097223)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 15.2 GO:0016604 nuclear body(GO:0016604)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 28.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
6.6 26.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
6.1 18.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
4.6 13.8 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
4.5 13.6 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
4.2 12.5 GO:0032093 SAM domain binding(GO:0032093)
3.8 15.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
3.8 11.3 GO:0030350 iron-responsive element binding(GO:0030350)
3.6 21.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.4 24.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
3.3 10.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
3.3 42.8 GO:0005344 oxygen transporter activity(GO:0005344)
3.2 18.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
3.0 11.8 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
2.9 14.7 GO:0061665 SUMO ligase activity(GO:0061665)
2.9 8.8 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.8 8.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
2.6 7.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
2.5 7.6 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
2.4 7.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.4 7.3 GO:0034584 piRNA binding(GO:0034584)
2.4 131.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
2.3 11.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.2 9.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
2.1 38.5 GO:0019992 diacylglycerol binding(GO:0019992)
2.1 6.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
2.1 4.2 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
2.1 12.5 GO:0042577 lipid phosphatase activity(GO:0042577)
2.1 10.4 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
2.0 7.9 GO:0008410 CoA-transferase activity(GO:0008410)
2.0 7.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.9 9.5 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.9 15.0 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
1.8 14.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.8 22.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.8 5.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.8 5.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.8 5.3 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
1.7 5.2 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
1.7 5.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.6 12.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
1.6 4.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.6 4.7 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
1.5 19.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.5 11.8 GO:1990932 5.8S rRNA binding(GO:1990932)
1.5 13.3 GO:0003682 chromatin binding(GO:0003682)
1.4 4.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.4 2.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.4 12.9 GO:0004969 histamine receptor activity(GO:0004969)
1.4 4.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
1.4 4.2 GO:0004137 deoxycytidine kinase activity(GO:0004137)
1.4 4.2 GO:0019961 interferon binding(GO:0019961)
1.4 8.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.4 9.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.4 5.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.4 5.4 GO:0008422 beta-glucosidase activity(GO:0008422)
1.3 4.0 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
1.3 6.4 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.3 5.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.3 7.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
1.3 7.6 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
1.2 3.7 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.2 3.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
1.2 4.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.2 17.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
1.2 5.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.1 12.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
1.1 3.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
1.1 5.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.1 4.4 GO:0031716 calcitonin receptor binding(GO:0031716)
1.1 10.9 GO:0019826 oxygen sensor activity(GO:0019826)
1.1 3.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.1 10.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
1.1 3.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
1.1 4.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.1 3.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.1 14.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.0 13.6 GO:0042608 T cell receptor binding(GO:0042608)
1.0 3.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.0 6.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
1.0 3.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
1.0 3.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.0 3.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.0 13.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.0 2.0 GO:0009374 biotin binding(GO:0009374)
1.0 3.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.0 4.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.0 10.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.0 2.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
1.0 3.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
1.0 2.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 4.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.9 5.6 GO:0039552 RIG-I binding(GO:0039552)
0.9 10.3 GO:0004645 phosphorylase activity(GO:0004645)
0.9 2.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.9 2.7 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.9 1.8 GO:0016597 amino acid binding(GO:0016597) modified amino acid binding(GO:0072341)
0.9 3.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.9 4.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.9 2.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.9 3.5 GO:0017040 ceramidase activity(GO:0017040)
0.8 4.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.8 5.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.8 8.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.8 3.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.8 5.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.8 5.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.8 8.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.8 3.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.8 4.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8 3.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.8 8.7 GO:0031013 troponin I binding(GO:0031013)
0.8 4.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 4.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.8 8.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.8 2.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.8 5.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.7 3.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.7 3.7 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.7 4.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 3.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.7 1.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.7 12.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 5.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.7 2.2 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.7 4.4 GO:0004882 androgen receptor activity(GO:0004882)
0.7 36.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 3.6 GO:0031893 vasopressin receptor binding(GO:0031893)
0.7 2.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.7 2.9 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.7 21.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.7 5.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 2.8 GO:0008940 nitrate reductase activity(GO:0008940)
0.7 13.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.7 4.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 4.8 GO:0008142 oxysterol binding(GO:0008142)
0.7 7.5 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.7 4.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 6.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 2.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.7 12.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.7 5.9 GO:0043426 MRF binding(GO:0043426)
0.7 2.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 2.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.6 1.9 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.6 8.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.6 2.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.6 2.5 GO:0035473 lipase binding(GO:0035473)
0.6 4.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.6 1.9 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.6 1.9 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.6 3.7 GO:0051525 NFAT protein binding(GO:0051525)
0.6 4.3 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.6 4.9 GO:1990405 protein antigen binding(GO:1990405)
0.6 1.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 7.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.6 3.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.6 7.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6 7.7 GO:0070700 BMP receptor binding(GO:0070700)
0.6 4.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.6 1.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 7.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 2.9 GO:0070097 delta-catenin binding(GO:0070097)
0.6 7.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.6 6.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 9.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.6 3.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 1.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 2.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 3.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.5 3.7 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.5 6.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5 1.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 16.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.5 3.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 1.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5 2.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.5 9.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 5.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 7.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 10.6 GO:0050811 GABA receptor binding(GO:0050811)
0.5 4.0 GO:0001849 complement component C1q binding(GO:0001849)
0.5 2.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 10.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 2.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 2.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 17.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 1.4 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.5 9.5 GO:0051787 misfolded protein binding(GO:0051787)
0.5 1.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.5 19.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.5 1.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.5 11.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 2.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 2.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.5 2.3 GO:0070728 leucine binding(GO:0070728)
0.5 1.4 GO:0000035 acyl binding(GO:0000035)
0.5 2.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 5.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 13.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 4.5 GO:0005243 gap junction channel activity(GO:0005243)
0.4 9.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 34.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4 1.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 17.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.4 1.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.4 1.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 1.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 4.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 1.7 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.4 1.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.4 6.1 GO:0015250 water channel activity(GO:0015250)
0.4 3.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 8.5 GO:0004707 MAP kinase activity(GO:0004707)
0.4 2.0 GO:0070905 serine binding(GO:0070905)
0.4 1.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.4 3.6 GO:0032190 acrosin binding(GO:0032190)
0.4 4.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.4 1.6 GO:0044877 macromolecular complex binding(GO:0044877)
0.4 1.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.4 1.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.4 7.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 1.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 11.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 2.3 GO:0052658 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 1.2 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.4 2.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 2.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 3.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.4 2.3 GO:0004630 phospholipase D activity(GO:0004630)
0.4 3.7 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.4 8.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.4 1.1 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.4 2.6 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.4 3.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 6.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.4 3.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 2.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.4 12.4 GO:0042605 peptide antigen binding(GO:0042605)
0.4 1.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 3.9 GO:0031419 cobalamin binding(GO:0031419)
0.3 8.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 0.7 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.3 3.1 GO:0003678 DNA helicase activity(GO:0003678)
0.3 42.2 GO:0003823 antigen binding(GO:0003823)
0.3 3.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 1.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 1.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 1.7 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.3 2.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 1.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 5.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 1.3 GO:0008431 vitamin E binding(GO:0008431)
0.3 1.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 3.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 3.1 GO:0022821 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.3 17.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.3 0.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3 2.1 GO:0031404 chloride ion binding(GO:0031404)
0.3 6.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3 1.8 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.3 1.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3 6.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.3 5.5 GO:0008026 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.3 3.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 4.8 GO:0070513 death domain binding(GO:0070513)
0.3 1.1 GO:0034618 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.3 3.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 1.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.3 1.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 3.0 GO:0000150 recombinase activity(GO:0000150)
0.3 3.0 GO:0032052 bile acid binding(GO:0032052)
0.3 1.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.3 2.7 GO:0003909 DNA ligase activity(GO:0003909)
0.3 2.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 5.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 7.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 9.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 2.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 3.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.0 GO:0015643 toxic substance binding(GO:0015643)
0.2 2.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 5.9 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 4.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 3.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 26.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 3.3 GO:0031996 thioesterase binding(GO:0031996)
0.2 2.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 2.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 3.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 8.9 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.7 GO:0070984 SET domain binding(GO:0070984)
0.2 8.1 GO:0032451 demethylase activity(GO:0032451)
0.2 1.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 0.7 GO:0043199 sulfate binding(GO:0043199)
0.2 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 1.8 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 0.9 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 2.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 3.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 5.0 GO:0050699 WW domain binding(GO:0050699)
0.2 5.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 1.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 2.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 0.8 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 0.8 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 4.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 2.5 GO:0016866 intramolecular transferase activity(GO:0016866)
0.2 0.8 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.2 1.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 1.0 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 30.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.5 GO:0035198 miRNA binding(GO:0035198)
0.2 2.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 4.8 GO:0070840 dynein complex binding(GO:0070840)
0.2 3.3 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.2 5.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 7.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 2.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 5.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 210.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 2.5 GO:0009881 photoreceptor activity(GO:0009881)
0.2 2.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.2 6.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 0.7 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.2 1.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.2 3.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.4 GO:0019864 IgG binding(GO:0019864)
0.1 3.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 7.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.1 5.0 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.1 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 2.5 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.1 1.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.7 GO:0042166 acetylcholine binding(GO:0042166)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 4.5 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 6.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 5.8 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 5.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 3.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 5.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.7 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 5.9 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 4.3 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.1 2.0 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.1 1.6 GO:0016594 glycine binding(GO:0016594)
0.1 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.8 GO:0005113 patched binding(GO:0005113)
0.1 6.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 8.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 3.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 3.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.5 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.0 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.2 GO:0005549 odorant binding(GO:0005549)
0.1 2.0 GO:0005518 collagen binding(GO:0005518)
0.1 2.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 3.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 4.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.2 GO:0070403 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) NAD+ binding(GO:0070403)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.2 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 9.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.7 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0000149 SNARE binding(GO:0000149)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 4.5 GO:0005261 cation channel activity(GO:0005261)
0.1 0.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.5 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0043394 proteoglycan binding(GO:0043394)
0.0 3.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 1.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0019862 IgA binding(GO:0019862)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 6.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.6 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0005126 cytokine receptor binding(GO:0005126)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
1.1 5.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.0 54.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.9 2.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.8 23.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7 3.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.7 28.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.7 9.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.6 7.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.6 60.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.6 4.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.6 32.2 PID ATM PATHWAY ATM pathway
0.5 17.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 14.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 37.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 3.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 17.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 11.8 PID EPO PATHWAY EPO signaling pathway
0.4 9.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 2.4 ST STAT3 PATHWAY STAT3 Pathway
0.4 19.7 PID BCR 5PATHWAY BCR signaling pathway
0.4 12.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 3.0 ST GA12 PATHWAY G alpha 12 Pathway
0.3 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.3 4.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 6.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 1.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 3.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 9.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 3.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 36.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 2.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 2.0 PID CD40 PATHWAY CD40/CD40L signaling
0.2 2.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 11.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 6.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 4.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 5.6 PID ATR PATHWAY ATR signaling pathway
0.2 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 4.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 1.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 1.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.2 3.1 PID SHP2 PATHWAY SHP2 signaling
0.2 5.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 8.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 9.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 ST GAQ PATHWAY G alpha q Pathway
0.1 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 12.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
2.2 4.3 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
1.9 1.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.5 32.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.5 7.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.3 2.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.2 24.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.2 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.1 48.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.1 15.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.0 24.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.0 20.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.9 78.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.9 10.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.8 12.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.8 11.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.8 8.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.8 10.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.7 7.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.7 12.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 10.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 8.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.7 8.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.6 10.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.6 14.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.5 6.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.5 4.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.5 22.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.5 9.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.5 6.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 8.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.5 7.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.5 1.9 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.5 13.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 5.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 9.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 20.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.4 10.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 16.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 161.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.4 5.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.4 8.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.4 13.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.4 5.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 7.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 7.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 11.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 3.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 10.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.3 5.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 7.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 6.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 2.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 3.1 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.3 6.8 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 8.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 3.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.3 4.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 6.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 7.7 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.3 7.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 4.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 5.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 13.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 2.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 13.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 5.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 3.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 8.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 10.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 6.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 10.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.2 1.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 3.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 3.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 2.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 7.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 5.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 8.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 0.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2 7.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 13.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 9.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 4.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 13.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 1.2 REACTOME OPSINS Genes involved in Opsins
0.1 1.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 13.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 1.8 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.1 3.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 21.5 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.6 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo