ISMARA results: MNT_HEY1

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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MNT_HEY1_HEY2

Z-value: 1.05

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Transcription factors associated with MNT_HEY1_HEY2

Gene Symbol	Gene ID	Gene Info
MNT Ensembl NCBI GeneCards UniProt NextProt	ENSG00000070444.10	MAX network transcriptional repressor
HEY1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000164683.12	hes related family bHLH transcription factor with YRPW motif 1
HEY2 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000135547.4	hes related family bHLH transcription factor with YRPW motif 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HEY2	hg19_v2_chr6_+_126070726_126070768	0.65	4.6e-28	Click!
HEY1	hg19_v2_chr8_-_80680078_80680101	0.29	1.1e-05	Click!
MNT	hg19_v2_chr17_-_2304365_2304412	-0.26	9.9e-05	Click!

Activity profile of MNT_HEY1_HEY2 motif

Sorted Z-values of MNT_HEY1_HEY2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_154193009 Show fit	91.05	ENST00000368518.1 ENST00000368519.1 ENST00000368521.5	C1orf43 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 43
chr1_+_11866270 Show fit	82.57	ENST00000376497.3 ENST00000376487.3 ENST00000376496.3	CLCN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 6
chr1_-_11866034 Show fit	73.15	ENST00000376590.3	MTHFR Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_13956497 Show fit	63.91	ENST00000398361.3	GPM6B Ensembl NCBI GeneCards UniProt NextProt Show fit	glycoprotein M6B
chr1_+_11866207 Show fit	61.48	ENST00000312413.6 ENST00000346436.6	CLCN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride channel, voltage-sensitive 6
chr22_+_40390930 Show fit	61.00	ENST00000333407.6	FAM83F Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 83, member F
chr1_-_11865982 Show fit	59.46	ENST00000418034.1	MTHFR Ensembl NCBI GeneCards UniProt NextProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chr2_-_38604398 Show fit	59.32	ENST00000443098.1 ENST00000449130.1 ENST00000378954.4 ENST00000539122.1 ENST00000419554.2 ENST00000451483.1 ENST00000406122.1	ATL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	atlastin GTPase 2
chr4_+_76439665 Show fit	58.46	ENST00000508105.1 ENST00000311638.3 ENST00000380837.3 ENST00000507556.1 ENST00000504190.1 ENST00000507885.1 ENST00000502620.1 ENST00000514480.1	THAP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	THAP domain containing 6
chr16_+_66914264 Show fit	56.41	ENST00000311765.2 ENST00000568869.1 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1	PDP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 2
chrX_-_13956737 Show fit	56.17	ENST00000454189.2	GPM6B Ensembl NCBI GeneCards UniProt NextProt Show fit	glycoprotein M6B
chr1_-_241520525 Show fit	55.95	ENST00000366565.1	RGS7 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of G-protein signaling 7
chr4_+_128651530 Show fit	53.61	ENST00000281154.4	SLC25A31 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr19_-_5340730 Show fit	48.17	ENST00000372412.4 ENST00000357368.4 ENST00000262963.6 ENST00000348075.2 ENST00000353284.2	PTPRS Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase, receptor type, S
chr9_+_74526384 Show fit	46.69	ENST00000334731.2 ENST00000377031.3	C9orf85 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 85
chr5_-_131132614 Show fit	46.23	ENST00000307968.7 ENST00000307954.8	FNIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	folliculin interacting protein 1
chr12_+_130554803 Show fit	44.36	ENST00000535487.1	RP11-474D1.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-474D1.2
chr1_-_241520385 Show fit	40.97	ENST00000366564.1	RGS7 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of G-protein signaling 7
chr15_+_75118888 Show fit	40.84	ENST00000395018.4	CPLX3 Ensembl NCBI GeneCards UniProt NextProt Show fit	complexin 3
chr16_+_6533380 Show fit	40.60	ENST00000552089.1	RBFOX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_203499901 Show fit	40.53	ENST00000303116.6 ENST00000392238.2	FAM117B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 117, member B
chr22_-_36903101 Show fit	40.25	ENST00000397224.4	FOXRED2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FAD-dependent oxidoreductase domain containing 2
chr19_-_10764509 Show fit	40.16	ENST00000591501.1	ILF3-AS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ILF3 antisense RNA 1 (head to head)
chr22_-_36903069 Show fit	39.35	ENST00000216187.6 ENST00000423980.1	FOXRED2 Ensembl NCBI GeneCards UniProt NextProt Show fit	FAD-dependent oxidoreductase domain containing 2
chr7_+_72742178 Show fit	37.11	ENST00000442793.1 ENST00000413573.2 ENST00000252037.4	FKBP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	FK506 binding protein 6, 36kDa
chr12_-_122751002 Show fit	35.93	ENST00000267199.4	VPS33A Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr14_-_81687197 Show fit	35.19	ENST00000553612.1	GTF2A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr1_-_52831796 Show fit	35.00	ENST00000284376.3 ENST00000438831.1 ENST00000371586.2	CC2D1B Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil and C2 domain containing 1B
chr7_+_72742162 Show fit	33.01	ENST00000431982.2	FKBP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	FK506 binding protein 6, 36kDa
chr11_-_66336060 Show fit	32.71	ENST00000310325.5	CTSF Ensembl NCBI GeneCards UniProt NextProt Show fit	cathepsin F
chr14_-_81687575 Show fit	32.61	ENST00000434192.2	GTF2A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr6_+_31865552 Show fit	31.98	ENST00000469372.1 ENST00000497706.1	C2 Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 2
chr15_-_83316254 Show fit	31.76	ENST00000567678.1 ENST00000450751.2	CPEB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr11_+_125774362 Show fit	31.28	ENST00000530414.1 ENST00000530129.2	DDX25 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr5_+_55033845 Show fit	31.09	ENST00000353507.5 ENST00000514278.2 ENST00000505374.1 ENST00000506511.1	DDX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr1_+_154193325 Show fit	30.96	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin associated protein 2-like
chr11_-_116968987 Show fit	30.61	ENST00000434315.2 ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2	SIK3 Ensembl NCBI GeneCards UniProt NextProt Show fit	SIK family kinase 3
chrX_+_153524024 Show fit	30.23	ENST00000369915.3 ENST00000217905.7	TKTL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transketolase-like 1
chrX_+_38420783 Show fit	29.72	ENST00000422612.2 ENST00000286824.6 ENST00000545599.1	TSPAN7 Ensembl NCBI GeneCards UniProt NextProt Show fit	tetraspanin 7
chr11_+_125774258 Show fit	29.48	ENST00000263576.6	DDX25 Ensembl NCBI GeneCards UniProt NextProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr11_+_65479702 Show fit	29.21	ENST00000530446.1 ENST00000534104.1 ENST00000530605.1 ENST00000528198.1 ENST00000531880.1 ENST00000534650.1	KAT5 Ensembl NCBI GeneCards UniProt NextProt Show fit	K(lysine) acetyltransferase 5
chr19_+_2977444 Show fit	29.04	ENST00000246112.4 ENST00000453329.1 ENST00000482627.1 ENST00000452088.1	TLE6 Ensembl NCBI GeneCards UniProt NextProt Show fit	transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr1_+_233086326 Show fit	29.02	ENST00000366628.5 ENST00000366627.4	NTPCR Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoside-triphosphatase, cancer-related
chr11_-_66725837 Show fit	29.00	ENST00000393958.2 ENST00000393960.1 ENST00000524491.1 ENST00000355677.3	PC Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate carboxylase
chr20_+_44657845 Show fit	28.64	ENST00000243964.3	SLC12A5 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 12 (potassium/chloride transporter), member 5
chr17_-_6915646 Show fit	28.35	ENST00000574377.1 ENST00000399541.2 ENST00000399540.2 ENST00000575727.1 ENST00000573939.1	AC027763.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein
chr8_-_67341208 Show fit	27.92	ENST00000499642.1	RP11-346I3.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-346I3.4
chr22_+_41777927 Show fit	27.76	ENST00000266304.4	TEF Ensembl NCBI GeneCards UniProt NextProt Show fit	thyrotrophic embryonic factor
chr8_+_95908041 Show fit	27.69	ENST00000396113.1 ENST00000519136.1	NDUFAF6 Ensembl NCBI GeneCards UniProt NextProt Show fit	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr22_+_24891210 Show fit	27.65	ENST00000382760.2	UPB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ureidopropionase, beta
chr5_-_133706695 Show fit	27.62	ENST00000521755.1 ENST00000523054.1 ENST00000435240.2 ENST00000609654.1 ENST00000536186.1 ENST00000609383.1	CDKL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase-like 3
chr9_+_139871948 Show fit	27.32	ENST00000224167.2 ENST00000457950.1 ENST00000371625.3 ENST00000371623.3	PTGDS Ensembl NCBI GeneCards UniProt NextProt Show fit	prostaglandin D2 synthase 21kDa (brain)
chr12_+_58013693 Show fit	26.87	ENST00000320442.4 ENST00000379218.2	SLC26A10 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 26, member 10
chr2_-_68384603 Show fit	26.35	ENST00000406245.2 ENST00000409164.1 ENST00000295121.6	WDR92 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 92
chr17_+_17942684 Show fit	25.76	ENST00000376345.3	GID4 Ensembl NCBI GeneCards UniProt NextProt Show fit	GID complex subunit 4
chr4_-_5891918 Show fit	25.74	ENST00000512574.1	CRMP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	collapsin response mediator protein 1
chr12_+_50355647 Show fit	25.28	ENST00000293599.6	AQP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	aquaporin 5
chr16_+_4897632 Show fit	25.11	ENST00000262376.6	UBN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ubinuclein 1
chr10_+_104474207 Show fit	25.11	ENST00000602831.1 ENST00000369893.5	SFXN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	sideroflexin 2
chr11_-_777467 Show fit	24.92	ENST00000397472.2 ENST00000524550.1 ENST00000319863.8 ENST00000526325.1 ENST00000442059.2	PDDC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Parkinson disease 7 domain containing 1
chr19_+_5681011 Show fit	24.72	ENST00000581893.1 ENST00000411793.2 ENST00000301382.4 ENST00000581773.1 ENST00000423665.2 ENST00000583928.1 ENST00000342970.2 ENST00000422535.2 ENST00000581521.1 ENST00000339423.2	HSD11B1L Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (11-beta) dehydrogenase 1-like
chr16_-_4588469 Show fit	24.62	ENST00000588381.1 ENST00000563332.2	CDIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cell death-inducing p53 target 1
chr2_+_17721920 Show fit	24.60	ENST00000295156.4	VSNL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	visinin-like 1
chr11_-_61684962 Show fit	24.57	ENST00000394836.2	RAB3IL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB3A interacting protein (rabin3)-like 1
chr17_-_2614927 Show fit	24.14	ENST00000435359.1	CLUH Ensembl NCBI GeneCards UniProt NextProt Show fit	clustered mitochondria (cluA/CLU1) homolog
chr1_+_9599540 Show fit	23.76	ENST00000302692.6	SLC25A33 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr19_+_41903709 Show fit	23.40	ENST00000542943.1 ENST00000457836.2	BCKDHA Ensembl NCBI GeneCards UniProt NextProt Show fit	branched chain keto acid dehydrogenase E1, alpha polypeptide
chr19_-_49137790 Show fit	23.37	ENST00000599385.1	DBP Ensembl NCBI GeneCards UniProt NextProt Show fit	D site of albumin promoter (albumin D-box) binding protein
chr17_-_41465674 Show fit	23.12	ENST00000592135.1 ENST00000587874.1 ENST00000588654.1 ENST00000592094.1	LINC00910 Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 910
chr11_-_64511789 Show fit	23.09	ENST00000419843.1 ENST00000394430.1	RASGRP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_47164386 Show fit	23.03	ENST00000391916.2 ENST00000410105.2	DACT3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled-binding antagonist of beta-catenin 3
chr19_-_46974741 Show fit	22.90	ENST00000313683.10 ENST00000602246.1	PNMAL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	paraneoplastic Ma antigen family-like 1
chr10_-_120514720 Show fit	22.60	ENST00000369151.3 ENST00000340214.4	CACUL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CDK2-associated, cullin domain 1
chr16_-_4897266 Show fit	22.57	ENST00000591451.1 ENST00000436648.5 ENST00000381983.3 ENST00000588297.1 ENST00000321919.9	GLYR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	glyoxylate reductase 1 homolog (Arabidopsis)
chr17_+_17942594 Show fit	22.54	ENST00000268719.4	GID4 Ensembl NCBI GeneCards UniProt NextProt Show fit	GID complex subunit 4
chr2_+_173420697 Show fit	22.41	ENST00000282077.3 ENST00000392571.2 ENST00000410055.1	PDK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehydrogenase kinase, isozyme 1
chr19_-_46974664 Show fit	22.33	ENST00000438932.2	PNMAL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	paraneoplastic Ma antigen family-like 1
chr17_-_7137582 Show fit	22.10	ENST00000575756.1 ENST00000575458.1	DVL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	dishevelled segment polarity protein 2
chr7_+_97361218 Show fit	22.01	ENST00000319273.5	TAC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tachykinin, precursor 1
chr3_-_57678772 Show fit	21.99	ENST00000311128.5	DENND6A Ensembl NCBI GeneCards UniProt NextProt Show fit	DENN/MADD domain containing 6A
chr14_-_92572894 Show fit	21.96	ENST00000532032.1 ENST00000506466.1 ENST00000555381.1 ENST00000557311.1 ENST00000554592.1 ENST00000554672.1 ENST00000553491.1 ENST00000556220.1 ENST00000502250.1 ENST00000503767.1 ENST00000393287.5 ENST00000340660.6 ENST00000545170.1 ENST00000429774.2	ATXN3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ataxin 3
chr3_-_45883558 Show fit	21.31	ENST00000445698.1 ENST00000296135.6	LZTFL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine zipper transcription factor-like 1
chr11_+_9595180 Show fit	21.30	ENST00000450114.2	WEE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	WEE1 G2 checkpoint kinase
chr1_-_113498616 Show fit	21.28	ENST00000433570.4 ENST00000538576.1 ENST00000458229.1	SLC16A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 16 (monocarboxylate transporter), member 1
chr9_-_139922726 Show fit	20.83	ENST00000265662.5 ENST00000371605.3	ABCA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 2
chr20_+_42839600 Show fit	20.72	ENST00000439943.1 ENST00000437730.1	OSER1-AS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	OSER1 antisense RNA 1 (head to head)
chr18_+_23806437 Show fit	20.52	ENST00000578121.1	TAF4B Ensembl NCBI GeneCards UniProt NextProt Show fit	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr16_+_84178874 Show fit	20.22	ENST00000378553.5	DNAAF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, axonemal, assembly factor 1
chr12_+_54332535 Show fit	19.92	ENST00000243056.3	HOXC13 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C13
chr19_-_49137762 Show fit	19.86	ENST00000593500.1	DBP Ensembl NCBI GeneCards UniProt NextProt Show fit	D site of albumin promoter (albumin D-box) binding protein
chr18_-_21977748 Show fit	19.79	ENST00000399441.4 ENST00000319481.3	OSBPL1A Ensembl NCBI GeneCards UniProt NextProt Show fit	oxysterol binding protein-like 1A
chr2_-_220042825 Show fit	19.78	ENST00000409789.1	CNPPD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin Pas1/PHO80 domain containing 1
chr20_+_42839722 Show fit	19.64	ENST00000442383.1 ENST00000435163.1	OSER1-AS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	OSER1 antisense RNA 1 (head to head)
chr9_+_6757634 Show fit	19.47	ENST00000543771.1 ENST00000401787.3 ENST00000381306.3 ENST00000381309.3	KDM4C Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine (K)-specific demethylase 4C
chr1_-_15911510 Show fit	19.45	ENST00000375826.3	AGMAT Ensembl NCBI GeneCards UniProt NextProt Show fit	agmatine ureohydrolase (agmatinase)
chr17_+_76311791 Show fit	19.40	ENST00000586321.1	AC061992.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC061992.2
chr19_-_12833361 Show fit	19.13	ENST00000592287.1	TNPO2 Ensembl NCBI GeneCards UniProt NextProt Show fit	transportin 2
chr8_+_142402089 Show fit	18.98	ENST00000521578.1 ENST00000520105.1 ENST00000523147.1	PTP4A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase type IVA, member 3
chr7_+_148959262 Show fit	18.88	ENST00000434415.1	ZNF783 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger family member 783
chr18_+_9136758 Show fit	18.64	ENST00000383440.2 ENST00000262126.4 ENST00000577992.1	ANKRD12 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 12
chr2_-_50574856 Show fit	18.58	ENST00000342183.5	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr11_-_9781068 Show fit	18.39	ENST00000500698.1	RP11-540A21.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-540A21.2
chr5_+_149737202 Show fit	18.39	ENST00000451292.1 ENST00000377797.3 ENST00000445265.2 ENST00000323668.7 ENST00000439160.2 ENST00000394269.3 ENST00000427724.2 ENST00000504761.2 ENST00000513346.1 ENST00000515516.1	TCOF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Treacher Collins-Franceschetti syndrome 1
chr12_-_114404111 Show fit	18.27	ENST00000545145.2 ENST00000392561.3 ENST00000261741.5	RBM19 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 19
chr11_+_121322832 Show fit	18.18	ENST00000260197.7	SORL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sortilin-related receptor, L(DLR class) A repeats containing
chr7_-_50132801 Show fit	18.18	ENST00000419417.1	ZPBP Ensembl NCBI GeneCards UniProt NextProt Show fit	zona pellucida binding protein
chr11_-_125366089 Show fit	17.97	ENST00000366139.3 ENST00000278919.3	FEZ1 Ensembl NCBI GeneCards UniProt NextProt Show fit	fasciculation and elongation protein zeta 1 (zygin I)
chr7_-_50132860 Show fit	17.93	ENST00000046087.2	ZPBP Ensembl NCBI GeneCards UniProt NextProt Show fit	zona pellucida binding protein
chr7_+_97361388 Show fit	17.84	ENST00000350485.4 ENST00000346867.4	TAC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tachykinin, precursor 1
chr1_-_151319283 Show fit	17.79	ENST00000392746.3	RFX5 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X, 5 (influences HLA class II expression)
chrX_+_102469997 Show fit	17.41	ENST00000372695.5 ENST00000372691.3	BEX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	brain expressed, X-linked 4
chr16_+_11762270 Show fit	17.40	ENST00000329565.5	SNN Ensembl NCBI GeneCards UniProt NextProt Show fit	stannin
chr2_+_10183651 Show fit	17.27	ENST00000305883.1	KLF11 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel-like factor 11
chr5_-_131132658 Show fit	17.21	ENST00000514667.1 ENST00000511848.1 ENST00000510461.1	CTC-432M15.3 Ensembl NCBI GeneCards UniProt NextProt Show fit FNIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Folliculin-interacting protein 1 folliculin interacting protein 1
chr3_+_147127142 Show fit	17.10	ENST00000282928.4	ZIC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Zic family member 1
chr7_-_103629963 Show fit	17.06	ENST00000428762.1 ENST00000343529.5 ENST00000424685.2	RELN Ensembl NCBI GeneCards UniProt NextProt Show fit	reelin
chr2_-_220083671 Show fit	17.05	ENST00000439002.2	ABCB6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr9_+_130159504 Show fit	17.03	ENST00000373352.1 ENST00000373360.3	SLC2A8 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 8
chr5_-_172198190 Show fit	17.03	ENST00000239223.3	DUSP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 1
chr15_-_83316711 Show fit	16.83	ENST00000568128.1	CPEB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr9_+_131709966 Show fit	16.81	ENST00000372577.2	NUP188 Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 188kDa
chr17_+_30813576 Show fit	16.80	ENST00000313401.3	CDK5R1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr2_-_220083692 Show fit	16.73	ENST00000265316.3	ABCB6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr7_+_2559399 Show fit	16.68	ENST00000222725.5 ENST00000359574.3	LFNG Ensembl NCBI GeneCards UniProt NextProt Show fit	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_111878483 Show fit	16.50	ENST00000308659.8 ENST00000357757.2 ENST00000393253.2 ENST00000337565.5 ENST00000393256.3	BCL2L11 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2-like 11 (apoptosis facilitator)
chr12_-_54020107 Show fit	16.40	ENST00000588232.1 ENST00000548446.2 ENST00000420353.2 ENST00000591397.1 ENST00000415113.1	ATF7 Ensembl NCBI GeneCards UniProt NextProt Show fit	activating transcription factor 7
chr18_+_56530794 Show fit	16.28	ENST00000590285.1 ENST00000586085.1 ENST00000589288.1	ZNF532 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 532
chr3_+_33318914 Show fit	16.27	ENST00000484457.1 ENST00000538892.1 ENST00000538181.1 ENST00000446237.3 ENST00000507198.1	FBXL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box and leucine-rich repeat protein 2
chr18_-_13726510 Show fit	16.27	ENST00000322247.3 ENST00000592976.1 ENST00000402563.1 ENST00000591269.1	FAM210A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 210, member A
chrX_-_102319092 Show fit	16.26	ENST00000372728.3	BEX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	brain expressed, X-linked 1
chr6_-_99873145 Show fit	16.21	ENST00000369239.5 ENST00000438806.1	PNISR Ensembl NCBI GeneCards UniProt NextProt Show fit	PNN-interacting serine/arginine-rich protein
chr6_-_35109080 Show fit	16.21	ENST00000486638.1 ENST00000505400.1 ENST00000412155.2 ENST00000373979.2 ENST00000507706.1 ENST00000444780.2 ENST00000492680.2	TCP11 Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 11, testis-specific
chr9_+_17135016 Show fit	16.21	ENST00000425824.1 ENST00000262360.5 ENST00000380641.4	CNTLN Ensembl NCBI GeneCards UniProt NextProt Show fit	centlein, centrosomal protein
chr16_-_70719925 Show fit	16.21	ENST00000338779.6	MTSS1L Ensembl NCBI GeneCards UniProt NextProt Show fit	metastasis suppressor 1-like
chr8_-_110656995 Show fit	16.06	ENST00000276646.9 ENST00000533065.1	SYBU Ensembl NCBI GeneCards UniProt NextProt Show fit	syntabulin (syntaxin-interacting)
chr9_-_100684845 Show fit	15.68	ENST00000375119.3	C9orf156 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 156
chr18_-_21017817 Show fit	15.63	ENST00000542162.1 ENST00000383233.3 ENST00000582336.1 ENST00000450466.2 ENST00000578520.1 ENST00000399707.1	TMEM241 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 241
chr20_+_30946106 Show fit	15.62	ENST00000375687.4 ENST00000542461.1	ASXL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	additional sex combs like 1 (Drosophila)
chr12_-_45270151 Show fit	15.57	ENST00000429094.2	NELL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr9_-_139922631 Show fit	15.54	ENST00000341511.6	ABCA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 2
chr14_+_96505659 Show fit	15.51	ENST00000555004.1	C14orf132 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 132
chr12_+_117176090 Show fit	15.45	ENST00000257575.4 ENST00000407967.3 ENST00000392549.2	RNFT2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein, transmembrane 2
chr12_-_45270077 Show fit	15.44	ENST00000551601.1 ENST00000549027.1 ENST00000452445.2	NELL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr9_-_135819987 Show fit	15.42	ENST00000298552.3 ENST00000403810.1	TSC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tuberous sclerosis 1
chr17_+_73975292 Show fit	15.36	ENST00000397640.1 ENST00000416485.1 ENST00000588202.1 ENST00000590676.1 ENST00000586891.1	TEN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	TEN1 CST complex subunit
chr13_+_42031679 Show fit	15.34	ENST00000379359.3	RGCC Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of cell cycle
chr6_-_39197226 Show fit	15.32	ENST00000359534.3	KCNK5 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium channel, subfamily K, member 5
chr13_+_103451399 Show fit	15.30	ENST00000257336.1 ENST00000448849.2	BIVM Ensembl NCBI GeneCards UniProt NextProt Show fit	basic, immunoglobulin-like variable motif containing
chr3_+_50712672 Show fit	15.29	ENST00000266037.9	DOCK3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dedicator of cytokinesis 3
chr9_+_130159409 Show fit	15.18	ENST00000373371.3	SLC2A8 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 8
chr7_-_44365020 Show fit	15.17	ENST00000395747.2 ENST00000347193.4 ENST00000346990.4 ENST00000258682.6 ENST00000353625.4 ENST00000421607.1 ENST00000424197.1 ENST00000502837.2 ENST00000350811.3 ENST00000395749.2	CAMK2B Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase II beta
chr15_-_83316087 Show fit	15.08	ENST00000568757.1	CPEB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoplasmic polyadenylation element binding protein 1
chr4_+_176986978 Show fit	15.07	ENST00000508596.1 ENST00000393643.2	WDR17 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 17
chr2_+_17721230 Show fit	15.05	ENST00000457525.1	VSNL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	visinin-like 1
chr7_+_72848092 Show fit	14.98	ENST00000344575.3	FZD9 Ensembl NCBI GeneCards UniProt NextProt Show fit	frizzled family receptor 9
chr17_-_74722672 Show fit	14.94	ENST00000397625.4 ENST00000445478.2	JMJD6 Ensembl NCBI GeneCards UniProt NextProt Show fit	jumonji domain containing 6
chr1_+_92414928 Show fit	14.89	ENST00000362005.3 ENST00000370389.2 ENST00000399546.2 ENST00000423434.1 ENST00000394530.3 ENST00000440509.1	BRDT Ensembl NCBI GeneCards UniProt NextProt Show fit	bromodomain, testis-specific
chrX_-_48433275 Show fit	14.88	ENST00000376775.2	AC115618.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Uncharacterized protein; cDNA FLJ26048 fis, clone PRS02384
chr11_+_7534999 Show fit	14.82	ENST00000528947.1 ENST00000299492.4	PPFIBP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_150229554 Show fit	14.80	ENST00000369111.4	CA14 Ensembl NCBI GeneCards UniProt NextProt Show fit	carbonic anhydrase XIV
chrX_-_107979616 Show fit	14.78	ENST00000372129.2	IRS4 Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin receptor substrate 4
chr10_-_75634219 Show fit	14.74	ENST00000305762.7	CAMK2G Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase II gamma
chr6_-_151773232 Show fit	14.74	ENST00000444024.1 ENST00000367303.4	RMND1 Ensembl NCBI GeneCards UniProt NextProt Show fit	required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr6_+_127587755 Show fit	14.66	ENST00000368314.1 ENST00000476956.1 ENST00000609447.1 ENST00000356799.2 ENST00000477776.1 ENST00000609944.1	RNF146 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 146
chr19_-_48018203 Show fit	14.65	ENST00000595227.1 ENST00000593761.1 ENST00000263354.3	NAPA Ensembl NCBI GeneCards UniProt NextProt Show fit	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr6_-_84937314 Show fit	14.64	ENST00000257766.4 ENST00000403245.3	KIAA1009 Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA1009
chr7_+_43152191 Show fit	14.60	ENST00000395891.2	HECW1 Ensembl NCBI GeneCards UniProt NextProt Show fit	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr3_-_42306248 Show fit	14.57	ENST00000334681.5	CCK Ensembl NCBI GeneCards UniProt NextProt Show fit	cholecystokinin
chr10_-_44070016 Show fit	14.56	ENST00000374446.2 ENST00000426961.1 ENST00000535642.1	ZNF239 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 239
chrX_+_11776410 Show fit	14.55	ENST00000361672.2	MSL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	male-specific lethal 3 homolog (Drosophila)
chr19_-_12833164 Show fit	14.54	ENST00000356861.5	TNPO2 Ensembl NCBI GeneCards UniProt NextProt Show fit	transportin 2
chr21_+_35747773 Show fit	14.51	ENST00000399292.3 ENST00000399299.1 ENST00000399295.2	SMIM11 Ensembl NCBI GeneCards UniProt NextProt Show fit	small integral membrane protein 11
chr17_+_48172639 Show fit	14.51	ENST00000503176.1 ENST00000503614.1	PDK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehydrogenase kinase, isozyme 2
chr7_-_44365216 Show fit	14.50	ENST00000358707.3 ENST00000457475.1 ENST00000440254.2	CAMK2B Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase II beta
chr6_-_35109145 Show fit	14.44	ENST00000373974.4 ENST00000244645.3	TCP11 Ensembl NCBI GeneCards UniProt NextProt Show fit	t-complex 11, testis-specific
chr19_-_45909585 Show fit	14.42	ENST00000593226.1 ENST00000418234.2	PPP1R13L Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory subunit 13 like
chr14_-_93799360 Show fit	14.41	ENST00000334746.5 ENST00000554565.1 ENST00000298896.3	BTBD7 Ensembl NCBI GeneCards UniProt NextProt Show fit	BTB (POZ) domain containing 7
chr10_-_11653753 Show fit	14.34	ENST00000609104.1	USP6NL Ensembl NCBI GeneCards UniProt NextProt Show fit	USP6 N-terminal like
chr22_-_38577782 Show fit	14.19	ENST00000430886.1 ENST00000332509.3 ENST00000447598.2 ENST00000435484.1 ENST00000402064.1 ENST00000436218.1	PLA2G6 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase A2, group VI (cytosolic, calcium-independent)
chr17_-_34890709 Show fit	14.14	ENST00000544606.1	MYO19 Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin XIX
chr12_+_54674482 Show fit	14.06	ENST00000547708.1 ENST00000340913.6 ENST00000551702.1 ENST00000330752.8 ENST00000547276.1	HNRNPA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	heterogeneous nuclear ribonucleoprotein A1
chr2_-_220108309 Show fit	14.01	ENST00000409640.1	GLB1L Ensembl NCBI GeneCards UniProt NextProt Show fit	galactosidase, beta 1-like
chr11_+_67159416 Show fit	13.92	ENST00000307980.2 ENST00000544620.1	RAD9A Ensembl NCBI GeneCards UniProt NextProt Show fit	RAD9 homolog A (S. pombe)
chr10_+_49514698 Show fit	13.87	ENST00000432379.1 ENST00000429041.1 ENST00000374189.1	MAPK8 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 8
chr17_-_37309480 Show fit	13.86	ENST00000539608.1	PLXDC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	plexin domain containing 1
chr19_-_18632861 Show fit	13.83	ENST00000262809.4	ELL Ensembl NCBI GeneCards UniProt NextProt Show fit	elongation factor RNA polymerase II
chrX_-_153523462 Show fit	13.82	ENST00000361930.3 ENST00000369926.1	TEX28 Ensembl NCBI GeneCards UniProt NextProt Show fit	testis expressed 28
chr15_-_64126084 Show fit	13.79	ENST00000560316.1 ENST00000443617.2 ENST00000560462.1 ENST00000558532.1 ENST00000561400.1	HERC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr9_-_131709858 Show fit	13.79	ENST00000372586.3	DOLK Ensembl NCBI GeneCards UniProt NextProt Show fit	dolichol kinase
chr22_-_38577731 Show fit	13.77	ENST00000335539.3	PLA2G6 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase A2, group VI (cytosolic, calcium-independent)
chr12_-_123849374 Show fit	13.76	ENST00000602398.1 ENST00000602750.1	SBNO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	strawberry notch homolog 1 (Drosophila)
chr13_-_36788718 Show fit	13.75	ENST00000317764.6 ENST00000379881.3	SOHLH2 Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr10_-_6019455 Show fit	13.60	ENST00000530685.1 ENST00000397255.3 ENST00000379971.1 ENST00000528354.1 ENST00000397250.2 ENST00000429135.2	IL15RA Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 15 receptor, alpha
chr22_+_18593446 Show fit	13.60	ENST00000316027.6	TUBA8 Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin, alpha 8
chr13_+_35516390 Show fit	13.53	ENST00000540320.1 ENST00000400445.3 ENST00000310336.4	NBEA Ensembl NCBI GeneCards UniProt NextProt Show fit	neurobeachin
chr7_-_22396533 Show fit	13.51	ENST00000344041.6	RAPGEF5 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 5
chrX_+_54556633 Show fit	13.42	ENST00000336470.4 ENST00000360845.2	GNL3L Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)-like
chr3_+_10857885 Show fit	13.36	ENST00000254488.2 ENST00000454147.1	SLC6A11 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 6 (neurotransmitter transporter), member 11
chr21_+_34697258 Show fit	13.34	ENST00000442071.1 ENST00000442357.2	IFNAR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon (alpha, beta and omega) receptor 1
chr10_-_99447024 Show fit	13.33	ENST00000370626.3	AVPI1 Ensembl NCBI GeneCards UniProt NextProt Show fit	arginine vasopressin-induced 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MNT_HEY1_HEY2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.5	132.6	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
24.1	48.2	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
17.5	69.9	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
15.5	124.2	GO:0034587	piRNA metabolic process(GO:0034587)
13.9	138.5	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
13.3	39.9	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
11.7	11.7	GO:0045347	MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
10.2	30.7	GO:1902490	regulation of sperm capacitation(GO:1902490)
10.1	30.2	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
9.7	29.0	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
9.2	27.6	GO:0019482	beta-alanine metabolic process(GO:0019482)
8.6	25.7	GO:1904530	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
8.3	25.0	GO:0051039	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
8.3	16.5	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
8.0	8.0	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
8.0	63.7	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
7.9	23.8	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
7.4	14.7	GO:0070129	regulation of mitochondrial translation(GO:0070129)
7.3	14.7	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
7.3	36.4	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
7.2	28.6	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
7.2	28.6	GO:0035879	plasma membrane lactate transport(GO:0035879)
7.0	28.0	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
6.7	6.7	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
6.4	19.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
6.1	18.3	GO:1903401	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
6.1	18.2	GO:1902960	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
5.8	29.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
5.6	101.3	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
5.6	16.8	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
5.6	22.4	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
5.6	16.7	GO:0014807	regulation of somitogenesis(GO:0014807)
5.5	22.0	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
5.5	16.4	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
5.3	144.4	GO:0006884	cell volume homeostasis(GO:0006884)
5.3	10.6	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
5.2	15.6	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
5.2	15.6	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
5.2	5.2	GO:0052803	histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
5.1	25.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
5.1	15.3	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
5.1	25.3	GO:0015670	carbon dioxide transport(GO:0015670)
5.0	15.0	GO:1990523	negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
5.0	20.0	GO:1902075	cellular response to salt(GO:1902075)
4.9	19.6	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.9	19.4	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
4.8	24.2	GO:1903564	regulation of protein localization to cilium(GO:1903564)
4.6	9.3	GO:0003250	cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
4.6	13.9	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
4.5	75.9	GO:0090129	positive regulation of synapse maturation(GO:0090129)
4.3	30.2	GO:0006772	thiamine metabolic process(GO:0006772)
4.3	25.5	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
4.2	16.9	GO:0033123	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
4.2	25.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
4.2	29.3	GO:0071494	cellular response to UV-C(GO:0071494)
4.1	24.7	GO:1990504	dense core granule exocytosis(GO:1990504)
4.1	4.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
4.0	19.9	GO:1990253	cellular response to leucine starvation(GO:1990253)
3.8	23.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
3.8	11.5	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
3.8	3.8	GO:0035106	operant conditioning(GO:0035106)
3.8	11.3	GO:0019858	cytosine metabolic process(GO:0019858)
3.8	7.5	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
3.7	22.3	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
3.7	11.1	GO:0003285	septum secundum development(GO:0003285)
3.6	18.1	GO:0003431	growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
3.6	39.3	GO:0015886	heme transport(GO:0015886)
3.5	10.6	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
3.5	10.6	GO:0003358	noradrenergic neuron development(GO:0003358)
3.5	3.5	GO:0051885	positive regulation of anagen(GO:0051885)
3.5	24.5	GO:0019532	oxalate transport(GO:0019532)
3.5	27.7	GO:0070544	histone H3-K36 demethylation(GO:0070544)
3.4	10.3	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
3.4	13.7	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
3.4	17.0	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
3.4	10.1	GO:0003175	tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) negative regulation of transcription by transcription factor localization(GO:0010621)
3.2	9.6	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
3.2	3.2	GO:0072321	chaperone-mediated protein transport(GO:0072321)
3.2	9.5	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
3.1	9.4	GO:0045773	positive regulation of axon extension(GO:0045773)
3.1	15.3	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
3.0	9.1	GO:0002276	basophil activation involved in immune response(GO:0002276)
3.0	11.9	GO:0010157	response to chlorate(GO:0010157)
2.9	20.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
2.9	5.8	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.9	5.7	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
2.8	30.8	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
2.7	19.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
2.7	40.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
2.7	8.1	GO:0036090	cleavage furrow ingression(GO:0036090)
2.7	24.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
2.7	8.0	GO:0060437	lung growth(GO:0060437) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.6	10.4	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
2.5	4.9	GO:0071557	histone H3-K27 demethylation(GO:0071557)
2.5	32.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
2.4	22.0	GO:2000047	regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
2.4	14.3	GO:0098535	de novo centriole assembly(GO:0098535)
2.4	19.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
2.4	7.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
2.4	4.7	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
2.3	7.0	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
2.3	6.9	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
2.3	20.5	GO:0036158	outer dynein arm assembly(GO:0036158)
2.2	31.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
2.2	4.3	GO:0007412	axon target recognition(GO:0007412)
2.1	6.4	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
2.1	21.4	GO:0034058	endosomal vesicle fusion(GO:0034058)
2.1	8.6	GO:0009386	translational attenuation(GO:0009386)
2.1	8.5	GO:0006498	N-terminal protein lipidation(GO:0006498)
2.1	23.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
2.1	29.0	GO:0007130	synaptonemal complex assembly(GO:0007130)
2.1	4.1	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
2.1	10.3	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
2.0	8.0	GO:0000255	allantoin metabolic process(GO:0000255)
2.0	7.9	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
2.0	5.9	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.9	13.5	GO:0050893	sensory processing(GO:0050893)
1.9	9.6	GO:0086053	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.9	3.8	GO:0051026	chiasma assembly(GO:0051026)
1.9	5.6	GO:0097359	UDP-glucosylation(GO:0097359)
1.9	5.6	GO:0032053	ciliary basal body organization(GO:0032053)
1.8	3.6	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
1.8	32.2	GO:0007141	male meiosis I(GO:0007141)
1.8	26.7	GO:0014029	neural crest formation(GO:0014029)
1.8	5.3	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
1.8	23.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
1.8	7.0	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
1.7	29.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
1.7	10.4	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.7	6.9	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
1.7	6.8	GO:0021784	postganglionic parasympathetic fiber development(GO:0021784)
1.7	5.1	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.7	5.1	GO:0009183	ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
1.7	10.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.7	5.0	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.7	8.4	GO:0071543	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.7	10.0	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
1.6	11.5	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
1.6	4.9	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
1.6	16.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
1.6	8.2	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
1.6	11.4	GO:0048318	axial mesoderm development(GO:0048318)
1.6	26.2	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
1.6	8.0	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
1.6	6.3	GO:0015808	L-alanine transport(GO:0015808)
1.6	4.7	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
1.6	25.3	GO:0045475	locomotor rhythm(GO:0045475)
1.6	9.4	GO:0018095	protein polyglutamylation(GO:0018095)
1.6	4.7	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
1.5	15.3	GO:0030322	stabilization of membrane potential(GO:0030322)
1.5	6.1	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.5	6.1	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
1.5	4.5	GO:1901859	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.5	10.5	GO:0007256	activation of JNKK activity(GO:0007256)
1.5	10.5	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.5	20.8	GO:0035878	nail development(GO:0035878)
1.5	1.5	GO:0006543	glutamine catabolic process(GO:0006543)
1.5	11.7	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
1.4	8.7	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
1.4	47.7	GO:0090140	regulation of mitochondrial fission(GO:0090140)
1.4	2.9	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
1.4	5.7	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
1.4	7.1	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
1.4	9.8	GO:0045007	depurination(GO:0045007)
1.4	5.6	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
1.4	37.3	GO:0000729	DNA double-strand break processing(GO:0000729)
1.4	20.7	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
1.3	4.0	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.3	5.3	GO:1904354	negative regulation of telomere capping(GO:1904354)
1.3	6.6	GO:0009233	menaquinone metabolic process(GO:0009233)
1.3	3.9	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
1.3	7.7	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
1.3	5.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
1.3	5.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.3	1.3	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
1.3	6.4	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3	8.8	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
1.3	15.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
1.2	2.5	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.2	3.7	GO:0061055	myotome development(GO:0061055)
1.2	18.3	GO:1903358	regulation of Golgi organization(GO:1903358)
1.2	7.3	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of synaptic transmission, GABAergic(GO:0032229)
1.2	12.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
1.2	9.6	GO:1901525	negative regulation of macromitophagy(GO:1901525)
1.2	9.6	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
1.2	3.6	GO:0007497	posterior midgut development(GO:0007497)
1.2	2.4	GO:0060364	frontal suture morphogenesis(GO:0060364)
1.2	21.4	GO:0019371	cyclooxygenase pathway(GO:0019371)
1.2	9.5	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.2	8.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
1.2	8.2	GO:0055089	fatty acid homeostasis(GO:0055089)
1.2	13.9	GO:0047484	regulation of response to osmotic stress(GO:0047484)
1.2	1.2	GO:1902961	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.1	13.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.1	13.7	GO:0006108	malate metabolic process(GO:0006108)
1.1	13.7	GO:0006657	CDP-choline pathway(GO:0006657)
1.1	6.8	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
1.1	10.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
1.1	4.5	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.1	11.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.1	16.8	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
1.1	25.8	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
1.1	2.2	GO:0006907	pinocytosis(GO:0006907)
1.1	13.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
1.1	6.6	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.1	3.3	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.1	10.8	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
1.1	7.5	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.1	3.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.1	2.1	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
1.1	3.2	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.1	12.7	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
1.0	5.2	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
1.0	9.3	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
1.0	8.2	GO:0006531	aspartate metabolic process(GO:0006531)
1.0	4.1	GO:0007163	establishment or maintenance of cell polarity(GO:0007163)
1.0	19.0	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
1.0	3.0	GO:1901993	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.0	3.0	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
1.0	2.0	GO:0031133	regulation of axon diameter(GO:0031133)
1.0	4.9	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.0	4.9	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
1.0	2.9	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
1.0	6.7	GO:2000773	negative regulation of cellular senescence(GO:2000773)
1.0	1.9	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.9	0.9	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.9	67.7	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.9	8.4	GO:0070459	prolactin secretion(GO:0070459)
0.9	9.4	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.9	8.4	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.9	40.6	GO:0035036	sperm-egg recognition(GO:0035036)
0.9	21.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.9	2.7	GO:1990535	neuron projection maintenance(GO:1990535)
0.9	6.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.9	8.8	GO:0015889	cobalamin transport(GO:0015889)
0.9	1.7	GO:0070827	chromatin maintenance(GO:0070827)
0.8	4.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.8	3.4	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.8	7.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.8	6.7	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.8	1.7	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.8	7.4	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.8	9.8	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.8	3.2	GO:0042182	ketone catabolic process(GO:0042182)
0.8	2.4	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.8	8.7	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.8	6.4	GO:0006836	neurotransmitter transport(GO:0006836)
0.8	14.2	GO:0010002	cardioblast differentiation(GO:0010002)
0.8	29.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.8	6.3	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8	12.5	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.8	14.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.8	2.3	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.8	3.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.8	1.5	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.8	3.8	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.8	18.9	GO:0007628	adult walking behavior(GO:0007628)
0.8	16.5	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.7	45.7	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.7	8.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7	2.2	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.7	4.5	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.7	5.2	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.7	3.0	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.7	20.7	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.7	0.7	GO:0060157	urinary bladder development(GO:0060157)
0.7	3.7	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.7	2.2	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
0.7	2.9	GO:0010587	miRNA catabolic process(GO:0010587)
0.7	2.2	GO:0060174	limb bud formation(GO:0060174)
0.7	15.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.7	10.7	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.7	8.6	GO:0030238	male sex determination(GO:0030238)
0.7	2.8	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.7	2.1	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.7	2.1	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.7	0.7	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.7	26.9	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.7	2.7	GO:0042412	taurine biosynthetic process(GO:0042412)
0.7	68.0	GO:0007286	spermatid development(GO:0007286)
0.7	8.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.7	2.0	GO:0035936	testosterone secretion(GO:0035936) regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.6	1.9	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.6	5.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.6	14.1	GO:0006895	Golgi to endosome transport(GO:0006895)
0.6	9.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.6	4.5	GO:0060068	vagina development(GO:0060068)
0.6	2.5	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.6	12.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6	5.0	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6	1.9	GO:0034756	regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.6	1.9	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.6	1.8	GO:0072396	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.6	11.0	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.6	7.3	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.6	4.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.6	3.0	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.6	4.8	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6	15.7	GO:0097178	ruffle assembly(GO:0097178)
0.6	5.4	GO:0006069	ethanol oxidation(GO:0006069)
0.6	4.2	GO:0070375	ERK5 cascade(GO:0070375)
0.6	13.8	GO:0016578	histone deubiquitination(GO:0016578)
0.6	3.0	GO:0016236	macroautophagy(GO:0016236)
0.6	4.8	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.6	12.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.6	2.4	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.6	10.6	GO:0060736	prostate gland growth(GO:0060736)
0.6	1.8	GO:0070781	response to biotin(GO:0070781)
0.6	2.3	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.6	6.4	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.6	8.1	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.6	2.3	GO:0042631	cellular response to water deprivation(GO:0042631)
0.6	2.3	GO:1990403	embryonic brain development(GO:1990403)
0.6	20.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.6	1.7	GO:0060718	negative regulation of cytokinesis(GO:0032466) chorionic trophoblast cell differentiation(GO:0060718)
0.6	3.4	GO:1903760	regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.6	3.4	GO:0035799	ureter maturation(GO:0035799)
0.6	1.1	GO:1902623	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.6	2.2	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031) positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.6	39.3	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.6	1.1	GO:0060290	transdifferentiation(GO:0060290)
0.5	2.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.5	1.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.5	2.2	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.5	2.2	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.5	9.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.5	1.6	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.5	3.8	GO:0001661	conditioned taste aversion(GO:0001661)
0.5	1.6	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.5	8.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.5	1.6	GO:0015729	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.5	13.9	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.5	2.0	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.5	3.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.5	11.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.5	7.6	GO:0015671	oxygen transport(GO:0015671)
0.5	1.0	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.5	11.5	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.5	36.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.5	10.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.5	4.4	GO:0048820	hair follicle maturation(GO:0048820)
0.5	1.9	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.5	25.9	GO:0071277	cellular response to calcium ion(GO:0071277)
0.5	3.3	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.5	2.9	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.5	17.0	GO:0014047	glutamate secretion(GO:0014047)
0.5	2.3	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.5	11.8	GO:0097503	sialylation(GO:0097503)
0.5	5.0	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5	3.6	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.4	4.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.4	8.9	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4	1.3	GO:0061333	renal tubule morphogenesis(GO:0061333) nephron epithelium development(GO:0072009) nephron morphogenesis(GO:0072028)
0.4	16.9	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.4	1.8	GO:0043473	pigmentation(GO:0043473)
0.4	11.4	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.4	1.7	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.4	8.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	14.0	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.4	6.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.4	28.2	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.4	6.7	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.4	1.3	GO:0021553	olfactory nerve development(GO:0021553)
0.4	2.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.4	13.5	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4	7.4	GO:0050919	negative chemotaxis(GO:0050919)
0.4	5.7	GO:0001935	endothelial cell proliferation(GO:0001935)
0.4	1.6	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.4	2.5	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.4	2.9	GO:0042426	choline catabolic process(GO:0042426)
0.4	4.9	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4	5.7	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4	4.0	GO:0042634	regulation of hair cycle(GO:0042634)
0.4	5.9	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.4	1.5	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.4	7.6	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.4	7.6	GO:0071420	cellular response to histamine(GO:0071420)
0.4	2.3	GO:0043366	beta selection(GO:0043366)
0.4	1.5	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.4	2.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.4	3.7	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.4	26.8	GO:0042795	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.4	3.7	GO:0035330	regulation of hippo signaling(GO:0035330)
0.4	4.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.4	5.8	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.4	17.0	GO:0048477	oogenesis(GO:0048477)
0.4	2.1	GO:0018343	protein farnesylation(GO:0018343)
0.4	14.8	GO:0042073	intraciliary transport(GO:0042073)
0.4	2.5	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.4	3.5	GO:0099612	protein localization to axon(GO:0099612)
0.3	8.7	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.3	11.8	GO:0030279	negative regulation of ossification(GO:0030279)
0.3	6.5	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.3	1.4	GO:0071630	trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3	6.5	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.3	0.7	GO:0043132	NAD transport(GO:0043132)
0.3	1.0	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.3	3.9	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3	4.2	GO:0036376	sodium ion export from cell(GO:0036376)
0.3	7.4	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.3	6.7	GO:0030488	tRNA methylation(GO:0030488)
0.3	5.5	GO:0032210	regulation of telomere maintenance via telomerase(GO:0032210)
0.3	0.6	GO:0060574	columnar/cuboidal epithelial cell maturation(GO:0002069) intestinal epithelial cell maturation(GO:0060574)
0.3	0.9	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.3	1.6	GO:1901160	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.3	9.0	GO:0009081	branched-chain amino acid metabolic process(GO:0009081)
0.3	0.3	GO:1903416	response to glycoside(GO:1903416)
0.3	5.8	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.3	4.3	GO:0008340	determination of adult lifespan(GO:0008340)
0.3	4.0	GO:0009584	detection of visible light(GO:0009584)
0.3	6.1	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.3	13.6	GO:1903146	regulation of mitophagy(GO:1903146)
0.3	1.2	GO:0030432	peristalsis(GO:0030432)
0.3	3.0	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.3	1.5	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.3	1.8	GO:0051597	response to methylmercury(GO:0051597)
0.3	1.5	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3	6.9	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.3	0.6	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of neurotransmitter transport(GO:0051590) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3	0.6	GO:0060324	face development(GO:0060324)
0.3	11.0	GO:0043966	histone H3 acetylation(GO:0043966)
0.3	5.0	GO:1900115	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	5.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3	14.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3	4.5	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.3	3.2	GO:0030509	BMP signaling pathway(GO:0030509)
0.3	13.9	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.3	2.6	GO:0030308	negative regulation of cell growth(GO:0030308)
0.3	1.6	GO:0008343	adult feeding behavior(GO:0008343)
0.3	1.5	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.3	3.1	GO:0048265	response to pain(GO:0048265)
0.3	1.3	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.2	10.7	GO:0030500	regulation of bone mineralization(GO:0030500)
0.2	2.7	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2	2.2	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.2	3.6	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2	2.4	GO:0001553	luteinization(GO:0001553)
0.2	3.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.2	1.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2	4.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.2	9.9	GO:0006513	protein monoubiquitination(GO:0006513)
0.2	4.8	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.2	5.9	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.2	2.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2	1.3	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.2	3.7	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.2	4.5	GO:0005979	regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2	3.6	GO:0001502	cartilage condensation(GO:0001502)
0.2	5.3	GO:0007520	myoblast fusion(GO:0007520)
0.2	5.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2	5.5	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.2	2.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	8.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.2	0.8	GO:0000076	DNA replication checkpoint(GO:0000076)
0.2	4.3	GO:0070987	error-free translesion synthesis(GO:0070987)
0.2	0.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2	4.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.2	2.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.2	0.4	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.2	4.1	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.2	2.3	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.2	2.3	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.2	10.1	GO:0019233	sensory perception of pain(GO:0019233)
0.2	32.4	GO:0007601	visual perception(GO:0007601)
0.2	1.3	GO:0044266	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.2	2.0	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.2	18.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.2	8.6	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.2	4.3	GO:0072337	modified amino acid transport(GO:0072337)
0.2	0.5	GO:0019448	cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.2	0.7	GO:0045003	meiotic DNA recombinase assembly(GO:0000707) DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2	3.5	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.2	3.6	GO:0006400	tRNA modification(GO:0006400)
0.2	12.6	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	2.4	GO:0060384	innervation(GO:0060384)
0.2	1.2	GO:0016322	neuron remodeling(GO:0016322)
0.2	2.4	GO:0018345	protein palmitoylation(GO:0018345)
0.2	1.6	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.2	1.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2	1.9	GO:0006681	galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.2	0.5	GO:0018298	protein-chromophore linkage(GO:0018298)
0.2	2.5	GO:0042359	vitamin D metabolic process(GO:0042359)
0.2	3.1	GO:0031648	protein destabilization(GO:0031648)
0.2	2.3	GO:0048483	autonomic nervous system development(GO:0048483)
0.2	0.3	GO:0035814	negative regulation of urine volume(GO:0035811) negative regulation of renal sodium excretion(GO:0035814)
0.1	1.8	GO:0007097	nuclear migration(GO:0007097)
0.1	2.0	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.1	1.6	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.1	1.7	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	1.4	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	5.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.4	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.1	GO:0072708	response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709)
0.1	1.9	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.1	0.6	GO:0015791	polyol transport(GO:0015791)
0.1	0.9	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1	0.9	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	1.7	GO:0042737	drug catabolic process(GO:0042737)
0.1	0.5	GO:0071389	cellular response to corticosterone stimulus(GO:0071386) cellular response to mineralocorticoid stimulus(GO:0071389)
0.1	2.5	GO:0009880	embryonic pattern specification(GO:0009880)
0.1	1.2	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	65.7	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.1	2.0	GO:0043030	regulation of macrophage activation(GO:0043030)
0.1	1.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	3.0	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	3.2	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	4.1	GO:0015701	bicarbonate transport(GO:0015701)
0.1	0.3	GO:1990173	establishment of protein localization to telomere(GO:0070200) regulation of establishment of protein localization to telomere(GO:0070203) scaRNA localization to Cajal body(GO:0090666) protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1	1.8	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1	2.7	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.3	GO:0002024	diet induced thermogenesis(GO:0002024)
0.1	2.2	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.7	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.1	1.1	GO:0032196	transposition(GO:0032196)
0.1	5.9	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	1.5	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.1	1.3	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	0.8	GO:0015074	DNA integration(GO:0015074)
0.1	0.5	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	1.0	GO:0042552	myelination(GO:0042552)
0.1	0.5	GO:0007266	Rho protein signal transduction(GO:0007266)
0.1	2.8	GO:0015804	neutral amino acid transport(GO:0015804)
0.1	0.3	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1	1.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	1.6	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	1.6	GO:1904029	regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1	0.4	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1	0.7	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1	1.6	GO:1901998	toxin transport(GO:1901998)
0.1	1.6	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.9	GO:0030220	platelet formation(GO:0030220)
0.1	1.3	GO:0007088	regulation of mitotic nuclear division(GO:0007088)
0.1	0.7	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1	0.3	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892) cerebral cortex GABAergic interneuron development(GO:0021894)
0.1	1.2	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1	0.9	GO:0070849	response to epidermal growth factor(GO:0070849)
0.1	0.8	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	10.8	GO:0006470	protein dephosphorylation(GO:0006470)
0.1	0.1	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.0	1.6	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	2.7	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	1.0	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	23.7	GO:0016567	protein ubiquitination(GO:0016567)
0.0	0.3	GO:0032264	IMP salvage(GO:0032264)
0.0	2.2	GO:0055072	iron ion homeostasis(GO:0055072)
0.0	0.9	GO:0030282	bone mineralization(GO:0030282)
0.0	0.8	GO:0002223	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.2	GO:0003341	cilium movement(GO:0003341)
0.0	0.5	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.5	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.7	GO:0030819	positive regulation of cAMP biosynthetic process(GO:0030819)
0.0	0.2	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.6	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	1.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.7	38.8	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
9.5	28.6	GO:0043198	dendritic shaft(GO:0043198)
9.2	36.9	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
8.6	42.9	GO:0071546	pi-body(GO:0071546)
8.5	67.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
8.3	66.7	GO:0033391	chromatoid body(GO:0033391)
7.0	7.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
6.3	75.7	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
6.0	23.8	GO:0033596	TSC1-TSC2 complex(GO:0033596)
4.7	23.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
4.2	16.8	GO:0044611	nuclear pore inner ring(GO:0044611)
4.2	16.8	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
4.1	24.6	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
3.9	51.2	GO:0030897	HOPS complex(GO:0030897)
3.8	11.5	GO:0019034	viral replication complex(GO:0019034)
3.8	19.2	GO:0033263	CORVET complex(GO:0033263)
3.7	14.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
3.7	11.0	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
3.5	13.9	GO:0030896	checkpoint clamp complex(GO:0030896)
3.3	10.0	GO:0044305	calyx of Held(GO:0044305)
3.3	13.3	GO:0000333	telomerase catalytic core complex(GO:0000333)
3.3	19.9	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
3.2	16.2	GO:0089701	U2AF(GO:0089701)
3.2	22.4	GO:0044326	dendritic spine neck(GO:0044326)
3.1	101.0	GO:0000795	synaptonemal complex(GO:0000795)
2.8	13.8	GO:0070847	core mediator complex(GO:0070847)
2.7	5.4	GO:0030132	clathrin coat of coated pit(GO:0030132)
2.6	23.6	GO:0005827	polar microtubule(GO:0005827)
2.6	43.9	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
2.6	20.5	GO:0036157	outer dynein arm(GO:0036157)
2.5	17.3	GO:0035371	microtubule plus-end(GO:0035371)
2.5	41.9	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
2.3	23.3	GO:0097433	dense body(GO:0097433)
2.3	11.6	GO:0044308	axonal spine(GO:0044308)
2.3	6.9	GO:0098536	deuterosome(GO:0098536)
2.3	11.3	GO:0044530	supraspliceosomal complex(GO:0044530)
2.2	13.3	GO:0032444	activin responsive factor complex(GO:0032444)
2.1	8.5	GO:0035838	growing cell tip(GO:0035838)
2.1	14.6	GO:0072487	MSL complex(GO:0072487)
2.0	14.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.9	5.8	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
1.9	13.5	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
1.9	3.7	GO:0043527	tRNA methyltransferase complex(GO:0043527)
1.8	12.7	GO:0001520	outer dense fiber(GO:0001520)
1.8	22.9	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.7	5.2	GO:0000439	core TFIIH complex(GO:0000439)
1.7	32.5	GO:0097225	sperm midpiece(GO:0097225)
1.7	11.8	GO:1990635	proximal dendrite(GO:1990635)
1.7	90.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
1.6	7.9	GO:0032389	MutLalpha complex(GO:0032389)
1.6	25.1	GO:0031045	dense core granule(GO:0031045)
1.6	1.6	GO:1990769	proximal neuron projection(GO:1990769)
1.6	18.7	GO:0043203	axon hillock(GO:0043203)
1.5	4.5	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.4	9.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
1.4	38.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
1.3	7.9	GO:0032010	phagolysosome(GO:0032010)
1.3	9.1	GO:0097452	GAIT complex(GO:0097452)
1.3	8.8	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
1.2	30.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.2	1.2	GO:0036020	endolysosome membrane(GO:0036020)
1.2	5.8	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
1.1	9.0	GO:0044294	dendritic growth cone(GO:0044294)
1.1	20.0	GO:0005922	connexon complex(GO:0005922)
1.1	2.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
1.1	19.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
1.0	10.3	GO:0070938	contractile ring(GO:0070938)
1.0	5.9	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.0	8.6	GO:0042788	polysomal ribosome(GO:0042788)
0.9	10.2	GO:0000243	commitment complex(GO:0000243)
0.9	7.4	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.9	4.6	GO:0036128	CatSper complex(GO:0036128)
0.9	15.4	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.9	8.0	GO:0032039	integrator complex(GO:0032039)
0.9	43.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.8	3.3	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.8	5.8	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.8	14.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.8	20.9	GO:0005721	pericentric heterochromatin(GO:0005721)
0.8	11.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.7	37.0	GO:0016235	aggresome(GO:0016235)
0.7	41.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7	18.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.7	3.3	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.7	15.3	GO:0031143	pseudopodium(GO:0031143)
0.7	13.1	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.7	5.9	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.6	10.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.6	3.7	GO:0030991	intraciliary transport particle A(GO:0030991)
0.6	6.2	GO:0042587	glycogen granule(GO:0042587)
0.6	3.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.6	4.1	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.6	5.9	GO:0044327	dendritic spine head(GO:0044327)
0.6	2.9	GO:0033553	rDNA heterochromatin(GO:0033553)
0.6	13.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.5	8.8	GO:0016461	unconventional myosin complex(GO:0016461)
0.5	4.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.5	1.0	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.5	15.0	GO:0031527	filopodium membrane(GO:0031527)
0.5	13.9	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.5	8.3	GO:0043235	receptor complex(GO:0043235)
0.5	4.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.5	6.7	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.5	12.9	GO:0002080	acrosomal membrane(GO:0002080)
0.5	3.8	GO:0035976	AP1 complex(GO:0035976)
0.5	1.9	GO:0045179	apical cortex(GO:0045179)
0.5	50.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.5	3.7	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.5	1.8	GO:0043293	apoptosome(GO:0043293)
0.4	10.8	GO:0030131	clathrin adaptor complex(GO:0030131)
0.4	45.7	GO:0005814	centriole(GO:0005814)
0.4	2.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4	7.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4	6.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.4	12.7	GO:0016592	mediator complex(GO:0016592)
0.4	12.7	GO:0042101	T cell receptor complex(GO:0042101)
0.4	15.5	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.4	3.5	GO:0060077	inhibitory synapse(GO:0060077)
0.4	13.8	GO:0009925	basal plasma membrane(GO:0009925)
0.4	1.8	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.4	13.0	GO:0048786	presynaptic active zone(GO:0048786)
0.4	10.5	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.3	1.4	GO:0032279	asymmetric synapse(GO:0032279)
0.3	5.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.3	25.0	GO:0016459	myosin complex(GO:0016459)
0.3	0.7	GO:0032593	insulin-responsive compartment(GO:0032593)
0.3	9.6	GO:0032590	dendrite membrane(GO:0032590)
0.3	3.4	GO:0033268	node of Ranvier(GO:0033268)
0.3	44.5	GO:0055037	recycling endosome(GO:0055037)
0.3	6.9	GO:0044306	neuron projection terminus(GO:0044306)
0.3	1.8	GO:0061617	MICOS complex(GO:0061617)
0.3	18.7	GO:0005802	trans-Golgi network(GO:0005802)
0.3	16.8	GO:0030175	filopodium(GO:0030175)
0.3	14.2	GO:0005801	cis-Golgi network(GO:0005801)
0.3	3.0	GO:0043083	synaptic cleft(GO:0043083)
0.3	3.2	GO:0031082	BLOC complex(GO:0031082)
0.3	0.8	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3	0.8	GO:0070876	SOSS complex(GO:0070876)
0.2	5.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	14.8	GO:0005770	late endosome(GO:0005770)
0.2	1.4	GO:0043196	varicosity(GO:0043196)
0.2	4.5	GO:0097546	ciliary base(GO:0097546)
0.2	7.7	GO:0030315	T-tubule(GO:0030315)
0.2	1.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	10.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.2	0.9	GO:0097512	cardiac myofibril(GO:0097512)
0.2	2.4	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	9.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.2	1.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.2	3.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	43.4	GO:0001726	ruffle(GO:0001726)
0.2	2.9	GO:0005652	nuclear lamina(GO:0005652)
0.2	2.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	13.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	4.8	GO:0005929	cilium(GO:0005929)
0.2	1.8	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2	129.7	GO:0045202	synapse(GO:0045202)
0.2	2.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	4.8	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	1.9	GO:0044447	axoneme part(GO:0044447)
0.2	0.9	GO:0030056	hemidesmosome(GO:0030056)
0.2	1.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	9.9	GO:0034707	chloride channel complex(GO:0034707)
0.2	2.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.2	2.2	GO:0034451	centriolar satellite(GO:0034451)
0.2	4.9	GO:0070461	SAGA-type complex(GO:0070461)
0.2	16.5	GO:0005903	brush border(GO:0005903)
0.2	1.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	1.8	GO:0002116	semaphorin receptor complex(GO:0002116)
0.2	14.8	GO:0031514	motile cilium(GO:0031514)
0.2	38.4	GO:0045121	membrane raft(GO:0045121)
0.1	1.5	GO:0097427	microtubule bundle(GO:0097427)
0.1	16.0	GO:0031225	anchored component of membrane(GO:0031225)
0.1	4.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.7	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	2.8	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	4.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	2.3	GO:0036064	ciliary basal body(GO:0036064)
0.1	0.7	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	2.0	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.1	14.5	GO:0034399	nuclear periphery(GO:0034399)
0.1	21.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	2.5	GO:0005795	Golgi stack(GO:0005795)
0.1	1.0	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	3.6	GO:0042383	sarcolemma(GO:0042383)
0.1	2.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	4.9	GO:0043204	perikaryon(GO:0043204)
0.1	2.0	GO:0005796	Golgi lumen(GO:0005796)
0.1	2.2	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	2.1	GO:0005682	U5 snRNP(GO:0005682)
0.1	1.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	10.5	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	0.3	GO:0000346	transcription export complex(GO:0000346)
0.1	4.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	27.0	GO:0016607	nuclear speck(GO:0016607)
0.1	14.6	GO:0043025	neuronal cell body(GO:0043025)
0.1	0.4	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	24.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	2.4	GO:0030424	axon(GO:0030424)
0.1	2.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	27.8	GO:0005815	microtubule organizing center(GO:0005815)
0.1	4.0	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	3.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	4.3	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	0.7	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.1	0.9	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.9	GO:0005876	spindle microtubule(GO:0005876)
0.0	1.8	GO:0016324	apical plasma membrane(GO:0016324)
0.0	2.2	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.7	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	1.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.6	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	65.6	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
26.5	132.6	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
15.9	63.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
13.1	39.3	GO:0015439	heme-transporting ATPase activity(GO:0015439)
11.5	68.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
10.1	30.2	GO:0004802	transketolase activity(GO:0004802)
9.7	29.0	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
9.2	36.9	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
8.8	96.9	GO:0031681	G-protein beta-subunit binding(GO:0031681)
7.9	23.8	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
7.8	23.4	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
7.6	167.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
7.5	22.6	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
6.8	20.5	GO:0034584	piRNA binding(GO:0034584)
6.8	27.3	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
6.1	18.3	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
6.0	48.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
5.7	17.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
5.7	17.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
5.6	16.8	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
5.2	15.6	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
4.7	19.0	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
4.7	14.1	GO:0019961	interferon binding(GO:0019961)
4.6	23.0	GO:0070097	delta-catenin binding(GO:0070097)
4.4	39.3	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
4.3	25.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
4.2	16.7	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
4.1	24.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
4.0	12.0	GO:0004103	choline kinase activity(GO:0004103)
3.8	11.5	GO:0005137	interleukin-5 receptor binding(GO:0005137)
3.8	11.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
3.8	11.4	GO:0035033	histone deacetylase regulator activity(GO:0035033)
3.7	58.9	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.7	11.0	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
3.6	7.2	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
3.5	10.6	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
3.5	17.5	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
3.5	27.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
3.4	20.7	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
3.4	20.5	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.4	10.2	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
3.3	9.8	GO:0061663	NEDD8 ligase activity(GO:0061663)
3.2	16.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
3.2	9.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
3.2	9.6	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
3.2	28.6	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
3.1	24.7	GO:0004565	beta-galactosidase activity(GO:0004565)
3.1	30.8	GO:0009374	biotin binding(GO:0009374)
3.1	12.3	GO:0035939	microsatellite binding(GO:0035939)
2.9	11.7	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
2.9	8.8	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.9	31.7	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.8	13.8	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.7	8.2	GO:0098770	FBXO family protein binding(GO:0098770)
2.7	8.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
2.7	13.5	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
2.7	8.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
2.7	26.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
2.7	8.0	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
2.7	10.6	GO:0031685	adenosine receptor binding(GO:0031685)
2.7	10.6	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
2.6	12.9	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
2.5	4.9	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
2.5	4.9	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
2.5	9.8	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.4	7.3	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
2.4	40.8	GO:0019992	diacylglycerol binding(GO:0019992)
2.3	30.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
2.3	13.9	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
2.3	32.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
2.2	60.4	GO:0005326	neurotransmitter transporter activity(GO:0005326)
2.1	10.7	GO:0061665	SUMO ligase activity(GO:0061665)
2.1	27.3	GO:0031005	filamin binding(GO:0031005)
2.0	8.1	GO:0004461	lactose synthase activity(GO:0004461)
2.0	4.0	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
2.0	3.9	GO:0070888	E-box binding(GO:0070888)
2.0	19.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.9	9.7	GO:0031893	vasopressin receptor binding(GO:0031893)
1.9	9.6	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.9	5.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.9	5.6	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.8	29.2	GO:0097109	neuroligin family protein binding(GO:0097109)
1.8	29.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
1.8	9.0	GO:0097108	hedgehog family protein binding(GO:0097108)
1.8	25.2	GO:0008179	adenylate cyclase binding(GO:0008179)
1.8	7.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.8	7.0	GO:0019770	IgG receptor activity(GO:0019770)
1.7	7.0	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.7	3.5	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
1.7	24.4	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
1.7	5.2	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.7	24.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.7	5.0	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
1.7	8.4	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
1.7	6.7	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.7	18.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
1.7	8.4	GO:0052844	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.6	16.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.6	4.8	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.6	64.5	GO:0017025	TBP-class protein binding(GO:0017025)
1.5	15.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
1.5	18.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
1.5	3.0	GO:0032767	copper-dependent protein binding(GO:0032767)
1.5	4.5	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.5	7.5	GO:0004995	tachykinin receptor activity(GO:0004995)
1.5	4.5	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
1.5	17.8	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.5	25.1	GO:0015250	water channel activity(GO:0015250)
1.4	8.6	GO:0032407	MutSalpha complex binding(GO:0032407)
1.4	4.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.4	6.9	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
1.4	11.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
1.4	39.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.3	30.9	GO:0004383	guanylate cyclase activity(GO:0004383)
1.3	8.0	GO:0004473	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.3	18.7	GO:0004065	arylsulfatase activity(GO:0004065)
1.3	8.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
1.2	13.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.2	37.2	GO:0017075	syntaxin-1 binding(GO:0017075)
1.2	4.9	GO:0008384	IkappaB kinase activity(GO:0008384)
1.2	34.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
1.2	9.5	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.2	4.7	GO:0070087	chromo shadow domain binding(GO:0070087)
1.1	5.7	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
1.1	28.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.1	3.3	GO:1904288	BAT3 complex binding(GO:1904288)
1.1	40.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
1.1	4.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
1.1	2.2	GO:0034511	U3 snoRNA binding(GO:0034511)
1.1	2.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
1.1	20.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
1.1	3.2	GO:0070538	oleic acid binding(GO:0070538)
1.1	12.7	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
1.0	10.4	GO:0005243	gap junction channel activity(GO:0005243)
1.0	20.5	GO:0045504	dynein heavy chain binding(GO:0045504)
1.0	11.1	GO:0051525	NFAT protein binding(GO:0051525)
1.0	5.0	GO:0008420	CTD phosphatase activity(GO:0008420)
1.0	4.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.0	5.8	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.0	8.7	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
1.0	2.9	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
1.0	3.8	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.0	4.8	GO:0008174	mRNA methyltransferase activity(GO:0008174)
1.0	2.9	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.9	10.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.9	5.6	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.9	31.3	GO:0070840	dynein complex binding(GO:0070840)
0.9	33.0	GO:0005109	frizzled binding(GO:0005109)
0.9	3.7	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.9	13.5	GO:0015643	toxic substance binding(GO:0015643)
0.9	48.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.9	11.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.9	15.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.9	3.5	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.9	17.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.9	14.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.8	2.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.8	2.5	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.8	10.8	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.8	55.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.8	29.8	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.8	79.0	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.8	15.9	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.7	13.5	GO:0005522	profilin binding(GO:0005522)
0.7	2.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.7	3.0	GO:0004104	acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.7	8.9	GO:0051219	phosphoprotein binding(GO:0051219)
0.7	1.5	GO:1990763	arrestin family protein binding(GO:1990763)
0.7	5.7	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.7	2.9	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.7	1.4	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.7	9.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.7	15.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.7	11.0	GO:0042923	neuropeptide binding(GO:0042923)
0.7	11.6	GO:0004659	prenyltransferase activity(GO:0004659)
0.7	2.7	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.7	2.7	GO:0043559	insulin binding(GO:0043559)
0.6	2.6	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6	8.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6	12.1	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.6	0.6	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.6	2.5	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.6	3.8	GO:0030983	mismatched DNA binding(GO:0030983)
0.6	1.9	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.6	2.5	GO:0016361	activin receptor activity, type I(GO:0016361)
0.6	1.8	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.6	3.0	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.6	7.7	GO:0031432	titin binding(GO:0031432)
0.6	3.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.6	5.9	GO:0043495	protein anchor(GO:0043495)
0.6	2.9	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.6	18.8	GO:0015248	sterol transporter activity(GO:0015248)
0.6	6.4	GO:0051434	BH3 domain binding(GO:0051434)
0.6	7.6	GO:0005344	oxygen transporter activity(GO:0005344)
0.6	21.9	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.6	3.4	GO:0045499	chemorepellent activity(GO:0045499)
0.6	4.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.5	2.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.5	2.2	GO:0071253	connexin binding(GO:0071253)
0.5	1.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5	9.5	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.5	1.6	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.5	3.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.5	11.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.5	15.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.5	4.2	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.5	23.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.5	14.0	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.5	12.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	32.7	GO:0035064	methylated histone binding(GO:0035064)
0.5	12.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.5	5.9	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.5	4.9	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5	11.6	GO:0005521	lamin binding(GO:0005521)
0.5	10.0	GO:0032451	demethylase activity(GO:0032451)
0.5	3.3	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.5	7.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	1.4	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.5	11.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.5	4.5	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.5	3.6	GO:0034235	GPI anchor binding(GO:0034235)
0.4	11.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.4	5.3	GO:0019864	IgG binding(GO:0019864)
0.4	19.0	GO:0042162	telomeric DNA binding(GO:0042162)
0.4	18.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.4	6.5	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.4	2.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.4	28.7	GO:0019905	syntaxin binding(GO:0019905)
0.4	1.3	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.4	14.9	GO:0070412	R-SMAD binding(GO:0070412)
0.4	100.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.4	4.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.4	2.9	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.4	4.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.4	8.0	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.4	23.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.4	2.4	GO:0003696	satellite DNA binding(GO:0003696)
0.4	1.6	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.4	3.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.4	1.1	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.4	2.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.4	1.1	GO:0070728	leucine binding(GO:0070728)
0.4	4.0	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.3	141.7	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3	1.4	GO:0043426	MRF binding(GO:0043426)
0.3	2.4	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.3	3.7	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3	7.0	GO:0008066	glutamate receptor activity(GO:0008066)
0.3	1.7	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3	3.0	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.3	8.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	1.9	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.3	8.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	3.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.3	2.2	GO:0034452	dynactin binding(GO:0034452)
0.3	3.4	GO:0097016	L27 domain binding(GO:0097016)
0.3	2.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.3	3.6	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.3	3.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.3	13.1	GO:0030507	spectrin binding(GO:0030507)
0.3	6.8	GO:0042169	SH2 domain binding(GO:0042169)
0.3	1.2	GO:0004977	melanocortin receptor activity(GO:0004977)
0.3	5.8	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.3	11.7	GO:0003785	actin monomer binding(GO:0003785)
0.3	7.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.3	18.0	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.3	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.3	2.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.3	0.8	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3	4.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.3	9.9	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3	4.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.3	33.6	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3	3.0	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2	4.7	GO:0051184	cofactor transporter activity(GO:0051184)
0.2	2.7	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.2	1.9	GO:0010181	FMN binding(GO:0010181)
0.2	5.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.2	36.0	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2	0.9	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	25.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	13.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.2	71.3	GO:0005096	GTPase activator activity(GO:0005096)
0.2	21.4	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.2	3.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	42.4	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.2	8.4	GO:0030552	cAMP binding(GO:0030552)
0.2	4.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.2	1.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2	8.4	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.2	1.0	GO:0004368	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2	8.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	4.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2	5.0	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2	2.2	GO:0070700	BMP receptor binding(GO:0070700)
0.2	4.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.2	0.5	GO:1904047	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) S-adenosyl-L-methionine binding(GO:1904047)
0.2	3.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.2	1.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2	4.6	GO:0000217	DNA secondary structure binding(GO:0000217)
0.2	3.4	GO:0050811	GABA receptor binding(GO:0050811)
0.2	18.8	GO:0004896	cytokine receptor activity(GO:0004896)
0.2	1.8	GO:0043531	ADP binding(GO:0043531)
0.2	8.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.2	2.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2	2.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	1.9	GO:0019957	C-C chemokine binding(GO:0019957)
0.2	5.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.2	5.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2	16.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.2	39.9	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	1.3	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	1.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	2.9	GO:0051018	protein kinase A binding(GO:0051018)
0.1	2.0	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	2.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	4.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	1.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	2.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	2.9	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	1.2	GO:0030882	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1	0.4	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.9	GO:0038132	neuregulin binding(GO:0038132)
0.1	2.7	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	2.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.9	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	2.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	7.9	GO:0005179	hormone activity(GO:0005179)
0.1	8.4	GO:0019902	phosphatase binding(GO:0019902)
0.1	1.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.9	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	0.4	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.6	GO:0004952	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine neurotransmitter receptor activity(GO:0004952)
0.1	2.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	3.2	GO:0030165	PDZ domain binding(GO:0030165)
0.1	2.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	5.2	GO:0001618	virus receptor activity(GO:0001618)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	3.8	GO:0043130	ubiquitin binding(GO:0043130)
0.1	1.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.5	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.6	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.9	GO:0005272	sodium channel activity(GO:0005272)
0.0	1.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.8	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.7	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	1.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.3	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	2.0	GO:0005506	iron ion binding(GO:0005506)
0.0	0.3	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.5	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.2	GO:0016918	retinal binding(GO:0016918)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	1.5	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	56.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
1.3	44.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.2	8.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
1.2	30.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
1.1	61.9	PID AURORA A PATHWAY	Aurora A signaling
1.1	50.3	PID REELIN PATHWAY	Reelin signaling pathway
1.0	24.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.0	14.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.9	14.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.9	19.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.9	24.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.9	16.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.9	12.9	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.8	7.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.7	7.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.7	9.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.7	19.0	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.6	11.9	PID ALK2 PATHWAY	ALK2 signaling events
0.6	25.6	PID RAS PATHWAY	Regulation of Ras family activation
0.6	25.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.6	11.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.5	13.4	PID EPHB FWD PATHWAY	EPHB forward signaling
0.5	8.6	ST GAQ PATHWAY	G alpha q Pathway
0.5	11.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.5	19.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.5	10.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.5	8.8	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.5	12.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	3.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4	23.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.4	8.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	3.8	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4	4.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4	33.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.3	3.8	ST GA12 PATHWAY	G alpha 12 Pathway
0.3	14.9	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.3	8.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	17.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.3	3.2	PID EPO PATHWAY	EPO signaling pathway
0.3	34.8	PID P73PATHWAY	p73 transcription factor network
0.3	17.4	PID PLK1 PATHWAY	PLK1 signaling events
0.3	6.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	4.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	12.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.2	3.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.2	12.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	3.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.2	11.5	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	2.7	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.2	11.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	11.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.2	3.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	7.0	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2	5.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	3.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	14.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	8.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	4.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	4.5	PID FGF PATHWAY	FGF signaling pathway
0.1	2.5	PID ARF 3PATHWAY	Arf1 pathway
0.1	1.9	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	5.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	2.5	PID FOXO PATHWAY	FoxO family signaling
0.1	4.5	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	4.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	3.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	1.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	2.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	2.7	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	0.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	2.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.9	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	2.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	11.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	3.2	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.0	101.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.4	4.8	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
2.0	76.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
1.9	28.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.8	43.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.8	25.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.8	24.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.6	73.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.6	44.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
1.6	18.7	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.5	32.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.5	32.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.4	29.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
1.3	31.4	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
1.3	25.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
1.3	66.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.3	13.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
1.2	10.5	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.2	17.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
1.1	21.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
1.1	20.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
1.1	74.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
1.0	51.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
1.0	14.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.9	6.4	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.9	2.7	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.9	23.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.9	13.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.8	74.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.8	9.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8	13.6	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.7	24.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.7	16.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.7	11.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.7	8.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.7	5.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.7	12.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.7	10.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.7	19.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.6	14.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6	12.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.6	12.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.6	46.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.6	5.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.6	11.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6	11.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6	14.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.6	7.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.5	6.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.5	6.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.5	11.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.5	44.9	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.5	8.9	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.5	26.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.5	1.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.5	11.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.5	13.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.5	105.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.5	14.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.4	4.9	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.4	9.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.4	4.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	6.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.4	13.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.4	36.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.4	4.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.4	8.9	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.4	18.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.4	3.0	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.4	8.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4	7.7	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.3	11.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.3	3.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.3	8.0	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.3	2.6	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.3	7.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.3	13.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.3	9.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.3	11.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.3	2.9	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.3	1.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.3	16.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	4.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	6.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.3	26.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.3	11.9	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.3	11.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.3	2.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.3	3.6	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.3	4.7	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.3	12.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	5.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.2	4.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	3.1	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.2	1.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	17.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.2	3.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.2	10.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	3.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	3.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	2.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	2.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	2.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	4.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	2.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	0.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	12.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.0	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.7	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling

Results for MNT_HEY1_HEY2

Z-value: 1.05

Motif logo

Transcription factors associated with MNT_HEY1_HEY2

Activity-expression correlation:

Activity profile of MNT_HEY1_HEY2 motif

Sorted Z-values of MNT_HEY1_HEY2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MNT_HEY1_HEY2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: