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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for MXI1_MYC_MYCN
Z-value: 1.99
Motif logo
Transcription factors associated with MXI1_MYC_MYCN
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MXI1
|
ENSG00000119950.16 | MAX interactor 1, dimerization protein |
|
MYC
|
ENSG00000136997.10 | MYC proto-oncogene, bHLH transcription factor |
|
MYCN
|
ENSG00000134323.10 | MYCN proto-oncogene, bHLH transcription factor |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYC | hg19_v2_chr8_+_128748466_128748487, hg19_v2_chr8_+_128748308_128748330 | 0.79 | 7.1e-48 | Click! |
| MYCN | hg19_v2_chr2_+_16080659_16080686 | -0.63 | 1.8e-25 | Click! |
| MXI1 | hg19_v2_chr10_+_111985713_111985774, hg19_v2_chr10_+_111967345_111967442 | -0.34 | 1.9e-07 | Click! |
Activity profile of MXI1_MYC_MYCN motif
Sorted Z-values of MXI1_MYC_MYCN motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_58146128 | 239.34 |
ENST00000551800.1
ENST00000549606.1 ENST00000257904.6 |
CDK4
|
cyclin-dependent kinase 4 |
| chr12_-_58146048 | 238.77 |
ENST00000547281.1
ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6 |
CDK4
|
cyclin-dependent kinase 4 |
| chr11_-_64014379 | 213.77 |
ENST00000309318.3
|
PPP1R14B
|
protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| chr2_-_10588630 | 198.46 |
ENST00000234111.4
|
ODC1
|
ornithine decarboxylase 1 |
| chr19_+_50180409 | 184.63 |
ENST00000391851.4
|
PRMT1
|
protein arginine methyltransferase 1 |
| chr19_+_50180507 | 181.90 |
ENST00000454376.2
ENST00000524771.1 |
PRMT1
|
protein arginine methyltransferase 1 |
| chr2_+_216176540 | 164.98 |
ENST00000236959.9
|
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| chr17_+_49230897 | 164.65 |
ENST00000393196.3
ENST00000336097.3 ENST00000480143.1 ENST00000511355.1 ENST00000013034.3 ENST00000393198.3 ENST00000608447.1 ENST00000393193.2 ENST00000376392.6 ENST00000555572.1 |
NME1
NME1-NME2
NME2
|
NME/NM23 nucleoside diphosphate kinase 1 NME1-NME2 readthrough NME/NM23 nucleoside diphosphate kinase 2 |
| chr4_+_57302297 | 162.90 |
ENST00000399688.3
ENST00000512576.1 |
PAICS
|
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| chrX_+_23685653 | 161.40 |
ENST00000379331.3
|
PRDX4
|
peroxiredoxin 4 |
| chr4_+_57301896 | 155.70 |
ENST00000514888.1
ENST00000264221.2 ENST00000505164.1 |
PAICS
|
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| chr8_+_55047763 | 152.16 |
ENST00000260102.4
ENST00000519831.1 |
MRPL15
|
mitochondrial ribosomal protein L15 |
| chr14_+_20923350 | 148.53 |
ENST00000555414.1
ENST00000216714.3 ENST00000553681.1 ENST00000557344.1 ENST00000398030.4 ENST00000557181.1 ENST00000555839.1 ENST00000553368.1 ENST00000556054.1 ENST00000557054.1 ENST00000557592.1 ENST00000557150.1 |
APEX1
|
APEX nuclease (multifunctional DNA repair enzyme) 1 |
| chr2_+_216176761 | 147.07 |
ENST00000540518.1
ENST00000435675.1 |
ATIC
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| chr22_+_20105259 | 129.06 |
ENST00000416427.1
ENST00000421656.1 ENST00000423859.1 ENST00000418705.2 |
RANBP1
|
RAN binding protein 1 |
| chr6_-_43197189 | 129.01 |
ENST00000509253.1
ENST00000393987.2 ENST00000230431.6 |
DNPH1
|
2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| chr1_+_43148625 | 127.79 |
ENST00000436427.1
|
YBX1
|
Y box binding protein 1 |
| chr1_-_11120057 | 127.51 |
ENST00000376957.2
|
SRM
|
spermidine synthase |
| chr2_+_113403434 | 122.79 |
ENST00000272542.3
|
SLC20A1
|
solute carrier family 20 (phosphate transporter), member 1 |
| chr8_+_98656336 | 118.06 |
ENST00000336273.3
|
MTDH
|
metadherin |
| chrX_+_23685563 | 113.84 |
ENST00000379341.4
|
PRDX4
|
peroxiredoxin 4 |
| chr9_+_131452239 | 110.94 |
ENST00000372688.4
ENST00000372686.5 |
SET
|
SET nuclear oncogene |
| chr13_+_27998681 | 105.80 |
ENST00000381140.4
|
GTF3A
|
general transcription factor IIIA |
| chr3_+_52719936 | 103.82 |
ENST00000418458.1
ENST00000394799.2 |
GNL3
|
guanine nucleotide binding protein-like 3 (nucleolar) |
| chr19_+_50180317 | 103.33 |
ENST00000534465.1
|
PRMT1
|
protein arginine methyltransferase 1 |
| chr7_+_150759634 | 98.63 |
ENST00000392826.2
ENST00000461735.1 |
SLC4A2
|
solute carrier family 4 (anion exchanger), member 2 |
| chr1_-_26233423 | 95.59 |
ENST00000357865.2
|
STMN1
|
stathmin 1 |
| chr19_-_2427863 | 94.82 |
ENST00000215570.3
|
TIMM13
|
translocase of inner mitochondrial membrane 13 homolog (yeast) |
| chr1_+_165797024 | 94.60 |
ENST00000372212.4
|
UCK2
|
uridine-cytidine kinase 2 |
| chr12_+_57624085 | 94.56 |
ENST00000553474.1
|
SHMT2
|
serine hydroxymethyltransferase 2 (mitochondrial) |
| chr19_-_10530784 | 93.43 |
ENST00000593124.1
|
CDC37
|
cell division cycle 37 |
| chr1_-_26232951 | 93.41 |
ENST00000426559.2
ENST00000455785.2 |
STMN1
|
stathmin 1 |
| chr17_-_47492164 | 92.44 |
ENST00000512041.2
ENST00000446735.1 ENST00000504124.1 |
PHB
|
prohibitin |
| chr17_+_49337881 | 91.69 |
ENST00000225298.7
|
UTP18
|
UTP18 small subunit (SSU) processome component homolog (yeast) |
| chr12_-_49318715 | 90.49 |
ENST00000444214.2
|
FKBP11
|
FK506 binding protein 11, 19 kDa |
| chr11_-_64013663 | 89.81 |
ENST00000392210.2
|
PPP1R14B
|
protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| chr6_-_33385854 | 88.93 |
ENST00000488478.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr2_+_198365122 | 86.23 |
ENST00000604458.1
|
HSPE1-MOB4
|
HSPE1-MOB4 readthrough |
| chr2_+_198365095 | 86.14 |
ENST00000409468.1
|
HSPE1
|
heat shock 10kDa protein 1 |
| chr12_+_57624119 | 84.23 |
ENST00000555773.1
ENST00000554975.1 ENST00000449049.3 ENST00000393827.4 |
SHMT2
|
serine hydroxymethyltransferase 2 (mitochondrial) |
| chr6_-_17706618 | 84.20 |
ENST00000262077.2
ENST00000537253.1 |
NUP153
|
nucleoporin 153kDa |
| chr4_-_99850243 | 82.49 |
ENST00000280892.6
ENST00000511644.1 ENST00000504432.1 ENST00000505992.1 |
EIF4E
|
eukaryotic translation initiation factor 4E |
| chr19_-_42806723 | 82.42 |
ENST00000262890.3
|
PAFAH1B3
|
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| chr11_-_122931881 | 81.55 |
ENST00000526110.1
ENST00000227378.3 |
HSPA8
|
heat shock 70kDa protein 8 |
| chr10_+_81107271 | 80.76 |
ENST00000448165.1
|
PPIF
|
peptidylprolyl isomerase F |
| chr20_+_44441304 | 80.52 |
ENST00000352551.5
|
UBE2C
|
ubiquitin-conjugating enzyme E2C |
| chr2_-_10587897 | 80.22 |
ENST00000405333.1
ENST00000443218.1 |
ODC1
|
ornithine decarboxylase 1 |
| chr17_+_49243792 | 78.78 |
ENST00000393183.3
ENST00000393190.1 |
NME1-NME2
|
NME1-NME2 readthrough |
| chr17_+_49243639 | 77.64 |
ENST00000512737.1
ENST00000503064.1 |
NME1-NME2
|
NME1-NME2 readthrough |
| chr1_-_8938736 | 76.89 |
ENST00000234590.4
|
ENO1
|
enolase 1, (alpha) |
| chr12_+_57623869 | 76.86 |
ENST00000414700.3
ENST00000557703.1 |
SHMT2
|
serine hydroxymethyltransferase 2 (mitochondrial) |
| chr14_-_58893832 | 76.58 |
ENST00000556007.2
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast) |
| chr8_+_97274119 | 75.75 |
ENST00000455950.2
|
PTDSS1
|
phosphatidylserine synthase 1 |
| chr18_+_12947981 | 74.89 |
ENST00000262124.11
|
SEH1L
|
SEH1-like (S. cerevisiae) |
| chr1_-_8939265 | 74.88 |
ENST00000489867.1
|
ENO1
|
enolase 1, (alpha) |
| chr16_-_87903079 | 74.81 |
ENST00000261622.4
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| chr11_+_114310164 | 74.77 |
ENST00000544196.1
ENST00000539754.1 ENST00000539275.1 |
REXO2
|
RNA exonuclease 2 |
| chr20_+_44441215 | 74.70 |
ENST00000356455.4
ENST00000405520.1 |
UBE2C
|
ubiquitin-conjugating enzyme E2C |
| chr21_-_46237883 | 74.23 |
ENST00000397893.3
|
SUMO3
|
small ubiquitin-like modifier 3 |
| chr14_-_58894223 | 73.89 |
ENST00000555593.1
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast) |
| chr19_-_2427536 | 73.04 |
ENST00000591871.1
|
TIMM13
|
translocase of inner mitochondrial membrane 13 homolog (yeast) |
| chr11_+_114310237 | 72.86 |
ENST00000539119.1
|
REXO2
|
RNA exonuclease 2 |
| chr6_-_33385655 | 72.75 |
ENST00000440279.3
ENST00000607266.1 |
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr22_+_20105012 | 72.63 |
ENST00000331821.3
ENST00000411892.1 |
RANBP1
|
RAN binding protein 1 |
| chr1_-_155232221 | 72.50 |
ENST00000355379.3
|
SCAMP3
|
secretory carrier membrane protein 3 |
| chr6_-_32811771 | 72.26 |
ENST00000395339.3
ENST00000374882.3 |
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8 |
| chr11_+_114310102 | 72.07 |
ENST00000265881.5
|
REXO2
|
RNA exonuclease 2 |
| chr16_-_81129845 | 70.73 |
ENST00000569885.1
ENST00000566566.1 |
GCSH
|
glycine cleavage system protein H (aminomethyl carrier) |
| chr1_-_43638168 | 70.46 |
ENST00000431635.2
|
EBNA1BP2
|
EBNA1 binding protein 2 |
| chr1_+_19578033 | 70.32 |
ENST00000330263.4
|
MRTO4
|
mRNA turnover 4 homolog (S. cerevisiae) |
| chr10_-_71993176 | 69.69 |
ENST00000373232.3
|
PPA1
|
pyrophosphatase (inorganic) 1 |
| chr6_-_8102714 | 68.96 |
ENST00000502429.1
ENST00000429723.2 ENST00000507463.1 ENST00000379715.5 |
EEF1E1
|
eukaryotic translation elongation factor 1 epsilon 1 |
| chr1_+_165796753 | 68.41 |
ENST00000367879.4
|
UCK2
|
uridine-cytidine kinase 2 |
| chr12_+_131356582 | 67.77 |
ENST00000448750.3
ENST00000541630.1 ENST00000392369.2 ENST00000254675.3 ENST00000535090.1 ENST00000392367.3 |
RAN
|
RAN, member RAS oncogene family |
| chr8_+_98656693 | 67.65 |
ENST00000519934.1
|
MTDH
|
metadherin |
| chr12_+_57623477 | 67.64 |
ENST00000557487.1
ENST00000555634.1 ENST00000556689.1 |
SHMT2
|
serine hydroxymethyltransferase 2 (mitochondrial) |
| chr10_-_120840309 | 66.42 |
ENST00000369144.3
|
EIF3A
|
eukaryotic translation initiation factor 3, subunit A |
| chr6_-_8102279 | 66.00 |
ENST00000488226.2
|
EEF1E1
|
eukaryotic translation elongation factor 1 epsilon 1 |
| chr7_+_100464760 | 65.27 |
ENST00000200457.4
|
TRIP6
|
thyroid hormone receptor interactor 6 |
| chr13_+_114238997 | 65.11 |
ENST00000538138.1
ENST00000375370.5 |
TFDP1
|
transcription factor Dp-1 |
| chr8_+_22224760 | 65.00 |
ENST00000359741.5
ENST00000520644.1 ENST00000240095.6 |
SLC39A14
|
solute carrier family 39 (zinc transporter), member 14 |
| chr2_+_27440229 | 64.76 |
ENST00000264705.4
ENST00000403525.1 |
CAD
|
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| chr1_-_155232047 | 63.77 |
ENST00000302631.3
|
SCAMP3
|
secretory carrier membrane protein 3 |
| chr1_+_111991474 | 62.74 |
ENST00000369722.3
|
ATP5F1
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 |
| chr6_-_33385823 | 62.49 |
ENST00000494751.1
ENST00000374496.3 |
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr12_+_64798095 | 61.56 |
ENST00000332707.5
|
XPOT
|
exportin, tRNA |
| chr17_+_76164639 | 61.43 |
ENST00000225777.3
ENST00000585591.1 ENST00000589711.1 ENST00000588282.1 ENST00000589168.1 |
SYNGR2
|
synaptogyrin 2 |
| chr17_+_42148225 | 61.40 |
ENST00000591696.1
|
G6PC3
|
glucose 6 phosphatase, catalytic, 3 |
| chr19_-_5719860 | 61.26 |
ENST00000590729.1
|
LONP1
|
lon peptidase 1, mitochondrial |
| chr12_+_66217911 | 60.65 |
ENST00000403681.2
|
HMGA2
|
high mobility group AT-hook 2 |
| chr17_+_36908984 | 60.40 |
ENST00000225426.4
ENST00000579088.1 |
PSMB3
|
proteasome (prosome, macropain) subunit, beta type, 3 |
| chr6_-_33385870 | 59.84 |
ENST00000488034.1
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr17_+_42148097 | 59.76 |
ENST00000269097.4
|
G6PC3
|
glucose 6 phosphatase, catalytic, 3 |
| chr11_+_844067 | 59.72 |
ENST00000397406.1
ENST00000409543.2 ENST00000525201.1 |
TSPAN4
|
tetraspanin 4 |
| chr19_-_5720123 | 59.18 |
ENST00000587365.1
ENST00000585374.1 ENST00000593119.1 |
LONP1
|
lon peptidase 1, mitochondrial |
| chr2_+_131100710 | 58.65 |
ENST00000452955.1
|
IMP4
|
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) |
| chr19_-_42806842 | 58.36 |
ENST00000596265.1
|
PAFAH1B3
|
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| chr9_+_112542591 | 58.10 |
ENST00000483909.1
ENST00000314527.4 ENST00000413420.1 ENST00000302798.7 ENST00000555236.1 ENST00000510514.5 |
PALM2
PALM2-AKAP2
AKAP2
|
paralemmin 2 PALM2-AKAP2 readthrough A kinase (PRKA) anchor protein 2 |
| chr9_-_113018835 | 57.93 |
ENST00000374517.5
|
TXN
|
thioredoxin |
| chr1_-_43637915 | 57.85 |
ENST00000236051.2
|
EBNA1BP2
|
EBNA1 binding protein 2 |
| chr17_+_65713925 | 57.13 |
ENST00000253247.4
|
NOL11
|
nucleolar protein 11 |
| chr12_+_108079664 | 57.12 |
ENST00000541166.1
|
PWP1
|
PWP1 homolog (S. cerevisiae) |
| chr1_-_159894319 | 56.91 |
ENST00000320307.4
|
TAGLN2
|
transgelin 2 |
| chr13_-_31038370 | 56.77 |
ENST00000399489.1
ENST00000339872.4 |
HMGB1
|
high mobility group box 1 |
| chr6_+_24775153 | 56.57 |
ENST00000356509.3
ENST00000230056.3 |
GMNN
|
geminin, DNA replication inhibitor |
| chr1_+_111992064 | 56.21 |
ENST00000483994.1
|
ATP5F1
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 |
| chr7_-_132766800 | 55.99 |
ENST00000542753.1
ENST00000448878.1 |
CHCHD3
|
coiled-coil-helix-coiled-coil-helix domain containing 3 |
| chr19_+_47634039 | 55.75 |
ENST00000597808.1
ENST00000413379.3 ENST00000600706.1 ENST00000540850.1 ENST00000598840.1 ENST00000600753.1 ENST00000270225.7 ENST00000392776.3 |
SAE1
|
SUMO1 activating enzyme subunit 1 |
| chr7_-_132766818 | 55.73 |
ENST00000262570.5
|
CHCHD3
|
coiled-coil-helix-coiled-coil-helix domain containing 3 |
| chr14_-_105487381 | 55.55 |
ENST00000392590.3
ENST00000336219.3 |
CDCA4
|
cell division cycle associated 4 |
| chr16_-_81129951 | 55.17 |
ENST00000315467.3
|
GCSH
|
glycine cleavage system protein H (aminomethyl carrier) |
| chr16_-_30441293 | 55.05 |
ENST00000565758.1
ENST00000567983.1 ENST00000319285.4 |
DCTPP1
|
dCTP pyrophosphatase 1 |
| chr2_+_131100423 | 55.02 |
ENST00000409935.1
ENST00000409649.1 ENST00000428740.1 |
IMP4
|
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) |
| chr9_+_91926103 | 54.84 |
ENST00000314355.6
|
CKS2
|
CDC28 protein kinase regulatory subunit 2 |
| chr12_+_104359576 | 54.23 |
ENST00000392872.3
ENST00000436021.2 |
TDG
|
thymine-DNA glycosylase |
| chr1_+_38478378 | 54.12 |
ENST00000373014.4
|
UTP11L
|
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) |
| chr3_-_183967296 | 54.05 |
ENST00000455059.1
ENST00000445626.2 |
ALG3
|
ALG3, alpha-1,3- mannosyltransferase |
| chrX_-_47518498 | 53.96 |
ENST00000335890.2
|
UXT
|
ubiquitously-expressed, prefoldin-like chaperone |
| chr13_+_76123883 | 53.95 |
ENST00000377595.3
|
UCHL3
|
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| chr8_-_102217796 | 53.89 |
ENST00000519744.1
ENST00000311212.4 ENST00000521272.1 ENST00000519882.1 |
ZNF706
|
zinc finger protein 706 |
| chr17_+_76165213 | 53.67 |
ENST00000590201.1
|
SYNGR2
|
synaptogyrin 2 |
| chr19_+_34855874 | 53.42 |
ENST00000588991.2
|
GPI
|
glucose-6-phosphate isomerase |
| chr6_+_32811885 | 53.29 |
ENST00000458296.1
ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1 |
TAPSAR1
PSMB9
|
TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9 |
| chr19_+_41768401 | 52.78 |
ENST00000352456.3
ENST00000595018.1 ENST00000597725.1 |
HNRNPUL1
|
heterogeneous nuclear ribonucleoprotein U-like 1 |
| chr20_+_31407692 | 52.48 |
ENST00000375571.5
|
MAPRE1
|
microtubule-associated protein, RP/EB family, member 1 |
| chr11_+_60609537 | 51.67 |
ENST00000227520.5
|
CCDC86
|
coiled-coil domain containing 86 |
| chr1_-_115259337 | 51.65 |
ENST00000369535.4
|
NRAS
|
neuroblastoma RAS viral (v-ras) oncogene homolog |
| chr19_-_40336969 | 51.24 |
ENST00000599134.1
ENST00000597634.1 ENST00000598417.1 ENST00000601274.1 ENST00000594309.1 ENST00000221801.3 |
FBL
|
fibrillarin |
| chr8_-_97273807 | 51.07 |
ENST00000517720.1
ENST00000287025.3 ENST00000523821.1 |
MTERFD1
|
MTERF domain containing 1 |
| chr17_+_7476136 | 50.82 |
ENST00000582169.1
ENST00000578754.1 ENST00000578495.1 ENST00000293831.8 ENST00000380512.5 ENST00000585024.1 ENST00000583802.1 ENST00000577269.1 ENST00000584784.1 ENST00000582746.1 |
EIF4A1
|
eukaryotic translation initiation factor 4A1 |
| chr11_+_34127142 | 50.79 |
ENST00000257829.3
ENST00000531159.2 |
NAT10
|
N-acetyltransferase 10 (GCN5-related) |
| chr8_-_117768023 | 50.71 |
ENST00000518949.1
ENST00000522453.1 ENST00000521861.1 ENST00000518995.1 |
EIF3H
|
eukaryotic translation initiation factor 3, subunit H |
| chrX_+_48433326 | 50.70 |
ENST00000376755.1
|
RBM3
|
RNA binding motif (RNP1, RRM) protein 3 |
| chr17_-_40075219 | 50.48 |
ENST00000537919.1
ENST00000352035.2 ENST00000353196.1 ENST00000393896.2 |
ACLY
|
ATP citrate lyase |
| chr11_-_118972575 | 50.39 |
ENST00000432443.2
|
DPAGT1
|
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
| chr3_+_127317066 | 50.35 |
ENST00000265056.7
|
MCM2
|
minichromosome maintenance complex component 2 |
| chr2_+_88991162 | 50.23 |
ENST00000283646.4
|
RPIA
|
ribose 5-phosphate isomerase A |
| chr17_-_47492236 | 50.17 |
ENST00000434917.2
ENST00000300408.3 ENST00000511832.1 ENST00000419140.2 |
PHB
|
prohibitin |
| chr11_+_9406169 | 50.12 |
ENST00000379719.3
ENST00000527431.1 |
IPO7
|
importin 7 |
| chr16_-_88851618 | 50.03 |
ENST00000301015.9
|
PIEZO1
|
piezo-type mechanosensitive ion channel component 1 |
| chr19_-_41903161 | 49.81 |
ENST00000602129.1
ENST00000593771.1 ENST00000596905.1 ENST00000221233.4 |
EXOSC5
|
exosome component 5 |
| chr17_-_48474828 | 49.13 |
ENST00000576448.1
ENST00000225972.7 |
LRRC59
|
leucine rich repeat containing 59 |
| chrX_-_47518527 | 49.11 |
ENST00000333119.3
|
UXT
|
ubiquitously-expressed, prefoldin-like chaperone |
| chr8_+_98788003 | 48.84 |
ENST00000521545.2
|
LAPTM4B
|
lysosomal protein transmembrane 4 beta |
| chr9_-_113018746 | 48.71 |
ENST00000374515.5
|
TXN
|
thioredoxin |
| chr7_-_23510086 | 48.50 |
ENST00000258729.3
|
IGF2BP3
|
insulin-like growth factor 2 mRNA binding protein 3 |
| chrX_-_16887963 | 48.18 |
ENST00000380084.4
|
RBBP7
|
retinoblastoma binding protein 7 |
| chr11_+_844406 | 47.95 |
ENST00000397404.1
|
TSPAN4
|
tetraspanin 4 |
| chr20_+_35202909 | 47.89 |
ENST00000558530.1
ENST00000558028.1 ENST00000560025.1 |
TGIF2-C20orf24
TGIF2
|
TGIF2-C20orf24 readthrough TGFB-induced factor homeobox 2 |
| chr12_+_96252706 | 47.63 |
ENST00000266735.5
ENST00000553192.1 ENST00000552085.1 |
SNRPF
|
small nuclear ribonucleoprotein polypeptide F |
| chr10_+_70715884 | 47.38 |
ENST00000354185.4
|
DDX21
|
DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| chr10_-_97416400 | 47.38 |
ENST00000371224.2
ENST00000371221.3 |
ALDH18A1
|
aldehyde dehydrogenase 18 family, member A1 |
| chr1_+_32479430 | 47.15 |
ENST00000327300.7
ENST00000492989.1 |
KHDRBS1
|
KH domain containing, RNA binding, signal transduction associated 1 |
| chr6_-_53213780 | 47.01 |
ENST00000304434.6
ENST00000370918.4 |
ELOVL5
|
ELOVL fatty acid elongase 5 |
| chr6_+_30689401 | 46.87 |
ENST00000396389.1
ENST00000396384.1 |
TUBB
|
tubulin, beta class I |
| chr6_-_33385902 | 46.82 |
ENST00000374500.5
|
CUTA
|
cutA divalent cation tolerance homolog (E. coli) |
| chr16_-_88878305 | 46.67 |
ENST00000569616.1
ENST00000563655.1 ENST00000567713.1 ENST00000426324.2 ENST00000378364.3 |
APRT
|
adenine phosphoribosyltransferase |
| chr5_+_172386419 | 46.61 |
ENST00000265100.2
ENST00000519239.1 |
RPL26L1
|
ribosomal protein L26-like 1 |
| chr21_-_46238034 | 46.27 |
ENST00000332859.6
|
SUMO3
|
small ubiquitin-like modifier 3 |
| chr11_+_18416133 | 46.20 |
ENST00000227157.4
ENST00000478970.2 ENST00000495052.1 |
LDHA
|
lactate dehydrogenase A |
| chr17_-_46688334 | 46.06 |
ENST00000239165.7
|
HOXB7
|
homeobox B7 |
| chr15_+_52311398 | 46.01 |
ENST00000261845.5
|
MAPK6
|
mitogen-activated protein kinase 6 |
| chr3_-_63849571 | 45.89 |
ENST00000295899.5
|
THOC7
|
THO complex 7 homolog (Drosophila) |
| chr4_-_2935674 | 45.85 |
ENST00000514800.1
|
MFSD10
|
major facilitator superfamily domain containing 10 |
| chr7_+_16685756 | 45.84 |
ENST00000415365.1
ENST00000258761.3 ENST00000433922.2 ENST00000452975.2 ENST00000405202.1 |
BZW2
|
basic leucine zipper and W2 domains 2 |
| chr6_+_44191290 | 45.67 |
ENST00000371755.3
ENST00000371740.5 ENST00000371731.1 ENST00000393841.1 |
SLC29A1
|
solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| chr1_-_40041925 | 45.34 |
ENST00000372862.3
|
PABPC4
|
poly(A) binding protein, cytoplasmic 4 (inducible form) |
| chr8_-_103668114 | 45.26 |
ENST00000285407.6
|
KLF10
|
Kruppel-like factor 10 |
| chr20_+_23331373 | 45.07 |
ENST00000254998.2
|
NXT1
|
NTF2-like export factor 1 |
| chr1_-_78148324 | 45.05 |
ENST00000370801.3
ENST00000433749.1 |
ZZZ3
|
zinc finger, ZZ-type containing 3 |
| chr19_+_5681153 | 44.78 |
ENST00000579559.1
ENST00000577222.1 |
HSD11B1L
RPL36
|
hydroxysteroid (11-beta) dehydrogenase 1-like ribosomal protein L36 |
| chr1_+_155178481 | 44.76 |
ENST00000368376.3
|
MTX1
|
metaxin 1 |
| chr17_+_40985407 | 44.74 |
ENST00000586114.1
ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1 |
PSME3
|
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
| chr5_-_133340326 | 44.61 |
ENST00000425992.1
ENST00000395044.3 ENST00000395047.2 |
VDAC1
|
voltage-dependent anion channel 1 |
| chr12_-_56709786 | 44.59 |
ENST00000547423.1
ENST00000548360.1 ENST00000551475.1 |
RP11-977G19.10
CNPY2
|
Uncharacterized protein canopy FGF signaling regulator 2 |
| chr3_-_131221790 | 44.21 |
ENST00000512877.1
ENST00000264995.3 ENST00000511168.1 ENST00000425847.2 |
MRPL3
|
mitochondrial ribosomal protein L3 |
| chr17_-_61850894 | 43.87 |
ENST00000403162.3
ENST00000582252.1 ENST00000225726.5 |
CCDC47
|
coiled-coil domain containing 47 |
| chr2_+_187350883 | 43.80 |
ENST00000337859.6
|
ZC3H15
|
zinc finger CCCH-type containing 15 |
| chr21_-_38445470 | 43.67 |
ENST00000399098.1
|
PIGP
|
phosphatidylinositol glycan anchor biosynthesis, class P |
| chr17_-_7590745 | 43.61 |
ENST00000514944.1
ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4 |
TP53
|
tumor protein p53 |
| chr6_-_153304148 | 43.61 |
ENST00000229758.3
|
FBXO5
|
F-box protein 5 |
| chr6_+_30689350 | 43.54 |
ENST00000330914.3
|
TUBB
|
tubulin, beta class I |
| chr1_-_86174065 | 43.54 |
ENST00000370574.3
ENST00000431532.2 |
ZNHIT6
|
zinc finger, HIT-type containing 6 |
| chr6_+_44191507 | 43.47 |
ENST00000371724.1
ENST00000371713.1 |
SLC29A1
|
solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| chr3_+_133293278 | 43.36 |
ENST00000508481.1
ENST00000420115.2 ENST00000504867.1 ENST00000507408.1 ENST00000511392.1 ENST00000515421.1 |
CDV3
|
CDV3 homolog (mouse) |
| chr6_-_7911042 | 43.27 |
ENST00000379757.4
|
TXNDC5
|
thioredoxin domain containing 5 (endoplasmic reticulum) |
| chr9_-_2844058 | 43.26 |
ENST00000397885.2
|
KIAA0020
|
KIAA0020 |
| chr10_-_16859361 | 43.19 |
ENST00000377921.3
|
RSU1
|
Ras suppressor protein 1 |
| chr10_+_75910960 | 43.15 |
ENST00000539909.1
ENST00000286621.2 |
ADK
|
adenosine kinase |
| chr2_-_175113088 | 42.96 |
ENST00000409546.1
ENST00000428402.2 |
OLA1
|
Obg-like ATPase 1 |
| chr14_-_54908043 | 42.93 |
ENST00000556113.1
ENST00000553660.1 ENST00000395573.4 ENST00000557690.1 ENST00000216416.4 |
CNIH1
|
cornichon family AMPA receptor auxiliary protein 1 |
| chr9_-_95087838 | 42.74 |
ENST00000442668.2
ENST00000421075.2 ENST00000536624.1 |
NOL8
|
nucleolar protein 8 |
| chr9_-_95087604 | 42.70 |
ENST00000542613.1
ENST00000542053.1 ENST00000358855.4 ENST00000545558.1 ENST00000432670.2 ENST00000433029.2 ENST00000411621.2 |
NOL8
|
nucleolar protein 8 |
| chrX_-_153285251 | 42.63 |
ENST00000444230.1
ENST00000393682.1 ENST00000393687.2 ENST00000429936.2 ENST00000369974.2 |
IRAK1
|
interleukin-1 receptor-associated kinase 1 |
| chr3_-_49066811 | 42.62 |
ENST00000442157.1
ENST00000326739.4 |
IMPDH2
|
IMP (inosine 5'-monophosphate) dehydrogenase 2 |
| chr12_+_109535923 | 42.40 |
ENST00000336865.2
|
UNG
|
uracil-DNA glycosylase |
| chr1_-_6259613 | 42.25 |
ENST00000465387.1
|
RPL22
|
ribosomal protein L22 |
| chr20_-_49547910 | 42.22 |
ENST00000396032.3
|
ADNP
|
activity-dependent neuroprotector homeobox |
| chr11_-_47664072 | 42.12 |
ENST00000542981.1
ENST00000530428.1 ENST00000302503.3 |
MTCH2
|
mitochondrial carrier 2 |
| chr11_-_57298187 | 42.10 |
ENST00000525158.1
ENST00000257245.4 ENST00000525587.1 |
TIMM10
|
translocase of inner mitochondrial membrane 10 homolog (yeast) |
Network of associatons between targets according to the STRING database.
First level regulatory network of MXI1_MYC_MYCN
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 95.6 | 478.1 | GO:1904636 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 78.0 | 312.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 76.6 | 459.4 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 69.7 | 278.7 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 58.9 | 294.5 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 52.4 | 367.0 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 51.1 | 153.3 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 50.5 | 252.3 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 49.5 | 148.5 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 49.3 | 394.7 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 43.5 | 391.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 40.8 | 163.0 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 37.6 | 112.7 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
| 37.6 | 112.7 | GO:0044209 | AMP salvage(GO:0044209) |
| 31.0 | 155.1 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
| 30.7 | 122.8 | GO:1902544 | oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544) |
| 30.3 | 90.9 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 27.5 | 55.0 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 26.9 | 80.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 26.4 | 26.4 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 25.4 | 76.3 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 25.4 | 50.8 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 25.4 | 126.8 | GO:0031126 | snoRNA 3'-end processing(GO:0031126) |
| 25.0 | 74.9 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 24.4 | 122.0 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 24.2 | 72.7 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 23.8 | 142.6 | GO:0045917 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 23.2 | 69.7 | GO:0071344 | diphosphate metabolic process(GO:0071344) |
| 23.0 | 184.0 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
| 22.3 | 66.8 | GO:0007057 | spindle assembly involved in female meiosis I(GO:0007057) |
| 22.1 | 66.4 | GO:0002188 | formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188) |
| 22.0 | 109.8 | GO:0015862 | uridine transport(GO:0015862) |
| 21.8 | 43.5 | GO:0048254 | snoRNA localization(GO:0048254) |
| 20.9 | 104.7 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 20.0 | 59.9 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 19.8 | 138.5 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 19.7 | 137.8 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 19.5 | 136.4 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 19.3 | 192.6 | GO:0018202 | peptidyl-histidine modification(GO:0018202) |
| 19.3 | 57.8 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 19.2 | 95.8 | GO:0007068 | negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070) |
| 18.7 | 187.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 18.6 | 74.3 | GO:0030920 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 18.4 | 147.0 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 17.3 | 121.2 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 17.3 | 69.1 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 17.0 | 34.0 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
| 16.4 | 49.3 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 16.2 | 48.7 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 15.8 | 47.3 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 15.7 | 125.9 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 15.5 | 62.1 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 15.3 | 30.5 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 15.2 | 45.6 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 15.1 | 60.5 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 15.0 | 74.8 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 14.9 | 59.7 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 14.6 | 73.1 | GO:0019640 | glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159) |
| 14.5 | 57.9 | GO:1902903 | regulation of fibril organization(GO:1902903) |
| 14.3 | 14.3 | GO:1904869 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
| 14.3 | 99.9 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 14.2 | 28.4 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 14.2 | 56.8 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 14.2 | 269.5 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 14.1 | 84.8 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 14.1 | 56.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 13.9 | 41.7 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 13.7 | 41.1 | GO:0035978 | mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685) |
| 13.6 | 40.8 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 13.6 | 40.8 | GO:0015883 | FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) |
| 13.4 | 120.7 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 13.4 | 80.2 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 13.3 | 26.6 | GO:0044416 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 13.1 | 26.3 | GO:0016074 | snoRNA metabolic process(GO:0016074) |
| 13.1 | 65.3 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 12.9 | 38.6 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 12.8 | 12.8 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
| 12.3 | 196.8 | GO:0002192 | IRES-dependent translational initiation(GO:0002192) |
| 12.3 | 36.8 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 12.3 | 122.8 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 12.3 | 36.8 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 12.2 | 48.8 | GO:0006218 | uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108) |
| 12.1 | 48.4 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 11.9 | 107.5 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 11.9 | 83.1 | GO:0002190 | cap-independent translational initiation(GO:0002190) |
| 11.8 | 47.2 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 11.7 | 70.4 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 11.7 | 23.5 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 11.6 | 69.6 | GO:0055129 | proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129) |
| 11.3 | 34.0 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 11.3 | 33.9 | GO:1901873 | regulation of post-translational protein modification(GO:1901873) |
| 11.0 | 21.9 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 10.9 | 21.9 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 10.8 | 140.7 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 10.7 | 107.1 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 10.6 | 265.5 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 10.5 | 41.9 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 10.3 | 31.0 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 10.2 | 30.6 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 10.2 | 61.0 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 10.2 | 60.9 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 9.9 | 39.8 | GO:0043335 | protein unfolding(GO:0043335) |
| 9.9 | 9.9 | GO:1901536 | regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
| 9.9 | 19.8 | GO:0019322 | pentose-phosphate shunt, oxidative branch(GO:0009051) pentose biosynthetic process(GO:0019322) |
| 9.9 | 406.0 | GO:0042407 | cristae formation(GO:0042407) |
| 9.9 | 39.5 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 9.9 | 148.1 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 9.9 | 49.3 | GO:0033490 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 9.8 | 19.7 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 9.8 | 49.1 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 9.7 | 19.4 | GO:0002906 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 9.7 | 48.3 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 9.6 | 57.8 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 9.5 | 28.6 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 9.5 | 9.5 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 9.5 | 75.8 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 9.5 | 66.2 | GO:0042113 | B cell activation(GO:0042113) |
| 9.4 | 18.8 | GO:0016321 | female meiosis chromosome segregation(GO:0016321) |
| 9.4 | 122.2 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
| 9.4 | 28.1 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 9.4 | 28.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 9.3 | 27.9 | GO:0048627 | myoblast development(GO:0048627) |
| 9.1 | 18.2 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 9.1 | 9.1 | GO:0072048 | pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) |
| 9.0 | 17.9 | GO:0044211 | CTP salvage(GO:0044211) |
| 8.9 | 26.6 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 8.9 | 142.0 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 8.8 | 35.4 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 8.7 | 26.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 8.6 | 86.0 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 8.5 | 59.7 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 8.4 | 41.9 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 8.4 | 41.8 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 8.4 | 58.5 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 8.2 | 98.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 8.1 | 81.3 | GO:0045008 | depyrimidination(GO:0045008) |
| 8.1 | 558.6 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 8.1 | 8.1 | GO:0090069 | regulation of ribosome biogenesis(GO:0090069) |
| 8.0 | 23.9 | GO:0000960 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 7.9 | 71.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 7.9 | 55.4 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 7.8 | 47.0 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 7.7 | 30.7 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 7.6 | 45.4 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 7.5 | 59.7 | GO:0045019 | negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406) |
| 7.5 | 29.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 7.5 | 149.1 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 7.4 | 22.2 | GO:1902499 | positive regulation of protein autoubiquitination(GO:1902499) |
| 7.3 | 51.4 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 7.3 | 87.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 7.2 | 29.0 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 7.2 | 519.9 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 7.2 | 28.7 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 7.1 | 21.4 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 7.1 | 42.5 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 6.9 | 20.8 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 6.9 | 20.8 | GO:0006738 | nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) |
| 6.9 | 20.7 | GO:0010628 | positive regulation of gene expression(GO:0010628) |
| 6.7 | 67.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 6.7 | 100.2 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 6.7 | 20.0 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 6.6 | 111.7 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 6.6 | 32.8 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 6.5 | 19.6 | GO:1902822 | lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822) |
| 6.5 | 45.7 | GO:0015755 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 6.5 | 13.0 | GO:1990542 | mitochondrial transmembrane transport(GO:1990542) |
| 6.5 | 32.3 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 6.5 | 45.2 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 6.4 | 38.7 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 6.4 | 25.7 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 6.4 | 12.8 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 6.4 | 44.9 | GO:0045002 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002) |
| 6.4 | 280.9 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 6.4 | 25.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 6.2 | 18.6 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 6.1 | 30.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 6.1 | 18.4 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 6.1 | 90.8 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 6.1 | 78.7 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 6.0 | 259.4 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 6.0 | 18.0 | GO:0040012 | regulation of locomotion(GO:0040012) |
| 6.0 | 42.0 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 6.0 | 12.0 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 6.0 | 17.9 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 5.9 | 17.8 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 5.9 | 29.6 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) |
| 5.8 | 17.5 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 5.8 | 115.8 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 5.8 | 17.4 | GO:0032759 | TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) |
| 5.7 | 17.1 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 5.7 | 17.1 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 5.7 | 11.4 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 5.7 | 537.3 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 5.6 | 89.9 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 5.6 | 16.8 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
| 5.5 | 16.5 | GO:0014736 | negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876) |
| 5.5 | 21.8 | GO:0001188 | RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189) |
| 5.4 | 21.8 | GO:1903438 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 5.4 | 21.8 | GO:0021564 | vagus nerve development(GO:0021564) |
| 5.4 | 10.7 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 5.3 | 10.6 | GO:1900369 | regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) |
| 5.2 | 187.7 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 5.2 | 20.8 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 5.2 | 15.6 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 5.2 | 20.6 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 5.2 | 20.6 | GO:0009956 | radial pattern formation(GO:0009956) |
| 5.1 | 162.8 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 5.1 | 15.2 | GO:0040013 | negative regulation of locomotion(GO:0040013) |
| 5.0 | 164.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 4.9 | 84.1 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 4.9 | 14.6 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 4.9 | 14.6 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 4.8 | 9.7 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 4.8 | 19.2 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 4.8 | 28.7 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 4.8 | 19.1 | GO:0000915 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 4.8 | 14.3 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 4.8 | 42.8 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 4.7 | 61.5 | GO:0030422 | production of siRNA involved in RNA interference(GO:0030422) |
| 4.7 | 23.3 | GO:0072553 | terminal button organization(GO:0072553) |
| 4.7 | 18.6 | GO:1903803 | glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803) |
| 4.6 | 18.6 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 4.6 | 18.6 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 4.6 | 45.9 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 4.6 | 13.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 4.5 | 13.4 | GO:0050917 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 4.5 | 13.4 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 4.4 | 93.4 | GO:0098779 | mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 4.4 | 26.6 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 4.4 | 26.5 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 4.4 | 13.1 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 4.4 | 13.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 4.3 | 30.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 4.3 | 64.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 4.3 | 12.8 | GO:0085032 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 4.3 | 21.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 4.2 | 12.7 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 4.2 | 314.5 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 4.2 | 25.4 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
| 4.2 | 33.7 | GO:0070141 | response to UV-A(GO:0070141) |
| 4.2 | 29.2 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 4.2 | 12.5 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 4.2 | 49.8 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 4.1 | 41.4 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 4.1 | 12.4 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 4.1 | 37.2 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 4.1 | 20.5 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 4.1 | 16.4 | GO:0002545 | chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) |
| 4.1 | 32.7 | GO:0006228 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 4.1 | 36.5 | GO:0006983 | ER overload response(GO:0006983) |
| 4.0 | 724.4 | GO:0006364 | rRNA processing(GO:0006364) |
| 4.0 | 20.1 | GO:2000377 | regulation of reactive oxygen species metabolic process(GO:2000377) |
| 4.0 | 12.0 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 3.9 | 11.8 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 3.9 | 23.5 | GO:0044413 | evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
| 3.9 | 15.6 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 3.9 | 34.7 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
| 3.8 | 19.1 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 3.8 | 41.5 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 3.7 | 11.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 3.7 | 15.0 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 3.7 | 11.2 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 3.7 | 3.7 | GO:0014806 | smooth muscle hyperplasia(GO:0014806) |
| 3.7 | 11.1 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 3.7 | 11.1 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 3.7 | 14.7 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) |
| 3.7 | 88.0 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 3.6 | 14.5 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
| 3.6 | 25.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 3.6 | 243.1 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 3.6 | 46.3 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 3.5 | 7.0 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 3.5 | 93.7 | GO:0034080 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 3.4 | 75.4 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 3.4 | 136.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 3.4 | 10.2 | GO:1901355 | response to rapamycin(GO:1901355) |
| 3.4 | 13.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 3.4 | 13.5 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 3.4 | 10.1 | GO:0042822 | pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
| 3.3 | 43.0 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 3.3 | 13.2 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 3.3 | 79.0 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 3.3 | 19.7 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 3.3 | 6.5 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 3.2 | 13.0 | GO:0051013 | microtubule severing(GO:0051013) |
| 3.2 | 34.7 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 3.1 | 18.9 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 3.1 | 6.2 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 3.1 | 6.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 3.1 | 12.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 3.0 | 3.0 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 3.0 | 9.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 3.0 | 12.0 | GO:0048478 | replication fork protection(GO:0048478) |
| 3.0 | 3.0 | GO:1903421 | regulation of synaptic vesicle recycling(GO:1903421) |
| 3.0 | 3.0 | GO:0072054 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 3.0 | 29.5 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 2.9 | 32.3 | GO:0006265 | DNA topological change(GO:0006265) |
| 2.9 | 11.7 | GO:1900125 | regulation of hyaluronan biosynthetic process(GO:1900125) |
| 2.9 | 20.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 2.9 | 17.5 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 2.9 | 5.8 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 2.9 | 8.6 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 2.9 | 37.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 2.9 | 2.9 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 2.9 | 25.8 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 2.8 | 5.7 | GO:0098502 | DNA dephosphorylation(GO:0098502) |
| 2.8 | 8.4 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 2.8 | 11.2 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 2.8 | 11.2 | GO:0015911 | plasma membrane long-chain fatty acid transport(GO:0015911) |
| 2.8 | 8.4 | GO:0032771 | regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910) |
| 2.8 | 8.3 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 2.7 | 32.6 | GO:0010663 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 2.6 | 23.7 | GO:0015074 | DNA integration(GO:0015074) |
| 2.6 | 28.7 | GO:0009414 | response to water deprivation(GO:0009414) |
| 2.6 | 51.5 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 2.6 | 10.3 | GO:0072683 | T cell extravasation(GO:0072683) |
| 2.6 | 10.2 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 2.6 | 2.6 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
| 2.6 | 150.7 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 2.5 | 188.3 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 2.5 | 38.1 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 2.5 | 22.8 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 2.5 | 10.1 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 2.5 | 32.6 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 2.5 | 7.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 2.5 | 47.5 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 2.5 | 12.5 | GO:0042695 | thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744) |
| 2.5 | 10.0 | GO:0035879 | plasma membrane lactate transport(GO:0035879) |
| 2.5 | 14.8 | GO:0048262 | determination of dorsal/ventral asymmetry(GO:0048262) |
| 2.4 | 26.9 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 2.4 | 9.7 | GO:0006551 | leucine metabolic process(GO:0006551) |
| 2.4 | 7.2 | GO:1901420 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420) |
| 2.4 | 7.2 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 2.4 | 31.0 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 2.4 | 16.6 | GO:1900223 | positive regulation of beta-amyloid clearance(GO:1900223) |
| 2.4 | 82.9 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 2.4 | 28.4 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 2.4 | 58.9 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 2.4 | 21.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 2.3 | 7.0 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 2.3 | 91.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 2.3 | 4.7 | GO:0071462 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) cellular response to water stimulus(GO:0071462) |
| 2.3 | 7.0 | GO:0061010 | gall bladder development(GO:0061010) |
| 2.3 | 14.0 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 2.3 | 18.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 2.3 | 9.3 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 2.3 | 4.6 | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731) |
| 2.3 | 13.8 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 2.3 | 16.0 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 2.3 | 18.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 2.3 | 78.9 | GO:1901998 | toxin transport(GO:1901998) |
| 2.2 | 71.7 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 2.2 | 9.0 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
| 2.2 | 6.7 | GO:0042727 | flavin-containing compound biosynthetic process(GO:0042727) |
| 2.2 | 10.9 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 2.1 | 21.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 2.1 | 4.3 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 2.1 | 17.2 | GO:1904753 | positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) |
| 2.1 | 21.5 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 2.1 | 14.8 | GO:0070836 | caveola assembly(GO:0070836) |
| 2.1 | 12.6 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
| 2.1 | 20.8 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 2.1 | 16.6 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 2.1 | 6.2 | GO:0036512 | trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512) |
| 2.1 | 4.1 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
| 2.1 | 33.0 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 2.0 | 16.4 | GO:1900625 | monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 2.0 | 8.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 2.0 | 4.0 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
| 2.0 | 3.9 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) |
| 2.0 | 11.7 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 1.9 | 15.6 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 1.9 | 15.5 | GO:0044351 | macropinocytosis(GO:0044351) |
| 1.9 | 3.9 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 1.9 | 3.9 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 1.9 | 19.2 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 1.9 | 15.4 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 1.9 | 9.6 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 1.9 | 19.2 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 1.9 | 37.8 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 1.9 | 17.0 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 1.9 | 3.8 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 1.9 | 11.2 | GO:0048143 | astrocyte activation(GO:0048143) |
| 1.9 | 7.4 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 1.9 | 3.7 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 1.9 | 5.6 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 1.9 | 1.9 | GO:1902908 | regulation of melanosome transport(GO:1902908) |
| 1.9 | 18.5 | GO:0001895 | retina homeostasis(GO:0001895) |
| 1.8 | 5.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 1.8 | 9.2 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 1.8 | 23.9 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 1.8 | 12.9 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 1.8 | 5.5 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 1.8 | 38.5 | GO:0006378 | mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631) |
| 1.8 | 20.0 | GO:0051451 | myoblast migration(GO:0051451) |
| 1.8 | 16.3 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 1.8 | 9.0 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) |
| 1.8 | 8.9 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 1.8 | 10.6 | GO:0032328 | alanine transport(GO:0032328) |
| 1.8 | 3.5 | GO:0042761 | fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761) |
| 1.7 | 15.7 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 1.7 | 13.9 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 1.7 | 3.5 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 1.7 | 5.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 1.7 | 12.0 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 1.7 | 6.8 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 1.7 | 1.7 | GO:1990791 | dorsal root ganglion development(GO:1990791) |
| 1.7 | 5.0 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 1.7 | 8.3 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 1.6 | 4.9 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 1.6 | 23.0 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 1.6 | 22.9 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 1.6 | 9.6 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 1.6 | 17.6 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 1.6 | 12.8 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 1.6 | 46.0 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 1.6 | 3.2 | GO:1903233 | regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) |
| 1.6 | 3.2 | GO:0071888 | macrophage apoptotic process(GO:0071888) |
| 1.6 | 23.8 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 1.6 | 7.9 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 1.6 | 1.6 | GO:0040031 | snRNA modification(GO:0040031) |
| 1.6 | 18.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 1.5 | 9.3 | GO:0010659 | cardiac muscle cell apoptotic process(GO:0010659) |
| 1.5 | 4.6 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 1.5 | 4.6 | GO:2000489 | regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.5 | 44.2 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 1.5 | 18.2 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 1.5 | 12.1 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 1.5 | 12.1 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.5 | 13.5 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 1.5 | 4.4 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 1.5 | 4.4 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 1.5 | 38.2 | GO:0006491 | N-glycan processing(GO:0006491) |
| 1.5 | 42.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 1.5 | 4.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 1.4 | 4.3 | GO:0045897 | positive regulation of transcription during mitosis(GO:0045897) |
| 1.4 | 14.4 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 1.4 | 27.3 | GO:0030488 | tRNA methylation(GO:0030488) |
| 1.4 | 15.8 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 1.4 | 1.4 | GO:0051182 | coenzyme transport(GO:0051182) |
| 1.4 | 5.6 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 1.4 | 132.9 | GO:0001909 | leukocyte mediated cytotoxicity(GO:0001909) |
| 1.4 | 14.9 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 1.3 | 30.8 | GO:0031640 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 1.3 | 5.3 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 1.3 | 8.0 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 1.3 | 4.0 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 1.3 | 18.4 | GO:0033630 | positive regulation of cell adhesion mediated by integrin(GO:0033630) |
| 1.3 | 34.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 1.3 | 3.9 | GO:0035989 | tendon development(GO:0035989) |
| 1.3 | 3.8 | GO:0044332 | Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) |
| 1.3 | 3.8 | GO:0043095 | regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105) |
| 1.3 | 7.5 | GO:0032594 | protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596) |
| 1.2 | 20.0 | GO:0090383 | phagosome acidification(GO:0090383) |
| 1.2 | 8.5 | GO:0060872 | semicircular canal development(GO:0060872) |
| 1.2 | 13.2 | GO:0030575 | nuclear body organization(GO:0030575) |
| 1.2 | 8.4 | GO:0000012 | single strand break repair(GO:0000012) |
| 1.2 | 2.4 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 1.2 | 15.5 | GO:0018027 | peptidyl-lysine dimethylation(GO:0018027) |
| 1.2 | 24.6 | GO:0097341 | inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) |
| 1.2 | 3.5 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 1.2 | 8.1 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 1.2 | 20.8 | GO:0008228 | opsonization(GO:0008228) |
| 1.2 | 5.8 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 1.2 | 1.2 | GO:0007405 | neuroblast proliferation(GO:0007405) |
| 1.1 | 6.8 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.1 | 6.7 | GO:0030421 | defecation(GO:0030421) |
| 1.1 | 33.6 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
| 1.1 | 2.2 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 1.1 | 21.0 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 1.1 | 8.8 | GO:0002759 | regulation of antimicrobial humoral response(GO:0002759) |
| 1.1 | 5.4 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 1.1 | 18.3 | GO:0002021 | response to dietary excess(GO:0002021) |
| 1.1 | 48.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 1.1 | 94.8 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 1.1 | 10.6 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
| 1.1 | 12.7 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 1.1 | 16.9 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 1.1 | 55.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 1.0 | 7.3 | GO:0034501 | protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459) |
| 1.0 | 6.2 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 1.0 | 12.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 1.0 | 4.1 | GO:0098838 | methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838) |
| 1.0 | 63.8 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 1.0 | 1.0 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis(GO:0032469) |
| 1.0 | 5.0 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 1.0 | 6.0 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 1.0 | 4.0 | GO:0033619 | membrane protein ectodomain proteolysis(GO:0006509) membrane protein proteolysis(GO:0033619) |
| 1.0 | 58.3 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 1.0 | 7.9 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 1.0 | 7.9 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 1.0 | 10.8 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 1.0 | 7.8 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 1.0 | 6.8 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 1.0 | 17.4 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 1.0 | 2.9 | GO:2000641 | regulation of early endosome to late endosome transport(GO:2000641) |
| 1.0 | 2.9 | GO:0032815 | negative regulation of natural killer cell activation(GO:0032815) |
| 0.9 | 6.6 | GO:0030656 | regulation of vitamin metabolic process(GO:0030656) |
| 0.9 | 16.0 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.9 | 0.9 | GO:0032423 | regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425) |
| 0.9 | 3.7 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.9 | 3.7 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.9 | 3.7 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.9 | 73.9 | GO:0006901 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.9 | 27.7 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.9 | 1.8 | GO:2001178 | mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178) |
| 0.9 | 8.9 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.9 | 6.2 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.9 | 10.6 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.9 | 3.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.9 | 1.7 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.9 | 4.3 | GO:0031947 | negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) |
| 0.9 | 28.1 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.8 | 9.2 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.8 | 17.4 | GO:0051923 | sulfation(GO:0051923) |
| 0.8 | 5.0 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
| 0.8 | 0.8 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.8 | 4.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.8 | 8.1 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.8 | 52.4 | GO:0006695 | cholesterol biosynthetic process(GO:0006695) |
| 0.8 | 8.8 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.8 | 7.1 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.8 | 33.8 | GO:0071479 | cellular response to ionizing radiation(GO:0071479) |
| 0.8 | 2.3 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 0.8 | 3.8 | GO:0031054 | pre-miRNA processing(GO:0031054) |
| 0.8 | 19.7 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.8 | 3.0 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.8 | 4.5 | GO:0031935 | regulation of chromatin silencing(GO:0031935) |
| 0.7 | 1.5 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.7 | 1.5 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.7 | 2.9 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.7 | 66.3 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.7 | 13.0 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.7 | 2.2 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.7 | 6.5 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.7 | 2.8 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.7 | 4.3 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.7 | 9.2 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.7 | 19.1 | GO:0033198 | response to ATP(GO:0033198) |
| 0.7 | 3.5 | GO:1901490 | regulation of lymphangiogenesis(GO:1901490) |
| 0.7 | 1.4 | GO:0033341 | regulation of collagen binding(GO:0033341) |
| 0.7 | 2.1 | GO:0042418 | epinephrine biosynthetic process(GO:0042418) |
| 0.7 | 4.1 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.7 | 6.1 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.7 | 2.0 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.7 | 5.3 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.7 | 1.3 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.7 | 4.6 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.7 | 2.6 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.7 | 7.9 | GO:0006505 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.7 | 14.3 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.6 | 37.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.6 | 3.2 | GO:0055070 | copper ion homeostasis(GO:0055070) |
| 0.6 | 1.9 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.6 | 0.6 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.6 | 3.8 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.6 | 2.5 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.6 | 4.3 | GO:1990090 | response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.6 | 23.9 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.6 | 19.6 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.6 | 4.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.6 | 8.5 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
| 0.6 | 3.0 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.6 | 9.9 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
| 0.6 | 21.4 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.6 | 6.9 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.6 | 10.8 | GO:0008284 | positive regulation of cell proliferation(GO:0008284) |
| 0.6 | 6.2 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.6 | 3.4 | GO:0032488 | Cdc42 protein signal transduction(GO:0032488) |
| 0.6 | 1.7 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.5 | 2.2 | GO:0007249 | I-kappaB kinase/NF-kappaB signaling(GO:0007249) |
| 0.5 | 9.8 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.5 | 6.4 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.5 | 0.5 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.5 | 1.1 | GO:1901224 | positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 0.5 | 1.6 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.5 | 8.3 | GO:0032400 | melanosome localization(GO:0032400) |
| 0.5 | 2.1 | GO:0098780 | response to mitochondrial depolarisation(GO:0098780) |
| 0.5 | 1.0 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
| 0.5 | 9.5 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.5 | 3.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.5 | 7.4 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.5 | 6.9 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.5 | 5.9 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.5 | 3.4 | GO:0060561 | apoptotic process involved in morphogenesis(GO:0060561) |
| 0.5 | 4.4 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.5 | 9.7 | GO:0070585 | protein localization to mitochondrion(GO:0070585) |
| 0.5 | 10.1 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.5 | 22.6 | GO:0007569 | cell aging(GO:0007569) |
| 0.5 | 10.3 | GO:0006413 | translational initiation(GO:0006413) |
| 0.5 | 1.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.5 | 21.7 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.5 | 3.7 | GO:0030316 | osteoclast differentiation(GO:0030316) |
| 0.5 | 1.8 | GO:0060579 | ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
| 0.5 | 6.3 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.5 | 25.3 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.5 | 1.8 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.4 | 3.6 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.4 | 1.3 | GO:1901202 | negative regulation of extracellular matrix assembly(GO:1901202) |
| 0.4 | 8.4 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
| 0.4 | 4.4 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.4 | 2.6 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.4 | 6.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.4 | 22.6 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.4 | 2.5 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.4 | 4.4 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.4 | 5.3 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.4 | 3.4 | GO:0030099 | myeloid cell differentiation(GO:0030099) |
| 0.4 | 1.1 | GO:0043461 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.4 | 10.8 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.4 | 9.5 | GO:0008209 | androgen metabolic process(GO:0008209) |
| 0.3 | 3.1 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.3 | 7.1 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.3 | 2.7 | GO:0019934 | cGMP-mediated signaling(GO:0019934) |
| 0.3 | 0.3 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.3 | 3.0 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.3 | 0.7 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
| 0.3 | 1.6 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.3 | 1.6 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.3 | 2.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.3 | 3.2 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.3 | 4.1 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.3 | 1.3 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.3 | 0.6 | GO:0016246 | RNA interference(GO:0016246) |
| 0.3 | 1.2 | GO:0033690 | positive regulation of osteoblast proliferation(GO:0033690) |
| 0.3 | 4.0 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.3 | 45.4 | GO:0006457 | protein folding(GO:0006457) |
| 0.3 | 2.1 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.3 | 2.7 | GO:0015682 | ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512) |
| 0.3 | 1.5 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.3 | 5.0 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.3 | 3.2 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.3 | 1.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.3 | 12.8 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.3 | 3.1 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.3 | 4.5 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.3 | 10.0 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.3 | 1.7 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.3 | 8.6 | GO:0051341 | regulation of oxidoreductase activity(GO:0051341) |
| 0.3 | 5.9 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.3 | 1.1 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.3 | 0.8 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.3 | 3.8 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.3 | 7.1 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.2 | 5.2 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.2 | 3.6 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.2 | 1.7 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.2 | 6.0 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 0.7 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.2 | 0.9 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.2 | 6.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.2 | 1.4 | GO:0006636 | unsaturated fatty acid biosynthetic process(GO:0006636) |
| 0.2 | 2.0 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.2 | 1.8 | GO:0006751 | glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.2 | 6.5 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 0.2 | 5.6 | GO:2001022 | positive regulation of response to DNA damage stimulus(GO:2001022) |
| 0.2 | 5.5 | GO:0014823 | response to activity(GO:0014823) |
| 0.2 | 1.4 | GO:0000724 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.2 | 2.0 | GO:0036344 | platelet morphogenesis(GO:0036344) |
| 0.2 | 2.0 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.2 | 2.8 | GO:0045086 | positive regulation of interleukin-2 biosynthetic process(GO:0045086) |
| 0.2 | 2.2 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.2 | 0.8 | GO:0030728 | ovulation(GO:0030728) |
| 0.2 | 2.8 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 1.1 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.2 | 4.2 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.2 | 1.4 | GO:0006568 | tryptophan metabolic process(GO:0006568) |
| 0.2 | 0.4 | GO:0015709 | thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356) |
| 0.2 | 2.8 | GO:0017145 | stem cell division(GO:0017145) |
| 0.2 | 3.3 | GO:0033146 | regulation of intracellular estrogen receptor signaling pathway(GO:0033146) |
| 0.2 | 1.7 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.2 | 10.4 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.2 | 1.4 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.2 | 2.2 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.2 | 1.2 | GO:0055012 | ventricular cardiac muscle cell differentiation(GO:0055012) |
| 0.2 | 1.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.2 | 2.6 | GO:0042438 | melanin biosynthetic process(GO:0042438) |
| 0.2 | 3.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.2 | 3.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.2 | 2.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.2 | 1.1 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.2 | 4.1 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.2 | 1.5 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.1 | 5.5 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
| 0.1 | 2.7 | GO:0019915 | lipid storage(GO:0019915) |
| 0.1 | 2.1 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 1.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.4 | GO:0010193 | response to ozone(GO:0010193) |
| 0.1 | 1.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 0.7 | GO:0009650 | UV protection(GO:0009650) |
| 0.1 | 3.1 | GO:0032801 | receptor catabolic process(GO:0032801) |
| 0.1 | 1.5 | GO:0045471 | response to ethanol(GO:0045471) |
| 0.1 | 0.6 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.1 | 1.0 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.1 | 0.4 | GO:0032776 | DNA methylation on cytosine(GO:0032776) |
| 0.1 | 0.1 | GO:0002644 | negative regulation of tolerance induction(GO:0002644) |
| 0.1 | 24.4 | GO:0010038 | response to metal ion(GO:0010038) |
| 0.1 | 0.8 | GO:0048311 | mitochondrion distribution(GO:0048311) |
| 0.1 | 0.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.7 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.6 | GO:0072319 | vesicle uncoating(GO:0072319) |
| 0.1 | 0.4 | GO:0046831 | regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831) |
| 0.1 | 1.9 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 0.5 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.1 | 0.4 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 0.6 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.9 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.1 | 5.3 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.1 | 1.1 | GO:0045638 | negative regulation of myeloid cell differentiation(GO:0045638) |
| 0.1 | 0.8 | GO:0030210 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 0.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.2 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.1 | 10.1 | GO:0016042 | lipid catabolic process(GO:0016042) |
| 0.1 | 0.4 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.1 | 0.3 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.1 | 0.4 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.1 | 0.2 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) |
| 0.1 | 0.4 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.1 | 0.5 | GO:0097070 | ductus arteriosus closure(GO:0097070) |
| 0.1 | 0.1 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.1 | 0.1 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.3 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.5 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 1.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.5 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.1 | GO:0014063 | regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063) |
| 0.0 | 0.2 | GO:1901660 | calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034) |
| 0.0 | 0.4 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.1 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) regulation of interleukin-1 alpha secretion(GO:0050705) |
| 0.0 | 1.1 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 0.1 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.0 | 0.2 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 0.2 | GO:0006720 | isoprenoid metabolic process(GO:0006720) terpenoid metabolic process(GO:0006721) |
| 0.0 | 0.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
| 0.0 | 0.1 | GO:0014856 | skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) |
| 0.0 | 0.2 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.0 | 0.0 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 0.4 | GO:0050881 | multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 80.6 | 483.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 48.9 | 391.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 40.7 | 122.0 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 40.4 | 323.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 33.4 | 601.3 | GO:0034709 | methylosome(GO:0034709) |
| 30.2 | 181.4 | GO:0090661 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 28.3 | 84.8 | GO:0034455 | t-UTP complex(GO:0034455) |
| 26.7 | 133.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 26.6 | 186.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 26.5 | 132.6 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 25.3 | 151.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 24.0 | 167.9 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 23.6 | 118.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 23.1 | 69.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 20.8 | 166.8 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 19.7 | 137.8 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 19.6 | 78.3 | GO:0070985 | TFIIK complex(GO:0070985) |
| 19.3 | 173.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 18.7 | 130.9 | GO:0031415 | NatA complex(GO:0031415) |
| 17.9 | 125.4 | GO:0061617 | MICOS complex(GO:0061617) |
| 16.4 | 49.1 | GO:0097447 | dendritic tree(GO:0097447) |
| 16.1 | 64.6 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 14.8 | 103.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 14.5 | 72.7 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 13.9 | 55.7 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 13.8 | 248.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 13.5 | 81.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 12.5 | 124.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 11.8 | 47.3 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 11.8 | 11.8 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 11.7 | 93.4 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 11.3 | 11.3 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 11.1 | 77.6 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 10.8 | 32.5 | GO:0001740 | Barr body(GO:0001740) |
| 10.8 | 32.3 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 10.5 | 20.9 | GO:0030689 | Noc complex(GO:0030689) |
| 10.4 | 229.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 10.3 | 102.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 10.3 | 215.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 10.1 | 253.1 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 10.0 | 120.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 9.9 | 49.5 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 9.7 | 38.7 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 9.3 | 65.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 9.2 | 27.7 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
| 9.2 | 36.8 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 9.1 | 45.3 | GO:0002169 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 8.8 | 52.7 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 8.7 | 52.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 8.5 | 17.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 8.5 | 110.9 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 8.5 | 374.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 8.5 | 17.0 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 8.5 | 101.7 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 8.4 | 336.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 8.4 | 25.2 | GO:0044393 | microspike(GO:0044393) |
| 8.4 | 41.8 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 8.3 | 41.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 8.1 | 97.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 8.0 | 80.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 8.0 | 207.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 7.9 | 142.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 7.8 | 133.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 7.8 | 62.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 7.7 | 85.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 7.5 | 67.5 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 7.5 | 119.6 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 7.5 | 44.7 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 7.4 | 22.3 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 7.4 | 81.6 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 7.4 | 377.1 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 7.3 | 117.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 7.2 | 78.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 7.1 | 21.4 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 7.1 | 214.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 6.9 | 20.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 6.6 | 6.6 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 6.6 | 45.9 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 6.5 | 58.3 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 6.2 | 73.9 | GO:0090543 | Flemming body(GO:0090543) |
| 5.9 | 47.0 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 5.8 | 17.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 5.7 | 57.3 | GO:0030686 | 90S preribosome(GO:0030686) |
| 5.7 | 28.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 5.7 | 56.8 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 5.4 | 76.0 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 5.3 | 565.5 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 5.3 | 21.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 5.1 | 20.2 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 5.0 | 60.6 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 5.0 | 30.0 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 5.0 | 79.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 4.9 | 53.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 4.7 | 51.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 4.6 | 105.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 4.5 | 36.2 | GO:0097255 | R2TP complex(GO:0097255) |
| 4.5 | 44.7 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 4.4 | 13.3 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 4.4 | 21.9 | GO:0033503 | HULC complex(GO:0033503) |
| 4.4 | 39.2 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 4.4 | 13.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 4.3 | 108.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 4.3 | 65.0 | GO:0005686 | U2 snRNP(GO:0005686) |
| 4.3 | 47.2 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 4.3 | 114.9 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 4.2 | 38.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 4.2 | 42.2 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 4.1 | 16.6 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 4.1 | 24.6 | GO:0035861 | site of double-strand break(GO:0035861) |
| 4.0 | 16.0 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 4.0 | 12.0 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 3.9 | 3.9 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
| 3.8 | 26.6 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 3.7 | 11.1 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) tubular endosome(GO:0097422) |
| 3.6 | 286.8 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 3.6 | 14.2 | GO:0001940 | male pronucleus(GO:0001940) |
| 3.5 | 130.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 3.5 | 10.6 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 3.5 | 13.9 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 3.4 | 30.8 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 3.4 | 30.6 | GO:0097413 | Lewy body(GO:0097413) |
| 3.4 | 27.0 | GO:0031931 | TORC1 complex(GO:0031931) |
| 3.4 | 26.8 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 3.3 | 13.4 | GO:0098800 | inner mitochondrial membrane protein complex(GO:0098800) |
| 3.3 | 26.7 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 3.3 | 33.4 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 3.3 | 443.7 | GO:0016605 | PML body(GO:0016605) |
| 3.3 | 43.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 3.3 | 46.4 | GO:0005685 | U1 snRNP(GO:0005685) |
| 3.3 | 46.3 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 3.3 | 13.1 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 3.2 | 29.1 | GO:0044194 | cytolytic granule(GO:0044194) |
| 3.2 | 74.2 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 3.2 | 345.9 | GO:0005840 | ribosome(GO:0005840) |
| 3.1 | 74.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 3.1 | 161.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 3.0 | 24.3 | GO:0005814 | centriole(GO:0005814) |
| 3.0 | 9.0 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 3.0 | 15.0 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 3.0 | 529.4 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 2.9 | 191.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 2.8 | 31.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 2.8 | 53.5 | GO:0071437 | invadopodium(GO:0071437) |
| 2.8 | 8.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 2.8 | 16.6 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 2.7 | 10.7 | GO:0009368 | endopeptidase Clp complex(GO:0009368) |
| 2.7 | 96.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 2.7 | 39.9 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 2.6 | 13.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 2.6 | 13.0 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 2.5 | 5.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 2.5 | 12.4 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 2.5 | 9.8 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 2.4 | 48.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 2.4 | 14.6 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 2.4 | 23.7 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 2.3 | 18.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 2.3 | 11.4 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 2.2 | 22.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 2.2 | 11.2 | GO:0000938 | GARP complex(GO:0000938) |
| 2.2 | 4.4 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 2.2 | 11.0 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 2.2 | 8.7 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 2.1 | 23.2 | GO:0042555 | MCM complex(GO:0042555) |
| 2.1 | 6.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 2.0 | 38.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 2.0 | 4.0 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 2.0 | 17.6 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.9 | 7.8 | GO:0055087 | Ski complex(GO:0055087) |
| 1.9 | 16.9 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 1.9 | 1.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 1.8 | 5.5 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 1.8 | 27.2 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 1.8 | 18.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 1.8 | 3.6 | GO:0045259 | proton-transporting ATP synthase complex(GO:0045259) |
| 1.8 | 32.4 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 1.8 | 14.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 1.7 | 132.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 1.6 | 6.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 1.6 | 18.0 | GO:0043601 | nuclear replisome(GO:0043601) |
| 1.6 | 178.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 1.6 | 110.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 1.6 | 57.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 1.6 | 17.6 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 1.5 | 95.0 | GO:0005903 | brush border(GO:0005903) |
| 1.5 | 29.1 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 1.5 | 19.6 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 1.5 | 12.0 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 1.5 | 25.2 | GO:0032059 | bleb(GO:0032059) |
| 1.5 | 17.6 | GO:0030008 | TRAPP complex(GO:0030008) |
| 1.5 | 80.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 1.4 | 5.8 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 1.4 | 5.6 | GO:0098576 | lumenal side of membrane(GO:0098576) |
| 1.4 | 33.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 1.4 | 111.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 1.4 | 63.8 | GO:0043034 | costamere(GO:0043034) |
| 1.3 | 4.0 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 1.3 | 31.9 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 1.3 | 14.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 1.3 | 85.7 | GO:0005811 | lipid particle(GO:0005811) |
| 1.3 | 14.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 1.3 | 43.8 | GO:0031941 | filamentous actin(GO:0031941) |
| 1.2 | 16.0 | GO:0031209 | SCAR complex(GO:0031209) |
| 1.2 | 9.8 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
| 1.2 | 28.2 | GO:0097228 | sperm principal piece(GO:0097228) |
| 1.2 | 8.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 1.2 | 12.8 | GO:0030904 | retromer complex(GO:0030904) |
| 1.2 | 4.6 | GO:0035838 | growing cell tip(GO:0035838) |
| 1.2 | 12.7 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 1.1 | 59.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 1.1 | 5.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 1.1 | 5.7 | GO:0001739 | sex chromatin(GO:0001739) |
| 1.1 | 5.6 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.1 | 63.4 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 1.1 | 4.3 | GO:0016589 | NURF complex(GO:0016589) |
| 1.1 | 3242.0 | GO:0070062 | extracellular exosome(GO:0070062) |
| 1.1 | 31.2 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 1.1 | 9.6 | GO:0097470 | ribbon synapse(GO:0097470) |
| 1.0 | 11.3 | GO:0030673 | axolemma(GO:0030673) |
| 1.0 | 20.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 1.0 | 4.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 1.0 | 2.9 | GO:1902554 | serine/threonine protein kinase complex(GO:1902554) |
| 1.0 | 3.8 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.9 | 10.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.9 | 11.9 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.9 | 155.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.9 | 4.4 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.8 | 40.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.8 | 4.0 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.8 | 15.9 | GO:0005657 | replication fork(GO:0005657) |
| 0.7 | 2.2 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.7 | 5.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.7 | 2.1 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.7 | 2.7 | GO:0005846 | nuclear cap binding complex(GO:0005846) |
| 0.7 | 67.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.7 | 155.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.7 | 3.9 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.7 | 2.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.6 | 0.6 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.6 | 32.8 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.6 | 5.5 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.6 | 52.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.6 | 4.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.6 | 6.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.6 | 33.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.6 | 5.0 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.5 | 1.6 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.5 | 37.7 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.5 | 14.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.5 | 3.0 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.5 | 13.4 | GO:0042641 | actomyosin(GO:0042641) |
| 0.5 | 6.7 | GO:0030057 | desmosome(GO:0030057) |
| 0.4 | 1.8 | GO:0000306 | extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313) |
| 0.4 | 1.6 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.4 | 6.4 | GO:0002102 | podosome(GO:0002102) |
| 0.4 | 1.2 | GO:0031417 | NatC complex(GO:0031417) |
| 0.4 | 36.5 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.4 | 2.5 | GO:0032039 | integrator complex(GO:0032039) |
| 0.4 | 4.2 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.3 | 6.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.3 | 5.5 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.3 | 1.4 | GO:1990031 | pinceau fiber(GO:1990031) |
| 0.3 | 9.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.3 | 4.6 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.3 | 2.8 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.3 | 9.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.3 | 1.6 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 2.7 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.2 | 3.1 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 1.1 | GO:0032449 | CBM complex(GO:0032449) |
| 0.2 | 0.4 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.2 | 3.1 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 10.2 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 1.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.2 | 1.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 1.2 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.2 | 4.5 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.2 | 9.2 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.2 | 2.3 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 1.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.2 | 2.8 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.5 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.1 | 5.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 2.9 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.1 | 0.5 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 0.6 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 0.6 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 2.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 44.5 | GO:0005730 | nucleolus(GO:0005730) |
| 0.1 | 0.3 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.1 | 0.6 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 0.5 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.4 | GO:0031932 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 0.1 | 0.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.0 | 0.1 | GO:0031672 | A band(GO:0031672) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 81.2 | 487.2 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 56.3 | 337.7 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 52.4 | 367.0 | GO:0004793 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 51.1 | 153.3 | GO:0070364 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 49.5 | 148.5 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
| 46.8 | 374.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 45.1 | 135.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 42.5 | 127.5 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 40.9 | 122.8 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 40.2 | 201.0 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 37.6 | 112.7 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
| 36.5 | 146.0 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 31.5 | 125.9 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 30.7 | 122.8 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 30.3 | 121.2 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 30.2 | 181.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 28.7 | 86.2 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 25.9 | 181.0 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 25.3 | 151.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 25.0 | 74.9 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 24.9 | 99.6 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
| 23.1 | 69.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 23.0 | 69.0 | GO:0002134 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) |
| 21.6 | 64.8 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 21.3 | 106.6 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 20.2 | 80.9 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 19.8 | 79.4 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 19.4 | 19.4 | GO:0004167 | dopachrome isomerase activity(GO:0004167) |
| 19.3 | 57.9 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 19.3 | 57.8 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 19.1 | 57.3 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 18.6 | 74.3 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 18.2 | 218.4 | GO:0031386 | protein tag(GO:0031386) |
| 17.9 | 250.9 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 17.4 | 69.7 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 16.9 | 118.2 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 16.9 | 67.4 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 16.8 | 50.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 16.7 | 367.7 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 15.8 | 646.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 15.6 | 78.0 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 15.5 | 46.5 | GO:0098625 | methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626) |
| 15.2 | 60.9 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 14.4 | 101.0 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 13.7 | 41.1 | GO:0035501 | MH1 domain binding(GO:0035501) |
| 13.6 | 40.8 | GO:0015230 | FAD transmembrane transporter activity(GO:0015230) |
| 13.2 | 39.5 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 12.9 | 38.6 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 12.8 | 51.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 12.8 | 76.6 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 12.7 | 126.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 12.6 | 100.8 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 12.5 | 124.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 12.4 | 24.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 12.3 | 36.8 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 12.2 | 48.8 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 12.1 | 36.3 | GO:0004797 | thymidine kinase activity(GO:0004797) |
| 11.8 | 47.0 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 11.6 | 104.7 | GO:0055104 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 11.6 | 347.0 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 11.3 | 34.0 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 11.3 | 56.6 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 11.1 | 77.7 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 11.0 | 55.0 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
| 10.6 | 42.5 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 10.4 | 41.4 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 10.3 | 277.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 10.1 | 71.0 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 9.9 | 9.9 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 9.9 | 39.5 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 9.8 | 206.1 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 9.7 | 58.3 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 9.7 | 456.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 9.7 | 48.3 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 9.6 | 77.1 | GO:0016997 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) |
| 9.6 | 57.8 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 9.5 | 19.0 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 9.5 | 47.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 9.5 | 56.8 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 9.4 | 28.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 9.3 | 27.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 9.1 | 73.0 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 9.1 | 136.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 9.1 | 45.3 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 9.0 | 224.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 8.9 | 80.1 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 8.8 | 97.2 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 8.6 | 60.5 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 8.6 | 25.8 | GO:0030984 | kininogen binding(GO:0030984) |
| 8.5 | 76.5 | GO:0015288 | porin activity(GO:0015288) |
| 8.5 | 25.4 | GO:0004608 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 8.3 | 148.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 8.2 | 221.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 8.1 | 64.6 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 8.1 | 24.2 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 7.9 | 103.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 7.9 | 39.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 7.9 | 142.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 7.9 | 39.3 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 7.8 | 31.1 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 7.7 | 263.2 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 7.7 | 99.8 | GO:0030957 | Tat protein binding(GO:0030957) |
| 7.7 | 23.0 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 7.6 | 106.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 7.3 | 210.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 7.2 | 333.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 7.2 | 36.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 7.2 | 21.7 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 7.2 | 14.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 7.2 | 122.4 | GO:0004549 | tRNA-specific ribonuclease activity(GO:0004549) |
| 7.2 | 21.5 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 7.1 | 134.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 7.0 | 21.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 6.9 | 165.7 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 6.9 | 27.6 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
| 6.9 | 68.5 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 6.8 | 41.1 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 6.7 | 33.6 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 6.5 | 45.7 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 6.5 | 156.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 6.5 | 77.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 6.4 | 6.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 6.4 | 44.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 6.3 | 63.4 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 6.2 | 49.8 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 6.2 | 31.0 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 6.2 | 111.7 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 6.2 | 18.6 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 6.2 | 61.6 | GO:0042731 | PH domain binding(GO:0042731) |
| 6.1 | 349.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 6.1 | 61.3 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 6.1 | 18.2 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 6.1 | 42.4 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 5.8 | 447.3 | GO:0005507 | copper ion binding(GO:0005507) |
| 5.8 | 17.4 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 5.8 | 28.9 | GO:0052834 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 5.6 | 22.6 | GO:0008670 | 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) |
| 5.6 | 16.8 | GO:0070025 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
| 5.5 | 22.2 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 5.5 | 16.6 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
| 5.5 | 1107.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 5.4 | 5.4 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 5.4 | 32.3 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 5.3 | 216.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 5.2 | 10.4 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 5.2 | 15.5 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 5.1 | 72.0 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 5.1 | 20.5 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 5.0 | 15.0 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 5.0 | 15.0 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 5.0 | 34.7 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 4.9 | 14.8 | GO:0004170 | dUTP diphosphatase activity(GO:0004170) |
| 4.9 | 14.8 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 4.8 | 178.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 4.8 | 53.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 4.8 | 81.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 4.7 | 32.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 4.6 | 18.6 | GO:0004619 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 4.6 | 41.3 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 4.5 | 22.5 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 4.5 | 53.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 4.5 | 26.9 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 4.5 | 13.4 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 4.4 | 13.2 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 4.4 | 13.1 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 4.3 | 100.0 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 4.3 | 13.0 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 4.3 | 218.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 4.3 | 128.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 4.3 | 47.0 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 4.3 | 17.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 4.3 | 21.3 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 4.2 | 104.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 4.2 | 16.7 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 4.1 | 12.3 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 4.0 | 12.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 4.0 | 60.5 | GO:0070061 | fructose binding(GO:0070061) |
| 4.0 | 56.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 4.0 | 12.0 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 4.0 | 16.0 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 4.0 | 79.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 3.9 | 23.5 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 3.9 | 11.7 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 3.9 | 15.5 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 3.8 | 26.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 3.8 | 26.8 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 3.8 | 328.3 | GO:0051087 | chaperone binding(GO:0051087) |
| 3.7 | 11.2 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 3.7 | 44.7 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 3.6 | 21.8 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 3.6 | 82.2 | GO:0036442 | hydrogen-exporting ATPase activity(GO:0036442) |
| 3.5 | 10.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 3.5 | 14.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 3.5 | 10.6 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 3.5 | 60.0 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 3.5 | 10.6 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 3.5 | 34.7 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 3.5 | 13.8 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 3.4 | 10.3 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 3.4 | 20.5 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 3.4 | 27.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 3.4 | 13.5 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 3.4 | 13.4 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 3.3 | 40.1 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 3.2 | 9.6 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 3.2 | 15.9 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 3.1 | 28.2 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 3.1 | 12.4 | GO:0051373 | FATZ binding(GO:0051373) |
| 3.1 | 9.2 | GO:0102007 | lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007) |
| 3.0 | 27.4 | GO:0035877 | death effector domain binding(GO:0035877) |
| 3.0 | 89.2 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 2.9 | 11.7 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 2.9 | 26.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 2.9 | 80.3 | GO:0000049 | tRNA binding(GO:0000049) |
| 2.9 | 40.1 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 2.9 | 34.3 | GO:0030515 | snoRNA binding(GO:0030515) |
| 2.8 | 42.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 2.8 | 44.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 2.8 | 2.8 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 2.8 | 13.9 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 2.8 | 27.8 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 2.8 | 11.1 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 2.8 | 13.8 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 2.8 | 24.9 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 2.8 | 22.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 2.8 | 13.8 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 2.8 | 5.5 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 2.7 | 18.7 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 2.6 | 21.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 2.6 | 15.7 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 2.6 | 62.8 | GO:0005123 | death receptor binding(GO:0005123) |
| 2.6 | 112.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 2.5 | 122.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 2.5 | 30.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 2.5 | 7.6 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 2.5 | 10.1 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 2.5 | 39.5 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 2.5 | 41.9 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 2.4 | 2.4 | GO:0032407 | MutSalpha complex binding(GO:0032407) |
| 2.4 | 34.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 2.4 | 78.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 2.4 | 9.6 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 2.4 | 14.4 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 2.4 | 19.1 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 2.4 | 16.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 2.3 | 9.3 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 2.3 | 52.8 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 2.3 | 4.6 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 2.3 | 228.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 2.3 | 18.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.3 | 36.4 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 2.2 | 4.5 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 2.2 | 35.5 | GO:0005537 | mannose binding(GO:0005537) |
| 2.2 | 30.5 | GO:0048156 | tau protein binding(GO:0048156) |
| 2.2 | 188.5 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 2.2 | 13.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 2.1 | 4.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 2.1 | 12.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 2.1 | 74.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 2.1 | 12.6 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 2.1 | 68.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 2.1 | 10.3 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 2.1 | 158.7 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 2.1 | 22.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 2.0 | 76.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 2.0 | 6.0 | GO:0102008 | cytosolic dipeptidase activity(GO:0102008) |
| 1.9 | 5.8 | GO:0031896 | alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896) |
| 1.9 | 13.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 1.9 | 47.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 1.9 | 58.7 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 1.9 | 39.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 1.9 | 5.6 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 1.9 | 11.1 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 1.8 | 14.6 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 1.8 | 7.3 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.8 | 10.9 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 1.8 | 12.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 1.8 | 3.6 | GO:0070851 | growth factor receptor binding(GO:0070851) |
| 1.8 | 14.2 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 1.8 | 29.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 1.7 | 29.7 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 1.7 | 12.1 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.7 | 10.3 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 1.6 | 3.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 1.6 | 24.3 | GO:0019213 | deacetylase activity(GO:0019213) |
| 1.6 | 30.7 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 1.6 | 32.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 1.6 | 6.4 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 1.6 | 4.7 | GO:0048763 | HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763) |
| 1.5 | 18.4 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 1.5 | 4.6 | GO:0035198 | miRNA binding(GO:0035198) |
| 1.5 | 57.5 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 1.5 | 7.5 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 1.5 | 4.5 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 1.5 | 6.0 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 1.5 | 1.5 | GO:0016453 | C-acetyltransferase activity(GO:0016453) |
| 1.5 | 7.3 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 1.4 | 40.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 1.4 | 24.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 1.4 | 8.5 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.4 | 1.4 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 1.4 | 19.6 | GO:0016004 | phospholipase activator activity(GO:0016004) |
| 1.4 | 12.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 1.4 | 25.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 1.4 | 7.0 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 1.4 | 11.1 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 1.4 | 9.6 | GO:0043426 | MRF binding(GO:0043426) |
| 1.4 | 83.3 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 1.4 | 8.1 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 1.4 | 6.8 | GO:0045134 | uridine-diphosphatase activity(GO:0045134) |
| 1.3 | 18.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 1.3 | 3.9 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 1.3 | 9.2 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 1.3 | 3.9 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 1.3 | 2.5 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 1.3 | 7.6 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 1.3 | 8.8 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 1.3 | 3.8 | GO:0044549 | GTP cyclohydrolase binding(GO:0044549) |
| 1.3 | 78.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 1.2 | 97.1 | GO:0008565 | protein transporter activity(GO:0008565) |
| 1.2 | 421.7 | GO:0045296 | cadherin binding(GO:0045296) |
| 1.2 | 3.7 | GO:0034452 | dynactin binding(GO:0034452) |
| 1.2 | 3.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 1.2 | 15.7 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 1.2 | 2.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 1.2 | 4.6 | GO:0030760 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 1.1 | 14.9 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 1.1 | 41.9 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 1.1 | 12.0 | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity(GO:0008757) |
| 1.1 | 20.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 1.1 | 5.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 1.0 | 4.1 | GO:0008518 | reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350) |
| 1.0 | 10.2 | GO:0003680 | AT DNA binding(GO:0003680) |
| 1.0 | 12.2 | GO:0043274 | phospholipase binding(GO:0043274) |
| 1.0 | 16.0 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 1.0 | 10.0 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 1.0 | 6.9 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 1.0 | 151.2 | GO:0005178 | integrin binding(GO:0005178) |
| 0.9 | 56.8 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.9 | 3.7 | GO:0046790 | virion binding(GO:0046790) |
| 0.9 | 11.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.9 | 7.1 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.9 | 3.5 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.9 | 29.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.9 | 13.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.8 | 5.9 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.8 | 4.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.8 | 44.7 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.8 | 7.9 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.8 | 3.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.8 | 31.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.8 | 20.7 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.8 | 19.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.8 | 6.0 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.8 | 4.5 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.8 | 6.0 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.7 | 6.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.7 | 4.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
| 0.7 | 4.3 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.7 | 2.8 | GO:0030548 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.7 | 2.1 | GO:0004603 | phenylethanolamine N-methyltransferase activity(GO:0004603) |
| 0.7 | 8.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.7 | 8.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.7 | 2.1 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.7 | 4.1 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.7 | 2.7 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.7 | 10.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.6 | 21.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.6 | 4.4 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.6 | 7.4 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.6 | 5.5 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.6 | 9.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.6 | 3.0 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 0.6 | 11.7 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.6 | 4.6 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.6 | 16.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.6 | 0.6 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.6 | 12.7 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.5 | 33.1 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.5 | 2.7 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.5 | 2.7 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.5 | 13.7 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.5 | 9.0 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.5 | 4.6 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.5 | 6.0 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.5 | 8.0 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.5 | 8.5 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.5 | 1.5 | GO:1901611 | phosphatidylglycerol binding(GO:1901611) |
| 0.5 | 2.9 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.5 | 34.8 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.5 | 2.8 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.5 | 7.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.5 | 7.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.5 | 14.1 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.4 | 4.9 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.4 | 1.3 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.4 | 2.7 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.4 | 15.1 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.4 | 23.4 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.4 | 1.8 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.4 | 14.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.4 | 5.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.4 | 6.5 | GO:0005112 | Notch binding(GO:0005112) |
| 0.4 | 4.8 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.4 | 12.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.3 | 3.1 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.3 | 5.8 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.3 | 0.7 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.3 | 15.9 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
| 0.3 | 1.6 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.3 | 13.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.3 | 1.6 | GO:0004521 | endoribonuclease activity(GO:0004521) |
| 0.3 | 8.8 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 1.3 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.3 | 0.9 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.3 | 0.9 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.3 | 1.5 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.3 | 7.8 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859) |
| 0.3 | 3.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 3.9 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.2 | 1.7 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.2 | 2.7 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.2 | 2.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.2 | 0.8 | GO:0005113 | patched binding(GO:0005113) |
| 0.2 | 4.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 1.8 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.2 | 11.9 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 170.1 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 4.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 0.4 | GO:0015141 | thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141) |
| 0.2 | 0.7 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.2 | 23.4 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.2 | 13.8 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.2 | 1.3 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.2 | 14.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 1.7 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 4.7 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 10.1 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 2.0 | GO:0003712 | transcription cofactor activity(GO:0003712) |
| 0.1 | 1.0 | GO:0051430 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.5 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 0.7 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 1.2 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 0.6 | GO:0043142 | single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.1 | 0.7 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 5.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.7 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 1.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 3.5 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.1 | 0.3 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 1.3 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.1 | 0.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.6 | GO:0016829 | lyase activity(GO:0016829) |
| 0.0 | 0.7 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.7 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.0 | 0.1 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.0 | 0.3 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.0 | 0.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.1 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.0 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.0 | 0.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 21.8 | 544.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 13.2 | 224.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 11.1 | 1541.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 6.8 | 27.2 | PID IFNG PATHWAY | IFN-gamma pathway |
| 6.0 | 66.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 5.6 | 423.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 5.5 | 82.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 4.6 | 187.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 4.4 | 216.9 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 4.3 | 865.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 4.0 | 313.8 | PID E2F PATHWAY | E2F transcription factor network |
| 3.9 | 108.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 3.6 | 14.6 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 3.6 | 35.8 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 3.4 | 86.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 3.0 | 95.6 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 2.9 | 55.5 | ST STAT3 PATHWAY | STAT3 Pathway |
| 2.9 | 121.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 2.6 | 33.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 2.5 | 225.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 2.3 | 82.0 | PID BARD1 PATHWAY | BARD1 signaling events |
| 2.1 | 109.7 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 2.1 | 39.0 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 2.0 | 87.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 2.0 | 104.3 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 1.9 | 3.8 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 1.9 | 94.8 | PID CDC42 PATHWAY | CDC42 signaling events |
| 1.9 | 15.2 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 1.8 | 59.0 | PID INSULIN PATHWAY | Insulin Pathway |
| 1.8 | 168.1 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 1.8 | 17.8 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 1.7 | 79.6 | PID ATR PATHWAY | ATR signaling pathway |
| 1.7 | 5.0 | PID EPO PATHWAY | EPO signaling pathway |
| 1.6 | 109.7 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 1.6 | 91.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 1.6 | 83.3 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 1.6 | 75.0 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 1.6 | 39.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 1.5 | 32.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 1.4 | 21.5 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 1.4 | 30.9 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.4 | 113.3 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 1.4 | 23.8 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 1.4 | 73.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 1.3 | 56.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 1.3 | 11.7 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 1.3 | 20.7 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 1.3 | 9.0 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 1.2 | 26.4 | PID RHOA PATHWAY | RhoA signaling pathway |
| 1.2 | 13.2 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 1.2 | 34.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.1 | 20.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 1.1 | 7.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 1.1 | 11.2 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 1.1 | 17.3 | ST GAQ PATHWAY | G alpha q Pathway |
| 1.1 | 11.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 1.0 | 44.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.9 | 42.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.9 | 17.5 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.9 | 9.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.9 | 54.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.9 | 3.5 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.8 | 23.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.8 | 2.3 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.7 | 16.4 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.7 | 3.7 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.7 | 38.8 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.7 | 0.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.7 | 31.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.7 | 17.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.6 | 10.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.5 | 5.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.5 | 16.7 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.5 | 5.9 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.5 | 8.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.5 | 27.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.4 | 14.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.4 | 10.0 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.4 | 5.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.4 | 5.8 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.4 | 5.4 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.4 | 7.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.4 | 9.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.4 | 3.6 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.3 | 23.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.3 | 6.3 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.3 | 12.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.3 | 4.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.3 | 1.9 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.3 | 2.7 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.3 | 3.8 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 3.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.2 | 7.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.2 | 1.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 3.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 0.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 45.2 | 767.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 17.6 | 439.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 14.3 | 485.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 13.5 | 243.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 12.5 | 776.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 12.0 | 72.1 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 11.7 | 188.0 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 11.5 | 403.0 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 11.2 | 761.1 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 11.1 | 66.8 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 10.7 | 85.2 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 9.4 | 365.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 9.4 | 28.1 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 9.1 | 81.6 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 8.5 | 382.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 8.1 | 292.3 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 8.0 | 223.5 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 7.6 | 683.9 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 6.9 | 194.5 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 6.9 | 82.5 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 6.8 | 102.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 6.7 | 560.1 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 6.5 | 182.2 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 6.4 | 153.2 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 6.3 | 145.3 | REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | Genes involved in Assembly of the pre-replicative complex |
| 6.1 | 103.3 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 5.7 | 131.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 5.7 | 67.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 5.1 | 81.7 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 5.1 | 495.3 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 4.9 | 156.8 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 4.9 | 578.2 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
| 4.8 | 111.1 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 4.8 | 28.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 4.5 | 170.2 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 4.3 | 39.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 4.3 | 43.3 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 4.2 | 54.8 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 4.2 | 21.0 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 4.0 | 76.4 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
| 4.0 | 79.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 3.9 | 123.5 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 3.8 | 207.4 | REACTOME TRANSLATION | Genes involved in Translation |
| 3.8 | 148.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 3.7 | 98.9 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 3.6 | 61.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 3.6 | 60.9 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 3.5 | 56.8 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 3.3 | 85.2 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 3.2 | 169.7 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 3.2 | 80.0 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 3.1 | 144.8 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 3.1 | 102.2 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 3.1 | 49.2 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 3.0 | 57.4 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |
| 3.0 | 75.0 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 3.0 | 44.3 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 3.0 | 65.0 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 2.8 | 84.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 2.8 | 22.1 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 2.7 | 106.6 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 2.6 | 15.7 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
| 2.5 | 76.7 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 2.4 | 139.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 2.3 | 39.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 2.3 | 158.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 2.2 | 38.7 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 2.1 | 15.0 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 2.1 | 16.8 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 2.1 | 34.9 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 2.0 | 14.0 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 1.9 | 42.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 1.9 | 52.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 1.8 | 16.2 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 1.8 | 42.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 1.8 | 30.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 1.8 | 255.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.7 | 104.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 1.7 | 42.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 1.7 | 23.4 | REACTOME SIGNALING BY WNT | Genes involved in Signaling by Wnt |
| 1.7 | 50.0 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 1.6 | 36.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 1.6 | 16.0 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 1.6 | 15.7 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 1.6 | 18.9 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 1.6 | 53.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 1.6 | 10.9 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 1.5 | 52.2 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 1.5 | 11.9 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.5 | 62.0 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 1.4 | 138.0 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 1.4 | 54.7 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 1.4 | 30.4 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 1.4 | 9.7 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 1.4 | 22.1 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 1.3 | 138.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 1.3 | 9.0 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 1.2 | 66.4 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 1.2 | 4.7 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 1.1 | 23.0 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 1.1 | 25.0 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 1.1 | 42.2 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 1.0 | 27.1 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 1.0 | 4.9 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 1.0 | 10.6 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 1.0 | 13.4 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.9 | 3.8 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.9 | 14.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.9 | 16.3 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.9 | 16.3 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.9 | 56.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.9 | 7.0 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.8 | 5.9 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.8 | 5.0 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.8 | 16.8 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.8 | 20.8 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.8 | 6.3 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.7 | 78.6 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.7 | 87.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.7 | 7.9 | REACTOME OPSINS | Genes involved in Opsins |
| 0.7 | 71.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.7 | 15.8 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.6 | 41.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.6 | 10.2 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.5 | 18.5 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.5 | 5.9 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.5 | 1.5 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.5 | 2.9 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.5 | 14.3 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.5 | 9.7 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.5 | 29.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 3.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.4 | 29.4 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.4 | 3.8 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.4 | 22.5 | REACTOME PI METABOLISM | Genes involved in PI Metabolism |
| 0.4 | 7.5 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.4 | 23.3 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.3 | 4.1 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.3 | 3.7 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.3 | 24.1 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.3 | 23.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.3 | 1.3 | REACTOME MITOTIC M M G1 PHASES | Genes involved in Mitotic M-M/G1 phases |
| 0.2 | 2.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.2 | 0.9 | REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.2 | 5.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.2 | 3.9 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 3.5 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 13.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.2 | 4.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.0 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 1.5 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 2.0 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 2.7 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 0.4 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 1.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 1.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 1.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |