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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MYBL1

Z-value: 0.37

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Transcription factors associated with MYBL1

Gene Symbol Gene ID Gene Info
MYBL1
ENSG00000185697.12 MYB proto-oncogene like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYBL1hg19_v2_chr8_-_67525473_675255180.329.6e-07Click!

Activity profile of MYBL1 motif

Sorted Z-values of MYBL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_99127265 6.52 ENST00000306121.3
SNX7
sorting nexin 7
chr15_+_66797455 6.33 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr15_+_66797627 6.21 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr4_-_120988229 6.14 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr1_+_99127225 5.66 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr19_-_55919087 5.56 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S
ubiquitin-conjugating enzyme E2S
chr1_-_211848899 4.90 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr1_-_197115818 4.74 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr7_+_12726474 4.32 ENST00000396662.1
ENST00000356797.3
ENST00000396664.2
ARL4A
ADP-ribosylation factor-like 4A
chr3_+_160117418 3.66 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr14_-_58893832 3.61 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_-_43855444 3.50 ENST00000372455.4
MED8
mediator complex subunit 8
chr18_+_20513782 3.46 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
RBBP8
retinoblastoma binding protein 8
chr6_+_42847348 3.45 ENST00000493763.1
ENST00000304734.5
RPL7L1
ribosomal protein L7-like 1
chr15_-_63449663 3.42 ENST00000439025.1
RPS27L
ribosomal protein S27-like
chr3_-_148804275 3.39 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr8_-_25315905 3.33 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chrX_+_114795489 3.25 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
PLS3
plastin 3
chr14_-_58894223 3.20 ENST00000555593.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_+_18433840 3.17 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr1_-_68962805 3.10 ENST00000370966.5
DEPDC1
DEP domain containing 1
chr3_+_139063372 3.07 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr19_-_12595586 2.96 ENST00000397732.3
ZNF709
zinc finger protein 709
chr3_+_157154578 2.96 ENST00000295927.3
PTX3
pentraxin 3, long
chr13_+_114567131 2.94 ENST00000608651.1
GAS6-AS2
GAS6 antisense RNA 2 (head to head)
chr2_+_69969106 2.86 ENST00000409920.1
ENST00000394295.4
ENST00000536030.1
ANXA4
annexin A4
chr7_-_148581360 2.81 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr11_+_20409070 2.81 ENST00000331079.6
PRMT3
protein arginine methyltransferase 3
chr2_+_122513109 2.80 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr5_+_10250328 2.69 ENST00000515390.1
CCT5
chaperonin containing TCP1, subunit 5 (epsilon)
chr14_+_57857262 2.63 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr9_-_21995249 2.57 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr16_+_89696692 2.52 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr14_-_105420241 2.48 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr17_-_9479128 2.44 ENST00000574431.1
STX8
syntaxin 8
chr6_-_56707943 2.42 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr7_+_16685756 2.40 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
BZW2
basic leucine zipper and W2 domains 2
chr2_-_44223138 2.38 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr9_-_95056010 2.37 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr22_-_42342692 2.36 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr7_+_73106926 2.35 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr4_+_17812525 2.29 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr12_-_120765565 2.27 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr14_-_58894332 2.27 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr10_+_5135981 2.23 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr3_-_51975942 2.23 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr8_+_101162812 2.23 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr3_+_171758344 2.20 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr12_+_69753448 2.18 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS4
YEATS domain containing 4
chr17_-_40075197 2.18 ENST00000590770.1
ENST00000590151.1
ACLY
ATP citrate lyase
chr6_+_36562132 2.16 ENST00000373715.6
ENST00000339436.7
SRSF3
serine/arginine-rich splicing factor 3
chr16_-_75498553 2.15 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr17_+_73201754 2.13 ENST00000583569.1
ENST00000245544.4
ENST00000579324.1
ENST00000541827.1
ENST00000579298.1
ENST00000447371.2
NUP85
nucleoporin 85kDa
chr1_-_227505289 2.11 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_233086326 2.07 ENST00000366628.5
ENST00000366627.4
NTPCR
nucleoside-triphosphatase, cancer-related
chr20_+_52824367 2.07 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr16_+_56485402 2.06 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr11_-_27723158 2.03 ENST00000395980.2
BDNF
brain-derived neurotrophic factor
chr7_-_16685422 2.02 ENST00000306999.2
ANKMY2
ankyrin repeat and MYND domain containing 2
chr2_-_190044480 1.99 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr17_-_40075219 1.98 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ACLY
ATP citrate lyase
chr8_+_104310661 1.98 ENST00000522566.1
FZD6
frizzled family receptor 6
chr10_+_60145155 1.97 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr12_-_57081940 1.94 ENST00000436399.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr15_+_89787180 1.91 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr17_-_30668887 1.89 ENST00000581747.1
ENST00000583334.1
ENST00000580558.1
C17orf75
chromosome 17 open reading frame 75
chr22_-_42343117 1.88 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr15_-_55489097 1.87 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr18_-_71959159 1.84 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr16_-_56485257 1.84 ENST00000300291.5
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr2_+_113033164 1.78 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr7_-_76255444 1.77 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr17_+_48133459 1.76 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr8_-_80942467 1.75 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr9_-_21994597 1.70 ENST00000579755.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr17_-_30669138 1.70 ENST00000225805.4
ENST00000577809.1
C17orf75
chromosome 17 open reading frame 75
chr1_+_145883868 1.68 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chrX_-_104465358 1.68 ENST00000372578.3
ENST00000372575.1
ENST00000413579.1
TEX13A
testis expressed 13A
chr4_+_123747834 1.67 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr6_-_43027105 1.67 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr2_-_191115229 1.64 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr7_+_7222233 1.64 ENST00000436587.2
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_193074504 1.61 ENST00000367439.3
GLRX2
glutaredoxin 2
chr10_-_35379524 1.60 ENST00000374751.3
ENST00000374742.1
ENST00000602371.1
CUL2
cullin 2
chr3_+_141144954 1.56 ENST00000441582.2
ENST00000321464.5
ZBTB38
zinc finger and BTB domain containing 38
chr10_+_43278217 1.55 ENST00000374518.5
BMS1
BMS1 ribosome biogenesis factor
chr9_-_21994344 1.55 ENST00000530628.2
ENST00000361570.3
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr16_-_14724057 1.54 ENST00000539279.1
ENST00000420015.2
ENST00000437198.2
PARN
poly(A)-specific ribonuclease
chr22_-_36220420 1.49 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_-_124569991 1.45 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
POT1
protection of telomeres 1
chr5_-_147211190 1.44 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr1_-_245027833 1.44 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_-_40006357 1.42 ENST00000505747.1
THUMPD2
THUMP domain containing 2
chr11_+_18417813 1.42 ENST00000540430.1
ENST00000379412.5
LDHA
lactate dehydrogenase A
chr15_-_66797172 1.42 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
RPL4
ribosomal protein L4
chr5_-_147211226 1.41 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr4_+_123747979 1.40 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr11_-_62609281 1.39 ENST00000525239.1
ENST00000538098.2
WDR74
WD repeat domain 74
chr17_-_1303462 1.38 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chrX_-_140673133 1.35 ENST00000370519.3
SPANXA1
sperm protein associated with the nucleus, X-linked, family member A1
chr22_+_19118321 1.33 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chr14_+_51706886 1.30 ENST00000457354.2
TMX1
thioredoxin-related transmembrane protein 1
chr5_-_146833485 1.26 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr1_-_43855479 1.22 ENST00000290663.6
ENST00000372457.4
MED8
mediator complex subunit 8
chr8_-_141774467 1.21 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr12_-_76478446 1.21 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_172502336 1.19 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr16_+_56642489 1.19 ENST00000561491.1
MT2A
metallothionein 2A
chr1_+_186344945 1.18 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr12_+_49717019 1.17 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP
trophinin associated protein
chr3_+_37034823 1.17 ENST00000231790.2
ENST00000456676.2
MLH1
mutL homolog 1
chr17_+_685513 1.15 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr1_-_227505826 1.13 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr1_+_171217677 1.12 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr10_+_76969909 1.09 ENST00000298468.5
ENST00000543351.1
VDAC2
voltage-dependent anion channel 2
chr4_+_147096837 1.09 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_112709804 1.08 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr19_+_11466167 1.07 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr3_-_100120223 1.07 ENST00000284320.5
TOMM70A
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr2_+_204193101 1.06 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2
abl-interactor 2
chr2_-_86564776 1.06 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chrX_-_135962876 1.06 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr10_+_31608054 1.05 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr7_+_23221438 1.04 ENST00000258742.5
NUPL2
nucleoporin like 2
chr7_-_18067478 1.02 ENST00000506618.2
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr13_+_45694583 1.02 ENST00000340473.6
GTF2F2
general transcription factor IIF, polypeptide 2, 30kDa
chr11_-_104840093 1.01 ENST00000417440.2
ENST00000444739.2
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr5_-_40835303 1.01 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37
ribosomal protein L37
chr4_-_2965052 0.98 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14
NOP14 nucleolar protein
chr8_-_117768023 0.95 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr13_-_114567034 0.95 ENST00000327773.6
ENST00000357389.3
GAS6
growth arrest-specific 6
chr13_-_37633567 0.94 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr2_-_55646957 0.93 ENST00000263630.8
CCDC88A
coiled-coil domain containing 88A
chr1_+_211499957 0.91 ENST00000336184.2
TRAF5
TNF receptor-associated factor 5
chr2_-_55647057 0.89 ENST00000436346.1
CCDC88A
coiled-coil domain containing 88A
chr4_+_166248775 0.88 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr17_-_36981556 0.86 ENST00000536127.1
ENST00000225428.5
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr1_-_159869912 0.86 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr6_+_74104471 0.86 ENST00000370336.4
DDX43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr10_+_124768482 0.86 ENST00000368869.4
ENST00000358776.4
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr3_+_112709755 0.84 ENST00000383678.2
GTPBP8
GTP-binding protein 8 (putative)
chr7_+_23221613 0.82 ENST00000410002.3
ENST00000413919.1
NUPL2
nucleoporin like 2
chr13_-_37633743 0.80 ENST00000497318.1
ENST00000475892.1
ENST00000356185.3
ENST00000350612.6
ENST00000542180.1
ENST00000360252.4
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr7_+_2394445 0.79 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
EIF3B
eukaryotic translation initiation factor 3, subunit B
chr11_-_78285804 0.79 ENST00000281038.5
ENST00000529571.1
NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr19_-_47734448 0.77 ENST00000439096.2
BBC3
BCL2 binding component 3
chr9_-_21305312 0.77 ENST00000259555.4
IFNA5
interferon, alpha 5
chr3_+_49977440 0.77 ENST00000442092.1
ENST00000266022.4
ENST00000443081.1
RBM6
RNA binding motif protein 6
chr19_+_11466062 0.76 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr2_-_70781087 0.76 ENST00000394241.3
ENST00000295400.6
TGFA
transforming growth factor, alpha
chr12_+_133758115 0.74 ENST00000541009.2
ENST00000592241.1
ZNF268
zinc finger protein 268
chr4_+_17616253 0.74 ENST00000237380.7
MED28
mediator complex subunit 28
chr17_-_685559 0.74 ENST00000301329.6
GLOD4
glyoxalase domain containing 4
chr17_-_42019836 0.73 ENST00000225992.3
PPY
pancreatic polypeptide
chr21_-_15755446 0.73 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr12_-_122710556 0.73 ENST00000446652.1
ENST00000541273.1
ENST00000353548.6
ENST00000267169.6
ENST00000464942.2
DIABLO
diablo, IAP-binding mitochondrial protein
chr20_-_23969416 0.72 ENST00000335694.4
GGTLC1
gamma-glutamyltransferase light chain 1
chr12_+_120933859 0.71 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr21_-_33984865 0.70 ENST00000458138.1
C21orf59
chromosome 21 open reading frame 59
chr17_-_56769382 0.70 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr18_-_44497308 0.69 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
PIAS2
protein inhibitor of activated STAT, 2
chr22_+_22516550 0.69 ENST00000390284.2
IGLV4-60
immunoglobulin lambda variable 4-60
chr6_+_35227449 0.68 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr15_-_25684110 0.68 ENST00000232165.3
UBE3A
ubiquitin protein ligase E3A
chr21_-_33984888 0.67 ENST00000382549.4
ENST00000540881.1
C21orf59
chromosome 21 open reading frame 59
chr1_+_97187318 0.67 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr12_-_66563728 0.67 ENST00000286424.7
ENST00000556010.1
ENST00000398033.4
TMBIM4
transmembrane BAX inhibitor motif containing 4
chr19_+_38826415 0.65 ENST00000410018.1
ENST00000409235.3
CATSPERG
catsper channel auxiliary subunit gamma
chr10_+_71561630 0.65 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr1_+_27248203 0.65 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr14_+_21387491 0.64 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr16_-_29934558 0.63 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr3_+_49977490 0.63 ENST00000539992.1
RBM6
RNA binding motif protein 6
chr12_-_47219733 0.63 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4
solute carrier family 38, member 4
chr16_-_20753114 0.63 ENST00000396083.2
THUMPD1
THUMP domain containing 1
chr16_-_22385901 0.63 ENST00000268383.2
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr1_+_92414928 0.62 ENST00000362005.3
ENST00000370389.2
ENST00000399546.2
ENST00000423434.1
ENST00000394530.3
ENST00000440509.1
BRDT
bromodomain, testis-specific
chr17_-_685493 0.62 ENST00000536578.1
ENST00000301328.5
ENST00000576419.1
GLOD4
glyoxalase domain containing 4
chr12_-_76478686 0.61 ENST00000261182.8
NAP1L1
nucleosome assembly protein 1-like 1
chr6_-_31510181 0.60 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chrX_-_74376108 0.60 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr4_+_79567362 0.56 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr3_+_49977523 0.56 ENST00000422955.1
RBM6
RNA binding motif protein 6
chr7_+_99102573 0.56 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr2_-_208489707 0.55 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
METTL21A
methyltransferase like 21A
chr1_+_236686875 0.55 ENST00000366584.4
LGALS8
lectin, galactoside-binding, soluble, 8
chr14_-_50101931 0.55 ENST00000298292.8
ENST00000406043.3
DNAAF2
dynein, axonemal, assembly factor 2
chr21_-_33985127 0.54 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr15_+_48624300 0.54 ENST00000455976.2
ENST00000559540.1
DUT
deoxyuridine triphosphatase
chr1_+_211500129 0.53 ENST00000427925.2
ENST00000261464.5
TRAF5
TNF receptor-associated factor 5
chr1_-_11159887 0.53 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
EXOSC10
exosome component 10
chr11_-_47600549 0.52 ENST00000430070.2
KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr4_-_140098339 0.52 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr20_+_34802295 0.51 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_+_171217622 0.51 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr11_+_122753391 0.50 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr1_-_202129105 0.50 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_+_52051171 0.49 ENST00000340057.1
IL17A
interleukin 17A
chr4_+_79472673 0.49 ENST00000264908.6
ANXA3
annexin A3
chr8_+_50824233 0.48 ENST00000522124.1
SNTG1
syntrophin, gamma 1

Network of associatons between targets according to the STRING database.

First level regulatory network of MYBL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.0 9.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.0 4.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.9 2.8 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.8 2.5 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.8 2.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.8 4.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.7 2.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.7 6.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.7 2.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.6 2.4 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.6 3.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.6 2.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 5.8 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.5 3.2 GO:0019249 lactate biosynthetic process(GO:0019249)
0.5 2.0 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.5 2.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.5 3.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 2.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.5 2.8 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5 1.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.5 1.4 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.5 3.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.5 1.4 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.5 1.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 3.1 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.4 2.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 2.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.4 1.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4 1.2 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.3 1.6 GO:0006574 valine catabolic process(GO:0006574)
0.3 2.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 0.9 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159) renal albumin absorption(GO:0097018) oligodendrocyte apoptotic process(GO:0097252) regulation of renal albumin absorption(GO:2000532)
0.3 2.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 1.8 GO:0035803 egg coat formation(GO:0035803)
0.3 3.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 2.8 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 4.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 1.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 0.7 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.2 2.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 4.5 GO:0051764 actin crosslink formation(GO:0051764)
0.2 2.7 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 1.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 1.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.2 3.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.6 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.5 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.2 0.5 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.2 0.5 GO:0050854 regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of B cell receptor signaling pathway(GO:0050855)
0.2 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 1.6 GO:0042262 DNA protection(GO:0042262)
0.2 1.4 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.5 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 3.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.5 GO:0051096 telomere assembly(GO:0032202) positive regulation of helicase activity(GO:0051096)
0.1 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.3 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 1.5 GO:0090671 RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.1 2.1 GO:0019511 regulation of translational termination(GO:0006449) peptidyl-proline hydroxylation(GO:0019511)
0.1 1.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 4.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 1.0 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.7 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.6 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 14.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 4.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.4 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.8 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 6.5 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 1.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 2.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:0060301 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 2.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 2.1 GO:0016311 dephosphorylation(GO:0016311)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.5 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.6 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.7 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.6 GO:0015886 heme transport(GO:0015886)
0.1 1.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.7 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 2.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.7 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.9 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.7 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 3.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.8 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 1.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.6 GO:0000154 rRNA modification(GO:0000154)
0.0 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 2.1 GO:0006457 protein folding(GO:0006457)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:0032098 regulation of appetite(GO:0032098)
0.0 2.0 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.8 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 7.6 GO:0016050 vesicle organization(GO:0016050)
0.0 0.4 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 1.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.2 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:1990423 RZZ complex(GO:1990423)
2.3 9.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.7 2.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.7 4.7 GO:0036449 microtubule minus-end(GO:0036449)
0.7 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.6 GO:0031417 NatC complex(GO:0031417)
0.6 2.4 GO:0031673 H zone(GO:0031673)
0.6 6.0 GO:0000796 condensin complex(GO:0000796)
0.6 1.8 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.5 5.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 1.2 GO:0005715 late recombination nodule(GO:0005715)
0.3 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 1.0 GO:0030689 Noc complex(GO:0030689)
0.3 1.6 GO:0030891 VCB complex(GO:0030891)
0.3 2.1 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.8 GO:0042382 paraspeckles(GO:0042382)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 2.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 1.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 5.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 2.8 GO:0045120 pronucleus(GO:0045120)
0.2 4.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 1.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 0.7 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2 3.2 GO:0042641 actomyosin(GO:0042641)
0.2 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.2 2.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.7 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.5 GO:0070187 telosome(GO:0070187)
0.1 15.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 1.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 2.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 5.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 3.3 GO:0016592 mediator complex(GO:0016592)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.9 GO:0030686 90S preribosome(GO:0030686)
0.1 2.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 2.9 GO:0043034 costamere(GO:0043034)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 6.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.1 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 5.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 4.5 GO:0005840 ribosome(GO:0005840)
0.0 4.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 3.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.4 GO:0031201 SNARE complex(GO:0031201)
0.0 4.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.7 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 2.3 GO:0031514 motile cilium(GO:0031514)
0.0 9.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.8 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 5.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 2.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.7 2.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.7 2.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.7 4.6 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.6 3.7 GO:0034511 U3 snoRNA binding(GO:0034511)
0.6 2.2 GO:0047023 enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4 2.0 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.4 3.0 GO:0001849 complement component C1q binding(GO:0001849)
0.4 2.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.3 5.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.6 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.3 2.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 2.8 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 3.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 2.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 2.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 2.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 2.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 3.4 GO:0008494 translation activator activity(GO:0008494)
0.2 1.8 GO:0032190 acrosin binding(GO:0032190)
0.2 1.4 GO:0050815 phosphoserine binding(GO:0050815)
0.2 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.2 3.3 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.1 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.2 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 3.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.5 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.1 2.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.1 GO:0015288 porin activity(GO:0015288)
0.1 1.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 3.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 2.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.6 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 3.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1 1.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.2 GO:0046870 cadmium ion binding(GO:0046870)
0.1 1.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.1 1.4 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 9.4 GO:0051087 chaperone binding(GO:0051087)
0.1 0.6 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 2.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.0 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 10.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 4.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 9.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 3.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 4.7 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 4.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 3.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 4.1 PID AURORA B PATHWAY Aurora B signaling
0.1 3.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 5.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 4.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 3.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 17.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 10.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 2.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 4.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 3.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 5.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 2.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 2.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 5.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism