Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for MYBL1
Z-value: 0.37
Motif logo
Transcription factors associated with MYBL1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYBL1 | hg19_v2_chr8_-_67525473_67525518 | 0.32 | 9.6e-07 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYBL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.0 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 1.0 | 9.1 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 7.6 | GO:0016050 | vesicle organization(GO:0016050) |
| 0.1 | 6.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.7 | 6.1 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.5 | 5.8 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 1.9 | 5.6 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 1.0 | 4.9 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.8 | 4.7 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.2 | 4.5 | GO:0051764 | actin crosslink formation(GO:0051764) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 3.1 | 12.5 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.0 | 9.3 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
| 2.3 | 9.1 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.1 | 6.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.6 | 6.0 | GO:0000796 | condensin complex(GO:0000796) |
| 0.5 | 5.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.2 | 5.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 5.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 5.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 9.4 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 9.0 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.3 | 5.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 4.9 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 4.7 | GO:0004386 | helicase activity(GO:0004386) |
| 0.7 | 4.6 | GO:0004459 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 0.0 | 4.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.8 | 4.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.6 | 3.7 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.8 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 5.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 5.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 4.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 4.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 3.7 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.1 | 3.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 3.2 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 3.0 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 17.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 10.4 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.3 | 9.2 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.1 | 5.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 5.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 4.8 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.2 | 3.1 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 3.0 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 3.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 2.8 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |