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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for MZF1

Z-value: 0.07

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Transcription factors associated with MZF1

Gene Symbol Gene ID Gene Info
MZF1
ENSG00000099326.4 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MZF1hg19_v2_chr19_-_59084647_590847210.429.6e-11Click!

Activity profile of MZF1 motif

Sorted Z-values of MZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_61765315 24.96 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_+_4618734 24.50 ENST00000571206.1
ARRB2
arrestin, beta 2
chr4_-_84035905 20.71 ENST00000311507.4
PLAC8
placenta-specific 8
chr4_-_84035868 19.47 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr17_-_47841485 19.23 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr16_+_69958887 19.20 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr11_-_46142615 17.57 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr12_-_15114603 15.95 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_46142948 15.85 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr1_-_153518270 15.11 ENST00000354332.4
ENST00000368716.4
S100A4
S100 calcium binding protein A4
chr14_+_75745477 14.89 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr19_-_39826639 14.52 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr17_+_4613776 14.00 ENST00000269260.2
ARRB2
arrestin, beta 2
chr17_+_4613918 13.68 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr12_-_15114492 13.44 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_137688285 13.23 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chrX_-_135849484 13.14 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr6_-_86352982 12.52 ENST00000369622.3
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_32157947 12.16 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr2_+_219264466 12.12 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_+_38278826 12.05 ENST00000577454.1
ENST00000578648.1
ENST00000579565.1
MSL1
male-specific lethal 1 homolog (Drosophila)
chr16_-_28222797 11.46 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr6_-_42016385 11.05 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr6_+_32936353 11.03 ENST00000374825.4
BRD2
bromodomain containing 2
chr1_-_150208498 10.57 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_-_32160622 10.56 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chrX_-_70474499 10.34 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr19_-_39108568 10.30 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr12_-_7077125 10.23 ENST00000545555.2
PHB2
prohibitin 2
chr19_+_35645817 10.17 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645618 10.16 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr9_+_131452239 9.72 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr5_+_49962495 9.57 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_-_81046841 9.47 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr2_-_61697862 9.42 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr1_-_150208412 9.25 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_4382917 9.22 ENST00000261254.3
CCND2
cyclin D2
chr14_-_23285011 9.17 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_+_123095155 9.02 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr1_+_27022839 8.96 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr1_+_209941827 8.79 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr1_+_145516560 8.74 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr6_+_32938692 8.70 ENST00000443797.2
BRD2
bromodomain containing 2
chr19_+_16435625 8.60 ENST00000248071.5
ENST00000592003.1
KLF2
Kruppel-like factor 2
chr1_+_145516252 8.56 ENST00000369306.3
PEX11B
peroxisomal biogenesis factor 11 beta
chr8_+_41347915 8.48 ENST00000518270.1
ENST00000520817.1
GOLGA7
golgin A7
chr8_+_41348173 8.42 ENST00000357743.4
GOLGA7
golgin A7
chr5_-_81046922 8.39 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr13_-_31039375 8.37 ENST00000399494.1
HMGB1
high mobility group box 1
chr6_+_37137939 8.37 ENST00000373509.5
PIM1
pim-1 oncogene
chr14_-_23285069 8.19 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_+_41348072 8.11 ENST00000405786.2
GOLGA7
golgin A7
chr11_-_64512273 8.04 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_64512803 8.02 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr3_-_50378343 8.00 ENST00000359365.4
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chrX_-_47518498 7.99 ENST00000335890.2
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr5_+_32531893 7.95 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr14_+_50359773 7.95 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr14_+_75746340 7.93 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr17_+_7210898 7.92 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr14_+_23791159 7.90 ENST00000557702.1
PABPN1
poly(A) binding protein, nuclear 1
chr4_+_174089904 7.88 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr12_-_123011536 7.88 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr9_-_86595105 7.83 ENST00000457156.1
ENST00000360384.5
ENST00000376263.3
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr19_-_41859814 7.80 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr17_-_48943706 7.76 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr3_-_50378235 7.70 ENST00000357043.2
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr1_-_153363452 7.64 ENST00000368732.1
ENST00000368733.3
S100A8
S100 calcium binding protein A8
chr5_-_81046904 7.61 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr1_+_155658849 7.56 ENST00000368336.5
ENST00000343043.3
ENST00000421487.2
ENST00000535183.1
ENST00000465375.1
ENST00000470830.1
DAP3
death associated protein 3
chr5_-_169725231 7.53 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_50344289 7.50 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr14_-_35344093 7.48 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr1_-_154580616 7.35 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chrX_+_123095546 7.30 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr6_+_32944119 6.99 ENST00000606059.1
BRD2
bromodomain containing 2
chr5_-_131826457 6.92 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chrX_-_70474910 6.87 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr9_+_100745615 6.87 ENST00000339399.4
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr3_+_133292574 6.84 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr17_-_4852332 6.80 ENST00000572383.1
PFN1
profilin 1
chr14_+_102228123 6.79 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_150208363 6.78 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_21610797 6.76 ENST00000358154.3
METTL9
methyltransferase like 9
chr10_-_12084770 6.73 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr1_-_155658085 6.73 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr1_-_226924980 6.71 ENST00000272117.3
ITPKB
inositol-trisphosphate 3-kinase B
chr17_-_7154984 6.71 ENST00000574322.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr17_-_20370847 6.69 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr19_-_39108643 6.67 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr1_+_113161778 6.63 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chrX_-_47518527 6.62 ENST00000333119.3
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr17_+_65373531 6.62 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr5_+_49963239 6.61 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_-_53018654 6.51 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr22_-_32058166 6.46 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr1_+_174769006 6.35 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr2_-_175499294 6.34 ENST00000392547.2
WIPF1
WAS/WASL interacting protein family, member 1
chr19_-_19754404 6.34 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr6_+_32940436 6.34 ENST00000395287.1
BRD2
bromodomain containing 2
chr1_-_151032040 6.27 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr2_+_30454390 6.26 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr9_-_130213652 6.23 ENST00000536368.1
ENST00000361436.5
RPL12
ribosomal protein L12
chr11_-_76091986 6.13 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr19_-_39108552 6.12 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr14_+_23776167 6.11 ENST00000554635.1
ENST00000557008.1
BCL2L2
BCL2L2-PABPN1
BCL2-like 2
BCL2L2-PABPN1 readthrough
chr6_+_32938665 6.06 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chrX_-_119694538 6.02 ENST00000371322.5
CUL4B
cullin 4B
chr1_-_150208320 6.02 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_2802623 6.02 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr10_-_88281494 5.89 ENST00000298767.5
WAPAL
wings apart-like homolog (Drosophila)
chr11_-_64512469 5.88 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_+_94542459 5.87 ENST00000258526.4
PLXNC1
plexin C1
chr8_+_123793633 5.85 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr14_+_23776024 5.85 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr3_+_150321068 5.84 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT
Selenoprotein T
chr20_+_31407692 5.80 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr1_-_155658260 5.76 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
YY1AP1
YY1 associated protein 1
chr4_-_77997126 5.74 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
CCNI
cyclin I
chr15_+_75074410 5.71 ENST00000439220.2
CSK
c-src tyrosine kinase
chr10_-_120840309 5.70 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr4_+_129730779 5.69 ENST00000226319.6
PHF17
jade family PHD finger 1
chr1_-_183560011 5.63 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr3_+_196466710 5.62 ENST00000327134.3
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr20_-_45981138 5.59 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr17_-_65241281 5.52 ENST00000358691.5
ENST00000580168.1
HELZ
helicase with zinc finger
chr8_+_29953163 5.49 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr13_-_31040060 5.46 ENST00000326004.4
ENST00000341423.5
HMGB1
high mobility group box 1
chr4_+_129730947 5.44 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr11_-_2323290 5.43 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr6_-_24721054 5.42 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr6_+_42749759 5.38 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr1_+_211433275 5.35 ENST00000367005.4
RCOR3
REST corepressor 3
chr1_-_155658518 5.35 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
YY1AP1
YY1 associated protein 1
chr3_-_150320937 5.34 ENST00000479209.1
SERP1
stress-associated endoplasmic reticulum protein 1
chr5_+_133861790 5.32 ENST00000395003.1
PHF15
jade family PHD finger 2
chr14_-_64010046 5.32 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr17_-_7590745 5.24 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr2_-_60780607 5.22 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_26241325 5.18 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chr16_+_21610879 5.16 ENST00000396014.4
METTL9
methyltransferase like 9
chr19_-_50432782 5.16 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr17_-_56065484 5.11 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr1_+_27022485 5.08 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr13_-_52027134 4.98 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr2_-_48132924 4.98 ENST00000403359.3
FBXO11
F-box protein 11
chr6_-_86352642 4.96 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chrX_-_129244655 4.96 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr1_+_110163202 4.95 ENST00000531203.1
ENST00000256578.3
AMPD2
adenosine monophosphate deaminase 2
chr10_-_99094458 4.94 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr4_-_183838596 4.91 ENST00000508994.1
ENST00000512766.1
DCTD
dCMP deaminase
chr6_-_137113604 4.89 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr17_-_27418537 4.88 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr16_+_718086 4.87 ENST00000315082.4
ENST00000563134.1
RHOT2
ras homolog family member T2
chr10_+_104535994 4.87 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr12_-_57522813 4.83 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_155658766 4.81 ENST00000295566.4
ENST00000368330.2
YY1AP1
YY1 associated protein 1
chr5_+_115177178 4.78 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr19_-_47220335 4.75 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2
protein kinase D2
chr17_-_7155274 4.74 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr12_-_123011476 4.73 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr14_+_23790690 4.68 ENST00000556821.1
PABPN1
poly(A) binding protein, nuclear 1
chr7_+_114562172 4.65 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr2_-_60780702 4.52 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr8_+_29952914 4.51 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr3_-_182698381 4.50 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr10_+_31608054 4.48 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr14_+_92980111 4.44 ENST00000216487.7
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr1_-_150208291 4.44 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_167906277 4.43 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr7_+_26241310 4.43 ENST00000396386.2
CBX3
chromobox homolog 3
chr6_-_79944336 4.42 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr4_-_183838372 4.42 ENST00000503820.1
ENST00000503988.1
DCTD
dCMP deaminase
chr2_+_178077477 4.41 ENST00000411529.2
ENST00000435711.1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr1_-_23670813 4.40 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr14_-_65569186 4.38 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MAX
MYC associated factor X
chr9_+_2015335 4.36 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_103880209 4.34 ENST00000425280.1
LDB1
LIM domain binding 1
chr17_+_30264014 4.34 ENST00000322652.5
ENST00000580398.1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
chr18_-_53255766 4.34 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr10_+_70091847 4.30 ENST00000441000.2
ENST00000354695.5
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr17_+_43299156 4.29 ENST00000331495.3
FMNL1
formin-like 1
chr11_+_10476851 4.29 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr10_+_114710211 4.29 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_23670817 4.26 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr19_-_33166045 4.25 ENST00000586693.3
ENST00000587352.1
ENST00000586463.1
ENST00000306065.4
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr11_+_66384053 4.24 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
RBM14
RBM4
RBM14-RBM4
RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr1_-_155224751 4.23 ENST00000350210.2
ENST00000368368.3
FAM189B
family with sequence similarity 189, member B
chr1_-_183559693 4.21 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr9_-_35650900 4.21 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr6_+_30297306 4.17 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr19_-_2050852 4.08 ENST00000541165.1
ENST00000591601.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr10_+_21823079 4.08 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_+_182321925 4.08 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr6_+_111195973 4.04 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr16_+_88872176 4.03 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr1_-_23670752 4.02 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chrX_+_109245863 3.98 ENST00000372072.3
TMEM164
transmembrane protein 164
chr14_+_90864504 3.97 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_-_151431909 3.96 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain

Network of associatons between targets according to the STRING database.

First level regulatory network of MZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 52.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
7.3 29.4 GO:0071461 cellular response to redox state(GO:0071461)
6.8 20.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
5.4 16.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
4.3 17.3 GO:0044375 regulation of peroxisome size(GO:0044375)
4.3 12.9 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
3.6 17.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.6 25.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.5 13.8 GO:0002840 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
3.4 3.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
3.0 18.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
3.0 23.9 GO:0001661 conditioned taste aversion(GO:0001661)
2.9 17.4 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
2.9 8.6 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.8 14.0 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
2.5 40.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.5 17.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.5 7.4 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
2.2 15.7 GO:0006226 dUMP biosynthetic process(GO:0006226)
2.1 8.6 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.1 14.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
2.1 16.6 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
2.0 7.8 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
2.0 7.8 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.9 5.7 GO:0002188 formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
1.8 5.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.7 5.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oxidative stress-induced premature senescence(GO:0090403) oligodendrocyte apoptotic process(GO:0097252)
1.7 6.9 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.7 18.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.7 10.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.6 6.3 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
1.5 8.9 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.5 13.2 GO:0072718 response to cisplatin(GO:0072718)
1.4 7.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.4 5.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.3 4.0 GO:0006597 spermine biosynthetic process(GO:0006597)
1.3 4.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
1.3 4.0 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.3 3.9 GO:0002084 protein depalmitoylation(GO:0002084)
1.3 2.6 GO:0061010 gall bladder development(GO:0061010)
1.3 3.8 GO:2001160 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
1.3 6.3 GO:2000035 positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035)
1.2 12.4 GO:0032264 IMP salvage(GO:0032264)
1.2 8.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.2 3.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
1.1 5.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.1 7.6 GO:0032119 sequestering of zinc ion(GO:0032119)
1.1 2.2 GO:0002572 pro-T cell differentiation(GO:0002572)
1.1 4.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.1 5.3 GO:0010587 miRNA catabolic process(GO:0010587)
1.0 23.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.0 4.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.0 6.7 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.9 5.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.9 5.5 GO:0072553 terminal button organization(GO:0072553)
0.9 45.9 GO:0043486 histone exchange(GO:0043486)
0.9 2.7 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.9 3.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.9 1.7 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.9 6.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.8 9.3 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.8 10.7 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.8 3.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.8 4.9 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.8 4.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.8 3.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.8 2.4 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.8 3.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.8 3.8 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.8 12.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.7 17.8 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.7 12.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.7 5.0 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.7 12.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.7 2.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.7 1.4 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.7 2.7 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.7 10.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6 3.9 GO:0044351 macropinocytosis(GO:0044351)
0.6 1.9 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.6 2.5 GO:0030242 pexophagy(GO:0030242)
0.6 2.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.6 4.9 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.6 2.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.6 11.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.5 4.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.5 3.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.5 47.3 GO:0006334 nucleosome assembly(GO:0006334)
0.5 2.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.5 2.0 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5 2.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.5 3.0 GO:0010265 SCF complex assembly(GO:0010265)
0.5 4.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.5 5.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.5 2.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.5 9.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.5 1.5 GO:0042938 dipeptide transport(GO:0042938)
0.5 1.0 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.5 2.3 GO:0044336 embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.5 2.8 GO:0016926 protein desumoylation(GO:0016926)
0.5 18.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.5 3.7 GO:0010571 double-strand break repair via break-induced replication(GO:0000727) positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.5 2.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.5 7.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.5 4.5 GO:0051382 kinetochore assembly(GO:0051382)
0.5 1.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 7.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 2.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.4 1.8 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.4 0.9 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.4 2.1 GO:1903751 negative regulation of establishment of protein localization to mitochondrion(GO:1903748) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.4 2.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.4 2.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.6 GO:0031291 Ran protein signal transduction(GO:0031291)
0.4 7.4 GO:0051014 actin filament severing(GO:0051014)
0.4 2.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 2.0 GO:0007386 compartment pattern specification(GO:0007386)
0.4 0.8 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 1.6 GO:1904796 regulation of core promoter binding(GO:1904796)
0.4 1.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 6.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.4 5.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.4 2.6 GO:0035898 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.4 1.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 1.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 1.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.4 6.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 3.9 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.4 1.1 GO:0050894 determination of affect(GO:0050894)
0.4 2.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.4 7.4 GO:0035855 megakaryocyte development(GO:0035855)
0.4 2.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 5.7 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.3 7.9 GO:0036010 protein localization to endosome(GO:0036010)
0.3 1.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 2.3 GO:0002858 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.3 4.8 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 2.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.3 4.5 GO:0045116 protein neddylation(GO:0045116)
0.3 6.6 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.3 0.6 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.3 4.2 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.3 2.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.3 2.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.3 2.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 3.6 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.3 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 2.9 GO:0051601 exocyst localization(GO:0051601)
0.3 1.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 3.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.3 2.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.3 1.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 6.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 5.0 GO:0016180 snRNA processing(GO:0016180)
0.2 1.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 5.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 0.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.2 4.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.2 6.2 GO:0016578 histone deubiquitination(GO:0016578)
0.2 8.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 20.0 GO:0016575 histone deacetylation(GO:0016575)
0.2 4.6 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.2 3.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.2 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.2 0.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 0.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 1.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 5.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 3.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.8 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 6.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.7 GO:1901838 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2 4.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 3.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 5.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.2 1.9 GO:0045820 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.2 1.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.2 0.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 14.3 GO:0006968 cellular defense response(GO:0006968)
0.2 0.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 1.3 GO:0070459 prolactin secretion(GO:0070459)
0.2 8.8 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.2 1.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 2.2 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.1 6.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 4.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 3.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.4 GO:0048850 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1 1.3 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 9.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 2.8 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.9 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.5 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.1 4.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 2.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 3.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 4.2 GO:0043029 T cell homeostasis(GO:0043029)
0.1 3.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 7.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 13.9 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.1 3.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.7 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.9 GO:0097012 serotonin metabolic process(GO:0042428) cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 1.2 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 1.7 GO:0044804 nucleophagy(GO:0044804)
0.1 3.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 28.8 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 5.2 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 3.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 6.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 1.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.8 GO:0071468 cellular response to acidic pH(GO:0071468)
0.1 14.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 3.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 4.4 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 6.7 GO:0031100 organ regeneration(GO:0031100)
0.1 7.0 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 8.9 GO:0009267 cellular response to starvation(GO:0009267)
0.1 1.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 2.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.7 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.1 3.9 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.1 0.2 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.6 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 2.0 GO:0010470 regulation of gastrulation(GO:0010470)
0.1 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 5.7 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.9 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 3.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 2.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.7 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 4.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 3.1 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 1.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.7 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.7 GO:0007566 embryo implantation(GO:0007566)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.0 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.1 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
4.2 50.1 GO:0005642 annulate lamellae(GO:0005642)
3.9 7.9 GO:0031010 ISWI-type complex(GO:0031010)
3.6 25.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
2.5 17.5 GO:0097452 GAIT complex(GO:0097452)
2.4 19.6 GO:0035976 AP1 complex(GO:0035976)
1.8 37.3 GO:0000812 Swr1 complex(GO:0000812)
1.7 12.0 GO:0072487 MSL complex(GO:0072487)
1.6 25.2 GO:0097346 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
1.5 9.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.5 7.5 GO:0036398 TCR signalosome(GO:0036398)
1.5 7.4 GO:0044530 supraspliceosomal complex(GO:0044530)
1.4 2.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.2 17.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
1.2 9.8 GO:0032010 phagolysosome(GO:0032010)
1.2 4.9 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.2 16.3 GO:0042405 nuclear inclusion body(GO:0042405)
1.0 4.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.0 5.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.9 6.6 GO:0071203 WASH complex(GO:0071203)
0.9 11.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.9 4.3 GO:0097422 tubular endosome(GO:0097422)
0.8 2.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.8 18.2 GO:0071564 npBAF complex(GO:0071564)
0.8 6.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.7 5.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 4.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.7 5.5 GO:0042382 paraspeckles(GO:0042382)
0.7 17.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.7 7.9 GO:0090543 Flemming body(GO:0090543)
0.6 5.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.6 5.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.6 3.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.6 3.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.6 33.4 GO:1990391 DNA repair complex(GO:1990391)
0.6 5.1 GO:0034709 methylosome(GO:0034709)
0.6 5.0 GO:0032039 integrator complex(GO:0032039)
0.5 6.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 4.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 14.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 1.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 1.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.4 3.1 GO:0031415 NatA complex(GO:0031415)
0.4 47.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.4 4.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.4 44.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.4 1.9 GO:0071986 Ragulator complex(GO:0071986)
0.4 1.5 GO:0000798 nuclear cohesin complex(GO:0000798)
0.4 12.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 2.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 1.7 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.3 1.6 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.3 3.7 GO:0044327 dendritic spine head(GO:0044327)
0.3 34.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 0.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 7.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 4.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 6.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 4.3 GO:0032059 bleb(GO:0032059)
0.2 4.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 3.5 GO:0000124 SAGA complex(GO:0000124)
0.2 1.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 7.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 43.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 5.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 6.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 6.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 3.0 GO:0031519 PcG protein complex(GO:0031519)
0.2 0.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 3.9 GO:0030056 hemidesmosome(GO:0030056)
0.2 4.6 GO:0035861 site of double-strand break(GO:0035861)
0.2 2.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 5.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.1 GO:0097433 dense body(GO:0097433)
0.2 8.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 3.6 GO:0031527 filopodium membrane(GO:0031527)
0.2 0.8 GO:0044308 axonal spine(GO:0044308)
0.1 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.6 GO:0033391 chromatoid body(GO:0033391)
0.1 1.0 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 17.0 GO:0000922 spindle pole(GO:0000922)
0.1 8.6 GO:0005811 lipid particle(GO:0005811)
0.1 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 14.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 12.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 12.2 GO:0016605 PML body(GO:0016605)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 2.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 3.3 GO:1904115 axon cytoplasm(GO:1904115)
0.1 8.5 GO:0005681 spliceosomal complex(GO:0005681)
0.1 2.5 GO:0030686 90S preribosome(GO:0030686)
0.1 23.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 2.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 2.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 1.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 3.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 8.0 GO:0031985 Golgi cisterna(GO:0031985)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 7.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 17.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 2.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 5.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0030018 Z disc(GO:0030018)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) apical junction complex(GO:0043296)
0.0 7.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 3.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.0 GO:0000785 chromatin(GO:0000785)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
17.4 52.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
3.9 15.7 GO:0004132 dCMP deaminase activity(GO:0004132)
2.9 29.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.5 7.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
2.4 12.1 GO:0008420 CTD phosphatase activity(GO:0008420)
2.3 13.8 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
2.2 23.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.2 6.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.8 7.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.8 14.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.7 25.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.7 5.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.6 6.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.6 17.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.5 7.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.4 4.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
1.4 12.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3 51.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
1.3 23.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.2 21.9 GO:0019992 diacylglycerol binding(GO:0019992)
1.1 9.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.1 6.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.1 15.1 GO:0050786 RAGE receptor binding(GO:0050786)
1.1 9.6 GO:1990226 histone methyltransferase binding(GO:1990226)
1.0 18.0 GO:0005522 profilin binding(GO:0005522)
1.0 9.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.0 13.6 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.9 16.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.9 8.6 GO:0051425 PTB domain binding(GO:0051425)
0.8 2.5 GO:0004766 spermidine synthase activity(GO:0004766)
0.8 44.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.8 7.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.8 8.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.8 6.5 GO:0030957 Tat protein binding(GO:0030957)
0.8 6.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.8 2.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.8 10.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.8 3.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.7 3.7 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224)
0.7 8.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 4.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 10.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.7 2.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.7 3.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.6 5.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 1.9 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.6 17.5 GO:0008143 poly(A) binding(GO:0008143)
0.6 2.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.6 4.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.6 2.4 GO:0036033 mediator complex binding(GO:0036033)
0.6 6.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.6 16.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6 33.8 GO:0004407 histone deacetylase activity(GO:0004407)
0.6 11.8 GO:0051400 BH domain binding(GO:0051400)
0.6 10.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.6 6.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 5.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.6 1.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.6 14.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 6.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 28.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 7.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 4.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein antigen binding(GO:1990405)
0.5 3.5 GO:0050733 RS domain binding(GO:0050733)
0.5 28.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.4 1.8 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.4 3.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.4 2.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.4 3.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 7.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 2.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 22.2 GO:0070888 E-box binding(GO:0070888)
0.4 17.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 2.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 1.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 1.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 6.0 GO:0031996 thioesterase binding(GO:0031996)
0.4 2.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 3.6 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 46.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 1.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.3 2.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.3 5.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 1.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 1.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.3 6.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 5.6 GO:0004697 protein kinase C activity(GO:0004697)
0.3 2.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 2.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 0.6 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.3 6.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 10.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 4.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 0.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 2.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 3.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 13.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 1.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 3.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 2.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.7 GO:0001515 opioid peptide activity(GO:0001515)
0.2 4.5 GO:0097602 cullin family protein binding(GO:0097602)
0.2 2.4 GO:0045545 syndecan binding(GO:0045545)
0.2 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 1.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 5.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 0.8 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 2.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 10.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 9.8 GO:0035064 methylated histone binding(GO:0035064)
0.2 1.6 GO:0034452 dynactin binding(GO:0034452)
0.2 9.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 5.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 8.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 3.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 5.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 9.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 6.1 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 6.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.6 GO:0039552 RIG-I binding(GO:0039552)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 6.2 GO:0019843 rRNA binding(GO:0019843)
0.1 5.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 4.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 4.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 3.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 4.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.1 GO:0005501 retinoic acid binding(GO:0001972) retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.1 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.1 2.7 GO:0042287 MHC protein binding(GO:0042287)
0.1 2.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.4 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 4.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 7.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 9.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.3 GO:0046332 SMAD binding(GO:0046332)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 9.8 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.6 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 25.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.7 51.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
1.4 35.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.0 19.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.9 28.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 6.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.5 36.2 PID P53 REGULATION PATHWAY p53 pathway
0.5 13.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5 14.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.5 32.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.5 55.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.5 9.2 PID IL5 PATHWAY IL5-mediated signaling events
0.5 17.3 PID MYC PATHWAY C-MYC pathway
0.3 5.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 22.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 3.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 6.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.3 13.3 PID CDC42 PATHWAY CDC42 signaling events
0.3 16.3 PID PLK1 PATHWAY PLK1 signaling events
0.2 2.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 5.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 11.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 4.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 3.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 16.1 PID E2F PATHWAY E2F transcription factor network
0.2 19.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 11.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 7.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 5.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 5.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 7.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 15.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 5.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 3.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 6.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 3.8 PID INSULIN PATHWAY Insulin Pathway
0.1 4.6 PID ATM PATHWAY ATM pathway
0.1 4.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 5.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 7.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 55.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.1 5.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.1 22.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.0 17.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.9 25.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8 15.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.7 17.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 12.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.5 24.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.5 15.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 17.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 7.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.4 2.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.4 15.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 17.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 21.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 7.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 4.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.3 9.3 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3 8.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3 7.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 6.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 24.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 44.4 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.3 6.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 7.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 7.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.3 4.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 4.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.2 2.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 8.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 38.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 5.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 1.8 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 10.2 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.2 8.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 5.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 6.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 11.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 4.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 2.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 1.8 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.1 2.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 6.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 5.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 2.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 8.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 4.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.4 REACTOME TRANSLATION Genes involved in Translation
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 5.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion