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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for NFKB2
Z-value: 0.08
Motif logo
Transcription factors associated with NFKB2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NFKB2
|
ENSG00000077150.13 | nuclear factor kappa B subunit 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFKB2 | hg19_v2_chr10_+_104155450_104155479 | 0.53 | 7.4e-17 | Click! |
Activity profile of NFKB2 motif
Sorted Z-values of NFKB2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_37640277 | 28.30 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr1_-_27961720 | 24.30 |
ENST00000545953.1
ENST00000374005.3 |
FGR
|
feline Gardner-Rasheed sarcoma viral oncogene homolog |
| chr6_+_32605195 | 21.69 |
ENST00000374949.2
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr14_+_24605389 | 20.54 |
ENST00000382708.3
ENST00000561435.1 |
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| chr22_-_37640456 | 19.73 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr14_-_24615805 | 17.47 |
ENST00000560410.1
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr19_-_41859814 | 17.45 |
ENST00000221930.5
|
TGFB1
|
transforming growth factor, beta 1 |
| chr19_-_10450328 | 17.39 |
ENST00000160262.5
|
ICAM3
|
intercellular adhesion molecule 3 |
| chr14_+_24605361 | 16.46 |
ENST00000206451.6
ENST00000559123.1 |
PSME1
|
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| chr19_+_48824711 | 16.29 |
ENST00000599704.1
|
EMP3
|
epithelial membrane protein 3 |
| chr17_-_34207295 | 15.96 |
ENST00000463941.1
ENST00000293272.3 |
CCL5
|
chemokine (C-C motif) ligand 5 |
| chr6_-_31324943 | 15.68 |
ENST00000412585.2
ENST00000434333.1 |
HLA-B
|
major histocompatibility complex, class I, B |
| chr11_+_34460447 | 15.09 |
ENST00000241052.4
|
CAT
|
catalase |
| chr6_+_32605134 | 15.02 |
ENST00000343139.5
ENST00000395363.1 ENST00000496318.1 |
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr2_-_89292422 | 13.50 |
ENST00000495489.1
|
IGKV1-8
|
immunoglobulin kappa variable 1-8 |
| chr14_-_24616426 | 13.13 |
ENST00000216802.5
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr2_-_89417335 | 12.88 |
ENST00000490686.1
|
IGKV1-17
|
immunoglobulin kappa variable 1-17 |
| chrX_+_64887512 | 12.67 |
ENST00000360270.5
|
MSN
|
moesin |
| chr17_+_76164639 | 12.36 |
ENST00000225777.3
ENST00000585591.1 ENST00000589711.1 ENST00000588282.1 ENST00000589168.1 |
SYNGR2
|
synaptogyrin 2 |
| chr11_+_66247880 | 11.97 |
ENST00000360510.2
ENST00000453114.1 ENST00000541961.1 ENST00000532019.1 ENST00000526515.1 ENST00000530165.1 ENST00000533725.1 |
DPP3
|
dipeptidyl-peptidase 3 |
| chr17_+_76165213 | 11.96 |
ENST00000590201.1
|
SYNGR2
|
synaptogyrin 2 |
| chr5_-_150466692 | 11.90 |
ENST00000315050.7
ENST00000523338.1 ENST00000522100.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr19_+_42381173 | 11.79 |
ENST00000221972.3
|
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr1_-_183559693 | 11.09 |
ENST00000367535.3
ENST00000413720.1 ENST00000418089.1 |
NCF2
|
neutrophil cytosolic factor 2 |
| chr6_+_106959718 | 10.74 |
ENST00000369066.3
|
AIM1
|
absent in melanoma 1 |
| chr12_+_7055631 | 10.69 |
ENST00000543115.1
ENST00000399448.1 |
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr16_+_50776021 | 10.48 |
ENST00000566679.2
ENST00000564634.1 ENST00000398568.2 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr17_+_16318909 | 10.46 |
ENST00000577397.1
|
TRPV2
|
transient receptor potential cation channel, subfamily V, member 2 |
| chr19_-_6415695 | 10.40 |
ENST00000594496.1
ENST00000594745.1 ENST00000600480.1 |
KHSRP
|
KH-type splicing regulatory protein |
| chr11_-_104840093 | 10.36 |
ENST00000417440.2
ENST00000444739.2 |
CASP4
|
caspase 4, apoptosis-related cysteine peptidase |
| chrX_+_49028265 | 10.35 |
ENST00000376322.3
ENST00000376327.5 |
PLP2
|
proteolipid protein 2 (colonic epithelium-enriched) |
| chr11_-_57335750 | 10.30 |
ENST00000340573.4
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6 |
| chr10_+_89622870 | 10.25 |
ENST00000371953.3
|
PTEN
|
phosphatase and tensin homolog |
| chr1_-_183560011 | 10.13 |
ENST00000367536.1
|
NCF2
|
neutrophil cytosolic factor 2 |
| chr2_-_89340242 | 10.00 |
ENST00000480492.1
|
IGKV1-12
|
immunoglobulin kappa variable 1-12 |
| chr17_+_72462525 | 9.94 |
ENST00000360141.3
|
CD300A
|
CD300a molecule |
| chr17_+_16318850 | 9.88 |
ENST00000338560.7
|
TRPV2
|
transient receptor potential cation channel, subfamily V, member 2 |
| chr1_-_183604794 | 9.82 |
ENST00000367534.1
ENST00000359856.6 ENST00000294742.6 |
ARPC5
|
actin related protein 2/3 complex, subunit 5, 16kDa |
| chr9_+_100745615 | 9.57 |
ENST00000339399.4
|
ANP32B
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
| chr16_-_88878305 | 9.51 |
ENST00000569616.1
ENST00000563655.1 ENST00000567713.1 ENST00000426324.2 ENST00000378364.3 |
APRT
|
adenine phosphoribosyltransferase |
| chr12_-_76477707 | 9.32 |
ENST00000551992.1
|
NAP1L1
|
nucleosome assembly protein 1-like 1 |
| chr16_+_81812863 | 9.20 |
ENST00000359376.3
|
PLCG2
|
phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| chr2_-_89310012 | 9.10 |
ENST00000493819.1
|
IGKV1-9
|
immunoglobulin kappa variable 1-9 |
| chr20_-_4795747 | 8.88 |
ENST00000379376.2
|
RASSF2
|
Ras association (RalGDS/AF-6) domain family member 2 |
| chr12_+_56110374 | 8.64 |
ENST00000549424.1
|
RP11-644F5.10
|
Uncharacterized protein |
| chr11_+_66247478 | 8.63 |
ENST00000531863.1
ENST00000532677.1 |
DPP3
|
dipeptidyl-peptidase 3 |
| chr19_+_42381337 | 8.58 |
ENST00000597454.1
ENST00000444740.2 |
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr3_-_182698381 | 8.56 |
ENST00000292782.4
|
DCUN1D1
|
DCN1, defective in cullin neddylation 1, domain containing 1 |
| chr17_+_72462766 | 8.37 |
ENST00000392625.3
ENST00000361933.3 ENST00000310828.5 |
CD300A
|
CD300a molecule |
| chr10_-_125851961 | 8.26 |
ENST00000346248.5
|
CHST15
|
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| chr17_+_40440481 | 8.06 |
ENST00000590726.2
ENST00000452307.2 ENST00000444283.1 ENST00000588868.1 |
STAT5A
|
signal transducer and activator of transcription 5A |
| chr3_+_53195136 | 8.02 |
ENST00000394729.2
ENST00000330452.3 |
PRKCD
|
protein kinase C, delta |
| chr1_+_42922173 | 7.82 |
ENST00000455780.1
ENST00000372560.3 ENST00000372561.3 ENST00000372556.3 |
PPCS
|
phosphopantothenoylcysteine synthetase |
| chr11_+_58910201 | 7.78 |
ENST00000528737.1
|
FAM111A
|
family with sequence similarity 111, member A |
| chr19_-_39330818 | 7.69 |
ENST00000594769.1
ENST00000602021.1 |
AC104534.3
|
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial |
| chr1_+_207494853 | 7.52 |
ENST00000367064.3
ENST00000367063.2 ENST00000391921.4 ENST00000367067.4 ENST00000314754.8 ENST00000367065.5 ENST00000391920.4 ENST00000367062.4 ENST00000343420.6 |
CD55
|
CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| chr16_+_4674814 | 7.40 |
ENST00000415496.1
ENST00000587747.1 ENST00000399577.5 ENST00000588994.1 ENST00000586183.1 |
MGRN1
|
mahogunin ring finger 1, E3 ubiquitin protein ligase |
| chr1_-_40042416 | 7.30 |
ENST00000372857.3
ENST00000372856.3 ENST00000531243.2 ENST00000451091.2 |
PABPC4
|
poly(A) binding protein, cytoplasmic 4 (inducible form) |
| chr1_+_42921761 | 7.27 |
ENST00000372562.1
|
PPCS
|
phosphopantothenoylcysteine synthetase |
| chr2_-_89568263 | 7.24 |
ENST00000473726.1
|
IGKV1-33
|
immunoglobulin kappa variable 1-33 |
| chr8_+_90770008 | 7.20 |
ENST00000540020.1
|
RIPK2
|
receptor-interacting serine-threonine kinase 2 |
| chr22_+_35796108 | 7.14 |
ENST00000382011.5
ENST00000416905.1 |
MCM5
|
minichromosome maintenance complex component 5 |
| chr2_+_219081817 | 7.05 |
ENST00000315717.5
ENST00000420104.1 ENST00000295685.10 |
ARPC2
|
actin related protein 2/3 complex, subunit 2, 34kDa |
| chr2_+_89952792 | 6.99 |
ENST00000390265.2
|
IGKV1D-33
|
immunoglobulin kappa variable 1D-33 |
| chr11_+_65405556 | 6.94 |
ENST00000534313.1
ENST00000533361.1 ENST00000526137.1 |
SIPA1
|
signal-induced proliferation-associated 1 |
| chr10_-_36813162 | 6.92 |
ENST00000440465.1
|
NAMPTL
|
nicotinamide phosphoribosyltransferase-like |
| chr1_-_33283754 | 6.86 |
ENST00000373477.4
|
YARS
|
tyrosyl-tRNA synthetase |
| chr3_+_23847432 | 6.59 |
ENST00000346855.3
|
UBE2E1
|
ubiquitin-conjugating enzyme E2E 1 |
| chr22_+_35796056 | 6.56 |
ENST00000216122.4
|
MCM5
|
minichromosome maintenance complex component 5 |
| chr1_+_226250379 | 6.49 |
ENST00000366815.3
ENST00000366814.3 |
H3F3A
|
H3 histone, family 3A |
| chr12_+_56110247 | 6.45 |
ENST00000551926.1
|
BLOC1S1
|
biogenesis of lysosomal organelles complex-1, subunit 1 |
| chr2_-_89247338 | 6.45 |
ENST00000496168.1
|
IGKV1-5
|
immunoglobulin kappa variable 1-5 |
| chrX_-_118986911 | 6.35 |
ENST00000276201.2
ENST00000345865.2 |
UPF3B
|
UPF3 regulator of nonsense transcripts homolog B (yeast) |
| chr11_+_64949158 | 6.31 |
ENST00000527739.1
ENST00000526966.1 ENST00000533129.1 ENST00000524773.1 |
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr6_-_32157947 | 6.22 |
ENST00000375050.4
|
PBX2
|
pre-B-cell leukemia homeobox 2 |
| chr1_-_150207017 | 6.16 |
ENST00000369119.3
|
ANP32E
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| chr16_-_15736881 | 6.12 |
ENST00000540441.2
|
KIAA0430
|
KIAA0430 |
| chr1_+_2487800 | 6.03 |
ENST00000355716.4
|
TNFRSF14
|
tumor necrosis factor receptor superfamily, member 14 |
| chr16_-_28222797 | 5.98 |
ENST00000569951.1
ENST00000565698.1 |
XPO6
|
exportin 6 |
| chr3_+_23847394 | 5.98 |
ENST00000306627.3
|
UBE2E1
|
ubiquitin-conjugating enzyme E2E 1 |
| chr11_+_64949899 | 5.92 |
ENST00000531068.1
ENST00000527699.1 ENST00000533909.1 ENST00000527323.1 |
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr16_-_15736953 | 5.88 |
ENST00000548025.1
ENST00000551742.1 ENST00000602337.1 ENST00000344181.3 ENST00000396368.3 |
KIAA0430
|
KIAA0430 |
| chr1_-_89458287 | 5.62 |
ENST00000370485.2
|
CCBL2
|
cysteine conjugate-beta lyase 2 |
| chr8_+_22446763 | 5.61 |
ENST00000450780.2
ENST00000430850.2 ENST00000447849.1 |
AC037459.4
|
Uncharacterized protein |
| chr10_+_104154229 | 5.53 |
ENST00000428099.1
ENST00000369966.3 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr8_+_22436248 | 5.49 |
ENST00000308354.7
|
PDLIM2
|
PDZ and LIM domain 2 (mystique) |
| chr1_-_205744574 | 5.47 |
ENST00000367139.3
ENST00000235932.4 ENST00000437324.2 ENST00000414729.1 |
RAB7L1
|
RAB7, member RAS oncogene family-like 1 |
| chr8_+_22436635 | 5.36 |
ENST00000452226.1
ENST00000397760.4 ENST00000339162.7 ENST00000397761.2 |
PDLIM2
|
PDZ and LIM domain 2 (mystique) |
| chr11_+_64949343 | 5.35 |
ENST00000279247.6
ENST00000532285.1 ENST00000534373.1 |
CAPN1
|
calpain 1, (mu/I) large subunit |
| chr12_+_69080734 | 5.28 |
ENST00000378905.2
|
NUP107
|
nucleoporin 107kDa |
| chr6_+_135502408 | 5.28 |
ENST00000341911.5
ENST00000442647.2 ENST00000316528.8 |
MYB
|
v-myb avian myeloblastosis viral oncogene homolog |
| chr1_+_231376941 | 5.27 |
ENST00000436239.1
ENST00000366647.4 ENST00000366646.3 ENST00000416000.1 |
GNPAT
|
glyceronephosphate O-acyltransferase |
| chr14_+_97263641 | 5.26 |
ENST00000216639.3
|
VRK1
|
vaccinia related kinase 1 |
| chr11_+_58910295 | 5.21 |
ENST00000420244.1
|
FAM111A
|
family with sequence similarity 111, member A |
| chr19_-_1885432 | 5.17 |
ENST00000250974.9
|
ABHD17A
|
abhydrolase domain containing 17A |
| chr11_+_66406088 | 5.11 |
ENST00000310092.7
ENST00000396053.4 ENST00000408993.2 |
RBM4
|
RNA binding motif protein 4 |
| chr8_+_145582231 | 5.10 |
ENST00000526338.1
ENST00000402965.1 ENST00000534725.1 ENST00000532887.1 ENST00000329994.2 |
SLC52A2
|
solute carrier family 52 (riboflavin transporter), member 2 |
| chr16_-_28223166 | 5.00 |
ENST00000304658.5
|
XPO6
|
exportin 6 |
| chr1_-_89458415 | 4.98 |
ENST00000321792.5
ENST00000370491.3 |
RBMXL1
CCBL2
|
RNA binding motif protein, X-linked-like 1 cysteine conjugate-beta lyase 2 |
| chr17_+_34900737 | 4.97 |
ENST00000304718.4
ENST00000485685.2 |
GGNBP2
|
gametogenetin binding protein 2 |
| chr9_+_134103496 | 4.96 |
ENST00000498010.1
ENST00000476004.1 ENST00000528406.1 |
NUP214
|
nucleoporin 214kDa |
| chr1_-_155232047 | 4.86 |
ENST00000302631.3
|
SCAMP3
|
secretory carrier membrane protein 3 |
| chr17_-_5487277 | 4.81 |
ENST00000572272.1
ENST00000354411.3 ENST00000577119.1 |
NLRP1
|
NLR family, pyrin domain containing 1 |
| chr10_+_22605374 | 4.71 |
ENST00000448361.1
|
COMMD3
|
COMM domain containing 3 |
| chr20_-_48330377 | 4.70 |
ENST00000371711.4
|
B4GALT5
|
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| chr2_-_197036289 | 4.68 |
ENST00000263955.4
|
STK17B
|
serine/threonine kinase 17b |
| chr14_-_24615523 | 4.67 |
ENST00000559056.1
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr12_+_12870055 | 4.63 |
ENST00000228872.4
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| chr1_-_146082633 | 4.61 |
ENST00000605317.1
ENST00000604938.1 ENST00000339388.5 |
NBPF11
|
neuroblastoma breakpoint family, member 11 |
| chr1_-_28559502 | 4.61 |
ENST00000263697.4
|
DNAJC8
|
DnaJ (Hsp40) homolog, subfamily C, member 8 |
| chr16_-_4465886 | 4.59 |
ENST00000539968.1
|
CORO7
|
coronin 7 |
| chr7_+_73588575 | 4.55 |
ENST00000265753.8
|
EIF4H
|
eukaryotic translation initiation factor 4H |
| chr11_+_6624955 | 4.54 |
ENST00000299421.4
ENST00000537806.1 |
ILK
|
integrin-linked kinase |
| chr6_-_17706618 | 4.53 |
ENST00000262077.2
ENST00000537253.1 |
NUP153
|
nucleoporin 153kDa |
| chr4_-_860950 | 4.53 |
ENST00000511980.1
ENST00000510799.1 |
GAK
|
cyclin G associated kinase |
| chr1_-_47655686 | 4.51 |
ENST00000294338.2
|
PDZK1IP1
|
PDZK1 interacting protein 1 |
| chr17_+_7462103 | 4.43 |
ENST00000396545.4
|
TNFSF13
|
tumor necrosis factor (ligand) superfamily, member 13 |
| chr12_+_56109926 | 4.38 |
ENST00000547076.1
|
BLOC1S1
|
biogenesis of lysosomal organelles complex-1, subunit 1 |
| chr11_-_3862206 | 4.36 |
ENST00000351018.4
|
RHOG
|
ras homolog family member G |
| chr19_-_14628645 | 4.36 |
ENST00000598235.1
|
DNAJB1
|
DnaJ (Hsp40) homolog, subfamily B, member 1 |
| chr19_-_1885511 | 4.36 |
ENST00000292577.7
|
ABHD17A
|
abhydrolase domain containing 17A |
| chr11_+_6625046 | 4.31 |
ENST00000396751.2
|
ILK
|
integrin-linked kinase |
| chr8_+_145582217 | 4.11 |
ENST00000530047.1
ENST00000527078.1 |
SLC52A2
|
solute carrier family 52 (riboflavin transporter), member 2 |
| chr14_-_23058063 | 4.09 |
ENST00000538631.1
ENST00000543337.1 ENST00000250498.4 |
DAD1
|
defender against cell death 1 |
| chr16_+_15737124 | 4.02 |
ENST00000396355.1
ENST00000396353.2 |
NDE1
|
nudE neurodevelopment protein 1 |
| chr22_-_43411106 | 3.97 |
ENST00000453643.1
ENST00000263246.3 ENST00000337959.4 |
PACSIN2
|
protein kinase C and casein kinase substrate in neurons 2 |
| chr1_-_202129105 | 3.97 |
ENST00000367279.4
|
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr16_-_67281413 | 3.95 |
ENST00000258201.4
|
FHOD1
|
formin homology 2 domain containing 1 |
| chrX_-_23761317 | 3.94 |
ENST00000492081.1
ENST00000379303.5 ENST00000336430.7 |
ACOT9
|
acyl-CoA thioesterase 9 |
| chr2_-_16847084 | 3.88 |
ENST00000406434.1
ENST00000381323.3 |
FAM49A
|
family with sequence similarity 49, member A |
| chr17_-_3819751 | 3.86 |
ENST00000225538.3
|
P2RX1
|
purinergic receptor P2X, ligand-gated ion channel, 1 |
| chr14_+_100705322 | 3.86 |
ENST00000262238.4
|
YY1
|
YY1 transcription factor |
| chr17_+_38497640 | 3.85 |
ENST00000394086.3
|
RARA
|
retinoic acid receptor, alpha |
| chr20_+_35807512 | 3.82 |
ENST00000373622.5
|
RPN2
|
ribophorin II |
| chr15_+_85923797 | 3.80 |
ENST00000559362.1
|
AKAP13
|
A kinase (PRKA) anchor protein 13 |
| chr8_+_86376081 | 3.78 |
ENST00000285379.5
|
CA2
|
carbonic anhydrase II |
| chr8_-_130951940 | 3.75 |
ENST00000522250.1
ENST00000522941.1 ENST00000522746.1 ENST00000520204.1 ENST00000519070.1 ENST00000520254.1 ENST00000519824.2 ENST00000519540.1 |
FAM49B
|
family with sequence similarity 49, member B |
| chr11_-_61560053 | 3.74 |
ENST00000537328.1
|
TMEM258
|
transmembrane protein 258 |
| chr1_+_90287480 | 3.73 |
ENST00000394593.3
|
LRRC8D
|
leucine rich repeat containing 8 family, member D |
| chr11_-_33891362 | 3.70 |
ENST00000395833.3
|
LMO2
|
LIM domain only 2 (rhombotin-like 1) |
| chr2_+_61108650 | 3.68 |
ENST00000295025.8
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr15_+_77287426 | 3.68 |
ENST00000558012.1
ENST00000267939.5 ENST00000379595.3 |
PSTPIP1
|
proline-serine-threonine phosphatase interacting protein 1 |
| chr5_+_73980965 | 3.61 |
ENST00000261416.7
|
HEXB
|
hexosaminidase B (beta polypeptide) |
| chr6_+_14117872 | 3.61 |
ENST00000379153.3
|
CD83
|
CD83 molecule |
| chr10_+_22605304 | 3.59 |
ENST00000475460.2
ENST00000602390.1 ENST00000489125.2 ENST00000456711.1 ENST00000444869.1 |
COMMD3-BMI1
COMMD3
|
COMMD3-BMI1 readthrough COMM domain containing 3 |
| chr12_+_56110315 | 3.57 |
ENST00000548556.1
|
BLOC1S1
|
biogenesis of lysosomal organelles complex-1, subunit 1 |
| chr8_-_145641864 | 3.50 |
ENST00000276833.5
|
SLC39A4
|
solute carrier family 39 (zinc transporter), member 4 |
| chr1_+_52195480 | 3.48 |
ENST00000531828.1
ENST00000361556.5 ENST00000481937.1 |
OSBPL9
|
oxysterol binding protein-like 9 |
| chr11_+_706113 | 3.46 |
ENST00000318562.8
ENST00000533256.1 ENST00000534755.1 |
EPS8L2
|
EPS8-like 2 |
| chr16_-_4466622 | 3.43 |
ENST00000570645.1
ENST00000574025.1 ENST00000572898.1 ENST00000537233.2 ENST00000571059.1 ENST00000251166.4 |
CORO7
|
coronin 7 |
| chr3_+_107241783 | 3.40 |
ENST00000415149.2
ENST00000402543.1 ENST00000325805.8 ENST00000427402.1 |
BBX
|
bobby sox homolog (Drosophila) |
| chr16_+_50775971 | 3.40 |
ENST00000311559.9
ENST00000564326.1 ENST00000566206.1 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr2_+_74153953 | 3.40 |
ENST00000264093.4
ENST00000348222.1 |
DGUOK
|
deoxyguanosine kinase |
| chr7_+_73588665 | 3.37 |
ENST00000353999.6
|
EIF4H
|
eukaryotic translation initiation factor 4H |
| chr9_+_130922537 | 3.34 |
ENST00000372994.1
|
C9orf16
|
chromosome 9 open reading frame 16 |
| chrX_-_15872914 | 3.33 |
ENST00000380291.1
ENST00000545766.1 ENST00000421527.2 ENST00000329235.2 |
AP1S2
|
adaptor-related protein complex 1, sigma 2 subunit |
| chr19_+_22235310 | 3.33 |
ENST00000600162.1
|
ZNF257
|
zinc finger protein 257 |
| chr17_+_21191341 | 3.33 |
ENST00000526076.2
ENST00000361818.5 ENST00000316920.6 |
MAP2K3
|
mitogen-activated protein kinase kinase 3 |
| chr15_+_85923856 | 3.31 |
ENST00000560302.1
ENST00000394518.2 ENST00000361243.2 ENST00000560256.1 |
AKAP13
|
A kinase (PRKA) anchor protein 13 |
| chr2_-_197664366 | 3.31 |
ENST00000409364.3
ENST00000263956.3 |
GTF3C3
|
general transcription factor IIIC, polypeptide 3, 102kDa |
| chr9_+_130911723 | 3.29 |
ENST00000277480.2
ENST00000373013.2 ENST00000540948.1 |
LCN2
|
lipocalin 2 |
| chr2_-_219157250 | 3.28 |
ENST00000434015.2
ENST00000444183.1 ENST00000420341.1 ENST00000453281.1 ENST00000258412.3 ENST00000440422.1 |
TMBIM1
|
transmembrane BAX inhibitor motif containing 1 |
| chr2_+_61108771 | 3.28 |
ENST00000394479.3
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr20_+_61584026 | 3.28 |
ENST00000370351.4
ENST00000370349.3 |
SLC17A9
|
solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| chr17_-_56429500 | 3.25 |
ENST00000225504.3
|
SUPT4H1
|
suppressor of Ty 4 homolog 1 (S. cerevisiae) |
| chr17_-_79881408 | 3.25 |
ENST00000392366.3
|
MAFG
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| chr8_+_26149007 | 3.20 |
ENST00000380737.3
ENST00000524169.1 |
PPP2R2A
|
protein phosphatase 2, regulatory subunit B, alpha |
| chr2_+_74154032 | 3.15 |
ENST00000356837.6
|
DGUOK
|
deoxyguanosine kinase |
| chr3_+_51705222 | 3.10 |
ENST00000457573.1
ENST00000341333.5 ENST00000412249.1 ENST00000425781.1 ENST00000415259.1 ENST00000395057.1 ENST00000416589.1 |
TEX264
|
testis expressed 264 |
| chr17_-_73178599 | 3.01 |
ENST00000578238.1
|
SUMO2
|
small ubiquitin-like modifier 2 |
| chr1_+_24117627 | 3.00 |
ENST00000400061.1
|
LYPLA2
|
lysophospholipase II |
| chr3_-_56717246 | 2.99 |
ENST00000355628.5
|
FAM208A
|
family with sequence similarity 208, member A |
| chr11_-_61560254 | 2.96 |
ENST00000543510.1
|
TMEM258
|
transmembrane protein 258 |
| chr12_+_70637494 | 2.95 |
ENST00000548159.1
ENST00000549750.1 ENST00000551043.1 |
CNOT2
|
CCR4-NOT transcription complex, subunit 2 |
| chr17_+_7123125 | 2.95 |
ENST00000356839.5
ENST00000583312.1 ENST00000350303.5 |
ACADVL
|
acyl-CoA dehydrogenase, very long chain |
| chr1_-_209824643 | 2.94 |
ENST00000391911.1
ENST00000415782.1 |
LAMB3
|
laminin, beta 3 |
| chr10_+_112257596 | 2.91 |
ENST00000369583.3
|
DUSP5
|
dual specificity phosphatase 5 |
| chr17_+_60536002 | 2.89 |
ENST00000582809.1
|
TLK2
|
tousled-like kinase 2 |
| chr2_+_86947296 | 2.84 |
ENST00000283632.4
|
RMND5A
|
required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| chr9_+_130911770 | 2.83 |
ENST00000372998.1
|
LCN2
|
lipocalin 2 |
| chr1_-_154943212 | 2.80 |
ENST00000368445.5
ENST00000448116.2 ENST00000368449.4 |
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1 |
| chr12_-_57504069 | 2.79 |
ENST00000543873.2
ENST00000554663.1 ENST00000557635.1 |
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr1_-_202129704 | 2.74 |
ENST00000476061.1
ENST00000544762.1 ENST00000467283.1 ENST00000464870.1 ENST00000435759.2 ENST00000486116.1 ENST00000543735.1 ENST00000308986.5 ENST00000477625.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr19_-_45927097 | 2.74 |
ENST00000340192.7
|
ERCC1
|
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) |
| chr6_+_31540056 | 2.68 |
ENST00000418386.2
|
LTA
|
lymphotoxin alpha |
| chr18_+_21529811 | 2.66 |
ENST00000588004.1
|
LAMA3
|
laminin, alpha 3 |
| chr1_-_205744205 | 2.60 |
ENST00000446390.2
|
RAB7L1
|
RAB7, member RAS oncogene family-like 1 |
| chr8_-_145653885 | 2.60 |
ENST00000531032.1
ENST00000292510.4 ENST00000377348.2 ENST00000530790.1 ENST00000533806.1 |
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae) |
| chr19_-_19051927 | 2.57 |
ENST00000600077.1
|
HOMER3
|
homer homolog 3 (Drosophila) |
| chr9_+_115913222 | 2.56 |
ENST00000259392.3
|
SLC31A2
|
solute carrier family 31 (copper transporter), member 2 |
| chr2_+_74056066 | 2.55 |
ENST00000339566.3
ENST00000409707.1 ENST00000452725.1 ENST00000432295.2 ENST00000424659.1 ENST00000394073.1 |
STAMBP
|
STAM binding protein |
| chr11_-_62380199 | 2.54 |
ENST00000419857.1
ENST00000394773.2 |
EML3
|
echinoderm microtubule associated protein like 3 |
| chr17_-_53499310 | 2.52 |
ENST00000262065.3
|
MMD
|
monocyte to macrophage differentiation-associated |
| chr19_-_3786253 | 2.51 |
ENST00000585778.1
|
MATK
|
megakaryocyte-associated tyrosine kinase |
| chrX_-_1572629 | 2.49 |
ENST00000534940.1
|
ASMTL
|
acetylserotonin O-methyltransferase-like |
| chr14_+_96152754 | 2.49 |
ENST00000340722.7
|
TCL1B
|
T-cell leukemia/lymphoma 1B |
| chr19_-_10676666 | 2.48 |
ENST00000539027.1
ENST00000543682.1 ENST00000361821.5 ENST00000312962.6 |
KRI1
|
KRI1 homolog (S. cerevisiae) |
| chr15_+_92396920 | 2.47 |
ENST00000318445.6
|
SLCO3A1
|
solute carrier organic anion transporter family, member 3A1 |
| chr1_+_28879588 | 2.47 |
ENST00000373830.3
|
TRNAU1AP
|
tRNA selenocysteine 1 associated protein 1 |
| chr9_-_123691047 | 2.47 |
ENST00000373887.3
|
TRAF1
|
TNF receptor-associated factor 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NFKB2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.1 | 18.3 | GO:1905154 | negative regulation of eosinophil activation(GO:1902567) negative regulation of membrane invagination(GO:1905154) negative regulation of eosinophil migration(GO:2000417) |
| 5.8 | 17.4 | GO:0046730 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 5.2 | 15.7 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 4.4 | 48.0 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 4.0 | 16.0 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 4.0 | 11.9 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 3.9 | 3.9 | GO:0002351 | serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) |
| 3.3 | 16.5 | GO:0033591 | response to L-ascorbic acid(GO:0033591) |
| 3.2 | 9.5 | GO:0044209 | AMP salvage(GO:0044209) |
| 3.1 | 9.2 | GO:0002316 | follicular B cell differentiation(GO:0002316) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 2.9 | 22.9 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 2.7 | 10.7 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 2.6 | 10.3 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 2.4 | 7.1 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 2.3 | 9.2 | GO:0032218 | riboflavin transport(GO:0032218) |
| 2.1 | 12.7 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 2.1 | 8.3 | GO:0033091 | positive regulation of immature T cell proliferation(GO:0033091) |
| 2.0 | 16.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 2.0 | 8.1 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 2.0 | 8.0 | GO:0060697 | positive regulation of phospholipid catabolic process(GO:0060697) |
| 2.0 | 7.9 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 1.8 | 5.3 | GO:1904899 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 1.7 | 5.0 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 1.6 | 6.5 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 1.6 | 6.5 | GO:0060623 | regulation of chromosome condensation(GO:0060623) |
| 1.6 | 15.7 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.5 | 4.5 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 1.5 | 7.5 | GO:2000563 | positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563) |
| 1.4 | 5.7 | GO:0002266 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
| 1.4 | 6.9 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 1.3 | 5.3 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) |
| 1.3 | 24.3 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 1.3 | 3.8 | GO:0042938 | dipeptide transport(GO:0042938) |
| 1.2 | 6.1 | GO:0015688 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 1.2 | 6.0 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 1.2 | 17.6 | GO:0097264 | self proteolysis(GO:0097264) |
| 1.1 | 8.9 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 1.1 | 5.3 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 1.0 | 10.4 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 1.0 | 3.1 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
| 1.0 | 4.0 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
| 1.0 | 3.9 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.9 | 10.4 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.9 | 2.8 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.9 | 4.6 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.9 | 93.5 | GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) |
| 0.9 | 2.7 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 0.9 | 2.6 | GO:2000395 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.8 | 8.4 | GO:0021769 | orbitofrontal cortex development(GO:0021769) |
| 0.8 | 4.9 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431) |
| 0.8 | 7.1 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.8 | 2.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.7 | 12.4 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.7 | 3.6 | GO:0007619 | courtship behavior(GO:0007619) |
| 0.7 | 15.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.7 | 4.6 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.6 | 3.7 | GO:2000567 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 0.6 | 6.9 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.6 | 7.4 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.6 | 1.8 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.6 | 11.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.6 | 1.7 | GO:2001280 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.5 | 8.6 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.5 | 4.0 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.5 | 3.9 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 0.5 | 3.3 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.5 | 3.6 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.4 | 4.0 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
| 0.4 | 3.5 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.4 | 3.0 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.4 | 3.3 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.4 | 4.9 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.4 | 26.3 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.4 | 4.1 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.4 | 2.9 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.4 | 4.7 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.3 | 3.5 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.3 | 4.5 | GO:0046831 | regulation of RNA export from nucleus(GO:0046831) |
| 0.3 | 13.9 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.3 | 37.3 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.3 | 4.8 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) negative regulation of inclusion body assembly(GO:0090084) |
| 0.3 | 9.6 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.3 | 7.1 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.3 | 16.6 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.3 | 47.9 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.3 | 4.0 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.3 | 14.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.3 | 2.6 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.3 | 4.8 | GO:0032495 | response to muramyl dipeptide(GO:0032495) |
| 0.3 | 2.5 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.3 | 3.3 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.2 | 2.5 | GO:0010803 | regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) |
| 0.2 | 0.9 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.2 | 4.4 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.2 | 8.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.2 | 2.5 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.2 | 2.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 2.0 | GO:0019732 | antifungal humoral response(GO:0019732) |
| 0.2 | 6.2 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.2 | 20.4 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.2 | 1.4 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.2 | 2.9 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.2 | 3.7 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.2 | 5.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 4.8 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.2 | 3.2 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.2 | 13.0 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.2 | 2.1 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.2 | 3.1 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 0.2 | 4.7 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.2 | 1.8 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.2 | 0.8 | GO:0044782 | cilium organization(GO:0044782) |
| 0.2 | 0.5 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.2 | 1.7 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.2 | 2.1 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
| 0.2 | 0.5 | GO:0003220 | left ventricular cardiac muscle tissue morphogenesis(GO:0003220) |
| 0.2 | 0.3 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 1.7 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 0.9 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 3.7 | GO:0044070 | regulation of anion transport(GO:0044070) |
| 0.1 | 7.9 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 6.2 | GO:0043486 | histone exchange(GO:0043486) |
| 0.1 | 1.8 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 0.1 | 0.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.1 | 4.2 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 1.9 | GO:0015732 | prostaglandin transport(GO:0015732) |
| 0.1 | 0.9 | GO:0042339 | keratan sulfate metabolic process(GO:0042339) |
| 0.1 | 6.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.1 | 3.3 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 9.3 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 2.3 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.1 | 0.4 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.1 | 3.0 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.1 | 1.0 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 2.4 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.1 | 1.3 | GO:0007249 | I-kappaB kinase/NF-kappaB signaling(GO:0007249) |
| 0.1 | 3.5 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 4.7 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.1 | 0.9 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.1 | 2.4 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) |
| 0.1 | 0.4 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.1 | 2.4 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.1 | 8.8 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 1.3 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.7 | GO:1904779 | regulation of protein localization to centrosome(GO:1904779) |
| 0.1 | 1.6 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 2.4 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 2.5 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 1.9 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 1.8 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.2 | GO:0045357 | interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.0 | 3.8 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 0.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 1.5 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 1.1 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 8.9 | GO:0002250 | adaptive immune response(GO:0002250) |
| 0.0 | 8.3 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 2.5 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
| 0.0 | 0.1 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 0.0 | 0.8 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
| 0.0 | 1.4 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.0 | 0.1 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 0.7 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 0.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 2.8 | GO:0030534 | adult behavior(GO:0030534) |
| 0.0 | 1.2 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 2.5 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 0.8 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.8 | GO:0019730 | antimicrobial humoral response(GO:0019730) |
| 0.0 | 0.4 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.1 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.1 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
| 0.0 | 3.2 | GO:0007596 | blood coagulation(GO:0007596) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.0 | 72.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 2.9 | 20.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 2.9 | 20.3 | GO:0032584 | growth cone membrane(GO:0032584) |
| 2.7 | 21.2 | GO:0032010 | phagolysosome(GO:0032010) |
| 2.4 | 7.1 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 1.7 | 36.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 1.7 | 10.4 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 1.7 | 5.0 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 1.6 | 4.8 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
| 1.4 | 15.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 1.4 | 5.7 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 1.4 | 6.9 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
| 1.2 | 14.6 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 1.1 | 8.9 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 1.1 | 6.5 | GO:0001740 | Barr body(GO:0001740) |
| 1.1 | 13.7 | GO:0042555 | MCM complex(GO:0042555) |
| 1.0 | 10.7 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.9 | 2.8 | GO:0034657 | GID complex(GO:0034657) |
| 0.9 | 10.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.8 | 3.3 | GO:0032044 | DSIF complex(GO:0032044) |
| 0.8 | 14.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.7 | 4.3 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.7 | 16.4 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.7 | 5.6 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.7 | 4.9 | GO:0070522 | nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522) |
| 0.6 | 48.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.6 | 9.9 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.5 | 4.5 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.5 | 2.4 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.5 | 1.9 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.5 | 1.4 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.5 | 3.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.4 | 38.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.4 | 1.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.4 | 2.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.4 | 3.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.4 | 5.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.4 | 2.6 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.4 | 7.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.3 | 1.0 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 0.3 | 14.4 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.3 | 23.4 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.3 | 7.9 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
| 0.3 | 3.0 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.3 | 6.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.3 | 1.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.3 | 7.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.3 | 1.8 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.2 | 3.9 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 3.9 | GO:0097346 | INO80-type complex(GO:0097346) |
| 0.2 | 23.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.2 | 1.9 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.2 | 4.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 25.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.2 | 3.9 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.2 | 8.9 | GO:0043034 | costamere(GO:0043034) |
| 0.2 | 5.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 7.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 2.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 23.4 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 2.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 26.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 1.7 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.1 | 22.8 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.1 | 3.8 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.1 | 0.7 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 0.9 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 1.8 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 3.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 5.0 | GO:1990904 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
| 0.1 | 2.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 8.9 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 2.5 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 2.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.9 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.1 | 3.3 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 5.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 7.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 10.1 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 6.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 0.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 0.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.3 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 10.8 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 5.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 4.3 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 0.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 7.5 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 14.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 8.1 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 2.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 2.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 3.0 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 2.6 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 12.1 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 0.8 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.9 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 0.4 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 3.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.3 | 72.3 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 6.1 | 24.3 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 5.8 | 17.4 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 3.8 | 22.9 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 3.4 | 10.3 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 2.6 | 36.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 2.5 | 17.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 2.4 | 7.3 | GO:0017130 | poly(C) RNA binding(GO:0017130) |
| 2.4 | 9.5 | GO:0002060 | purine nucleobase binding(GO:0002060) |
| 2.4 | 7.1 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 2.3 | 9.2 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 2.3 | 16.0 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 2.1 | 21.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 2.0 | 7.9 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 1.6 | 8.0 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 1.6 | 15.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 1.4 | 18.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 1.4 | 8.3 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 1.3 | 5.3 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 1.3 | 17.9 | GO:0050700 | CARD domain binding(GO:0050700) |
| 1.1 | 3.3 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 1.1 | 6.5 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.9 | 20.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.8 | 13.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.8 | 7.9 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.7 | 2.9 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.7 | 4.9 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.7 | 2.1 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.7 | 15.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.6 | 10.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.6 | 3.7 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
| 0.6 | 4.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.6 | 3.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.6 | 9.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.6 | 22.4 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.6 | 4.6 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.5 | 15.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.5 | 3.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.5 | 3.9 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.5 | 5.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.5 | 3.8 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.5 | 3.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.5 | 8.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.4 | 1.7 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.4 | 4.7 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.4 | 16.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.4 | 1.7 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 0.4 | 6.0 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.4 | 10.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.4 | 4.1 | GO:0004568 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 0.4 | 3.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.4 | 66.1 | GO:0003823 | antigen binding(GO:0003823) |
| 0.4 | 3.9 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.3 | 4.8 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.3 | 9.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.3 | 10.4 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.3 | 0.9 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 0.3 | 1.4 | GO:0070026 | nitric oxide binding(GO:0070026) |
| 0.3 | 13.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.3 | 4.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.3 | 4.6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.3 | 1.6 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.3 | 1.8 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.3 | 2.6 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.2 | 5.1 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.2 | 11.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.2 | 1.0 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
| 0.2 | 1.4 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.2 | 1.9 | GO:0043559 | insulin binding(GO:0043559) |
| 0.2 | 1.1 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.2 | 2.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 1.1 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.2 | 0.8 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.2 | 2.3 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.2 | 1.2 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 12.8 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.2 | 2.5 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.2 | 3.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.2 | 5.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 41.8 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.2 | 8.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.2 | 8.8 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.2 | 6.7 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.2 | 29.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.2 | 3.3 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 8.4 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.2 | 6.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 4.8 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 2.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 3.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 3.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.1 | 2.3 | GO:0016502 | G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 0.4 | GO:0044388 | superoxide dismutase copper chaperone activity(GO:0016532) small protein activating enzyme binding(GO:0044388) |
| 0.1 | 21.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.5 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 4.0 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 4.5 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 0.7 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 12.9 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.1 | 1.8 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 3.0 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 1.9 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.1 | 0.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.1 | 2.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 0.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 1.6 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.1 | 1.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 1.8 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 3.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.1 | 4.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.4 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 3.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 1.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.3 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 2.9 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 3.9 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 5.7 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.4 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.0 | 2.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 1.1 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 1.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.1 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.0 | 0.1 | GO:0010851 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.0 | 0.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.5 | GO:0051117 | ATPase binding(GO:0051117) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 73.2 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.9 | 7.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.8 | 23.5 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.7 | 25.0 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.6 | 24.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.5 | 40.8 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.5 | 7.1 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.5 | 41.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.4 | 4.8 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.4 | 25.2 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.4 | 12.7 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.3 | 17.4 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.3 | 7.1 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.3 | 9.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 6.4 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.3 | 7.5 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.3 | 19.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.2 | 2.8 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.2 | 9.1 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 5.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 9.9 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.5 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.1 | 1.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 1.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 1.7 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 3.9 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 3.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 3.2 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 3.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 3.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.0 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 4.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.4 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 0.8 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 1.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.4 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 36.7 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 1.6 | 15.7 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 1.4 | 15.1 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 1.3 | 35.0 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.2 | 17.4 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 1.2 | 63.5 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 1.1 | 10.3 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 1.1 | 15.1 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 1.0 | 72.3 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.9 | 13.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.8 | 21.2 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.8 | 10.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.7 | 33.7 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.7 | 16.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.7 | 24.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.6 | 8.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.6 | 12.6 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.6 | 3.3 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.5 | 5.6 | REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE | Genes involved in p53-Dependent G1 DNA Damage Response |
| 0.4 | 27.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.4 | 2.6 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.4 | 5.5 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.3 | 12.5 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.3 | 8.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.3 | 10.8 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.3 | 8.5 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.3 | 11.1 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.3 | 8.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 7.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.3 | 9.1 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.3 | 3.8 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.2 | 5.6 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.2 | 3.6 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.2 | 10.3 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 4.7 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.2 | 15.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.2 | 5.3 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.2 | 3.3 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 0.2 | 2.8 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 6.7 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.2 | 6.4 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.2 | 1.4 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.2 | 4.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.2 | 10.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 5.1 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.2 | 2.9 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 3.0 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 2.0 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.1 | 7.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 2.9 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 1.6 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 6.5 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 2.9 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.4 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.1 | 7.9 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.1 | 2.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 2.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.4 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 3.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.0 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.1 | 8.8 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.1 | 0.8 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 1.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.2 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 0.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 1.4 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 2.4 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 4.6 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 2.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.6 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 2.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.8 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.1 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |