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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for OLIG1

Z-value: 0.64

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Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
OLIG1
ENSG00000184221.8 oligodendrocyte transcription factor 1

Activity profile of OLIG1 motif

Sorted Z-values of OLIG1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_13835147 13.60 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr19_+_18208603 13.06 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr5_-_11588907 10.02 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr3_-_18480260 9.47 ENST00000454909.2
SATB1
SATB homeobox 1
chr5_-_11589131 8.24 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr4_-_153456153 7.96 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr15_-_45670924 7.84 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_-_98241358 7.75 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chrX_-_13835461 7.61 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr1_+_220863187 7.56 ENST00000294889.5
C1orf115
chromosome 1 open reading frame 115
chr3_-_39322728 7.54 ENST00000541347.1
ENST00000412814.1
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr6_+_69942298 7.34 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr7_-_37024665 6.82 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr1_+_50569575 6.74 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr2_+_54342574 5.99 ENST00000303536.4
ENST00000394666.3
ACYP2
acylphosphatase 2, muscle type
chr4_-_174320687 5.50 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr14_-_23822080 5.44 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr12_-_16761007 5.28 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_21915368 5.25 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr1_+_244214577 4.89 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr4_+_114214125 4.87 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr3_-_33700933 4.80 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr10_-_69597915 4.71 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_33700589 4.58 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr18_-_47813940 4.39 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC1
CXXC finger protein 1
chr2_+_89986318 4.39 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr7_-_44530479 4.35 ENST00000355451.7
NUDCD3
NudC domain containing 3
chr19_-_39390350 4.29 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr2_-_166930131 4.28 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr3_-_195310802 4.14 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr14_+_24540046 3.93 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr19_+_58095501 3.82 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr10_-_69597810 3.73 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_-_52859046 3.60 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr10_+_180987 3.35 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr3_+_62304648 3.26 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr20_-_32031680 3.16 ENST00000217381.2
SNTA1
syntrophin, alpha 1
chr2_+_166428839 3.12 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr7_+_110731062 3.03 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr6_+_31553978 2.99 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr5_+_140739537 2.84 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr19_+_12035913 2.82 ENST00000591944.1
ZNF763
Uncharacterized protein; Zinc finger protein 763
chr2_+_191792376 2.76 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr6_+_31553901 2.70 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr3_-_121379739 2.68 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_-_15902449 2.68 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr4_-_120243545 2.65 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr19_-_51472222 2.60 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chr2_+_172543967 2.47 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr1_-_52831796 2.46 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chrX_+_120181457 2.43 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr2_+_172544011 2.34 ENST00000508530.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr19_-_51472823 2.33 ENST00000310157.2
KLK6
kallikrein-related peptidase 6
chr20_+_48429233 2.32 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr8_-_145701718 2.24 ENST00000377317.4
FOXH1
forkhead box H1
chr3_-_49466686 2.24 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr5_-_115872142 2.23 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_-_39368887 2.16 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr4_+_71600144 2.15 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr1_-_21377383 2.15 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr12_-_123450986 2.14 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr3_+_42897512 2.14 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr10_+_51565108 2.10 ENST00000438493.1
ENST00000452682.1
NCOA4
nuclear receptor coactivator 4
chr1_+_104293028 2.07 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr6_+_73076432 1.98 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_65405556 1.96 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1
signal-induced proliferation-associated 1
chr2_-_183106641 1.94 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr4_+_160188889 1.94 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_70418032 1.91 ENST00000425268.1
ENST00000428751.1
ENST00000417203.1
ENST00000417865.1
ENST00000428010.1
ENST00000447804.1
ENST00000264434.2
C2orf42
chromosome 2 open reading frame 42
chr19_-_1021113 1.90 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr18_-_49557 1.89 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr12_+_6898638 1.82 ENST00000011653.4
CD4
CD4 molecule
chr2_+_210444748 1.82 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr2_+_172543919 1.81 ENST00000452242.1
ENST00000340296.4
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr19_-_54876558 1.80 ENST00000391742.2
ENST00000434277.2
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr2_-_183387064 1.80 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr14_+_69865401 1.80 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr17_-_7145475 1.79 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr10_+_180405 1.78 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
ZMYND11
zinc finger, MYND-type containing 11
chr14_+_95047725 1.76 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr2_-_183387283 1.74 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_111970353 1.71 ENST00000369732.3
OVGP1
oviductal glycoprotein 1, 120kDa
chr1_+_196743943 1.69 ENST00000471440.2
ENST00000391985.3
CFHR3
complement factor H-related 3
chr5_-_171433579 1.68 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr14_+_95047744 1.67 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_-_121843985 1.64 ENST00000264808.3
ENST00000428209.2
ENST00000515109.1
ENST00000394435.2
PRDM5
PR domain containing 5
chr5_-_111312622 1.62 ENST00000395634.3
NREP
neuronal regeneration related protein
chr1_+_24969755 1.60 ENST00000447431.2
ENST00000374389.4
SRRM1
serine/arginine repetitive matrix 1
chr17_+_11924129 1.59 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr2_-_152830441 1.59 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_44972476 1.57 ENST00000527685.1
ENST00000308212.5
TP53I11
tumor protein p53 inducible protein 11
chr4_+_154622652 1.56 ENST00000260010.6
TLR2
toll-like receptor 2
chr10_+_26727125 1.54 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr15_+_85144217 1.54 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr3_-_48936272 1.53 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr1_-_21377447 1.49 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_130737223 1.49 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr14_+_21249200 1.49 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr7_-_55930443 1.49 ENST00000388975.3
SEPT14
septin 14
chr13_+_49551020 1.47 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr6_+_17110726 1.39 ENST00000354384.5
STMND1
stathmin domain containing 1
chr9_-_132404374 1.39 ENST00000277459.4
ENST00000450050.2
ENST00000277458.4
ASB6
ankyrin repeat and SOCS box containing 6
chr21_+_42792442 1.39 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr4_+_154178520 1.38 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr1_-_146054494 1.35 ENST00000401009.2
NBPF11
neuroblastoma breakpoint family, member 11
chr2_-_175462934 1.35 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr1_+_159272111 1.34 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr8_+_48173514 1.32 ENST00000518074.1
ENST00000541342.1
SPIDR
scaffolding protein involved in DNA repair
chr8_-_102181718 1.29 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chr5_-_169725231 1.29 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr9_-_125675576 1.28 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr8_-_23315190 1.27 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr10_+_51565188 1.27 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr7_+_4721885 1.24 ENST00000328914.4
FOXK1
forkhead box K1
chr22_-_42526802 1.20 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
CYP2D6
cytochrome P450, family 2, subfamily D, polypeptide 6
chr4_-_76912070 1.18 ENST00000395711.4
ENST00000356260.5
SDAD1
SDA1 domain containing 1
chr18_-_50240 1.17 ENST00000573909.1
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr5_+_156607829 1.11 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr5_-_171433819 1.11 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr5_-_131132658 1.11 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr1_+_203274639 1.08 ENST00000290551.4
BTG2
BTG family, member 2
chr6_+_292051 1.07 ENST00000344450.5
DUSP22
dual specificity phosphatase 22
chr14_+_88471468 1.06 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr11_+_118175596 1.04 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr22_+_37678424 1.03 ENST00000248901.6
CYTH4
cytohesin 4
chr8_+_119294456 1.03 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr12_+_12223867 1.02 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr2_-_183387430 1.01 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr2_-_158345462 1.00 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr1_+_158149737 0.98 ENST00000368171.3
CD1D
CD1d molecule
chr11_-_62359027 0.98 ENST00000494385.1
ENST00000308436.7
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr3_+_113251143 0.94 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr15_-_58306295 0.91 ENST00000559517.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr4_-_159094194 0.89 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr11_-_44972418 0.84 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
TP53I11
tumor protein p53 inducible protein 11
chr15_-_89755034 0.83 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr16_-_20364122 0.81 ENST00000396138.4
ENST00000577168.1
UMOD
uromodulin
chr1_+_104198377 0.81 ENST00000370083.4
AMY1A
amylase, alpha 1A (salivary)
chrX_+_101975643 0.80 ENST00000361229.4
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr1_+_17559776 0.80 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chrX_+_101975619 0.79 ENST00000457056.1
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr4_+_2470664 0.76 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr5_+_118812237 0.76 ENST00000513628.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr11_+_118175132 0.75 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr19_+_45542773 0.75 ENST00000544944.2
CLASRP
CLK4-associating serine/arginine rich protein
chr20_+_57226841 0.73 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr22_+_47070490 0.73 ENST00000408031.1
GRAMD4
GRAM domain containing 4
chr6_+_135502501 0.73 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_-_89744365 0.72 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr19_+_55417499 0.72 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr17_-_7017559 0.71 ENST00000446679.2
ASGR2
asialoglycoprotein receptor 2
chr1_+_12524965 0.70 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr11_+_89764274 0.70 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr7_+_140396756 0.70 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chrX_+_107288239 0.70 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr18_-_44561988 0.69 ENST00000332567.4
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr15_-_50557863 0.68 ENST00000543581.1
HDC
histidine decarboxylase
chr19_+_39390320 0.64 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_+_241807870 0.63 ENST00000307503.3
AGXT
alanine-glyoxylate aminotransferase
chr15_-_80189380 0.63 ENST00000258874.3
MTHFS
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chrX_+_76709648 0.62 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr11_-_134123142 0.61 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1
thymocyte nuclear protein 1
chr8_-_38239732 0.61 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr16_-_4896205 0.60 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr4_+_88720698 0.59 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chrX_+_107288197 0.59 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr3_-_46069223 0.58 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr10_-_5446786 0.58 ENST00000479328.1
ENST00000380419.3
TUBAL3
tubulin, alpha-like 3
chr6_-_31648150 0.57 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr17_-_34344991 0.56 ENST00000591423.1
CCL23
chemokine (C-C motif) ligand 23
chr4_-_89744314 0.56 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr1_+_146714291 0.55 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr12_-_40013553 0.55 ENST00000308666.3
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr6_-_25874440 0.54 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr3_-_46608010 0.54 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr2_+_177053307 0.53 ENST00000331462.4
HOXD1
homeobox D1
chr3_-_101232019 0.53 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr2_-_97760576 0.52 ENST00000414820.1
ENST00000272610.3
FAHD2B
fumarylacetoacetate hydrolase domain containing 2B
chr12_+_4699244 0.50 ENST00000540757.2
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr3_+_122103014 0.50 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr1_-_8000872 0.49 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_-_160549235 0.49 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr1_+_196743912 0.48 ENST00000367425.4
CFHR3
complement factor H-related 3
chr18_+_32173276 0.47 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr3_+_119298429 0.47 ENST00000478927.1
ADPRH
ADP-ribosylarginine hydrolase
chr5_+_118812294 0.47 ENST00000509514.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr22_+_24999114 0.46 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr3_-_53916202 0.45 ENST00000335754.3
ACTR8
ARP8 actin-related protein 8 homolog (yeast)
chr2_-_79313973 0.45 ENST00000454188.1
REG1B
regenerating islet-derived 1 beta
chr19_-_37019562 0.45 ENST00000523638.1
ZNF260
zinc finger protein 260
chr11_+_59824060 0.43 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr19_-_20150252 0.42 ENST00000595736.1
ENST00000593468.1
ENST00000596019.1
ZNF682
zinc finger protein 682
chr6_+_163148161 0.42 ENST00000337019.3
ENST00000366889.2
PACRG
PARK2 co-regulated
chr19_-_20150301 0.41 ENST00000397165.2
ZNF682
zinc finger protein 682
chr7_+_64838786 0.40 ENST00000450302.2
ZNF92
zinc finger protein 92
chr5_-_75919253 0.38 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr11_-_88796803 0.36 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr5_+_180336564 0.34 ENST00000505126.1
ENST00000533815.2
BTNL8
butyrophilin-like 8
chr16_-_20364030 0.34 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
UMOD
uromodulin
chr3_+_118905564 0.33 ENST00000460625.1
UPK1B
uroplakin 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
2.1 21.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 4.9 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.6 8.0 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.4 4.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
1.4 4.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.2 9.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.1 5.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.9 5.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.9 5.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.7 2.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.7 5.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.7 7.8 GO:0006600 creatine metabolic process(GO:0006600)
0.7 3.4 GO:0061107 seminal vesicle development(GO:0061107)
0.6 1.9 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.6 6.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 9.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.6 1.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.5 1.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 1.6 GO:0032289 central nervous system myelin formation(GO:0032289) detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 1.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.4 2.0 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 4.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.4 6.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 1.8 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.4 1.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 2.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.3 1.2 GO:0033076 alkaloid catabolic process(GO:0009822) isoquinoline alkaloid metabolic process(GO:0033076) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.3 1.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.3 19.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 0.5 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.2 4.9 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.7 GO:0001694 histamine biosynthetic process(GO:0001694)
0.2 2.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.3 GO:0072757 cellular response to camptothecin(GO:0072757)
0.2 1.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.2 0.6 GO:0009078 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.2 1.2 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 1.4 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 3.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 1.0 GO:0016045 detection of bacterium(GO:0016045)
0.2 0.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 6.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 5.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 5.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.2 0.5 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.2 0.8 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 2.7 GO:0045651 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 0.6 GO:0015942 folic acid-containing compound catabolic process(GO:0009397) formate metabolic process(GO:0015942) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 1.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 2.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 2.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 3.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 3.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.9 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 2.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.4 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 3.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.2 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 1.5 GO:0006853 carnitine shuttle(GO:0006853)
0.1 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 1.8 GO:0006829 zinc II ion transport(GO:0006829)
0.1 1.6 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 1.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 1.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 3.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 3.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 3.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.5 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.6 GO:0030282 bone mineralization(GO:0030282)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 3.0 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 10.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.5 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.2 GO:0030213 negative regulation of fibroblast migration(GO:0010764) hyaluronan biosynthetic process(GO:0030213)
0.0 0.6 GO:0006295 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 1.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 1.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 4.3 GO:0006457 protein folding(GO:0006457)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0097180 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.1 8.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 9.4 GO:0045180 basal cortex(GO:0045180)
0.6 6.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 1.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.5 4.3 GO:0072687 meiotic spindle(GO:0072687)
0.4 2.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.4 11.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.4 3.2 GO:0016013 syntrophin complex(GO:0016013)
0.3 1.3 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.3 5.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 1.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 3.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 7.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 1.3 GO:0036398 TCR signalosome(GO:0036398)
0.3 4.3 GO:0043194 voltage-gated sodium channel complex(GO:0001518) axon initial segment(GO:0043194)
0.2 3.4 GO:0044754 autolysosome(GO:0044754)
0.2 9.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 25.9 GO:0043204 perikaryon(GO:0043204)
0.2 3.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 3.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 4.9 GO:0043034 costamere(GO:0043034)
0.1 7.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 2.2 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.2 GO:0098536 deuterosome(GO:0098536)
0.1 2.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 5.5 GO:0044306 neuron projection terminus(GO:0044306)
0.0 2.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 10.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 9.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.5 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 3.1 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.8 GO:0044297 cell body(GO:0044297)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 9.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.5 4.4 GO:0045322 unmethylated CpG binding(GO:0045322)
1.4 4.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.0 6.0 GO:0003998 acylphosphatase activity(GO:0003998)
1.0 8.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.9 6.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6 2.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.6 2.8 GO:0004359 glutaminase activity(GO:0004359)
0.5 2.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.5 1.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.5 11.2 GO:0002162 dystroglycan binding(GO:0002162)
0.4 1.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.4 3.4 GO:0032190 acrosin binding(GO:0032190)
0.4 1.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 8.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.3 6.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 0.6 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 0.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 1.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 1.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.3 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 10.1 GO:0030507 spectrin binding(GO:0030507)
0.2 3.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 1.2 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 0.8 GO:0016160 amylase activity(GO:0016160)
0.2 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 4.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.3 GO:0019863 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.2 3.6 GO:0000339 RNA cap binding(GO:0000339)
0.2 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 18.2 GO:0008013 beta-catenin binding(GO:0008013)
0.2 1.7 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 1.8 GO:0042608 T cell receptor binding(GO:0042608)
0.1 4.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.0 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 4.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0016918 retinal binding(GO:0016918)
0.1 3.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 5.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 3.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.2 GO:0070330 aromatase activity(GO:0070330)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 4.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.3 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 9.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 13.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 10.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.9 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.0 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 1.0 GO:0004540 ribonuclease activity(GO:0004540)
0.0 3.9 GO:0030695 GTPase regulator activity(GO:0030695)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.2 PID MYC PATHWAY C-MYC pathway
0.1 6.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 4.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 9.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 6.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 2.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 8.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 4.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 1.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 8.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 4.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 9.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 6.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 4.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 5.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production