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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 0.31

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
OLIG2
ENSG00000205927.4 oligodendrocyte transcription factor 2
NEUROD1
ENSG00000162992.3 neuronal differentiation 1
ATOH1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG2hg19_v2_chr21_+_34398153_343982500.491.2e-14Click!
NEUROD1hg19_v2_chr2_-_182545603_1825456030.221.3e-03Click!
ATOH1hg19_v2_chr4_+_94750014_947500420.162.1e-02Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_6309963 22.05 ENST00000382515.2
CD9
CD9 molecule
chr7_-_30029574 20.26 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1
secernin 1
chr7_-_30029367 20.10 ENST00000242059.5
SCRN1
secernin 1
chr12_+_6309517 19.69 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr3_-_195310802 19.60 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr10_-_15413035 17.78 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr5_+_102201722 15.19 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr4_+_113970772 14.06 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr10_-_73848764 13.81 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_102201509 13.44 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_102201687 13.42 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr10_-_62149433 13.27 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_30851840 12.70 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr5_+_173472607 12.61 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr19_-_49944806 12.59 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr16_+_23847267 12.56 ENST00000321728.7
PRKCB
protein kinase C, beta
chr2_-_175711133 12.24 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr4_+_114214125 11.95 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr12_-_123752624 11.75 ENST00000542174.1
ENST00000535796.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr3_+_159570722 11.41 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr16_-_21289627 11.17 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr1_+_10271674 11.16 ENST00000377086.1
KIF1B
kinesin family member 1B
chr1_+_92632542 10.97 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr10_-_73848531 10.30 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_+_26371763 9.78 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr16_+_56623433 9.57 ENST00000570176.1
MT3
metallothionein 3
chr9_-_140351928 9.54 ENST00000339554.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chrX_-_13835147 8.95 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr10_-_97321165 8.91 ENST00000306402.6
SORBS1
sorbin and SH3 domain containing 1
chr17_-_15168624 8.75 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr3_-_18480260 8.62 ENST00000454909.2
SATB1
SATB homeobox 1
chr15_+_63354769 8.54 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr19_-_51466681 8.54 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr5_+_102201430 8.48 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr17_+_77681075 8.40 ENST00000397549.2
CTD-2116F7.1
CTD-2116F7.1
chr1_+_226736446 8.32 ENST00000366788.3
ENST00000366789.4
C1orf95
chromosome 1 open reading frame 95
chrX_+_135278908 8.31 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr5_-_16936340 8.21 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr4_-_176733897 8.18 ENST00000393658.2
GPM6A
glycoprotein M6A
chr2_-_152830441 7.72 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr13_-_36705425 7.65 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chrX_-_13835461 7.48 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr11_-_66115032 7.32 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr16_+_23847339 7.22 ENST00000303531.7
PRKCB
protein kinase C, beta
chr16_+_6533729 7.02 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_+_41222998 6.70 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr5_-_171433579 6.65 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr1_+_36023035 6.48 ENST00000373253.3
NCDN
neurochondrin
chr3_+_111717511 6.46 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr4_+_1795012 6.23 ENST00000481110.2
ENST00000340107.4
ENST00000440486.2
ENST00000412135.2
FGFR3
fibroblast growth factor receptor 3
chr11_-_695162 5.94 ENST00000338675.6
DEAF1
DEAF1 transcription factor
chr1_+_171810606 5.78 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3
dynamin 3
chr1_+_50569575 5.61 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr14_+_90863327 5.55 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr5_-_171433819 5.52 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr1_+_169075554 5.42 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_1587166 5.39 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr2_-_2334888 5.38 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr10_-_97321112 5.36 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1
sorbin and SH3 domain containing 1
chr1_-_149889382 5.35 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr15_-_45670924 5.25 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_+_30852130 5.24 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_56385290 5.22 ENST00000564727.1
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr2_-_183903133 5.20 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chrX_+_135279179 5.16 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr22_-_36236623 5.08 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_+_93389425 4.94 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr2_-_241759622 4.78 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr8_+_9413410 4.68 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr19_-_47164386 4.59 ENST00000391916.2
ENST00000410105.2
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr12_+_122150646 4.48 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr19_-_39368887 4.36 ENST00000340740.3
ENST00000591812.1
RINL
Ras and Rab interactor-like
chr11_+_45918092 4.32 ENST00000395629.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr15_-_73925651 4.28 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr6_-_52860171 4.26 ENST00000370963.4
GSTA4
glutathione S-transferase alpha 4
chr17_-_1090599 4.23 ENST00000544583.2
ABR
active BCR-related
chr2_-_152830479 4.20 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr19_-_45826125 4.20 ENST00000221476.3
CKM
creatine kinase, muscle
chr19_+_36249057 4.19 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
C19orf55
chromosome 19 open reading frame 55
chr19_-_3772209 4.17 ENST00000555978.1
ENST00000555633.1
RAX2
retina and anterior neural fold homeobox 2
chr2_+_79740118 4.06 ENST00000496558.1
ENST00000451966.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr4_+_7045042 4.05 ENST00000310074.7
ENST00000512388.1
TADA2B
transcriptional adaptor 2B
chr6_-_52859968 4.01 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr14_+_100150622 4.00 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr16_+_6533380 3.99 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_97881429 3.96 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr10_-_69597810 3.93 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr12_-_48152853 3.90 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_133402410 3.85 ENST00000524381.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr12_+_49212514 3.80 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr12_+_6833237 3.80 ENST00000229251.3
ENST00000539735.1
ENST00000538410.1
COPS7A
COP9 signalosome subunit 7A
chr12_-_48152611 3.77 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chrX_-_73512411 3.77 ENST00000602576.1
ENST00000429124.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr1_+_50574585 3.77 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr19_+_18208603 3.70 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr1_+_159141397 3.64 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr14_+_90863364 3.62 ENST00000447653.3
ENST00000553542.1
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr3_-_45267760 3.52 ENST00000503771.1
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr17_+_44668035 3.47 ENST00000398238.4
ENST00000225282.8
NSF
N-ethylmaleimide-sensitive factor
chr6_+_30848557 3.45 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_-_69597915 3.43 ENST00000225171.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr7_-_31380502 3.39 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr15_+_43809797 3.38 ENST00000399453.1
ENST00000300231.5
MAP1A
microtubule-associated protein 1A
chr4_-_186877806 3.36 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr12_+_6833437 3.31 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COPS7A
COP9 signalosome subunit 7A
chr12_+_41086297 3.30 ENST00000551295.2
CNTN1
contactin 1
chr1_-_150669604 3.28 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr1_+_110527308 3.23 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr4_-_153303658 3.18 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr1_-_26233423 3.15 ENST00000357865.2
STMN1
stathmin 1
chr19_+_35521572 3.14 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr10_+_18429671 3.09 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_-_131644202 3.09 ENST00000320665.6
ENST00000436267.2
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chr22_-_38699003 3.01 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chrX_+_110187513 2.98 ENST00000446737.1
ENST00000425146.1
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr9_+_126773880 2.96 ENST00000373615.4
LHX2
LIM homeobox 2
chr19_+_18794470 2.95 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr18_-_53068911 2.91 ENST00000537856.3
TCF4
transcription factor 4
chr20_+_37434329 2.88 ENST00000299824.1
ENST00000373331.2
PPP1R16B
protein phosphatase 1, regulatory subunit 16B
chr2_+_173600514 2.88 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr22_-_36236265 2.84 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_+_96162242 2.78 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr18_-_52989217 2.77 ENST00000570287.2
TCF4
transcription factor 4
chr10_+_18429606 2.76 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr15_-_78526855 2.75 ENST00000541759.1
ENST00000558130.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr19_+_35521616 2.70 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr2_-_166930131 2.68 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_+_22963158 2.62 ENST00000438241.1
C1QA
complement component 1, q subcomponent, A chain
chr16_+_29674540 2.59 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr9_+_140033862 2.59 ENST00000350902.5
ENST00000371550.4
ENST00000371546.4
ENST00000371555.4
ENST00000371553.3
ENST00000371559.4
ENST00000371560.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr6_-_33385902 2.59 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr3_-_10547333 2.57 ENST00000383800.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr1_+_17559776 2.52 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr5_-_138210977 2.47 ENST00000274711.6
ENST00000521094.2
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr17_-_2996290 2.46 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chrX_-_73512177 2.43 ENST00000603672.1
ENST00000418855.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr4_-_186877502 2.41 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr12_-_49393092 2.39 ENST00000421952.2
DDN
dendrin
chr9_-_14313641 2.34 ENST00000380953.1
NFIB
nuclear factor I/B
chrX_-_63005405 2.33 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_-_48152428 2.33 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr22_+_19705928 2.28 ENST00000383045.3
ENST00000438754.2
SEPT5
septin 5
chr15_-_42749711 2.22 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr12_-_49351303 2.22 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr3_-_52002403 2.19 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr11_-_71639670 2.17 ENST00000533047.1
ENST00000529844.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr3_-_10547192 2.16 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr18_-_53069419 2.16 ENST00000570177.2
TCF4
transcription factor 4
chr10_-_72141330 2.16 ENST00000395011.1
ENST00000395010.1
LRRC20
leucine rich repeat containing 20
chr19_-_4454081 2.15 ENST00000591919.1
UBXN6
UBX domain protein 6
chr6_+_44184653 2.15 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
RP1-302G2.5
chrX_+_54835493 2.13 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr10_-_116444371 2.12 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr3_+_42897512 2.09 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr12_+_120933859 2.08 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr17_-_3301704 2.06 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr13_+_35516390 2.04 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
NBEA
neurobeachin
chr12_+_53491220 2.04 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr6_-_112194484 2.02 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr20_+_57875658 2.02 ENST00000371025.3
EDN3
endothelin 3
chr19_-_4338783 1.98 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr6_+_29555683 1.96 ENST00000383640.2
OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr3_+_183892635 1.96 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_6720686 1.95 ENST00000245907.6
C3
complement component 3
chr1_-_226111929 1.94 ENST00000343818.6
ENST00000432920.2
PYCR2
RP4-559A3.7
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chr11_+_32112431 1.93 ENST00000054950.3
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr11_+_46299199 1.91 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr8_-_141774467 1.90 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr19_+_15852203 1.89 ENST00000305892.1
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr9_+_92219919 1.83 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr10_+_7745303 1.83 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_15160130 1.82 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr17_-_73892992 1.82 ENST00000540128.1
ENST00000269383.3
TRIM65
tripartite motif containing 65
chr17_-_3195876 1.81 ENST00000323404.1
OR3A1
olfactory receptor, family 3, subfamily A, member 1
chrX_+_100474711 1.81 ENST00000402866.1
DRP2
dystrophin related protein 2
chr11_+_117073850 1.81 ENST00000529622.1
TAGLN
transgelin
chr13_+_88324870 1.79 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr19_-_46285736 1.78 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr13_+_38923959 1.77 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr18_-_52989525 1.77 ENST00000457482.3
TCF4
transcription factor 4
chr12_+_120933904 1.75 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr2_-_154335300 1.75 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr1_+_15272271 1.73 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr1_+_155051305 1.73 ENST00000368408.3
EFNA3
ephrin-A3
chr14_-_75079026 1.72 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr6_+_96463840 1.71 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr1_-_36022979 1.68 ENST00000469892.1
ENST00000325722.3
KIAA0319L
KIAA0319-like
chr12_+_101988627 1.68 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr4_-_186733363 1.67 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr20_+_42839722 1.67 ENST00000442383.1
ENST00000435163.1
OSER1-AS1
OSER1 antisense RNA 1 (head to head)
chr7_+_75931861 1.65 ENST00000248553.6
HSPB1
heat shock 27kDa protein 1
chr2_+_11052054 1.64 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr12_+_56473628 1.62 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr17_+_11924129 1.62 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr9_-_131644306 1.60 ENST00000302586.3
CCBL1
cysteine conjugate-beta lyase, cytoplasmic
chrX_-_11445856 1.57 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr4_-_46391805 1.56 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chrX_+_100474906 1.54 ENST00000541709.1
DRP2
dystrophin related protein 2
chr12_-_52715179 1.52 ENST00000293670.3
KRT83
keratin 83
chr3_+_118905564 1.50 ENST00000460625.1
UPK1B
uroplakin 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 50.5 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
8.7 26.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
6.6 19.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
6.5 19.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
4.2 12.6 GO:0042137 sequestering of neurotransmitter(GO:0042137)
3.8 41.7 GO:0030913 paranodal junction assembly(GO:0030913)
3.7 11.2 GO:1904647 response to rotenone(GO:1904647)
3.6 21.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
3.3 13.3 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.2 9.6 GO:0097212 cadmium ion homeostasis(GO:0055073) lysosomal membrane organization(GO:0097212) negative regulation of hydrogen peroxide catabolic process(GO:2000296) regulation of oxygen metabolic process(GO:2000374)
2.5 10.0 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
2.5 4.9 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
1.9 5.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
1.9 5.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.6 16.4 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.6 4.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.4 4.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.4 4.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.4 5.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
1.3 7.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.2 9.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.1 24.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.1 3.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
1.0 11.2 GO:0006554 lysine catabolic process(GO:0006554)
1.0 5.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.0 2.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.9 2.6 GO:0043449 olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.9 9.4 GO:0006600 creatine metabolic process(GO:0006600)
0.8 9.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.8 3.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.7 2.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6 2.6 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.6 3.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.6 5.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.6 5.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.6 15.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.5 3.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.5 4.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 5.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 4.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.5 2.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.5 2.5 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 3.4 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 1.5 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.5 1.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.5 3.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 12.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 7.1 GO:0000338 protein deneddylation(GO:0000338)
0.4 8.6 GO:0060004 reflex(GO:0060004)
0.4 8.5 GO:0016540 protein autoprocessing(GO:0016540)
0.4 1.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.4 1.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.4 1.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.4 2.0 GO:0006311 meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060)
0.4 1.5 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.1 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 2.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 12.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.4 4.7 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.3 3.8 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 3.5 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.3 1.0 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.3 10.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.9 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 0.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 6.2 GO:0070977 bone maturation(GO:0070977)
0.3 11.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.3 5.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.3 2.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 5.7 GO:0032060 bleb assembly(GO:0032060)
0.3 1.2 GO:0007538 primary sex determination(GO:0007538)
0.3 1.7 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 3.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.3 0.8 GO:1990523 negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
0.3 2.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.3 1.9 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 11.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.3 0.8 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.3 3.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.3 8.3 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.3 16.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.3 1.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.3 6.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 1.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 5.9 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.2 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 1.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 1.9 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.2 11.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 1.7 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 5.6 GO:0048665 neuron fate specification(GO:0048665)
0.2 2.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 3.8 GO:0008038 neuron recognition(GO:0008038)
0.2 4.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 0.9 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.2 1.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 1.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 0.7 GO:0036269 swimming behavior(GO:0036269)
0.2 0.7 GO:0097325 melanocyte proliferation(GO:0097325)
0.2 0.8 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.2 0.8 GO:0009624 response to nematode(GO:0009624)
0.2 7.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.7 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 2.7 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 3.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.6 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.1 1.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 1.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 5.2 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 6.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 11.7 GO:0030516 regulation of axon extension(GO:0030516)
0.1 3.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 3.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.3 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.3 GO:2000609 thyroid-stimulating hormone secretion(GO:0070460) metanephric comma-shaped body morphogenesis(GO:0072278) regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.7 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.1 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.3 GO:0060454 detection of temperature stimulus involved in thermoception(GO:0050960) detection of chemical stimulus involved in sensory perception of pain(GO:0050968) positive regulation of gastric acid secretion(GO:0060454) response to capsazepine(GO:1901594)
0.1 1.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 3.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.6 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 2.0 GO:0007625 grooming behavior(GO:0007625)
0.1 3.7 GO:0010039 response to iron ion(GO:0010039)
0.1 0.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 2.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 1.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.3 GO:0048535 lymph node development(GO:0048535)
0.1 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 6.9 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.1 3.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.6 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 1.1 GO:0033622 integrin activation(GO:0033622)
0.1 1.9 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.1 0.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 1.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.6 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 8.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 2.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.7 GO:0097435 fibril organization(GO:0097435)
0.0 4.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 1.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.0 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 4.8 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 1.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 2.0 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.7 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.7 GO:0021542 dentate gyrus development(GO:0021542)
0.0 2.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.9 GO:0038096 Fc receptor mediated stimulatory signaling pathway(GO:0002431) immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.8 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.7 GO:0051693 actin filament capping(GO:0051693)
0.0 0.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 1.3 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.1 GO:0046903 secretion(GO:0046903)
0.0 0.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 3.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.3 GO:0005899 insulin receptor complex(GO:0005899)
1.6 12.6 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
1.3 41.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.2 5.8 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.0 9.6 GO:0097449 astrocyte projection(GO:0097449)
0.9 16.0 GO:0043194 axon initial segment(GO:0043194)
0.8 9.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.7 3.7 GO:0005602 complement component C1 complex(GO:0005602)
0.7 8.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6 4.9 GO:0042583 chromaffin granule(GO:0042583)
0.6 12.2 GO:0044295 axonal growth cone(GO:0044295)
0.5 25.2 GO:0043034 costamere(GO:0043034)
0.5 11.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 3.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 9.5 GO:0097440 apical dendrite(GO:0097440)
0.4 8.2 GO:0032433 filopodium tip(GO:0032433)
0.4 2.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.4 5.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 6.9 GO:0032059 bleb(GO:0032059)
0.4 2.0 GO:0000801 central element(GO:0000801)
0.4 4.3 GO:0060077 inhibitory synapse(GO:0060077)
0.4 57.5 GO:0043204 perikaryon(GO:0043204)
0.4 1.4 GO:1990745 EARP complex(GO:1990745)
0.3 3.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 9.4 GO:0043218 compact myelin(GO:0043218)
0.3 1.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 11.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 5.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 4.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 10.8 GO:1904115 axon cytoplasm(GO:1904115)
0.2 7.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 2.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 10.3 GO:0008180 COP9 signalosome(GO:0008180)
0.2 8.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 9.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 10.2 GO:0005902 microvillus(GO:0005902)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.0 GO:0030914 STAGA complex(GO:0030914)
0.1 0.8 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 3.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.0 GO:0036020 endolysosome membrane(GO:0036020)
0.1 2.7 GO:0032982 myosin filament(GO:0032982)
0.1 5.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0008091 spectrin(GO:0008091)
0.1 3.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 3.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.5 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 21.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 12.0 GO:0030027 lamellipodium(GO:0030027)
0.1 1.4 GO:0031091 platelet alpha granule(GO:0031091) platelet alpha granule lumen(GO:0031093)
0.1 4.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 10.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 5.3 GO:0005776 autophagosome(GO:0005776)
0.1 7.2 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.4 GO:0030057 desmosome(GO:0030057)
0.0 7.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0005884 actin filament(GO:0005884)
0.0 10.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 18.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.3 GO:0043195 terminal bouton(GO:0043195)
0.0 8.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 5.3 GO:0001726 ruffle(GO:0001726)
0.0 8.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0097542 ciliary tip(GO:0097542)
0.0 12.9 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 7.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 7.5 GO:0005925 focal adhesion(GO:0005925)
0.0 2.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 6.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.8 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 50.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
6.6 19.8 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
4.3 21.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
3.3 9.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
3.1 12.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
2.8 11.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
1.9 5.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.6 40.4 GO:0016805 dipeptidase activity(GO:0016805)
1.4 12.6 GO:0032051 clathrin light chain binding(GO:0032051)
1.1 6.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.1 22.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.1 4.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.0 7.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.0 1.9 GO:0035497 cAMP response element binding(GO:0035497)
0.9 4.6 GO:0070097 delta-catenin binding(GO:0070097)
0.9 8.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.9 2.6 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.8 37.2 GO:0030507 spectrin binding(GO:0030507)
0.8 10.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7 9.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 18.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 9.5 GO:0046870 cadmium ion binding(GO:0046870)
0.6 6.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.6 3.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.6 1.7 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.5 4.2 GO:0004111 creatine kinase activity(GO:0004111)
0.5 2.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 1.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.5 1.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 5.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 2.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 3.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.4 5.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 1.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.4 2.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 6.2 GO:0008432 JUN kinase binding(GO:0008432)
0.4 19.6 GO:0015485 cholesterol binding(GO:0015485)
0.3 5.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 11.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 7.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 14.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 15.2 GO:0005158 insulin receptor binding(GO:0005158)
0.3 2.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 10.1 GO:0017091 AU-rich element binding(GO:0017091)
0.3 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 0.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 3.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0099583 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 3.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 11.2 GO:0019894 kinesin binding(GO:0019894)
0.2 1.1 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 3.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 5.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 36.5 GO:0005178 integrin binding(GO:0005178)
0.2 2.7 GO:0031432 titin binding(GO:0031432)
0.2 2.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 4.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 7.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 1.6 GO:0038132 neuregulin binding(GO:0038132)
0.2 25.3 GO:0044325 ion channel binding(GO:0044325)
0.2 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 7.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 3.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 9.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 3.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 3.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 15.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.9 GO:0030552 cAMP binding(GO:0030552)
0.1 0.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.3 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 7.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 3.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 11.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 10.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 3.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 4.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.7 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.7 GO:0019838 growth factor binding(GO:0019838)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 51.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.4 24.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 9.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 2.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3 5.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 12.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.3 15.4 PID INSULIN PATHWAY Insulin Pathway
0.2 13.6 PID ATR PATHWAY ATR signaling pathway
0.2 4.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 5.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 3.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 5.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 4.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.2 PID FGF PATHWAY FGF signaling pathway
0.1 8.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 7.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 5.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.0 PID ARF 3PATHWAY Arf1 pathway
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 25.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.5 17.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 6.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.5 12.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.5 29.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.5 14.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 11.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 4.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 4.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 3.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 12.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 4.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 14.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 8.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 7.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 30.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 12.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 6.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 4.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 4.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.5 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 10.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 5.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 5.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 5.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)