Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for OLIG3_NEUROD2_NEUROG2
Z-value: 0.21
Motif logo
Transcription factors associated with OLIG3_NEUROD2_NEUROG2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000177468.5 | oligodendrocyte transcription factor 3 | |
| ENSG00000171532.4 | neuronal differentiation 2 | |
| ENSG00000178403.3 | neurogenin 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NEUROG2 | hg19_v2_chr4_-_113437328_113437337 | 0.09 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_195310802 Show fit | 11.60 |
ENST00000421243.1
ENST00000453131.1 |
apolipoprotein D |
|
| chr19_-_37019562 Show fit | 9.13 |
ENST00000523638.1
|
zinc finger protein 260 |
|
| chr12_-_91573132 Show fit | 9.01 |
ENST00000550563.1
ENST00000546370.1 |
decorin |
|
| chr11_+_92085707 Show fit | 8.95 |
ENST00000525166.1
|
FAT atypical cadherin 3 |
|
| chrX_+_69509927 Show fit | 7.37 |
ENST00000374403.3
|
kinesin family member 4A |
|
| chr12_-_91573249 Show fit | 7.10 |
ENST00000550099.1
ENST00000546391.1 ENST00000551354.1 |
decorin |
|
| chr14_-_69864993 Show fit | 5.82 |
ENST00000555373.1
|
enhancer of rudimentary homolog (Drosophila) |
|
| chr4_-_83719884 Show fit | 5.13 |
ENST00000282709.4
ENST00000273908.4 |
stearoyl-CoA desaturase 5 |
|
| chr12_-_91573316 Show fit | 5.12 |
ENST00000393155.1
|
decorin |
|
| chr21_-_34914394 Show fit | 5.08 |
ENST00000361093.5
ENST00000381815.4 |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
Network of associatons between targets according to the STRING database.
First level regulatory network of OLIG3_NEUROD2_NEUROG2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 26.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.4 | 12.3 | GO:1904707 | positive regulation of vascular smooth muscle cell proliferation(GO:1904707) |
| 3.9 | 11.6 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.1 | 10.4 | GO:0070125 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 2.0 | 8.1 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 0.6 | 6.4 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.4 | 6.4 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 5.8 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 5.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 5.4 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 26.2 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.1 | 18.4 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.1 | 16.0 | GO:0030016 | myofibril(GO:0030016) |
| 0.2 | 8.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.2 | 7.4 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 6.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.8 | 5.4 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.3 | 5.4 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 5.3 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.3 | 5.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 26.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 3.1 | 12.3 | GO:1904408 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408) |
| 0.2 | 11.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 9.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 7.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 1.2 | 6.2 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.1 | 6.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.2 | 5.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 5.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 5.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 27.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 6.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 5.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 3.7 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 3.6 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 3.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 3.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 3.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.1 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 2.3 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 25.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 7.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 6.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 5.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.4 | 5.4 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.2 | 5.4 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 5.4 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.3 | 5.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 4.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 4.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |