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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for ONECUT1

Z-value: 0.08

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Transcription factors associated with ONECUT1

Gene Symbol Gene ID Gene Info
ONECUT1
ENSG00000169856.7 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT1hg19_v2_chr15_-_53082178_53082209-0.063.7e-01Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_116840728 12.00 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_26697304 11.97 ENST00000536498.1
VTN
vitronectin
chr3_+_52811596 9.55 ENST00000542827.1
ENST00000273283.2
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr13_-_46679144 8.21 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679185 8.19 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr5_-_176836577 7.54 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr19_+_45449301 7.48 ENST00000591597.1
APOC2
apolipoprotein C-II
chr17_-_64225508 6.80 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_+_207262881 6.38 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr19_+_45449228 6.38 ENST00000252490.4
APOC2
apolipoprotein C-II
chr1_+_159557607 6.37 ENST00000255040.2
APCS
amyloid P component, serum
chr2_+_234959323 6.17 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr19_+_45449266 5.96 ENST00000592257.1
APOC2
apolipoprotein C-II
chr11_+_57365150 5.91 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr13_+_30002846 5.83 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr9_-_14180778 5.32 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr3_+_186383741 4.96 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr1_+_57320437 4.78 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr3_-_170744498 4.46 ENST00000382808.4
ENST00000314251.3
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chrX_+_70435044 4.13 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1
gap junction protein, beta 1, 32kDa
chr17_-_17485731 4.09 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr1_+_207262540 4.08 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr1_-_25747283 3.94 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE
Rh blood group, CcEe antigens
chr3_+_142315225 3.92 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr9_-_138853156 3.87 ENST00000371756.3
UBAC1
UBA domain containing 1
chr2_+_234959376 3.62 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr1_+_26496362 3.59 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr10_+_115312766 3.38 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr19_+_2785458 3.34 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr1_+_207262578 3.32 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr1_+_207262627 3.14 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr4_-_157892498 3.06 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr7_-_6523688 2.95 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_+_234600253 2.84 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_+_41052808 2.82 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr10_-_127505167 2.82 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr8_+_82192501 2.80 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr22_-_36220420 2.70 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_121457608 2.57 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr17_-_56082455 2.48 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr10_+_28966271 2.46 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr1_+_25599018 2.43 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr13_-_107187462 2.42 ENST00000245323.4
EFNB2
ephrin-B2
chr9_+_140135665 2.23 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr1_+_25598872 2.18 ENST00000328664.4
RHD
Rh blood group, D antigen
chr12_+_69742121 2.17 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr2_-_85788652 2.11 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr20_-_22566089 1.96 ENST00000377115.4
FOXA2
forkhead box A2
chr1_+_25598989 1.95 ENST00000454452.2
RHD
Rh blood group, D antigen
chr10_+_98064085 1.84 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chr10_+_51576285 1.77 ENST00000443446.1
NCOA4
nuclear receptor coactivator 4
chr1_-_165668100 1.66 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr3_+_148415571 1.64 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr3_-_24207039 1.64 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr19_+_5681153 1.58 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr8_-_101718991 1.57 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr21_-_27107344 1.56 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_-_151804314 1.52 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr21_-_27107198 1.48 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chrX_+_119737806 1.47 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr15_-_99789736 1.39 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr1_-_151804222 1.38 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr6_-_27799305 1.32 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr12_+_111471828 1.31 ENST00000261726.6
CUX2
cut-like homeobox 2
chr16_+_27214802 1.28 ENST00000380948.2
ENST00000286096.4
KDM8
lysine (K)-specific demethylase 8
chr7_+_99425633 1.25 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr21_-_27107283 1.23 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr8_-_101719159 1.19 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr22_-_37505588 1.18 ENST00000406856.1
TMPRSS6
transmembrane protease, serine 6
chr9_-_2844058 1.18 ENST00000397885.2
KIAA0020
KIAA0020
chr13_-_114018400 1.13 ENST00000375430.4
ENST00000375431.4
GRTP1
growth hormone regulated TBC protein 1
chr19_+_13135386 1.11 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_70980051 1.09 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr3_-_99569821 1.07 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr9_+_130565487 1.04 ENST00000373225.3
ENST00000431857.1
FPGS
folylpolyglutamate synthase
chr8_-_23712312 1.02 ENST00000290271.2
STC1
stanniocalcin 1
chr12_-_11422739 0.99 ENST00000279573.7
PRB3
proline-rich protein BstNI subfamily 3
chr14_+_101299520 0.96 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr5_+_32585605 0.94 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr16_-_18573396 0.93 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NOMO2
NODAL modulator 2
chr21_-_30445886 0.89 ENST00000431234.1
ENST00000540844.1
ENST00000286788.4
CCT8
chaperonin containing TCP1, subunit 8 (theta)
chr11_+_62623544 0.88 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr18_-_31802056 0.86 ENST00000538587.1
NOL4
nucleolar protein 4
chr22_-_37505449 0.86 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr8_-_27468842 0.82 ENST00000523500.1
CLU
clusterin
chr1_+_156756667 0.82 ENST00000526188.1
ENST00000454659.1
PRCC
papillary renal cell carcinoma (translocation-associated)
chr16_+_16326352 0.82 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3
NODAL modulator 3
chr4_-_103747011 0.81 ENST00000350435.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_32529973 0.81 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_114133773 0.81 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_-_95209 0.79 ENST00000332708.5
ENST00000309812.4
TUBB8
tubulin, beta 8 class VIII
chr4_-_175443484 0.79 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_-_103746924 0.78 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_-_54653313 0.78 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr1_-_116383322 0.78 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr18_-_49557 0.77 ENST00000308911.6
RP11-683L23.1
Tubulin beta-8 chain-like protein LOC260334
chr13_+_52598827 0.76 ENST00000521776.2
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr4_+_107237660 0.75 ENST00000394701.4
AIMP1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr19_-_47287990 0.74 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chrX_-_110654147 0.74 ENST00000358070.4
DCX
doublecortin
chr12_-_108954933 0.74 ENST00000431469.2
ENST00000546815.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr13_+_111267866 0.73 ENST00000458711.2
ENST00000424185.2
ENST00000397191.4
ENST00000309957.2
CARKD
carbohydrate kinase domain containing
chr11_+_62623621 0.73 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_79816965 0.73 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_94003003 0.71 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr9_-_77703056 0.68 ENST00000376811.1
NMRK1
nicotinamide riboside kinase 1
chr1_-_52870059 0.67 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr1_-_52870104 0.67 ENST00000371568.3
ORC1
origin recognition complex, subunit 1
chr7_+_102937869 0.66 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
PMPCB
peptidase (mitochondrial processing) beta
chr19_-_49243845 0.65 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr14_-_35873856 0.63 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr11_+_19799327 0.62 ENST00000540292.1
NAV2
neuron navigator 2
chr22_-_32146106 0.61 ENST00000327423.6
ENST00000397493.2
ENST00000434485.1
ENST00000412743.1
PRR14L
proline rich 14-like
chr4_+_159131630 0.60 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr15_-_38519066 0.60 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr4_-_111563076 0.59 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chrX_+_123095155 0.59 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chr2_+_71127699 0.58 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr11_+_131240373 0.55 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr2_+_241375069 0.54 ENST00000264039.2
GPC1
glypican 1
chr11_+_30253410 0.52 ENST00000533718.1
FSHB
follicle stimulating hormone, beta polypeptide
chr14_+_24422795 0.49 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr12_-_11422630 0.49 ENST00000381842.3
ENST00000538488.1
PRB3
proline-rich protein BstNI subfamily 3
chr14_-_27066960 0.48 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr4_+_169418195 0.48 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr11_-_95657231 0.47 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2
myotubularin related protein 2
chr3_-_46735132 0.46 ENST00000415953.1
ALS2CL
ALS2 C-terminal like
chr11_-_19223523 0.46 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr22_+_39101728 0.45 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr7_-_154794763 0.45 ENST00000404141.1
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr12_-_13529642 0.45 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr4_-_103746683 0.44 ENST00000504211.1
ENST00000508476.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr9_-_77703115 0.44 ENST00000361092.4
ENST00000376808.4
NMRK1
nicotinamide riboside kinase 1
chr7_+_141463897 0.44 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr1_-_94586651 0.43 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_161695042 0.43 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr17_+_53342311 0.42 ENST00000226067.5
HLF
hepatic leukemia factor
chr10_+_60028818 0.42 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr6_-_161695074 0.41 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr18_-_31802282 0.38 ENST00000535475.1
NOL4
nucleolar protein 4
chr2_-_214016314 0.37 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr21_-_43816152 0.36 ENST00000433957.2
ENST00000398397.3
TMPRSS3
transmembrane protease, serine 3
chr6_+_29079668 0.36 ENST00000377169.1
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr12_-_11062161 0.34 ENST00000390677.2
TAS2R13
taste receptor, type 2, member 13
chr12_-_10978957 0.33 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr12_+_15475331 0.33 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr12_+_74931551 0.31 ENST00000519948.2
ATXN7L3B
ataxin 7-like 3B
chr1_-_32384693 0.31 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr4_+_169418255 0.31 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr21_-_43735628 0.30 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr21_-_43816052 0.30 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr8_-_145028013 0.29 ENST00000354958.2
PLEC
plectin
chr11_-_67407031 0.29 ENST00000335385.3
TBX10
T-box 10
chr19_+_11200038 0.28 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr5_+_169780485 0.28 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr22_+_24198890 0.28 ENST00000345044.6
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr20_+_36373032 0.26 ENST00000373473.1
CTNNBL1
catenin, beta like 1
chr22_-_26961328 0.26 ENST00000398110.2
TPST2
tyrosylprotein sulfotransferase 2
chr19_+_45596218 0.26 ENST00000421905.1
ENST00000221462.4
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr19_+_45596398 0.25 ENST00000544069.2
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr7_+_101459263 0.25 ENST00000292538.4
ENST00000393824.3
ENST00000547394.2
ENST00000360264.3
ENST00000425244.2
CUX1
cut-like homeobox 1
chrX_+_14547632 0.24 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr19_-_45873642 0.24 ENST00000485403.2
ENST00000586856.1
ENST00000586131.1
ENST00000391940.4
ENST00000221481.6
ENST00000391944.3
ENST00000391945.4
ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
chrX_-_108725301 0.24 ENST00000218006.2
GUCY2F
guanylate cyclase 2F, retinal
chr3_-_46735155 0.23 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr19_+_33865218 0.23 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr5_+_119799927 0.22 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr8_-_33370607 0.20 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr12_-_108955070 0.20 ENST00000228284.3
ENST00000546611.1
SART3
squamous cell carcinoma antigen recognized by T cells 3
chr12_+_15475462 0.18 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr3_+_181429704 0.18 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chrX_+_122318006 0.17 ENST00000371266.1
ENST00000264357.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chrX_+_10124977 0.17 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr11_+_118938485 0.16 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_+_140800638 0.15 ENST00000398587.2
ENST00000518882.1
PCDHGA11
protocadherin gamma subfamily A, 11
chr4_+_187187098 0.15 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr11_-_122930121 0.13 ENST00000524552.1
HSPA8
heat shock 70kDa protein 8
chr11_+_102188272 0.12 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chrX_-_151143140 0.11 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr6_-_31651817 0.10 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chrX_-_131623982 0.08 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr1_+_153232160 0.07 ENST00000368742.3
LOR
loricrin
chr10_-_35104185 0.06 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr1_+_212738676 0.06 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr11_-_72385437 0.06 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_+_50571949 0.05 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr11_+_4788500 0.05 ENST00000380390.1
MMP26
matrix metallopeptidase 26
chr11_+_134123389 0.05 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
ACAD8
acyl-CoA dehydrogenase family, member 8
chr11_+_60995849 0.04 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chrX_-_33229636 0.02 ENST00000357033.4
DMD
dystrophin
chr16_+_31044413 0.02 ENST00000394998.1
STX4
syntaxin 4
chr15_-_89089860 0.01 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1
de-etiolated homolog 1 (Arabidopsis)
chr4_+_76649797 0.00 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.6 19.8 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
4.1 16.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
2.5 7.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.9 16.9 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
1.5 4.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.5 11.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.3 12.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.3 6.4 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.8 12.0 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.8 3.9 GO:1902896 terminal web assembly(GO:1902896)
0.8 5.3 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 2.8 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.7 5.9 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.7 2.0 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.5 1.6 GO:0008050 female courtship behavior(GO:0008050)
0.5 4.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.5 1.5 GO:0002188 translation reinitiation(GO:0002188)
0.4 2.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 3.6 GO:1903026 ribosomal large subunit export from nucleus(GO:0000055) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 2.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 1.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 2.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 2.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 4.1 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.4 10.5 GO:0015695 organic cation transport(GO:0015695)
0.3 1.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 1.6 GO:0060356 leucine import(GO:0060356)
0.3 2.8 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 2.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.7 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.2 4.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 3.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.2 0.7 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 0.5 GO:0090260 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 1.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 0.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.2 0.6 GO:0021564 vagus nerve development(GO:0021564)
0.1 9.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 2.5 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 2.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.8 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.0 GO:0097264 self proteolysis(GO:0097264)
0.1 4.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.5 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 2.9 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 10.3 GO:0046849 bone remodeling(GO:0046849)
0.1 0.6 GO:0070417 cellular response to cold(GO:0070417) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 3.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0090118 positive regulation of lipoprotein particle clearance(GO:0010986) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.7 GO:0001764 neuron migration(GO:0001764)
0.1 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.9 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 1.3 GO:0007614 short-term memory(GO:0007614)
0.1 2.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 1.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 1.8 GO:0033198 response to ATP(GO:0033198)
0.0 2.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.7 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 2.6 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 1.1 GO:0051156 carbohydrate phosphorylation(GO:0046835) glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 1.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.9 GO:0031648 protein destabilization(GO:0031648)
0.0 0.8 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 1.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.5 GO:0008038 neuron recognition(GO:0008038)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.5 19.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.9 16.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 3.9 GO:1990357 terminal web(GO:1990357)
0.5 4.8 GO:0005579 membrane attack complex(GO:0005579)
0.4 5.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 4.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 0.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 4.1 GO:0005922 connexon complex(GO:0005922)
0.2 5.0 GO:0036019 endolysosome(GO:0036019)
0.2 3.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 16.9 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 34.3 GO:0072562 blood microparticle(GO:0072562)
0.2 0.8 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 1.8 GO:0044754 autolysosome(GO:0044754)
0.1 3.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 8.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 4.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 8.8 GO:0005903 brush border(GO:0005903)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 2.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 3.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 17.7 GO:0005615 extracellular space(GO:0005615)
0.0 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 26.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
3.0 12.0 GO:0019862 IgA binding(GO:0019862)
1.5 4.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
1.4 4.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.2 3.6 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.8 12.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.8 6.4 GO:0001849 complement component C1q binding(GO:0001849)
0.7 2.9 GO:0005046 KDEL sequence binding(GO:0005046)
0.7 2.8 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.5 1.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 16.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 8.4 GO:0051787 misfolded protein binding(GO:0051787)
0.4 2.9 GO:0008142 oxysterol binding(GO:0008142)
0.4 2.2 GO:0003796 lysozyme activity(GO:0003796)
0.3 10.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 1.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.3 4.1 GO:0005243 gap junction channel activity(GO:0005243)
0.2 2.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 5.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 4.8 GO:0001848 complement binding(GO:0001848)
0.2 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 2.8 GO:0008494 translation activator activity(GO:0008494)
0.2 1.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.9 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 3.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 9.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 2.8 GO:0001972 retinoic acid binding(GO:0001972) glucuronosyltransferase activity(GO:0015020)
0.1 8.3 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.7 GO:0035925 translation repressor activity, nucleic acid binding(GO:0000900) mRNA 3'-UTR AU-rich region binding(GO:0035925) translation regulator activity, nucleic acid binding(GO:0090079)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 2.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.8 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 4.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 4.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 3.7 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 5.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 40.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 35.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 2.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 20.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.7 13.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 16.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 4.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 4.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 2.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 4.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 5.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 3.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 4.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 9.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 10.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 5.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 3.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins