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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for OSR1_OSR2

Z-value: 1.43

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Transcription factors associated with OSR1_OSR2

Gene Symbol Gene ID Gene Info
OSR1
ENSG00000143867.5 odd-skipped related transcription factor 1
OSR2
ENSG00000164920.5 odd-skipped related transciption factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OSR2hg19_v2_chr8_+_99956662_99956686-0.162.0e-02Click!

Activity profile of OSR1_OSR2 motif

Sorted Z-values of OSR1_OSR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_80942139 28.98 ENST00000521434.1
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr12_-_50419177 27.91 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
RACGAP1
Rac GTPase activating protein 1
chr5_+_68463043 27.73 ENST00000508407.1
ENST00000505500.1
CCNB1
cyclin B1
chr11_+_64808675 27.40 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr14_+_56127989 27.15 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr5_+_68462837 25.13 ENST00000256442.5
CCNB1
cyclin B1
chr5_+_68462944 24.64 ENST00000506572.1
CCNB1
cyclin B1
chr9_-_95055956 24.16 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr8_-_80942061 22.22 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr9_-_95056010 20.08 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr11_-_82997420 16.03 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr5_+_145826867 15.90 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr1_+_218458625 14.53 ENST00000366932.3
RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr2_-_37458749 13.24 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr9_+_36572851 12.84 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr7_+_73106926 12.33 ENST00000453316.1
WBSCR22
Williams Beuren syndrome chromosome region 22
chr10_-_43904608 11.43 ENST00000337970.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr15_-_66649010 11.35 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr17_-_79895097 11.03 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr17_-_79894651 10.44 ENST00000584848.1
ENST00000577756.1
ENST00000329875.8
PYCR1
pyrroline-5-carboxylate reductase 1
chr20_-_34330129 10.42 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RBM39
RNA binding motif protein 39
chr22_-_42336209 9.83 ENST00000472374.2
CENPM
centromere protein M
chr7_-_43769066 9.82 ENST00000223336.6
ENST00000310564.6
ENST00000431651.1
ENST00000415798.1
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr16_+_23690138 9.75 ENST00000300093.4
PLK1
polo-like kinase 1
chr19_-_13068012 9.70 ENST00000316939.1
GADD45GIP1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr10_-_43904235 9.53 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr17_-_79895154 9.41 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr7_-_43769051 9.37 ENST00000395880.3
COA1
cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
chr1_-_156722015 9.20 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr2_+_178257372 9.02 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase
chr16_-_66968055 8.93 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr2_-_74007193 8.61 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr3_+_149192475 8.61 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr15_+_66161802 8.15 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A
RAB11A, member RAS oncogene family
chr14_+_93651296 8.00 ENST00000283534.4
ENST00000557574.1
TMEM251
RP11-371E8.4
transmembrane protein 251
Uncharacterized protein
chr7_-_105752971 7.72 ENST00000011473.2
SYPL1
synaptophysin-like 1
chr20_+_31407692 7.61 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr9_+_112542591 7.27 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
PALM2
PALM2-AKAP2
AKAP2
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr5_+_169010638 7.20 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
SPDL1
spindle apparatus coiled-coil protein 1
chr3_-_50360192 6.95 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr8_+_125486939 6.68 ENST00000303545.3
RNF139
ring finger protein 139
chr7_+_134212312 6.66 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr5_+_36152091 6.45 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr2_-_88125471 6.27 ENST00000398146.3
RGPD2
RANBP2-like and GRIP domain containing 2
chr12_-_24102576 6.09 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5
SRY (sex determining region Y)-box 5
chr16_-_8962200 6.05 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr4_-_70080449 5.97 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chrX_-_134049262 5.94 ENST00000370783.3
MOSPD1
motile sperm domain containing 1
chr4_+_169013666 5.93 ENST00000359299.3
ANXA10
annexin A10
chr7_+_127228399 5.88 ENST00000000233.5
ENST00000415666.1
ARF5
ADP-ribosylation factor 5
chr15_-_41694640 5.87 ENST00000558719.1
ENST00000260361.4
ENST00000560978.1
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
chr5_+_70220768 5.83 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
SMN1
survival of motor neuron 1, telomeric
chr3_+_45927994 5.82 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr2_-_178257401 5.75 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr2_-_74735707 5.68 ENST00000233630.6
PCGF1
polycomb group ring finger 1
chr15_+_79603404 5.49 ENST00000299705.5
TMED3
transmembrane emp24 protein transport domain containing 3
chr5_+_36152163 5.39 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr5_+_69345350 5.27 ENST00000380741.4
ENST00000380743.4
ENST00000511812.1
ENST00000380742.4
SMN2
survival of motor neuron 2, centromeric
chr8_+_37594130 5.18 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2
ER lipid raft associated 2
chr5_-_140053152 5.02 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr2_-_201828356 5.00 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr15_+_66161871 4.78 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr8_+_26247878 4.55 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr19_-_16770915 4.51 ENST00000593459.1
ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
CTC-429P9.4
SMIM7
Small integral membrane protein 7; Uncharacterized protein
small integral membrane protein 7
chr4_+_146403912 4.50 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr3_+_193853927 4.39 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr3_+_149191723 4.30 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr9_+_33025209 4.29 ENST00000330899.4
ENST00000544625.1
DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr22_+_42017280 4.25 ENST00000402580.3
ENST00000428575.2
ENST00000359308.4
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr22_+_31489344 4.20 ENST00000404574.1
SMTN
smoothelin
chr2_-_148779106 4.18 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr15_+_66161792 4.08 ENST00000564910.1
ENST00000261890.2
RAB11A
RAB11A, member RAS oncogene family
chr19_+_39989535 3.97 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr1_-_35450897 3.85 ENST00000373337.3
ZMYM6NB
ZMYM6 neighbor
chr1_-_231560790 3.80 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr10_-_111683183 3.75 ENST00000403138.2
ENST00000369683.1
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr7_-_123197733 3.66 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr12_-_58165870 3.65 ENST00000257848.7
METTL1
methyltransferase like 1
chr1_+_42922173 3.65 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr11_+_62648336 3.62 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr22_+_42017459 3.50 ENST00000405878.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_+_89696692 3.38 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr12_-_15114492 3.34 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_+_19303008 3.30 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr3_+_179322481 3.29 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr19_+_7459998 3.27 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr15_+_75491213 2.96 ENST00000360639.2
C15orf39
chromosome 15 open reading frame 39
chr6_+_32938665 2.90 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr20_-_33999766 2.88 ENST00000349714.5
ENST00000438533.1
ENST00000359226.2
ENST00000374384.2
ENST00000374377.5
ENST00000407996.2
ENST00000424405.1
ENST00000542501.1
ENST00000397554.1
ENST00000540457.1
ENST00000374380.2
ENST00000374385.5
UQCC1
ubiquinol-cytochrome c reductase complex assembly factor 1
chr4_+_69681710 2.83 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_+_201798269 2.76 ENST00000361565.4
IPO9
importin 9
chr10_-_111683308 2.70 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr19_+_39989580 2.66 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr4_-_70361579 2.51 ENST00000512583.1
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr12_-_86650077 2.29 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_70361615 2.20 ENST00000305107.6
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr1_+_161736072 2.16 ENST00000367942.3
ATF6
activating transcription factor 6
chr2_-_183387064 2.12 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_-_153508460 2.10 ENST00000462776.2
S100A6
S100 calcium binding protein A6
chr6_+_152011628 2.01 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr15_+_58724184 1.96 ENST00000433326.2
LIPC
lipase, hepatic
chr9_-_21217310 1.90 ENST00000380216.1
IFNA16
interferon, alpha 16
chr21_+_40752170 1.85 ENST00000333781.5
ENST00000541890.1
WRB
tryptophan rich basic protein
chr4_+_151503077 1.83 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr1_+_144220127 1.80 ENST00000369373.5
NBPF8
neuroblastoma breakpoint family, member 8
chr15_+_41523335 1.76 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr18_+_616672 1.76 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr2_+_70056762 1.65 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr12_-_15114603 1.60 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_58166431 1.59 ENST00000333012.5
METTL21B
methyltransferase like 21B
chr2_-_183387283 1.49 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_+_101504200 1.47 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr8_-_145653885 1.42 ENST00000531032.1
ENST00000292510.4
ENST00000377348.2
ENST00000530790.1
ENST00000533806.1
VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chrX_+_80457442 1.29 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr2_-_183387430 1.19 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr15_+_41523417 1.07 ENST00000560397.1
CHP1
calcineurin-like EF-hand protein 1
chr7_-_144533074 1.02 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr18_+_616711 0.99 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr1_-_179112173 0.96 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr18_+_63417864 0.95 ENST00000536984.2
CDH7
cadherin 7, type 2
chr15_-_80263506 0.95 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr2_+_37458776 0.87 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr17_+_40714092 0.81 ENST00000420359.1
ENST00000449624.1
ENST00000585811.1
ENST00000585909.1
ENST00000586771.1
ENST00000421097.2
ENST00000591779.1
ENST00000587858.1
ENST00000587214.1
ENST00000587157.1
ENST00000590958.1
ENST00000393818.2
COASY
CoA synthase
chr12_-_86650045 0.79 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr17_+_36284791 0.78 ENST00000505415.1
TBC1D3F
TBC1 domain family, member 3F
chr17_-_7145475 0.77 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr4_-_113437328 0.74 ENST00000313341.3
NEUROG2
neurogenin 2
chr22_+_32870661 0.72 ENST00000266087.7
FBXO7
F-box protein 7
chr7_+_112090483 0.66 ENST00000403825.3
ENST00000429071.1
IFRD1
interferon-related developmental regulator 1
chr17_-_34756219 0.65 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr1_+_40505891 0.64 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr2_+_234580525 0.61 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_+_20054878 0.60 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr11_+_8704748 0.54 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr8_-_57906362 0.54 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr21_-_34915147 0.52 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr2_+_234580499 0.47 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr21_+_43919710 0.44 ENST00000398341.3
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr1_-_167487758 0.43 ENST00000362089.5
CD247
CD247 molecule
chr12_-_10251539 0.43 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr22_+_37309662 0.39 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr12_-_95467356 0.29 ENST00000393101.3
ENST00000333003.5
NR2C1
nuclear receptor subfamily 2, group C, member 1
chr5_+_76248538 0.22 ENST00000274368.4
CRHBP
corticotropin releasing hormone binding protein
chr11_-_102709441 0.20 ENST00000434103.1
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr13_-_72441315 0.16 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr5_-_125930929 0.14 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr16_+_83841448 0.07 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr19_+_36203830 0.03 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr6_+_10585979 0.02 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr4_-_8430152 0.01 ENST00000514423.1
ENST00000503233.1
ACOX3
acyl-CoA oxidase 3, pristanoyl

Network of associatons between targets according to the STRING database.

First level regulatory network of OSR1_OSR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
25.8 77.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
14.7 44.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
7.0 27.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
5.1 30.9 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
4.3 17.0 GO:0010796 regulation of multivesicular body size(GO:0010796)
3.0 9.0 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.5 7.6 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
2.4 11.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.3 11.4 GO:0048478 replication fork protection(GO:0048478)
2.2 6.7 GO:0016095 polyprenol catabolic process(GO:0016095)
2.0 9.8 GO:0016321 female meiosis chromosome segregation(GO:0016321)
1.9 9.7 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
1.7 7.0 GO:0019087 transformation of host cell by virus(GO:0019087)
1.6 4.7 GO:0006711 estrogen catabolic process(GO:0006711)
1.5 19.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.5 4.4 GO:0021558 midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
1.4 5.8 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
1.3 7.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
1.2 4.9 GO:0071461 cellular response to redox state(GO:0071461)
1.2 8.6 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.1 3.4 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
1.1 6.6 GO:0007386 compartment pattern specification(GO:0007386)
1.0 5.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.0 6.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.8 4.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.7 3.6 GO:0060356 leucine import(GO:0060356)
0.7 2.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.7 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.7 51.2 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.7 2.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.7 7.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.6 3.8 GO:0051342 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.6 6.5 GO:0010815 bradykinin catabolic process(GO:0010815)
0.5 4.3 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.5 5.8 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.5 14.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.4 7.0 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.4 2.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.4 6.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.4 8.9 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 2.8 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.3 9.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 5.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.3 1.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.3 2.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 4.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 6.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 12.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 19.4 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.2 0.7 GO:0007518 myoblast fate determination(GO:0007518)
0.2 0.9 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2 4.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 12.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 9.2 GO:0006270 DNA replication initiation(GO:0006270)
0.2 6.6 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 12.9 GO:0042246 tissue regeneration(GO:0042246)
0.1 2.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 5.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 26.2 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.5 GO:0051552 flavone metabolic process(GO:0051552)
0.1 9.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 4.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.7 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 0.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 3.6 GO:0006400 tRNA modification(GO:0006400)
0.1 0.2 GO:0097210 cellular response to cocaine(GO:0071314) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.9 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 7.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 6.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 21.6 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.6 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 2.0 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 2.8 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 10.9 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
15.5 77.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
5.6 27.9 GO:0097149 centralspindlin complex(GO:0097149)
3.4 17.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
3.3 9.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.1 44.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.9 51.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.7 5.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
1.6 7.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.5 8.9 GO:0071817 MMXD complex(GO:0071817)
1.3 7.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.3 11.4 GO:0031298 replication fork protection complex(GO:0031298)
1.2 7.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 3.6 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.7 5.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 19.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.6 4.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.6 6.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.5 5.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 14.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.5 7.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 7.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 6.0 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.3 4.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 9.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 12.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 11.9 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.2 12.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 2.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 19.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 3.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 9.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 9.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 5.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 4.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 17.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 18.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 18.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 11.7 GO:0005938 cell cortex(GO:0005938)
0.0 10.6 GO:0005819 spindle(GO:0005819)
0.0 4.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 2.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 13.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0098802 plasma membrane receptor complex(GO:0098802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 44.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
11.1 77.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
7.7 30.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
2.9 8.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.8 7.2 GO:0043515 kinetochore binding(GO:0043515)
1.7 7.0 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
1.7 6.7 GO:0047718 indanol dehydrogenase activity(GO:0047718)
1.6 9.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.9 27.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.8 7.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.7 4.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.7 17.0 GO:0031489 myosin V binding(GO:0031489)
0.6 25.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 23.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.6 6.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.5 9.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 4.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 3.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.4 3.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 4.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 23.3 GO:0019894 kinesin binding(GO:0019894)
0.4 14.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 3.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 5.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 3.8 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 6.6 GO:0005112 Notch binding(GO:0005112)
0.3 7.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 6.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 4.5 GO:0070411 I-SMAD binding(GO:0070411)
0.2 5.0 GO:0035198 miRNA binding(GO:0035198)
0.2 0.9 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.8 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 4.6 GO:0005521 lamin binding(GO:0005521)
0.2 4.5 GO:0071949 FAD binding(GO:0071949)
0.2 3.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 13.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 6.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 5.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 5.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 2.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 5.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 18.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 6.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 8.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 11.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 5.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 57.6 GO:0003723 RNA binding(GO:0003723)
0.0 2.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.4 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 101.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.0 44.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.6 17.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.5 27.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 7.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 10.4 PID ATR PATHWAY ATR signaling pathway
0.2 7.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 2.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 6.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 10.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 86.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.2 44.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.1 30.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.1 27.9 REACTOME KINESINS Genes involved in Kinesins
0.6 14.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.5 9.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 7.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 5.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.3 9.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 17.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 1.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 11.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 17.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 11.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 4.8 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.2 3.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 21.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 3.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 9.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 4.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling