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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for PAX8

Z-value: 0.18

Motif logo

Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
ENSG00000125618.12 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_113999274-0.064.0e-01Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_151938171 11.08 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
melanoma antigen family A, 3
chr1_-_27952741 10.05 ENST00000399173.1
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr14_-_106054659 7.63 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chrX_+_151867214 7.33 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
melanoma antigen family A, 6
chr6_-_27858570 7.30 ENST00000359303.2
histone cluster 1, H3j
chr2_+_90248739 6.52 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr11_-_58343319 6.12 ENST00000395074.2
leupaxin
chr2_+_90198535 5.31 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr2_-_211179883 5.19 ENST00000352451.3
myosin, light chain 1, alkali; skeletal, fast
chr22_+_22707260 5.11 ENST00000390293.1
immunoglobulin lambda variable 5-48 (non-functional)
chr11_+_117857063 4.99 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
interleukin 10 receptor, alpha
chr14_-_23288930 4.96 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_+_151903207 4.95 ENST00000370287.3
chondrosarcoma associated gene 1
chr19_+_42301079 4.86 ENST00000596544.1
carcinoembryonic antigen-related cell adhesion molecule 3
chr2_-_179672142 4.60 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr1_-_25256368 4.49 ENST00000308873.6
runt-related transcription factor 3
chr19_-_37701386 4.42 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
zinc finger protein 585B
chr6_-_44233361 4.34 ENST00000275015.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr6_+_160542870 4.04 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr14_-_107114267 4.02 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr6_-_134639180 3.95 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chrX_-_151903184 3.84 ENST00000357916.4
ENST00000393869.3
melanoma antigen family A, 12
chr1_-_161600990 3.66 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr22_+_21133469 3.55 ENST00000406799.1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_-_161600942 3.53 ENST00000421702.2
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr2_+_90259593 3.51 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chr10_+_135340859 3.50 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr17_+_1665345 3.48 ENST00000576406.1
ENST00000571149.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_123201337 3.45 ENST00000528880.2
hydroxycarboxylic acid receptor 3
chr1_+_161494036 3.41 ENST00000309758.4
heat shock 70kDa protein 6 (HSP70B')
chr10_+_70847852 3.36 ENST00000242465.3
serglycin
chr18_-_21017817 3.35 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
transmembrane protein 241
chr19_-_51538118 3.33 ENST00000529888.1
kallikrein-related peptidase 12
chr2_-_79313973 3.29 ENST00000454188.1
regenerating islet-derived 1 beta
chr12_-_123187890 3.28 ENST00000328880.5
hydroxycarboxylic acid receptor 2
chr1_-_161600822 3.25 ENST00000534776.1
ENST00000540048.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr19_-_52133588 3.21 ENST00000570106.2
sialic acid binding Ig-like lectin 5
chr6_+_160542821 3.11 ENST00000366963.4
solute carrier family 22 (organic cation transporter), member 1
chr11_+_60223312 3.11 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr6_+_14117872 3.08 ENST00000379153.3
CD83 molecule
chr1_-_153013588 3.04 ENST00000360379.3
small proline-rich protein 2D
chr11_+_60223225 2.99 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr11_-_47870091 2.97 ENST00000526870.1
nucleoporin 160kDa
chr2_+_79252834 2.93 ENST00000409471.1
regenerating islet-derived 3 gamma
chr22_+_21128167 2.93 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr17_+_7462103 2.90 ENST00000396545.4
tumor necrosis factor (ligand) superfamily, member 13
chr13_+_31309645 2.89 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chrX_+_151883090 2.87 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
melanoma antigen family A, 2B
chr19_-_51537982 2.86 ENST00000525263.1
kallikrein-related peptidase 12
chr17_+_7461849 2.82 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_90192768 2.81 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr15_+_89631647 2.81 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chr19_+_52901094 2.81 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
zinc finger protein 528
chr19_-_51538148 2.78 ENST00000319590.4
ENST00000250351.4
kallikrein-related peptidase 12
chr3_+_121796697 2.76 ENST00000482356.1
ENST00000393627.2
CD86 molecule
chr9_-_116837249 2.73 ENST00000466610.2
alpha-1-microglobulin/bikunin precursor
chr17_+_7461781 2.72 ENST00000349228.4
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_79252822 2.70 ENST00000272324.5
regenerating islet-derived 3 gamma
chr2_-_152590946 2.63 ENST00000172853.10
nebulin
chr2_-_79386786 2.60 ENST00000393878.1
ENST00000305165.2
ENST00000409839.3
regenerating islet-derived 3 alpha
chr2_+_79252804 2.58 ENST00000393897.2
regenerating islet-derived 3 gamma
chr2_-_152590982 2.52 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
nebulin
chr17_+_7462031 2.52 ENST00000380535.4
tumor necrosis factor (ligand) superfamily, member 13
chr8_-_21771182 2.46 ENST00000523932.1
ENST00000544659.1
docking protein 2, 56kDa
chr11_-_62457371 2.41 ENST00000317449.4
LRRN4 C-terminal like
chr1_-_119683251 2.36 ENST00000369426.5
ENST00000235521.4
tryptophanyl tRNA synthetase 2, mitochondrial
chr13_-_95131923 2.34 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr17_-_44657017 2.33 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ADP-ribosylation factor-like 17A
chr9_+_124048864 2.28 ENST00000545652.1
gelsolin
chr19_-_40228657 2.24 ENST00000221804.4
Charcot-Leyden crystal galectin
chr3_-_49158218 2.20 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
ubiquitin specific peptidase 19
chr3_+_125694347 2.19 ENST00000505382.1
ENST00000511082.1
rhophilin associated tail protein 1B
chr1_-_119682812 2.13 ENST00000537870.1
tryptophanyl tRNA synthetase 2, mitochondrial
chr19_+_17337473 2.13 ENST00000598068.1
occludin/ELL domain containing 1
chr1_+_171227069 2.07 ENST00000354841.4
flavin containing monooxygenase 1
chr11_+_9482551 2.02 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
zinc finger protein 143
chr17_+_7461613 2.01 ENST00000438470.1
ENST00000436057.1
tumor necrosis factor (ligand) superfamily, member 13
chr6_-_32784687 1.98 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr1_+_13359819 1.94 ENST00000376168.1
PRAME family member 5
chr14_+_22458631 1.94 ENST00000390444.1
T cell receptor alpha variable 16
chr19_-_7766991 1.93 ENST00000597921.1
ENST00000346664.5
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr3_-_49158312 1.92 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
ubiquitin specific peptidase 19
chr3_+_186435065 1.90 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr2_-_37193606 1.86 ENST00000379213.2
ENST00000263918.4
striatin, calmodulin binding protein
chr17_+_67410832 1.83 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chrX_-_71458802 1.81 ENST00000373657.1
ENST00000334463.3
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr4_+_69681710 1.80 ENST00000265403.7
ENST00000458688.2
UDP glucuronosyltransferase 2 family, polypeptide B10
chr17_-_44439084 1.79 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ADP-ribosylation factor-like 17B
chr11_+_9482512 1.78 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
zinc finger protein 143
chr13_+_51483814 1.77 ENST00000336617.3
ENST00000422660.1
ribonuclease H2, subunit B
chr12_+_133757995 1.75 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
zinc finger protein 268
chr4_-_80329356 1.75 ENST00000358842.3
glycerol kinase 2
chr3_+_190105909 1.73 ENST00000456423.1
claudin 16
chr1_+_15943995 1.72 ENST00000480945.1
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr17_+_7461580 1.72 ENST00000483039.1
ENST00000396542.1
tumor necrosis factor (ligand) superfamily, member 13
chr15_+_89631381 1.70 ENST00000352732.5
abhydrolase domain containing 2
chr16_-_20367584 1.70 ENST00000570689.1
uromodulin
chr6_+_135502408 1.70 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr15_-_38519066 1.69 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
chr12_-_9360966 1.64 ENST00000261336.2
pregnancy-zone protein
chr6_-_82462425 1.63 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
family with sequence similarity 46, member A
chr9_+_27109392 1.59 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr1_+_100818156 1.57 ENST00000336454.3
cell division cycle 14A
chr11_+_7626950 1.55 ENST00000530181.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_104905840 1.52 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr12_+_57828521 1.52 ENST00000309668.2
inhibin, beta C
chr6_+_135502501 1.51 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr1_+_160709029 1.48 ENST00000444090.2
ENST00000441662.2
SLAM family member 7
chr8_-_20040638 1.47 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr6_+_135502466 1.47 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr4_+_118955500 1.47 ENST00000296499.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_-_70361579 1.46 ENST00000512583.1
UDP glucuronosyltransferase 2 family, polypeptide B4
chr12_-_110883346 1.45 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr17_-_33760269 1.41 ENST00000452764.3
schlafen family member 12
chr10_+_35484793 1.41 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr1_+_40915725 1.41 ENST00000484445.1
ENST00000411995.2
ENST00000361584.3
ZFP69 zinc finger protein B
chr19_+_54704610 1.40 ENST00000302907.4
ribosomal protein S9
chr15_-_35088340 1.39 ENST00000290378.4
actin, alpha, cardiac muscle 1
chr4_-_70361615 1.37 ENST00000305107.6
UDP glucuronosyltransferase 2 family, polypeptide B4
chr7_+_95115210 1.37 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr16_+_2083265 1.35 ENST00000565855.1
ENST00000566198.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr10_+_96443378 1.34 ENST00000285979.6
cytochrome P450, family 2, subfamily C, polypeptide 18
chr7_+_107384142 1.27 ENST00000440859.3
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr19_-_51487282 1.27 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
kallikrein-related peptidase 7
chr19_-_44860820 1.27 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
zinc finger protein 112
chr19_+_54704718 1.26 ENST00000391752.1
ENST00000402367.1
ENST00000391751.3
ribosomal protein S9
chr12_-_53074182 1.23 ENST00000252244.3
keratin 1
chr16_+_33006369 1.21 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr4_-_46911223 1.21 ENST00000396533.1
cytochrome c oxidase subunit VIIb2
chr10_-_104597286 1.20 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr6_+_161123270 1.20 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
plasminogen
chr11_+_64323156 1.19 ENST00000377585.3
solute carrier family 22 (organic anion/urate transporter), member 11
chr6_+_43266063 1.16 ENST00000372574.3
solute carrier family 22 (organic anion transporter), member 7
chr3_-_150264272 1.16 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
stress-associated endoplasmic reticulum protein 1
chr3_+_186435137 1.13 ENST00000447445.1
kininogen 1
chr6_+_72922505 1.12 ENST00000401910.3
regulating synaptic membrane exocytosis 1
chr21_-_35883541 1.11 ENST00000399284.1
potassium voltage-gated channel, Isk-related family, member 1
chr1_-_186649543 1.11 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr22_+_38082330 1.11 ENST00000359114.4
nucleolar protein 12
chr5_+_43603229 1.11 ENST00000344920.4
ENST00000512996.2
nicotinamide nucleotide transhydrogenase
chr6_+_72926145 1.10 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr8_+_31496809 1.09 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr8_-_13372253 1.08 ENST00000316609.5
deleted in liver cancer 1
chr1_+_182419261 1.07 ENST00000294854.8
ENST00000542961.1
regulator of G-protein signaling like 1
chr11_-_47870019 1.07 ENST00000378460.2
nucleoporin 160kDa
chr11_-_47869865 1.07 ENST00000530326.1
ENST00000532747.1
nucleoporin 160kDa
chr20_-_3762087 1.07 ENST00000379756.3
sperm flagellar 1
chr11_+_113185292 1.05 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
tetratricopeptide repeat domain 12
chr19_-_54804173 1.04 ENST00000391744.3
ENST00000251390.3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr8_+_27168988 1.02 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr6_+_43739697 0.98 ENST00000230480.6
vascular endothelial growth factor A
chr19_+_18794470 0.98 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr6_+_72922590 0.95 ENST00000523963.1
regulating synaptic membrane exocytosis 1
chr17_-_73505961 0.93 ENST00000433559.2
CASK interacting protein 2
chr2_-_128615681 0.93 ENST00000409955.1
ENST00000272645.4
polymerase (RNA) II (DNA directed) polypeptide D
chr14_+_22446680 0.93 ENST00000390443.3
T cell receptor alpha variable 8-6
chr12_-_89919965 0.92 ENST00000548729.1
POC1B-GALNT4 readthrough
chr7_+_7606497 0.91 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
missing oocyte, meiosis regulator, homolog (Drosophila)
chr1_-_173176452 0.91 ENST00000281834.3
tumor necrosis factor (ligand) superfamily, member 4
chr2_+_191334212 0.91 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr1_-_153514241 0.89 ENST00000368718.1
ENST00000359215.1
S100 calcium binding protein A5
chr22_+_22730353 0.87 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr7_+_149535455 0.86 ENST00000223210.4
ENST00000460379.1
zinc finger protein 862
chr15_+_67420441 0.86 ENST00000558894.1
SMAD family member 3
chr17_-_27278304 0.85 ENST00000577226.1
PHD finger protein 12
chr4_-_75695366 0.83 ENST00000512743.1
betacellulin
chr18_-_29264467 0.82 ENST00000383131.3
ENST00000237019.7
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr12_+_26348582 0.82 ENST00000535504.1
sarcospan
chr12_-_86650077 0.79 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_171283331 0.78 ENST00000367749.3
flavin containing monooxygenase 4
chr9_+_27109133 0.77 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr4_+_75230853 0.75 ENST00000244869.2
epiregulin
chr12_-_86650045 0.75 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr17_-_3499125 0.73 ENST00000399759.3
transient receptor potential cation channel, subfamily V, member 1
chr12_+_122516626 0.73 ENST00000319080.7
MLX interacting protein
chr9_+_111624577 0.72 ENST00000333999.3
actin-like 7A
chr7_+_143657027 0.72 ENST00000392899.1
olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
chr1_-_169703203 0.72 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr4_-_168155169 0.70 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_+_113185251 0.69 ENST00000529221.1
tetratricopeptide repeat domain 12
chr12_+_7167980 0.69 ENST00000360817.5
ENST00000402681.3
complement component 1, s subcomponent
chr2_+_185463093 0.68 ENST00000302277.6
zinc finger protein 804A
chr19_-_7812397 0.66 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209 molecule
chr7_-_99277610 0.65 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr1_-_222763240 0.65 ENST00000352967.4
ENST00000391882.1
ENST00000543857.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr18_-_29264669 0.62 ENST00000306851.5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr4_-_16077741 0.62 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
prominin 1
chrX_+_99839799 0.61 ENST00000373031.4
tenomodulin
chr17_-_34257731 0.59 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RAD52 motif 1
chr3_-_178969403 0.58 ENST00000314235.5
ENST00000392685.2
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_+_167704838 0.57 ENST00000366829.2
unc-93 homolog A (C. elegans)
chr12_-_10251576 0.56 ENST00000315330.4
C-type lectin domain family 1, member A
chr17_-_39646116 0.53 ENST00000328119.6
keratin 36
chr2_-_87248975 0.53 ENST00000409310.2
ENST00000355705.3
plasminogen-like B1
chr7_-_137686791 0.51 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr12_-_10251603 0.50 ENST00000457018.2
C-type lectin domain family 1, member A
chr3_-_8811288 0.49 ENST00000316793.3
ENST00000431493.1
oxytocin receptor
chr4_-_69536346 0.48 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr13_+_49684445 0.48 ENST00000398316.3
fibronectin type III domain containing 3A
chr7_-_112430647 0.47 ENST00000312814.6
transmembrane protein 168

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.6 4.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.5 4.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.3 5.2 GO:0007525 somatic muscle development(GO:0007525)
1.2 14.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.1 3.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.1 3.4 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
1.0 7.1 GO:0048241 epinephrine transport(GO:0048241)
0.9 2.8 GO:0006711 estrogen catabolic process(GO:0006711)
0.9 6.5 GO:0008218 bioluminescence(GO:0008218)
0.9 2.8 GO:0032641 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.9 4.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.8 5.0 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.8 7.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 6.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.7 3.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.7 3.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.7 2.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.7 3.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.6 1.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 1.8 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.6 3.5 GO:0010193 response to ozone(GO:0010193)
0.6 3.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.5 10.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.5 11.1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.5 2.3 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4 2.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.4 1.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.4 4.3 GO:0042940 D-amino acid transport(GO:0042940)
0.4 1.2 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 1.9 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 3.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 1.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 2.2 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.4 1.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.7 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.3 1.0 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.3 2.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 2.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.3 1.0 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 2.9 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 4.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.3 0.9 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 2.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 1.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 2.1 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.8 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.2 1.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 0.7 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.2 1.1 GO:0006740 NADPH regeneration(GO:0006740)
0.2 1.3 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 1.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 3.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 0.9 GO:0046968 peptide antigen transport(GO:0046968)
0.2 2.7 GO:0018298 porphyrin-containing compound catabolic process(GO:0006787) protein-chromophore linkage(GO:0018298) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 0.9 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.2 4.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.7 GO:0009822 alkaloid catabolic process(GO:0009822)
0.2 2.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.6 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2 0.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 5.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 10.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 3.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.2 GO:0015747 urate transport(GO:0015747)
0.1 1.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 3.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 18.4 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 12.9 GO:0070268 cornification(GO:0070268)
0.1 1.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 5.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 1.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 10.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.5 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.1 1.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.2 GO:0006702 androgen biosynthetic process(GO:0006702)
0.1 1.1 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 5.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 5.1 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.8 GO:0042737 drug catabolic process(GO:0042737)
0.1 1.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.8 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 1.3 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 4.2 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 1.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 1.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 5.6 GO:0050900 leukocyte migration(GO:0050900)
0.0 1.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3 4.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 5.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 1.5 GO:0097179 protease inhibitor complex(GO:0097179)
0.3 3.5 GO:0043203 axon hillock(GO:0043203)
0.3 1.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 9.8 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.6 GO:0060091 kinocilium(GO:0060091)
0.2 1.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 3.4 GO:0042588 zymogen granule(GO:0042588)
0.2 1.5 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.2 8.4 GO:0002102 podosome(GO:0002102)
0.1 2.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 5.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 10.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 18.4 GO:0072562 blood microparticle(GO:0072562)
0.1 2.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 3.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 12.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 17.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.5 GO:0001533 cornified envelope(GO:0001533)
0.1 3.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.3 GO:0035579 specific granule membrane(GO:0035579)
0.1 2.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 13.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.2 GO:0005901 caveola(GO:0005901)
0.0 2.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 4.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 2.9 GO:0030018 Z disc(GO:0030018)
0.0 3.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 31.1 GO:0005615 extracellular space(GO:0005615)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 15.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.6 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.8 7.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.1 3.4 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
1.0 2.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.9 11.1 GO:0089720 caspase binding(GO:0089720)
0.9 4.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.8 8.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.7 5.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.7 2.7 GO:0019862 IgA binding(GO:0019862)
0.7 12.1 GO:0019864 IgG binding(GO:0019864)
0.6 5.7 GO:0031433 telethonin binding(GO:0031433)
0.5 1.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.5 5.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.4 4.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 4.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.4 2.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.3 4.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 2.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 15.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 2.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.1 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 1.9 GO:0019863 IgE binding(GO:0019863)
0.3 4.8 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 12.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 4.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 2.3 GO:0045159 myosin II binding(GO:0045159)
0.2 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.2 GO:1990405 protein antigen binding(GO:1990405)
0.1 25.9 GO:0003823 antigen binding(GO:0003823)
0.1 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 5.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 5.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 2.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 10.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 11.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 2.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.7 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 2.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 10.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 3.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 3.4 GO:0005518 collagen binding(GO:0005518)
0.0 10.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 2.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 1.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 3.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0042805 actinin binding(GO:0042805)
0.0 7.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.1 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 16.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 18.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.3 ST GAQ PATHWAY G alpha q Pathway
0.1 3.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 3.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 9.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 4.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 17.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 12.2 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 5.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 10.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 5.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 4.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.2 3.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 4.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 10.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 3.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 5.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 14.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 3.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 5.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 6.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 3.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 7.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling