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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for POU3F2

Z-value: 1.07

Motif logo

Transcription factors associated with POU3F2

Gene Symbol Gene ID Gene Info
ENSG00000184486.7 POU class 3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v2_chr6_+_99282570_99282591-0.407.9e-10Click!

Activity profile of POU3F2 motif

Sorted Z-values of POU3F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_8102714 43.59 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr5_+_159848807 43.07 ENST00000352433.5
pituitary tumor-transforming 1
chr3_-_81811312 39.32 ENST00000429644.2
glucan (1,4-alpha-), branching enzyme 1
chr5_+_159848854 38.77 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr8_+_132952112 37.23 ENST00000520362.1
ENST00000519656.1
EFR3 homolog A (S. cerevisiae)
chr15_+_65822756 34.54 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
protein tyrosine phosphatase-like A domain containing 1
chr9_+_75766652 30.89 ENST00000257497.6
annexin A1
chr2_+_201936707 30.89 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr5_+_68530668 27.00 ENST00000506563.1
cyclin-dependent kinase 7
chr2_-_169769787 25.64 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr3_+_180630090 24.29 ENST00000357559.4
ENST00000305586.7
fragile X mental retardation, autosomal homolog 1
chr1_+_165864821 23.72 ENST00000470820.1
uridine-cytidine kinase 2
chr15_-_63448973 23.08 ENST00000462430.1
ribosomal protein S27-like
chr1_+_165864800 22.85 ENST00000469256.2
uridine-cytidine kinase 2
chr1_-_197115818 22.57 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr4_-_47465666 21.76 ENST00000381571.4
COMM domain containing 8
chr14_+_97263641 21.25 ENST00000216639.3
vaccinia related kinase 1
chr5_+_68530697 20.42 ENST00000256443.3
ENST00000514676.1
cyclin-dependent kinase 7
chr2_+_198380763 20.11 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr15_-_56209306 20.10 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr4_+_88896819 19.65 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr9_+_42671887 19.19 ENST00000456520.1
ENST00000377391.3
COBW domain containing 7
chr3_-_149095652 18.99 ENST00000305366.3
transmembrane 4 L six family member 1
chr18_+_657578 18.80 ENST00000323274.10
thymidylate synthetase
chr13_+_34392185 18.75 ENST00000380071.3
replication factor C (activator 1) 3, 38kDa
chr12_+_69979210 18.68 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr4_-_170679024 18.58 ENST00000393381.2
chromosome 4 open reading frame 27
chr9_-_2844058 18.52 ENST00000397885.2
KIAA0020
chr16_-_46655538 18.31 ENST00000303383.3
SHC SH2-domain binding protein 1
chr12_-_112847108 18.22 ENST00000549847.1
ribosomal protein L6
chr10_+_79793518 17.94 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr2_-_151344172 17.90 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr9_+_70856397 17.83 ENST00000360171.6
COBW domain containing 3
chr1_-_6420737 17.56 ENST00000541130.1
ENST00000377845.3
acyl-CoA thioesterase 7
chr21_-_33975547 16.98 ENST00000431599.1
chromosome 21 open reading frame 59
chr15_+_65823092 16.97 ENST00000566074.1
protein tyrosine phosphatase-like A domain containing 1
chr7_-_123197733 16.94 ENST00000470123.1
ENST00000471770.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr11_-_62609281 16.87 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr2_+_118572226 16.38 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr7_+_107531580 16.05 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
dihydrolipoamide dehydrogenase
chr11_+_20044600 15.99 ENST00000311043.8
neuron navigator 2
chr22_+_19467261 15.79 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
cell division cycle 45
chr13_+_48611665 15.71 ENST00000258662.2
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr12_-_6960407 15.69 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
cell division cycle associated 3
chr22_-_19466732 15.61 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr4_-_122744998 15.59 ENST00000274026.5
cyclin A2
chr1_+_53480598 15.49 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
sterol carrier protein 2
chr2_+_242289502 15.39 ENST00000451310.1
septin 2
chr13_+_98605902 15.26 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
importin 5
chr8_+_71485681 15.21 ENST00000391684.1
AC120194.1
chr14_+_56127989 14.92 ENST00000555573.1
kinectin 1 (kinesin receptor)
chrX_+_114827818 14.79 ENST00000420625.2
plastin 3
chr1_-_246357029 14.78 ENST00000391836.2
SET and MYND domain containing 3
chr11_-_33744487 14.69 ENST00000426650.2
CD59 molecule, complement regulatory protein
chr1_-_21377447 14.63 ENST00000374937.3
ENST00000264211.8
eukaryotic translation initiation factor 4 gamma, 3
chr10_+_62538089 14.61 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr2_+_122513109 14.51 ENST00000389682.3
ENST00000536142.1
translin
chr9_-_111775772 14.43 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
catenin (cadherin-associated protein), alpha-like 1
chr1_-_21377383 14.40 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr14_+_35747825 14.39 ENST00000540871.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr5_-_148929848 14.09 ENST00000504676.1
ENST00000515435.1
casein kinase 1, alpha 1
chr22_-_19466683 14.06 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
ubiquitin fusion degradation 1 like (yeast)
chr12_+_69080734 14.03 ENST00000378905.2
nucleoporin 107kDa
chr11_+_105948216 14.02 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr12_+_95867919 13.86 ENST00000261220.9
ENST00000549502.1
ENST00000553151.1
ENST00000550777.1
ENST00000551840.1
methionyl aminopeptidase 2
chr11_+_125496619 13.86 ENST00000532669.1
ENST00000278916.3
checkpoint kinase 1
chr3_-_64009658 13.69 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr1_+_203830703 13.65 ENST00000414487.2
small nuclear ribonucleoprotein polypeptide E
chr6_+_30689350 13.56 ENST00000330914.3
tubulin, beta class I
chr5_+_167913450 13.54 ENST00000231572.3
ENST00000538719.1
arginyl-tRNA synthetase
chr1_-_146040968 13.53 ENST00000401010.3
neuroblastoma breakpoint family, member 11
chr4_+_166248775 13.51 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
methylsterol monooxygenase 1
chr7_-_123198284 13.50 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr11_-_33743952 13.44 ENST00000534312.1
CD59 molecule, complement regulatory protein
chr6_-_5261141 13.44 ENST00000330636.4
ENST00000500576.2
LYR motif containing 4
chr6_-_53213780 13.34 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr1_-_145826450 13.32 ENST00000462900.2
G protein-coupled receptor 89A
chr11_-_33744256 13.27 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59 molecule, complement regulatory protein
chr11_-_47447767 13.23 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chrX_+_106871713 13.22 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
phosphoribosyl pyrophosphate synthetase 1
chr13_+_37581115 13.07 ENST00000481013.1
exosome component 8
chr18_+_657733 13.06 ENST00000323250.5
ENST00000323224.7
thymidylate synthetase
chr4_-_103746683 13.06 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr6_+_57037089 13.06 ENST00000370693.5
BCL2-associated athanogene 2
chr15_+_65843130 13.04 ENST00000569894.1
protein tyrosine phosphatase-like A domain containing 1
chr8_+_26150628 13.04 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr6_+_63921399 13.02 ENST00000356170.3
FK506 binding protein 1C
chr7_-_121036337 12.95 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
family with sequence similarity 3, member C
chr10_+_62538248 12.95 ENST00000448257.2
cyclin-dependent kinase 1
chr3_-_194188956 12.84 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr6_+_30689401 12.83 ENST00000396389.1
ENST00000396384.1
tubulin, beta class I
chr5_+_72143988 12.83 ENST00000506351.2
transportin 1
chr9_+_36572851 12.82 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
maternal embryonic leucine zipper kinase
chr19_+_22469210 12.82 ENST00000601693.1
zinc finger protein 729
chr4_+_88343952 12.77 ENST00000440591.2
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr1_-_145827015 12.74 ENST00000534502.1
ENST00000313835.9
ENST00000454423.3
G protein-coupled receptor 89A
chr12_+_32832203 12.62 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr18_-_54305658 12.61 ENST00000586262.1
ENST00000217515.6
thioredoxin-like 1
chr7_+_56019486 12.61 ENST00000446692.1
ENST00000285298.4
ENST00000443449.1
glioblastoma amplified sequence
mitochondrial ribosomal protein S17
chr8_-_23261589 12.57 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr12_-_57146095 12.55 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr5_+_33440802 12.53 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr7_-_87856280 12.52 ENST00000490437.1
ENST00000431660.1
sorcin
chrX_+_11129388 12.34 ENST00000321143.4
ENST00000380763.3
ENST00000380762.4
holocytochrome c synthase
chr2_-_74619152 12.33 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr7_-_87856303 12.32 ENST00000394641.3
sorcin
chr12_+_19358228 12.31 ENST00000424268.1
ENST00000543806.1
pleckstrin homology domain containing, family A member 5
chr1_-_95391315 12.24 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr11_-_122931881 12.21 ENST00000526110.1
ENST00000227378.3
heat shock 70kDa protein 8
chr14_+_53173910 12.19 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr8_+_48920960 12.19 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
ubiquitin-conjugating enzyme E2 variant 2
chr3_+_100053542 12.17 ENST00000394140.4
nitrilase family, member 2
chr4_+_57302297 12.16 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr18_+_9103957 12.09 ENST00000400033.1
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr12_-_30887948 12.02 ENST00000433722.2
caprin family member 2
chr3_-_127842612 11.93 ENST00000417360.1
ENST00000322623.5
RuvB-like AAA ATPase 1
chr1_-_200589859 11.91 ENST00000367350.4
kinesin family member 14
chr1_+_19578033 11.87 ENST00000330263.4
mRNA turnover 4 homolog (S. cerevisiae)
chr2_-_74618964 11.86 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr11_-_77348821 11.73 ENST00000528364.1
ENST00000532069.1
ENST00000525428.1
chloride channel, nucleotide-sensitive, 1A
chr8_+_104310661 11.69 ENST00000522566.1
frizzled family receptor 6
chr3_+_130569429 11.56 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr5_-_133510456 11.53 ENST00000520417.1
S-phase kinase-associated protein 1
chrX_-_152486108 11.50 ENST00000356661.5
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr12_-_32908809 11.43 ENST00000324868.8
tyrosyl-tRNA synthetase 2, mitochondrial
chr9_-_124922021 11.42 ENST00000537618.1
ENST00000373768.3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr7_+_135242652 11.39 ENST00000285968.6
ENST00000440390.2
nucleoporin 205kDa
chr12_+_27175476 11.37 ENST00000546323.1
ENST00000282892.3
mediator complex subunit 21
chr14_+_53173890 11.29 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr16_+_74330673 11.22 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr1_+_148560843 11.19 ENST00000442702.2
ENST00000369187.3
neuroblastoma breakpoint family, member 15
chr19_+_22469236 11.19 ENST00000357491.6
zinc finger protein 729
chr4_-_17513851 11.17 ENST00000281243.5
quinoid dihydropteridine reductase
chr16_+_81070792 11.17 ENST00000564241.1
ENST00000565237.1
ATM interactor
chr9_-_32573130 11.12 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr10_+_94352956 11.05 ENST00000260731.3
kinesin family member 11
chr2_-_209118974 11.03 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
isocitrate dehydrogenase 1 (NADP+), soluble
chr11_-_57298187 11.01 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr7_+_102988082 10.97 ENST00000292644.3
ENST00000544811.1
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr2_+_114195268 10.93 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
COBW domain containing 2
chr19_+_47634039 10.87 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr16_+_446713 10.87 ENST00000397722.1
ENST00000454619.1
NME/NM23 nucleoside diphosphate kinase 4
chrX_-_37706815 10.84 ENST00000378578.4
dynein, light chain, Tctex-type 3
chr8_-_81083341 10.84 ENST00000519303.2
tumor protein D52
chr13_+_53030107 10.80 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr15_-_77376269 10.77 ENST00000558745.1
tetraspanin 3
chr13_+_76123883 10.70 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr7_-_7679633 10.57 ENST00000401447.1
replication protein A3, 14kDa
chr12_-_10978957 10.57 ENST00000240619.2
taste receptor, type 2, member 10
chr5_-_43557791 10.56 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr11_+_85339623 10.55 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr4_+_57301896 10.53 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_-_47950745 10.51 ENST00000429422.1
microtubule-associated protein 4
chrX_-_77225135 10.48 ENST00000458128.1
phosphoglycerate mutase family member 4
chr16_-_69760409 10.46 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NAD(P)H dehydrogenase, quinone 1
chr2_-_33824382 10.35 ENST00000238823.8
family with sequence similarity 98, member A
chr20_+_30327063 10.34 ENST00000300403.6
ENST00000340513.4
TPX2, microtubule-associated
chr3_+_158288960 10.33 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
myeloid leukemia factor 1
chr8_-_101962777 10.33 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr17_-_8113542 10.24 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr7_-_148580563 10.19 ENST00000476773.1
enhancer of zeste homolog 2 (Drosophila)
chr4_-_103747011 10.18 ENST00000350435.7
ubiquitin-conjugating enzyme E2D 3
chr11_+_118889456 10.14 ENST00000528230.1
ENST00000525303.1
ENST00000434101.2
ENST00000359005.4
ENST00000533058.1
trafficking protein particle complex 4
chr1_-_153643442 10.05 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr11_+_125496400 10.03 ENST00000524737.1
checkpoint kinase 1
chr16_-_69373396 10.01 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
component of oligomeric golgi complex 8
chr11_+_17316870 9.95 ENST00000458064.2
nucleobindin 2
chr5_+_141346385 9.95 ENST00000513019.1
ENST00000356143.1
ring finger protein 14
chr7_-_32529973 9.92 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_37544209 9.89 ENST00000234179.2
protein kinase D3
chr7_-_64023441 9.85 ENST00000309683.6
zinc finger protein 680
chr4_-_56502426 9.82 ENST00000505262.1
ENST00000507338.1
neuromedin U
chr12_+_21207503 9.77 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr19_+_12917364 9.77 ENST00000221486.4
ribonuclease H2, subunit A
chr11_+_118889142 9.75 ENST00000533632.1
trafficking protein particle complex 4
chr9_-_21305312 9.75 ENST00000259555.4
interferon, alpha 5
chr13_-_48575401 9.73 ENST00000433022.1
ENST00000544100.1
succinate-CoA ligase, ADP-forming, beta subunit
chr19_+_13049413 9.73 ENST00000316448.5
ENST00000588454.1
calreticulin
chr2_+_109204909 9.65 ENST00000393310.1
LIM and senescent cell antigen-like domains 1
chr13_-_31038370 9.65 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr4_-_56502451 9.62 ENST00000511469.1
ENST00000264218.3
neuromedin U
chr14_-_20801427 9.60 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr11_-_102668879 9.56 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr11_-_14380664 9.54 ENST00000545643.1
ENST00000256196.4
related RAS viral (r-ras) oncogene homolog 2
chr22_+_39077947 9.49 ENST00000216034.4
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr2_+_216176761 9.48 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr9_-_70488865 9.48 ENST00000377392.5
COBW domain containing 5
chr5_+_32531893 9.48 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_-_110283138 9.46 ENST00000256594.3
glutathione S-transferase mu 3 (brain)
chr1_-_193029192 9.46 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr1_-_193028426 9.45 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
ubiquitin carboxyl-terminal hydrolase L5
chr11_+_60609537 9.44 ENST00000227520.5
coiled-coil domain containing 86
chr3_-_64009102 9.43 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr5_+_34915444 9.43 ENST00000336767.5
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr8_-_90996837 9.39 ENST00000519426.1
ENST00000265433.3
nibrin
chr10_-_58120996 9.39 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZW10 interacting kinetochore protein
chr12_+_118454500 9.39 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
replication factor C (activator 1) 5, 36.5kDa
chr6_-_131291572 9.36 ENST00000529208.1
erythrocyte membrane protein band 4.1-like 2
chr11_+_62529008 9.36 ENST00000301788.7
ENST00000533442.1
polymerase (RNA) II (DNA directed) polypeptide G
chr1_+_46769303 9.36 ENST00000311672.5
ubiquinol-cytochrome c reductase hinge protein

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 46.6 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
10.3 41.4 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
10.3 30.9 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
8.3 24.8 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
8.0 31.9 GO:0019860 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
7.6 22.7 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
6.3 18.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
6.2 18.7 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
6.2 49.4 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
6.1 48.8 GO:0090166 Golgi disassembly(GO:0090166)
5.9 5.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
5.6 28.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
5.5 5.5 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
5.4 16.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.3 16.0 GO:0006097 glyoxylate cycle(GO:0006097)
5.3 15.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
5.2 15.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
4.7 18.9 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
4.7 18.8 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
4.5 13.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
4.5 13.5 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
4.4 17.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
4.4 21.8 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
4.2 12.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
4.2 20.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
4.2 4.2 GO:0043921 modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
4.0 40.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
4.0 16.0 GO:0021564 vagus nerve development(GO:0021564)
4.0 23.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
3.9 15.6 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
3.8 22.8 GO:0051661 maintenance of centrosome location(GO:0051661)
3.7 18.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
3.5 24.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.4 10.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
3.4 17.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
3.4 10.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
3.4 10.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
3.3 13.4 GO:0009106 lipoate metabolic process(GO:0009106)
3.3 13.2 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
3.2 22.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
3.1 6.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
3.1 12.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
3.1 9.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
3.1 9.3 GO:0006597 spermine biosynthetic process(GO:0006597)
3.0 24.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
3.0 53.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
3.0 9.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
3.0 5.9 GO:0031627 telomeric loop formation(GO:0031627)
2.9 11.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.8 5.7 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.8 8.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
2.8 5.5 GO:1990535 neuron projection maintenance(GO:1990535)
2.7 13.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
2.7 5.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.7 8.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
2.7 8.0 GO:1990523 bone regeneration(GO:1990523)
2.6 10.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.6 10.4 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
2.6 7.8 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
2.6 10.3 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
2.6 23.0 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
2.6 12.8 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
2.6 17.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
2.5 12.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
2.5 20.0 GO:2000252 negative regulation of feeding behavior(GO:2000252)
2.5 12.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
2.4 12.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
2.4 7.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
2.4 9.6 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
2.4 4.8 GO:1904430 negative regulation of t-circle formation(GO:1904430)
2.3 18.6 GO:0006528 asparagine metabolic process(GO:0006528)
2.3 9.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
2.3 57.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
2.3 13.7 GO:0051012 microtubule sliding(GO:0051012)
2.3 11.4 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
2.3 2.3 GO:1904868 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
2.3 13.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
2.2 13.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
2.2 6.7 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
2.2 97.5 GO:0045143 homologous chromosome segregation(GO:0045143)
2.2 8.8 GO:0097325 melanocyte proliferation(GO:0097325)
2.2 6.6 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
2.2 8.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
2.2 6.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.2 6.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
2.1 12.8 GO:0031126 snoRNA 3'-end processing(GO:0031126)
2.1 6.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
2.1 10.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
2.1 10.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
2.1 8.5 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
2.1 31.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.0 22.5 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.0 18.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.0 12.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.0 6.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
2.0 6.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.0 8.0 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
2.0 5.9 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
2.0 13.7 GO:0070294 renal sodium ion absorption(GO:0070294)
2.0 29.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
2.0 3.9 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
1.9 5.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.9 5.8 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.9 15.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.9 7.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
1.9 3.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.8 12.5 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
1.8 8.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
1.7 6.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.7 15.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
1.7 81.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
1.7 5.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.7 1.7 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
1.7 5.0 GO:0002188 translation reinitiation(GO:0002188)
1.7 125.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.7 20.1 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.7 5.0 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.6 1.6 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
1.6 80.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.6 6.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.6 8.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
1.6 9.7 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
1.6 21.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.6 21.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
1.6 6.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
1.6 11.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.6 15.7 GO:0042262 DNA protection(GO:0042262)
1.5 19.9 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.5 18.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.5 6.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
1.5 4.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.5 9.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
1.5 4.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
1.5 5.8 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
1.5 2.9 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.5 5.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
1.5 5.8 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.4 12.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
1.4 4.2 GO:1904647 response to rotenone(GO:1904647)
1.4 5.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.4 9.8 GO:0089700 protein kinase D signaling(GO:0089700)
1.4 26.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.4 2.8 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
1.4 8.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
1.4 5.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.4 2.8 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.4 6.9 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
1.3 16.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.3 14.6 GO:0001778 plasma membrane repair(GO:0001778)
1.3 2.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.3 3.9 GO:1900063 regulation of peroxisome organization(GO:1900063)
1.3 13.1 GO:0015939 pantothenate metabolic process(GO:0015939)
1.3 1.3 GO:0006789 bilirubin conjugation(GO:0006789)
1.2 8.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.2 6.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.2 3.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.2 8.3 GO:0009597 detection of virus(GO:0009597)
1.2 3.5 GO:0061317 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
1.2 22.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.2 16.5 GO:0021670 lateral ventricle development(GO:0021670)
1.2 16.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
1.2 13.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
1.1 8.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.1 5.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.1 5.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.1 11.2 GO:0042373 vitamin K metabolic process(GO:0042373)
1.1 7.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.1 25.5 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
1.1 3.3 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.1 111.9 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
1.1 2.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
1.1 9.7 GO:0010265 SCF complex assembly(GO:0010265)
1.1 6.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.1 4.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
1.1 46.4 GO:0006378 mRNA polyadenylation(GO:0006378)
1.1 8.6 GO:0007144 female meiosis I(GO:0007144)
1.1 3.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.0 10.5 GO:0000733 DNA strand renaturation(GO:0000733)
1.0 5.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.0 7.1 GO:0008218 bioluminescence(GO:0008218)
1.0 10.2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
1.0 3.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.0 6.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.0 8.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
1.0 9.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
1.0 1.0 GO:0051030 snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030)
1.0 3.0 GO:0010506 regulation of autophagy(GO:0010506)
1.0 7.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
1.0 11.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
1.0 5.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 13.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.9 18.0 GO:0000729 DNA double-strand break processing(GO:0000729)
0.9 35.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.9 2.8 GO:1900133 positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568)
0.9 24.3 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.9 10.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.9 11.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.9 5.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.9 5.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.9 2.7 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.9 2.7 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.9 16.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.9 4.4 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.9 6.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.9 4.3 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.9 5.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.9 2.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.8 2.5 GO:0036071 N-glycan fucosylation(GO:0036071)
0.8 37.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.8 5.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 3.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.8 12.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.8 17.2 GO:0051764 actin crosslink formation(GO:0051764)
0.8 6.5 GO:0015846 polyamine transport(GO:0015846)
0.8 3.3 GO:0051013 microtubule severing(GO:0051013)
0.8 10.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.8 2.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.8 0.8 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.8 10.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.8 15.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.8 1.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.8 2.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.8 0.8 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.8 2.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.8 2.3 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.8 8.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.8 3.8 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.7 4.5 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.7 25.3 GO:0090383 phagosome acidification(GO:0090383)
0.7 11.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.7 3.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.7 8.0 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.7 4.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.7 3.6 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.7 6.5 GO:0070986 left/right axis specification(GO:0070986)
0.7 3.6 GO:0035617 stress granule disassembly(GO:0035617)
0.7 10.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 1.4 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.7 4.3 GO:0032328 alanine transport(GO:0032328)
0.7 2.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.7 2.8 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.7 5.5 GO:0015866 ADP transport(GO:0015866)
0.7 2.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.7 8.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.7 5.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 22.4 GO:0051452 intracellular pH reduction(GO:0051452)
0.7 28.9 GO:0007052 mitotic spindle organization(GO:0007052)
0.7 2.0 GO:0034227 tRNA thio-modification(GO:0034227)
0.7 4.0 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.7 44.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.7 6.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.7 11.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.7 2.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.7 2.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.7 15.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.6 4.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.6 30.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.6 1.9 GO:0051305 meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305)
0.6 3.8 GO:0034214 protein hexamerization(GO:0034214)
0.6 3.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.6 2.5 GO:0006868 glutamine transport(GO:0006868) glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.6 0.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.6 1.9 GO:0010040 response to iron(II) ion(GO:0010040)
0.6 4.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.6 6.7 GO:0051451 myoblast migration(GO:0051451)
0.6 4.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.6 6.1 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.6 43.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 17.6 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.6 54.6 GO:0051225 spindle assembly(GO:0051225)
0.6 34.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.6 17.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.6 7.3 GO:0061458 reproductive system development(GO:0061458)
0.6 11.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.5 3.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.5 16.3 GO:0014904 myotube cell development(GO:0014904)
0.5 4.8 GO:0007143 female meiotic division(GO:0007143)
0.5 22.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.5 8.0 GO:0018345 protein palmitoylation(GO:0018345)
0.5 2.1 GO:0060455 positive regulation of norepinephrine secretion(GO:0010701) negative regulation of gastric acid secretion(GO:0060455)
0.5 9.4 GO:0008228 opsonization(GO:0008228)
0.5 25.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.5 19.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.5 5.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 8.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 12.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.5 9.0 GO:0017004 cytochrome complex assembly(GO:0017004)
0.5 2.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.5 1.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.5 6.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 10.4 GO:0003334 keratinocyte development(GO:0003334)
0.5 13.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 4.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.5 11.6 GO:0046688 response to copper ion(GO:0046688)
0.5 2.4 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.5 1.9 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 6.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5 5.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.5 3.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.4 3.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.4 8.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.4 3.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 23.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.4 1.6 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.4 2.8 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.4 2.0 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) blood vessel endothelial cell fate specification(GO:0097101) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 2.4 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.4 0.4 GO:0007135 meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144)
0.4 17.6 GO:0075733 intracellular transport of virus(GO:0075733) multi-organism intracellular transport(GO:1902583)
0.4 4.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.4 1.1 GO:0042254 ribosome biogenesis(GO:0042254)
0.4 4.9 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.4 1.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.4 2.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.4 1.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 29.3 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 3.2 GO:0001783 B cell apoptotic process(GO:0001783)
0.4 11.2 GO:0006301 postreplication repair(GO:0006301)
0.4 2.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 3.5 GO:0031053 primary miRNA processing(GO:0031053)
0.3 10.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.3 1.0 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.3 3.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 2.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 2.0 GO:0071383 cellular response to steroid hormone stimulus(GO:0071383)
0.3 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 4.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.3 5.8 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.3 1.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 2.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.3 0.9 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.3 8.8 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.3 3.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3 8.7 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.3 2.5 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 0.9 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 7.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 1.8 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.3 4.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 6.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.3 1.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.3 15.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.3 12.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 0.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3 9.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.3 17.7 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.3 0.3 GO:0045851 pH reduction(GO:0045851)
0.3 22.2 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.3 3.8 GO:0014820 tonic smooth muscle contraction(GO:0014820)
0.3 2.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.3 1.7 GO:0040016 embryonic cleavage(GO:0040016)
0.3 4.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.3 2.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.6 GO:0097050 type B pancreatic cell apoptotic process(GO:0097050) regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.3 4.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.3 1.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.3 1.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 5.2 GO:0006903 vesicle targeting(GO:0006903)
0.3 2.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 2.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 3.5 GO:0033622 integrin activation(GO:0033622)
0.2 10.1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 2.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.2 3.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.2 1.0 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.2 3.8 GO:0000338 protein deneddylation(GO:0000338)
0.2 5.6 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.2 1.1 GO:2001023 regulation of response to drug(GO:2001023)
0.2 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.2 16.4 GO:0016925 protein sumoylation(GO:0016925)
0.2 5.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.2 8.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 0.9 GO:0090045 positive regulation of deacetylase activity(GO:0090045)
0.2 1.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 1.3 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.2 3.6 GO:0007586 digestion(GO:0007586)
0.2 0.9 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.2 1.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 3.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 12.0 GO:0031529 ruffle organization(GO:0031529)
0.2 11.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 1.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.2 1.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 0.9 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.2 1.9 GO:0097264 self proteolysis(GO:0097264)
0.2 4.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.2 2.3 GO:0008356 asymmetric cell division(GO:0008356)
0.2 0.8 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 2.5 GO:0015884 folic acid transport(GO:0015884)
0.2 5.1 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 2.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 1.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 3.5 GO:0016540 protein autoprocessing(GO:0016540)
0.2 5.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 8.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.2 1.3 GO:0021894 cerebral cortex GABAergic interneuron differentiation(GO:0021892) cerebral cortex GABAergic interneuron development(GO:0021894)
0.2 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.2 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 7.0 GO:0051983 regulation of chromosome segregation(GO:0051983)
0.2 2.7 GO:0030183 B cell differentiation(GO:0030183)
0.2 1.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2 12.7 GO:0045333 cellular respiration(GO:0045333)
0.2 4.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 7.9 GO:0034644 cellular response to UV(GO:0034644)
0.2 2.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.5 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.2 3.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.2 20.8 GO:0090002 establishment of protein localization to plasma membrane(GO:0090002)
0.2 3.4 GO:0071356 cellular response to tumor necrosis factor(GO:0071356)
0.2 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 5.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.2 8.6 GO:0021766 hippocampus development(GO:0021766)
0.1 2.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 4.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0070997 neuron death(GO:0070997)
0.1 3.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.9 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 11.5 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1 1.9 GO:0018126 protein hydroxylation(GO:0018126)
0.1 2.3 GO:0043486 histone exchange(GO:0043486)
0.1 8.6 GO:0006338 chromatin remodeling(GO:0006338)
0.1 2.9 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 1.0 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.1 1.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.4 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 2.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.6 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.1 1.4 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 0.5 GO:0035962 response to interleukin-13(GO:0035962)
0.1 1.7 GO:0043691 reverse cholesterol transport(GO:0043691)
0.1 8.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 3.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 2.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 3.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 1.0 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 1.0 GO:0001782 B cell homeostasis(GO:0001782)
0.1 1.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 3.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.7 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 1.8 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 4.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 2.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.4 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 1.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 2.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.4 GO:0033189 response to vitamin A(GO:0033189)
0.1 7.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.5 GO:0006552 leucine metabolic process(GO:0006551) leucine catabolic process(GO:0006552)
0.1 0.5 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 16.7 GO:0051301 cell division(GO:0051301)
0.1 0.8 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 2.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 2.9 GO:0021549 cerebellum development(GO:0021549)
0.1 0.3 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 5.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 5.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.3 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 2.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 2.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.9 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 3.3 GO:0006310 DNA recombination(GO:0006310)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.2 GO:0007498 mesoderm development(GO:0007498)
0.0 0.4 GO:0016071 mRNA metabolic process(GO:0016071)
0.0 0.4 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.6 GO:0032570 response to progesterone(GO:0032570)
0.0 0.7 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.6 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 3.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.4 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.1 GO:1902116 regulation of centriole replication(GO:0046599) negative regulation of organelle assembly(GO:1902116)
0.0 0.1 GO:0002855 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.1 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 47.4 GO:0070985 TFIIK complex(GO:0070985)
8.5 25.6 GO:0031262 Ndc80 complex(GO:0031262)
8.3 24.8 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
7.4 29.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
5.9 5.9 GO:0012506 vesicle membrane(GO:0012506)
5.8 46.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
5.5 27.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
5.2 15.6 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
5.1 30.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
4.8 14.5 GO:0043159 acrosomal matrix(GO:0043159)
4.7 28.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
4.7 9.3 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
4.6 55.5 GO:0031595 nuclear proteasome complex(GO:0031595)
4.5 13.5 GO:0005715 late recombination nodule(GO:0005715)
4.1 12.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
4.1 16.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
4.0 12.0 GO:0097447 dendritic tree(GO:0097447)
3.9 19.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
3.5 24.8 GO:0044326 dendritic spine neck(GO:0044326)
3.2 22.6 GO:0036449 microtubule minus-end(GO:0036449)
2.9 8.7 GO:0035370 UBC13-UEV1A complex(GO:0035370)
2.8 11.4 GO:0044611 nuclear pore inner ring(GO:0044611)
2.8 59.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
2.7 8.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.7 43.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
2.7 16.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.7 29.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
2.6 18.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.6 13.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
2.6 26.1 GO:1990023 mitotic spindle midzone(GO:1990023)
2.6 17.9 GO:0030870 Mre11 complex(GO:0030870)
2.4 43.2 GO:0005838 proteasome regulatory particle(GO:0005838)
2.4 18.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
2.4 2.4 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
2.2 8.6 GO:0031417 NatC complex(GO:0031417)
2.1 6.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.1 8.4 GO:1990246 uniplex complex(GO:1990246)
2.0 6.1 GO:0005588 collagen type V trimer(GO:0005588)
2.0 23.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.9 21.2 GO:0005614 interstitial matrix(GO:0005614)
1.9 22.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.9 7.6 GO:0030896 checkpoint clamp complex(GO:0030896)
1.9 9.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
1.9 5.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.8 5.4 GO:0034455 t-UTP complex(GO:0034455)
1.8 1.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
1.8 26.4 GO:0005641 nuclear envelope lumen(GO:0005641)
1.7 12.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
1.7 11.8 GO:0061617 MICOS complex(GO:0061617)
1.7 27.0 GO:0031080 nuclear pore outer ring(GO:0031080)
1.7 20.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.7 18.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.7 19.9 GO:0030008 TRAPP complex(GO:0030008)
1.6 24.2 GO:0005869 dynactin complex(GO:0005869)
1.6 8.1 GO:0032133 chromosome passenger complex(GO:0032133)
1.6 48.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.6 12.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
1.6 21.8 GO:0045120 pronucleus(GO:0045120)
1.5 18.0 GO:0017119 Golgi transport complex(GO:0017119)
1.5 10.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.5 8.7 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
1.4 18.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.4 86.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.4 9.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.4 16.9 GO:0051233 spindle midzone(GO:0051233)
1.4 8.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.4 6.9 GO:0097149 centralspindlin complex(GO:0097149)
1.4 15.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.4 19.3 GO:0097227 sperm annulus(GO:0097227)
1.4 15.0 GO:0035686 sperm fibrous sheath(GO:0035686)
1.3 8.0 GO:0070435 Shc-EGFR complex(GO:0070435)
1.3 43.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.3 28.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.3 6.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.3 11.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
1.3 10.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.2 4.9 GO:0061700 GATOR2 complex(GO:0061700)
1.2 20.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.2 6.1 GO:0032021 NELF complex(GO:0032021)
1.2 24.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.2 9.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.2 8.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.2 33.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.1 5.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.1 4.5 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
1.1 34.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.1 7.7 GO:0031298 replication fork protection complex(GO:0031298)
1.0 21.5 GO:0005839 proteasome core complex(GO:0005839)
1.0 11.1 GO:0071438 invadopodium membrane(GO:0071438)
1.0 15.7 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.0 9.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.0 5.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.0 9.6 GO:0016342 catenin complex(GO:0016342)
1.0 4.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.9 10.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.9 2.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.9 24.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.9 9.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.9 3.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.9 9.7 GO:0043203 axon hillock(GO:0043203)
0.9 15.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.9 6.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.9 14.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 2.5 GO:0030904 retromer complex(GO:0030904)
0.8 6.7 GO:0051286 cell tip(GO:0051286)
0.8 17.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.8 11.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.8 4.8 GO:0005688 U6 snRNP(GO:0005688)
0.8 14.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.8 2.4 GO:0031523 Myb complex(GO:0031523)
0.8 7.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.7 24.6 GO:0099738 cell cortex region(GO:0099738)
0.7 5.9 GO:0070187 telosome(GO:0070187)
0.7 12.1 GO:0097228 sperm principal piece(GO:0097228)
0.7 3.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.7 10.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.7 2.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.7 19.1 GO:0000502 proteasome complex(GO:0000502)
0.6 7.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.6 5.8 GO:0005916 fascia adherens(GO:0005916)
0.6 12.7 GO:0035861 site of double-strand break(GO:0035861)
0.6 6.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.6 11.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.6 32.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.6 1.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.6 24.4 GO:0043034 costamere(GO:0043034)
0.6 4.0 GO:0097209 epidermal lamellar body(GO:0097209)
0.6 21.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 39.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.6 4.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 1.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 2.7 GO:1990130 Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130)
0.5 4.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.5 2.2 GO:0031673 H zone(GO:0031673)
0.5 7.5 GO:0031209 SCAR complex(GO:0031209)
0.5 3.7 GO:0071203 WASH complex(GO:0071203)
0.5 6.2 GO:0005642 annulate lamellae(GO:0005642)
0.5 3.6 GO:0035253 ciliary rootlet(GO:0035253)
0.5 2.0 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.5 3.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 4.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 1.5 GO:0030314 junctional membrane complex(GO:0030314)
0.5 16.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 7.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.5 1.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.5 2.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.5 4.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 5.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.5 17.7 GO:0005876 spindle microtubule(GO:0005876)
0.4 22.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.4 1.3 GO:0031213 RSF complex(GO:0031213)
0.4 37.3 GO:0005643 nuclear pore(GO:0005643)
0.4 3.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.4 10.5 GO:0031143 pseudopodium(GO:0031143)
0.4 3.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.4 2.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 0.8 GO:0031906 late endosome lumen(GO:0031906)
0.4 6.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.4 6.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 32.0 GO:0000793 condensed chromosome(GO:0000793)
0.4 8.1 GO:0016580 Sin3 complex(GO:0016580)
0.4 4.6 GO:0005686 U2 snRNP(GO:0005686)
0.4 4.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 4.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.4 3.4 GO:0005915 zonula adherens(GO:0005915)
0.4 1.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 89.4 GO:0005819 spindle(GO:0005819)
0.4 1.1 GO:0097441 basilar dendrite(GO:0097441)
0.4 4.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 2.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.3 5.9 GO:0032433 filopodium tip(GO:0032433)
0.3 1.3 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.3 6.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 2.3 GO:0033269 internode region of axon(GO:0033269)
0.3 21.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 2.2 GO:0031415 NatA complex(GO:0031415)
0.3 5.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.3 2.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 11.2 GO:0005840 ribosome(GO:0005840)
0.3 15.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 26.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.3 0.9 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.3 11.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.3 2.1 GO:0016272 prefoldin complex(GO:0016272)
0.3 15.5 GO:0001772 immunological synapse(GO:0001772)
0.3 1.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.3 25.7 GO:0005604 basement membrane(GO:0005604)
0.3 23.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 13.3 GO:0016235 aggresome(GO:0016235)
0.3 1.8 GO:0005955 calcineurin complex(GO:0005955)
0.3 9.7 GO:0016592 mediator complex(GO:0016592)
0.3 3.1 GO:0060077 inhibitory synapse(GO:0060077)
0.3 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.3 2.3 GO:0097470 ribbon synapse(GO:0097470)
0.2 2.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 3.8 GO:0032059 bleb(GO:0032059)
0.2 8.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 25.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 5.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 19.1 GO:0005901 caveola(GO:0005901)
0.2 14.0 GO:0043195 terminal bouton(GO:0043195)
0.2 2.6 GO:0005581 collagen trimer(GO:0005581)
0.2 4.2 GO:0005871 kinesin complex(GO:0005871)
0.2 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 2.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 4.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 8.1 GO:0016234 inclusion body(GO:0016234)
0.2 1.9 GO:0071437 invadopodium(GO:0071437)
0.2 5.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 4.4 GO:0097542 ciliary tip(GO:0097542)
0.2 2.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.1 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 17.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 66.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 4.1 GO:0097546 ciliary base(GO:0097546)
0.2 2.3 GO:0097346 Swr1 complex(GO:0000812) INO80-type complex(GO:0097346)
0.1 8.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 5.5 GO:0045095 keratin filament(GO:0045095)
0.1 50.7 GO:0005925 focal adhesion(GO:0005925)
0.1 3.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 7.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.1 3.3 GO:0000790 nuclear chromatin(GO:0000790)
0.1 2.1 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.1 2.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 11.0 GO:0034399 nuclear periphery(GO:0034399)
0.1 11.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 3.4 GO:0090544 BAF-type complex(GO:0090544)
0.1 3.6 GO:0031256 leading edge membrane(GO:0031256)
0.1 3.3 GO:0030027 lamellipodium(GO:0030027)
0.1 2.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 6.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 3.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 66.6 GO:0005730 nucleolus(GO:0005730)
0.1 3.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.5 GO:0005929 cilium(GO:0005929)
0.1 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 5.9 GO:0005884 actin filament(GO:0005884)
0.1 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.1 9.3 GO:0016607 nuclear speck(GO:0016607)
0.1 6.7 GO:0016604 nuclear body(GO:0016604)
0.1 4.3 GO:0016605 PML body(GO:0016605)
0.1 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 6.2 GO:0001726 ruffle(GO:0001726)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 8.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.5 GO:0000792 heterochromatin(GO:0000792)
0.1 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0005771 multivesicular body(GO:0005771)
0.0 14.8 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 1.2 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.3 21.8 GO:0070538 oleic acid binding(GO:0070538)
6.7 46.6 GO:0004849 uridine kinase activity(GO:0004849)
6.3 18.9 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
6.1 36.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
5.8 17.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
5.4 26.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.3 16.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
5.3 31.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
5.3 21.3 GO:0031493 nucleosomal histone binding(GO:0031493)
5.0 55.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
4.9 24.6 GO:0070404 NADH binding(GO:0070404)
4.5 13.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
4.2 12.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
4.1 32.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
4.0 28.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.8 3.8 GO:0055077 gap junction hemi-channel activity(GO:0055077)
3.7 29.5 GO:0044388 small protein activating enzyme binding(GO:0044388)
3.5 24.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
3.4 10.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
3.4 57.5 GO:0008494 translation activator activity(GO:0008494)
3.2 12.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
3.1 73.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
3.0 12.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.9 23.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.8 11.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
2.7 13.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
2.7 16.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
2.7 37.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.6 36.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
2.6 10.5 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.6 15.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
2.5 15.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.5 7.6 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
2.4 7.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
2.4 7.2 GO:0035501 MH1 domain binding(GO:0035501)
2.3 9.3 GO:0043515 kinetochore binding(GO:0043515)
2.3 11.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
2.2 119.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.2 24.2 GO:0015266 protein channel activity(GO:0015266)
2.1 6.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.1 21.1 GO:0042731 PH domain binding(GO:0042731)
2.1 16.6 GO:0001849 complement component C1q binding(GO:0001849)
2.0 8.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
2.0 6.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
2.0 16.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
2.0 12.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.0 6.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
2.0 11.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
2.0 8.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
2.0 5.9 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
2.0 5.9 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
1.9 9.6 GO:0000405 bubble DNA binding(GO:0000405)
1.9 26.3 GO:0005132 type I interferon receptor binding(GO:0005132)
1.8 5.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.8 12.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.8 14.4 GO:0030620 U2 snRNA binding(GO:0030620)
1.8 16.1 GO:1901612 cardiolipin binding(GO:1901612)
1.8 54.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.7 13.5 GO:0032137 guanine/thymine mispair binding(GO:0032137)
1.7 35.2 GO:0070628 proteasome binding(GO:0070628)
1.6 14.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.6 6.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.6 19.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.6 9.5 GO:0036310 annealing helicase activity(GO:0036310)
1.5 9.2 GO:0019238 cyclohydrolase activity(GO:0019238)
1.5 79.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
1.5 9.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
1.5 6.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.5 16.3 GO:0033038 bitter taste receptor activity(GO:0033038)
1.5 31.1 GO:0032794 GTPase activating protein binding(GO:0032794)
1.5 17.6 GO:0070990 snRNP binding(GO:0070990)
1.5 8.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.4 23.1 GO:0016887 ATPase activity(GO:0016887)
1.4 30.3 GO:0000339 RNA cap binding(GO:0000339)
1.4 5.8 GO:0008327 methyl-CpG binding(GO:0008327)
1.4 4.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.4 14.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.4 8.3 GO:0008046 axon guidance receptor activity(GO:0008046)
1.4 5.5 GO:1903135 cupric ion binding(GO:1903135)
1.3 64.7 GO:0008536 Ran GTPase binding(GO:0008536)
1.3 2.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.3 9.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.3 6.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
1.3 8.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.3 35.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.3 10.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.3 5.2 GO:0016531 copper chaperone activity(GO:0016531)
1.3 35.1 GO:0001848 complement binding(GO:0001848)
1.3 7.8 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.3 6.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
1.3 64.1 GO:0004364 glutathione transferase activity(GO:0004364)
1.2 12.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.2 2.5 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
1.2 36.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.2 3.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.2 6.0 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.2 3.5 GO:0000150 recombinase activity(GO:0000150)
1.2 12.9 GO:0045295 gamma-catenin binding(GO:0045295)
1.1 8.0 GO:0048408 epidermal growth factor binding(GO:0048408)
1.1 25.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.1 9.0 GO:0008432 JUN kinase binding(GO:0008432)
1.1 5.6 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
1.1 6.7 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.1 12.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.1 6.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.1 6.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 2.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
1.1 8.6 GO:0046790 virion binding(GO:0046790)
1.1 8.6 GO:0035174 histone serine kinase activity(GO:0035174)
1.1 9.6 GO:0008312 7S RNA binding(GO:0008312)
1.1 46.8 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
1.1 30.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0 3.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.0 6.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.0 3.0 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.0 9.0 GO:0045545 syndecan binding(GO:0045545)
1.0 47.7 GO:0019894 kinesin binding(GO:0019894)
1.0 27.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 9.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.0 3.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.0 18.1 GO:0070878 primary miRNA binding(GO:0070878)
0.9 3.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.9 3.7 GO:0043532 angiostatin binding(GO:0043532)
0.9 7.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.9 5.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.9 2.7 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.9 9.8 GO:0048156 tau protein binding(GO:0048156)
0.9 25.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.9 27.6 GO:0070840 dynein complex binding(GO:0070840)
0.9 2.6 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.8 5.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.8 2.5 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.8 6.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.8 65.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 5.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.8 2.5 GO:0004802 transketolase activity(GO:0004802)
0.8 8.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.8 8.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.8 2.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.8 3.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.7 21.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.7 2.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.7 2.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.7 19.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.7 5.0 GO:0050733 RS domain binding(GO:0050733)
0.7 5.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.7 5.5 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.7 26.9 GO:0000049 tRNA binding(GO:0000049)
0.7 2.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.7 8.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 8.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.7 9.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 8.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.7 6.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.7 3.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.7 4.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.7 5.9 GO:0042301 phosphate ion binding(GO:0042301)
0.7 3.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.6 3.9 GO:0070087 chromo shadow domain binding(GO:0070087)
0.6 25.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 11.5 GO:0097602 cullin family protein binding(GO:0097602)
0.6 9.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 1.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.6 1.8 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.6 2.5 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6 14.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 9.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 2.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 19.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.6 21.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.6 8.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 10.8 GO:0051400 BH domain binding(GO:0051400)
0.6 1.7 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.6 4.5 GO:0089720 caspase binding(GO:0089720)
0.6 3.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.6 6.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.6 18.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.6 7.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 12.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 9.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.5 7.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 44.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.5 9.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.5 3.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.5 7.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.5 16.1 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.5 1.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5 13.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.5 3.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 8.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 2.3 GO:0070905 serine binding(GO:0070905)
0.5 6.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 1.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.5 2.3 GO:0032407 MutSalpha complex binding(GO:0032407)
0.4 10.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.4 1.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 1.3 GO:0004966 galanin receptor activity(GO:0004966)
0.4 11.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.4 50.1 GO:0004386 helicase activity(GO:0004386)
0.4 16.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 3.4 GO:0004111 creatine kinase activity(GO:0004111)
0.4 5.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 1.6 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.4 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4 6.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 2.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.4 0.8 GO:0036033 mediator complex binding(GO:0036033)
0.4 0.4 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.4 1.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.4 2.7 GO:0016421 CoA carboxylase activity(GO:0016421)
0.4 1.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.4 9.7 GO:0031489 myosin V binding(GO:0031489)
0.4 4.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 1.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 15.0 GO:0050699 WW domain binding(GO:0050699)
0.3 3.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 7.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 5.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.3 2.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 2.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.3 2.9 GO:0035197 satellite DNA binding(GO:0003696) siRNA binding(GO:0035197)
0.3 6.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.3 0.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.3 122.5 GO:0045296 cadherin binding(GO:0045296)
0.3 1.9 GO:0050692 DBD domain binding(GO:0050692)
0.3 7.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 5.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 6.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.3 15.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 14.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.3 8.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 2.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.3 2.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 5.2 GO:0004697 protein kinase C activity(GO:0004697)
0.3 4.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 2.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 8.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 3.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.3 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 2.0 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.2 4.6 GO:0070410 co-SMAD binding(GO:0070410)
0.2 3.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 2.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 5.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.3 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.9 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.9 GO:0016936 galactoside binding(GO:0016936)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 4.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.8 GO:0051373 FATZ binding(GO:0051373)
0.2 2.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 3.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 12.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 0.6 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 2.2 GO:0031072 heat shock protein binding(GO:0031072)
0.2 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 2.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 4.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 5.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.2 3.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 5.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2 4.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 21.1 GO:0042393 histone binding(GO:0042393)
0.2 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 16.6 GO:0003774 motor activity(GO:0003774)
0.2 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 8.8 GO:0097110 scaffold protein binding(GO:0097110)
0.2 1.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 5.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 2.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 5.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 3.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 6.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 11.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 2.5 GO:0005521 lamin binding(GO:0005521)
0.1 6.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 4.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 7.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 1.2 GO:0031013 troponin I binding(GO:0031013)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 7.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 16.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 5.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 78.8 GO:0003723 RNA binding(GO:0003723)
0.1 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.1 0.8 GO:0048185 activin binding(GO:0048185)
0.1 2.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 11.1 GO:0003924 GTPase activity(GO:0003924)
0.0 2.4 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.4 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 112.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.6 18.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.4 87.1 PID ATR PATHWAY ATR signaling pathway
1.1 46.7 PID BARD1 PATHWAY BARD1 signaling events
1.0 28.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.8 45.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.7 35.4 PID MYC PATHWAY C-MYC pathway
0.6 17.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.6 25.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.6 17.1 PID ATM PATHWAY ATM pathway
0.6 27.0 PID AURORA A PATHWAY Aurora A signaling
0.5 19.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 28.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.5 36.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 30.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 5.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.4 8.8 PID ALK1 PATHWAY ALK1 signaling events
0.3 23.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 10.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 6.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 3.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.3 6.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.3 4.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 7.6 PID IL1 PATHWAY IL1-mediated signaling events
0.3 10.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 7.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 8.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 3.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 10.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 3.2 PID IGF1 PATHWAY IGF1 pathway
0.2 18.9 PID E2F PATHWAY E2F transcription factor network
0.2 13.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.2 6.8 PID IL23 PATHWAY IL23-mediated signaling events
0.2 8.1 PID CDC42 PATHWAY CDC42 signaling events
0.2 7.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 5.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.2 5.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 8.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 15.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 4.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 8.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 18.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 5.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 9.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 5.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 5.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 6.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 5.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 5.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.0 PID ARF 3PATHWAY Arf1 pathway
0.1 4.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 5.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.6 PID AURORA B PATHWAY Aurora B signaling
0.1 2.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.9 PID INSULIN PATHWAY Insulin Pathway
0.1 2.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.7 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 ST GAQ PATHWAY G alpha q Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 112.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
3.8 38.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.9 44.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
2.7 24.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
2.7 54.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.7 45.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.4 85.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
2.4 244.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.9 36.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.8 151.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.8 10.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.7 35.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.6 39.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
1.6 107.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.6 48.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
1.5 13.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.5 20.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
1.4 11.5 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
1.4 2.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.4 20.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
1.4 23.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.3 39.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.2 22.4 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
1.2 14.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.2 26.7 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.2 31.6 REACTOME KINESINS Genes involved in Kinesins
1.2 12.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.2 62.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.2 36.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.0 10.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.0 27.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
1.0 56.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.0 19.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
1.0 17.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.9 13.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.9 14.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.9 11.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.9 26.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.8 18.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.8 11.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 13.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.8 70.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.8 22.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.8 4.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.8 3.2 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.7 9.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.7 15.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.7 11.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7 10.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.7 22.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.6 39.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 3.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.6 60.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.6 9.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.6 13.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.6 5.9 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.6 12.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.6 11.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.6 13.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.6 1.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.6 15.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.5 16.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.5 12.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.5 11.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 13.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 6.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 3.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.4 5.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.4 8.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.4 6.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.4 4.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.4 8.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 10.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 10.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 12.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 19.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 8.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 7.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 4.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 9.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 7.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 13.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 42.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.3 4.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 3.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 3.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 4.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 4.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 3.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 5.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 2.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 8.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.2 3.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 31.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 4.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 4.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 13.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 3.3 REACTOME TRANSLATION Genes involved in Translation
0.2 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 5.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 3.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 4.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 5.2 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 2.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 5.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 15.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 8.9 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 3.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 4.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 3.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 3.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 2.0 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 4.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events