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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for PPARG

Z-value: 0.70

Motif logo

Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
ENSG00000132170.15 peroxisome proliferator activated receptor gamma

Activity-expression correlation:

Activity profile of PPARG motif

Sorted Z-values of PPARG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_23241661 22.73 ENST00000390322.2
immunoglobulin lambda joining 2
chr22_+_23264766 22.61 ENST00000390331.2
immunoglobulin lambda constant 7
chr19_+_50016411 20.91 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr7_-_150498426 20.41 ENST00000447204.2
transmembrane protein 176B
chr22_+_23229960 18.76 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr19_+_50016610 15.59 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr7_+_150498610 15.27 ENST00000461345.1
transmembrane protein 176A
chr11_-_5255696 14.61 ENST00000292901.3
ENST00000417377.1
hemoglobin, delta
chr14_-_106642049 14.36 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr19_-_10445399 14.28 ENST00000592945.1
intercellular adhesion molecule 3
chr1_+_203274639 14.25 ENST00000290551.4
BTG family, member 2
chr9_-_33447584 14.08 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr19_-_36399149 14.08 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYRO protein tyrosine kinase binding protein
chr7_+_150498783 13.82 ENST00000475536.1
ENST00000468689.1
transmembrane protein 176A
chr2_-_89513402 13.17 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr17_+_42427826 11.01 ENST00000586443.1
granulin
chr11_+_308143 10.84 ENST00000399817.4
interferon induced transmembrane protein 2
chr14_+_23340822 10.74 ENST00000359591.4
low density lipoprotein receptor-related protein 10
chr11_-_5255861 10.33 ENST00000380299.3
hemoglobin, delta
chr8_-_11725549 9.92 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
cathepsin B
chr22_+_50312274 9.39 ENST00000404488.3
cysteine-rich with EGF-like domains 2
chr6_+_31783291 9.12 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr14_+_105953246 8.98 ENST00000392531.3
cysteine-rich protein 1 (intestinal)
chr22_+_50312316 8.94 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr11_+_117070037 8.86 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
transgelin
chr5_-_150460539 8.55 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNFAIP3 interacting protein 1
chr14_+_105953204 8.53 ENST00000409393.2
cysteine-rich protein 1 (intestinal)
chr19_+_11658655 8.31 ENST00000588935.1
calponin 1, basic, smooth muscle
chr7_+_75932863 8.25 ENST00000429938.1
heat shock 27kDa protein 1
chr19_-_45826125 8.24 ENST00000221476.3
creatine kinase, muscle
chr10_-_72362515 8.10 ENST00000373209.2
ENST00000441259.1
perforin 1 (pore forming protein)
chr14_-_106330458 8.08 ENST00000461719.1
immunoglobulin heavy joining 4
chr17_-_62097927 8.06 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr7_-_99569468 7.84 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr19_+_18682531 7.74 ENST00000596304.1
ENST00000430157.2
ubiquitin A-52 residue ribosomal protein fusion product 1
chr14_+_95047725 7.46 ENST00000554760.1
ENST00000554866.1
ENST00000329597.7
ENST00000556775.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr15_-_60690163 7.44 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
annexin A2
chr5_-_180242534 7.37 ENST00000333055.3
ENST00000513431.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_+_158815588 7.16 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr21_-_46293644 7.11 ENST00000330938.3
pituitary tumor-transforming 1 interacting protein
chr16_+_30383613 6.93 ENST00000568749.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_-_34207295 6.86 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr14_+_21152259 6.68 ENST00000555835.1
ENST00000336811.6
ribonuclease, RNase A family, 4
angiogenin, ribonuclease, RNase A family, 5
chr11_+_2923619 6.68 ENST00000380574.1
solute carrier family 22, member 18
chr14_+_24630465 6.61 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
interferon regulatory factor 9
chr13_-_44453826 6.52 ENST00000444614.3
coiled-coil domain containing 122
chr19_-_50143452 6.50 ENST00000246792.3
related RAS viral (r-ras) oncogene homolog
chrX_-_106959631 6.44 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr6_-_159065741 6.34 ENST00000367085.3
ENST00000367089.3
dynein, light chain, Tctex-type 1
chr21_-_46293586 6.32 ENST00000445724.2
ENST00000397887.3
pituitary tumor-transforming 1 interacting protein
chr17_-_7297519 6.32 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3 readthrough (NMD candidate)
chr14_-_107283278 6.22 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr14_-_106866934 6.21 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr19_+_7968728 6.16 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
mitogen-activated protein kinase kinase 7
chr19_+_18682661 5.98 ENST00000596273.1
ENST00000442744.2
ENST00000595683.1
ENST00000599256.1
ENST00000595158.1
ENST00000598780.1
ubiquitin A-52 residue ribosomal protein fusion product 1
chr19_+_1407517 5.96 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr17_-_7297833 5.93 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_-_44031341 5.91 ENST00000600651.1
ethylmalonic encephalopathy 1
chr11_+_2923499 5.89 ENST00000449793.2
solute carrier family 22, member 18
chr19_+_49661037 5.77 ENST00000427978.2
transient receptor potential cation channel, subfamily M, member 4
chr9_+_101984577 5.75 ENST00000223641.4
Sec61 beta subunit
chr14_-_100842588 5.75 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
tryptophanyl-tRNA synthetase
chr3_-_133748913 5.63 ENST00000310926.4
solute carrier organic anion transporter family, member 2A1
chr6_+_31982539 5.62 ENST00000435363.2
ENST00000425700.2
complement component 4B (Chido blood group)
chr17_+_45286706 5.58 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr12_-_53601000 5.55 ENST00000338737.4
ENST00000549086.2
integrin, beta 7
chr16_+_29831715 5.55 ENST00000563915.1
ENST00000357402.5
major vault protein
chr17_-_39942940 5.52 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
junction plakoglobin
chr17_-_62097904 5.49 ENST00000583366.1
intercellular adhesion molecule 2
chr5_+_178977546 5.46 ENST00000319449.4
ENST00000377001.2
RUN and FYVE domain containing 1
chr22_-_21579843 5.41 ENST00000405188.4
gamma-glutamyltransferase 2
chr6_+_31795506 5.38 ENST00000375650.3
heat shock 70kDa protein 1B
chr16_+_29831757 5.36 ENST00000452209.2
ENST00000395353.1
ENST00000566066.1
ENST00000563558.1
major vault protein
chr19_+_49661079 5.31 ENST00000355712.5
transient receptor potential cation channel, subfamily M, member 4
chr4_-_25865159 5.25 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr22_+_50312379 5.17 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr8_-_134115118 5.15 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr13_+_28194873 5.10 ENST00000302979.3
polymerase (RNA) I polypeptide D, 16kDa
chr5_-_70272055 5.09 ENST00000514857.2
NLR family, apoptosis inhibitory protein
chr6_+_31949801 5.04 ENST00000428956.2
ENST00000498271.1
complement component 4A (Rodgers blood group)
chr22_-_36784035 5.03 ENST00000216181.5
myosin, heavy chain 9, non-muscle
chr19_+_49660997 5.01 ENST00000598691.1
ENST00000252826.5
transient receptor potential cation channel, subfamily M, member 4
chr19_-_13213662 5.00 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr1_+_47603109 4.98 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
cytochrome P450, family 4, subfamily A, polypeptide 22
chr2_-_217724767 4.97 ENST00000236979.2
transition protein 1 (during histone to protamine replacement)
chr12_-_56122761 4.94 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63 molecule
chr20_+_44563267 4.94 ENST00000372409.3
PDX1 C-terminal inhibiting factor 1
chr22_+_22676808 4.93 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr2_+_85922491 4.89 ENST00000526018.1
granulysin
chr19_+_17970677 4.87 ENST00000222247.5
ribosomal protein L18a
chr19_+_35609380 4.86 ENST00000604621.1
FXYD domain containing ion transport regulator 3
chr1_+_207494853 4.78 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr22_+_37309662 4.77 ENST00000403662.3
ENST00000262825.5
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr16_+_1203194 4.74 ENST00000348261.5
ENST00000358590.4
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr22_+_22681656 4.69 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr2_-_219151487 4.68 ENST00000444881.1
transmembrane BAX inhibitor motif containing 1
chr19_-_54784353 4.64 ENST00000391746.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_+_219247021 4.62 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr15_+_44580955 4.61 ENST00000345795.2
ENST00000360824.3
cancer susceptibility candidate 4
chr6_-_31782813 4.51 ENST00000375654.4
heat shock 70kDa protein 1-like
chr17_+_77681075 4.51 ENST00000397549.2
CTD-2116F7.1
chr4_+_87856129 4.47 ENST00000395146.4
ENST00000507468.1
AF4/FMR2 family, member 1
chr15_+_44580899 4.38 ENST00000559222.1
ENST00000299957.6
cancer susceptibility candidate 4
chr14_-_106453155 4.37 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr12_+_50135327 4.37 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
transmembrane BAX inhibitor motif containing 6
chr7_+_12727250 4.37 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr2_+_201994208 4.31 ENST00000440180.1
CASP8 and FADD-like apoptosis regulator
chr12_+_50135351 4.26 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
transmembrane BAX inhibitor motif containing 6
chr1_+_207925391 4.26 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
CD46 molecule, complement regulatory protein
chr6_-_112575912 4.25 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr9_-_130616915 4.24 ENST00000344849.3
endoglin
chr9_-_139094988 4.19 ENST00000371746.3
LIM homeobox 3
chr11_-_82612727 4.10 ENST00000531128.1
ENST00000535099.1
ENST00000527444.1
prolylcarboxypeptidase (angiotensinase C)
chr11_+_82612740 4.02 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
chromosome 11 open reading frame 82
chr12_-_56123444 3.97 ENST00000546457.1
ENST00000549117.1
CD63 molecule
chr16_-_67969888 3.90 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr15_+_90931450 3.86 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr6_-_24911195 3.81 ENST00000259698.4
family with sequence similarity 65, member B
chr12_+_112451120 3.80 ENST00000261735.3
ENST00000455836.1
endoplasmic reticulum protein 29
chr15_+_41056218 3.79 ENST00000260447.4
GTP cyclohydrolase I feedback regulator
chr2_-_87018784 3.72 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr11_+_46740730 3.66 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr10_+_114135952 3.66 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
acyl-CoA synthetase long-chain family member 5
chr15_+_41056255 3.65 ENST00000561160.1
ENST00000559445.1
GTP cyclohydrolase I feedback regulator
chr4_-_860950 3.65 ENST00000511980.1
ENST00000510799.1
cyclin G associated kinase
chr19_-_1592828 3.61 ENST00000592012.1
methyl-CpG binding domain protein 3
chr3_+_125687987 3.42 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
rhophilin associated tail protein 1B
chrY_+_9304564 3.42 ENST00000451548.1
testis specific protein, Y-linked 1
chr4_+_15704679 3.40 ENST00000382346.3
bone marrow stromal cell antigen 1
chr11_+_76494253 3.33 ENST00000333090.4
tsukushi, small leucine rich proteoglycan
chr3_+_9958758 3.24 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
interleukin 17 receptor C
chr19_+_544034 3.22 ENST00000592501.1
ENST00000264553.3
granzyme M (lymphocyte met-ase 1)
chr9_-_130679257 3.18 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr3_-_122512619 3.18 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr19_-_44031375 3.18 ENST00000292147.2
ethylmalonic encephalopathy 1
chrX_+_152907913 3.13 ENST00000370167.4
dual specificity phosphatase 9
chrY_+_9324922 3.07 ENST00000440215.2
ENST00000446779.2
testis specific protein, Y-linked 6, pseudogene
chr16_+_29817399 3.02 ENST00000545521.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_+_48507210 2.93 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
three prime repair exonuclease 1
chr1_-_113247543 2.93 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr22_+_23089870 2.84 ENST00000390311.2
immunoglobulin lambda variable 3-16
chr19_-_1592652 2.79 ENST00000156825.1
ENST00000434436.3
methyl-CpG binding domain protein 3
chr12_-_57352103 2.78 ENST00000398138.3
retinol dehydrogenase 16 (all-trans)
chr9_-_139096955 2.76 ENST00000371748.5
LIM homeobox 3
chr3_+_52811596 2.74 ENST00000542827.1
ENST00000273283.2
inter-alpha-trypsin inhibitor heavy chain 1
chr11_+_695614 2.74 ENST00000608174.1
ENST00000397512.3
transmembrane protein 80
chr4_+_15704573 2.72 ENST00000265016.4
bone marrow stromal cell antigen 1
chr17_-_59668550 2.70 ENST00000521764.1
nascent polypeptide-associated complex alpha subunit 2
chrX_+_9433048 2.69 ENST00000217964.7
transducin (beta)-like 1X-linked
chr3_+_9958870 2.68 ENST00000413608.1
interleukin 17 receptor C
chrX_+_135252050 2.65 ENST00000449474.1
ENST00000345434.3
four and a half LIM domains 1
chrY_+_9195406 2.65 ENST00000287721.9
ENST00000383005.2
ENST00000383000.1
ENST00000330628.9
ENST00000537415.1
testis specific protein, Y-linked 8
chrY_+_6114264 2.65 ENST00000320701.4
ENST00000383042.1
testis specific protein, Y-linked 2
chr22_-_23484246 2.60 ENST00000216036.4
rhabdoid tumor deletion region gene 1
chr17_-_7082861 2.55 ENST00000269299.3
asialoglycoprotein receptor 1
chr1_-_47407111 2.53 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr6_-_112575687 2.51 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
laminin, alpha 4
chr8_-_145652336 2.50 ENST00000529182.1
ENST00000526054.1
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr8_-_145115584 2.49 ENST00000426825.1
5-oxoprolinase (ATP-hydrolysing)
chr11_+_126225789 2.48 ENST00000530591.1
ENST00000534083.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chrY_+_9175073 2.46 ENST00000426950.2
ENST00000383008.1
testis specific protein, Y-linked 4
chr12_-_96390063 2.44 ENST00000541929.1
histidine ammonia-lyase
chr2_+_201994042 2.44 ENST00000417748.1
CASP8 and FADD-like apoptosis regulator
chr8_+_70404996 2.42 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr3_+_48282587 2.42 ENST00000354698.3
ENST00000427617.2
ENST00000412564.1
ENST00000440261.2
zinc finger protein 589
chr17_-_61988556 2.41 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
chorionic somatomammotropin hormone-like 1
chr19_-_54746600 2.39 ENST00000245621.5
ENST00000270464.5
ENST00000419410.2
ENST00000391735.3
ENST00000396365.2
ENST00000440558.2
ENST00000407860.2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr6_-_112575758 2.39 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
laminin, alpha 4
chr11_+_844406 2.38 ENST00000397404.1
tetraspanin 4
chr20_+_814377 2.37 ENST00000304189.2
ENST00000381939.1
family with sequence similarity 110, member A
chr16_+_1359511 2.29 ENST00000397514.3
ENST00000397515.2
ENST00000567383.1
ENST00000403747.2
ENST00000566587.1
ubiquitin-conjugating enzyme E2I
chr19_+_42772659 2.27 ENST00000572681.2
capicua transcriptional repressor
chr1_-_111970353 2.26 ENST00000369732.3
oviductal glycoprotein 1, 120kDa
chr21_+_45705752 2.24 ENST00000291582.5
autoimmune regulator
chr17_+_18128896 2.22 ENST00000316843.4
lethal giant larvae homolog 1 (Drosophila)
chr3_-_123710893 2.20 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
rhophilin associated tail protein 1
chrY_-_16098393 2.19 ENST00000250825.4
variable charge, Y-linked
chr15_-_74658493 2.18 ENST00000419019.2
ENST00000569662.1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr11_+_1942580 2.17 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr10_-_48438974 2.16 ENST00000224605.2
growth differentiation factor 10
chr5_+_175976324 2.15 ENST00000261944.5
cadherin-related family member 2
chr11_+_7534999 2.14 ENST00000528947.1
ENST00000299492.4
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr22_-_50312052 2.10 ENST00000330817.6
ALG12, alpha-1,6-mannosyltransferase
chr11_-_36619771 2.09 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
recombination activating gene 2
chr15_-_74658519 2.06 ENST00000450547.1
ENST00000358632.4
cytochrome P450, family 11, subfamily A, polypeptide 1
chr12_+_123459127 2.05 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr1_+_228270361 2.04 ENST00000272102.5
ENST00000540651.1
ADP-ribosylation factor 1
chr3_-_123411191 2.03 ENST00000354792.5
ENST00000508240.1
myosin light chain kinase
chr14_+_24899141 2.03 ENST00000556842.1
ENST00000553935.1
KH and NYN domain containing
chr11_+_14665373 2.03 ENST00000455098.2
phosphodiesterase 3B, cGMP-inhibited
chr3_+_148415571 2.03 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
angiotensin II receptor, type 1
chr19_+_532049 2.02 ENST00000606136.1
cell division cycle 34
chr22_+_30792846 2.02 ENST00000312932.9
ENST00000428195.1
SEC14-like 2 (S. cerevisiae)
chr22_+_19929130 1.98 ENST00000361682.6
ENST00000403184.1
ENST00000403710.1
ENST00000407537.1
catechol-O-methyltransferase
chr3_+_48507621 1.97 ENST00000456089.1
three prime repair exonuclease 1
chr22_+_30792980 1.97 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14-like 2 (S. cerevisiae)
chr3_+_8775466 1.96 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr3_-_145968923 1.96 ENST00000493382.1
ENST00000354952.2
ENST00000383083.2
phospholipid scramblase 4
chr16_+_85646763 1.96 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chrY_+_16168097 1.95 ENST00000250823.4
variable charge, Y-linked 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 36.5 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.0 16.1 GO:1903781 positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
3.6 14.5 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
3.5 49.5 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.5 17.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
2.9 8.6 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
2.8 14.1 GO:0070295 renal water absorption(GO:0070295)
2.5 7.4 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
2.5 7.4 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
2.4 9.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
2.0 6.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
1.9 7.5 GO:0061107 seminal vesicle development(GO:0061107)
1.8 7.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.7 6.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.7 5.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.7 24.9 GO:0015671 oxygen transport(GO:0015671)
1.6 8.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
1.6 4.9 GO:0002818 intracellular defense response(GO:0002818)
1.6 4.8 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.6 12.6 GO:0046618 drug export(GO:0046618)
1.5 4.6 GO:0055073 cadmium ion homeostasis(GO:0055073)
1.5 9.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.5 11.9 GO:0007506 gonadal mesoderm development(GO:0007506)
1.4 8.6 GO:0031437 regulation of mRNA cleavage(GO:0031437) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720)
1.4 4.2 GO:0001300 chronological cell aging(GO:0001300)
1.4 5.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.3 6.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.2 3.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
1.2 4.7 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
1.2 4.6 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.2 7.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
1.2 5.8 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
1.1 3.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.1 5.5 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
1.1 6.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
1.0 4.1 GO:0003095 pressure natriuresis(GO:0003095)
1.0 4.1 GO:0002353 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
1.0 3.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.0 2.0 GO:0097212 lysosomal membrane organization(GO:0097212)
1.0 71.7 GO:0006910 phagocytosis, recognition(GO:0006910)
1.0 5.0 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
1.0 10.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.0 4.8 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.9 3.8 GO:0043335 protein unfolding(GO:0043335)
0.9 3.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.9 14.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.9 13.7 GO:0017085 response to insecticide(GO:0017085)
0.8 5.9 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.8 5.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.8 2.5 GO:2000395 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.8 14.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.8 6.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8 4.7 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.8 6.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.8 2.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.7 8.2 GO:0006600 creatine metabolic process(GO:0006600)
0.7 2.2 GO:2000410 tolerance induction to self antigen(GO:0002513) regulation of thymocyte migration(GO:2000410)
0.7 2.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.7 8.9 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.7 6.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.6 10.9 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.6 3.8 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.6 6.9 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.6 4.3 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.6 6.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.5 2.1 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.5 5.0 GO:0001955 blood vessel maturation(GO:0001955)
0.5 2.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.5 2.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.5 1.5 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.5 13.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.5 1.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.4 1.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.4 2.6 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.4 9.9 GO:0046697 decidualization(GO:0046697)
0.4 6.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4 6.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.4 7.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.4 8.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.4 2.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.4 10.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.4 6.0 GO:0001893 maternal placenta development(GO:0001893)
0.4 1.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.4 5.6 GO:0015732 prostaglandin transport(GO:0015732)
0.4 1.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 3.9 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.3 1.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.3 1.3 GO:0060023 soft palate development(GO:0060023)
0.3 1.0 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.3 1.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 1.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3 0.9 GO:0050894 determination of affect(GO:0050894)
0.3 7.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 0.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.8 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 1.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 0.9 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.3 1.5 GO:0044026 DNA hypermethylation(GO:0044026)
0.3 5.1 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.3 3.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 1.9 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.3 3.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.3 1.0 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.3 1.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3 2.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.3 0.8 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.3 2.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 6.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.2 3.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 2.7 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.2 5.7 GO:0097503 sialylation(GO:0097503)
0.2 1.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 6.5 GO:0060325 face morphogenesis(GO:0060325)
0.2 1.4 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.2 1.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 4.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.9 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.2 1.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 5.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.5 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 2.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 1.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.7 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 27.0 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 3.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 1.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 1.1 GO:0060294 cilium movement involved in cell motility(GO:0060294) regulation of microtubule binding(GO:1904526)
0.1 1.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.4 GO:0070781 response to biotin(GO:0070781)
0.1 4.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 21.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.8 GO:0046415 urate metabolic process(GO:0046415)
0.1 10.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 2.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 4.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.7 GO:0043068 positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 1.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 5.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 4.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 9.0 GO:0045995 regulation of embryonic development(GO:0045995)
0.1 0.3 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 2.4 GO:0019835 cytolysis(GO:0019835)
0.1 1.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.3 GO:0071711 basement membrane organization(GO:0071711)
0.1 0.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 2.4 GO:0006298 mismatch repair(GO:0006298)
0.1 2.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 4.0 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 8.6 GO:0048839 inner ear development(GO:0048839)
0.1 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.7 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 1.7 GO:0048255 mRNA stabilization(GO:0048255)
0.0 2.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 6.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.5 GO:0007320 insemination(GO:0007320)
0.0 2.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 1.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 3.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 4.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.1 GO:0007517 muscle organ development(GO:0007517)
0.0 0.0 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.6 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 1.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.4 GO:2001252 positive regulation of chromosome organization(GO:2001252)
0.0 1.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.1 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.8 24.9 GO:0005833 hemoglobin complex(GO:0005833)
1.7 5.0 GO:0005826 actomyosin contractile ring(GO:0005826)
1.5 7.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
1.4 13.0 GO:0044194 cytolytic granule(GO:0044194)
1.4 4.3 GO:0002079 inner acrosomal membrane(GO:0002079)
1.4 9.9 GO:0036021 endolysosome lumen(GO:0036021)
1.4 4.2 GO:0072563 endothelial microparticle(GO:0072563)
1.4 69.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.4 5.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.2 5.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
1.1 6.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.9 19.7 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 8.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 5.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.6 16.1 GO:0034706 sodium channel complex(GO:0034706)
0.5 3.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.5 3.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 1.4 GO:0044305 calyx of Held(GO:0044305)
0.4 2.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 13.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.4 2.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 6.7 GO:0097342 ripoptosome(GO:0097342)
0.4 2.5 GO:0000813 ESCRT I complex(GO:0000813)
0.4 5.0 GO:0001673 nuclear nucleosome(GO:0000788) male germ cell nucleus(GO:0001673)
0.3 4.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 1.7 GO:0071546 pi-body(GO:0071546)
0.3 2.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 3.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 5.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.7 GO:0061617 MICOS complex(GO:0061617)
0.2 1.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 1.9 GO:0072687 meiotic spindle(GO:0072687)
0.2 6.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 6.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 1.0 GO:0032449 CBM complex(GO:0032449)
0.2 18.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 6.9 GO:0005859 muscle myosin complex(GO:0005859)
0.2 32.5 GO:0072562 blood microparticle(GO:0072562)
0.2 15.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 8.2 GO:1904115 axon cytoplasm(GO:1904115)
0.2 3.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 1.3 GO:0005638 lamin filament(GO:0005638)
0.1 2.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 3.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 6.0 GO:0031672 A band(GO:0031672)
0.1 3.3 GO:0032420 stereocilium(GO:0032420)
0.1 4.1 GO:0005605 basal lamina(GO:0005605)
0.1 6.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 10.9 GO:0005643 nuclear pore(GO:0005643)
0.1 3.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 4.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0030897 HOPS complex(GO:0030897)
0.1 2.3 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.6 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 22.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 21.2 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 2.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 4.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 2.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 8.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 54.2 GO:0005615 extracellular space(GO:0005615)
0.0 4.5 GO:0031514 motile cilium(GO:0031514)
0.0 4.8 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 3.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 2.6 GO:0030496 midbody(GO:0030496)
0.0 88.3 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.3 GO:0030133 transport vesicle(GO:0030133)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 4.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.7 GO:0005925 focal adhesion(GO:0005925)
0.0 3.5 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 36.5 GO:0019770 IgG receptor activity(GO:0019770)
3.5 14.1 GO:0015254 glycerol channel activity(GO:0015254)
2.7 8.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
2.5 12.6 GO:0015307 drug:proton antiporter activity(GO:0015307)
2.5 7.4 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
2.0 6.1 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
1.9 24.9 GO:0005344 oxygen transporter activity(GO:0005344)
1.8 7.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.6 8.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
1.6 4.8 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.6 4.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.5 4.6 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
1.4 8.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.4 4.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
1.4 5.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.3 14.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.3 3.8 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.3 69.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.2 7.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.1 9.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.1 6.7 GO:0004522 ribonuclease A activity(GO:0004522)
1.1 3.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.0 17.5 GO:0003680 AT DNA binding(GO:0003680)
1.0 8.2 GO:0004111 creatine kinase activity(GO:0004111)
1.0 4.0 GO:0008431 vitamin E binding(GO:0008431)
1.0 6.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.9 3.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.8 5.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.8 7.5 GO:0032190 acrosin binding(GO:0032190)
0.8 5.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.8 4.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.8 3.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.7 6.4 GO:0043426 MRF binding(GO:0043426)
0.7 2.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.6 5.0 GO:0001849 complement component C1q binding(GO:0001849)
0.6 2.5 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.6 1.9 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.6 5.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.6 2.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 4.6 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.6 2.3 GO:0043398 HLH domain binding(GO:0043398)
0.5 4.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 2.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 4.2 GO:0005534 galactose binding(GO:0005534)
0.5 2.0 GO:0071253 connexin binding(GO:0071253)
0.5 12.6 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.5 1.4 GO:0035500 MH2 domain binding(GO:0035500)
0.4 7.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.4 6.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 2.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 16.1 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.4 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 1.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 2.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 5.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.4 8.1 GO:0022829 wide pore channel activity(GO:0022829)
0.4 9.9 GO:0001848 complement binding(GO:0001848)
0.4 11.4 GO:0005123 death receptor binding(GO:0005123)
0.3 1.4 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 1.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.3 6.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.3 8.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.3 3.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 5.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 2.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.3 1.4 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.3 6.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 12.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 6.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 5.0 GO:0043495 protein anchor(GO:0043495)
0.3 4.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 3.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 1.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 2.3 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 0.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.2 3.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 29.6 GO:0005178 integrin binding(GO:0005178)
0.2 2.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 3.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 22.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.5 GO:0019841 retinol binding(GO:0019841)
0.1 0.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 9.9 GO:0005518 collagen binding(GO:0005518)
0.1 9.5 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 11.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 5.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 9.5 GO:0019003 GDP binding(GO:0019003)
0.1 10.5 GO:0002039 p53 binding(GO:0002039)
0.1 1.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.9 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 2.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.1 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.7 GO:0044325 ion channel binding(GO:0044325)
0.1 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 3.6 GO:0030332 cyclin binding(GO:0030332)
0.1 19.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.1 14.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 7.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 10.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 0.3 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 11.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 13.2 GO:0008083 growth factor activity(GO:0008083)
0.1 1.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 8.9 GO:0051015 actin filament binding(GO:0051015)
0.1 3.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 8.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 1.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0009374 biotin binding(GO:0009374)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 4.2 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 5.8 GO:0001047 core promoter binding(GO:0001047)
0.0 2.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 1.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.9 GO:0060089 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 27.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 6.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 6.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 8.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 10.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 5.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 6.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 5.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 10.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 11.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 4.8 PID IL5 PATHWAY IL5-mediated signaling events
0.2 9.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 8.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 2.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 7.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 26.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.2 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 27.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 6.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 2.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 11.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 7.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 6.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 4.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 12.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 5.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 16.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
1.0 14.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 9.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 58.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6 12.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.5 14.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 5.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.4 7.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 6.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 7.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 10.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 5.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 5.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 8.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 5.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 2.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 3.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 5.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 11.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 8.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 15.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 3.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 17.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 9.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 7.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 4.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 3.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 5.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 8.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 3.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 6.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.9 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 2.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors