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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for PRDM1

Z-value: 0.07

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Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
PRDM1
ENSG00000057657.10 PR/SET domain 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106534192_1065342240.162.0e-02Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_32821924 10.92 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr1_-_111746966 8.48 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr17_-_26694979 8.13 ENST00000438614.1
VTN
vitronectin
chr17_-_26695013 8.12 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_79818354 7.54 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr6_+_32811885 6.96 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr16_-_67970990 6.84 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr14_+_24605361 6.72 ENST00000206451.6
ENST00000559123.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_-_33282163 6.53 ENST00000434618.2
ENST00000456592.2
TAPBP
TAP binding protein (tapasin)
chr14_+_24605389 5.92 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_231084617 5.89 ENST00000409815.2
SP110
SP110 nuclear body protein
chr10_-_44880491 5.71 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
CXCL12
chemokine (C-X-C motif) ligand 12
chr12_+_25205446 5.43 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr2_-_231084820 5.36 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr3_-_49851313 5.16 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr16_+_50776021 5.07 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr6_-_32811771 4.94 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr16_+_50775971 4.83 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_50775948 4.83 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr12_-_57505121 4.59 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_-_31688431 4.54 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_-_21490417 4.42 ENST00000556366.1
NDRG2
NDRG family member 2
chr22_-_36556821 4.39 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr2_-_231084659 4.39 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr10_-_82049424 4.32 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr5_+_49962495 4.25 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_+_46402482 4.24 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_118827333 4.18 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr6_-_41909191 4.17 ENST00000512426.1
ENST00000372987.4
CCND3
cyclin D3
chr16_-_88851618 4.08 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr7_-_86849025 4.07 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr13_+_31309645 3.96 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr5_+_96211643 3.96 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr4_-_100242549 3.87 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_-_39274617 3.72 ENST00000510188.1
FYB
FYN binding protein
chr5_+_96212185 3.68 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr9_-_34710066 3.61 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr3_+_8543533 3.53 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr2_+_231191875 3.44 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr14_-_21490653 3.39 ENST00000449431.2
NDRG2
NDRG family member 2
chr22_-_31688381 3.16 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr19_+_24009879 3.07 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr3_+_8543561 2.96 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr2_+_231280908 2.93 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr11_+_128563652 2.77 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_+_97506033 2.66 ENST00000518385.1
SDC2
syndecan 2
chr12_+_6561190 2.52 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr12_-_106641728 2.49 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr9_+_137533615 2.38 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr5_-_39203093 2.35 ENST00000515010.1
FYB
FYN binding protein
chr22_+_39436862 2.34 ENST00000381565.2
ENST00000452957.2
APOBEC3F
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr11_+_128563948 2.24 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_24615805 2.24 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_+_128634589 2.23 ENST00000281428.8
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr8_+_96145974 2.15 ENST00000315367.3
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr19_+_49977818 2.12 ENST00000594009.1
ENST00000595510.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr6_-_112575912 2.11 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr14_-_21490590 2.10 ENST00000557633.1
NDRG2
NDRG family member 2
chr17_+_41158742 2.08 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr3_-_114343039 2.08 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_46402583 2.06 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr5_-_96143602 2.01 ENST00000443439.2
ENST00000503921.1
ENST00000508227.1
ENST00000507154.1
ERAP1
endoplasmic reticulum aminopeptidase 1
chr1_+_212782012 1.98 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr12_-_120763739 1.94 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr5_-_96143796 1.89 ENST00000296754.3
ERAP1
endoplasmic reticulum aminopeptidase 1
chr17_+_7211656 1.88 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr6_-_29527702 1.88 ENST00000377050.4
UBD
ubiquitin D
chr1_-_221915418 1.86 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr14_-_21490958 1.82 ENST00000554104.1
NDRG2
NDRG family member 2
chr6_-_137113604 1.78 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr3_+_8543393 1.67 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr10_-_50747064 1.64 ENST00000355832.5
ENST00000603152.1
ENST00000447839.2
ERCC6
PGBD3
ERCC6-PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
ERCC6-PGBD3 readthrough
chr20_+_30946106 1.63 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr1_+_181003067 1.59 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
MR1
major histocompatibility complex, class I-related
chr11_+_64008525 1.59 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr1_+_2985760 1.57 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr4_+_152020789 1.53 ENST00000512690.1
ENST00000508783.1
ENST00000512797.1
ENST00000507327.1
ENST00000515792.1
ENST00000506126.1
RPS3A
ribosomal protein S3A
chr13_+_102104980 1.53 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_+_134464376 1.50 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr2_-_175260368 1.47 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr4_+_152020715 1.47 ENST00000274065.4
RPS3A
ribosomal protein S3A
chr19_+_17186577 1.42 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr4_+_152020736 1.40 ENST00000509736.1
ENST00000505243.1
ENST00000514682.1
ENST00000322686.6
ENST00000503002.1
RPS3A
ribosomal protein S3A
chr19_+_13106383 1.36 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chrX_-_154563889 1.36 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr20_+_388791 1.34 ENST00000441733.1
ENST00000353660.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr5_-_93447333 1.33 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr7_-_41742697 1.33 ENST00000242208.4
INHBA
inhibin, beta A
chr4_+_142558078 1.33 ENST00000529613.1
IL15
interleukin 15
chr11_+_46402297 1.29 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr2_+_231280954 1.29 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr6_-_33281979 1.24 ENST00000426633.2
ENST00000467025.1
TAPBP
TAP binding protein (tapasin)
chr2_+_145780767 1.23 ENST00000599358.1
ENST00000596278.1
ENST00000596747.1
ENST00000608652.1
ENST00000609705.1
ENST00000608432.1
ENST00000596970.1
ENST00000602041.1
ENST00000601578.1
ENST00000596034.1
ENST00000414195.2
ENST00000594837.1
TEX41
testis expressed 41 (non-protein coding)
chr11_+_46402744 1.21 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr6_+_167525277 1.20 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr6_-_112575687 1.18 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr1_-_8483723 1.17 ENST00000476556.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr8_-_56986768 1.16 ENST00000523936.1
RPS20
ribosomal protein S20
chr4_+_142557771 1.14 ENST00000514653.1
IL15
interleukin 15
chr6_-_112575838 1.14 ENST00000455073.1
LAMA4
laminin, alpha 4
chr2_+_234545092 1.11 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr4_+_142557717 1.11 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr4_-_100140331 1.10 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr6_+_26156551 1.10 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr6_-_112575758 1.07 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr6_-_167276033 1.06 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_+_118869452 1.03 ENST00000357525.5
PLN
phospholamban
chr12_-_86650077 1.02 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_234590556 1.02 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr6_-_132910877 1.01 ENST00000258034.2
TAAR5
trace amine associated receptor 5
chr3_-_149375783 1.01 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr17_+_6659153 1.01 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr1_+_2985726 1.01 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr11_+_64008443 1.00 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chr18_-_47017956 0.99 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr16_-_3930724 0.98 ENST00000262367.5
CREBBP
CREB binding protein
chr11_+_64323428 0.98 ENST00000377581.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr8_-_29120580 0.98 ENST00000524189.1
KIF13B
kinesin family member 13B
chr5_-_64064508 0.98 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr6_+_152011628 0.95 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr11_+_64323156 0.95 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr3_+_69915385 0.95 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr14_-_23479331 0.92 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr12_+_9144626 0.92 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chrX_+_123095546 0.91 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr22_+_41697520 0.90 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr6_-_32806506 0.85 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr1_-_44497118 0.81 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_+_207262881 0.80 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr10_-_35104185 0.80 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr12_-_86650045 0.80 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_44497024 0.80 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_122526499 0.80 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr12_+_51318513 0.78 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr1_-_153919128 0.76 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr15_-_37393406 0.76 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr2_+_175260451 0.74 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chrX_-_106362013 0.73 ENST00000372487.1
ENST00000372479.3
ENST00000203616.8
RBM41
RNA binding motif protein 41
chr5_-_149380698 0.73 ENST00000296736.3
TIGD6
tigger transposable element derived 6
chr15_+_85144217 0.69 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr20_+_388935 0.69 ENST00000382181.2
ENST00000400247.3
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr5_+_112227311 0.68 ENST00000391338.1
ZRSR1
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr20_+_388679 0.66 ENST00000356286.5
ENST00000475269.1
RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr4_-_111558135 0.64 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr3_+_107241783 0.63 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr14_-_24615523 0.63 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr21_+_43933946 0.63 ENST00000352133.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr1_+_199996702 0.62 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr18_+_18943554 0.60 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr21_+_22370608 0.60 ENST00000400546.1
NCAM2
neural cell adhesion molecule 2
chr17_+_46908350 0.57 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr8_+_77593448 0.57 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr5_-_94417339 0.56 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_69240302 0.56 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr11_-_85338311 0.56 ENST00000376104.2
DLG2
discs, large homolog 2 (Drosophila)
chr17_+_74372662 0.54 ENST00000591651.1
ENST00000545180.1
SPHK1
sphingosine kinase 1
chr8_+_134203273 0.54 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr2_+_135676381 0.53 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2
cyclin T2
chr2_+_69240415 0.53 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr5_-_59481406 0.49 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_199996733 0.48 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr3_+_185046676 0.48 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr15_-_37392086 0.47 ENST00000561208.1
MEIS2
Meis homeobox 2
chr8_+_77593474 0.45 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr11_+_64323098 0.43 ENST00000301891.4
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr2_-_64246206 0.42 ENST00000409558.4
ENST00000272322.4
VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr13_-_95364389 0.38 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr12_+_94542459 0.36 ENST00000258526.4
PLXNC1
plexin C1
chr6_+_146348782 0.34 ENST00000361719.2
ENST00000392299.2
GRM1
glutamate receptor, metabotropic 1
chr3_-_46000064 0.30 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr3_-_168864427 0.30 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr20_+_6748311 0.30 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr2_+_234526272 0.28 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr15_+_71185148 0.22 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr5_+_140430979 0.22 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr16_+_10972818 0.20 ENST00000576601.1
CIITA
class II, major histocompatibility complex, transactivator
chr1_-_244006528 0.14 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr7_+_134832808 0.12 ENST00000275767.3
TMEM140
transmembrane protein 140
chr6_+_146348810 0.10 ENST00000492807.2
GRM1
glutamate receptor, metabotropic 1
chr19_-_6670128 0.07 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr6_-_121655552 0.07 ENST00000275159.6
TBC1D32
TBC1 domain family, member 32
chr22_-_30642782 0.07 ENST00000249075.3
LIF
leukemia inhibitory factor
chr6_-_10412600 0.06 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_167275991 0.06 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_145780739 0.05 ENST00000597173.1
ENST00000602108.1
ENST00000420472.1
TEX41
testis expressed 41 (non-protein coding)
chr10_+_22610124 0.04 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr7_+_134464414 0.04 ENST00000361901.2
CALD1
caldesmon 1
chr15_+_71184931 0.01 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr19_+_34287751 0.01 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr1_+_110453608 0.00 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.7 GO:1990108 protein linear deubiquitination(GO:1990108)
2.6 7.7 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
2.5 2.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
1.9 9.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.5 19.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.5 8.8 GO:0030421 defecation(GO:0030421)
1.2 3.6 GO:0045062 extrathymic T cell selection(GO:0045062)
1.1 4.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.1 4.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.1 4.2 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
1.0 4.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.9 7.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.9 8.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 11.7 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.7 2.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.7 2.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.6 5.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.6 2.4 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.5 1.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.5 1.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 5.0 GO:0006069 ethanol oxidation(GO:0006069)
0.5 1.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 1.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.4 1.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 4.0 GO:2001300 lipoxin metabolic process(GO:2001300)
0.4 2.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.4 1.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.4 41.7 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.4 2.7 GO:0008218 bioluminescence(GO:0008218)
0.4 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.4 1.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.3 1.0 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.3 8.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 2.7 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 7.2 GO:0035855 megakaryocyte development(GO:0035855)
0.3 1.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 2.3 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 1.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.3 2.4 GO:0015747 urate transport(GO:0015747)
0.3 3.7 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 1.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 2.2 GO:0051552 flavone metabolic process(GO:0051552)
0.2 0.6 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.9 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 0.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.9 GO:1901098 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1 4.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.1 1.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.8 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:0019086 late viral transcription(GO:0019086)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.1 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 1.4 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 4.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.0 GO:0060523 prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 2.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 5.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.8 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 5.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 3.1 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 1.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 4.2 GO:0000910 cytokinesis(GO:0000910)
0.0 0.2 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.2 GO:0008542 visual learning(GO:0008542)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 2.8 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 5.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 29.7 GO:1990111 spermatoproteasome complex(GO:1990111)
2.6 15.5 GO:0008537 proteasome activator complex(GO:0008537)
2.5 7.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
2.0 8.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.4 8.4 GO:0042825 TAP complex(GO:0042825)
0.8 2.4 GO:0005588 collagen type V trimer(GO:0005588)
0.8 2.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.7 2.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 4.2 GO:0030870 Mre11 complex(GO:0030870)
0.5 2.7 GO:0071797 LUBAC complex(GO:0071797)
0.4 1.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.4 1.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 14.7 GO:0097542 ciliary tip(GO:0097542)
0.2 1.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 5.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 5.5 GO:0005605 basal lamina(GO:0005605)
0.1 2.5 GO:0042599 lamellar body(GO:0042599)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 1.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.0 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:0000938 GARP complex(GO:0000938)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 5.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 11.7 GO:0030426 growth cone(GO:0030426)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 4.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 7.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 8.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 7.2 GO:0016607 nuclear speck(GO:0016607)
0.0 6.2 GO:0016604 nuclear body(GO:0016604)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 4.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.5 GO:0061133 endopeptidase activator activity(GO:0061133)
2.1 8.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
1.5 7.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.5 14.7 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
1.3 4.0 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.0 3.9 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.9 26.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 5.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 5.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.7 4.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 4.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.5 8.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.5 2.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.4 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 1.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.4 7.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 5.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 1.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 2.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 7.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 0.6 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 1.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 9.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 4.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.9 GO:0048273 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 4.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.0 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 3.6 GO:0008009 chemokine activity(GO:0008009)
0.1 2.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.9 GO:0070628 proteasome binding(GO:0070628)
0.1 1.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.7 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.5 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 8.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 2.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 5.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 5.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 4.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 9.3 GO:0008201 heparin binding(GO:0008201)
0.0 13.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 2.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.0 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 8.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 14.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 4.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 4.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 11.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 7.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 6.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 2.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 8.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 41.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.5 4.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.4 19.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 7.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 2.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 6.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 10.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 4.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 4.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 5.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 8.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 4.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events