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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for RARA

Z-value: 0.15

Motif logo

Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
ENSG00000131759.13 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg19_v2_chr17_+_38474489_38474548-0.046.0e-01Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_54378923 8.48 ENST00000303460.4
homeobox C10
chr4_+_107236692 7.31 ENST00000510207.1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr13_+_43597269 7.21 ENST00000379221.2
DnaJ (Hsp40) homolog, subfamily C, member 15
chr16_-_11680791 6.37 ENST00000571976.1
ENST00000413364.2
lipopolysaccharide-induced TNF factor
chr10_+_17270214 6.16 ENST00000544301.1
vimentin
chr10_+_115438920 5.72 ENST00000429617.1
ENST00000369331.4
caspase 7, apoptosis-related cysteine peptidase
chr5_+_65440032 5.47 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_53704157 4.71 ENST00000371466.4
ENST00000371470.3
mago-nashi homolog, proliferation-associated (Drosophila)
chr16_-_11680759 4.64 ENST00000571459.1
ENST00000570798.1
ENST00000572255.1
ENST00000574763.1
ENST00000574703.1
ENST00000571277.1
ENST00000381810.3
lipopolysaccharide-induced TNF factor
chr4_+_107236847 4.52 ENST00000358008.3
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr4_+_107236722 4.42 ENST00000442366.1
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr11_-_102323489 4.28 ENST00000361236.3
transmembrane protein 123
chr19_+_16435625 4.23 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr1_+_165796753 4.21 ENST00000367879.4
uridine-cytidine kinase 2
chr3_+_133293278 4.16 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr2_-_151344172 4.10 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr22_+_45072925 4.09 ENST00000006251.7
proline rich 5 (renal)
chr1_-_3816779 4.06 ENST00000361605.3
chromosome 1 open reading frame 174
chr22_+_45072958 4.01 ENST00000403581.1
proline rich 5 (renal)
chr9_-_21995300 3.98 ENST00000498628.2
cyclin-dependent kinase inhibitor 2A
chr3_-_185641681 3.97 ENST00000259043.7
transformer 2 beta homolog (Drosophila)
chr7_-_45960850 3.79 ENST00000381083.4
ENST00000381086.5
ENST00000275521.6
insulin-like growth factor binding protein 3
chr1_-_16939976 3.73 ENST00000430580.2
neuroblastoma breakpoint family, member 1
chr11_+_32605350 3.73 ENST00000531120.1
ENST00000524896.1
ENST00000323213.5
eukaryotic translation initiation factor 3, subunit M
chr12_+_104324112 3.69 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr6_-_74233480 3.67 ENST00000455918.1
eukaryotic translation elongation factor 1 alpha 1
chr10_+_43633914 3.66 ENST00000374466.3
ENST00000374464.1
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr6_-_35888905 3.52 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr3_-_55521323 3.49 ENST00000264634.4
wingless-type MMTV integration site family, member 5A
chr15_+_90777424 3.43 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr9_-_21994597 3.42 ENST00000579755.1
cyclin-dependent kinase inhibitor 2A
chr9_-_21994344 3.38 ENST00000530628.2
ENST00000361570.3
cyclin-dependent kinase inhibitor 2A
chr1_+_145439306 3.37 ENST00000425134.1
thioredoxin interacting protein
chr11_+_114310237 3.36 ENST00000539119.1
RNA exonuclease 2
chr7_-_105752971 3.22 ENST00000011473.2
synaptophysin-like 1
chr3_+_133292574 3.15 ENST00000264993.3
CDV3 homolog (mouse)
chr1_-_93426998 3.14 ENST00000370310.4
family with sequence similarity 69, member A
chr22_+_50624323 3.12 ENST00000380909.4
ENST00000303434.4
TraB domain containing
chr19_-_4540486 3.08 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr11_+_9482551 3.08 ENST00000438144.2
ENST00000526657.1
ENST00000299606.2
ENST00000534265.1
ENST00000412390.2
zinc finger protein 143
chr11_+_114310164 3.01 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
RNA exonuclease 2
chr4_-_87855851 2.98 ENST00000473559.1
chromosome 4 open reading frame 36
chr13_+_25670268 2.97 ENST00000281589.3
poly(A) binding protein, cytoplasmic 3
chr7_+_148395733 2.91 ENST00000602748.1
cullin 1
chr1_+_25870070 2.89 ENST00000374338.4
low density lipoprotein receptor adaptor protein 1
chr20_-_34330129 2.89 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr5_-_114961858 2.88 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr6_-_31324943 2.82 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr18_-_812231 2.80 ENST00000314574.4
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr5_+_118690466 2.75 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr1_+_203764742 2.74 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
zinc finger CCCH-type containing 11A
chr7_-_105752651 2.69 ENST00000470347.1
ENST00000455385.2
synaptophysin-like 1
chr11_+_58910201 2.65 ENST00000528737.1
family with sequence similarity 111, member A
chr11_-_46142615 2.62 ENST00000529734.1
ENST00000323180.6
PHD finger protein 21A
chr17_+_7476136 2.58 ENST00000582169.1
ENST00000578754.1
ENST00000578495.1
ENST00000293831.8
ENST00000380512.5
ENST00000585024.1
ENST00000583802.1
ENST00000577269.1
ENST00000584784.1
ENST00000582746.1
eukaryotic translation initiation factor 4A1
chr15_+_23255242 2.53 ENST00000450802.3
golgin A8 family, member I
chr7_+_148395959 2.46 ENST00000325222.4
cullin 1
chr19_-_12405689 2.45 ENST00000355684.5
zinc finger protein 44
chr22_-_29138386 2.43 ENST00000544772.1
checkpoint kinase 2
chr7_+_130794846 2.35 ENST00000421797.2
muskelin 1, intracellular mediator containing kelch motifs
chr18_+_12948000 2.32 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1-like (S. cerevisiae)
chr9_-_88969303 2.30 ENST00000277141.6
ENST00000375963.3
zinc finger, CCHC domain containing 6
chr5_-_157286104 2.29 ENST00000530742.1
ENST00000523908.1
ENST00000523094.1
ENST00000296951.5
ENST00000411809.2
clathrin interactor 1
chr10_+_60144782 2.29 ENST00000487519.1
transcription factor A, mitochondrial
chr15_+_80351977 2.29 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr11_+_10326612 2.29 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
adrenomedullin
chr16_-_425205 2.27 ENST00000448854.1
transmembrane protein 8A
chr5_+_138609441 2.24 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr11_+_101983176 2.22 ENST00000524575.1
Yes-associated protein 1
chrX_+_69509927 2.21 ENST00000374403.3
kinesin family member 4A
chr22_+_24951436 2.19 ENST00000215829.3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr3_-_142608001 2.18 ENST00000295992.3
procollagen C-endopeptidase enhancer 2
chr22_-_32058166 2.18 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr15_-_63448973 2.17 ENST00000462430.1
ribosomal protein S27-like
chr2_+_189157498 2.15 ENST00000359135.3
GULP, engulfment adaptor PTB domain containing 1
chr9_+_114393634 2.13 ENST00000556107.1
ENST00000374294.3
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr18_-_812517 2.12 ENST00000584307.1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr10_+_62538089 2.12 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
cyclin-dependent kinase 1
chr18_+_19749386 2.11 ENST00000269216.3
GATA binding protein 6
chr1_-_43855444 2.09 ENST00000372455.4
mediator complex subunit 8
chr11_-_18610275 2.09 ENST00000543987.1
UEV and lactate/malate dehyrogenase domains
chr22_-_29137771 2.08 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr9_-_88969339 2.07 ENST00000375960.2
ENST00000375961.2
zinc finger, CCHC domain containing 6
chr8_+_70404996 2.06 ENST00000402687.4
ENST00000419716.3
sulfatase 1
chr9_-_135230336 2.05 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
senataxin
chr14_-_71107921 2.04 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr8_-_101348408 2.02 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr10_+_60145155 2.02 ENST00000373895.3
transcription factor A, mitochondrial
chr6_-_41040195 2.00 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
O-acyl-ADP-ribose deacylase 1
chr2_+_189157536 2.00 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr14_-_78227476 1.99 ENST00000554775.1
ENST00000555761.1
ENST00000554324.1
ENST00000261531.7
SNW domain containing 1
chr14_-_90085458 1.98 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr14_+_24605389 1.98 ENST00000382708.3
ENST00000561435.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr13_+_53029564 1.98 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
cytoskeleton associated protein 2
chr10_-_103880209 1.96 ENST00000425280.1
LIM domain binding 1
chr1_-_33168336 1.95 ENST00000373484.3
syncoilin, intermediate filament protein
chr18_+_12947981 1.95 ENST00000262124.11
SEH1-like (S. cerevisiae)
chr10_-_135090360 1.93 ENST00000486609.1
ENST00000445355.3
ENST00000485491.2
ADAM metallopeptidase domain 8
chr11_-_18610214 1.93 ENST00000300038.7
ENST00000396197.3
ENST00000320750.6
UEV and lactate/malate dehyrogenase domains
chr3_-_142607740 1.92 ENST00000485766.1
procollagen C-endopeptidase enhancer 2
chr5_+_31532373 1.92 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr12_+_51632638 1.91 ENST00000549732.2
DAZ associated protein 2
chr21_-_46707793 1.88 ENST00000331343.7
ENST00000349485.5
protein O-fucosyltransferase 2
chr10_+_70715884 1.87 ENST00000354185.4
DEAD (Asp-Glu-Ala-Asp) box helicase 21
chr14_-_75536182 1.85 ENST00000555463.1
acylphosphatase 1, erythrocyte (common) type
chr21_+_35445827 1.84 ENST00000608209.1
ENST00000381151.3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr9_-_139891165 1.84 ENST00000494426.1
chloride intracellular channel 3
chr13_+_53030107 1.84 ENST00000490903.1
ENST00000480747.1
cytoskeleton associated protein 2
chr1_+_32687971 1.82 ENST00000373586.1
eukaryotic translation initiation factor 3, subunit I
chr1_+_109289279 1.81 ENST00000370008.3
syntaxin binding protein 3
chr9_-_132597529 1.81 ENST00000372447.3
chromosome 9 open reading frame 78
chr9_-_21995249 1.80 ENST00000494262.1
cyclin-dependent kinase inhibitor 2A
chr17_-_80291818 1.79 ENST00000269389.3
ENST00000581691.1
secreted and transmembrane 1
chr10_+_62538248 1.79 ENST00000448257.2
cyclin-dependent kinase 1
chr3_+_127317066 1.77 ENST00000265056.7
minichromosome maintenance complex component 2
chr15_+_28623784 1.76 ENST00000526619.2
ENST00000337838.7
ENST00000532622.2
golgin A8 family, member F
chr10_-_135090338 1.75 ENST00000415217.3
ADAM metallopeptidase domain 8
chr17_+_7210898 1.74 ENST00000572815.1
eukaryotic translation initiation factor 5A
chr1_-_211848899 1.72 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NIMA-related kinase 2
chr5_-_31532160 1.72 ENST00000511367.2
ENST00000513349.1
drosha, ribonuclease type III
chr11_-_65430554 1.69 ENST00000308639.9
ENST00000406246.3
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr8_+_87354945 1.67 ENST00000517970.1
WW domain containing E3 ubiquitin protein ligase 1
chr15_-_37393406 1.65 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr13_+_73356197 1.65 ENST00000326291.6
progesterone immunomodulatory binding factor 1
chr16_+_56995762 1.64 ENST00000200676.3
ENST00000379780.2
cholesteryl ester transfer protein, plasma
chr1_+_26606608 1.64 ENST00000319041.6
SH3 domain binding glutamic acid-rich protein like 3
chr6_+_111195973 1.61 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
adenosylmethionine decarboxylase 1
chr19_-_19739007 1.60 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
lysophosphatidic acid receptor 2
chr3_-_126194707 1.60 ENST00000336332.5
ENST00000389709.3
ZXD family zinc finger C
chr12_+_22778116 1.58 ENST00000538218.1
ethanolamine kinase 1
chrX_-_37706815 1.57 ENST00000378578.4
dynein, light chain, Tctex-type 3
chr7_-_55640176 1.57 ENST00000285279.5
vesicular, overexpressed in cancer, prosurvival protein 1
chr2_+_101179152 1.55 ENST00000264254.6
phosducin-like 3
chr16_+_577697 1.55 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
calpain 15
chr4_+_38665810 1.54 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr6_-_127664736 1.53 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
enoyl CoA hydratase domain containing 1
chr1_+_23037323 1.51 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPH receptor B2
chr22_+_29664248 1.50 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWS RNA-binding protein 1
chr1_+_76251879 1.50 ENST00000535300.1
ENST00000319942.3
Rab geranylgeranyltransferase, beta subunit
chr5_-_137911049 1.49 ENST00000297185.3
heat shock 70kDa protein 9 (mortalin)
chr5_-_79950371 1.47 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
dihydrofolate reductase
chr16_+_31885079 1.46 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr14_-_91526462 1.45 ENST00000536315.2
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr6_-_127664683 1.45 ENST00000528402.1
ENST00000454591.2
enoyl CoA hydratase domain containing 1
chr6_-_41040268 1.44 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
O-acyl-ADP-ribose deacylase 1
chr10_-_126849588 1.43 ENST00000411419.2
C-terminal binding protein 2
chr1_-_156786530 1.41 ENST00000368198.3
SH2 domain containing 2A
chr6_+_96025341 1.41 ENST00000369293.1
ENST00000358812.4
mannosidase, endo-alpha
chr13_+_98612446 1.40 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
importin 5
chr6_+_32709119 1.40 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr22_+_50312379 1.37 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chr1_-_113498943 1.35 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr22_+_50312316 1.33 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr2_+_47630255 1.33 ENST00000406134.1
mutS homolog 2
chr2_-_40006357 1.33 ENST00000505747.1
THUMP domain containing 2
chr11_-_18610246 1.33 ENST00000379387.4
ENST00000541984.1
UEV and lactate/malate dehyrogenase domains
chr1_+_215256467 1.32 ENST00000391894.2
ENST00000444842.2
potassium channel, subfamily K, member 2
chr5_+_139781393 1.32 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ankyrin repeat and KH domain containing 1
chr2_+_108443388 1.31 ENST00000354986.4
ENST00000408999.3
RANBP2-like and GRIP domain containing 4
chr2_-_235405679 1.30 ENST00000390645.2
ADP-ribosylation factor-like 4C
chr16_-_15188106 1.29 ENST00000429751.2
ENST00000564131.1
ENST00000563559.1
ENST00000198767.6
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_-_113498616 1.28 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr11_-_8986474 1.28 ENST00000525069.1
TMEM9 domain family, member B
chr11_-_65325430 1.26 ENST00000322147.4
latent transforming growth factor beta binding protein 3
chr12_+_67663056 1.26 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr5_+_112312416 1.26 ENST00000389063.2
decapping mRNA 2
chr11_+_59480899 1.24 ENST00000300150.7
syntaxin 3
chr15_+_49462434 1.24 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
galactokinase 2
chr5_-_146781153 1.24 ENST00000520473.1
dihydropyrimidinase-like 3
chr9_+_21802542 1.23 ENST00000380172.4
methylthioadenosine phosphorylase
chrX_+_100878079 1.23 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr15_-_74374891 1.23 ENST00000290438.3
golgin A6 family, member A
chr15_+_33010175 1.22 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr19_-_12405606 1.22 ENST00000356109.5
zinc finger protein 44
chr11_+_105948216 1.20 ENST00000278618.4
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr3_-_52486841 1.20 ENST00000496590.1
troponin C type 1 (slow)
chr19_-_16770915 1.20 ENST00000593459.1
ENST00000358726.6
ENST00000597711.1
ENST00000487416.2
Small integral membrane protein 7; Uncharacterized protein
small integral membrane protein 7
chr10_-_112678692 1.19 ENST00000605742.1
BBSome interacting protein 1
chr10_-_112678904 1.19 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr2_+_209130965 1.19 ENST00000392202.3
ENST00000264380.4
ENST00000407449.1
ENST00000308862.6
phosphoinositide kinase, FYVE finger containing
chr16_+_29674277 1.18 ENST00000395389.2
sialophorin
chr17_+_57784826 1.18 ENST00000262291.4
vacuole membrane protein 1
chr1_-_156786634 1.18 ENST00000392306.2
ENST00000368199.3
SH2 domain containing 2A
chr3_+_157827841 1.17 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
arginine/serine-rich coiled-coil 1
chr1_-_111506562 1.17 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr6_-_127664475 1.17 ENST00000474289.2
ENST00000534442.1
ENST00000368289.2
ENST00000525745.1
ENST00000430841.2
enoyl CoA hydratase domain containing 1
chr6_+_32006159 1.16 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr6_+_36097992 1.16 ENST00000211287.4
mitogen-activated protein kinase 13
chr14_-_64194745 1.16 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr22_-_31328881 1.15 ENST00000445980.1
MORC family CW-type zinc finger 2
chr2_-_113594279 1.15 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr11_+_44117741 1.14 ENST00000395673.3
ENST00000343631.3
exostosin glycosyltransferase 2
chr5_+_140019004 1.14 ENST00000394671.3
ENST00000511410.1
ENST00000537378.1
transmembrane and coiled-coil domains 6
chr10_-_43892668 1.14 ENST00000544000.1
heterogeneous nuclear ribonucleoprotein F
chr19_+_55105085 1.14 ENST00000251372.3
ENST00000453777.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr2_+_47630108 1.13 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
mutS homolog 2
chr12_+_22778009 1.12 ENST00000266517.4
ENST00000335148.3
ethanolamine kinase 1
chr6_+_32006042 1.11 ENST00000418967.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr4_-_2936514 1.11 ENST00000508221.1
ENST00000507555.1
ENST00000355443.4
major facilitator superfamily domain containing 10
chr14_-_105262055 1.08 ENST00000349310.3
v-akt murine thymoma viral oncogene homolog 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.4 4.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.2 13.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
1.2 3.7 GO:2000412 activation of MAPK activity involved in innate immune response(GO:0035419) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) positive regulation of thymocyte migration(GO:2000412)
1.2 3.5 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
1.1 4.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.1 4.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
1.0 4.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.9 8.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.9 5.6 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.9 3.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.7 8.1 GO:0038203 TORC2 signaling(GO:0038203)
0.7 1.4 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.7 2.9 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.7 5.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7 2.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.7 6.6 GO:0010265 SCF complex assembly(GO:0010265)
0.7 2.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.7 3.9 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.6 1.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6 6.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.5 1.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 2.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 1.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.5 2.5 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.5 2.0 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.5 2.9 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.5 2.3 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.4 1.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.4 1.2 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.4 1.2 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 3.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 2.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.4 1.9 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.4 1.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.4 1.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.4 18.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.4 3.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.3 4.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.3 1.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.3 1.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.3 5.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.3 1.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.3 3.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 0.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 0.6 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.3 1.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.3 1.2 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.3 1.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.3 0.9 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.3 0.9 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.3 2.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3 4.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 9.8 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.3 3.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 1.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2 0.7 GO:0051697 protein delipidation(GO:0051697)
0.2 2.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 1.7 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.2 1.0 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 0.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.2 0.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.2 2.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 0.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 1.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 1.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 3.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 7.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.0 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.2 1.8 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.2 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 1.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 1.8 GO:0015791 polyol transport(GO:0015791)
0.2 2.7 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.2 10.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 1.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 3.4 GO:0002347 response to tumor cell(GO:0002347)
0.2 4.9 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.2 0.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.2 0.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 2.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.2 0.8 GO:0061205 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 0.9 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.6 GO:0035803 egg coat formation(GO:0035803)
0.1 2.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.6 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1 2.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.2 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 1.7 GO:0051823 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of synapse structural plasticity(GO:0051823)
0.1 0.4 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 2.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.9 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) protein localization to adherens junction(GO:0071896)
0.1 2.2 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.6 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 2.4 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 2.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.8 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 3.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 3.0 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 4.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.5 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.8 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 1.5 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 1.6 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.2 GO:0042220 response to cocaine(GO:0042220)
0.1 0.5 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 2.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.0 GO:0002021 response to dietary excess(GO:0002021)
0.1 1.2 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0019532 oxalate transport(GO:0019532)
0.1 1.0 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.2 GO:0032288 myelin assembly(GO:0032288)
0.0 1.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.7 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 1.7 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) histone H4-R3 methylation(GO:0043985)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.0 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.0 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 4.0 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.8 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 2.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.2 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 2.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 1.1 GO:0015893 drug transport(GO:0015893)
0.0 1.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 2.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 2.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 2.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.7 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 3.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 1.4 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.6 GO:0006260 DNA replication(GO:0006260)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.6 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 2.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 2.3 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0042699 primary ovarian follicle growth(GO:0001545) follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0007140 male meiosis(GO:0007140)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.6 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 1.3 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.3 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
1.8 11.0 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.2 13.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.2 3.7 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.9 8.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.8 2.5 GO:0032302 MutSbeta complex(GO:0032302)
0.8 3.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.8 5.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 5.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.6 3.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.6 4.1 GO:0061700 GATOR2 complex(GO:0061700)
0.6 1.7 GO:0071159 NF-kappaB complex(GO:0071159)
0.5 3.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 8.1 GO:0031932 TORC2 complex(GO:0031932)
0.4 2.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 3.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 6.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 3.1 GO:0034464 BBSome(GO:0034464)
0.3 2.0 GO:0008537 proteasome activator complex(GO:0008537)
0.3 1.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.3 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 2.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 1.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.3 2.2 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.3 2.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 4.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 2.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.6 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 1.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 2.7 GO:0000346 transcription export complex(GO:0000346)
0.2 1.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 1.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.2 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.7 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 3.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 9.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.0 GO:0097255 R2TP complex(GO:0097255)
0.1 5.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 1.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 4.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 16.7 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.7 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0032433 filopodium tip(GO:0032433)
0.1 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 7.1 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.3 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 1.6 GO:0043234 protein complex(GO:0043234)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 2.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0012505 endomembrane system(GO:0012505)
0.0 0.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 3.9 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.4 GO:0042581 specific granule(GO:0042581)
0.0 2.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 1.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
1.4 4.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
1.1 4.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
1.0 6.2 GO:1990254 keratin filament binding(GO:1990254)
0.9 4.3 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.8 2.5 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.8 2.3 GO:0017129 triglyceride binding(GO:0017129)
0.7 3.7 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.7 2.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.7 2.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.7 2.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.6 4.2 GO:0004849 uridine kinase activity(GO:0004849)
0.6 10.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5 3.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 1.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.4 4.7 GO:0004645 phosphorylase activity(GO:0004645)
0.4 19.9 GO:0000049 tRNA binding(GO:0000049)
0.3 1.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.0 GO:0004802 transketolase activity(GO:0004802)
0.3 1.7 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 3.7 GO:0046790 virion binding(GO:0046790)
0.3 1.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.3 0.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 1.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 0.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 2.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.3 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 12.9 GO:0050699 WW domain binding(GO:0050699)
0.3 1.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3 0.9 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 0.9 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.3 2.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 2.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3 1.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.3 1.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 1.5 GO:0051870 methotrexate binding(GO:0051870)
0.2 1.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.8 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 0.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 8.9 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.2 1.2 GO:0050542 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.2 4.7 GO:0048018 receptor agonist activity(GO:0048018)
0.2 1.2 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.2 2.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 2.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 6.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.2 0.6 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 5.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 1.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 2.2 GO:0008494 translation activator activity(GO:0008494)
0.2 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 1.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 1.0 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 1.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.4 GO:0004769 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.1 1.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 6.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.6 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.9 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 2.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.1 GO:0019534 toxin transporter activity(GO:0019534)
0.1 1.2 GO:0031013 troponin I binding(GO:0031013)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.8 GO:0019863 IgE binding(GO:0019863)
0.1 0.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 1.9 GO:0032794 nitric-oxide synthase regulator activity(GO:0030235) GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 4.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 4.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 3.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 3.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 4.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.6 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 3.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.7 GO:0016918 retinal binding(GO:0016918)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.4 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 2.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036) bioactive lipid receptor activity(GO:0045125)
0.0 0.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 3.9 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 1.6 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 12.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 8.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 3.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 4.8 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 1.2 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 3.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 7.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 5.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 5.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 12.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 5.7 PID IL1 PATHWAY IL1-mediated signaling events
0.1 7.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 5.4 PID AURORA B PATHWAY Aurora B signaling
0.1 4.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 11.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 ST GAQ PATHWAY G alpha q Pathway
0.0 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 5.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 8.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 12.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 3.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 2.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 18.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 2.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 4.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 1.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 1.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 6.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 3.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 9.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 3.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 4.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 3.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 2.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.4 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 3.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.2 REACTOME KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 4.3 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 4.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.4 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.2 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 2.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 6.7 REACTOME TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.8 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins