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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for RARB
Z-value: 0.72
Motif logo
Transcription factors associated with RARB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RARB
|
ENSG00000077092.14 | retinoic acid receptor beta |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RARB | hg19_v2_chr3_+_25469724_25469773 | 0.50 | 2.0e-15 | Click! |
Activity profile of RARB motif
Sorted Z-values of RARB motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_17721920 | 28.49 |
ENST00000295156.4
|
VSNL1
|
visinin-like 1 |
| chr11_-_111782696 | 26.89 |
ENST00000227251.3
ENST00000526180.1 |
CRYAB
|
crystallin, alpha B |
| chr17_-_26903900 | 25.75 |
ENST00000395319.3
ENST00000581807.1 ENST00000584086.1 ENST00000395321.2 |
ALDOC
|
aldolase C, fructose-bisphosphate |
| chr11_-_111782484 | 22.00 |
ENST00000533971.1
|
CRYAB
|
crystallin, alpha B |
| chr19_-_9731872 | 18.39 |
ENST00000424629.1
ENST00000326044.5 ENST00000354661.4 ENST00000435550.1 ENST00000444611.1 ENST00000421525.1 |
ZNF561
|
zinc finger protein 561 |
| chr8_-_27462822 | 17.77 |
ENST00000522098.1
|
CLU
|
clusterin |
| chr16_+_15596123 | 12.28 |
ENST00000452191.2
|
C16orf45
|
chromosome 16 open reading frame 45 |
| chr3_-_122283100 | 10.21 |
ENST00000492382.1
ENST00000462315.1 |
PARP9
|
poly (ADP-ribose) polymerase family, member 9 |
| chr4_-_84406218 | 9.66 |
ENST00000515303.1
|
FAM175A
|
family with sequence similarity 175, member A |
| chr16_-_4852915 | 9.56 |
ENST00000322048.7
|
ROGDI
|
rogdi homolog (Drosophila) |
| chr2_+_220492116 | 9.05 |
ENST00000373760.2
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3 |
| chr18_-_21852143 | 8.95 |
ENST00000399443.3
|
OSBPL1A
|
oxysterol binding protein-like 1A |
| chr7_+_20686946 | 8.54 |
ENST00000443026.2
ENST00000406935.1 |
ABCB5
|
ATP-binding cassette, sub-family B (MDR/TAP), member 5 |
| chr8_+_84824920 | 8.41 |
ENST00000523678.1
|
RP11-120I21.2
|
RP11-120I21.2 |
| chr2_-_152830441 | 8.33 |
ENST00000534999.1
ENST00000397327.2 |
CACNB4
|
calcium channel, voltage-dependent, beta 4 subunit |
| chr6_-_28367510 | 8.33 |
ENST00000361028.1
|
ZSCAN12
|
zinc finger and SCAN domain containing 12 |
| chr6_-_52859046 | 8.08 |
ENST00000457564.1
ENST00000541324.1 ENST00000370960.1 |
GSTA4
|
glutathione S-transferase alpha 4 |
| chr1_+_160175201 | 7.98 |
ENST00000368076.1
|
PEA15
|
phosphoprotein enriched in astrocytes 15 |
| chr2_+_113342163 | 7.92 |
ENST00000409719.1
|
CHCHD5
|
coiled-coil-helix-coiled-coil-helix domain containing 5 |
| chr2_-_152830479 | 7.91 |
ENST00000360283.6
|
CACNB4
|
calcium channel, voltage-dependent, beta 4 subunit |
| chr19_+_57791419 | 7.72 |
ENST00000537645.1
|
ZNF460
|
zinc finger protein 460 |
| chr6_+_31554636 | 7.62 |
ENST00000433492.1
|
LST1
|
leukocyte specific transcript 1 |
| chr11_+_121447469 | 7.56 |
ENST00000532694.1
ENST00000534286.1 |
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing |
| chr20_-_43729750 | 7.51 |
ENST00000537075.1
ENST00000306117.1 |
KCNS1
|
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 |
| chr1_+_78245303 | 7.47 |
ENST00000370791.3
ENST00000443751.2 |
FAM73A
|
family with sequence similarity 73, member A |
| chr17_-_7518145 | 7.36 |
ENST00000250113.7
ENST00000571597.1 |
FXR2
|
fragile X mental retardation, autosomal homolog 2 |
| chr11_+_61520075 | 7.30 |
ENST00000278836.5
|
MYRF
|
myelin regulatory factor |
| chr1_+_160175117 | 7.19 |
ENST00000360472.4
|
PEA15
|
phosphoprotein enriched in astrocytes 15 |
| chr11_-_63381925 | 7.05 |
ENST00000415826.1
|
PLA2G16
|
phospholipase A2, group XVI |
| chr2_+_131769256 | 6.95 |
ENST00000355771.3
|
ARHGEF4
|
Rho guanine nucleotide exchange factor (GEF) 4 |
| chr2_-_21266935 | 6.88 |
ENST00000233242.1
|
APOB
|
apolipoprotein B |
| chr7_-_56160625 | 6.86 |
ENST00000446428.1
ENST00000432123.1 ENST00000452681.2 ENST00000537360.1 |
PHKG1
|
phosphorylase kinase, gamma 1 (muscle) |
| chr11_+_63870660 | 6.75 |
ENST00000246841.3
|
FLRT1
|
fibronectin leucine rich transmembrane protein 1 |
| chr3_-_47554791 | 6.57 |
ENST00000449409.1
ENST00000414236.1 ENST00000444760.1 ENST00000439305.1 |
ELP6
|
elongator acetyltransferase complex subunit 6 |
| chr1_+_9005917 | 6.57 |
ENST00000549778.1
ENST00000480186.3 ENST00000377443.2 ENST00000377436.3 ENST00000377442.2 |
CA6
|
carbonic anhydrase VI |
| chr22_+_21336267 | 6.54 |
ENST00000215739.8
|
LZTR1
|
leucine-zipper-like transcription regulator 1 |
| chr6_+_31554612 | 6.53 |
ENST00000211921.7
|
LST1
|
leukocyte specific transcript 1 |
| chr2_-_176866978 | 6.41 |
ENST00000392540.2
ENST00000409660.1 ENST00000544803.1 ENST00000272748.4 |
KIAA1715
|
KIAA1715 |
| chr15_-_90892669 | 6.33 |
ENST00000412799.2
|
GABARAPL3
|
GABA(A) receptors associated protein like 3, pseudogene |
| chrX_+_73164149 | 6.28 |
ENST00000602938.1
ENST00000602294.1 ENST00000602920.1 ENST00000602737.1 ENST00000602772.1 |
JPX
|
JPX transcript, XIST activator (non-protein coding) |
| chr1_-_23520755 | 6.27 |
ENST00000314113.3
|
HTR1D
|
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| chr11_-_63381823 | 6.06 |
ENST00000323646.5
|
PLA2G16
|
phospholipase A2, group XVI |
| chr14_+_95078714 | 6.03 |
ENST00000393078.3
ENST00000393080.4 ENST00000467132.1 |
SERPINA3
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| chr19_+_39881951 | 5.82 |
ENST00000315588.5
ENST00000594368.1 ENST00000599213.2 ENST00000596297.1 |
MED29
|
mediator complex subunit 29 |
| chr3_+_49297518 | 5.76 |
ENST00000440528.3
|
RP11-3B7.1
|
Uncharacterized protein |
| chrX_-_14047996 | 5.72 |
ENST00000380523.4
ENST00000398355.3 |
GEMIN8
|
gem (nuclear organelle) associated protein 8 |
| chr1_+_16330723 | 5.65 |
ENST00000329454.2
|
C1orf64
|
chromosome 1 open reading frame 64 |
| chr2_+_217082311 | 5.36 |
ENST00000597904.1
|
RP11-566E18.3
|
RP11-566E18.3 |
| chr4_+_8594435 | 5.33 |
ENST00000382480.2
|
CPZ
|
carboxypeptidase Z |
| chr3_+_184058125 | 5.21 |
ENST00000310585.4
|
FAM131A
|
family with sequence similarity 131, member A |
| chr7_-_44180884 | 5.15 |
ENST00000458240.1
ENST00000223364.3 |
MYL7
|
myosin, light chain 7, regulatory |
| chrY_-_23548246 | 5.10 |
ENST00000382764.1
|
CYorf17
|
chromosome Y open reading frame 17 |
| chr17_+_41363854 | 5.02 |
ENST00000588693.1
ENST00000588659.1 ENST00000541594.1 ENST00000536052.1 ENST00000331615.3 |
TMEM106A
|
transmembrane protein 106A |
| chr17_-_6338399 | 4.93 |
ENST00000570584.1
ENST00000574913.1 ENST00000571740.1 ENST00000575265.1 ENST00000574506.1 |
AIPL1
|
aryl hydrocarbon receptor interacting protein-like 1 |
| chr15_+_90808919 | 4.91 |
ENST00000379095.3
|
NGRN
|
neugrin, neurite outgrowth associated |
| chr1_-_23521222 | 4.86 |
ENST00000374619.1
|
HTR1D
|
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| chr1_+_43803475 | 4.83 |
ENST00000372470.3
ENST00000413998.2 |
MPL
|
myeloproliferative leukemia virus oncogene |
| chr11_+_111783450 | 4.79 |
ENST00000537382.1
|
HSPB2
|
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA. |
| chr11_+_118938485 | 4.77 |
ENST00000300793.6
|
VPS11
|
vacuolar protein sorting 11 homolog (S. cerevisiae) |
| chr4_+_8594364 | 4.76 |
ENST00000360986.4
|
CPZ
|
carboxypeptidase Z |
| chr4_-_100140331 | 4.70 |
ENST00000407820.2
ENST00000394897.1 ENST00000508558.1 ENST00000394899.2 |
ADH6
|
alcohol dehydrogenase 6 (class V) |
| chr11_-_1587166 | 4.58 |
ENST00000331588.4
|
DUSP8
|
dual specificity phosphatase 8 |
| chr19_-_15344243 | 4.57 |
ENST00000602233.1
|
EPHX3
|
epoxide hydrolase 3 |
| chr6_-_31763408 | 4.49 |
ENST00000444930.2
|
VARS
|
valyl-tRNA synthetase |
| chr12_+_57943781 | 4.40 |
ENST00000455537.2
ENST00000286452.5 |
KIF5A
|
kinesin family member 5A |
| chr19_-_41256207 | 4.40 |
ENST00000598485.2
ENST00000470681.1 ENST00000339153.3 ENST00000598729.1 |
C19orf54
|
chromosome 19 open reading frame 54 |
| chr1_-_109618566 | 4.40 |
ENST00000338366.5
|
TAF13
|
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| chr16_-_20587599 | 4.40 |
ENST00000566384.1
ENST00000565232.1 ENST00000567001.1 ENST00000565322.1 ENST00000569344.1 ENST00000329697.6 ENST00000414188.2 ENST00000568882.1 |
ACSM2B
|
acyl-CoA synthetase medium-chain family member 2B |
| chr7_+_73624276 | 4.39 |
ENST00000475494.1
ENST00000398475.1 |
LAT2
|
linker for activation of T cells family, member 2 |
| chr9_+_130186653 | 4.37 |
ENST00000342483.5
ENST00000543471.1 |
ZNF79
|
zinc finger protein 79 |
| chr4_+_8594477 | 4.34 |
ENST00000315782.6
|
CPZ
|
carboxypeptidase Z |
| chr16_+_20462783 | 4.33 |
ENST00000574251.1
ENST00000576361.1 ENST00000417235.2 ENST00000573854.1 ENST00000424070.1 ENST00000536134.1 ENST00000219054.6 ENST00000575690.1 ENST00000571894.1 |
ACSM2A
|
acyl-CoA synthetase medium-chain family member 2A |
| chrX_-_107975917 | 4.32 |
ENST00000563887.1
|
RP6-24A23.6
|
Uncharacterized protein |
| chr8_+_39770803 | 4.26 |
ENST00000518237.1
|
IDO1
|
indoleamine 2,3-dioxygenase 1 |
| chr8_+_133931648 | 4.21 |
ENST00000519178.1
ENST00000542445.1 |
TG
|
thyroglobulin |
| chr1_-_21044489 | 4.20 |
ENST00000247986.2
|
KIF17
|
kinesin family member 17 |
| chr11_+_111782934 | 4.19 |
ENST00000304298.3
|
HSPB2
|
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA. |
| chr14_+_22964877 | 4.17 |
ENST00000390494.1
|
TRAJ43
|
T cell receptor alpha joining 43 |
| chr1_+_66258846 | 4.13 |
ENST00000341517.4
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr12_-_52761262 | 4.12 |
ENST00000257901.3
|
KRT85
|
keratin 85 |
| chr11_-_118436707 | 4.09 |
ENST00000264020.2
ENST00000264021.3 |
IFT46
|
intraflagellar transport 46 homolog (Chlamydomonas) |
| chr3_+_119316721 | 4.09 |
ENST00000488919.1
ENST00000495992.1 |
PLA1A
|
phospholipase A1 member A |
| chrX_+_152224766 | 3.90 |
ENST00000370265.4
ENST00000447306.1 |
PNMA3
|
paraneoplastic Ma antigen 3 |
| chr19_+_55174400 | 3.89 |
ENST00000430952.2
ENST00000391734.3 ENST00000391733.3 ENST00000434286.1 |
LILRB4
|
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| chr14_+_22446680 | 3.87 |
ENST00000390443.3
|
TRAV8-6
|
T cell receptor alpha variable 8-6 |
| chr10_+_91092241 | 3.85 |
ENST00000371811.4
|
IFIT3
|
interferon-induced protein with tetratricopeptide repeats 3 |
| chr17_+_13972807 | 3.81 |
ENST00000429152.2
ENST00000261643.3 ENST00000536205.1 ENST00000537334.1 |
COX10
|
cytochrome c oxidase assembly homolog 10 (yeast) |
| chr17_-_44657017 | 3.71 |
ENST00000573185.1
ENST00000570550.1 ENST00000445552.2 ENST00000336125.5 ENST00000329240.4 ENST00000337845.7 |
ARL17A
|
ADP-ribosylation factor-like 17A |
| chr6_+_31637944 | 3.66 |
ENST00000375864.4
|
LY6G5B
|
lymphocyte antigen 6 complex, locus G5B |
| chr11_-_506316 | 3.65 |
ENST00000532055.1
ENST00000531540.1 |
RNH1
|
ribonuclease/angiogenin inhibitor 1 |
| chr3_-_109056419 | 3.60 |
ENST00000335658.6
|
DPPA4
|
developmental pluripotency associated 4 |
| chr19_+_21106081 | 3.54 |
ENST00000300540.3
ENST00000595854.1 ENST00000601284.1 ENST00000328178.8 ENST00000599885.1 ENST00000596476.1 ENST00000345030.6 |
ZNF85
|
zinc finger protein 85 |
| chr1_-_79472365 | 3.54 |
ENST00000370742.3
|
ELTD1
|
EGF, latrophilin and seven transmembrane domain containing 1 |
| chr2_-_3521518 | 3.48 |
ENST00000382093.5
|
ADI1
|
acireductone dioxygenase 1 |
| chr19_-_22193731 | 3.47 |
ENST00000601773.1
ENST00000397126.4 ENST00000601993.1 ENST00000599916.1 |
ZNF208
|
zinc finger protein 208 |
| chr4_+_128802016 | 3.47 |
ENST00000270861.5
ENST00000515069.1 ENST00000513090.1 ENST00000507249.1 |
PLK4
|
polo-like kinase 4 |
| chr10_-_70287231 | 3.43 |
ENST00000609923.1
|
SLC25A16
|
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16 |
| chr1_-_15850676 | 3.42 |
ENST00000440484.1
ENST00000333868.5 |
CASP9
|
caspase 9, apoptosis-related cysteine peptidase |
| chr5_-_55412774 | 3.39 |
ENST00000434982.2
|
ANKRD55
|
ankyrin repeat domain 55 |
| chr10_+_11784360 | 3.37 |
ENST00000379215.4
ENST00000420401.1 |
ECHDC3
|
enoyl CoA hydratase domain containing 3 |
| chr2_-_107084826 | 3.35 |
ENST00000304514.7
ENST00000409886.3 |
RGPD3
|
RANBP2-like and GRIP domain containing 3 |
| chr19_-_46142637 | 3.34 |
ENST00000590043.1
ENST00000589876.1 |
EML2
|
echinoderm microtubule associated protein like 2 |
| chr19_-_3700388 | 3.33 |
ENST00000589578.1
ENST00000537021.1 ENST00000539785.1 ENST00000335312.3 |
PIP5K1C
|
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| chr7_-_99332719 | 3.30 |
ENST00000336374.2
|
CYP3A7
|
cytochrome P450, family 3, subfamily A, polypeptide 7 |
| chr3_+_119316689 | 3.30 |
ENST00000273371.4
|
PLA1A
|
phospholipase A1 member A |
| chr17_+_48046538 | 3.27 |
ENST00000240306.3
|
DLX4
|
distal-less homeobox 4 |
| chr7_-_56160666 | 3.27 |
ENST00000297373.2
|
PHKG1
|
phosphorylase kinase, gamma 1 (muscle) |
| chr1_+_1215816 | 3.11 |
ENST00000379116.5
|
SCNN1D
|
sodium channel, non-voltage-gated 1, delta subunit |
| chr20_-_44485835 | 3.10 |
ENST00000457981.1
ENST00000426915.1 ENST00000217455.4 |
ACOT8
|
acyl-CoA thioesterase 8 |
| chr1_-_216978709 | 3.09 |
ENST00000360012.3
|
ESRRG
|
estrogen-related receptor gamma |
| chr12_-_10151773 | 3.08 |
ENST00000298527.6
ENST00000348658.4 |
CLEC1B
|
C-type lectin domain family 1, member B |
| chr7_+_99425633 | 3.02 |
ENST00000354829.2
ENST00000421837.2 ENST00000417625.1 ENST00000342499.4 ENST00000444905.1 ENST00000415413.1 ENST00000312017.5 ENST00000222382.5 |
CYP3A43
|
cytochrome P450, family 3, subfamily A, polypeptide 43 |
| chr2_-_208994548 | 3.01 |
ENST00000282141.3
|
CRYGC
|
crystallin, gamma C |
| chrX_+_56100757 | 2.89 |
ENST00000433279.1
|
AL353698.1
|
Uncharacterized protein |
| chr19_-_33360647 | 2.85 |
ENST00000590341.1
ENST00000587772.1 ENST00000023064.4 |
SLC7A9
|
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| chr6_+_24495067 | 2.84 |
ENST00000357578.3
ENST00000546278.1 ENST00000491546.1 |
ALDH5A1
|
aldehyde dehydrogenase 5 family, member A1 |
| chr5_-_135290705 | 2.80 |
ENST00000274507.1
|
LECT2
|
leukocyte cell-derived chemotaxin 2 |
| chr1_+_1215968 | 2.76 |
ENST00000338555.2
|
SCNN1D
|
sodium channel, non-voltage-gated 1, delta subunit |
| chr1_+_248020481 | 2.76 |
ENST00000366481.3
|
TRIM58
|
tripartite motif containing 58 |
| chr22_-_37976082 | 2.73 |
ENST00000215886.4
|
LGALS2
|
lectin, galactoside-binding, soluble, 2 |
| chr7_-_99381884 | 2.70 |
ENST00000336411.2
|
CYP3A4
|
cytochrome P450, family 3, subfamily A, polypeptide 4 |
| chr1_+_12834984 | 2.64 |
ENST00000357726.4
|
PRAMEF12
|
PRAME family member 12 |
| chr11_-_116708302 | 2.64 |
ENST00000375320.1
ENST00000359492.2 ENST00000375329.2 ENST00000375323.1 |
APOA1
|
apolipoprotein A-I |
| chr19_+_35862192 | 2.58 |
ENST00000597214.1
|
GPR42
|
G protein-coupled receptor 42 (gene/pseudogene) |
| chr4_-_69536346 | 2.57 |
ENST00000338206.5
|
UGT2B15
|
UDP glucuronosyltransferase 2 family, polypeptide B15 |
| chr1_+_225600404 | 2.55 |
ENST00000366845.2
|
AC092811.1
|
AC092811.1 |
| chr2_+_11679963 | 2.52 |
ENST00000263834.5
|
GREB1
|
growth regulation by estrogen in breast cancer 1 |
| chr1_+_17944832 | 2.51 |
ENST00000167825.4
|
ARHGEF10L
|
Rho guanine nucleotide exchange factor (GEF) 10-like |
| chr4_-_168155300 | 2.45 |
ENST00000541637.1
|
SPOCK3
|
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| chr18_-_44336998 | 2.36 |
ENST00000315087.7
|
ST8SIA5
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| chr1_+_120049826 | 2.36 |
ENST00000369413.3
ENST00000235547.6 ENST00000528909.1 |
HSD3B1
|
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| chr19_+_35849723 | 2.35 |
ENST00000594310.1
|
FFAR3
|
free fatty acid receptor 3 |
| chr5_+_53751445 | 2.34 |
ENST00000302005.1
|
HSPB3
|
heat shock 27kDa protein 3 |
| chr10_-_27389320 | 2.32 |
ENST00000436985.2
|
ANKRD26
|
ankyrin repeat domain 26 |
| chr17_+_28884130 | 2.27 |
ENST00000580161.1
|
TBC1D29
|
TBC1 domain family, member 29 |
| chr1_-_110613276 | 2.27 |
ENST00000369792.4
|
ALX3
|
ALX homeobox 3 |
| chr1_-_161519682 | 2.24 |
ENST00000367969.3
ENST00000443193.1 |
FCGR3A
|
Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| chr19_+_51273721 | 2.21 |
ENST00000270590.4
|
GPR32
|
G protein-coupled receptor 32 |
| chr20_-_32262165 | 2.20 |
ENST00000606690.1
ENST00000246190.6 ENST00000439478.1 ENST00000375238.4 |
NECAB3
|
N-terminal EF-hand calcium binding protein 3 |
| chr6_-_33771757 | 2.19 |
ENST00000507738.1
ENST00000266003.5 ENST00000430124.2 |
MLN
|
motilin |
| chr6_+_31554779 | 2.15 |
ENST00000376090.2
|
LST1
|
leukocyte specific transcript 1 |
| chr1_-_46642154 | 2.08 |
ENST00000540385.1
|
PIK3R3
|
phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| chr2_-_136594740 | 2.03 |
ENST00000264162.2
|
LCT
|
lactase |
| chr5_-_74162605 | 1.99 |
ENST00000389156.4
ENST00000510496.1 ENST00000380515.3 |
FAM169A
|
family with sequence similarity 169, member A |
| chr18_-_44336754 | 1.99 |
ENST00000538168.1
ENST00000536490.1 |
ST8SIA5
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| chr7_-_99381798 | 1.94 |
ENST00000415003.1
ENST00000354593.2 |
CYP3A4
|
cytochrome P450, family 3, subfamily A, polypeptide 4 |
| chr16_-_1275257 | 1.87 |
ENST00000234798.4
|
TPSG1
|
tryptase gamma 1 |
| chr17_+_26800648 | 1.85 |
ENST00000545060.1
|
SLC13A2
|
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| chr12_+_93963590 | 1.83 |
ENST00000340600.2
|
SOCS2
|
suppressor of cytokine signaling 2 |
| chr19_-_54618650 | 1.82 |
ENST00000391757.1
|
TFPT
|
TCF3 (E2A) fusion partner (in childhood Leukemia) |
| chrX_-_134429952 | 1.82 |
ENST00000370764.1
|
ZNF75D
|
zinc finger protein 75D |
| chr17_+_35767301 | 1.81 |
ENST00000225396.6
ENST00000417170.1 ENST00000590005.1 ENST00000590957.1 |
TADA2A
|
transcriptional adaptor 2A |
| chr7_+_158649242 | 1.80 |
ENST00000407559.3
|
WDR60
|
WD repeat domain 60 |
| chr12_+_57810198 | 1.69 |
ENST00000598001.1
|
AC126614.1
|
HCG1818482; Uncharacterized protein |
| chr19_+_44507091 | 1.69 |
ENST00000429154.2
ENST00000585632.1 |
ZNF230
|
zinc finger protein 230 |
| chr15_+_40531243 | 1.62 |
ENST00000558055.1
ENST00000455577.2 |
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr17_+_26800756 | 1.61 |
ENST00000537681.1
|
SLC13A2
|
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| chr1_+_160313062 | 1.60 |
ENST00000294785.5
ENST00000368063.1 ENST00000437169.1 |
NCSTN
|
nicastrin |
| chr16_+_56995854 | 1.34 |
ENST00000566128.1
|
CETP
|
cholesteryl ester transfer protein, plasma |
| chr6_+_160327974 | 1.33 |
ENST00000252660.4
|
MAS1
|
MAS1 oncogene |
| chr17_+_58677539 | 1.30 |
ENST00000305921.3
|
PPM1D
|
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| chr19_+_35861831 | 1.29 |
ENST00000454971.1
|
GPR42
|
G protein-coupled receptor 42 (gene/pseudogene) |
| chr9_-_111619239 | 1.28 |
ENST00000374667.3
|
ACTL7B
|
actin-like 7B |
| chr6_-_133055896 | 1.21 |
ENST00000367927.5
ENST00000425515.2 ENST00000207771.3 ENST00000392393.3 ENST00000450865.2 ENST00000392394.2 |
VNN3
|
vanin 3 |
| chr17_-_40828969 | 1.17 |
ENST00000591022.1
ENST00000587627.1 ENST00000293349.6 |
PLEKHH3
|
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 |
| chr1_+_52682052 | 1.17 |
ENST00000371591.1
|
ZFYVE9
|
zinc finger, FYVE domain containing 9 |
| chr12_-_81763184 | 1.15 |
ENST00000548670.1
ENST00000541570.2 ENST00000553058.1 |
PPFIA2
|
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 |
| chr12_-_323689 | 1.14 |
ENST00000428720.1
|
SLC6A12
|
solute carrier family 6 (neurotransmitter transporter), member 12 |
| chr6_+_76311736 | 1.13 |
ENST00000447266.2
|
SENP6
|
SUMO1/sentrin specific peptidase 6 |
| chr1_+_86934526 | 1.07 |
ENST00000394711.1
|
CLCA1
|
chloride channel accessory 1 |
| chr6_+_31554962 | 1.06 |
ENST00000376092.3
ENST00000376086.3 ENST00000303757.8 ENST00000376093.2 ENST00000376102.3 |
LST1
|
leukocyte specific transcript 1 |
| chr1_+_196946664 | 1.06 |
ENST00000367414.5
|
CFHR5
|
complement factor H-related 5 |
| chr1_+_174669653 | 1.04 |
ENST00000325589.5
|
RABGAP1L
|
RAB GTPase activating protein 1-like |
| chr6_-_35480705 | 1.02 |
ENST00000229771.6
|
TULP1
|
tubby like protein 1 |
| chr6_-_49430886 | 1.00 |
ENST00000274813.3
|
MUT
|
methylmalonyl CoA mutase |
| chr18_-_32924372 | 0.98 |
ENST00000261332.6
ENST00000399061.3 |
ZNF24
|
zinc finger protein 24 |
| chr17_-_40829026 | 0.94 |
ENST00000412503.1
|
PLEKHH3
|
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 |
| chr12_+_20522179 | 0.94 |
ENST00000359062.3
|
PDE3A
|
phosphodiesterase 3A, cGMP-inhibited |
| chr19_+_21324827 | 0.94 |
ENST00000600692.1
ENST00000599296.1 ENST00000594425.1 ENST00000311048.7 |
ZNF431
|
zinc finger protein 431 |
| chr19_+_35849362 | 0.90 |
ENST00000327809.4
|
FFAR3
|
free fatty acid receptor 3 |
| chr4_-_48082192 | 0.87 |
ENST00000507351.1
|
TXK
|
TXK tyrosine kinase |
| chr2_+_177025619 | 0.86 |
ENST00000410016.1
|
HOXD3
|
homeobox D3 |
| chr14_-_80697396 | 0.84 |
ENST00000557010.1
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr11_+_31531291 | 0.82 |
ENST00000350638.5
ENST00000379163.5 ENST00000395934.2 |
ELP4
|
elongator acetyltransferase complex subunit 4 |
| chr1_-_111506562 | 0.81 |
ENST00000485275.2
ENST00000369763.4 |
LRIF1
|
ligand dependent nuclear receptor interacting factor 1 |
| chr11_-_89653576 | 0.78 |
ENST00000420869.1
|
TRIM49D1
|
tripartite motif containing 49D1 |
| chr17_+_73997419 | 0.76 |
ENST00000425876.2
|
CDK3
|
cyclin-dependent kinase 3 |
| chr2_+_108443388 | 0.73 |
ENST00000354986.4
ENST00000408999.3 |
RGPD4
|
RANBP2-like and GRIP domain containing 4 |
| chr9_-_104145795 | 0.70 |
ENST00000259407.2
|
BAAT
|
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) |
| chr18_-_7117813 | 0.69 |
ENST00000389658.3
|
LAMA1
|
laminin, alpha 1 |
| chr12_+_6881678 | 0.66 |
ENST00000441671.2
ENST00000203629.2 |
LAG3
|
lymphocyte-activation gene 3 |
| chr11_-_8959758 | 0.63 |
ENST00000531618.1
|
ASCL3
|
achaete-scute family bHLH transcription factor 3 |
| chr17_-_10560619 | 0.58 |
ENST00000583535.1
|
MYH3
|
myosin, heavy chain 3, skeletal muscle, embryonic |
| chr1_-_150979333 | 0.55 |
ENST00000312210.5
|
FAM63A
|
family with sequence similarity 63, member A |
| chr5_-_35195338 | 0.53 |
ENST00000509839.1
|
PRLR
|
prolactin receptor |
| chr4_+_70146217 | 0.52 |
ENST00000335568.5
ENST00000511240.1 |
UGT2B28
|
UDP glucuronosyltransferase 2 family, polypeptide B28 |
| chr11_-_796197 | 0.49 |
ENST00000530360.1
ENST00000528606.1 ENST00000320230.5 |
SLC25A22
|
solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| chr6_+_42141029 | 0.48 |
ENST00000372958.1
|
GUCA1A
|
guanylate cyclase activator 1A (retina) |
| chr6_-_71012773 | 0.45 |
ENST00000370496.3
ENST00000357250.6 |
COL9A1
|
collagen, type IX, alpha 1 |
| chr15_+_81591757 | 0.43 |
ENST00000558332.1
|
IL16
|
interleukin 16 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RARB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 17.8 | GO:0061517 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 2.9 | 8.6 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 2.7 | 48.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 2.5 | 7.6 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 2.5 | 12.3 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 2.1 | 8.5 | GO:0048749 | compound eye development(GO:0048749) |
| 1.9 | 13.1 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 1.8 | 7.3 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 1.7 | 10.2 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 1.6 | 4.8 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 1.5 | 4.6 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
| 1.4 | 25.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 1.4 | 11.1 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 1.1 | 4.3 | GO:0036269 | swimming behavior(GO:0036269) |
| 1.0 | 15.2 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 1.0 | 6.9 | GO:0006642 | triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269) |
| 0.8 | 4.9 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.8 | 3.2 | GO:0002879 | positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879) |
| 0.7 | 28.5 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.7 | 3.5 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.7 | 3.3 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.7 | 2.6 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 0.6 | 7.9 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.5 | 3.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.5 | 4.8 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.5 | 2.9 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.5 | 4.7 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 0.5 | 4.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.4 | 4.3 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
| 0.4 | 3.5 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.4 | 6.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.4 | 7.4 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.3 | 4.1 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.3 | 1.0 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.3 | 3.9 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.3 | 3.4 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 0.3 | 6.0 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.3 | 7.5 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.3 | 3.9 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.3 | 2.0 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.3 | 12.1 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.3 | 15.6 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 3.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.3 | 3.6 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.3 | 10.1 | GO:0005980 | polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247) |
| 0.2 | 2.5 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 3.1 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.2 | 8.1 | GO:1901687 | glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687) |
| 0.2 | 1.4 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450) |
| 0.2 | 0.9 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.2 | 2.2 | GO:0042983 | amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984) |
| 0.2 | 0.7 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.2 | 0.9 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 17.4 | GO:0032945 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) |
| 0.2 | 0.9 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.2 | 2.4 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.2 | 4.4 | GO:0097503 | glycosphingolipid biosynthetic process(GO:0006688) sialylation(GO:0097503) |
| 0.2 | 3.1 | GO:0030220 | platelet formation(GO:0030220) |
| 0.2 | 4.1 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 2.2 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.1 | 8.6 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 1.3 | GO:0055091 | phospholipid homeostasis(GO:0055091) |
| 0.1 | 5.9 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 4.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 1.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.1 | 1.3 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.1 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 2.6 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 1.3 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.1 | 2.1 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.1 | 9.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.1 | 1.0 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546) |
| 0.1 | 5.9 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.1 | 0.4 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.1 | 1.6 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 0.5 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.1 | 7.0 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 1.1 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.1 | 0.7 | GO:0019530 | taurine metabolic process(GO:0019530) |
| 0.1 | 3.3 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 0.8 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.1 | 0.8 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 2.3 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.1 | 0.2 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.1 | 3.1 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 1.2 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
| 0.0 | 5.1 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 0.0 | 2.8 | GO:0001501 | skeletal system development(GO:0001501) |
| 0.0 | 0.3 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.0 | 5.2 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 4.9 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.0 | 0.5 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 2.5 | GO:0043303 | mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303) |
| 0.0 | 3.3 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.0 | 8.9 | GO:0016485 | protein processing(GO:0016485) |
| 0.0 | 0.4 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 4.1 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
| 0.0 | 1.3 | GO:0007010 | cytoskeleton organization(GO:0007010) |
| 0.0 | 3.3 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 0.6 | GO:0038096 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.0 | 5.1 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.0 | 1.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 3.4 | GO:0006839 | mitochondrial transport(GO:0006839) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 6.9 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 3.1 | 48.9 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.2 | 20.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 1.2 | 3.5 | GO:0098536 | deuterosome(GO:0098536) |
| 1.1 | 10.1 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 1.1 | 4.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 1.0 | 4.2 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.9 | 3.4 | GO:0043293 | apoptosome(GO:0043293) |
| 0.7 | 5.7 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.6 | 3.6 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.5 | 7.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.5 | 4.4 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.4 | 20.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 4.8 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.3 | 2.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.3 | 25.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.3 | 2.5 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.3 | 7.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.2 | 6.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.2 | 0.7 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 0.2 | 1.8 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.2 | 4.1 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.2 | 1.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.2 | 6.3 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.2 | 3.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 5.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 11.1 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 6.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 3.8 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.1 | 7.4 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 20.3 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.1 | 10.3 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 4.4 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 5.1 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 4.1 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 1.8 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.1 | 2.1 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 0.4 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.1 | 2.5 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 1.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 6.0 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 5.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.0 | 2.9 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 6.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.6 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 0.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 4.4 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 1.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 49.3 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 5.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.5 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 34.6 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.8 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 6.6 | GO:0005635 | nuclear envelope(GO:0005635) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 20.2 | GO:0052739 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) |
| 2.3 | 25.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.7 | 6.9 | GO:0035473 | lipase binding(GO:0035473) |
| 1.7 | 51.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.5 | 4.6 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 1.4 | 4.3 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 1.2 | 8.5 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 1.2 | 3.5 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 1.1 | 10.1 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.0 | 8.7 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.9 | 11.1 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.9 | 14.4 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.9 | 17.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.8 | 3.3 | GO:0052812 | phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) |
| 0.8 | 16.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.8 | 2.4 | GO:0004769 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769) |
| 0.8 | 4.7 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 0.7 | 2.7 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.7 | 2.6 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.6 | 4.4 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.5 | 2.0 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.5 | 9.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.5 | 2.9 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.5 | 7.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.4 | 1.3 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.4 | 3.1 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.4 | 2.2 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.4 | 10.2 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.4 | 5.9 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.4 | 6.3 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.4 | 6.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.4 | 3.8 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.4 | 3.6 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.3 | 3.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.3 | 10.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.3 | 0.9 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.3 | 1.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.3 | 7.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.3 | 7.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.3 | 4.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.3 | 1.3 | GO:0004945 | angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945) |
| 0.2 | 6.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 1.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.2 | 1.1 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 0.2 | 2.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.2 | 8.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 3.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.8 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.1 | 0.7 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 2.2 | GO:0019864 | IgG binding(GO:0019864) |
| 0.1 | 4.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 3.4 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 0.5 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 0.1 | 2.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 0.6 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.1 | 0.5 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.1 | 1.0 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 0.8 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 3.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 0.4 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 1.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.1 | 4.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 1.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 5.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.5 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.0 | 0.4 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 3.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 3.4 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.0 | 12.5 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 33.3 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 1.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 2.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 1.3 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 1.4 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.0 | 1.8 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 1.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.8 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
| 0.0 | 3.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.8 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.9 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 7.1 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.0 | 19.8 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 4.3 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 4.6 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 15.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 3.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 6.9 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 4.3 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 2.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 2.1 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 3.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 1.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 2.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 5.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 2.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 6.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.9 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 1.2 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.3 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 0.4 | NABA COLLAGENS | Genes encoding collagen proteins |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 11.1 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.8 | 13.1 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.6 | 4.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.5 | 25.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.4 | 7.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.4 | 6.6 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.4 | 6.9 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.4 | 10.1 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.3 | 4.3 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.3 | 11.2 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 16.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 3.4 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.2 | 3.4 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.2 | 3.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 8.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 9.0 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.2 | 2.0 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.2 | 4.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 2.4 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.1 | 5.8 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 3.5 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 7.0 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 17.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 5.4 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 5.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 13.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.6 | REACTOME SIGNALING BY NOTCH3 | Genes involved in Signaling by NOTCH3 |
| 0.1 | 4.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 33.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 1.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 3.0 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 4.4 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 1.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 4.0 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.1 | 4.9 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.1 | 2.4 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 5.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 0.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 1.2 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 5.0 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 0.9 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.6 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |