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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for REL
Z-value: 0.65
Motif logo
Transcription factors associated with REL
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
REL
|
ENSG00000162924.9 | REL proto-oncogene, NF-kB subunit |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| REL | hg19_v2_chr2_+_61108771_61108791 | 0.09 | 2.1e-01 | Click! |
Activity profile of REL motif
Sorted Z-values of REL motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_153599578 | 33.29 |
ENST00000360319.4
ENST00000344736.4 |
FLNA
|
filamin A, alpha |
| chr6_+_138188551 | 32.72 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr17_-_4852332 | 32.58 |
ENST00000572383.1
|
PFN1
|
profilin 1 |
| chr1_-_159894319 | 31.22 |
ENST00000320307.4
|
TAGLN2
|
transgelin 2 |
| chr5_-_150466692 | 28.39 |
ENST00000315050.7
ENST00000523338.1 ENST00000522100.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr12_+_51632638 | 24.81 |
ENST00000549732.2
|
DAZAP2
|
DAZ associated protein 2 |
| chr18_+_3252265 | 24.20 |
ENST00000580887.1
ENST00000536605.1 |
MYL12A
|
myosin, light chain 12A, regulatory, non-sarcomeric |
| chr10_-_97050777 | 24.10 |
ENST00000329399.6
|
PDLIM1
|
PDZ and LIM domain 1 |
| chr16_-_88717482 | 22.19 |
ENST00000261623.3
|
CYBA
|
cytochrome b-245, alpha polypeptide |
| chr16_-_88717423 | 20.03 |
ENST00000568278.1
ENST00000569359.1 ENST00000567174.1 |
CYBA
|
cytochrome b-245, alpha polypeptide |
| chr1_-_113249948 | 19.27 |
ENST00000339083.7
ENST00000369642.3 |
RHOC
|
ras homolog family member C |
| chr2_+_102314161 | 19.07 |
ENST00000425019.1
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4 |
| chr19_+_41725088 | 19.03 |
ENST00000301178.4
|
AXL
|
AXL receptor tyrosine kinase |
| chr5_-_150460914 | 18.17 |
ENST00000389378.2
|
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr1_+_165796753 | 17.69 |
ENST00000367879.4
|
UCK2
|
uridine-cytidine kinase 2 |
| chr11_-_58345569 | 17.54 |
ENST00000528954.1
ENST00000528489.1 |
LPXN
|
leupaxin |
| chr12_+_51632600 | 17.06 |
ENST00000549555.1
ENST00000439799.2 ENST00000425012.2 |
DAZAP2
|
DAZ associated protein 2 |
| chr19_-_50143452 | 17.02 |
ENST00000246792.3
|
RRAS
|
related RAS viral (r-ras) oncogene homolog |
| chr12_+_56211703 | 16.94 |
ENST00000243045.5
ENST00000552672.1 ENST00000550836.1 |
ORMDL2
|
ORM1-like 2 (S. cerevisiae) |
| chr20_-_33872548 | 16.56 |
ENST00000374443.3
|
EIF6
|
eukaryotic translation initiation factor 6 |
| chr20_-_33872518 | 16.48 |
ENST00000374436.3
|
EIF6
|
eukaryotic translation initiation factor 6 |
| chr5_+_82767284 | 16.44 |
ENST00000265077.3
|
VCAN
|
versican |
| chr14_-_69446034 | 16.13 |
ENST00000193403.6
|
ACTN1
|
actinin, alpha 1 |
| chr14_-_24616426 | 15.43 |
ENST00000216802.5
|
PSME2
|
proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| chr2_+_114647504 | 14.81 |
ENST00000263238.2
|
ACTR3
|
ARP3 actin-related protein 3 homolog (yeast) |
| chr17_-_7590745 | 14.71 |
ENST00000514944.1
ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4 |
TP53
|
tumor protein p53 |
| chr4_+_74735102 | 14.58 |
ENST00000395761.3
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| chr6_+_29910301 | 13.79 |
ENST00000376809.5
ENST00000376802.2 |
HLA-A
|
major histocompatibility complex, class I, A |
| chr4_-_103749179 | 13.62 |
ENST00000502690.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr2_+_238600933 | 13.52 |
ENST00000420665.1
ENST00000392000.4 |
LRRFIP1
|
leucine rich repeat (in FLII) interacting protein 1 |
| chr3_-_49142178 | 13.14 |
ENST00000452739.1
ENST00000414533.1 ENST00000417025.1 |
QARS
|
glutaminyl-tRNA synthetase |
| chr6_+_32821924 | 12.78 |
ENST00000374859.2
ENST00000453265.2 |
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9 |
| chr22_-_43036607 | 12.43 |
ENST00000505920.1
|
ATP5L2
|
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2 |
| chr18_+_21529811 | 12.33 |
ENST00000588004.1
|
LAMA3
|
laminin, alpha 3 |
| chr9_-_117880477 | 12.27 |
ENST00000534839.1
ENST00000340094.3 ENST00000535648.1 ENST00000346706.3 ENST00000345230.3 ENST00000350763.4 |
TNC
|
tenascin C |
| chr21_+_34775772 | 12.24 |
ENST00000405436.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr11_+_102188224 | 12.12 |
ENST00000263464.3
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr8_-_49834299 | 12.12 |
ENST00000396822.1
|
SNAI2
|
snail family zinc finger 2 |
| chr4_-_103749205 | 12.06 |
ENST00000508249.1
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr10_+_17270214 | 12.00 |
ENST00000544301.1
|
VIM
|
vimentin |
| chr12_-_49318715 | 11.91 |
ENST00000444214.2
|
FKBP11
|
FK506 binding protein 11, 19 kDa |
| chr6_-_31550192 | 11.48 |
ENST00000429299.2
ENST00000446745.2 |
LTB
|
lymphotoxin beta (TNF superfamily, member 3) |
| chr17_-_61920280 | 11.30 |
ENST00000448276.2
ENST00000577990.1 |
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 |
| chr2_+_90153696 | 11.01 |
ENST00000417279.2
|
IGKV3D-15
|
immunoglobulin kappa variable 3D-15 (gene/pseudogene) |
| chr14_-_35873856 | 10.95 |
ENST00000553342.1
ENST00000216797.5 ENST00000557140.1 |
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| chr21_+_34775698 | 10.79 |
ENST00000381995.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr17_-_3704500 | 10.22 |
ENST00000263087.4
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| chr12_+_51632508 | 10.14 |
ENST00000449723.3
|
DAZAP2
|
DAZ associated protein 2 |
| chr14_-_35099315 | 10.11 |
ENST00000396526.3
ENST00000396534.3 ENST00000355110.5 ENST00000557265.1 |
SNX6
|
sorting nexin 6 |
| chr3_-_49142504 | 10.03 |
ENST00000306125.6
ENST00000420147.2 |
QARS
|
glutaminyl-tRNA synthetase |
| chr1_-_32403903 | 10.02 |
ENST00000344035.6
ENST00000356536.3 |
PTP4A2
|
protein tyrosine phosphatase type IVA, member 2 |
| chr7_-_16844611 | 10.01 |
ENST00000401412.1
ENST00000419304.2 |
AGR2
|
anterior gradient 2 |
| chr21_+_34775181 | 9.98 |
ENST00000290219.6
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr1_-_65432171 | 9.95 |
ENST00000342505.4
|
JAK1
|
Janus kinase 1 |
| chr17_-_73178599 | 9.92 |
ENST00000578238.1
|
SUMO2
|
small ubiquitin-like modifier 2 |
| chr2_+_131975882 | 9.81 |
ENST00000356920.5
ENST00000358087.5 |
POTEE
|
POTE ankyrin domain family, member E |
| chr1_+_16767195 | 9.57 |
ENST00000504551.2
ENST00000457722.2 ENST00000406746.1 ENST00000443980.2 |
NECAP2
|
NECAP endocytosis associated 2 |
| chr6_-_31774714 | 9.53 |
ENST00000375661.5
|
LSM2
|
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| chr11_+_102188272 | 9.42 |
ENST00000532808.1
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr12_-_122985494 | 9.33 |
ENST00000336229.4
|
ZCCHC8
|
zinc finger, CCHC domain containing 8 |
| chr3_+_52719936 | 9.29 |
ENST00000418458.1
ENST00000394799.2 |
GNL3
|
guanine nucleotide binding protein-like 3 (nucleolar) |
| chr14_+_103589789 | 9.25 |
ENST00000558056.1
ENST00000560869.1 |
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2 |
| chr19_+_41725140 | 9.03 |
ENST00000359092.3
|
AXL
|
AXL receptor tyrosine kinase |
| chr8_-_49833978 | 8.94 |
ENST00000020945.1
|
SNAI2
|
snail family zinc finger 2 |
| chr4_-_185395672 | 8.69 |
ENST00000393593.3
|
IRF2
|
interferon regulatory factor 2 |
| chr12_-_122985067 | 8.59 |
ENST00000540586.1
ENST00000543897.1 |
ZCCHC8
|
zinc finger, CCHC domain containing 8 |
| chr1_-_27216729 | 8.55 |
ENST00000431781.2
ENST00000374135.4 |
GPN2
|
GPN-loop GTPase 2 |
| chr3_-_183967296 | 8.51 |
ENST00000455059.1
ENST00000445626.2 |
ALG3
|
ALG3, alpha-1,3- mannosyltransferase |
| chr11_+_66406088 | 8.34 |
ENST00000310092.7
ENST00000396053.4 ENST00000408993.2 |
RBM4
|
RNA binding motif protein 4 |
| chr12_-_9913489 | 8.24 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr2_-_113594279 | 8.13 |
ENST00000416750.1
ENST00000418817.1 ENST00000263341.2 |
IL1B
|
interleukin 1, beta |
| chr10_+_89419370 | 8.10 |
ENST00000361175.4
ENST00000456849.1 |
PAPSS2
|
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| chr4_+_169418195 | 8.07 |
ENST00000261509.6
ENST00000335742.7 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr1_-_35658736 | 8.04 |
ENST00000357214.5
|
SFPQ
|
splicing factor proline/glutamine-rich |
| chr15_+_22892663 | 7.91 |
ENST00000313077.7
ENST00000561274.1 ENST00000560848.1 |
CYFIP1
|
cytoplasmic FMR1 interacting protein 1 |
| chr10_-_96122682 | 7.80 |
ENST00000371361.3
|
NOC3L
|
nucleolar complex associated 3 homolog (S. cerevisiae) |
| chr2_-_89247338 | 7.75 |
ENST00000496168.1
|
IGKV1-5
|
immunoglobulin kappa variable 1-5 |
| chr1_-_209824643 | 7.62 |
ENST00000391911.1
ENST00000415782.1 |
LAMB3
|
laminin, beta 3 |
| chr12_+_102271129 | 7.56 |
ENST00000258534.8
|
DRAM1
|
DNA-damage regulated autophagy modulator 1 |
| chr2_+_90077680 | 7.51 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr20_-_43977055 | 7.50 |
ENST00000372733.3
ENST00000537976.1 |
SDC4
|
syndecan 4 |
| chr1_-_27816641 | 6.92 |
ENST00000430629.2
|
WASF2
|
WAS protein family, member 2 |
| chr22_+_22676808 | 6.90 |
ENST00000390290.2
|
IGLV1-51
|
immunoglobulin lambda variable 1-51 |
| chr10_+_90750378 | 6.76 |
ENST00000355740.2
ENST00000352159.4 |
FAS
|
Fas cell surface death receptor |
| chr11_+_19798964 | 6.73 |
ENST00000527559.2
|
NAV2
|
neuron navigator 2 |
| chr1_-_231560790 | 6.67 |
ENST00000366641.3
|
EGLN1
|
egl-9 family hypoxia-inducible factor 1 |
| chr12_+_51633061 | 6.61 |
ENST00000551313.1
|
DAZAP2
|
DAZ associated protein 2 |
| chr2_+_208394616 | 6.61 |
ENST00000432329.2
ENST00000353267.3 ENST00000445803.1 |
CREB1
|
cAMP responsive element binding protein 1 |
| chr14_-_54955721 | 6.56 |
ENST00000554908.1
|
GMFB
|
glia maturation factor, beta |
| chr1_+_179050512 | 6.51 |
ENST00000367627.3
|
TOR3A
|
torsin family 3, member A |
| chr11_-_65381643 | 6.50 |
ENST00000309100.3
ENST00000529839.1 ENST00000526293.1 |
MAP3K11
|
mitogen-activated protein kinase kinase kinase 11 |
| chr6_-_127664736 | 6.43 |
ENST00000368291.2
ENST00000309620.9 ENST00000454859.3 |
ECHDC1
|
enoyl CoA hydratase domain containing 1 |
| chr12_+_53491220 | 6.36 |
ENST00000548547.1
ENST00000301464.3 |
IGFBP6
|
insulin-like growth factor binding protein 6 |
| chr17_+_49337881 | 6.24 |
ENST00000225298.7
|
UTP18
|
UTP18 small subunit (SSU) processome component homolog (yeast) |
| chr19_-_50370509 | 6.24 |
ENST00000596014.1
|
PNKP
|
polynucleotide kinase 3'-phosphatase |
| chr19_-_6591113 | 6.21 |
ENST00000423145.3
ENST00000245903.3 |
CD70
|
CD70 molecule |
| chr2_+_228678550 | 6.12 |
ENST00000409189.3
ENST00000358813.4 |
CCL20
|
chemokine (C-C motif) ligand 20 |
| chr21_+_34638656 | 6.10 |
ENST00000290200.2
|
IL10RB
|
interleukin 10 receptor, beta |
| chr4_-_54930790 | 6.07 |
ENST00000263921.3
|
CHIC2
|
cysteine-rich hydrophobic domain 2 |
| chr9_-_132805430 | 6.07 |
ENST00000446176.2
ENST00000355681.3 ENST00000420781.1 |
FNBP1
|
formin binding protein 1 |
| chr6_-_127664683 | 6.07 |
ENST00000528402.1
ENST00000454591.2 |
ECHDC1
|
enoyl CoA hydratase domain containing 1 |
| chr6_-_32821599 | 6.06 |
ENST00000354258.4
|
TAP1
|
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| chr16_+_2820912 | 5.86 |
ENST00000570539.1
|
SRRM2
|
serine/arginine repetitive matrix 2 |
| chr16_+_31044812 | 5.75 |
ENST00000313843.3
|
STX4
|
syntaxin 4 |
| chr4_-_103749313 | 5.66 |
ENST00000394803.5
|
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chrX_-_48755030 | 5.63 |
ENST00000490755.2
ENST00000465150.2 ENST00000495490.2 |
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| chr2_-_89310012 | 5.53 |
ENST00000493819.1
|
IGKV1-9
|
immunoglobulin kappa variable 1-9 |
| chr11_+_19799327 | 5.52 |
ENST00000540292.1
|
NAV2
|
neuron navigator 2 |
| chr17_+_34640031 | 5.45 |
ENST00000339270.6
ENST00000482104.1 |
CCL4L2
|
chemokine (C-C motif) ligand 4-like 2 |
| chr15_+_52311398 | 5.45 |
ENST00000261845.5
|
MAPK6
|
mitogen-activated protein kinase 6 |
| chr3_+_179322573 | 5.42 |
ENST00000493866.1
ENST00000472629.1 ENST00000482604.1 |
NDUFB5
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
| chr8_+_70404996 | 5.33 |
ENST00000402687.4
ENST00000419716.3 |
SULF1
|
sulfatase 1 |
| chr12_+_7055631 | 5.23 |
ENST00000543115.1
ENST00000399448.1 |
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr4_-_103749105 | 5.03 |
ENST00000394801.4
ENST00000394804.2 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr16_+_27325202 | 4.95 |
ENST00000395762.2
ENST00000562142.1 ENST00000561742.1 ENST00000543915.2 ENST00000449195.1 ENST00000380922.3 ENST00000563002.1 |
IL4R
|
interleukin 4 receptor |
| chr2_+_208394455 | 4.91 |
ENST00000430624.1
|
CREB1
|
cAMP responsive element binding protein 1 |
| chr15_+_85923797 | 4.88 |
ENST00000559362.1
|
AKAP13
|
A kinase (PRKA) anchor protein 13 |
| chr8_-_105601134 | 4.87 |
ENST00000276654.5
ENST00000424843.2 |
LRP12
|
low density lipoprotein receptor-related protein 12 |
| chrX_+_48755183 | 4.76 |
ENST00000376563.1
ENST00000376566.4 |
PQBP1
|
polyglutamine binding protein 1 |
| chr4_-_74864386 | 4.62 |
ENST00000296027.4
|
CXCL5
|
chemokine (C-X-C motif) ligand 5 |
| chrX_+_117861535 | 4.59 |
ENST00000371666.3
ENST00000371642.1 |
IL13RA1
|
interleukin 13 receptor, alpha 1 |
| chr12_-_76425368 | 4.53 |
ENST00000602540.1
|
PHLDA1
|
pleckstrin homology-like domain, family A, member 1 |
| chr4_-_103748880 | 4.53 |
ENST00000453744.2
ENST00000349311.8 |
UBE2D3
|
ubiquitin-conjugating enzyme E2D 3 |
| chr7_-_47579188 | 4.49 |
ENST00000398879.1
ENST00000355730.3 ENST00000442536.2 ENST00000458317.2 |
TNS3
|
tensin 3 |
| chr14_-_106610852 | 4.48 |
ENST00000390603.2
|
IGHV3-15
|
immunoglobulin heavy variable 3-15 |
| chr1_-_32110467 | 4.41 |
ENST00000440872.2
ENST00000373703.4 |
PEF1
|
penta-EF-hand domain containing 1 |
| chr16_+_53088885 | 4.39 |
ENST00000566029.1
ENST00000447540.1 |
CHD9
|
chromodomain helicase DNA binding protein 9 |
| chr17_+_34639793 | 4.37 |
ENST00000394465.2
ENST00000394463.2 ENST00000378342.4 |
CCL4L2
|
chemokine (C-C motif) ligand 4-like 2 |
| chr2_-_29093132 | 4.32 |
ENST00000306108.5
|
TRMT61B
|
tRNA methyltransferase 61 homolog B (S. cerevisiae) |
| chr2_-_191885686 | 4.32 |
ENST00000432058.1
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa |
| chr6_-_131291572 | 4.30 |
ENST00000529208.1
|
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr5_+_14143728 | 4.29 |
ENST00000344204.4
ENST00000537187.1 |
TRIO
|
trio Rho guanine nucleotide exchange factor |
| chr12_-_57023995 | 4.21 |
ENST00000549884.1
ENST00000546695.1 |
BAZ2A
|
bromodomain adjacent to zinc finger domain, 2A |
| chr3_+_184081137 | 4.19 |
ENST00000443489.1
|
POLR2H
|
polymerase (RNA) II (DNA directed) polypeptide H |
| chr3_-_139108475 | 4.15 |
ENST00000515006.1
ENST00000513274.1 ENST00000514508.1 ENST00000507777.1 ENST00000512153.1 ENST00000333188.5 |
COPB2
|
coatomer protein complex, subunit beta 2 (beta prime) |
| chr10_+_104154229 | 4.09 |
ENST00000428099.1
ENST00000369966.3 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr10_+_90750493 | 4.02 |
ENST00000357339.2
ENST00000355279.2 |
FAS
|
Fas cell surface death receptor |
| chr8_-_23712312 | 4.02 |
ENST00000290271.2
|
STC1
|
stanniocalcin 1 |
| chr10_+_104155450 | 3.97 |
ENST00000471698.1
ENST00000189444.6 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr2_-_27357479 | 3.95 |
ENST00000406567.3
ENST00000260643.2 |
PREB
|
prolactin regulatory element binding |
| chr15_+_67430339 | 3.88 |
ENST00000439724.3
|
SMAD3
|
SMAD family member 3 |
| chr15_-_20193370 | 3.78 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr6_-_127664475 | 3.78 |
ENST00000474289.2
ENST00000534442.1 ENST00000368289.2 ENST00000525745.1 ENST00000430841.2 |
ECHDC1
|
enoyl CoA hydratase domain containing 1 |
| chr1_-_44818599 | 3.77 |
ENST00000537474.1
|
ERI3
|
ERI1 exoribonuclease family member 3 |
| chr2_-_88355241 | 3.74 |
ENST00000347055.3
|
KRCC1
|
lysine-rich coiled-coil 1 |
| chr18_+_21452804 | 3.66 |
ENST00000269217.6
|
LAMA3
|
laminin, alpha 3 |
| chr22_+_22712087 | 3.60 |
ENST00000390294.2
|
IGLV1-47
|
immunoglobulin lambda variable 1-47 |
| chr1_-_151431647 | 3.56 |
ENST00000368863.2
ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1 |
POGZ
|
pogo transposable element with ZNF domain |
| chr8_+_123793633 | 3.43 |
ENST00000314393.4
|
ZHX2
|
zinc fingers and homeoboxes 2 |
| chr12_-_77272765 | 3.41 |
ENST00000547435.1
ENST00000552330.1 ENST00000546966.1 ENST00000311083.5 |
CSRP2
|
cysteine and glycine-rich protein 2 |
| chr3_+_179322481 | 3.39 |
ENST00000259037.3
|
NDUFB5
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
| chr5_+_112312416 | 3.39 |
ENST00000389063.2
|
DCP2
|
decapping mRNA 2 |
| chr4_+_74702214 | 3.23 |
ENST00000226317.5
ENST00000515050.1 |
CXCL6
|
chemokine (C-X-C motif) ligand 6 |
| chr19_+_41256764 | 3.23 |
ENST00000243563.3
ENST00000601253.1 ENST00000597353.1 ENST00000599362.1 |
SNRPA
|
small nuclear ribonucleoprotein polypeptide A |
| chr9_+_130911723 | 2.98 |
ENST00000277480.2
ENST00000373013.2 ENST00000540948.1 |
LCN2
|
lipocalin 2 |
| chr2_+_219264466 | 2.92 |
ENST00000273062.2
|
CTDSP1
|
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| chr11_-_61734599 | 2.83 |
ENST00000532601.1
|
FTH1
|
ferritin, heavy polypeptide 1 |
| chr1_+_63833261 | 2.83 |
ENST00000371108.4
|
ALG6
|
ALG6, alpha-1,3-glucosyltransferase |
| chr12_-_57504069 | 2.82 |
ENST00000543873.2
ENST00000554663.1 ENST00000557635.1 |
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr19_-_57967854 | 2.78 |
ENST00000321039.3
|
VN1R1
|
vomeronasal 1 receptor 1 |
| chr6_+_31683117 | 2.68 |
ENST00000375825.3
ENST00000375824.1 |
LY6G6D
|
lymphocyte antigen 6 complex, locus G6D |
| chr4_+_26322185 | 2.66 |
ENST00000361572.6
|
RBPJ
|
recombination signal binding protein for immunoglobulin kappa J region |
| chr9_+_130911770 | 2.63 |
ENST00000372998.1
|
LCN2
|
lipocalin 2 |
| chr17_+_80477571 | 2.62 |
ENST00000335255.5
|
FOXK2
|
forkhead box K2 |
| chr2_+_208394794 | 2.58 |
ENST00000536726.1
ENST00000374397.4 ENST00000452474.1 |
CREB1
|
cAMP responsive element binding protein 1 |
| chr17_+_40985407 | 2.57 |
ENST00000586114.1
ENST00000590720.1 ENST00000585805.1 ENST00000541124.1 ENST00000441946.2 ENST00000591152.1 ENST00000589469.1 ENST00000293362.3 ENST00000592169.1 |
PSME3
|
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
| chr10_-_29923893 | 2.56 |
ENST00000355867.4
|
SVIL
|
supervillin |
| chr6_-_29527702 | 2.56 |
ENST00000377050.4
|
UBD
|
ubiquitin D |
| chr11_-_75062730 | 2.53 |
ENST00000420843.2
ENST00000360025.3 |
ARRB1
|
arrestin, beta 1 |
| chr1_-_29508321 | 2.53 |
ENST00000546138.1
|
SRSF4
|
serine/arginine-rich splicing factor 4 |
| chr2_+_162016916 | 2.46 |
ENST00000405852.1
|
TANK
|
TRAF family member-associated NFKB activator |
| chr2_+_220094479 | 2.42 |
ENST00000323348.5
ENST00000453432.1 ENST00000409849.1 ENST00000416565.1 ENST00000410034.3 ENST00000447157.1 |
ANKZF1
|
ankyrin repeat and zinc finger domain containing 1 |
| chr2_+_204192942 | 2.22 |
ENST00000295851.5
ENST00000261017.5 |
ABI2
|
abl-interactor 2 |
| chr1_+_235530675 | 2.18 |
ENST00000366601.3
ENST00000406207.1 ENST00000543662.1 |
TBCE
|
tubulin folding cofactor E |
| chr11_+_7597639 | 2.10 |
ENST00000533792.1
|
PPFIBP2
|
PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| chr6_-_131384373 | 2.01 |
ENST00000392427.3
ENST00000525271.1 ENST00000527411.1 |
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr3_+_197518100 | 1.96 |
ENST00000438796.2
ENST00000414675.2 ENST00000441090.2 ENST00000334859.4 ENST00000425562.2 |
LRCH3
|
leucine-rich repeats and calponin homology (CH) domain containing 3 |
| chr2_-_43453734 | 1.93 |
ENST00000282388.3
|
ZFP36L2
|
ZFP36 ring finger protein-like 2 |
| chr21_+_46875424 | 1.86 |
ENST00000359759.4
|
COL18A1
|
collagen, type XVIII, alpha 1 |
| chr6_-_131384347 | 1.81 |
ENST00000530481.1
|
EPB41L2
|
erythrocyte membrane protein band 4.1-like 2 |
| chr6_+_88299833 | 1.72 |
ENST00000392844.3
ENST00000257789.4 ENST00000546266.1 ENST00000417380.2 |
ORC3
|
origin recognition complex, subunit 3 |
| chr12_+_123465033 | 1.69 |
ENST00000454885.2
|
ARL6IP4
|
ADP-ribosylation-like factor 6 interacting protein 4 |
| chr11_+_120255997 | 1.57 |
ENST00000532993.1
|
ARHGEF12
|
Rho guanine nucleotide exchange factor (GEF) 12 |
| chr1_-_226595741 | 1.54 |
ENST00000366794.5
ENST00000366792.1 ENST00000366791.5 |
PARP1
|
poly (ADP-ribose) polymerase 1 |
| chr14_+_103243813 | 1.51 |
ENST00000560371.1
ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1 |
TRAF3
|
TNF receptor-associated factor 3 |
| chr1_-_93426998 | 1.49 |
ENST00000370310.4
|
FAM69A
|
family with sequence similarity 69, member A |
| chr4_+_169418255 | 1.49 |
ENST00000505667.1
ENST00000511948.1 |
PALLD
|
palladin, cytoskeletal associated protein |
| chr12_-_86230315 | 1.47 |
ENST00000361228.3
|
RASSF9
|
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 |
| chr9_-_115095123 | 1.38 |
ENST00000458258.1
|
PTBP3
|
polypyrimidine tract binding protein 3 |
| chr18_+_21452964 | 1.33 |
ENST00000587184.1
|
LAMA3
|
laminin, alpha 3 |
| chr2_+_173940668 | 1.31 |
ENST00000375213.3
|
MLTK
|
Mitogen-activated protein kinase kinase kinase MLT |
| chr1_+_207262170 | 1.29 |
ENST00000367078.3
|
C4BPB
|
complement component 4 binding protein, beta |
| chr19_+_14142535 | 1.27 |
ENST00000263379.2
|
IL27RA
|
interleukin 27 receptor, alpha |
| chr6_-_30080863 | 1.24 |
ENST00000540829.1
|
TRIM31
|
tripartite motif containing 31 |
| chr5_+_150591678 | 1.16 |
ENST00000523466.1
|
GM2A
|
GM2 ganglioside activator |
| chr11_+_65190245 | 1.16 |
ENST00000499732.1
ENST00000501122.2 ENST00000601801.1 |
NEAT1
|
nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| chr2_-_18741882 | 1.07 |
ENST00000381249.3
|
RDH14
|
retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| chr1_-_202130702 | 1.05 |
ENST00000309017.3
ENST00000477554.1 ENST00000492451.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr14_-_53417732 | 1.05 |
ENST00000399304.3
ENST00000395631.2 ENST00000341590.3 ENST00000343279.4 |
FERMT2
|
fermitin family member 2 |
| chr3_-_119379719 | 0.93 |
ENST00000493094.1
|
POPDC2
|
popeye domain containing 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of REL
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.5 | 46.6 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 10.9 | 32.7 | GO:0034146 | B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) |
| 8.4 | 42.2 | GO:1904845 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 8.3 | 33.0 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 8.2 | 8.2 | GO:0035690 | cellular response to drug(GO:0035690) |
| 7.7 | 23.2 | GO:0006425 | glutaminyl-tRNA aminoacylation(GO:0006425) |
| 7.0 | 21.1 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 5.6 | 16.9 | GO:0090155 | negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) |
| 5.5 | 33.3 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 4.9 | 14.8 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 4.9 | 14.7 | GO:0051097 | negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252) |
| 4.7 | 28.1 | GO:2000669 | positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669) |
| 4.5 | 4.5 | GO:0045210 | FasL biosynthetic process(GO:0045210) |
| 4.4 | 17.7 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 4.1 | 12.3 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 4.0 | 40.5 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 3.6 | 10.9 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 3.2 | 19.3 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 3.1 | 12.2 | GO:0021564 | vagus nerve development(GO:0021564) |
| 2.8 | 8.5 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 2.8 | 22.8 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 2.7 | 8.1 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
| 2.4 | 21.5 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 2.3 | 11.5 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
| 2.0 | 6.1 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 2.0 | 8.1 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 2.0 | 8.1 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 2.0 | 8.0 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 1.9 | 5.8 | GO:1902568 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 1.9 | 11.3 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 1.8 | 10.8 | GO:0097527 | Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527) |
| 1.7 | 10.0 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 1.6 | 4.8 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 1.5 | 6.1 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 1.5 | 7.5 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 1.4 | 10.1 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 1.4 | 4.3 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 1.4 | 13.8 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 1.4 | 46.8 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 1.3 | 12.0 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 1.2 | 6.2 | GO:0098502 | DNA dephosphorylation(GO:0098502) |
| 1.1 | 5.6 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 1.1 | 6.7 | GO:0051342 | regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 1.0 | 15.0 | GO:0051639 | actin filament network formation(GO:0051639) |
| 1.0 | 4.9 | GO:1990834 | response to odorant(GO:1990834) |
| 0.9 | 6.6 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.9 | 6.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.9 | 2.7 | GO:1905068 | arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.9 | 24.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.8 | 9.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.8 | 36.9 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.8 | 22.7 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.8 | 3.9 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.7 | 4.4 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.7 | 2.2 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.7 | 4.3 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.7 | 2.8 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.7 | 11.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.7 | 9.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.7 | 16.4 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.6 | 0.6 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.6 | 5.3 | GO:0060686 | negative regulation of prostatic bud formation(GO:0060686) |
| 0.6 | 8.1 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.6 | 1.7 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.6 | 11.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.5 | 4.9 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.5 | 7.8 | GO:0045444 | fat cell differentiation(GO:0045444) |
| 0.5 | 1.5 | GO:0018312 | peptidyl-serine ADP-ribosylation(GO:0018312) |
| 0.5 | 2.6 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.5 | 5.9 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.5 | 3.4 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.4 | 4.0 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.4 | 11.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.4 | 9.6 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 6.9 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855) |
| 0.4 | 2.8 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.4 | 1.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.4 | 5.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.4 | 0.7 | GO:0002232 | leukocyte chemotaxis involved in inflammatory response(GO:0002232) |
| 0.4 | 1.8 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.3 | 0.9 | GO:0002027 | regulation of heart rate(GO:0002027) |
| 0.3 | 9.5 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.3 | 30.8 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) |
| 0.3 | 3.6 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.3 | 12.4 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.3 | 24.2 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.3 | 9.9 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.3 | 1.9 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.3 | 0.5 | GO:0045080 | positive regulation of chemokine biosynthetic process(GO:0045080) |
| 0.2 | 11.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.2 | 4.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.2 | 4.6 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
| 0.2 | 35.3 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 2.3 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.2 | 0.8 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.2 | 7.6 | GO:0010506 | regulation of autophagy(GO:0010506) |
| 0.2 | 0.8 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.2 | 31.2 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.2 | 6.4 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.2 | 0.8 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.2 | 6.2 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.1 | 3.3 | GO:1900363 | regulation of mRNA polyadenylation(GO:1900363) |
| 0.1 | 1.2 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.1 | 4.5 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.1 | 4.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.1 | 8.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 0.7 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.1 | 1.3 | GO:0002829 | negative regulation of type 2 immune response(GO:0002829) |
| 0.1 | 8.2 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.1 | 8.7 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.1 | 0.6 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.1 | 2.7 | GO:1905144 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 0.6 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.1 | 11.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 5.1 | GO:0001895 | retina homeostasis(GO:0001895) |
| 0.1 | 5.4 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.1 | 4.8 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
| 0.1 | 4.2 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 0.8 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 2.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 0.3 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.1 | 0.7 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.1 | 2.6 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 1.0 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 6.5 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.1 | 23.7 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.1 | 4.2 | GO:0006306 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.1 | 10.6 | GO:0051896 | regulation of protein kinase B signaling(GO:0051896) |
| 0.0 | 0.3 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
| 0.0 | 0.7 | GO:0007620 | copulation(GO:0007620) |
| 0.0 | 6.4 | GO:0045665 | negative regulation of neuron differentiation(GO:0045665) |
| 0.0 | 0.3 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.0 | 1.1 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 0.5 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
| 0.0 | 0.3 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
| 0.0 | 0.4 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.0 | 3.4 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.0 | 4.8 | GO:0097191 | extrinsic apoptotic signaling pathway(GO:0097191) |
| 0.0 | 0.3 | GO:0051607 | defense response to virus(GO:0051607) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.1 | 33.3 | GO:0031523 | Myb complex(GO:0031523) |
| 4.2 | 16.9 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 3.1 | 24.9 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 3.0 | 18.0 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 2.5 | 42.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 2.4 | 4.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 2.2 | 24.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 2.0 | 10.1 | GO:0097422 | tubular endosome(GO:0097422) |
| 2.0 | 8.1 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 1.9 | 28.1 | GO:0033643 | host cell part(GO:0033643) |
| 1.6 | 11.3 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 1.6 | 12.8 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 1.4 | 4.3 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 1.4 | 9.5 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 1.3 | 18.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 1.3 | 13.8 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 1.2 | 6.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.1 | 9.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 1.1 | 23.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 1.1 | 16.1 | GO:0005916 | fascia adherens(GO:0005916) |
| 1.1 | 33.0 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 1.0 | 6.1 | GO:0042825 | TAP complex(GO:0042825) |
| 1.0 | 8.0 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.8 | 4.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.8 | 14.8 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.7 | 5.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.7 | 2.8 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.7 | 12.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.6 | 6.4 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.6 | 8.1 | GO:0008091 | spectrin(GO:0008091) |
| 0.6 | 1.7 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.5 | 29.6 | GO:0002102 | podosome(GO:0002102) |
| 0.5 | 19.3 | GO:0032420 | stereocilium(GO:0032420) |
| 0.5 | 2.7 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.5 | 1.5 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.5 | 3.9 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.5 | 5.2 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.5 | 5.6 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.4 | 11.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.4 | 9.3 | GO:0000145 | exocyst(GO:0000145) |
| 0.4 | 4.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.3 | 5.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.3 | 1.2 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.3 | 14.7 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.3 | 62.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 0.5 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.3 | 24.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.3 | 9.6 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.3 | 5.0 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.2 | 18.7 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.2 | 4.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.2 | 10.2 | GO:0008305 | integrin complex(GO:0008305) |
| 0.2 | 2.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.2 | 3.4 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.2 | 23.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.2 | 21.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 23.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 2.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.2 | 3.2 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.2 | 11.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 4.0 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 8.8 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 6.1 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.1 | 12.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 4.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 10.0 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 36.1 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 2.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 17.4 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.1 | 39.8 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.1 | 6.7 | GO:0005769 | early endosome(GO:0005769) |
| 0.1 | 4.8 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 13.3 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 17.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 6.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.5 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.3 | GO:0044217 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.0 | 0.8 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 20.9 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 0.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 8.0 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 0.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.5 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 0.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.7 | GO:0001650 | fibrillar center(GO:0001650) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.3 | 33.3 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 7.7 | 23.2 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 6.6 | 33.0 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 6.6 | 33.0 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 5.4 | 16.3 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 3.3 | 32.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 2.8 | 8.5 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 2.7 | 32.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 2.7 | 8.1 | GO:0004779 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 2.6 | 18.0 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 2.5 | 17.7 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 2.5 | 10.0 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 2.4 | 19.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 2.2 | 10.8 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
| 2.1 | 42.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 2.0 | 6.1 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 2.0 | 12.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 1.8 | 28.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.6 | 4.9 | GO:0004913 | interleukin-4 receptor activity(GO:0004913) |
| 1.6 | 14.7 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 1.6 | 6.5 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 1.6 | 4.9 | GO:0097158 | pre-mRNA intronic pyrimidine-rich binding(GO:0097158) |
| 1.6 | 6.2 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518) |
| 1.5 | 6.1 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 1.4 | 4.3 | GO:0016429 | tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 1.4 | 5.8 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 1.4 | 11.3 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 1.3 | 5.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 1.3 | 58.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 1.3 | 20.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 1.2 | 12.3 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.0 | 6.1 | GO:0046979 | TAP2 binding(GO:0046979) |
| 1.0 | 10.0 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 1.0 | 7.9 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 1.0 | 46.6 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.9 | 10.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.9 | 24.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.9 | 40.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.8 | 9.9 | GO:0031386 | protein tag(GO:0031386) |
| 0.8 | 6.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.8 | 8.1 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.8 | 13.8 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.8 | 3.9 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.7 | 7.5 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.7 | 9.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.7 | 2.0 | GO:0031762 | alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896) |
| 0.6 | 16.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.6 | 10.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.6 | 2.9 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.6 | 6.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.6 | 5.6 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.6 | 6.7 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.5 | 16.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.5 | 1.5 | GO:1990404 | protein ADP-ribosylase activity(GO:1990404) |
| 0.5 | 23.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.5 | 21.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.5 | 3.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.5 | 12.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.5 | 11.9 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 2.7 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.4 | 9.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.4 | 12.8 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.4 | 3.4 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
| 0.4 | 8.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.3 | 4.9 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.3 | 4.2 | GO:0001164 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.3 | 10.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.3 | 2.8 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.3 | 4.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.3 | 9.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.3 | 5.9 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.3 | 11.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 2.7 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.2 | 4.2 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.2 | 17.0 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 2.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 5.2 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 4.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 38.4 | GO:0003823 | antigen binding(GO:0003823) |
| 0.2 | 29.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.2 | 0.7 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.2 | 1.2 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.2 | 8.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 2.8 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.2 | 1.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 1.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 2.6 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 4.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 1.9 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.6 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 1.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 17.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 1.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 37.0 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 9.3 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.1 | 27.8 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 0.6 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 11.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 4.8 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 0.6 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.1 | 2.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 9.4 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.4 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.0 | 0.3 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.0 | 4.0 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.0 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 7.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.3 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 1.9 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 3.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.9 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 5.9 | GO:0016887 | ATPase activity(GO:0016887) |
| 0.0 | 0.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 1.8 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 1.3 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.8 | GO:0050661 | NADP binding(GO:0050661) |
| 0.0 | 0.8 | GO:0051087 | chaperone binding(GO:0051087) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 19.5 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 1.9 | 77.7 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 1.4 | 80.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 1.1 | 24.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.9 | 28.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.8 | 29.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.8 | 56.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.7 | 35.9 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.7 | 26.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.7 | 36.1 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.6 | 17.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.6 | 11.3 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.6 | 14.7 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.4 | 1.2 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.4 | 26.3 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.4 | 10.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.4 | 28.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.3 | 18.7 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.2 | 6.8 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 6.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.2 | 6.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.2 | 11.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 5.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 10.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 8.7 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 2.0 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 1.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 3.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 6.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.8 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.3 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 4.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.7 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 1.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 4.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.4 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 52.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 1.6 | 10.9 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 1.5 | 1.5 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 1.4 | 13.8 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 1.3 | 47.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.1 | 23.2 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 1.0 | 47.4 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 1.0 | 42.2 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.9 | 12.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.9 | 17.0 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.8 | 17.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.7 | 16.1 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.7 | 23.9 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.7 | 32.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.5 | 20.8 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.5 | 17.7 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.5 | 11.3 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.4 | 11.3 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.4 | 34.3 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.4 | 26.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.4 | 4.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.4 | 12.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 8.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 6.4 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 7.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 5.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 4.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 3.8 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.2 | 5.0 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.2 | 22.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 0.5 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.2 | 4.2 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.2 | 6.4 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.2 | 1.7 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 2.8 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.1 | 3.9 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 8.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 5.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 4.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 2.0 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 2.5 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.8 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 1.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 1.3 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 3.6 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.3 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 3.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 4.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.2 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |