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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for RELA

Z-value: 0.42

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430554_654305790.575.2e-20Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_35873856 32.56 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr17_-_4852332 26.02 ENST00000572383.1
PFN1
profilin 1
chr6_+_138188551 24.43 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_174256276 23.85 ENST00000296503.5
HMGB2
high mobility group box 2
chr5_-_150466692 20.21 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr5_-_150460914 20.08 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188224 17.83 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr6_-_30712313 17.57 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr5_-_150460539 16.14 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr11_+_102188272 15.50 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr4_+_74735102 15.24 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr22_-_37640277 14.81 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr7_-_93520259 14.45 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr1_-_209825674 14.16 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr6_-_31550192 14.11 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr4_+_103422471 14.02 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_-_58345569 13.17 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr4_-_103749179 13.16 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_74964904 13.09 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr6_+_32605195 13.01 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_41725088 12.55 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr10_+_104154229 12.24 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_103749205 12.20 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr18_+_3252265 11.88 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr9_+_36572851 11.63 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr6_+_29691198 11.41 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691056 11.05 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr5_+_82767284 11.03 ENST00000265077.3
VCAN
versican
chr1_+_155657737 10.80 ENST00000471642.2
ENST00000471214.1
DAP3
death associated protein 3
chr6_+_32605134 10.65 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr6_+_29910301 10.51 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr14_-_24616426 10.49 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr7_-_93520191 10.46 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr9_-_125667494 10.42 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chr22_-_37640456 10.03 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_9913489 9.56 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr19_-_6591113 9.48 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr3_+_157154578 9.33 ENST00000295927.3
PTX3
pentraxin 3, long
chr21_+_34775772 9.22 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr15_+_52311398 9.14 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr17_+_16318909 9.12 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_-_32403903 9.03 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr13_+_37581115 8.75 ENST00000481013.1
EXOSC8
exosome component 8
chr1_-_65432171 8.66 ENST00000342505.4
JAK1
Janus kinase 1
chr21_+_34775698 8.63 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_16318850 8.44 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr19_-_50143452 8.42 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr17_+_34900737 8.38 ENST00000304718.4
ENST00000485685.2
GGNBP2
gametogenetin binding protein 2
chr20_+_1115821 8.26 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr4_-_40631859 8.24 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr6_-_17706618 8.21 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr4_-_185395672 8.14 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr17_-_7590745 7.99 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr1_-_1822495 7.94 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr21_+_34775181 7.85 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr20_-_2451395 7.82 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr12_-_54653313 7.63 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr4_+_41614720 7.58 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr16_+_50776021 7.48 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr1_+_44870866 7.36 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr14_+_103589789 7.26 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr8_-_103668114 7.13 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr7_+_22766766 7.03 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr2_+_228678550 6.78 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_186649543 6.78 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_143078652 6.70 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr10_-_43904235 6.63 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_+_161993412 6.63 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr7_-_16844611 6.51 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr5_+_177019159 6.42 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr19_+_45504688 6.36 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr10_+_22605374 6.31 ENST00000448361.1
COMMD3
COMM domain containing 3
chr4_-_103749313 6.07 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_113249678 6.02 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr9_-_127952032 6.00 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr1_-_209824643 5.93 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr1_-_113249734 5.81 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr19_+_41725140 5.79 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr1_-_94079648 5.79 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr14_-_69446034 5.64 ENST00000193403.6
ACTN1
actinin, alpha 1
chr11_-_6633799 5.62 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr4_+_140222609 5.62 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_205744574 5.56 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr6_-_32636145 5.38 ENST00000399084.1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr10_+_104155450 5.28 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_+_19798964 5.26 ENST00000527559.2
NAV2
neuron navigator 2
chr1_+_26869597 5.26 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_-_127952187 5.26 ENST00000451402.1
ENST00000415905.1
PPP6C
protein phosphatase 6, catalytic subunit
chr10_-_102089729 5.18 ENST00000465680.2
PKD2L1
polycystic kidney disease 2-like 1
chr4_-_103749105 5.18 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr2_-_89442621 5.17 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr4_-_103748880 5.09 ENST00000453744.2
ENST00000349311.8
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_36615051 5.09 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr16_-_28223166 5.05 ENST00000304658.5
XPO6
exportin 6
chr1_+_179050512 5.02 ENST00000367627.3
TOR3A
torsin family 3, member A
chr12_-_57023995 4.87 ENST00000549884.1
ENST00000546695.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr22_-_28315115 4.84 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr18_-_12884259 4.82 ENST00000353319.4
ENST00000327283.3
PTPN2
protein tyrosine phosphatase, non-receptor type 2
chr10_+_89419370 4.81 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr19_+_45251804 4.76 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr5_-_149792295 4.66 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr1_-_36615065 4.64 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr11_-_72853091 4.62 ENST00000311172.7
ENST00000409314.1
FCHSD2
FCH and double SH3 domains 2
chr11_+_19799327 4.54 ENST00000540292.1
NAV2
neuron navigator 2
chr17_+_21191341 4.52 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr11_+_6624955 4.50 ENST00000299421.4
ENST00000537806.1
ILK
integrin-linked kinase
chr1_-_44818599 4.44 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr7_-_24797546 4.43 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr10_+_22605304 4.43 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr19_+_42364460 4.34 ENST00000593863.1
RPS19
ribosomal protein S19
chr1_-_54304212 4.32 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr16_-_28222797 4.31 ENST00000569951.1
ENST00000565698.1
XPO6
exportin 6
chr11_+_6625046 4.30 ENST00000396751.2
ILK
integrin-linked kinase
chr6_+_30297306 4.28 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr4_-_74864386 4.27 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_-_205744205 4.14 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr3_+_184033135 4.10 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr2_+_208394455 4.09 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr7_-_24797032 4.08 ENST00000409970.1
ENST00000409775.3
DFNA5
deafness, autosomal dominant 5
chr7_-_100881109 4.07 ENST00000308344.5
CLDN15
claudin 15
chr7_-_47579188 4.07 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3
tensin 3
chr22_-_37545972 3.90 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr12_-_57504069 3.88 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr20_-_43977055 3.86 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr3_+_9439400 3.62 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SETD5
SET domain containing 5
chr14_+_103243813 3.62 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr12_+_7055631 3.60 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr22_+_41347363 3.51 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr6_-_74231303 3.45 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chrX_+_117861535 3.40 ENST00000371666.3
ENST00000371642.1
IL13RA1
interleukin 13 receptor, alpha 1
chr1_+_235490659 3.37 ENST00000488594.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr2_-_191885686 3.35 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_+_9439579 3.29 ENST00000406341.1
SETD5
SET domain containing 5
chr1_-_54303934 3.24 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr15_+_85923797 3.22 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chrX_-_131352152 3.16 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr11_-_3862206 3.11 ENST00000351018.4
RHOG
ras homolog family member G
chr1_-_153935983 3.09 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr4_-_74904398 3.04 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr6_-_29527702 2.99 ENST00000377050.4
UBD
ubiquitin D
chr1_-_153935938 2.96 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chrX_-_48755030 2.84 ENST00000490755.2
ENST00000465150.2
ENST00000495490.2
TIMM17B
translocase of inner mitochondrial membrane 17 homolog B (yeast)
chr1_+_101185290 2.75 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1
vascular cell adhesion molecule 1
chr6_+_31540056 2.74 ENST00000418386.2
LTA
lymphotoxin alpha
chr2_-_203776864 2.73 ENST00000261015.4
WDR12
WD repeat domain 12
chr3_+_53195136 2.73 ENST00000394729.2
ENST00000330452.3
PRKCD
protein kinase C, delta
chr5_+_14143728 2.71 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr19_-_7766991 2.69 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr2_+_208394616 2.69 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr3_-_158390282 2.66 ENST00000264265.3
LXN
latexin
chr4_-_187644930 2.65 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr4_+_74702214 2.61 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr6_-_74230741 2.61 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr19_+_42381337 2.58 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr19_+_42364313 2.45 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr17_-_61777090 2.45 ENST00000578061.1
LIMD2
LIM domain containing 2
chr19_+_2476116 2.43 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr9_-_125667618 2.41 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr19_+_42381173 2.36 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr12_+_49761224 2.34 ENST00000553127.1
ENST00000321898.6
SPATS2
spermatogenesis associated, serine-rich 2
chr5_+_139781393 2.27 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1
ankyrin repeat and KH domain containing 1
chr2_-_136743169 2.26 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr4_+_169418195 2.25 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr12_-_76425368 2.25 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_+_63833261 2.23 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr5_+_112312416 2.22 ENST00000389063.2
DCP2
decapping mRNA 2
chrX_-_48827976 2.18 ENST00000218176.3
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_155658085 2.15 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr1_-_27216729 2.12 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr2_+_44396000 2.09 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr2_+_233925064 2.08 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr1_+_8021954 2.05 ENST00000377491.1
ENST00000377488.1
PARK7
parkinson protein 7
chr10_-_102090243 2.01 ENST00000338519.3
ENST00000353274.3
ENST00000318222.3
PKD2L1
polycystic kidney disease 2-like 1
chr4_-_76928641 1.99 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr12_+_49761273 1.99 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
SPATS2
spermatogenesis associated, serine-rich 2
chr2_+_162016916 1.99 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr5_+_139781445 1.98 ENST00000532219.1
ENST00000394722.3
ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr11_+_18287721 1.98 ENST00000356524.4
SAA1
serum amyloid A1
chrX_-_119709637 1.95 ENST00000404115.3
CUL4B
cullin 4B
chr15_+_57884199 1.95 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GCOM1
MYZAP
POLR2M
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr15_+_57884086 1.95 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr12_+_53662073 1.93 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr11_-_44331679 1.86 ENST00000329255.3
ALX4
ALX homeobox 4
chr14_+_96968707 1.83 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr1_-_54303949 1.82 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr11_+_18287801 1.81 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr2_+_208394794 1.79 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr1_+_221054584 1.78 ENST00000549319.1
HLX
H2.0-like homeobox
chrX_+_48755183 1.77 ENST00000376563.1
ENST00000376566.4
PQBP1
polyglutamine binding protein 1
chr1_-_151319710 1.76 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr7_+_134464376 1.75 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr14_+_24439148 1.72 ENST00000543805.1
ENST00000534993.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr19_+_42363917 1.71 ENST00000598742.1
RPS19
ribosomal protein S19
chr4_+_41614909 1.71 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr20_-_36156293 1.71 ENST00000373537.2
ENST00000414542.2
BLCAP
bladder cancer associated protein
chr12_-_28124903 1.71 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr11_+_10476851 1.68 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr12_-_6716534 1.68 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4
chromodomain helicase DNA binding protein 4
chr12_-_6716569 1.64 ENST00000544040.1
ENST00000545942.1
CHD4
chromodomain helicase DNA binding protein 4
chr15_-_51914810 1.58 ENST00000543779.2
ENST00000449909.3
DMXL2
Dmx-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
18.8 56.4 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
9.5 57.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
5.6 22.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
4.3 12.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
3.7 33.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
3.3 33.0 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
3.1 9.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
3.1 28.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
3.1 18.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
2.8 8.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
2.7 8.0 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
2.6 26.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
2.5 9.8 GO:0021564 vagus nerve development(GO:0021564)
2.3 7.0 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
2.3 6.8 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
2.3 24.8 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
2.2 8.8 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.1 8.5 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.1 21.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.1 16.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
2.0 13.9 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
2.0 11.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.9 9.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
1.7 6.8 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of platelet-derived growth factor production(GO:0090362) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.6 6.5 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.6 6.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.6 4.7 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.4 1.4 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.4 8.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.4 8.2 GO:0016554 cytidine to uridine editing(GO:0016554)
1.3 34.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
1.3 1.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.2 3.7 GO:1990108 protein linear deubiquitination(GO:1990108)
1.2 4.8 GO:0000103 sulfate assimilation(GO:0000103)
1.1 3.4 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
1.1 3.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
1.1 5.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.0 7.2 GO:0050915 sensory perception of sour taste(GO:0050915)
1.0 3.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.9 5.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9 29.0 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.9 41.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.9 3.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 5.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.8 3.3 GO:0072553 terminal button organization(GO:0072553)
0.8 2.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8 3.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.8 4.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.7 24.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.7 2.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7 2.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 20.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.7 2.7 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.7 7.3 GO:0051601 exocyst localization(GO:0051601)
0.7 2.0 GO:0051685 maintenance of ER location(GO:0051685)
0.6 8.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.6 3.0 GO:0070842 aggresome assembly(GO:0070842)
0.6 1.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.6 1.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.6 4.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.5 10.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.5 4.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.5 2.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 5.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.5 7.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.5 2.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 11.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 39.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.4 1.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 5.6 GO:0051639 actin filament network formation(GO:0051639)
0.4 3.5 GO:0010265 SCF complex assembly(GO:0010265)
0.3 2.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.3 10.0 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.3 6.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.3 7.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 4.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.3 1.7 GO:0006196 AMP catabolic process(GO:0006196)
0.3 1.4 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.3 6.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 3.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 17.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 1.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.3 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.2 2.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 2.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 5.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 19.8 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 3.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 2.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 11.6 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 18.8 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.2 1.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 5.2 GO:0003094 glomerular filtration(GO:0003094)
0.2 9.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 2.0 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 8.5 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.1 3.1 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 12.0 GO:0070527 platelet aggregation(GO:0070527)
0.1 10.8 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 4.3 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 2.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.7 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 4.1 GO:0048286 lung alveolus development(GO:0048286)
0.1 2.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 2.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 6.5 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 4.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 4.9 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 1.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 1.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.1 4.3 GO:0006611 protein export from nucleus(GO:0006611)
0.1 4.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 13.7 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.1 2.6 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 7.1 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 8.4 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.1 15.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.2 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 4.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.8 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 6.1 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 2.2 GO:0044839 cell cycle G2/M phase transition(GO:0044839)
0.0 1.8 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0048535 lymph node development(GO:0048535)
0.0 5.0 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 1.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 72.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
3.1 9.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
3.0 33.0 GO:0042612 MHC class I protein complex(GO:0042612)
2.5 20.1 GO:0005610 laminin-5 complex(GO:0005610)
2.0 13.7 GO:0032584 growth cone membrane(GO:0032584)
1.7 7.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.7 10.5 GO:0008537 proteasome activator complex(GO:0008537)
1.7 5.2 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.6 33.7 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
1.2 18.3 GO:0033643 host cell part(GO:0033643)
1.2 3.5 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.0 7.8 GO:0071204 U7 snRNP(GO:0005683) histone pre-mRNA 3'end processing complex(GO:0071204)
1.0 4.9 GO:0033553 rDNA heterochromatin(GO:0033553)
0.9 2.7 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.9 2.7 GO:0043291 RAVE complex(GO:0043291)
0.9 9.8 GO:0005614 interstitial matrix(GO:0005614)
0.9 1.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.8 9.7 GO:0030008 TRAPP complex(GO:0030008)
0.8 5.6 GO:0031415 NatA complex(GO:0031415)
0.8 8.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.7 5.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.7 4.9 GO:0019815 B cell receptor complex(GO:0019815)
0.7 6.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.7 8.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.6 5.6 GO:0000125 PCAF complex(GO:0000125)
0.6 6.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 7.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 7.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 7.3 GO:0000145 exocyst(GO:0000145)
0.5 2.7 GO:0070545 PeBoW complex(GO:0070545)
0.4 3.0 GO:0030478 actin cap(GO:0030478)
0.4 10.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 9.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.4 1.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 5.6 GO:0005916 fascia adherens(GO:0005916)
0.4 1.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 11.8 GO:0032420 stereocilium(GO:0032420)
0.3 3.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 24.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 14.7 GO:0002102 podosome(GO:0002102)
0.3 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 21.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.3 8.3 GO:0005839 proteasome core complex(GO:0005839)
0.2 2.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 4.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 3.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 6.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 8.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 14.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 3.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 11.9 GO:0016459 myosin complex(GO:0016459)
0.1 8.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 14.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 19.7 GO:0072562 blood microparticle(GO:0072562)
0.1 12.4 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 6.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 5.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 20.2 GO:0000793 condensed chromosome(GO:0000793)
0.1 3.7 GO:0097542 ciliary tip(GO:0097542)
0.1 1.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 4.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 36.4 GO:0010008 endosome membrane(GO:0010008)
0.1 29.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 3.0 GO:0016235 aggresome(GO:0016235)
0.1 5.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 9.0 GO:0005769 early endosome(GO:0005769)
0.1 6.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 27.3 GO:0005925 focal adhesion(GO:0005925)
0.1 4.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 20.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 0.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 4.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 16.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 3.9 GO:0031674 I band(GO:0031674)
0.0 10.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 6.9 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 4.7 GO:0005739 mitochondrion(GO:0005739)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.1 GO:0030425 dendrite(GO:0030425)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 23.8 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
5.1 25.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
3.7 22.5 GO:0046979 TAP2 binding(GO:0046979)
2.8 28.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
2.3 6.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
2.3 9.0 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
2.2 26.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
2.1 29.0 GO:0032395 MHC class II receptor activity(GO:0032395)
2.0 7.9 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.7 6.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
1.6 26.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.6 4.8 GO:0097677 STAT family protein binding(GO:0097677)
1.6 4.8 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.6 7.8 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.5 10.5 GO:0061133 endopeptidase activator activity(GO:0061133)
1.4 8.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.2 9.3 GO:0001849 complement component C1q binding(GO:0001849)
1.2 4.7 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 18.3 GO:0032036 myosin heavy chain binding(GO:0032036)
1.1 56.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
1.1 40.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
1.0 9.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.9 41.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.9 8.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.9 5.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.8 3.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.8 38.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.8 7.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.7 2.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.7 3.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 3.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.7 3.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.6 30.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 10.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.6 11.3 GO:0070628 proteasome binding(GO:0070628)
0.5 9.1 GO:0004707 MAP kinase activity(GO:0004707)
0.5 7.2 GO:0008527 taste receptor activity(GO:0008527)
0.5 9.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 3.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 5.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.4 1.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.4 3.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 11.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 2.7 GO:0019863 IgE binding(GO:0019863)
0.3 5.6 GO:0017166 vinculin binding(GO:0017166)
0.3 4.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 6.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 1.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 4.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 10.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 6.5 GO:0002162 dystroglycan binding(GO:0002162)
0.3 2.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 16.2 GO:0042805 actinin binding(GO:0042805)
0.3 2.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 4.9 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 23.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 8.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 2.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 1.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 6.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 2.4 GO:0008199 ferric iron binding(GO:0008199)
0.2 6.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 9.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 12.7 GO:0019003 GDP binding(GO:0019003)
0.2 2.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 6.2 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 3.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 5.6 GO:0004527 exonuclease activity(GO:0004527)
0.1 2.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 14.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 14.8 GO:0000149 SNARE binding(GO:0000149)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 28.6 GO:0003924 GTPase activity(GO:0003924)
0.1 3.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 7.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 1.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 3.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 5.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 11.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 6.4 GO:0001047 core promoter binding(GO:0001047)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 5.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 9.8 GO:0008201 heparin binding(GO:0008201)
0.1 5.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 8.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 10.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor binding(GO:0005172) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 1.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 4.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0003682 chromatin binding(GO:0003682)
0.0 2.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 111.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
1.2 12.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
1.1 46.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.9 20.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.7 10.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.6 16.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 32.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.6 20.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 24.4 PID IL23 PATHWAY IL23-mediated signaling events
0.5 18.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.5 7.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 26.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.4 8.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 6.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.4 22.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 5.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.3 9.3 ST ADRENERGIC Adrenergic Pathway
0.3 11.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 9.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 10.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 18.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 1.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 10.4 PID BCR 5PATHWAY BCR signaling pathway
0.2 4.8 PID IFNG PATHWAY IFN-gamma pathway
0.2 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.2 6.2 PID RAS PATHWAY Regulation of Ras family activation
0.2 5.6 PID MYC PATHWAY C-MYC pathway
0.1 7.6 PID AURORA B PATHWAY Aurora B signaling
0.1 5.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 4.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 33.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.9 46.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.8 26.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
1.4 72.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.2 23.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.1 16.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.0 23.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.0 8.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9 44.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.8 34.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.8 4.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.7 7.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 26.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 34.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 13.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.5 7.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 14.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4 3.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.4 6.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 26.7 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.4 9.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 1.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 7.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 2.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 10.4 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.2 8.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 4.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 4.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.8 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 5.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 8.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 4.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 5.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 3.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 4.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 6.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 4.7 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 4.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 2.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 4.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters