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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for RFX3_RFX2

Z-value: 1.78

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.11 regulatory factor X3
ENSG00000087903.8 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110474_61105510.601.8e-22Click!
RFX3hg19_v2_chr9_-_3525968_35260160.385.3e-09Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_48693955 132.33 ENST00000218230.5
proprotein convertase subtilisin/kexin type 1 inhibitor
chr15_+_43803143 112.16 ENST00000382031.1
microtubule-associated protein 1A
chr3_-_58563094 103.82 ENST00000464064.1
family with sequence similarity 107, member A
chr1_-_204380919 98.27 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr16_+_8806800 98.10 ENST00000561870.1
ENST00000396600.2
4-aminobutyrate aminotransferase
chr2_-_175869936 81.69 ENST00000409900.3
chimerin 1
chr19_-_57352064 75.20 ENST00000326441.9
ENST00000593695.1
ENST00000599577.1
ENST00000594389.1
ENST00000423103.2
ENST00000598410.1
ENST00000593711.1
ENST00000391708.3
ENST00000221722.5
ENST00000599935.1
paternally expressed 3
zinc finger, imprinted 2
chr11_+_133938820 74.99 ENST00000299106.4
ENST00000529443.2
junctional adhesion molecule 3
chr15_+_71184931 73.56 ENST00000560369.1
ENST00000260382.5
leucine rich repeat containing 49
chr2_-_175870085 71.36 ENST00000409156.3
chimerin 1
chr19_-_46974741 69.77 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr11_+_133938955 69.72 ENST00000534549.1
ENST00000441717.3
junctional adhesion molecule 3
chr11_-_62473706 69.64 ENST00000403550.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_31391381 67.77 ENST00000465995.1
ENST00000536040.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr19_-_55690758 67.56 ENST00000590851.1
synaptotagmin V
chr19_-_46974664 67.52 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr19_-_58609570 64.72 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
zinc finger and SCAN domain containing 18
chr14_-_74181106 63.05 ENST00000316836.3
paraneoplastic Ma antigen 1
chr19_+_35630022 61.89 ENST00000589209.1
FXYD domain containing ion transport regulator 1
chr19_+_35630926 60.84 ENST00000588081.1
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr15_+_71185148 60.27 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr3_-_149688896 58.66 ENST00000239940.7
profilin 2
chr11_-_62473776 58.55 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_98290087 57.51 ENST00000322128.3
TSPY-like 5
chr5_-_11588907 56.61 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr16_+_84178874 54.78 ENST00000378553.5
dynein, axonemal, assembly factor 1
chr16_+_19729586 54.58 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQ motif containing K
chr16_+_4784458 53.71 ENST00000590191.1
chromosome 16 open reading frame 71
chr7_+_102715315 52.45 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
armadillo repeat containing 10
chr16_+_58283814 52.09 ENST00000443128.2
ENST00000219299.4
coiled-coil domain containing 113
chr6_-_116575226 51.74 ENST00000420283.1
TSPY-like 4
chr19_+_35630628 51.44 ENST00000588715.1
ENST00000588607.1
FXYD domain containing ion transport regulator 1
chr20_-_48532019 51.21 ENST00000289431.5
spermatogenesis associated 2
chr5_-_11589131 51.18 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr2_+_27193480 51.10 ENST00000233121.2
ENST00000405074.3
microtubule-associated protein, RP/EB family, member 3
chr13_-_30881621 50.55 ENST00000380615.3
katanin p60 subunit A-like 1
chr1_-_21978312 48.95 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr12_-_54978086 47.97 ENST00000553113.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr10_-_135150367 47.88 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
calcyon neuron-specific vesicular protein
chr4_+_128554081 45.66 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr19_+_35634146 45.30 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD domain containing ion transport regulator 7
chr4_-_87281196 44.14 ENST00000359221.3
mitogen-activated protein kinase 10
chrX_+_129473859 44.13 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr16_+_67840668 44.00 ENST00000415766.3
translin-associated factor X interacting protein 1
chr10_-_120514720 43.84 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr1_-_48937682 43.73 ENST00000371843.3
spermatogenesis associated 6
chr11_-_64885111 41.44 ENST00000528598.1
ENST00000310597.4
zinc finger, HIT-type containing 2
chr1_-_109584716 40.50 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WD repeat domain 47
chr1_+_38022513 40.44 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr17_-_74137374 40.33 ENST00000322957.6
forkhead box J1
chr1_+_183605200 40.27 ENST00000304685.4
ral guanine nucleotide dissociation stimulator-like 1
chr1_-_48937821 39.81 ENST00000396199.3
spermatogenesis associated 6
chr19_+_56652556 39.73 ENST00000337080.3
zinc finger protein 444
chr7_-_45128472 39.59 ENST00000490531.2
NAC alpha domain containing
chr2_+_55746746 39.48 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
coiled-coil domain containing 104
chr7_-_129845188 39.42 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
transmembrane protein 209
chr20_+_44509857 39.38 ENST00000372523.1
ENST00000372520.1
zinc finger, SWIM-type containing 1
chr1_-_48937838 39.14 ENST00000371847.3
spermatogenesis associated 6
chr17_-_64187973 38.94 ENST00000583358.1
ENST00000392769.2
centrosomal protein 112kDa
chr17_-_8079648 38.85 ENST00000449985.2
ENST00000532998.1
ENST00000437139.2
ENST00000533070.1
ENST00000316425.5
transmembrane protein 107
chr2_-_44588624 38.76 ENST00000438314.1
ENST00000409936.1
prolyl endopeptidase-like
chr2_+_79740118 38.63 ENST00000496558.1
ENST00000451966.1
catenin (cadherin-associated protein), alpha 2
chr6_-_35109080 38.32 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
t-complex 11, testis-specific
chr2_-_2334888 38.21 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr11_-_116968987 38.15 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr8_+_21912328 38.07 ENST00000432128.1
ENST00000443491.2
ENST00000517600.1
ENST00000523782.2
dematin actin binding protein
chr4_-_87281224 37.92 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr6_+_31783291 37.81 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr22_+_38453378 37.77 ENST00000437453.1
ENST00000356976.3
protein interacting with PRKCA 1
chr19_+_10217364 37.34 ENST00000430370.1
peter pan homolog (Drosophila)
chr8_+_42010464 37.14 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
adaptor-related protein complex 3, mu 2 subunit
chr3_-_50383096 37.08 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chr7_+_99699280 37.05 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr17_-_64188177 36.98 ENST00000535342.2
centrosomal protein 112kDa
chr1_-_109584768 36.97 ENST00000357672.3
WD repeat domain 47
chr1_-_15735925 36.96 ENST00000427824.1
RP3-467K16.4
chr11_+_46958248 36.28 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
chromosome 11 open reading frame 49
chr8_+_85618155 36.25 ENST00000523850.1
ENST00000521376.1
RALY RNA binding protein-like
chr19_+_5681011 35.98 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_10217270 35.67 ENST00000446223.1
peter pan homolog (Drosophila)
chr7_-_129845313 35.60 ENST00000397622.2
transmembrane protein 209
chr2_-_44588694 35.51 ENST00000409957.1
prolyl endopeptidase-like
chr5_-_74062930 35.44 ENST00000509430.1
ENST00000345239.2
ENST00000427854.2
ENST00000506778.1
G elongation factor, mitochondrial 2
chr22_+_38453207 34.68 ENST00000404072.3
ENST00000424694.1
protein interacting with PRKCA 1
chr10_+_12171636 34.67 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
Sec61 alpha 2 subunit (S. cerevisiae)
chr16_+_67840986 34.59 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr6_-_35109145 34.40 ENST00000373974.4
ENST00000244645.3
t-complex 11, testis-specific
chr7_+_99699179 34.13 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr2_-_44588679 33.99 ENST00000409411.1
prolyl endopeptidase-like
chr1_-_169396646 33.99 ENST00000367806.3
coiled-coil domain containing 181
chr12_+_7014064 33.97 ENST00000443597.2
leucine rich repeat containing 23
chr19_-_56826157 33.96 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr19_-_4457776 33.79 ENST00000301281.6
UBX domain protein 6
chr6_-_32145861 33.55 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr7_-_51384451 33.36 ENST00000441453.1
ENST00000265136.7
ENST00000395542.2
ENST00000395540.2
cordon-bleu WH2 repeat protein
chr14_-_77787198 33.31 ENST00000261534.4
protein-O-mannosyltransferase 2
chr5_-_132073210 33.25 ENST00000378735.1
ENST00000378746.4
kinesin family member 3A
chr7_-_100965011 33.08 ENST00000498704.2
ENST00000517481.1
ENST00000437644.2
ENST00000315322.4
RAB, member RAS oncogene family-like 5
chr1_-_109584608 32.77 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr10_+_134145614 32.60 ENST00000368615.3
ENST00000392638.2
ENST00000344079.5
ENST00000356571.4
ENST00000368614.3
leucine rich repeat containing 27
chr3_+_196439170 32.44 ENST00000392391.3
ENST00000314118.4
phosphatidylinositol glycan anchor biosynthesis, class X
chr1_+_245133278 32.38 ENST00000366522.2
EF-hand calcium binding domain 2
chr12_+_70132632 31.91 ENST00000378815.6
ENST00000483530.2
ENST00000325555.9
RAB3A interacting protein
chr1_-_156217822 31.88 ENST00000368270.1
progestin and adipoQ receptor family member VI
chr7_-_37026108 31.82 ENST00000396045.3
engulfment and cell motility 1
chr2_-_44588893 31.40 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
prolyl endopeptidase-like
chr1_-_156217875 31.22 ENST00000292291.5
progestin and adipoQ receptor family member VI
chr11_-_115375107 31.21 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chr11_-_132813566 30.84 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr1_-_156217829 30.81 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
progestin and adipoQ receptor family member VI
chr1_-_6240183 30.80 ENST00000262450.3
ENST00000378021.1
chromodomain helicase DNA binding protein 5
chr3_+_38080691 30.65 ENST00000308059.6
ENST00000346219.3
ENST00000452631.2
deleted in lung and esophageal cancer 1
chr22_-_43485381 30.58 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
tubulin tyrosine ligase-like family, member 1
chr12_+_7014126 30.35 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr9_+_135754263 30.07 ENST00000356311.5
ENST00000350499.6
chromosome 9 open reading frame 9
chr12_+_6930964 29.54 ENST00000382315.3
G protein-coupled receptor 162
chr6_-_31940065 29.31 ENST00000375349.3
ENST00000337523.5
decapping exoribonuclease
chr12_+_7013897 29.27 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr1_+_169337172 28.97 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
basic leucine zipper nuclear factor 1
chr11_-_66360548 28.88 ENST00000333861.3
coiled-coil domain containing 87
chr2_-_62733476 28.82 ENST00000335390.5
transmembrane protein 17
chr10_+_12171721 28.62 ENST00000379020.4
ENST00000379017.3
Sec61 alpha 2 subunit (S. cerevisiae)
chr11_+_28129795 28.46 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr22_+_23487513 28.10 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr8_+_38243821 28.09 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr4_+_114214125 28.06 ENST00000509550.1
ankyrin 2, neuronal
chr3_-_196439065 27.96 ENST00000399942.4
ENST00000409690.3
centrosomal protein 19kDa
chr1_+_244998602 27.96 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr21_+_40817749 27.85 ENST00000380637.3
ENST00000380634.1
ENST00000458295.1
ENST00000440288.2
ENST00000380631.1
SH3 domain binding glutamic acid-rich protein
chr15_+_90777424 27.64 ENST00000561433.1
ENST00000559204.1
ENST00000558291.1
GDP-D-glucose phosphorylase 1
chr20_+_62185491 27.62 ENST00000370097.1
chromosome 20 open reading frame 195
chr5_-_114505624 27.61 ENST00000513154.1
tripartite motif containing 36
chr15_-_72978490 27.50 ENST00000311755.3
HIG1 hypoxia inducible domain family, member 2B
chr2_+_173600514 27.47 ENST00000264111.6
Rap guanine nucleotide exchange factor (GEF) 4
chr22_+_30752606 27.44 ENST00000399824.2
ENST00000405659.1
ENST00000338306.3
coiled-coil domain containing 157
chr3_+_9851632 27.37 ENST00000426895.4
tubulin tyrosine ligase-like family, member 3
chr3_-_49055991 27.21 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALR anticodon binding domain containing 3
chr20_-_3762087 26.30 ENST00000379756.3
sperm flagellar 1
chr16_+_89724263 26.30 ENST00000564238.1
spermatogenesis associated 33
chr15_-_55700457 25.92 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr7_+_138916231 25.88 ENST00000473989.3
ENST00000288561.8
ubinuclein 2
chr12_+_9067327 25.83 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
polyhomeotic homolog 1 (Drosophila)
chr11_-_6426635 25.82 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr5_-_132073111 25.75 ENST00000403231.1
kinesin family member 3A
chr19_+_58962971 25.62 ENST00000336614.4
ENST00000545523.1
ENST00000599194.1
ENST00000598244.1
ENST00000599193.1
ENST00000594214.1
ENST00000391696.1
zinc finger protein 324B
chr14_+_102829300 25.45 ENST00000359520.7
tectonin beta-propeller repeat containing 2
chr1_-_169396666 25.28 ENST00000456107.1
ENST00000367805.3
coiled-coil domain containing 181
chr13_+_37005967 25.22 ENST00000440264.1
ENST00000449823.1
cyclin A1
chr1_-_40157345 25.20 ENST00000372844.3
hippocalcin like 4
chr7_+_156433573 25.11 ENST00000311822.8
ring finger protein 32
chr7_+_156433396 24.94 ENST00000432459.2
ring finger protein 32
chr20_+_43160409 24.85 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr11_-_119252425 24.80 ENST00000260187.2
ubiquitin specific peptidase 2
chr12_+_9067123 24.77 ENST00000543824.1
polyhomeotic homolog 1 (Drosophila)
chr6_-_84937314 24.58 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr1_+_180601139 24.49 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr19_+_18263928 24.45 ENST00000222254.8
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr1_-_154155675 24.21 ENST00000330188.9
ENST00000341485.5
tropomyosin 3
chr14_+_74416989 24.03 ENST00000334571.2
ENST00000554920.1
coenzyme Q6 monooxygenase
chr11_-_119252359 23.77 ENST00000455332.2
ubiquitin specific peptidase 2
chr4_+_153701081 23.77 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ADP-ribosylation factor interacting protein 1
chr2_+_173600565 23.76 ENST00000397081.3
Rap guanine nucleotide exchange factor (GEF) 4
chr11_+_66278080 23.71 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
Bardet-Biedl syndrome 1
chr1_+_15573757 23.48 ENST00000358897.4
ENST00000417793.1
ENST00000375999.3
ENST00000433640.2
forkhead-associated (FHA) phosphopeptide binding domain 1
chr21_-_37432764 23.47 ENST00000399212.1
ENST00000446166.1
SET domain containing 4
chr1_-_67390474 23.42 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WD repeat domain 78
chr21_-_37432832 23.38 ENST00000332131.4
SET domain containing 4
chr19_+_54371114 23.38 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
myeloid-associated differentiation marker
chr13_-_31736132 23.37 ENST00000429785.2
heat shock 105kDa/110kDa protein 1
chr8_-_125486755 23.37 ENST00000499418.2
ENST00000530778.1
RNF139 antisense RNA 1 (head to head)
chr1_-_154155595 23.28 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
tropomyosin 3
chr14_+_74486043 23.17 ENST00000464394.1
ENST00000394009.3
coiled-coil domain containing 176
chr15_+_42066632 23.10 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
mitogen-activated protein kinase binding protein 1
chr1_-_114301755 22.95 ENST00000393357.2
ENST00000369596.2
ENST00000446739.1
putative homeodomain transcription factor 1
chr4_-_186125077 22.91 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
chr1_-_86861936 22.86 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
outer dense fiber of sperm tails 2-like
chr9_-_35812236 22.81 ENST00000340291.2
sperm associated antigen 8
chr19_+_10527449 22.80 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr7_+_156433461 22.75 ENST00000317955.5
ENST00000405335.1
ring finger protein 32
chr19_+_38826477 22.56 ENST00000409410.2
ENST00000215069.4
catsper channel auxiliary subunit gamma
chr7_-_44229022 22.54 ENST00000403799.3
glucokinase (hexokinase 4)
chr17_-_80656528 22.20 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B, member RAS oncogene family
chr4_+_56814968 22.18 ENST00000422247.2
centrosomal protein 135kDa
chr2_+_27070964 22.04 ENST00000288699.6
dihydropyrimidinase-like 5
chr10_-_99393242 22.02 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chr3_+_49027308 21.96 ENST00000383729.4
ENST00000343546.4
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr20_+_43160458 21.95 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr13_+_42846272 21.89 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chrX_+_135251783 21.82 ENST00000394153.2
four and a half LIM domains 1
chr11_-_85565906 21.81 ENST00000544076.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
chr19_+_1450112 21.71 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
adenomatosis polyposis coli 2
chr10_-_104179682 21.59 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr1_+_38022572 21.52 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr19_-_4535233 21.48 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr9_+_112403088 21.48 ENST00000448454.2
paralemmin 2
chr10_-_120101804 21.42 ENST00000369183.4
ENST00000369172.4
family with sequence similarity 204, member A
chr19_-_5680499 21.42 ENST00000587589.1
chromosome 19 open reading frame 70
chr21_-_37432540 21.36 ENST00000443703.1
ENST00000399207.1
ENST00000399215.1
ENST00000442559.1
ENST00000399205.1
ENST00000429161.1
ENST00000424303.1
ENST00000399208.2
SET domain containing 4
chr4_+_113970772 21.31 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr9_+_131218336 21.20 ENST00000372814.3
outer dense fiber of sperm tails 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
32.1 192.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
29.0 116.2 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
24.2 72.7 GO:1902490 regulation of sperm capacitation(GO:1902490)
17.7 159.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
17.0 51.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
16.5 49.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
16.3 49.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
13.4 40.3 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
11.6 69.8 GO:0070560 protein secretion by platelet(GO:0070560)
11.1 122.2 GO:0036159 inner dynein arm assembly(GO:0036159)
10.9 98.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
10.4 72.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
10.3 82.1 GO:0007258 JUN phosphorylation(GO:0007258)
9.7 38.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
9.6 38.3 GO:0018094 protein polyglycylation(GO:0018094)
9.5 37.8 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
9.4 28.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
9.3 55.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
9.1 27.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
8.6 25.8 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
8.4 50.6 GO:0051013 microtubule severing(GO:0051013)
8.4 42.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
8.3 33.4 GO:0001757 somite specification(GO:0001757)
8.2 147.1 GO:0044458 motile cilium assembly(GO:0044458)
8.0 72.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
7.8 31.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
7.4 36.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
7.2 28.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
7.2 21.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
7.0 21.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
7.0 27.8 GO:0044375 regulation of peroxisome size(GO:0044375)
6.9 6.9 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
6.8 68.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
6.7 33.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
6.6 132.3 GO:0002021 response to dietary excess(GO:0002021)
6.0 18.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
5.8 23.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
5.8 23.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
5.7 40.0 GO:0007288 sperm axoneme assembly(GO:0007288)
5.6 128.2 GO:0034389 lipid particle organization(GO:0034389)
5.4 16.3 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
5.4 21.7 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
5.4 16.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
5.0 15.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
4.9 24.7 GO:0097338 response to clozapine(GO:0097338)
4.9 9.9 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
4.9 19.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
4.9 58.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
4.8 14.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
4.5 22.6 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
4.5 153.0 GO:0008045 motor neuron axon guidance(GO:0008045)
4.5 35.8 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
4.4 35.4 GO:0032790 ribosome disassembly(GO:0032790)
4.4 30.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
4.3 13.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
4.3 12.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
4.2 33.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
4.2 21.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
3.9 31.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
3.6 10.9 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
3.6 139.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
3.6 28.5 GO:0070475 rRNA base methylation(GO:0070475)
3.5 24.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
3.4 78.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
3.3 19.8 GO:0048549 positive regulation of pinocytosis(GO:0048549)
3.2 22.5 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
3.1 12.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
3.1 34.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
3.0 48.6 GO:0045475 locomotor rhythm(GO:0045475)
2.9 20.5 GO:0006572 tyrosine catabolic process(GO:0006572)
2.8 71.2 GO:0006895 Golgi to endosome transport(GO:0006895)
2.8 8.5 GO:1900060 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
2.7 16.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
2.7 65.1 GO:0007141 male meiosis I(GO:0007141)
2.6 7.9 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
2.6 34.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
2.5 37.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
2.4 21.9 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
2.4 75.9 GO:0097120 receptor localization to synapse(GO:0097120)
2.3 22.9 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
2.2 33.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
2.2 17.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
2.2 21.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
2.2 32.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
2.1 8.4 GO:0008089 anterograde axonal transport(GO:0008089)
2.1 29.3 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
2.1 16.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
1.9 5.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
1.9 20.9 GO:0015886 heme transport(GO:0015886)
1.9 24.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
1.8 34.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
1.8 3.5 GO:0071426 ribonucleoprotein complex export from nucleus(GO:0071426)
1.8 31.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.8 57.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.7 26.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.7 13.9 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.7 17.3 GO:0015889 cobalamin transport(GO:0015889)
1.7 53.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.6 6.5 GO:0042360 vitamin E metabolic process(GO:0042360)
1.6 4.9 GO:1904504 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.6 4.9 GO:1990523 bone regeneration(GO:1990523)
1.6 20.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.6 23.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
1.5 38.2 GO:0048665 neuron fate specification(GO:0048665)
1.5 3.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
1.5 94.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
1.4 5.7 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.4 8.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.4 5.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
1.4 10.9 GO:0070995 NADPH oxidation(GO:0070995)
1.4 52.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
1.3 15.5 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
1.3 12.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.3 16.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.2 55.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
1.2 18.8 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
1.2 3.5 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) negative regulation by host of viral genome replication(GO:0044828)
1.1 10.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.1 57.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
1.1 10.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.1 21.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
1.1 31.8 GO:0016601 Rac protein signal transduction(GO:0016601)
1.1 4.3 GO:2000232 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
1.1 8.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
1.0 3.1 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of adrenergic receptor signaling pathway(GO:0071878) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.0 33.0 GO:0007340 acrosome reaction(GO:0007340)
1.0 60.3 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
1.0 16.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
1.0 21.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.9 52.7 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.9 24.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.9 15.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.9 17.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.9 47.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.9 9.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9 0.9 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.9 46.7 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.9 50.5 GO:0009060 aerobic respiration(GO:0009060)
0.8 33.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.8 30.8 GO:0008038 neuron recognition(GO:0008038)
0.8 58.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.8 2.4 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8 22.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.8 9.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.7 9.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.7 13.2 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.7 56.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.7 18.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.7 10.8 GO:0006004 fucose metabolic process(GO:0006004)
0.7 73.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.6 18.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.6 35.6 GO:0032570 response to progesterone(GO:0032570)
0.6 4.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.6 5.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.6 51.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.6 1.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 14.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.5 3.4 GO:0045007 depurination(GO:0045007)
0.5 8.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.5 12.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.5 3.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 1.8 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.5 41.0 GO:0005977 glycogen metabolic process(GO:0005977)
0.5 12.7 GO:0003091 renal water homeostasis(GO:0003091)
0.5 5.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.4 23.3 GO:0016574 histone ubiquitination(GO:0016574)
0.4 7.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.4 10.7 GO:0007520 myoblast fusion(GO:0007520)
0.4 22.0 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.4 14.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.4 6.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.4 1.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4 2.5 GO:0009597 detection of virus(GO:0009597)
0.4 3.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.4 7.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 15.0 GO:0060996 dendritic spine development(GO:0060996)
0.3 3.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 4.4 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.3 1.7 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.3 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 5.9 GO:0003341 cilium movement(GO:0003341)
0.3 28.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 9.3 GO:0010107 potassium ion import(GO:0010107)
0.3 5.7 GO:0001975 response to amphetamine(GO:0001975)
0.3 18.4 GO:0045453 bone resorption(GO:0045453)
0.3 133.5 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.3 7.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 7.7 GO:0050919 negative chemotaxis(GO:0050919)
0.3 11.4 GO:0006986 response to unfolded protein(GO:0006986)
0.3 2.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 3.6 GO:0032526 response to retinoic acid(GO:0032526)
0.3 9.2 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.3 9.3 GO:0006284 base-excision repair(GO:0006284)
0.3 25.7 GO:0022900 electron transport chain(GO:0022900)
0.2 73.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.2 29.5 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.2 0.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.2 7.6 GO:0014047 glutamate secretion(GO:0014047)
0.2 6.3 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 17.7 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.2 11.1 GO:0046785 microtubule polymerization(GO:0046785)
0.2 1.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 14.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.2 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 3.4 GO:1901661 quinone metabolic process(GO:1901661)
0.2 2.0 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 9.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 5.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 6.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 22.0 GO:0007411 axon guidance(GO:0007411)
0.1 13.4 GO:0016579 protein deubiquitination(GO:0016579)
0.1 2.2 GO:0000910 cytokinesis(GO:0000910)
0.0 0.4 GO:0022029 cerebral cortex cell migration(GO:0021795) telencephalon cell migration(GO:0022029)
0.0 13.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.1 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.4 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 2.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.6 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 4.9 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 2.6 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 7.6 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 3.9 GO:0045860 positive regulation of protein kinase activity(GO:0045860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
30.7 122.7 GO:0097224 sperm connecting piece(GO:0097224)
29.0 116.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
19.9 19.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
14.7 59.0 GO:0016939 kinesin II complex(GO:0016939)
13.0 65.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
12.1 144.7 GO:0033010 paranodal junction(GO:0033010)
11.9 71.2 GO:0000138 Golgi trans cisterna(GO:0000138)
11.4 68.7 GO:0002177 manchette(GO:0002177)
11.4 34.1 GO:0044609 DBIRD complex(GO:0044609)
11.3 67.6 GO:1990769 proximal neuron projection(GO:1990769)
9.6 192.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
7.1 35.6 GO:0036128 CatSper complex(GO:0036128)
6.7 46.9 GO:0001520 outer dense fiber(GO:0001520)
6.3 75.9 GO:0060077 inhibitory synapse(GO:0060077)
5.9 52.8 GO:0034464 BBSome(GO:0034464)
5.7 39.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
5.5 77.2 GO:0036038 MKS complex(GO:0036038)
5.4 65.4 GO:0035869 ciliary transition zone(GO:0035869)
5.4 16.3 GO:0055028 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
4.9 83.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
4.4 21.9 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
4.2 33.4 GO:0044294 dendritic growth cone(GO:0044294)
4.0 19.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
3.9 65.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
3.9 54.0 GO:0035102 PRC1 complex(GO:0035102)
3.8 80.6 GO:0034451 centriolar satellite(GO:0034451)
3.8 72.7 GO:0097225 sperm midpiece(GO:0097225)
3.7 25.8 GO:0097427 microtubule bundle(GO:0097427)
3.3 177.8 GO:0016235 aggresome(GO:0016235)
3.2 31.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
3.1 21.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
3.1 33.6 GO:0097431 mitotic spindle pole(GO:0097431)
3.0 56.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.9 25.8 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
2.8 25.2 GO:0032797 SMN complex(GO:0032797)
2.7 10.9 GO:1990031 pinceau fiber(GO:1990031)
2.7 72.1 GO:0035371 microtubule plus-end(GO:0035371)
2.7 31.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
2.6 21.0 GO:0030992 intraciliary transport particle B(GO:0030992)
2.6 216.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
2.6 12.9 GO:0070847 core mediator complex(GO:0070847)
2.6 28.2 GO:0002116 semaphorin receptor complex(GO:0002116)
2.5 12.7 GO:0000137 Golgi cis cisterna(GO:0000137)
2.1 25.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.8 21.7 GO:0016342 catenin complex(GO:0016342)
1.5 10.8 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
1.5 90.8 GO:0036064 ciliary basal body(GO:0036064)
1.4 18.1 GO:0008091 spectrin(GO:0008091)
1.4 4.2 GO:0031251 PAN complex(GO:0031251)
1.4 15.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.3 13.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
1.3 10.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.2 13.6 GO:0035686 sperm fibrous sheath(GO:0035686)
1.2 24.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
1.1 97.7 GO:0001669 acrosomal vesicle(GO:0001669)
1.1 27.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.0 49.4 GO:0043034 costamere(GO:0043034)
1.0 24.2 GO:0097546 ciliary base(GO:0097546)
0.9 35.1 GO:1904115 axon cytoplasm(GO:1904115)
0.8 58.7 GO:0043195 terminal bouton(GO:0043195)
0.7 16.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.7 47.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.7 20.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.7 2.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.7 67.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.6 35.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.6 16.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.6 8.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.6 3.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5 45.2 GO:0032587 ruffle membrane(GO:0032587)
0.5 37.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 2.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 3.0 GO:0043196 varicosity(GO:0043196)
0.5 174.2 GO:0005874 microtubule(GO:0005874)
0.5 66.5 GO:0031901 early endosome membrane(GO:0031901)
0.5 23.4 GO:0005801 cis-Golgi network(GO:0005801)
0.5 24.1 GO:0005814 centriole(GO:0005814)
0.5 71.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.5 88.9 GO:0005802 trans-Golgi network(GO:0005802)
0.5 56.8 GO:0043204 perikaryon(GO:0043204)
0.4 3.1 GO:0097228 sperm principal piece(GO:0097228)
0.3 85.6 GO:0005938 cell cortex(GO:0005938)
0.3 20.8 GO:0005811 lipid particle(GO:0005811)
0.3 7.6 GO:0048786 presynaptic active zone(GO:0048786)
0.3 38.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 7.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 40.3 GO:0001650 fibrillar center(GO:0001650)
0.3 17.3 GO:0005776 autophagosome(GO:0005776)
0.3 4.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 24.1 GO:0030027 lamellipodium(GO:0030027)
0.3 27.8 GO:0008021 synaptic vesicle(GO:0008021)
0.3 3.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 26.7 GO:0005796 Golgi lumen(GO:0005796)
0.2 16.7 GO:0000922 spindle pole(GO:0000922)
0.2 18.3 GO:0031902 late endosome membrane(GO:0031902)
0.2 30.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 4.9 GO:0005921 gap junction(GO:0005921)
0.2 1.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 9.0 GO:0001726 ruffle(GO:0001726)
0.2 126.6 GO:0043005 neuron projection(GO:0043005)
0.2 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 22.4 GO:0030055 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.1 2.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 5.3 GO:0005903 brush border(GO:0005903)
0.1 1.4 GO:0005771 multivesicular body(GO:0005771)
0.1 7.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 6.2 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 3.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.1 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
29.0 116.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
13.7 82.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
13.4 40.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
10.2 122.7 GO:0032027 myosin light chain binding(GO:0032027)
9.8 29.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
9.6 38.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
9.5 28.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
9.1 27.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
9.1 72.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
8.8 26.4 GO:0015439 heme-transporting ATPase activity(GO:0015439)
8.4 50.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
7.7 30.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
6.1 24.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
6.1 30.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
6.1 139.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
5.8 17.3 GO:0015235 cobalamin transporter activity(GO:0015235)
5.6 33.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
5.3 47.9 GO:0032051 clathrin light chain binding(GO:0032051)
4.7 19.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
4.6 18.4 GO:0035473 lipase binding(GO:0035473)
4.4 242.2 GO:0017080 sodium channel regulator activity(GO:0017080)
4.3 86.3 GO:0045504 dynein heavy chain binding(GO:0045504)
4.3 12.9 GO:1904288 BAT3 complex binding(GO:1904288)
4.2 12.7 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
4.1 32.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
4.0 23.7 GO:0005119 smoothened binding(GO:0005119)
3.9 19.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
3.5 165.6 GO:0030507 spectrin binding(GO:0030507)
3.2 12.7 GO:0008158 hedgehog receptor activity(GO:0008158)
3.1 15.5 GO:0050815 phosphoserine binding(GO:0050815)
3.0 35.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
2.9 143.6 GO:0046875 ephrin receptor binding(GO:0046875)
2.9 8.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.8 8.5 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.8 22.6 GO:0034452 dynactin binding(GO:0034452)
2.8 22.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
2.8 13.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
2.5 27.6 GO:0004645 phosphorylase activity(GO:0004645)
2.5 92.0 GO:0030552 cAMP binding(GO:0030552)
2.3 11.6 GO:0070568 guanylyltransferase activity(GO:0070568)
2.3 62.3 GO:0008198 ferrous iron binding(GO:0008198)
2.3 96.9 GO:0003785 actin monomer binding(GO:0003785)
2.2 24.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.2 72.5 GO:0070840 dynein complex binding(GO:0070840)
2.2 25.8 GO:0048156 tau protein binding(GO:0048156)
2.1 35.4 GO:0003746 translation elongation factor activity(GO:0003746)
2.1 41.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
2.0 28.2 GO:0030215 semaphorin receptor binding(GO:0030215)
2.0 10.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.0 23.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
2.0 31.6 GO:0004526 ribonuclease P activity(GO:0004526)
1.8 10.9 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
1.6 16.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.6 90.0 GO:0043022 ribosome binding(GO:0043022)
1.5 33.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.5 78.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
1.5 20.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.4 35.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.4 21.7 GO:0008179 adenylate cyclase binding(GO:0008179)
1.3 35.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.3 34.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.3 23.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
1.3 82.2 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
1.3 21.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.2 13.6 GO:0043015 gamma-tubulin binding(GO:0043015)
1.2 21.5 GO:0017049 GTP-Rho binding(GO:0017049)
1.2 9.3 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.1 5.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.1 124.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.1 114.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
1.1 9.9 GO:0001222 transcription corepressor binding(GO:0001222)
1.1 117.0 GO:0008013 beta-catenin binding(GO:0008013)
1.1 3.2 GO:0070984 SET domain binding(GO:0070984)
1.1 16.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0 27.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
1.0 37.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.0 16.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.9 18.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.9 60.3 GO:0019843 rRNA binding(GO:0019843)
0.9 7.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.9 3.4 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.8 15.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8 22.1 GO:0071949 FAD binding(GO:0071949)
0.8 93.9 GO:0005496 steroid binding(GO:0005496)
0.8 7.7 GO:0038191 neuropilin binding(GO:0038191)
0.8 136.4 GO:0005178 integrin binding(GO:0005178)
0.7 64.7 GO:0030165 PDZ domain binding(GO:0030165)
0.7 188.1 GO:0008017 microtubule binding(GO:0008017)
0.7 13.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.7 66.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 19.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.7 20.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.7 6.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 3.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.6 25.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.6 44.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.5 9.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 17.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 6.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.5 2.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 2.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.5 13.6 GO:0051018 protein kinase A binding(GO:0051018)
0.5 1.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 6.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 59.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 7.0 GO:0008483 transaminase activity(GO:0008483)
0.4 61.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 10.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.3 2.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 4.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 0.9 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 40.3 GO:0017124 SH3 domain binding(GO:0017124)
0.3 90.5 GO:0003924 GTPase activity(GO:0003924)
0.3 3.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 6.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 3.4 GO:0016594 glycine binding(GO:0016594)
0.2 3.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 10.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 8.5 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 5.9 GO:0017091 AU-rich element binding(GO:0017091)
0.2 2.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 10.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 10.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 12.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 9.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 12.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 5.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 3.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 40.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.6 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 15.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1