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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for RHOXF1
Z-value: 0.67
Motif logo
Transcription factors associated with RHOXF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RHOXF1
|
ENSG00000101883.4 | Rhox homeobox family member 1 |
Activity profile of RHOXF1 motif
Sorted Z-values of RHOXF1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of RHOXF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.6 | 34.2 | GO:0010900 | negative regulation of phosphatidylcholine catabolic process(GO:0010900) |
| 6.6 | 26.2 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 5.9 | 35.2 | GO:1902847 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 4.8 | 58.1 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 4.6 | 13.7 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 4.1 | 24.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 3.9 | 7.9 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 3.8 | 15.3 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 3.6 | 10.7 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 3.4 | 10.2 | GO:0060621 | regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
| 3.2 | 12.9 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 3.1 | 15.6 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 3.1 | 9.3 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547) |
| 3.1 | 12.2 | GO:0003095 | pressure natriuresis(GO:0003095) |
| 3.0 | 8.9 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 2.8 | 11.0 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 2.7 | 35.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 2.7 | 16.1 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 2.6 | 12.9 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 2.5 | 10.0 | GO:0071231 | cellular response to folic acid(GO:0071231) |
| 2.5 | 7.4 | GO:0003218 | cardiac left ventricle formation(GO:0003218) |
| 2.5 | 19.7 | GO:0009635 | response to herbicide(GO:0009635) |
| 2.4 | 9.7 | GO:0015746 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 2.4 | 7.2 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 2.4 | 11.9 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 2.4 | 9.5 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 2.3 | 9.3 | GO:0048749 | compound eye development(GO:0048749) |
| 2.3 | 6.8 | GO:0090034 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 2.1 | 8.6 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 2.1 | 6.4 | GO:0030187 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 2.0 | 6.0 | GO:0003383 | apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509) |
| 1.9 | 7.8 | GO:0099525 | presynaptic dense core granule exocytosis(GO:0099525) |
| 1.9 | 5.8 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 1.9 | 5.7 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 1.9 | 3.8 | GO:0070861 | regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 1.8 | 5.4 | GO:0048867 | stem cell fate determination(GO:0048867) |
| 1.8 | 5.3 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
| 1.7 | 5.2 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 1.7 | 6.9 | GO:0010652 | regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) |
| 1.7 | 5.2 | GO:0045210 | negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) |
| 1.7 | 5.1 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.7 | 5.0 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 1.6 | 13.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 1.6 | 1.6 | GO:0016078 | tRNA catabolic process(GO:0016078) |
| 1.6 | 1.6 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 1.6 | 6.4 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288) |
| 1.6 | 1.6 | GO:0035625 | epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 1.6 | 11.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 1.5 | 7.7 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 1.5 | 4.6 | GO:2000439 | positive regulation of monocyte extravasation(GO:2000439) |
| 1.5 | 7.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 1.5 | 1.5 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) |
| 1.5 | 3.0 | GO:0031627 | telomeric loop formation(GO:0031627) |
| 1.5 | 13.5 | GO:0072143 | mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) |
| 1.5 | 7.3 | GO:0030070 | insulin processing(GO:0030070) |
| 1.4 | 4.2 | GO:0071373 | luteinizing hormone signaling pathway(GO:0042700) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 1.3 | 8.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 1.3 | 34.7 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 1.3 | 5.1 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 1.3 | 3.8 | GO:1904430 | negative regulation of t-circle formation(GO:1904430) |
| 1.3 | 7.7 | GO:0051012 | microtubule sliding(GO:0051012) |
| 1.3 | 5.1 | GO:0051352 | negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin-protein transferase activity(GO:0051444) regulation of ubiquitin protein ligase activity(GO:1904666) negative regulation of ubiquitin protein ligase activity(GO:1904667) positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 1.3 | 8.9 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 1.2 | 7.4 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666) |
| 1.2 | 7.3 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 1.2 | 4.8 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 1.2 | 10.8 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
| 1.2 | 21.6 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 1.2 | 6.0 | GO:0097267 | omega-hydroxylase P450 pathway(GO:0097267) |
| 1.2 | 4.8 | GO:0007418 | ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) |
| 1.2 | 2.4 | GO:0018343 | protein farnesylation(GO:0018343) |
| 1.2 | 28.3 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 1.2 | 5.9 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 1.2 | 4.7 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 1.2 | 5.8 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 1.2 | 3.5 | GO:0070781 | response to biotin(GO:0070781) |
| 1.2 | 16.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.2 | 1.2 | GO:2000538 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 1.1 | 4.5 | GO:0038066 | p38MAPK cascade(GO:0038066) regulation of p38MAPK cascade(GO:1900744) positive regulation of p38MAPK cascade(GO:1900745) |
| 1.1 | 5.6 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.1 | 13.4 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 1.1 | 8.9 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 1.1 | 4.4 | GO:0014734 | skeletal muscle hypertrophy(GO:0014734) |
| 1.1 | 4.4 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 1.1 | 4.3 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 1.1 | 4.3 | GO:0042126 | nitrate metabolic process(GO:0042126) |
| 1.1 | 3.2 | GO:0051710 | regulation of cytolysis in other organism(GO:0051710) |
| 1.1 | 9.6 | GO:0006069 | ethanol oxidation(GO:0006069) |
| 1.0 | 1.0 | GO:2000437 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 1.0 | 7.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.0 | 5.1 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 1.0 | 6.0 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 1.0 | 3.9 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 1.0 | 2.0 | GO:0060129 | thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
| 1.0 | 2.9 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 1.0 | 24.4 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 1.0 | 2.9 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 1.0 | 5.7 | GO:0071105 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
| 0.9 | 2.8 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.9 | 6.6 | GO:0048241 | epinephrine transport(GO:0048241) |
| 0.9 | 9.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.9 | 7.4 | GO:0030917 | midbrain-hindbrain boundary development(GO:0030917) |
| 0.9 | 2.8 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.9 | 3.7 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.9 | 3.6 | GO:0021997 | response to chlorate(GO:0010157) neural plate axis specification(GO:0021997) |
| 0.9 | 8.1 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.9 | 4.4 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.9 | 2.6 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.9 | 3.5 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.9 | 1.7 | GO:0070434 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434) |
| 0.9 | 2.6 | GO:0097254 | renal tubular secretion(GO:0097254) |
| 0.8 | 7.6 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.8 | 4.2 | GO:0010286 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 0.8 | 5.8 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.8 | 3.3 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.8 | 6.6 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.8 | 5.8 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.8 | 4.9 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.8 | 6.6 | GO:0015705 | iodide transport(GO:0015705) |
| 0.8 | 12.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.8 | 4.0 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) |
| 0.8 | 26.6 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.8 | 3.2 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.8 | 2.4 | GO:0001983 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 0.8 | 2.3 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.8 | 2.3 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.8 | 2.3 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.8 | 3.8 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.8 | 8.3 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.8 | 2.3 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
| 0.8 | 5.3 | GO:0045007 | depurination(GO:0045007) |
| 0.8 | 6.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.7 | 4.5 | GO:0016125 | sterol metabolic process(GO:0016125) |
| 0.7 | 3.7 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.7 | 0.7 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.7 | 4.4 | GO:0030578 | PML body organization(GO:0030578) |
| 0.7 | 11.7 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.7 | 17.5 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.7 | 1.4 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.7 | 2.2 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.7 | 10.0 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.7 | 5.6 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.7 | 30.8 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 0.7 | 2.1 | GO:0001840 | neural plate development(GO:0001840) |
| 0.7 | 2.8 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.7 | 2.8 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.7 | 5.5 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.7 | 1.3 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.7 | 1.3 | GO:0086021 | SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 0.7 | 14.0 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.7 | 2.0 | GO:1903401 | L-lysine transmembrane transport(GO:1903401) |
| 0.7 | 9.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.7 | 5.2 | GO:0046886 | positive regulation of hormone biosynthetic process(GO:0046886) |
| 0.7 | 2.6 | GO:2000320 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.6 | 3.8 | GO:0001714 | endodermal cell fate specification(GO:0001714) |
| 0.6 | 1.9 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 0.6 | 1.9 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.6 | 10.6 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 0.6 | 3.6 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.6 | 3.0 | GO:0045906 | regulation of vascular smooth muscle contraction(GO:0003056) negative regulation of vasoconstriction(GO:0045906) |
| 0.6 | 4.8 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.6 | 2.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.6 | 5.4 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.6 | 8.3 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.6 | 0.6 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
| 0.6 | 2.9 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.6 | 8.1 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.6 | 1.7 | GO:0050912 | detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.6 | 1.7 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.6 | 8.6 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.6 | 5.1 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.6 | 1.7 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.6 | 2.8 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.6 | 4.4 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.6 | 6.1 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
| 0.6 | 6.6 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.6 | 2.2 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 0.5 | 1.6 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.5 | 3.3 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.5 | 1.1 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 0.5 | 3.2 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.5 | 5.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.5 | 7.5 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.5 | 1.6 | GO:0086100 | endothelin receptor signaling pathway(GO:0086100) |
| 0.5 | 9.4 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 1.6 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.5 | 2.1 | GO:0042640 | anagen(GO:0042640) negative regulation of defense response to bacterium(GO:1900425) |
| 0.5 | 1.6 | GO:0009624 | response to nematode(GO:0009624) |
| 0.5 | 2.1 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.5 | 3.1 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.5 | 1.5 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.5 | 2.0 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.5 | 9.1 | GO:0034380 | high-density lipoprotein particle assembly(GO:0034380) |
| 0.5 | 2.0 | GO:0044026 | DNA hypermethylation(GO:0044026) |
| 0.5 | 6.8 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.5 | 7.7 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.5 | 4.8 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
| 0.5 | 7.1 | GO:1902221 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.5 | 1.9 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.5 | 4.2 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.5 | 2.3 | GO:0071873 | response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874) |
| 0.5 | 2.7 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.5 | 1.4 | GO:0042746 | regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746) |
| 0.5 | 1.8 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.4 | 1.3 | GO:0035963 | cellular response to interleukin-13(GO:0035963) |
| 0.4 | 1.8 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.4 | 8.8 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.4 | 2.6 | GO:0033504 | floor plate development(GO:0033504) |
| 0.4 | 2.2 | GO:0072233 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.4 | 1.7 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.4 | 4.7 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.4 | 2.6 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
| 0.4 | 2.1 | GO:1901098 | regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098) |
| 0.4 | 3.0 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.4 | 1.3 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
| 0.4 | 9.2 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 8.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.4 | 0.8 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643) |
| 0.4 | 3.3 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
| 0.4 | 0.8 | GO:0032430 | positive regulation of phospholipase A2 activity(GO:0032430) |
| 0.4 | 1.6 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.4 | 4.5 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.4 | 1.6 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 0.4 | 4.5 | GO:0050962 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.4 | 4.0 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.4 | 2.4 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 1.2 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.4 | 5.6 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.4 | 2.8 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
| 0.4 | 1.2 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.4 | 2.4 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.4 | 2.0 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.4 | 10.1 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.4 | 5.4 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.4 | 5.4 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.4 | 5.4 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.4 | 1.1 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.4 | 4.1 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.4 | 6.7 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.4 | 3.4 | GO:0070166 | enamel mineralization(GO:0070166) regulation of tooth mineralization(GO:0070170) |
| 0.4 | 4.5 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.4 | 4.8 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.4 | 2.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.4 | 1.8 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.4 | 6.2 | GO:0051197 | positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.4 | 0.7 | GO:0046618 | drug export(GO:0046618) |
| 0.4 | 1.1 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.4 | 0.7 | GO:0071314 | cellular response to cocaine(GO:0071314) |
| 0.4 | 3.6 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.4 | 2.5 | GO:0042048 | olfactory behavior(GO:0042048) |
| 0.4 | 2.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.4 | 1.8 | GO:0007320 | insemination(GO:0007320) |
| 0.4 | 41.1 | GO:0070268 | cornification(GO:0070268) |
| 0.4 | 1.1 | GO:1904481 | response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482) |
| 0.3 | 1.0 | GO:0002522 | leukocyte migration involved in immune response(GO:0002522) |
| 0.3 | 3.1 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.3 | 1.0 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.3 | 1.7 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) |
| 0.3 | 6.1 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.3 | 1.7 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 0.3 | 1.0 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.3 | 0.3 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.3 | 3.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.3 | 2.9 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.3 | 7.1 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.3 | 2.2 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.3 | 1.9 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.3 | 0.9 | GO:2000724 | nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724) |
| 0.3 | 5.7 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.3 | 5.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.3 | 1.6 | GO:0097461 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.3 | 0.6 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.3 | 0.9 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 0.3 | 8.9 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.3 | 2.7 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.3 | 2.7 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 3.6 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.3 | 3.9 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 0.3 | 5.1 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.3 | 0.9 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 0.3 | 15.0 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.3 | 2.4 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 6.7 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.3 | 3.5 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.3 | 1.5 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.3 | 2.0 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 1.4 | GO:0015747 | urate transport(GO:0015747) |
| 0.3 | 2.3 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.3 | 2.0 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.3 | 11.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 1.1 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.3 | 6.7 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.3 | 4.3 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.3 | 3.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.3 | 2.3 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.3 | 0.8 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.3 | 1.3 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.3 | 1.3 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.3 | 1.0 | GO:0060492 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
| 0.3 | 3.0 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.3 | 2.0 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.3 | 2.0 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.2 | 1.2 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.2 | 0.5 | GO:0050961 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.2 | 5.6 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.2 | 1.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 2.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.2 | 0.7 | GO:0014735 | regulation of muscle atrophy(GO:0014735) negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876) |
| 0.2 | 0.9 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.2 | 2.8 | GO:0071468 | cellular response to acidic pH(GO:0071468) |
| 0.2 | 4.5 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.2 | 14.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.2 | 2.6 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.2 | 11.4 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.2 | 4.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.2 | 1.8 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.2 | 1.3 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.2 | 1.3 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.2 | 3.5 | GO:0014902 | myotube differentiation(GO:0014902) |
| 0.2 | 12.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.2 | 1.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.2 | 2.6 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.2 | 32.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.2 | 1.1 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
| 0.2 | 4.3 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.2 | 1.7 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.2 | 15.8 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.2 | 3.4 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.2 | 2.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.2 | 1.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 0.8 | GO:0033574 | response to testosterone(GO:0033574) |
| 0.2 | 2.3 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.2 | 4.1 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.2 | 2.9 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.2 | 1.2 | GO:0048477 | oogenesis(GO:0048477) |
| 0.2 | 0.6 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.2 | 5.8 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 6.0 | GO:0072337 | modified amino acid transport(GO:0072337) |
| 0.2 | 0.8 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.2 | 1.6 | GO:1990776 | cellular response to angiotensin(GO:1904385) response to angiotensin(GO:1990776) |
| 0.2 | 4.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.2 | 23.2 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.2 | 5.2 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.2 | 4.2 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.2 | 1.3 | GO:0002775 | antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) |
| 0.2 | 1.1 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.2 | 1.1 | GO:0046015 | regulation of transcription by glucose(GO:0046015) |
| 0.2 | 2.4 | GO:0048265 | response to pain(GO:0048265) |
| 0.2 | 0.4 | GO:0003011 | diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011) |
| 0.2 | 1.3 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 3.5 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.2 | 2.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 1.7 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.2 | 1.2 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 0.7 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 4.3 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.2 | 1.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.2 | 7.4 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.2 | 2.7 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
| 0.2 | 6.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.2 | 1.6 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 0.5 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.2 | 0.9 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.2 | 1.6 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
| 0.2 | 2.8 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.2 | 0.6 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.2 | 0.8 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.2 | 0.5 | GO:0042701 | progesterone secretion(GO:0042701) regulation of progesterone secretion(GO:2000870) |
| 0.1 | 2.1 | GO:0002544 | chronic inflammatory response(GO:0002544) |
| 0.1 | 4.7 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.1 | 2.3 | GO:0032729 | positive regulation of interferon-gamma production(GO:0032729) |
| 0.1 | 0.9 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.1 | 4.2 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 1.0 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.1 | 2.2 | GO:0071027 | nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.1 | 0.4 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
| 0.1 | 0.8 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.1 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.1 | 2.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.1 | 4.6 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 12.4 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.1 | 1.5 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 1.5 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.1 | 0.7 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.1 | 6.7 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.1 | 1.4 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.1 | 6.3 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 0.1 | 1.3 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.1 | 0.5 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.1 | 1.4 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.2 | GO:0045448 | regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) |
| 0.1 | 0.7 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 0.8 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
| 0.1 | 2.2 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 2.6 | GO:0046676 | negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278) |
| 0.1 | 0.5 | GO:0038169 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.1 | 0.5 | GO:0043305 | negative regulation of mast cell degranulation(GO:0043305) |
| 0.1 | 6.9 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.1 | 5.0 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.1 | 0.9 | GO:0030815 | negative regulation of cAMP metabolic process(GO:0030815) |
| 0.1 | 0.7 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.1 | 1.6 | GO:0086091 | regulation of heart rate by cardiac conduction(GO:0086091) |
| 0.1 | 2.3 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.1 | 0.6 | GO:0060080 | inhibitory postsynaptic potential(GO:0060080) |
| 0.1 | 2.4 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.1 | 3.7 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 1.7 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.1 | 2.9 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.1 | 2.1 | GO:0009306 | protein secretion(GO:0009306) |
| 0.1 | 6.1 | GO:0007268 | chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537) |
| 0.1 | 4.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 6.5 | GO:0007586 | digestion(GO:0007586) |
| 0.1 | 2.0 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.1 | 7.6 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.1 | 0.5 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.1 | 1.7 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 1.4 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.1 | 0.9 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
| 0.1 | 1.9 | GO:0009880 | embryonic pattern specification(GO:0009880) |
| 0.1 | 2.3 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.1 | 1.5 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 0.8 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.1 | 1.9 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.1 | 1.3 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.1 | 1.3 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.1 | 1.0 | GO:0040019 | positive regulation of embryonic development(GO:0040019) |
| 0.1 | 0.3 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 3.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.1 | 1.8 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 2.5 | GO:0021510 | spinal cord development(GO:0021510) |
| 0.1 | 0.4 | GO:0072163 | ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164) |
| 0.1 | 5.3 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 1.2 | GO:0048246 | macrophage chemotaxis(GO:0048246) |
| 0.1 | 0.2 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 1.6 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 0.9 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 0.3 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.3 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
| 0.1 | 0.7 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.0 | 1.2 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 4.0 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 0.8 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 1.3 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 0.3 | GO:0034311 | sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311) |
| 0.0 | 1.2 | GO:0072678 | T cell migration(GO:0072678) |
| 0.0 | 1.1 | GO:0010039 | response to iron ion(GO:0010039) |
| 0.0 | 0.6 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 0.0 | 1.2 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 2.9 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.0 | 0.9 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.0 | 0.6 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.1 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) |
| 0.0 | 1.3 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 0.0 | 0.4 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.0 | 0.2 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.0 | 1.2 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 0.3 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.2 | GO:1905097 | regulation of guanyl-nucleotide exchange factor activity(GO:1905097) |
| 0.0 | 0.6 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.7 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.3 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.0 | 0.1 | GO:0016093 | polyprenol metabolic process(GO:0016093) |
| 0.0 | 0.8 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664) |
| 0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.6 | GO:0009953 | dorsal/ventral pattern formation(GO:0009953) |
| 0.0 | 0.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 0.1 | GO:0043585 | nose morphogenesis(GO:0043585) lung saccule development(GO:0060430) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
| 0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.5 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.0 | 0.4 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
| 0.0 | 0.8 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.8 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.0 | 0.9 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.1 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.1 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.0 | 0.3 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 1.1 | GO:0035308 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 0.1 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.0 | 0.1 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.0 | 0.2 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.0 | 0.0 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.0 | 0.1 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.0 | 0.6 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.0 | GO:0006833 | water transport(GO:0006833) fluid transport(GO:0042044) |
| 0.0 | 0.1 | GO:0038089 | positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089) positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.0 | 0.2 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.2 | GO:0010644 | cell communication by electrical coupling(GO:0010644) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.6 | 42.5 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 3.1 | 43.0 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 2.8 | 45.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 2.7 | 45.4 | GO:0042627 | chylomicron(GO:0042627) |
| 2.6 | 7.8 | GO:0044305 | calyx of Held(GO:0044305) |
| 1.9 | 7.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 1.8 | 7.3 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 1.8 | 5.3 | GO:0097489 | multivesicular body, internal vesicle lumen(GO:0097489) |
| 1.7 | 5.2 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 1.3 | 20.0 | GO:0030478 | actin cap(GO:0030478) |
| 1.2 | 4.8 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 1.1 | 12.9 | GO:0043203 | axon hillock(GO:0043203) |
| 0.9 | 23.9 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.8 | 9.9 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.8 | 4.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.8 | 12.7 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.8 | 2.4 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.8 | 2.3 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.7 | 13.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.7 | 4.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.7 | 8.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.7 | 4.9 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.7 | 2.8 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.7 | 2.0 | GO:0016935 | glycine-gated chloride channel complex(GO:0016935) |
| 0.7 | 7.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.6 | 2.4 | GO:0031430 | M band(GO:0031430) |
| 0.6 | 124.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.6 | 11.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.6 | 2.3 | GO:0031673 | H zone(GO:0031673) |
| 0.6 | 1.7 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.6 | 15.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.6 | 15.1 | GO:0043218 | compact myelin(GO:0043218) |
| 0.6 | 2.8 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.5 | 3.9 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.5 | 4.8 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.5 | 3.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.5 | 4.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.5 | 3.6 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.4 | 4.9 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.4 | 16.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.4 | 3.1 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.4 | 7.1 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.4 | 3.1 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 0.4 | 3.5 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.4 | 9.6 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.4 | 1.3 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.4 | 1.7 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.4 | 4.3 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.4 | 4.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.4 | 5.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.4 | 5.8 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.4 | 4.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.4 | 5.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.4 | 2.3 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.4 | 19.8 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.4 | 2.6 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.4 | 3.3 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.4 | 1.4 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.4 | 13.8 | GO:0097546 | ciliary base(GO:0097546) |
| 0.3 | 4.2 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.3 | 5.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.3 | 4.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.3 | 4.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.3 | 3.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.3 | 5.6 | GO:0032059 | bleb(GO:0032059) |
| 0.3 | 1.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.3 | 5.1 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.3 | 35.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.3 | 8.2 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.3 | 5.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.3 | 11.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.3 | 6.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.3 | 3.9 | GO:0097386 | glial cell projection(GO:0097386) |
| 0.3 | 2.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.3 | 4.4 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.3 | 3.5 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.3 | 12.2 | GO:0030286 | dynein complex(GO:0030286) |
| 0.3 | 2.6 | GO:0031672 | A band(GO:0031672) |
| 0.3 | 14.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 7.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.3 | 1.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 22.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.3 | 11.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.3 | 24.7 | GO:0005814 | centriole(GO:0005814) |
| 0.3 | 1.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.3 | 4.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.3 | 1.3 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.3 | 14.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.3 | 2.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 2.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443) |
| 0.2 | 2.2 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.2 | 2.6 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.2 | 2.0 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.2 | 1.3 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.2 | 6.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 0.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.2 | 3.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 4.3 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.2 | 0.6 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.2 | 44.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.2 | 16.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 4.3 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.2 | 3.0 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.2 | 25.7 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 1.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.2 | 0.7 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.2 | 1.6 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 0.2 | 2.4 | GO:0005671 | SAGA complex(GO:0000124) Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 0.8 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
| 0.2 | 4.2 | GO:0045095 | keratin filament(GO:0045095) |
| 0.2 | 3.2 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.2 | 0.9 | GO:0030315 | T-tubule(GO:0030315) |
| 0.2 | 2.0 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 17.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 1.4 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 2.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 1.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 13.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 21.9 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 8.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 12.8 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.1 | 2.8 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 2.6 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.1 | 7.4 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 0.6 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 0.4 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 1.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 1.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 1.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 2.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 2.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 1.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 12.4 | GO:0005875 | microtubule associated complex(GO:0005875) |
| 0.1 | 2.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 3.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 114.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 0.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 4.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 16.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 9.2 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 1.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 16.0 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 10.1 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 2.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 0.3 | GO:0055087 | Ski complex(GO:0055087) |
| 0.1 | 4.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 106.8 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 0.1 | 19.0 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 3.9 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 2.9 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.1 | 2.6 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.1 | 1.4 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.1 | 0.4 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.1 | 1.0 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 3.7 | GO:0098793 | presynapse(GO:0098793) |
| 0.1 | 2.1 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 1.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 0.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 4.0 | GO:0030016 | myofibril(GO:0030016) |
| 0.0 | 1.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 1.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.5 | GO:0031904 | endosome lumen(GO:0031904) |
| 0.0 | 0.7 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 0.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 1.8 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 0.3 | GO:0032040 | small-subunit processome(GO:0032040) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 11.5 | 34.4 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 5.7 | 34.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 5.6 | 44.4 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 4.1 | 24.3 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 3.7 | 11.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 3.7 | 18.3 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 3.6 | 10.7 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 3.4 | 13.7 | GO:0032810 | sterol response element binding(GO:0032810) |
| 3.2 | 12.9 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 3.1 | 12.2 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 3.0 | 9.0 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 3.0 | 15.0 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 3.0 | 8.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 2.6 | 18.2 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 2.5 | 10.0 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 2.5 | 7.4 | GO:0047150 | betaine-homocysteine S-methyltransferase activity(GO:0047150) |
| 2.4 | 7.3 | GO:0070052 | collagen V binding(GO:0070052) |
| 2.4 | 9.7 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 2.4 | 11.9 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 2.3 | 20.6 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 2.3 | 11.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 2.1 | 6.2 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 2.0 | 4.0 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 1.9 | 7.5 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 1.8 | 14.7 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.8 | 7.2 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 1.8 | 7.1 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 1.7 | 5.2 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 1.7 | 34.6 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 1.7 | 6.6 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 1.6 | 4.9 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.6 | 6.4 | GO:0004365 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 1.6 | 9.6 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 1.6 | 11.0 | GO:0031433 | telethonin binding(GO:0031433) |
| 1.6 | 6.3 | GO:0019862 | IgA binding(GO:0019862) |
| 1.5 | 4.4 | GO:0004663 | protein geranylgeranyltransferase activity(GO:0004661) Rab geranylgeranyltransferase activity(GO:0004663) |
| 1.5 | 16.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 1.5 | 5.9 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 1.5 | 4.4 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 1.4 | 8.3 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) |
| 1.3 | 4.0 | GO:0015389 | pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 1.3 | 6.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 1.3 | 5.2 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 1.3 | 3.9 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 1.3 | 5.1 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 1.2 | 6.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.2 | 2.4 | GO:0031716 | calcitonin receptor binding(GO:0031716) |
| 1.2 | 16.2 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 1.2 | 4.6 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 1.1 | 7.9 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 1.1 | 6.7 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 1.1 | 27.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 1.1 | 5.5 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 1.1 | 5.5 | GO:0002046 | opsin binding(GO:0002046) |
| 1.1 | 4.3 | GO:0008940 | nitrate reductase activity(GO:0008940) |
| 1.0 | 5.2 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 1.0 | 5.1 | GO:0004359 | glutaminase activity(GO:0004359) |
| 1.0 | 14.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 1.0 | 2.0 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 1.0 | 4.0 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 1.0 | 6.8 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.9 | 2.8 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.9 | 2.7 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.9 | 15.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.9 | 3.6 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.9 | 3.5 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.8 | 57.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.8 | 1.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.8 | 11.6 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.8 | 4.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.8 | 12.9 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.8 | 3.2 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.8 | 22.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.8 | 18.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.8 | 6.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.8 | 4.7 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.8 | 2.4 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 0.8 | 15.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.8 | 3.8 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.8 | 1.5 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.7 | 3.7 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.7 | 3.6 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.7 | 5.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.7 | 5.1 | GO:0016405 | CoA-ligase activity(GO:0016405) |
| 0.7 | 6.5 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.7 | 4.3 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.7 | 3.5 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.7 | 2.8 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.7 | 2.7 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.7 | 3.4 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.7 | 2.0 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.7 | 2.0 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.7 | 2.0 | GO:0015189 | L-lysine transmembrane transporter activity(GO:0015189) |
| 0.7 | 3.3 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.7 | 1.3 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.6 | 3.9 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.6 | 10.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.6 | 8.1 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.6 | 4.3 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.6 | 4.3 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.6 | 3.6 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.6 | 3.6 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.6 | 2.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.6 | 14.0 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.6 | 2.9 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.6 | 2.3 | GO:0017089 | glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001) |
| 0.6 | 7.4 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.6 | 5.0 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.6 | 1.7 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.5 | 2.7 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.5 | 3.2 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.5 | 1.6 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.5 | 11.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.5 | 4.6 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.5 | 6.1 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.5 | 4.5 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.5 | 2.9 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.5 | 2.9 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.5 | 1.4 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
| 0.5 | 1.4 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.5 | 10.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.5 | 7.6 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.5 | 1.9 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.5 | 5.7 | GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 0.5 | 8.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.5 | 11.5 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.5 | 7.3 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.5 | 1.8 | GO:0004963 | follicle-stimulating hormone receptor activity(GO:0004963) |
| 0.5 | 4.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.5 | 8.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.5 | 15.9 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.4 | 4.0 | GO:1901702 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.4 | 44.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.4 | 18.1 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.4 | 5.7 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.4 | 11.8 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.4 | 1.6 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.4 | 2.0 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.4 | 0.8 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.4 | 6.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.4 | 2.8 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.4 | 1.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.4 | 6.0 | GO:0072349 | modified amino acid transmembrane transporter activity(GO:0072349) |
| 0.4 | 2.8 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.4 | 9.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.4 | 19.7 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.4 | 2.7 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.4 | 3.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.4 | 2.6 | GO:0016713 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
| 0.4 | 0.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.3 | 2.7 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.3 | 1.4 | GO:0016499 | orexin receptor activity(GO:0016499) |
| 0.3 | 3.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.3 | 12.5 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.3 | 1.0 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.3 | 5.0 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 5.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.3 | 3.6 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.3 | 2.3 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294) |
| 0.3 | 5.2 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.3 | 5.2 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.3 | 1.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.3 | 4.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.3 | 2.6 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.3 | 3.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.3 | 1.3 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.3 | 0.9 | GO:0017082 | mineralocorticoid receptor activity(GO:0017082) |
| 0.3 | 1.2 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.3 | 2.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.3 | 0.9 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
| 0.3 | 18.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.3 | 3.3 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.3 | 2.4 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 6.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 1.2 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.3 | 1.2 | GO:0016160 | amylase activity(GO:0016160) |
| 0.3 | 8.0 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.3 | 3.2 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.3 | 10.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.3 | 2.0 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 1.7 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.3 | 2.0 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.3 | 1.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.3 | 1.4 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.3 | 4.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 12.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.3 | 0.8 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.3 | 0.8 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.3 | 9.3 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.3 | 1.3 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.3 | 2.6 | GO:0009374 | biotin binding(GO:0009374) |
| 0.3 | 0.8 | GO:0005497 | androgen binding(GO:0005497) |
| 0.3 | 1.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.2 | 1.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 3.2 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.2 | 6.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 2.0 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.2 | 1.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 12.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 42.5 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.2 | 8.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.2 | 4.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 2.0 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.2 | 0.7 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.2 | 0.9 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.2 | 4.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.2 | 1.3 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.2 | 0.7 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.2 | 2.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.2 | 2.0 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.2 | 1.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.2 | 2.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 1.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.2 | 1.1 | GO:0070905 | serine binding(GO:0070905) |
| 0.2 | 4.3 | GO:0042805 | actinin binding(GO:0042805) |
| 0.2 | 5.6 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 2.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.2 | 5.2 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 1.2 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.2 | 0.8 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.2 | 17.3 | GO:0005179 | hormone activity(GO:0005179) |
| 0.2 | 3.6 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.2 | 1.7 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.2 | 3.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.2 | 2.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 4.9 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.2 | 0.2 | GO:1903763 | gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.2 | 7.2 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.2 | 1.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.2 | 4.0 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.2 | 1.1 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.2 | 5.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 0.9 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.2 | 4.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 0.7 | GO:0003867 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.2 | 5.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.2 | 14.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.2 | 2.6 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.2 | 0.8 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.2 | 2.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.2 | 3.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 1.3 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.2 | 1.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 1.4 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.2 | 0.3 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.2 | 2.8 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 3.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 1.5 | GO:0022842 | leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842) |
| 0.1 | 4.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 2.3 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
| 0.1 | 3.1 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.1 | 4.0 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 1.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 2.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 13.1 | GO:0005506 | iron ion binding(GO:0005506) |
| 0.1 | 1.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 0.7 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.5 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.1 | 0.6 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.1 | 1.7 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.1 | 3.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 2.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 6.6 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 2.0 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 2.4 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 2.2 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 2.0 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 0.5 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 1.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 3.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 2.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.1 | 3.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 2.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 3.3 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.1 | 0.7 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 0.4 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 0.1 | 0.6 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.1 | 12.3 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.1 | 0.5 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 3.3 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.6 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 1.6 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.8 | GO:0047498 | bile acid binding(GO:0032052) calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 1.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 2.3 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.7 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.1 | 7.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.5 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.1 | 1.5 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.1 | 0.7 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.1 | 1.3 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.1 | 7.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 5.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 1.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.6 | GO:0010181 | FMN binding(GO:0010181) |
| 0.1 | 2.9 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.1 | 1.1 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.1 | 3.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 2.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 1.3 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.1 | 1.6 | GO:0005126 | cytokine receptor binding(GO:0005126) |
| 0.1 | 2.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 2.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 0.3 | GO:0009008 | DNA-methyltransferase activity(GO:0009008) |
| 0.1 | 0.9 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 0.1 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.4 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.0 | 1.5 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 2.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 3.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.4 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.0 | 0.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.3 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.1 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.0 | 3.5 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 1.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 6.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 2.4 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 1.7 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 2.9 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.7 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 5.7 | GO:0016746 | transferase activity, transferring acyl groups(GO:0016746) |
| 0.0 | 2.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 0.4 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 2.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.1 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
| 0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 1.5 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.0 | 0.6 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.9 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.7 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.6 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.4 | GO:0015923 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.0 | 0.2 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 3.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 0.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 0.8 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.8 | GO:0017069 | snRNA binding(GO:0017069) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 52.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.6 | 6.7 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.6 | 5.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.6 | 150.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.6 | 1.7 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.5 | 2.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.5 | 11.1 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.4 | 5.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.4 | 1.6 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.4 | 14.6 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.4 | 18.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.4 | 16.2 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.3 | 4.5 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.3 | 2.7 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.3 | 4.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.3 | 18.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.3 | 5.1 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.3 | 4.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.3 | 16.2 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.3 | 1.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.3 | 13.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.3 | 59.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 5.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.3 | 16.3 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 11.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.2 | 2.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 8.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 6.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.2 | 1.6 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.2 | 2.8 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.2 | 4.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 10.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.2 | 1.3 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.2 | 13.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.2 | 6.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.2 | 6.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.2 | 17.9 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.5 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 4.6 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 7.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 2.1 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 1.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 2.0 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 0.5 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 2.0 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 6.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 1.0 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 6.5 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 26.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 5.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 1.7 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 10.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.1 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.1 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 1.0 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.5 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 42.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 2.1 | 57.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 1.2 | 9.6 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 1.1 | 24.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.0 | 15.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.9 | 1.7 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.9 | 1.7 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.8 | 23.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.8 | 11.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.7 | 13.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.7 | 39.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.7 | 6.6 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.7 | 5.9 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.6 | 17.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.6 | 7.0 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.6 | 15.1 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.6 | 11.0 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.6 | 10.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.5 | 20.8 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.5 | 7.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.5 | 21.7 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.5 | 10.8 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.5 | 18.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.4 | 28.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.4 | 4.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.4 | 5.1 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.4 | 11.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.4 | 14.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.4 | 6.7 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.4 | 5.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.4 | 19.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.4 | 1.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.4 | 10.1 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.4 | 11.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.4 | 4.8 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.4 | 8.8 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.3 | 6.1 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.3 | 1.7 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.3 | 4.4 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.3 | 2.8 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.3 | 0.6 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.3 | 3.1 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.3 | 7.4 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.3 | 8.9 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.3 | 12.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.3 | 3.3 | REACTOME OPSINS | Genes involved in Opsins |
| 0.3 | 10.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.3 | 9.8 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 13.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.3 | 8.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.3 | 14.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.3 | 1.0 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.3 | 13.0 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.3 | 5.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 8.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.2 | 1.6 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 14.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 10.5 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 4.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 34.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.2 | 7.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 4.8 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.2 | 1.5 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.2 | 1.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 17.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.2 | 2.7 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.2 | 3.0 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 2.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.2 | 2.8 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.2 | 3.3 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.2 | 22.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 3.9 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 2.6 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 2.0 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.2 | 11.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 7.3 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.2 | 2.6 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 1.7 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.2 | 2.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 2.4 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 2.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 7.1 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 2.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 5.1 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.1 | 3.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.1 | 1.2 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 6.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.9 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 1.8 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 3.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 5.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 4.7 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 0.1 | 1.1 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 1.2 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.0 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 20.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 4.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 5.9 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.8 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 3.9 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 6.4 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.7 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 3.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 1.1 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.1 | 8.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 1.2 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 1.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 1.0 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 1.3 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.1 | 2.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 0.8 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 1.6 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 0.9 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 1.3 | REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | Genes involved in Cytokine Signaling in Immune system |
| 0.1 | 2.4 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.6 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 4.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.6 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 1.4 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.6 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 2.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.2 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |