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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for RUNX1_RUNX2
Z-value: 1.08
Motif logo
Transcription factors associated with RUNX1_RUNX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RUNX1
|
ENSG00000159216.14 | RUNX family transcription factor 1 |
|
RUNX2
|
ENSG00000124813.16 | RUNX family transcription factor 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RUNX1 | hg19_v2_chr21_-_36260980_36261011 | 0.41 | 3.9e-10 | Click! |
| RUNX2 | hg19_v2_chr6_+_45389893_45389914, hg19_v2_chr6_+_45296391_45296464 | 0.38 | 4.3e-09 | Click! |
Activity profile of RUNX1_RUNX2 motif
Sorted Z-values of RUNX1_RUNX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_29641084 | 64.51 |
ENST00000544462.1
|
EVI2B
|
ecotropic viral integration site 2B |
| chr16_+_85942594 | 62.65 |
ENST00000566369.1
|
IRF8
|
interferon regulatory factor 8 |
| chr17_-_29641104 | 59.20 |
ENST00000577894.1
ENST00000330927.4 |
EVI2B
|
ecotropic viral integration site 2B |
| chr2_+_90077680 | 51.11 |
ENST00000390270.2
|
IGKV3D-20
|
immunoglobulin kappa variable 3D-20 |
| chr22_+_23241661 | 50.88 |
ENST00000390322.2
|
IGLJ2
|
immunoglobulin lambda joining 2 |
| chrX_-_106960285 | 45.26 |
ENST00000503515.1
ENST00000372397.2 |
TSC22D3
|
TSC22 domain family, member 3 |
| chr8_-_134072593 | 44.33 |
ENST00000427060.2
|
SLA
|
Src-like-adaptor |
| chr2_-_89442621 | 43.33 |
ENST00000492167.1
|
IGKV3-20
|
immunoglobulin kappa variable 3-20 |
| chr1_+_198608146 | 43.21 |
ENST00000367376.2
ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2 |
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr11_-_58345569 | 34.84 |
ENST00000528954.1
ENST00000528489.1 |
LPXN
|
leupaxin |
| chr4_-_84035868 | 33.23 |
ENST00000426923.2
ENST00000509973.1 |
PLAC8
|
placenta-specific 8 |
| chr4_-_84035905 | 32.90 |
ENST00000311507.4
|
PLAC8
|
placenta-specific 8 |
| chr1_+_209929377 | 32.63 |
ENST00000400959.3
ENST00000367025.3 |
TRAF3IP3
|
TRAF3 interacting protein 3 |
| chr16_+_23847339 | 32.05 |
ENST00000303531.7
|
PRKCB
|
protein kinase C, beta |
| chr22_+_23247030 | 29.89 |
ENST00000390324.2
|
IGLJ3
|
immunoglobulin lambda joining 3 |
| chr11_+_121447469 | 29.69 |
ENST00000532694.1
ENST00000534286.1 |
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing |
| chr16_+_23847267 | 29.29 |
ENST00000321728.7
|
PRKCB
|
protein kinase C, beta |
| chr12_-_53594227 | 28.42 |
ENST00000550743.2
|
ITGB7
|
integrin, beta 7 |
| chr1_+_209929494 | 28.17 |
ENST00000367026.3
|
TRAF3IP3
|
TRAF3 interacting protein 3 |
| chr14_+_100531615 | 27.20 |
ENST00000392920.3
|
EVL
|
Enah/Vasp-like |
| chr16_+_56965960 | 27.14 |
ENST00000439977.2
ENST00000344114.4 ENST00000300302.5 ENST00000379792.2 |
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| chr6_-_33048483 | 27.01 |
ENST00000419277.1
|
HLA-DPA1
|
major histocompatibility complex, class II, DP alpha 1 |
| chr16_+_30194916 | 26.67 |
ENST00000570045.1
ENST00000565497.1 ENST00000570244.1 |
CORO1A
|
coronin, actin binding protein, 1A |
| chr8_+_27168988 | 26.50 |
ENST00000397501.1
ENST00000338238.4 ENST00000544172.1 |
PTK2B
|
protein tyrosine kinase 2 beta |
| chr5_-_39219705 | 26.32 |
ENST00000351578.6
|
FYB
|
FYN binding protein |
| chr4_-_57524061 | 25.68 |
ENST00000508121.1
|
HOPX
|
HOP homeobox |
| chr14_-_106092403 | 25.13 |
ENST00000390543.2
|
IGHG4
|
immunoglobulin heavy constant gamma 4 (G4m marker) |
| chr11_+_1874200 | 24.69 |
ENST00000311604.3
|
LSP1
|
lymphocyte-specific protein 1 |
| chr5_-_39203093 | 24.55 |
ENST00000515010.1
|
FYB
|
FYN binding protein |
| chr16_+_226658 | 23.70 |
ENST00000320868.5
ENST00000397797.1 |
HBA1
|
hemoglobin, alpha 1 |
| chr1_-_25291475 | 23.35 |
ENST00000338888.3
ENST00000399916.1 |
RUNX3
|
runt-related transcription factor 3 |
| chr17_-_34417479 | 22.10 |
ENST00000225245.5
|
CCL3
|
chemokine (C-C motif) ligand 3 |
| chr5_-_39219641 | 21.74 |
ENST00000509072.1
ENST00000504542.1 ENST00000505428.1 ENST00000506557.1 |
FYB
|
FYN binding protein |
| chr2_-_158300556 | 21.57 |
ENST00000264192.3
|
CYTIP
|
cytohesin 1 interacting protein |
| chr19_-_36399149 | 21.52 |
ENST00000585901.2
ENST00000544690.2 ENST00000424586.3 ENST00000262629.4 ENST00000589517.1 |
TYROBP
|
TYRO protein tyrosine kinase binding protein |
| chr17_-_34625719 | 21.51 |
ENST00000422211.2
ENST00000542124.1 |
CCL3L1
|
chemokine (C-C motif) ligand 3-like 1 |
| chr12_-_112819896 | 21.50 |
ENST00000377560.5
ENST00000430131.2 ENST00000550722.1 ENST00000550724.1 |
HECTD4
|
HECT domain containing E3 ubiquitin protein ligase 4 |
| chr14_-_60097524 | 21.29 |
ENST00000342503.4
|
RTN1
|
reticulon 1 |
| chr6_+_31949801 | 21.17 |
ENST00000428956.2
ENST00000498271.1 |
C4A
|
complement component 4A (Rodgers blood group) |
| chr6_+_31982539 | 20.91 |
ENST00000435363.2
ENST00000425700.2 |
C4B
|
complement component 4B (Chido blood group) |
| chr6_+_32407619 | 20.80 |
ENST00000395388.2
ENST00000374982.5 |
HLA-DRA
|
major histocompatibility complex, class II, DR alpha |
| chr11_-_116968987 | 20.68 |
ENST00000434315.2
ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2 |
SIK3
|
SIK family kinase 3 |
| chr13_+_50070491 | 20.67 |
ENST00000496612.1
ENST00000357596.3 ENST00000485919.1 ENST00000442195.1 |
PHF11
|
PHD finger protein 11 |
| chr1_+_22964073 | 20.57 |
ENST00000402322.1
|
C1QA
|
complement component 1, q subcomponent, A chain |
| chr8_-_102803163 | 20.45 |
ENST00000523645.1
ENST00000520346.1 ENST00000220931.6 ENST00000522448.1 ENST00000522951.1 ENST00000522252.1 ENST00000519098.1 |
NCALD
|
neurocalcin delta |
| chr17_-_62009621 | 20.39 |
ENST00000349817.2
ENST00000392795.3 |
CD79B
|
CD79b molecule, immunoglobulin-associated beta |
| chr16_-_68033356 | 20.11 |
ENST00000393847.1
ENST00000573808.1 ENST00000572624.1 |
DPEP2
|
dipeptidase 2 |
| chr13_-_46756351 | 20.09 |
ENST00000323076.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr16_+_31366455 | 19.95 |
ENST00000268296.4
|
ITGAX
|
integrin, alpha X (complement component 3 receptor 4 subunit) |
| chr19_+_1067492 | 19.92 |
ENST00000586866.1
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr11_+_62475130 | 19.85 |
ENST00000294117.5
|
GNG3
|
guanine nucleotide binding protein (G protein), gamma 3 |
| chr12_-_54121212 | 19.18 |
ENST00000548263.1
ENST00000430117.2 ENST00000550804.1 ENST00000549173.1 ENST00000551900.1 ENST00000546619.1 ENST00000548177.1 ENST00000549349.1 |
CALCOCO1
|
calcium binding and coiled-coil domain 1 |
| chr17_-_34524157 | 19.04 |
ENST00000378354.4
ENST00000394484.1 |
CCL3L3
|
chemokine (C-C motif) ligand 3-like 3 |
| chr14_-_25103472 | 18.73 |
ENST00000216341.4
ENST00000382542.1 ENST00000382540.1 |
GZMB
|
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| chr11_+_67033881 | 18.72 |
ENST00000308595.5
ENST00000526285.1 |
ADRBK1
|
adrenergic, beta, receptor kinase 1 |
| chr12_-_54121261 | 18.65 |
ENST00000549784.1
ENST00000262059.4 |
CALCOCO1
|
calcium binding and coiled-coil domain 1 |
| chr11_+_60739115 | 18.23 |
ENST00000344028.5
ENST00000346437.4 |
CD6
|
CD6 molecule |
| chr21_-_46348694 | 17.89 |
ENST00000355153.4
ENST00000397850.2 |
ITGB2
|
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| chr12_+_25205446 | 17.69 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr12_+_25205568 | 17.46 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr19_-_15087839 | 17.39 |
ENST00000600144.1
|
SLC1A6
|
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| chr5_-_108745689 | 17.37 |
ENST00000361189.2
|
PJA2
|
praja ring finger 2, E3 ubiquitin protein ligase |
| chr17_-_62009702 | 17.17 |
ENST00000006750.3
|
CD79B
|
CD79b molecule, immunoglobulin-associated beta |
| chrX_+_48542168 | 17.09 |
ENST00000376701.4
|
WAS
|
Wiskott-Aldrich syndrome |
| chr6_+_32709119 | 17.04 |
ENST00000374940.3
|
HLA-DQA2
|
major histocompatibility complex, class II, DQ alpha 2 |
| chr1_+_161185032 | 16.94 |
ENST00000367992.3
ENST00000289902.1 |
FCER1G
|
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| chr19_-_51875894 | 16.83 |
ENST00000600427.1
ENST00000595217.1 ENST00000221978.5 |
NKG7
|
natural killer cell group 7 sequence |
| chr2_+_68592305 | 16.79 |
ENST00000234313.7
|
PLEK
|
pleckstrin |
| chr14_-_25103388 | 16.70 |
ENST00000526004.1
ENST00000415355.3 |
GZMB
|
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| chr17_-_10017864 | 16.68 |
ENST00000323816.4
|
GAS7
|
growth arrest-specific 7 |
| chr2_-_90538397 | 16.66 |
ENST00000443397.3
|
RP11-685N3.1
|
Uncharacterized protein |
| chr11_+_108093559 | 16.65 |
ENST00000278616.4
|
ATM
|
ataxia telangiectasia mutated |
| chr18_-_74701962 | 16.64 |
ENST00000585201.1
|
MBP
|
myelin basic protein |
| chr11_+_60739140 | 16.62 |
ENST00000313421.7
|
CD6
|
CD6 molecule |
| chr1_-_168513229 | 16.59 |
ENST00000367819.2
|
XCL2
|
chemokine (C motif) ligand 2 |
| chr6_-_32920794 | 16.54 |
ENST00000395305.3
ENST00000395303.3 ENST00000374843.4 ENST00000429234.1 |
HLA-DMA
XXbac-BPG181M17.5
|
major histocompatibility complex, class II, DM alpha Uncharacterized protein |
| chr2_+_87565634 | 16.46 |
ENST00000421835.2
|
IGKV3OR2-268
|
immunoglobulin kappa variable 3/OR2-268 (non-functional) |
| chr5_-_138725560 | 16.04 |
ENST00000412103.2
ENST00000457570.2 |
MZB1
|
marginal zone B and B1 cell-specific protein |
| chr16_+_2802623 | 16.02 |
ENST00000576924.1
ENST00000575009.1 ENST00000576415.1 ENST00000571378.1 |
SRRM2
|
serine/arginine repetitive matrix 2 |
| chr5_-_138725594 | 15.87 |
ENST00000302125.8
|
MZB1
|
marginal zone B and B1 cell-specific protein |
| chr14_-_21493884 | 15.86 |
ENST00000556974.1
ENST00000554419.1 ENST00000298687.5 ENST00000397858.1 ENST00000360463.3 ENST00000350792.3 ENST00000397847.2 |
NDRG2
|
NDRG family member 2 |
| chr22_+_22707260 | 15.45 |
ENST00000390293.1
|
IGLV5-48
|
immunoglobulin lambda variable 5-48 (non-functional) |
| chr9_+_115913222 | 15.44 |
ENST00000259392.3
|
SLC31A2
|
solute carrier family 31 (copper transporter), member 2 |
| chr11_-_64885111 | 15.35 |
ENST00000528598.1
ENST00000310597.4 |
ZNHIT2
|
zinc finger, HIT-type containing 2 |
| chr12_+_7055631 | 15.11 |
ENST00000543115.1
ENST00000399448.1 |
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr19_-_36233332 | 14.86 |
ENST00000592537.1
ENST00000246532.1 ENST00000344990.3 ENST00000588992.1 |
IGFLR1
|
IGF-like family receptor 1 |
| chr1_+_111415757 | 14.75 |
ENST00000429072.2
ENST00000271324.5 |
CD53
|
CD53 molecule |
| chr9_-_34710066 | 14.64 |
ENST00000378792.1
ENST00000259607.2 |
CCL21
|
chemokine (C-C motif) ligand 21 |
| chr3_+_45067659 | 14.34 |
ENST00000296130.4
|
CLEC3B
|
C-type lectin domain family 3, member B |
| chr10_+_70847852 | 14.19 |
ENST00000242465.3
|
SRGN
|
serglycin |
| chr5_-_149492904 | 14.14 |
ENST00000286301.3
ENST00000511344.1 |
CSF1R
|
colony stimulating factor 1 receptor |
| chr2_+_103035102 | 14.08 |
ENST00000264260.2
|
IL18RAP
|
interleukin 18 receptor accessory protein |
| chr11_+_121322832 | 13.93 |
ENST00000260197.7
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing |
| chr17_-_62084241 | 13.85 |
ENST00000449662.2
|
ICAM2
|
intercellular adhesion molecule 2 |
| chr11_+_1889880 | 13.79 |
ENST00000405957.2
|
LSP1
|
lymphocyte-specific protein 1 |
| chrX_-_70331298 | 13.72 |
ENST00000456850.2
ENST00000473378.1 ENST00000487883.1 ENST00000374202.2 |
IL2RG
|
interleukin 2 receptor, gamma |
| chrY_+_2709906 | 13.71 |
ENST00000430575.1
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1 |
| chr6_+_42847649 | 13.69 |
ENST00000424341.2
ENST00000602561.1 |
RPL7L1
|
ribosomal protein L7-like 1 |
| chr6_+_31582961 | 13.67 |
ENST00000376059.3
ENST00000337917.7 |
AIF1
|
allograft inflammatory factor 1 |
| chr3_+_50284321 | 13.65 |
ENST00000451956.1
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| chr14_-_21493649 | 13.63 |
ENST00000553442.1
ENST00000555869.1 ENST00000556457.1 ENST00000397844.2 ENST00000554415.1 |
NDRG2
|
NDRG family member 2 |
| chr12_-_8218997 | 13.61 |
ENST00000307637.4
|
C3AR1
|
complement component 3a receptor 1 |
| chr6_-_31514516 | 13.60 |
ENST00000303892.5
ENST00000483251.1 |
ATP6V1G2
|
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| chr3_-_18466026 | 13.58 |
ENST00000417717.2
|
SATB1
|
SATB homeobox 1 |
| chr17_+_25958174 | 13.56 |
ENST00000313648.6
ENST00000577392.1 ENST00000584661.1 ENST00000413914.2 |
LGALS9
|
lectin, galactoside-binding, soluble, 9 |
| chr22_+_23264766 | 13.39 |
ENST00000390331.2
|
IGLC7
|
immunoglobulin lambda constant 7 |
| chr2_+_68961934 | 13.28 |
ENST00000409202.3
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr6_+_292051 | 13.21 |
ENST00000344450.5
|
DUSP22
|
dual specificity phosphatase 22 |
| chr2_-_89278535 | 13.18 |
ENST00000390247.2
|
IGKV3-7
|
immunoglobulin kappa variable 3-7 (non-functional) |
| chr1_-_184006829 | 13.15 |
ENST00000361927.4
|
COLGALT2
|
collagen beta(1-O)galactosyltransferase 2 |
| chr17_+_7239821 | 13.10 |
ENST00000158762.3
ENST00000570457.2 |
ACAP1
|
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| chr5_+_156696362 | 13.09 |
ENST00000377576.3
|
CYFIP2
|
cytoplasmic FMR1 interacting protein 2 |
| chr8_-_19540086 | 12.90 |
ENST00000332246.6
|
CSGALNACT1
|
chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| chr2_-_89327228 | 12.82 |
ENST00000483158.1
|
IGKV3-11
|
immunoglobulin kappa variable 3-11 |
| chr2_+_68961905 | 12.81 |
ENST00000295381.3
|
ARHGAP25
|
Rho GTPase activating protein 25 |
| chr5_+_35856951 | 12.67 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chrX_+_37639264 | 12.64 |
ENST00000378588.4
|
CYBB
|
cytochrome b-245, beta polypeptide |
| chr1_+_158801095 | 12.59 |
ENST00000368141.4
|
MNDA
|
myeloid cell nuclear differentiation antigen |
| chr7_-_37024665 | 12.58 |
ENST00000396040.2
|
ELMO1
|
engulfment and cell motility 1 |
| chr18_+_32558208 | 12.53 |
ENST00000436190.2
|
MAPRE2
|
microtubule-associated protein, RP/EB family, member 2 |
| chr6_+_31553978 | 12.51 |
ENST00000376096.1
ENST00000376099.1 ENST00000376110.3 |
LST1
|
leukocyte specific transcript 1 |
| chr6_+_31553901 | 12.49 |
ENST00000418507.2
ENST00000438075.2 ENST00000376100.3 ENST00000376111.4 |
LST1
|
leukocyte specific transcript 1 |
| chr5_-_42811986 | 12.38 |
ENST00000511224.1
ENST00000507920.1 ENST00000510965.1 |
SEPP1
|
selenoprotein P, plasma, 1 |
| chr22_-_50524298 | 12.30 |
ENST00000311597.5
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr3_+_40518599 | 12.22 |
ENST00000314686.5
ENST00000447116.2 ENST00000429348.2 ENST00000456778.1 |
ZNF619
|
zinc finger protein 619 |
| chr1_-_150980828 | 12.21 |
ENST00000361936.5
ENST00000361738.6 |
FAM63A
|
family with sequence similarity 63, member A |
| chr4_-_71532339 | 12.17 |
ENST00000254801.4
|
IGJ
|
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides |
| chr17_-_1532106 | 12.09 |
ENST00000301335.5
ENST00000382147.4 |
SLC43A2
|
solute carrier family 43 (amino acid system L transporter), member 2 |
| chr6_-_137540477 | 12.06 |
ENST00000367735.2
ENST00000367739.4 ENST00000458076.1 ENST00000414770.1 |
IFNGR1
|
interferon gamma receptor 1 |
| chr2_+_90211643 | 11.92 |
ENST00000390277.2
|
IGKV3D-11
|
immunoglobulin kappa variable 3D-11 |
| chr19_+_1067144 | 11.87 |
ENST00000313093.2
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr22_-_19512893 | 11.78 |
ENST00000403084.1
ENST00000413119.2 |
CLDN5
|
claudin 5 |
| chr14_-_94854926 | 11.76 |
ENST00000402629.1
ENST00000556091.1 ENST00000554720.1 |
SERPINA1
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| chr16_+_1578674 | 11.55 |
ENST00000253934.5
|
TMEM204
|
transmembrane protein 204 |
| chr19_-_6720686 | 11.51 |
ENST00000245907.6
|
C3
|
complement component 3 |
| chr8_-_21771214 | 11.48 |
ENST00000276420.4
|
DOK2
|
docking protein 2, 56kDa |
| chr5_-_42812143 | 11.39 |
ENST00000514985.1
|
SEPP1
|
selenoprotein P, plasma, 1 |
| chr19_-_52255107 | 11.33 |
ENST00000595042.1
ENST00000304748.4 |
FPR1
|
formyl peptide receptor 1 |
| chr12_-_109025849 | 11.22 |
ENST00000228463.6
|
SELPLG
|
selectin P ligand |
| chr19_+_47813110 | 11.13 |
ENST00000355085.3
|
C5AR1
|
complement component 5a receptor 1 |
| chr12_-_10542617 | 11.02 |
ENST00000240618.6
|
KLRK1
|
killer cell lectin-like receptor subfamily K, member 1 |
| chr1_+_192544857 | 11.00 |
ENST00000367459.3
ENST00000469578.2 |
RGS1
|
regulator of G-protein signaling 1 |
| chr22_-_50523760 | 10.99 |
ENST00000395876.2
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr14_-_25078864 | 10.98 |
ENST00000216338.4
ENST00000557220.2 ENST00000382548.4 |
GZMH
|
granzyme H (cathepsin G-like 2, protein h-CCPX) |
| chr1_-_153517473 | 10.95 |
ENST00000368715.1
|
S100A4
|
S100 calcium binding protein A4 |
| chr19_+_41882598 | 10.88 |
ENST00000447302.2
ENST00000544232.1 ENST00000542945.1 ENST00000540732.1 |
TMEM91
CTC-435M10.3
|
transmembrane protein 91 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein |
| chr3_-_39322728 | 10.84 |
ENST00000541347.1
ENST00000412814.1 |
CX3CR1
|
chemokine (C-X3-C motif) receptor 1 |
| chr1_-_153348067 | 10.83 |
ENST00000368737.3
|
S100A12
|
S100 calcium binding protein A12 |
| chr5_+_75699149 | 10.75 |
ENST00000379730.3
|
IQGAP2
|
IQ motif containing GTPase activating protein 2 |
| chr17_+_19281034 | 10.73 |
ENST00000308406.5
ENST00000299612.7 |
MAPK7
|
mitogen-activated protein kinase 7 |
| chr6_+_28109703 | 10.55 |
ENST00000457389.2
ENST00000330236.6 |
ZKSCAN8
|
zinc finger with KRAB and SCAN domains 8 |
| chr5_-_137071756 | 10.54 |
ENST00000394937.3
ENST00000309755.4 |
KLHL3
|
kelch-like family member 3 |
| chr7_-_100844193 | 10.52 |
ENST00000440203.2
ENST00000379423.3 ENST00000223114.4 |
MOGAT3
|
monoacylglycerol O-acyltransferase 3 |
| chr15_+_84116106 | 10.49 |
ENST00000535412.1
ENST00000324537.5 |
SH3GL3
|
SH3-domain GRB2-like 3 |
| chr2_+_90153696 | 10.40 |
ENST00000417279.2
|
IGKV3D-15
|
immunoglobulin kappa variable 3D-15 (gene/pseudogene) |
| chr12_-_9760482 | 10.40 |
ENST00000229402.3
|
KLRB1
|
killer cell lectin-like receptor subfamily B, member 1 |
| chr17_-_37308824 | 10.40 |
ENST00000415163.1
ENST00000441877.1 ENST00000444911.2 |
PLXDC1
|
plexin domain containing 1 |
| chr6_+_142468361 | 10.35 |
ENST00000367630.4
|
VTA1
|
vesicle (multivesicular body) trafficking 1 |
| chr11_+_65647280 | 10.32 |
ENST00000307886.3
ENST00000528419.1 ENST00000526034.1 |
CTSW
|
cathepsin W |
| chr2_+_143886877 | 10.31 |
ENST00000295095.6
|
ARHGAP15
|
Rho GTPase activating protein 15 |
| chr5_+_67588391 | 10.27 |
ENST00000523872.1
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr1_-_92951607 | 10.27 |
ENST00000427103.1
|
GFI1
|
growth factor independent 1 transcription repressor |
| chr7_+_99971129 | 10.20 |
ENST00000394000.2
ENST00000350573.2 |
PILRA
|
paired immunoglobin-like type 2 receptor alpha |
| chr3_+_113251143 | 10.19 |
ENST00000264852.4
ENST00000393830.3 |
SIDT1
|
SID1 transmembrane family, member 1 |
| chr11_+_2323349 | 10.17 |
ENST00000381121.3
|
TSPAN32
|
tetraspanin 32 |
| chr6_-_41168920 | 10.14 |
ENST00000483722.1
|
TREML2
|
triggering receptor expressed on myeloid cells-like 2 |
| chr3_-_187454281 | 10.14 |
ENST00000232014.4
|
BCL6
|
B-cell CLL/lymphoma 6 |
| chr3_+_122044084 | 10.13 |
ENST00000264474.3
ENST00000479204.1 |
CSTA
|
cystatin A (stefin A) |
| chr2_+_90273679 | 10.10 |
ENST00000423080.2
|
IGKV3D-7
|
immunoglobulin kappa variable 3D-7 |
| chr6_+_31554456 | 10.07 |
ENST00000339530.4
|
LST1
|
leukocyte specific transcript 1 |
| chr19_-_15529790 | 10.02 |
ENST00000596195.1
ENST00000595067.1 ENST00000595465.2 ENST00000397410.5 ENST00000600247.1 |
AKAP8L
|
A kinase (PRKA) anchor protein 8-like |
| chr3_+_57541975 | 10.01 |
ENST00000487257.1
ENST00000311180.8 |
PDE12
|
phosphodiesterase 12 |
| chr1_+_17634689 | 9.98 |
ENST00000375453.1
ENST00000375448.4 |
PADI4
|
peptidyl arginine deiminase, type IV |
| chr1_+_174843548 | 9.97 |
ENST00000478442.1
ENST00000465412.1 |
RABGAP1L
|
RAB GTPase activating protein 1-like |
| chr14_-_23285069 | 9.87 |
ENST00000554758.1
ENST00000397528.4 |
SLC7A7
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| chr2_+_89890533 | 9.81 |
ENST00000429992.2
|
IGKV2D-40
|
immunoglobulin kappa variable 2D-40 |
| chr8_-_19540266 | 9.73 |
ENST00000311540.4
|
CSGALNACT1
|
chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| chr19_-_2151523 | 9.71 |
ENST00000350812.6
ENST00000355272.6 ENST00000356926.4 ENST00000345016.5 |
AP3D1
|
adaptor-related protein complex 3, delta 1 subunit |
| chr6_-_152958521 | 9.70 |
ENST00000367255.5
ENST00000265368.4 ENST00000448038.1 ENST00000341594.5 |
SYNE1
|
spectrin repeat containing, nuclear envelope 1 |
| chr9_-_98079965 | 9.69 |
ENST00000289081.3
|
FANCC
|
Fanconi anemia, complementation group C |
| chr3_-_138763734 | 9.65 |
ENST00000413199.1
ENST00000502927.2 |
PRR23C
|
proline rich 23C |
| chr19_-_10445399 | 9.65 |
ENST00000592945.1
|
ICAM3
|
intercellular adhesion molecule 3 |
| chr19_-_42498369 | 9.63 |
ENST00000302102.5
ENST00000545399.1 |
ATP1A3
|
ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| chrX_-_70838306 | 9.54 |
ENST00000373691.4
ENST00000373693.3 |
CXCR3
|
chemokine (C-X-C motif) receptor 3 |
| chr19_-_18391708 | 9.54 |
ENST00000600972.1
|
JUND
|
jun D proto-oncogene |
| chr3_-_13009168 | 9.49 |
ENST00000273221.4
|
IQSEC1
|
IQ motif and Sec7 domain 1 |
| chr16_+_72088376 | 9.48 |
ENST00000570083.1
ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5 |
HP
HPR
|
haptoglobin haptoglobin-related protein |
| chrX_+_37639302 | 9.47 |
ENST00000545017.1
ENST00000536160.1 |
CYBB
|
cytochrome b-245, beta polypeptide |
| chr18_+_13612613 | 9.46 |
ENST00000586765.1
|
LDLRAD4
|
low density lipoprotein receptor class A domain containing 4 |
| chr22_+_22786288 | 9.43 |
ENST00000390301.2
|
IGLV1-36
|
immunoglobulin lambda variable 1-36 |
| chr1_-_207095324 | 9.40 |
ENST00000530505.1
ENST00000367091.3 ENST00000442471.2 |
FAIM3
|
Fas apoptotic inhibitory molecule 3 |
| chr2_-_175462934 | 9.36 |
ENST00000392546.2
ENST00000436221.1 |
WIPF1
|
WAS/WASL interacting protein family, member 1 |
| chrX_-_78622805 | 9.34 |
ENST00000373298.2
|
ITM2A
|
integral membrane protein 2A |
| chr5_+_75699040 | 9.29 |
ENST00000274364.6
|
IQGAP2
|
IQ motif containing GTPase activating protein 2 |
| chr12_+_7055767 | 9.25 |
ENST00000447931.2
|
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr11_-_58343319 | 9.22 |
ENST00000395074.2
|
LPXN
|
leupaxin |
| chr7_-_36634181 | 9.17 |
ENST00000538464.1
|
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr2_+_201980827 | 9.16 |
ENST00000309955.3
ENST00000443227.1 ENST00000341222.6 ENST00000355558.4 ENST00000340870.5 ENST00000341582.6 |
CFLAR
|
CASP8 and FADD-like apoptosis regulator |
| chr1_+_155829286 | 9.16 |
ENST00000368324.4
|
SYT11
|
synaptotagmin XI |
| chr15_+_25200074 | 9.12 |
ENST00000390687.4
ENST00000584968.1 ENST00000346403.6 ENST00000554227.2 |
SNRPN
|
small nuclear ribonucleoprotein polypeptide N |
Network of associatons between targets according to the STRING database.
First level regulatory network of RUNX1_RUNX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.9 | 62.6 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
| 14.5 | 43.6 | GO:1902997 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 13.6 | 13.6 | GO:2001190 | positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190) |
| 12.8 | 63.8 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 9.7 | 77.2 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 9.5 | 28.5 | GO:0001798 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
| 9.3 | 37.3 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 9.2 | 9.2 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 8.9 | 26.7 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 8.5 | 34.1 | GO:2000537 | regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 8.2 | 32.7 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 7.1 | 49.6 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 5.7 | 17.1 | GO:0002625 | regulation of T cell antigen processing and presentation(GO:0002625) |
| 5.7 | 45.3 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 5.7 | 22.6 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 5.6 | 16.7 | GO:1904884 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 5.5 | 11.0 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 5.5 | 21.9 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 5.4 | 16.1 | GO:0002818 | intracellular defense response(GO:0002818) |
| 4.9 | 14.6 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547) |
| 4.4 | 22.1 | GO:1904845 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 4.2 | 12.5 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 3.9 | 70.4 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 3.8 | 11.3 | GO:0090219 | negative regulation of lipid kinase activity(GO:0090219) |
| 3.7 | 11.2 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 3.7 | 11.1 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 3.6 | 10.8 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 3.5 | 17.6 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) |
| 3.5 | 17.4 | GO:0070778 | L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712) |
| 3.4 | 17.1 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 3.4 | 10.3 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 3.3 | 19.6 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 3.2 | 9.7 | GO:0042494 | detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 3.2 | 9.7 | GO:0036466 | synaptic vesicle recycling via endosome(GO:0036466) |
| 3.2 | 12.8 | GO:0002884 | negative regulation of hypersensitivity(GO:0002884) |
| 3.2 | 9.5 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 3.2 | 18.9 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822) |
| 3.0 | 3.0 | GO:0002590 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) |
| 3.0 | 11.9 | GO:2001193 | gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) |
| 3.0 | 17.9 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 2.9 | 61.8 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) |
| 2.9 | 8.7 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 2.8 | 16.8 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 2.8 | 27.6 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 2.7 | 8.1 | GO:1902523 | positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 2.6 | 18.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 2.6 | 39.0 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 2.6 | 10.3 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 2.6 | 7.7 | GO:0051595 | response to methylglyoxal(GO:0051595) |
| 2.6 | 28.2 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 2.5 | 7.5 | GO:1901731 | positive regulation of platelet aggregation(GO:1901731) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 2.5 | 7.4 | GO:0090035 | regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
| 2.5 | 7.4 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 2.5 | 22.1 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308) |
| 2.4 | 7.1 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 2.3 | 7.0 | GO:0039506 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 2.3 | 32.2 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 2.2 | 8.9 | GO:0019046 | release from viral latency(GO:0019046) |
| 2.2 | 19.9 | GO:1903416 | response to glycoside(GO:1903416) |
| 2.2 | 8.8 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 2.2 | 10.8 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 2.1 | 10.7 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 2.1 | 23.6 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 2.1 | 25.3 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 2.1 | 6.3 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 2.1 | 6.3 | GO:1900226 | negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) |
| 2.1 | 8.3 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 2.1 | 24.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 2.0 | 14.3 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 2.0 | 10.0 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
| 2.0 | 8.0 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
| 2.0 | 13.7 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 2.0 | 23.4 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 1.9 | 17.5 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
| 1.9 | 27.1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
| 1.9 | 3.9 | GO:0090306 | oocyte maturation(GO:0001556) spindle assembly involved in female meiosis(GO:0007056) spindle assembly involved in meiosis(GO:0090306) |
| 1.9 | 13.5 | GO:0045007 | depurination(GO:0045007) |
| 1.9 | 264.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 1.8 | 5.5 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 1.8 | 7.4 | GO:0060313 | negative regulation of blood vessel remodeling(GO:0060313) |
| 1.8 | 11.0 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 1.8 | 7.3 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 1.8 | 25.4 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 1.8 | 3.6 | GO:2000566 | positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) |
| 1.8 | 14.5 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 1.8 | 7.2 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 1.8 | 26.6 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.7 | 5.2 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 1.7 | 5.2 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 1.7 | 5.1 | GO:1904597 | regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204) |
| 1.7 | 5.1 | GO:0033212 | iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308) |
| 1.7 | 10.1 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 1.7 | 6.7 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 1.7 | 19.8 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 1.6 | 13.1 | GO:0015705 | iodide transport(GO:0015705) |
| 1.6 | 21.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 1.6 | 11.4 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 1.6 | 4.9 | GO:1903027 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
| 1.6 | 3.2 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.6 | 4.8 | GO:1904617 | negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617) |
| 1.6 | 56.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 1.6 | 4.7 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 1.6 | 9.3 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
| 1.5 | 4.6 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 1.5 | 4.6 | GO:0072218 | ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218) |
| 1.5 | 15.2 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 1.5 | 4.5 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 1.5 | 16.4 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 1.5 | 4.4 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
| 1.5 | 4.4 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
| 1.5 | 4.4 | GO:0007538 | primary sex determination(GO:0007538) |
| 1.5 | 4.4 | GO:0045643 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 1.5 | 10.2 | GO:0033227 | dsRNA transport(GO:0033227) |
| 1.4 | 2.9 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 1.4 | 12.9 | GO:0072017 | distal tubule development(GO:0072017) |
| 1.4 | 1.4 | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) |
| 1.4 | 2.9 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 1.4 | 99.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 1.4 | 11.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 1.4 | 4.2 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 1.4 | 2.8 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
| 1.4 | 4.1 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 1.3 | 5.3 | GO:0003172 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 1.3 | 5.2 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 1.3 | 3.9 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 1.3 | 5.1 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 1.3 | 7.7 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 1.3 | 1.3 | GO:0001810 | regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068) |
| 1.3 | 3.8 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 1.3 | 3.8 | GO:0002032 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) |
| 1.3 | 3.8 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 1.3 | 3.8 | GO:0007518 | myoblast fate determination(GO:0007518) |
| 1.2 | 3.7 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 1.2 | 6.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 1.2 | 7.3 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 1.2 | 7.3 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 1.2 | 3.6 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 1.2 | 8.3 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 1.2 | 3.5 | GO:1900106 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 1.2 | 10.4 | GO:0050862 | positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 1.1 | 4.6 | GO:1905073 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075) |
| 1.1 | 3.4 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
| 1.1 | 13.7 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 1.1 | 13.6 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 1.1 | 4.5 | GO:0002266 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
| 1.1 | 9.0 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 1.1 | 3.4 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 1.1 | 11.1 | GO:0002223 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 1.1 | 13.2 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 1.1 | 22.0 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 1.1 | 4.4 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 1.1 | 15.2 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 1.1 | 4.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 1.1 | 8.6 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
| 1.1 | 22.4 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 1.1 | 11.7 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 1.1 | 7.5 | GO:0070269 | pyroptosis(GO:0070269) |
| 1.0 | 16.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 1.0 | 3.1 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 1.0 | 2.1 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 1.0 | 4.1 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 1.0 | 7.2 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 1.0 | 1.0 | GO:0048290 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) |
| 1.0 | 5.1 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 1.0 | 2.0 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 1.0 | 3.0 | GO:0016045 | detection of bacterium(GO:0016045) cellular response to muramyl dipeptide(GO:0071225) |
| 1.0 | 3.0 | GO:1904640 | response to methionine(GO:1904640) |
| 1.0 | 1.0 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 1.0 | 7.7 | GO:0009304 | tRNA transcription(GO:0009304) |
| 1.0 | 5.7 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 1.0 | 12.4 | GO:1904896 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 1.0 | 1.0 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 1.0 | 2.9 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.9 | 10.3 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.9 | 3.7 | GO:0048749 | compound eye development(GO:0048749) |
| 0.9 | 2.8 | GO:0033861 | negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.9 | 8.4 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.9 | 2.8 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.9 | 13.6 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.9 | 1.8 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) |
| 0.9 | 10.8 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.9 | 4.5 | GO:0090649 | rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.9 | 7.1 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.9 | 3.6 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.9 | 13.3 | GO:0022010 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.9 | 8.9 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.9 | 9.7 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.9 | 2.6 | GO:0035696 | monocyte extravasation(GO:0035696) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437) |
| 0.9 | 7.9 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.9 | 7.8 | GO:0034088 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 0.9 | 7.7 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.9 | 4.3 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.9 | 2.6 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.9 | 8.5 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.8 | 3.4 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
| 0.8 | 0.8 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.8 | 2.5 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.8 | 5.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.8 | 4.9 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.8 | 4.1 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.8 | 4.0 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.8 | 1.6 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.8 | 5.6 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.8 | 7.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.8 | 1.6 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.8 | 3.9 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.8 | 3.1 | GO:0097411 | hypoxia-inducible factor-1alpha signaling pathway(GO:0097411) |
| 0.8 | 7.7 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.8 | 3.8 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.8 | 2.3 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.8 | 3.1 | GO:0030242 | pexophagy(GO:0030242) |
| 0.8 | 35.0 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.8 | 3.0 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.8 | 2.3 | GO:2000870 | regulation of progesterone secretion(GO:2000870) |
| 0.8 | 1.5 | GO:0050955 | thermoception(GO:0050955) |
| 0.8 | 3.0 | GO:0071673 | positive regulation of smooth muscle cell chemotaxis(GO:0071673) response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.7 | 13.5 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.7 | 6.0 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 0.7 | 3.7 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.7 | 3.0 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.7 | 5.9 | GO:0048793 | pronephros development(GO:0048793) |
| 0.7 | 2.2 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.7 | 0.7 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.7 | 4.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.7 | 94.3 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.7 | 2.9 | GO:0006050 | mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051) |
| 0.7 | 1.4 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.7 | 5.7 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.7 | 5.7 | GO:0045656 | negative regulation of monocyte differentiation(GO:0045656) |
| 0.7 | 5.0 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.7 | 1.4 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
| 0.7 | 3.5 | GO:0009595 | detection of biotic stimulus(GO:0009595) |
| 0.7 | 1.4 | GO:0048484 | enteric nervous system development(GO:0048484) |
| 0.7 | 2.1 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.7 | 4.8 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.7 | 11.5 | GO:0030947 | regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947) |
| 0.7 | 4.0 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.7 | 3.3 | GO:0099540 | synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) |
| 0.7 | 3.3 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
| 0.7 | 0.7 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.7 | 2.0 | GO:0044278 | cell wall disruption in other organism(GO:0044278) |
| 0.7 | 14.6 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.7 | 2.7 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.7 | 6.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.7 | 21.7 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.7 | 2.6 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.6 | 6.4 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.6 | 57.0 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.6 | 10.8 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.6 | 1.9 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.6 | 6.3 | GO:0090128 | regulation of synapse maturation(GO:0090128) |
| 0.6 | 1.3 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.6 | 3.1 | GO:2000301 | myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.6 | 14.3 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.6 | 6.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.6 | 15.9 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.6 | 4.9 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.6 | 9.2 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.6 | 4.9 | GO:1905097 | protein localization to endoplasmic reticulum exit site(GO:0070973) regulation of guanyl-nucleotide exchange factor activity(GO:1905097) |
| 0.6 | 3.0 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
| 0.6 | 3.0 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.6 | 9.5 | GO:0006071 | glycerol metabolic process(GO:0006071) |
| 0.6 | 4.7 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.6 | 1.8 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.6 | 24.2 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.6 | 4.1 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.6 | 5.3 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
| 0.6 | 1.2 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.6 | 2.3 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
| 0.6 | 4.6 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.6 | 5.8 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.6 | 10.4 | GO:0098743 | cell aggregation(GO:0098743) |
| 0.6 | 4.6 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.6 | 2.3 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.6 | 0.6 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.6 | 1.7 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.6 | 7.4 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.6 | 7.8 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.6 | 36.9 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.5 | 1.6 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) |
| 0.5 | 4.9 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.5 | 3.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.5 | 4.3 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.5 | 1.6 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
| 0.5 | 10.6 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.5 | 9.5 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.5 | 8.3 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.5 | 19.2 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.5 | 2.1 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.5 | 8.7 | GO:0019374 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.5 | 1.5 | GO:0016999 | antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605) |
| 0.5 | 14.3 | GO:0007616 | long-term memory(GO:0007616) |
| 0.5 | 3.0 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.5 | 1.0 | GO:1901911 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.5 | 5.0 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.5 | 1.5 | GO:0071934 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.5 | 5.5 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.5 | 36.1 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.5 | 2.5 | GO:0000920 | cell separation after cytokinesis(GO:0000920) negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.5 | 10.1 | GO:0071593 | lymphocyte aggregation(GO:0071593) |
| 0.5 | 4.3 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.5 | 2.9 | GO:0001661 | conditioned taste aversion(GO:0001661) amygdala development(GO:0021764) |
| 0.5 | 3.3 | GO:0023014 | signal transduction by protein phosphorylation(GO:0023014) |
| 0.5 | 6.1 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.5 | 3.7 | GO:0032306 | regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) |
| 0.5 | 6.0 | GO:0010248 | establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) sodium ion export from cell(GO:0036376) potassium ion import across plasma membrane(GO:1990573) |
| 0.4 | 5.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.4 | 1.8 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
| 0.4 | 8.8 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.4 | 1.3 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.4 | 0.9 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.4 | 5.7 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.4 | 3.0 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 0.4 | 3.0 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.4 | 6.8 | GO:0042574 | retinal metabolic process(GO:0042574) |
| 0.4 | 24.7 | GO:0050672 | negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664) |
| 0.4 | 1.7 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.4 | 2.5 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.4 | 1.6 | GO:0009386 | translational attenuation(GO:0009386) |
| 0.4 | 1.2 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
| 0.4 | 2.4 | GO:0071104 | response to interleukin-9(GO:0071104) |
| 0.4 | 2.4 | GO:0045072 | regulation of interferon-gamma biosynthetic process(GO:0045072) |
| 0.4 | 5.6 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.4 | 6.4 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.4 | 1.6 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.4 | 11.5 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.4 | 16.7 | GO:0006536 | glutamate metabolic process(GO:0006536) |
| 0.4 | 3.1 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.4 | 1.5 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.4 | 6.9 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 0.4 | 3.1 | GO:0045023 | G0 to G1 transition(GO:0045023) |
| 0.4 | 0.4 | GO:0032714 | negative regulation of interleukin-5 production(GO:0032714) |
| 0.4 | 6.4 | GO:0042036 | negative regulation of cytokine biosynthetic process(GO:0042036) |
| 0.4 | 1.5 | GO:0050705 | negative regulation of interleukin-1 alpha production(GO:0032690) regulation of interleukin-1 alpha secretion(GO:0050705) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 0.4 | 11.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.4 | 3.0 | GO:0021546 | rhombomere development(GO:0021546) |
| 0.4 | 2.6 | GO:0045471 | response to ethanol(GO:0045471) |
| 0.4 | 7.0 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.4 | 1.5 | GO:0060322 | head development(GO:0060322) |
| 0.4 | 10.7 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.4 | 1.5 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.4 | 2.2 | GO:0034626 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.4 | 4.3 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.4 | 3.9 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.3 | 5.1 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.3 | 1.4 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
| 0.3 | 13.3 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.3 | 2.0 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.3 | 3.0 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.3 | 1.7 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.3 | 3.7 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.3 | 3.6 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.3 | 5.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.3 | 1.3 | GO:0060283 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
| 0.3 | 6.2 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.3 | 5.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.3 | 2.3 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.3 | 3.5 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.3 | 1.6 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.3 | 2.5 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.3 | 2.5 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.3 | 5.7 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.3 | 1.6 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.3 | 1.9 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.3 | 0.6 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.3 | 2.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.3 | 4.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.3 | 1.5 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.3 | 4.0 | GO:0007567 | parturition(GO:0007567) |
| 0.3 | 10.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.3 | 19.6 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 0.3 | 3.6 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.3 | 12.8 | GO:0030101 | natural killer cell activation(GO:0030101) |
| 0.3 | 4.4 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.3 | 3.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.3 | 1.2 | GO:0010761 | fibroblast migration(GO:0010761) |
| 0.3 | 6.6 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.3 | 0.6 | GO:0006522 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) |
| 0.3 | 0.6 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
| 0.3 | 12.1 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
| 0.3 | 7.6 | GO:0009967 | positive regulation of signal transduction(GO:0009967) |
| 0.3 | 10.0 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.3 | 4.2 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.3 | 2.7 | GO:1901739 | regulation of myoblast fusion(GO:1901739) |
| 0.3 | 0.5 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.3 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.3 | 0.8 | GO:0050757 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.3 | 3.5 | GO:0021702 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.3 | 2.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.3 | 3.7 | GO:1903817 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.3 | 3.3 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.3 | 2.8 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.3 | 20.4 | GO:0021510 | spinal cord development(GO:0021510) |
| 0.2 | 3.7 | GO:0090314 | positive regulation of protein targeting to membrane(GO:0090314) |
| 0.2 | 21.7 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.2 | 2.7 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.2 | 4.3 | GO:0045199 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 2.6 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.2 | 9.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.2 | 0.9 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.2 | 2.6 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
| 0.2 | 8.4 | GO:0042417 | dopamine metabolic process(GO:0042417) |
| 0.2 | 8.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.2 | 4.4 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.2 | 7.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 1.2 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.2 | 5.5 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.2 | 5.5 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.2 | 4.2 | GO:0006768 | biotin metabolic process(GO:0006768) |
| 0.2 | 1.1 | GO:0061370 | testosterone biosynthetic process(GO:0061370) |
| 0.2 | 2.6 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.2 | 0.4 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
| 0.2 | 1.3 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.2 | 1.3 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.2 | 2.8 | GO:0048011 | neurotrophin TRK receptor signaling pathway(GO:0048011) |
| 0.2 | 0.8 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
| 0.2 | 2.3 | GO:0051904 | melanosome transport(GO:0032402) pigment granule transport(GO:0051904) |
| 0.2 | 1.0 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.2 | 7.7 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.2 | 1.0 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
| 0.2 | 6.0 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 6.6 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.2 | 2.7 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 0.2 | 2.6 | GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) |
| 0.2 | 9.3 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.2 | 4.3 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.2 | 2.0 | GO:0070977 | bone maturation(GO:0070977) |
| 0.2 | 1.6 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.2 | 1.6 | GO:0051775 | response to redox state(GO:0051775) |
| 0.2 | 1.2 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.2 | 1.7 | GO:0030324 | lung development(GO:0030324) |
| 0.2 | 0.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.2 | 0.8 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.2 | 3.1 | GO:1901216 | positive regulation of neuron death(GO:1901216) |
| 0.2 | 1.1 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.2 | 7.8 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 7.1 | GO:0005975 | carbohydrate metabolic process(GO:0005975) |
| 0.2 | 2.7 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.2 | 3.6 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.2 | 0.7 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.2 | 3.9 | GO:0043536 | positive regulation of blood vessel endothelial cell migration(GO:0043536) |
| 0.2 | 4.4 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.2 | 2.3 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.2 | 1.0 | GO:0007320 | insemination(GO:0007320) |
| 0.2 | 5.7 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.2 | 10.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.2 | 3.0 | GO:0033198 | response to ATP(GO:0033198) |
| 0.2 | 2.7 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.2 | 6.5 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.2 | 0.8 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 0.3 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 0.2 | 1.6 | GO:1901889 | negative regulation of cell junction assembly(GO:1901889) |
| 0.2 | 1.5 | GO:0010801 | negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.2 | 2.4 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.2 | 1.6 | GO:0015937 | coenzyme A metabolic process(GO:0015936) coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 2.8 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.2 | 1.7 | GO:0006228 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.2 | 0.5 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.2 | 3.9 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 15.5 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.1 | 0.9 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.7 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.1 | 3.2 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.1 | 36.4 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.1 | 20.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 2.2 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.1 | 15.4 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.1 | 3.2 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 0.9 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.5 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.1 | 0.4 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528) |
| 0.1 | 6.5 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.1 | 3.7 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.1 | 2.1 | GO:0003197 | endocardial cushion development(GO:0003197) |
| 0.1 | 3.0 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.1 | 1.0 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.1 | 1.1 | GO:0003228 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
| 0.1 | 0.7 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393) |
| 0.1 | 0.9 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.1 | 0.3 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.1 | 0.2 | GO:0010656 | negative regulation of muscle cell apoptotic process(GO:0010656) |
| 0.1 | 3.1 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.1 | 2.3 | GO:0007032 | endosome organization(GO:0007032) |
| 0.1 | 0.8 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.1 | 1.7 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 0.9 | GO:0090280 | positive regulation of calcium ion import(GO:0090280) |
| 0.1 | 9.6 | GO:0050680 | negative regulation of epithelial cell proliferation(GO:0050680) |
| 0.1 | 0.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 1.0 | GO:0043578 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 1.7 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.1 | 3.9 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 0.7 | GO:0036155 | acylglycerol acyl-chain remodeling(GO:0036155) regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 4.9 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.1 | 4.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 1.3 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 1.3 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 3.2 | GO:0006898 | receptor-mediated endocytosis(GO:0006898) |
| 0.1 | 3.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.1 | 0.4 | GO:0030432 | peristalsis(GO:0030432) somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 0.1 | 1.8 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.1 | 1.0 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.1 | 3.8 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.1 | 0.2 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.1 | 1.1 | GO:0031935 | regulation of chromatin silencing(GO:0031935) |
| 0.1 | 0.9 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.1 | 0.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 1.0 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.1 | 2.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 0.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.1 | 0.6 | GO:0009410 | response to xenobiotic stimulus(GO:0009410) |
| 0.1 | 1.1 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.1 | 2.5 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.1 | 0.5 | GO:0044241 | lipid digestion(GO:0044241) |
| 0.1 | 1.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.1 | 0.2 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.0 | 0.0 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.0 | 0.3 | GO:1990118 | gastric acid secretion(GO:0001696) sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 2.8 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 0.2 | GO:0030208 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.4 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.7 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.7 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
| 0.0 | 0.6 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 1.4 | GO:0007270 | neuron-neuron synaptic transmission(GO:0007270) |
| 0.0 | 2.9 | GO:0007265 | Ras protein signal transduction(GO:0007265) |
| 0.0 | 0.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.2 | GO:0045779 | negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851) |
| 0.0 | 0.5 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.0 | 0.2 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.0 | 0.2 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.9 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.0 | 2.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.6 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
| 0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.2 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 0.2 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.4 | 43.3 | GO:0071749 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 8.3 | 33.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 8.2 | 32.7 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 5.4 | 37.6 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 4.5 | 27.1 | GO:1990037 | Lewy body core(GO:1990037) |
| 4.4 | 13.3 | GO:0097453 | mesaxon(GO:0097453) ensheathing process(GO:1990015) |
| 4.1 | 20.6 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 3.9 | 81.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 3.7 | 74.1 | GO:0001891 | phagocytic cup(GO:0001891) |
| 3.6 | 17.9 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 3.2 | 9.7 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 3.0 | 21.1 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 2.9 | 8.8 | GO:0071020 | post-spliceosomal complex(GO:0071020) |
| 2.9 | 14.3 | GO:0001652 | granular component(GO:0001652) |
| 2.6 | 2.6 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.6 | 10.3 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 2.5 | 10.1 | GO:1990246 | uniplex complex(GO:1990246) |
| 2.4 | 7.3 | GO:0036398 | TCR signalosome(GO:0036398) |
| 2.4 | 16.6 | GO:0033269 | internode region of axon(GO:0033269) |
| 2.4 | 14.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 2.2 | 24.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 2.1 | 37.7 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 2.0 | 14.1 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 2.0 | 10.0 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.8 | 7.1 | GO:0071062 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 1.7 | 8.7 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.7 | 25.2 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 1.7 | 28.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 1.5 | 22.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 1.5 | 32.0 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 1.4 | 65.8 | GO:0019814 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 1.4 | 5.5 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 1.3 | 1.3 | GO:0071439 | clathrin complex(GO:0071439) |
| 1.3 | 20.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 1.3 | 22.1 | GO:0005687 | U4 snRNP(GO:0005687) |
| 1.3 | 7.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 1.3 | 6.3 | GO:0089701 | U2AF(GO:0089701) |
| 1.3 | 5.1 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 1.2 | 9.5 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.1 | 10.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 1.1 | 4.5 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 1.1 | 13.5 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 1.1 | 4.5 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 1.0 | 3.1 | GO:0034271 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 1.0 | 43.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 1.0 | 7.7 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 1.0 | 7.7 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.9 | 8.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.9 | 31.5 | GO:0008305 | integrin complex(GO:0008305) |
| 0.9 | 8.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.9 | 7.9 | GO:0097433 | dense body(GO:0097433) |
| 0.9 | 9.5 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.9 | 9.4 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.9 | 91.2 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.8 | 7.8 | GO:0044754 | autolysosome(GO:0044754) |
| 0.8 | 68.5 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.8 | 3.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.7 | 6.7 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.7 | 12.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.7 | 33.5 | GO:0002102 | podosome(GO:0002102) |
| 0.7 | 8.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.7 | 10.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.7 | 2.6 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.6 | 4.5 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.6 | 3.7 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.6 | 4.3 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.6 | 3.7 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.6 | 4.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.6 | 10.8 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.6 | 5.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.6 | 1.2 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.6 | 2.9 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.6 | 85.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.6 | 2.9 | GO:0044308 | axonal spine(GO:0044308) |
| 0.6 | 12.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.6 | 12.2 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.6 | 3.9 | GO:0072487 | MSL complex(GO:0072487) |
| 0.6 | 10.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.6 | 8.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.5 | 4.9 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
| 0.5 | 2.7 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.5 | 28.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.5 | 3.7 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.5 | 2.7 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.5 | 6.3 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.5 | 3.7 | GO:0097361 | CIA complex(GO:0097361) |
| 0.5 | 123.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.5 | 2.5 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.5 | 5.4 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.5 | 54.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.5 | 6.1 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.5 | 3.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.5 | 20.8 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.5 | 5.5 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.4 | 1.8 | GO:0005797 | Golgi trans cisterna(GO:0000138) Golgi medial cisterna(GO:0005797) |
| 0.4 | 11.1 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.4 | 5.3 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.4 | 1.3 | GO:0070083 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.4 | 3.9 | GO:0045261 | proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.4 | 15.4 | GO:0000791 | euchromatin(GO:0000791) |
| 0.4 | 2.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.4 | 29.7 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.4 | 3.7 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.4 | 17.3 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.4 | 2.3 | GO:0034464 | BBSome(GO:0034464) |
| 0.4 | 3.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.4 | 6.1 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.4 | 3.0 | GO:0000243 | commitment complex(GO:0000243) |
| 0.4 | 7.4 | GO:0005903 | brush border(GO:0005903) |
| 0.4 | 3.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.4 | 1.8 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.4 | 2.9 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.4 | 26.6 | GO:0005901 | caveola(GO:0005901) |
| 0.3 | 21.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.3 | 4.3 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 7.7 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.3 | 5.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.3 | 4.2 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.3 | 5.1 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 2.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.3 | 1.6 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.3 | 1.9 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 3.3 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.3 | 6.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.3 | 36.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 0.9 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.3 | 15.4 | GO:0005938 | cell cortex(GO:0005938) |
| 0.3 | 16.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.3 | 26.7 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.3 | 0.8 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.3 | 7.8 | GO:0016235 | aggresome(GO:0016235) |
| 0.3 | 6.2 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.3 | 0.8 | GO:0071437 | invadopodium(GO:0071437) |
| 0.2 | 2.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 15.0 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 6.0 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.2 | 19.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.2 | 0.7 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.2 | 12.7 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.2 | 1.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.2 | 2.8 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.2 | 11.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.2 | 4.2 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.2 | 1.0 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.2 | 2.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.2 | 63.5 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.2 | 0.6 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 9.1 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.2 | 12.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.2 | 2.4 | GO:0031430 | M band(GO:0031430) |
| 0.2 | 1.0 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.2 | 2.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.2 | 1.9 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 0.2 | 2.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.2 | 26.0 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.2 | 3.7 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.2 | 4.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 6.8 | GO:0005776 | autophagosome(GO:0005776) |
| 0.2 | 9.7 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.2 | 8.6 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.2 | 20.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 1.3 | GO:0045180 | basal cortex(GO:0045180) |
| 0.2 | 0.6 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 11.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 230.0 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.2 | 6.8 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 1.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 19.2 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.1 | 1.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 1.0 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 1.3 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 3.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 6.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 3.3 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.1 | 11.5 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.1 | 14.3 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 2.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 1.2 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.1 | 5.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 4.2 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 2.5 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 0.5 | GO:0030663 | COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663) |
| 0.1 | 1.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 2.6 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 3.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 6.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 2.0 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 3.0 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 177.4 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.1 | 4.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 0.6 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.1 | 0.2 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.1 | 4.4 | GO:0031970 | organelle envelope lumen(GO:0031970) |
| 0.1 | 2.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 1.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 67.6 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 1.1 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 1.3 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.4 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.3 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.5 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 3.8 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 0.9 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.9 | 62.6 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
| 11.0 | 22.1 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 8.8 | 26.5 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 8.8 | 26.4 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 7.5 | 22.6 | GO:0008955 | peptidoglycan glycosyltransferase activity(GO:0008955) |
| 5.8 | 40.3 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 5.2 | 15.5 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 5.0 | 45.3 | GO:0043426 | MRF binding(GO:0043426) |
| 4.6 | 64.8 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 4.2 | 12.7 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 4.1 | 16.3 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 3.7 | 11.1 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 3.6 | 10.8 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 3.5 | 17.4 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 3.4 | 17.0 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 3.2 | 9.7 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 3.2 | 9.5 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 3.1 | 48.8 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 3.0 | 3.0 | GO:0042806 | fucose binding(GO:0042806) |
| 3.0 | 11.9 | GO:0030107 | HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) |
| 2.9 | 23.2 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 2.9 | 77.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 2.8 | 11.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 2.8 | 16.7 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 2.6 | 10.4 | GO:0047708 | biotinidase activity(GO:0047708) |
| 2.6 | 17.9 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 2.6 | 7.7 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 2.5 | 20.0 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 2.5 | 44.2 | GO:0005522 | profilin binding(GO:0005522) |
| 2.4 | 9.7 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 2.4 | 9.5 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 2.4 | 7.1 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 2.3 | 9.4 | GO:0032406 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 2.2 | 15.1 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 2.1 | 42.9 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 2.1 | 23.6 | GO:0004568 | chitinase activity(GO:0004568) chitin binding(GO:0008061) |
| 2.1 | 8.6 | GO:0004803 | transposase activity(GO:0004803) |
| 2.1 | 10.6 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 2.1 | 8.3 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 2.1 | 6.2 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 2.1 | 10.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 2.0 | 26.6 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 2.0 | 8.1 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 2.0 | 8.0 | GO:0032396 | inhibitory MHC class I receptor activity(GO:0032396) |
| 2.0 | 5.9 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 1.9 | 7.8 | GO:0005502 | 11-cis retinal binding(GO:0005502) |
| 1.9 | 3.9 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 1.9 | 7.6 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.9 | 18.9 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 1.9 | 15.1 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 1.9 | 7.4 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 1.9 | 22.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 1.8 | 5.4 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 1.8 | 26.7 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 1.7 | 13.9 | GO:0004875 | complement receptor activity(GO:0004875) |
| 1.7 | 10.4 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 1.7 | 48.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 1.7 | 5.1 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
| 1.7 | 10.2 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 1.7 | 13.6 | GO:0005534 | galactose binding(GO:0005534) |
| 1.7 | 6.8 | GO:0017040 | ceramidase activity(GO:0017040) |
| 1.6 | 16.4 | GO:0030884 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 1.6 | 8.0 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 1.6 | 22.1 | GO:0033691 | sialic acid binding(GO:0033691) |
| 1.6 | 25.0 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 1.5 | 318.4 | GO:0003823 | antigen binding(GO:0003823) |
| 1.5 | 15.2 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 1.5 | 4.5 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 1.5 | 7.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 1.5 | 4.4 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 1.4 | 4.3 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 1.4 | 2.8 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 1.4 | 16.7 | GO:0019864 | IgG binding(GO:0019864) |
| 1.4 | 8.3 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 1.4 | 6.9 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 1.4 | 4.1 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.4 | 4.1 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 1.3 | 18.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 1.3 | 3.9 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 1.3 | 5.2 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 1.3 | 3.9 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 1.3 | 6.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 1.3 | 15.2 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 1.2 | 4.9 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 1.2 | 5.9 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 1.2 | 3.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.2 | 37.0 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 1.1 | 10.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.1 | 6.7 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 1.1 | 5.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.1 | 9.8 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 1.1 | 21.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 1.1 | 18.0 | GO:0043274 | phospholipase binding(GO:0043274) |
| 1.0 | 8.3 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 1.0 | 20.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 1.0 | 5.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 1.0 | 12.1 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 1.0 | 1.0 | GO:0050072 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) m7G(5')pppN diphosphatase activity(GO:0050072) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 1.0 | 3.0 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 1.0 | 25.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 1.0 | 2.9 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 1.0 | 1.9 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 1.0 | 5.7 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.9 | 6.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.9 | 2.8 | GO:0035276 | ethanol binding(GO:0035276) |
| 0.9 | 38.4 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.9 | 4.5 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.9 | 8.9 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.9 | 3.5 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.9 | 9.5 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.9 | 20.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.9 | 13.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.9 | 16.2 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.8 | 4.2 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.8 | 6.7 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.8 | 7.5 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.8 | 5.8 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.8 | 4.0 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.8 | 1.6 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.8 | 61.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.8 | 3.9 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.8 | 3.9 | GO:0043532 | angiostatin binding(GO:0043532) |
| 0.8 | 3.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.8 | 2.3 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.7 | 1.5 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) azole transmembrane transporter activity(GO:1901474) |
| 0.7 | 2.9 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.7 | 4.3 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.7 | 5.6 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.7 | 2.8 | GO:0019862 | IgA binding(GO:0019862) |
| 0.7 | 2.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.7 | 16.9 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.7 | 4.7 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.7 | 3.3 | GO:0060175 | brain-derived neurotrophic factor-activated receptor activity(GO:0060175) |
| 0.7 | 8.0 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.7 | 3.3 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.7 | 3.3 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.7 | 7.3 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.7 | 2.7 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.7 | 6.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.7 | 4.6 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.7 | 27.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.6 | 2.6 | GO:0035473 | lipase binding(GO:0035473) |
| 0.6 | 143.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.6 | 16.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.6 | 10.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.6 | 1.9 | GO:0004833 | tryptophan 2,3-dioxygenase activity(GO:0004833) |
| 0.6 | 6.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.6 | 4.3 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.6 | 7.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.6 | 4.8 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.6 | 12.5 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.6 | 11.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.6 | 5.9 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
| 0.6 | 83.5 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.6 | 7.1 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.6 | 2.9 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.6 | 1.2 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.6 | 1.7 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.6 | 7.5 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.6 | 4.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.6 | 1.1 | GO:0050294 | steroid sulfotransferase activity(GO:0050294) |
| 0.6 | 12.6 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.6 | 5.6 | GO:0051378 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
| 0.6 | 5.0 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.5 | 2.7 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.5 | 7.0 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.5 | 1.6 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.5 | 2.7 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.5 | 6.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.5 | 5.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.5 | 6.6 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.5 | 3.0 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.5 | 3.0 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.5 | 10.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.5 | 5.0 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.5 | 15.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.5 | 7.9 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.5 | 14.1 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.5 | 7.7 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.5 | 8.2 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.5 | 34.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.5 | 37.5 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.5 | 4.8 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.5 | 3.3 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.5 | 1.4 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.5 | 2.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.5 | 5.9 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.5 | 5.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.4 | 3.6 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.4 | 2.7 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.4 | 9.7 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.4 | 1.3 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.4 | 22.0 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.4 | 6.1 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.4 | 9.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.4 | 9.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.4 | 3.6 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.4 | 13.4 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.4 | 1.6 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.4 | 1.6 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.4 | 1.5 | GO:0042020 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.4 | 3.8 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.4 | 1.5 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
| 0.4 | 6.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.4 | 2.9 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.4 | 2.2 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.4 | 10.3 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.4 | 6.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.4 | 8.1 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.3 | 3.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.3 | 3.8 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.3 | 2.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.3 | 3.8 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.3 | 7.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.3 | 2.3 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
| 0.3 | 12.9 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.3 | 2.6 | GO:0019199 | transmembrane receptor protein kinase activity(GO:0019199) |
| 0.3 | 1.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.3 | 8.2 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.3 | 17.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.3 | 3.4 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.3 | 2.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.3 | 1.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.3 | 5.1 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.3 | 1.5 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.3 | 10.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.3 | 5.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.3 | 2.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 2.0 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.3 | 9.4 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.3 | 4.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.3 | 0.6 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.3 | 12.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.3 | 10.9 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.3 | 1.1 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.3 | 1.9 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.3 | 5.1 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.3 | 7.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.3 | 7.1 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.3 | 4.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.3 | 2.8 | GO:0036122 | BMP binding(GO:0036122) |
| 0.3 | 93.1 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.2 | 1.0 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.2 | 2.4 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 0.7 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.2 | 1.0 | GO:0004356 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.2 | 0.5 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 16.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.2 | 8.2 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 0.9 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.2 | 1.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.2 | 3.4 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.2 | 3.6 | GO:0016405 | CoA-ligase activity(GO:0016405) |
| 0.2 | 3.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.2 | 0.9 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.2 | 2.9 | GO:0019825 | oxygen binding(GO:0019825) |
| 0.2 | 1.1 | GO:0016918 | retinal binding(GO:0016918) |
| 0.2 | 3.1 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.2 | 1.3 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 1.7 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 3.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.2 | 2.1 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.2 | 13.6 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.2 | 1.0 | GO:0031782 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.2 | 18.7 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.2 | 1.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.2 | 0.6 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.2 | 8.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.2 | 2.1 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.2 | 2.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 3.0 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.2 | 1.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.2 | 1.6 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.2 | 1.1 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.2 | 1.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
| 0.2 | 4.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.2 | 2.8 | GO:0034979 | NAD-dependent protein deacetylase activity(GO:0034979) |
| 0.2 | 1.8 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.2 | 2.3 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.2 | 16.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.2 | 4.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.2 | 3.6 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 3.7 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.2 | 1.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.2 | 3.1 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.2 | 1.0 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.2 | 1.6 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.2 | 1.0 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.2 | 1.7 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.2 | 1.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 2.0 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 2.7 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 2.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 2.7 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.1 | 13.3 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.1 | 0.7 | GO:0005319 | lipid transporter activity(GO:0005319) |
| 0.1 | 3.1 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 1.8 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.1 | 0.4 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.1 | 19.4 | GO:0004871 | signal transducer activity(GO:0004871) |
| 0.1 | 2.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.1 | 2.2 | GO:0005506 | iron ion binding(GO:0005506) |
| 0.1 | 1.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 2.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 2.1 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 2.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 11.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 3.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 14.3 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 0.1 | 2.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.1 | 5.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.9 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.1 | 0.8 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 0.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 0.8 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 0.5 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 2.0 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 2.0 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 4.3 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 3.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 1.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.2 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 0.1 | 1.0 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 2.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 1.0 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.1 | 0.2 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.1 | 1.1 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 3.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 5.6 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.1 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 1.6 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 6.2 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 1.2 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.8 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 2.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.2 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 2.4 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 0.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 0.5 | GO:0019841 | retinol binding(GO:0019841) |
| 0.1 | 1.2 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 1.6 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 0.2 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972) |
| 0.1 | 1.1 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 1.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.2 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 0.0 | 1.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 5.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 2.3 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.3 | GO:0055103 | ligase regulator activity(GO:0055103) |
| 0.0 | 0.6 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.0 | 0.6 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 3.8 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.7 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.4 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.6 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 0.2 | GO:0005372 | water transmembrane transporter activity(GO:0005372) |
| 0.0 | 1.4 | GO:0070035 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 0.2 | GO:0048019 | receptor antagonist activity(GO:0048019) |
| 0.0 | 0.5 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.0 | 2.0 | GO:0051020 | GTPase binding(GO:0051020) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 76.1 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 2.1 | 14.9 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 1.9 | 194.6 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 1.6 | 66.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 1.6 | 17.6 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 1.4 | 2.9 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 1.4 | 45.5 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 1.4 | 11.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 1.4 | 26.5 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 1.4 | 43.9 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 1.2 | 28.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 1.1 | 68.7 | PID BCR 5PATHWAY | BCR signaling pathway |
| 1.0 | 38.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.9 | 4.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.9 | 3.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.9 | 27.7 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.9 | 12.6 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.9 | 4.4 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.9 | 35.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.9 | 36.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.8 | 57.7 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.8 | 19.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.8 | 6.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.7 | 9.2 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.7 | 27.3 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.7 | 12.1 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.7 | 12.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.7 | 17.2 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.6 | 27.5 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.6 | 3.8 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.6 | 20.9 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.6 | 2.8 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.5 | 7.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.5 | 2.6 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.5 | 45.5 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.5 | 44.9 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.5 | 9.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.5 | 23.5 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.5 | 23.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.4 | 3.9 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.4 | 6.4 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.4 | 6.8 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.4 | 72.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.4 | 10.6 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.4 | 6.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.4 | 5.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.4 | 9.5 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.4 | 20.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.4 | 4.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.4 | 12.1 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.4 | 37.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.4 | 21.9 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.4 | 12.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.4 | 21.1 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.3 | 11.0 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.3 | 2.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.3 | 4.5 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.3 | 15.1 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.3 | 9.5 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.3 | 7.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.3 | 3.0 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.3 | 4.6 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.3 | 3.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.3 | 4.5 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.2 | 2.7 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 8.0 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.2 | 2.9 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.2 | 17.0 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.2 | 65.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 3.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.2 | 1.0 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.2 | 2.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.1 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 2.4 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 4.2 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 3.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.4 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 5.1 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 1.9 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 1.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 0.7 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 18.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.2 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.6 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.2 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 157.8 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 3.6 | 97.9 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 3.3 | 68.6 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 2.4 | 66.9 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 2.3 | 65.5 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 1.6 | 8.2 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 1.6 | 100.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 1.5 | 124.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 1.4 | 4.3 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 1.4 | 18.3 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 1.4 | 25.2 | REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
| 1.4 | 9.7 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 1.4 | 29.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 1.3 | 51.8 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 1.3 | 29.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 1.3 | 42.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 1.1 | 16.9 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 1.0 | 46.2 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 1.0 | 27.3 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.9 | 8.3 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.9 | 16.0 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.9 | 69.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.8 | 24.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.8 | 23.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.8 | 16.4 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.8 | 14.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.8 | 13.5 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.8 | 21.0 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.7 | 13.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.7 | 26.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.7 | 13.6 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.7 | 10.7 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.7 | 18.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.6 | 3.1 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.6 | 31.1 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.6 | 7.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.6 | 4.5 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.6 | 8.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.6 | 11.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.5 | 6.4 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.5 | 11.4 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.5 | 13.8 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.4 | 5.6 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.4 | 3.9 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.4 | 8.9 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.4 | 5.1 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.4 | 7.4 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.4 | 67.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.4 | 8.1 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.4 | 5.0 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.4 | 13.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.4 | 4.5 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.4 | 12.6 | REACTOME DAG AND IP3 SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.4 | 15.1 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.4 | 49.8 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.3 | 2.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.3 | 8.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.3 | 9.6 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.3 | 7.5 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.3 | 10.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.3 | 12.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.3 | 3.1 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.3 | 4.2 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.3 | 3.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.3 | 3.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.3 | 7.6 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.3 | 3.5 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.3 | 4.3 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.3 | 1.8 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 3.1 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.2 | 8.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.2 | 3.0 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.2 | 8.0 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.2 | 3.9 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.2 | 14.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 4.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.2 | 4.8 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.2 | 6.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 2.7 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.2 | 5.4 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.2 | 10.4 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.2 | 15.5 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.2 | 1.6 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 2.6 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 4.1 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 3.9 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.2 | 2.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 3.7 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.9 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.1 | 1.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 3.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.9 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 5.8 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 4.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 3.3 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 5.3 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.3 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.1 | 2.4 | REACTOME SIGNALING BY FGFR IN DISEASE | Genes involved in Signaling by FGFR in disease |
| 0.1 | 1.7 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 1.1 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.1 | 0.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 5.6 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 1.9 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 1.7 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 2.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.4 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.1 | 2.2 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 0.7 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 1.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 3.4 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 5.0 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.1 | 0.9 | REACTOME METABOLISM OF MRNA | Genes involved in Metabolism of mRNA |
| 0.0 | 4.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.6 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |
| 0.0 | 0.4 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 1.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |