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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for SMAD1

Z-value: 1.00

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Transcription factors associated with SMAD1

Gene Symbol Gene ID Gene Info
ENSG00000170365.5 SMAD family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD1hg19_v2_chr4_+_146402925_146402957-0.522.0e-16Click!

Activity profile of SMAD1 motif

Sorted Z-values of SMAD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106209368 116.24 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_33048483 99.78 ENST00000419277.1
major histocompatibility complex, class II, DP alpha 1
chr14_-_106111127 78.25 ENST00000390545.2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_106237742 67.27 ENST00000390551.2
immunoglobulin heavy constant gamma 3 (G3m marker)
chr21_-_46330545 66.19 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_106092403 65.38 ENST00000390543.2
immunoglobulin heavy constant gamma 4 (G4m marker)
chr6_+_33043703 62.62 ENST00000418931.2
ENST00000535465.1
major histocompatibility complex, class II, DP beta 1
chr6_+_33048222 58.98 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr16_+_222846 51.56 ENST00000251595.6
ENST00000397806.1
hemoglobin, alpha 2
chr19_+_39897453 48.41 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36 ring finger protein
chr11_-_5248294 45.37 ENST00000335295.4
hemoglobin, beta
chrX_-_107018969 45.03 ENST00000372383.4
TSC22 domain family, member 3
chr19_+_49838653 43.46 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr22_+_23264766 42.79 ENST00000390331.2
immunoglobulin lambda constant 7
chr22_+_23247030 42.28 ENST00000390324.2
immunoglobulin lambda joining 3
chr2_+_90077680 42.12 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_-_89310012 39.67 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr22_+_23241661 38.14 ENST00000390322.2
immunoglobulin lambda joining 2
chr18_+_74240610 37.06 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr22_+_23040274 36.85 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_23237555 35.00 ENST00000390321.2
immunoglobulin lambda constant 1 (Mcg marker)
chr16_-_55866997 34.79 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr6_+_31583761 34.67 ENST00000376049.4
allograft inflammatory factor 1
chrX_-_107019181 34.59 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22 domain family, member 3
chr2_+_90139056 33.54 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr22_-_19512893 33.29 ENST00000403084.1
ENST00000413119.2
claudin 5
chr9_+_139871948 32.43 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
prostaglandin D2 synthase 21kDa (brain)
chr19_+_1065922 32.38 ENST00000539243.2
histocompatibility (minor) HA-1
chr22_+_23243156 32.33 ENST00000390323.2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr17_+_38083977 31.28 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr22_-_45559642 31.17 ENST00000426282.2
CTA-217C2.1
chr6_+_32709119 30.99 ENST00000374940.3
major histocompatibility complex, class II, DQ alpha 2
chr1_-_31230650 29.30 ENST00000294507.3
lysosomal protein transmembrane 5
chr9_+_139874683 29.24 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr6_+_32605195 29.24 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr3_-_138763734 29.16 ENST00000413199.1
ENST00000502927.2
proline rich 23C
chr18_+_77439775 28.62 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr14_-_106054659 28.34 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr2_-_89292422 27.91 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_22707260 27.67 ENST00000390293.1
immunoglobulin lambda variable 5-48 (non-functional)
chr6_-_31550192 27.53 ENST00000429299.2
ENST00000446745.2
lymphotoxin beta (TNF superfamily, member 3)
chr11_+_121461097 26.84 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_-_51529849 26.42 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
kallikrein-related peptidase 11
chr19_-_54784353 26.13 ENST00000391746.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr2_-_89399845 25.97 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr22_+_23134974 25.89 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr19_-_17185848 25.85 ENST00000593360.1
HAUS augmin-like complex, subunit 8
chr22_-_27620603 25.84 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr17_-_29641084 25.74 ENST00000544462.1
ecotropic viral integration site 2B
chr19_+_55141948 25.72 ENST00000396332.4
ENST00000427581.2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr16_+_226658 25.65 ENST00000320868.5
ENST00000397797.1
hemoglobin, alpha 1
chr4_+_76439665 25.15 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chr16_+_66914264 25.13 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_-_31239846 24.74 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
major histocompatibility complex, class I, C
chr9_+_139873264 24.64 ENST00000446677.1
prostaglandin D2 synthase 21kDa (brain)
chr18_-_47813940 24.62 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC finger protein 1
chr19_+_42381173 24.53 ENST00000221972.3
CD79a molecule, immunoglobulin-associated alpha
chr3_-_39322728 24.52 ENST00000541347.1
ENST00000412814.1
chemokine (C-X3-C motif) receptor 1
chr19_-_16582815 23.94 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
epidermal growth factor receptor pathway substrate 15-like 1
chr22_+_23101182 23.68 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr19_+_52901094 23.63 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
zinc finger protein 528
chr22_+_23229960 23.51 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr19_-_6690723 23.49 ENST00000601008.1
complement component 3
chr22_+_23165153 23.45 ENST00000390317.2
immunoglobulin lambda variable 2-8
chr4_-_1166954 23.30 ENST00000514490.1
ENST00000431380.1
ENST00000503765.1
spondin 2, extracellular matrix protein
chr2_-_99224915 23.27 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr4_+_128554081 23.23 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr16_+_3115323 22.79 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
interleukin 32
chr6_-_74161977 22.62 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr11_-_2323290 22.58 ENST00000381153.3
chromosome 11 open reading frame 21
chr2_-_87017985 22.48 ENST00000352580.3
CD8a molecule
chr2_+_241564655 22.37 ENST00000407714.1
G protein-coupled receptor 35
chr11_+_1891380 22.35 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
lymphocyte-specific protein 1
chr3_+_156544057 22.23 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr9_-_97401782 22.16 ENST00000375326.4
fructose-1,6-bisphosphatase 1
chr14_-_106174960 21.92 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr22_+_23077065 21.88 ENST00000390310.2
immunoglobulin lambda variable 2-18
chr2_-_89278535 21.84 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr1_-_204380919 21.75 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr5_-_172198190 21.71 ENST00000239223.3
dual specificity phosphatase 1
chr11_+_2323349 21.47 ENST00000381121.3
tetraspanin 32
chr2_-_89513402 21.44 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr3_-_46506563 21.42 ENST00000231751.4
lactotransferrin
chr16_+_3115298 21.41 ENST00000325568.5
ENST00000534507.1
interleukin 32
chr19_-_51875894 21.38 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr19_+_42381337 21.37 ENST00000597454.1
ENST00000444740.2
CD79a molecule, immunoglobulin-associated alpha
chr13_-_30881621 21.31 ENST00000380615.3
katanin p60 subunit A-like 1
chr22_+_22681656 21.17 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr16_+_3115378 21.04 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
interleukin 32
chr16_+_30483962 20.87 ENST00000356798.6
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr19_+_1067271 20.86 ENST00000536472.1
ENST00000590214.1
histocompatibility (minor) HA-1
chr19_+_1077393 20.81 ENST00000590577.1
histocompatibility (minor) HA-1
chrX_+_70586140 20.79 ENST00000276072.3
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr1_+_152635854 20.75 ENST00000368784.1
late cornified envelope 2D
chr19_+_16435625 20.70 ENST00000248071.5
ENST00000592003.1
Kruppel-like factor 2
chr5_-_131826457 20.59 ENST00000437654.1
ENST00000245414.4
interferon regulatory factor 1
chr6_+_31582961 20.50 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr11_+_695614 20.47 ENST00000608174.1
ENST00000397512.3
transmembrane protein 80
chr17_-_29641104 20.35 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr7_-_150038704 20.33 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
retinoic acid receptor responder (tazarotene induced) 2
chr11_+_695787 20.16 ENST00000526170.1
ENST00000488769.1
transmembrane protein 80
chr15_+_89181974 20.03 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr4_-_681114 19.99 ENST00000503156.1
major facilitator superfamily domain containing 7
chr2_-_87018784 19.97 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr2_-_11272234 19.76 ENST00000590207.1
ENST00000417697.2
ENST00000396164.1
ENST00000536743.1
ENST00000544306.1
AC062028.1
chr17_-_80275417 19.71 ENST00000583376.1
ENST00000578509.1
ENST00000584284.1
ENST00000582480.1
CD7 molecule
chr3_+_183967409 19.52 ENST00000324557.4
ENST00000402825.3
endothelin converting enzyme 2
chr3_+_45071622 19.45 ENST00000428034.1
C-type lectin domain family 3, member B
chr4_-_1166623 19.42 ENST00000290902.5
spondin 2, extracellular matrix protein
chr15_+_75074410 19.33 ENST00000439220.2
c-src tyrosine kinase
chr19_-_12662240 19.30 ENST00000416136.1
ENST00000428311.1
zinc finger protein 564
ZNF709
chr17_-_40021656 19.10 ENST00000319121.3
kelch-like family member 11
chr2_-_89521942 19.07 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr16_+_30484021 18.99 ENST00000358164.5
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr12_+_6898638 18.99 ENST00000011653.4
CD4 molecule
chr10_+_38299546 18.84 ENST00000374618.3
ENST00000432900.2
ENST00000458705.2
ENST00000469037.2
zinc finger protein 33A
chr17_-_79269067 18.75 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr1_+_28206150 18.73 ENST00000456990.1
thymocyte selection associated family member 2
chr12_+_7055631 18.72 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr17_+_34431212 18.70 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr17_-_37844267 18.68 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
post-GPI attachment to proteins 3
chr2_-_89340242 18.67 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr11_-_66360548 18.63 ENST00000333861.3
coiled-coil domain containing 87
chr5_+_54398463 18.54 ENST00000274306.6
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr19_-_6481776 18.46 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENN/MADD domain containing 1C
chr2_+_89923550 18.46 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chrX_-_19002696 18.46 ENST00000379942.4
phosphorylase kinase, alpha 2 (liver)
chr13_+_25338290 18.38 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
ring finger protein 17
chr3_+_153839149 18.32 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr20_-_23066953 18.29 ENST00000246006.4
CD93 molecule
chr3_+_40566369 18.20 ENST00000403205.2
ENST00000310898.1
ENST00000339296.5
ENST00000431278.1
zinc finger protein 621
chr2_-_89442621 18.14 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr17_+_77681075 18.08 ENST00000397549.2
CTD-2116F7.1
chr1_+_153330322 17.97 ENST00000368738.3
S100 calcium binding protein A9
chr7_+_100136811 17.96 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr15_+_81589254 17.94 ENST00000394652.2
interleukin 16
chr2_+_89901292 17.92 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr11_-_18034701 17.91 ENST00000265965.5
secretion regulating guanine nucleotide exchange factor
chr19_+_45973120 17.87 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr2_-_89459813 17.86 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr11_+_1889880 17.83 ENST00000405957.2
lymphocyte-specific protein 1
chr1_-_27961720 17.83 ENST00000545953.1
ENST00000374005.3
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr19_-_51587502 17.82 ENST00000156499.2
ENST00000391802.1
kallikrein-related peptidase 14
chr21_-_46340770 17.74 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_169725231 17.74 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_67205538 17.68 ENST00000326294.3
protein tyrosine phosphatase, receptor type, C-associated protein
chr1_-_161600990 17.56 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr16_-_55867146 17.42 ENST00000422046.2
carboxylesterase 1
chr19_-_16582754 17.42 ENST00000602151.1
ENST00000597937.1
ENST00000535753.2
epidermal growth factor receptor pathway substrate 15-like 1
chr14_-_107083690 17.31 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr11_+_124492749 17.23 ENST00000531667.1
ENST00000441174.3
ENST00000375005.4
transforming growth factor beta regulator 1
chr19_+_859425 17.21 ENST00000327726.6
complement factor D (adipsin)
chr19_-_36231437 17.18 ENST00000591748.1
IGF-like family receptor 1
chr1_-_52831796 17.17 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
coiled-coil and C2 domain containing 1B
chr4_-_156875003 17.12 ENST00000433477.3
cathepsin O
chr17_-_62009621 17.12 ENST00000349817.2
ENST00000392795.3
CD79b molecule, immunoglobulin-associated beta
chr1_+_32739733 17.09 ENST00000333070.4
lymphocyte-specific protein tyrosine kinase
chr2_+_131113609 17.08 ENST00000347849.3
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr11_+_2421718 17.03 ENST00000380996.5
ENST00000333256.6
ENST00000380992.1
ENST00000437110.1
ENST00000435795.1
tumor suppressing subtransferable candidate 4
chr9_+_134378289 16.99 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
protein-O-mannosyltransferase 1
chr14_-_94854926 16.93 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr21_-_46340884 16.87 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_106322288 16.82 ENST00000390559.2
immunoglobulin heavy constant mu
chr1_+_16767167 16.76 ENST00000337132.5
NECAP endocytosis associated 2
chr16_-_30032610 16.72 ENST00000574405.1
double C2-like domains, alpha
chr14_-_106692191 16.69 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr6_-_159420780 16.67 ENST00000449822.1
radial spoke 3 homolog (Chlamydomonas)
chr2_-_128568721 16.63 ENST00000322313.4
ENST00000393006.1
ENST00000409658.3
ENST00000436787.1
WD repeat domain 33
chr2_+_90108504 16.62 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr2_+_89999259 16.62 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr17_-_62009702 16.60 ENST00000006750.3
CD79b molecule, immunoglobulin-associated beta
chr2_-_89266286 16.59 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_+_85921522 16.57 ENST00000409696.3
granulysin
chr17_-_62084241 16.49 ENST00000449662.2
intercellular adhesion molecule 2
chr19_-_36643329 16.48 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr19_-_36297632 16.46 ENST00000588266.2
proline dehydrogenase (oxidase) 2
chr9_-_97402413 16.42 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr7_+_73623717 16.35 ENST00000344995.5
ENST00000460943.1
linker for activation of T cells family, member 2
chrX_+_70586082 16.32 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr16_-_25122785 16.31 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
chr5_+_157170703 16.30 ENST00000286307.5
LSM11, U7 small nuclear RNA associated
chr14_-_81687197 16.26 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr2_-_89619904 16.20 ENST00000498574.1
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr11_+_2323236 16.19 ENST00000182290.4
tetraspanin 32
chr6_-_31324943 16.18 ENST00000412585.2
ENST00000434333.1
major histocompatibility complex, class I, B
chr17_-_80275466 16.18 ENST00000312648.3
CD7 molecule
chr17_-_71410794 16.17 ENST00000424778.1
sidekick cell adhesion molecule 2
chr6_+_29691198 16.11 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr7_+_26438187 16.10 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr19_+_45417921 16.06 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
apolipoprotein C-I
chr17_-_62097927 16.06 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
intercellular adhesion molecule 2
chr5_-_149492904 16.03 ENST00000286301.3
ENST00000511344.1
colony stimulating factor 1 receptor
chr19_+_15752088 16.03 ENST00000585846.1
cytochrome P450, family 4, subfamily F, polypeptide 3
chr1_-_38157877 16.02 ENST00000477060.1
ENST00000491981.1
ENST00000488137.1
chromosome 1 open reading frame 109
chr11_+_71927807 16.01 ENST00000298223.6
ENST00000454954.2
ENST00000541003.1
ENST00000539412.1
ENST00000536778.1
ENST00000535625.1
ENST00000321324.7
folate receptor 2 (fetal)
chr19_-_58326267 16.01 ENST00000391701.1
zinc finger protein 552
chr17_-_41465674 15.97 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
long intergenic non-protein coding RNA 910
chr19_+_50922187 15.95 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
Spi-B transcription factor (Spi-1/PU.1 related)
chr2_-_158345462 15.87 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr11_-_73694346 15.85 ENST00000310473.3
uncoupling protein 2 (mitochondrial, proton carrier)

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
17.0 68.1 GO:0030185 nitric oxide transport(GO:0030185)
16.5 49.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
15.9 47.8 GO:1900159 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
13.7 54.8 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
13.1 39.4 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
13.0 38.9 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
12.8 38.3 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
12.6 50.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
12.3 61.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
12.2 36.5 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
11.8 94.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
11.1 44.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
10.8 43.4 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
10.7 42.9 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
10.6 21.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
10.6 95.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
10.3 51.7 GO:0036369 transcription factor catabolic process(GO:0036369)
10.2 724.7 GO:0006910 phagocytosis, recognition(GO:0006910)
10.1 10.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
10.0 30.1 GO:0002818 intracellular defense response(GO:0002818)
9.5 28.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
9.4 9.4 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
9.2 9.2 GO:0035878 nail development(GO:0035878)
8.8 26.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
8.5 51.1 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
8.5 17.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
8.5 25.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
8.4 25.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
8.3 41.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
8.2 33.0 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
8.1 24.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
8.1 24.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
7.9 31.8 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
7.7 7.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
7.6 60.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
7.6 45.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
7.4 44.1 GO:0070560 protein secretion by platelet(GO:0070560)
7.3 43.8 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
7.2 43.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
7.2 21.5 GO:1905224 clathrin-coated pit assembly(GO:1905224)
7.1 21.4 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
7.1 141.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
7.0 7.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
6.9 20.6 GO:0061760 antifungal innate immune response(GO:0061760)
6.8 6.8 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
6.6 616.4 GO:0006958 complement activation, classical pathway(GO:0006958)
6.4 6.4 GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
6.4 19.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
6.3 19.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
6.3 50.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
6.3 31.3 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
6.0 18.0 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
5.9 5.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
5.8 17.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
5.7 17.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
5.7 17.1 GO:1903413 cellular response to bile acid(GO:1903413)
5.7 51.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
5.6 5.6 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
5.6 22.5 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
5.6 5.6 GO:0006000 fructose metabolic process(GO:0006000) fructose 1,6-bisphosphate metabolic process(GO:0030388)
5.6 27.8 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
5.4 21.7 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
5.4 5.4 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
5.4 21.5 GO:0015942 formate metabolic process(GO:0015942)
5.3 26.5 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
5.3 26.4 GO:0010813 neuropeptide catabolic process(GO:0010813)
5.2 10.4 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
5.2 15.6 GO:0071529 cementum mineralization(GO:0071529)
5.2 5.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
5.1 10.1 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
5.0 15.0 GO:1904316 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
4.9 24.6 GO:0002586 regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
4.9 29.3 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
4.9 14.6 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
4.8 4.8 GO:0007435 salivary gland morphogenesis(GO:0007435)
4.8 19.3 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
4.8 86.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
4.8 23.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
4.7 47.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.7 14.1 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
4.7 23.4 GO:0072144 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
4.7 4.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
4.6 64.2 GO:0015671 oxygen transport(GO:0015671)
4.6 13.7 GO:0060018 astrocyte fate commitment(GO:0060018)
4.5 4.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
4.5 13.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.3 52.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
4.3 12.9 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
4.3 17.2 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
4.3 29.8 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
4.2 16.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
4.2 12.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
4.1 20.6 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.1 8.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
4.1 4.1 GO:0043968 histone H2A acetylation(GO:0043968)
4.1 12.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
4.0 16.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.0 12.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
4.0 12.0 GO:1990502 dense core granule maturation(GO:1990502)
4.0 15.9 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
4.0 4.0 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
3.9 3.9 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
3.9 3.9 GO:0048807 female genitalia morphogenesis(GO:0048807)
3.9 55.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
3.9 11.6 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
3.9 19.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
3.8 19.0 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
3.8 11.3 GO:0043366 beta selection(GO:0043366)
3.7 11.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
3.7 22.4 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
3.7 11.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
3.7 18.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
3.6 21.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
3.6 25.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
3.6 25.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
3.6 10.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
3.6 21.3 GO:0051013 microtubule severing(GO:0051013)
3.5 17.7 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
3.5 10.6 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
3.5 7.0 GO:0006258 UDP-glucose catabolic process(GO:0006258)
3.5 10.5 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
3.5 10.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
3.5 13.9 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
3.5 3.5 GO:0046113 nucleobase catabolic process(GO:0046113)
3.5 6.9 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
3.4 13.7 GO:0048749 compound eye development(GO:0048749)
3.4 379.7 GO:0031295 T cell costimulation(GO:0031295)
3.3 6.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
3.3 19.9 GO:0030035 microspike assembly(GO:0030035)
3.3 16.6 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
3.3 19.8 GO:0018095 protein polyglutamylation(GO:0018095)
3.3 3.3 GO:0032606 regulation of type I interferon production(GO:0032479) type I interferon production(GO:0032606)
3.3 13.2 GO:0018094 protein polyglycylation(GO:0018094)
3.3 16.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.2 6.5 GO:0002088 lens development in camera-type eye(GO:0002088)
3.2 6.4 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
3.2 3.2 GO:0009896 positive regulation of catabolic process(GO:0009896)
3.2 25.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
3.2 3.2 GO:0060594 mammary gland specification(GO:0060594)
3.1 6.3 GO:0002384 hepatic immune response(GO:0002384)
3.1 9.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
3.1 6.3 GO:0001810 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
3.1 6.2 GO:0070543 response to linoleic acid(GO:0070543)
3.1 9.3 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
3.1 12.4 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
3.1 18.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
3.1 30.9 GO:1990403 embryonic brain development(GO:1990403)
3.1 9.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
3.1 6.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
3.1 30.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
3.1 9.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
3.0 9.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
3.0 18.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
3.0 18.2 GO:0015811 L-cystine transport(GO:0015811)
3.0 15.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
3.0 24.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
3.0 9.0 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
3.0 9.0 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.0 12.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
3.0 6.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
3.0 23.9 GO:0015705 iodide transport(GO:0015705)
3.0 23.8 GO:0006013 mannose metabolic process(GO:0006013)
3.0 5.9 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
3.0 11.8 GO:0032053 ciliary basal body organization(GO:0032053)
2.9 2.9 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
2.9 8.8 GO:1904430 negative regulation of t-circle formation(GO:1904430)
2.9 2.9 GO:0010755 regulation of plasminogen activation(GO:0010755)
2.9 11.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.9 14.6 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
2.9 5.8 GO:0098780 macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
2.9 8.7 GO:0070842 aggresome assembly(GO:0070842)
2.9 59.9 GO:0048730 epidermis morphogenesis(GO:0048730)
2.8 28.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
2.8 8.5 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
2.8 11.3 GO:0051866 general adaptation syndrome(GO:0051866)
2.8 11.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
2.8 11.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
2.8 19.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
2.8 2.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
2.8 8.3 GO:0010332 response to gamma radiation(GO:0010332)
2.7 2.7 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
2.7 5.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.7 5.4 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
2.7 8.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
2.7 10.8 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
2.7 8.1 GO:0007341 penetration of zona pellucida(GO:0007341)
2.7 5.4 GO:0071224 positive regulation of immature T cell proliferation(GO:0033091) cellular response to peptidoglycan(GO:0071224)
2.7 2.7 GO:0046487 glyoxylate metabolic process(GO:0046487)
2.7 10.7 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
2.7 5.4 GO:0002266 follicular dendritic cell activation(GO:0002266)
2.7 18.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
2.7 42.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
2.7 24.0 GO:0090197 positive regulation of chemokine secretion(GO:0090197)
2.7 8.0 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
2.7 13.3 GO:0071554 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
2.6 7.9 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
2.6 10.5 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
2.6 2.6 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
2.6 10.5 GO:0071279 cellular response to cobalt ion(GO:0071279)
2.6 2.6 GO:0035963 cellular response to interleukin-13(GO:0035963)
2.6 10.4 GO:0001825 blastocyst formation(GO:0001825)
2.6 20.9 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
2.6 2.6 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.6 10.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.6 53.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.6 15.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
2.5 5.0 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
2.5 10.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
2.5 65.4 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
2.5 20.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.5 15.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.5 125.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
2.5 10.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
2.5 15.0 GO:0042133 neurotransmitter metabolic process(GO:0042133)
2.5 7.5 GO:0010828 positive regulation of glucose transport(GO:0010828)
2.5 5.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
2.5 9.9 GO:0030279 negative regulation of ossification(GO:0030279)
2.5 2.5 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
2.5 2.5 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
2.5 4.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
2.5 14.7 GO:0061737 leukotriene signaling pathway(GO:0061737)
2.4 7.3 GO:0015680 intracellular copper ion transport(GO:0015680)
2.4 4.9 GO:0072237 metanephric proximal tubule development(GO:0072237)
2.4 79.9 GO:0006536 glutamate metabolic process(GO:0006536)
2.4 4.8 GO:0046110 xanthine metabolic process(GO:0046110)
2.4 7.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
2.4 4.8 GO:0002027 regulation of heart rate(GO:0002027)
2.4 4.8 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
2.4 23.9 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
2.4 12.0 GO:0046968 peptide antigen transport(GO:0046968)
2.4 4.8 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.4 7.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
2.4 19.1 GO:0006116 NADH oxidation(GO:0006116)
2.4 9.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
2.4 16.6 GO:0006102 isocitrate metabolic process(GO:0006102)
2.4 7.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
2.3 7.0 GO:0097359 UDP-glucosylation(GO:0097359)
2.3 2.3 GO:0032571 response to vitamin K(GO:0032571)
2.3 2.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
2.3 2.3 GO:0030317 sperm motility(GO:0030317)
2.3 7.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
2.3 9.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
2.3 16.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
2.3 6.9 GO:0045918 negative regulation of cytolysis(GO:0045918)
2.3 6.9 GO:2000870 regulation of progesterone secretion(GO:2000870)
2.3 9.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
2.3 16.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
2.3 6.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
2.3 6.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
2.3 9.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.3 9.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.3 6.8 GO:1904529 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
2.2 2.2 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
2.2 13.4 GO:0006477 protein sulfation(GO:0006477)
2.2 15.6 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
2.2 15.6 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
2.2 28.7 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
2.2 4.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826) negative regulation of T-helper 1 cell differentiation(GO:0045626)
2.2 6.6 GO:0008355 olfactory learning(GO:0008355)
2.2 6.6 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in vasculogenesis(GO:0035441)
2.2 8.8 GO:0009450 gamma-aminobutyric acid biosynthetic process(GO:0009449) gamma-aminobutyric acid catabolic process(GO:0009450) negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
2.2 11.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
2.2 2.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
2.2 4.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.2 13.0 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
2.2 10.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.2 43.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
2.1 6.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
2.1 10.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.1 6.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
2.1 10.7 GO:0050808 synapse organization(GO:0050808)
2.1 17.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
2.1 12.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
2.1 6.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
2.1 27.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
2.1 2.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
2.1 21.1 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
2.1 8.4 GO:0006929 substrate-dependent cell migration(GO:0006929)
2.1 21.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
2.1 6.3 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
2.1 18.8 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
2.1 6.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
2.1 4.1 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
2.1 6.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
2.1 35.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
2.1 2.1 GO:0009233 menaquinone metabolic process(GO:0009233)
2.0 6.1 GO:0001694 histamine biosynthetic process(GO:0001694)
2.0 16.4 GO:1903416 response to glycoside(GO:1903416)
2.0 12.3 GO:0001661 conditioned taste aversion(GO:0001661)
2.0 8.2 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
2.0 6.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
2.0 12.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.0 14.2 GO:0006772 thiamine metabolic process(GO:0006772)
2.0 4.0 GO:0008045 motor neuron axon guidance(GO:0008045)
2.0 16.1 GO:0007506 gonadal mesoderm development(GO:0007506)
2.0 4.0 GO:0019233 sensory perception of pain(GO:0019233)
2.0 16.0 GO:0019370 leukotriene biosynthetic process(GO:0019370)
2.0 4.0 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
2.0 12.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.0 12.0 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
2.0 9.9 GO:0006041 glucosamine metabolic process(GO:0006041)
2.0 59.1 GO:0045730 respiratory burst(GO:0045730)
2.0 19.7 GO:0019835 cytolysis(GO:0019835)
2.0 9.8 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
2.0 5.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
2.0 2.0 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
1.9 13.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.9 5.8 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.9 7.8 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.9 15.4 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.9 5.8 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
1.9 19.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.9 246.6 GO:0002377 immunoglobulin production(GO:0002377)
1.9 13.4 GO:0045007 depurination(GO:0045007)
1.9 1.9 GO:0035962 response to interleukin-13(GO:0035962)
1.9 20.9 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.9 3.8 GO:0035995 detection of muscle stretch(GO:0035995)
1.9 13.2 GO:0042426 choline catabolic process(GO:0042426)
1.9 7.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.9 7.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.9 26.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
1.9 18.5 GO:0010002 cardioblast differentiation(GO:0010002)
1.9 3.7 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.8 1.8 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
1.8 5.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
1.8 11.0 GO:0072719 cellular response to cisplatin(GO:0072719)
1.8 1.8 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
1.8 5.5 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.8 36.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.8 1.8 GO:0007635 chemosensory behavior(GO:0007635)
1.8 5.4 GO:0002584 negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
1.8 9.0 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
1.8 18.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
1.8 5.4 GO:0036090 cleavage furrow ingression(GO:0036090)
1.8 3.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.8 9.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.8 7.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
1.8 21.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.8 3.6 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.8 10.6 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
1.8 7.1 GO:0042335 cuticle development(GO:0042335)
1.7 28.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
1.7 5.2 GO:0032847 regulation of cellular pH reduction(GO:0032847)
1.7 6.9 GO:0018377 protein myristoylation(GO:0018377)
1.7 8.6 GO:0060017 parathyroid gland development(GO:0060017)
1.7 12.0 GO:0002281 macrophage activation involved in immune response(GO:0002281)
1.7 6.8 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
1.7 3.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
1.7 5.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.7 6.7 GO:0042713 sperm ejaculation(GO:0042713)
1.7 5.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.7 6.6 GO:0009822 alkaloid catabolic process(GO:0009822)
1.7 9.9 GO:0007258 JUN phosphorylation(GO:0007258)
1.6 4.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.6 9.9 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.6 4.9 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.6 21.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.6 13.1 GO:0070995 NADPH oxidation(GO:0070995)
1.6 9.8 GO:0015732 prostaglandin transport(GO:0015732)
1.6 6.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.6 6.5 GO:0051608 histamine transport(GO:0051608)
1.6 44.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
1.6 1.6 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
1.6 4.9 GO:1902809 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.6 4.9 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
1.6 9.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
1.6 4.8 GO:0043605 cellular amide catabolic process(GO:0043605)
1.6 11.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.6 1.6 GO:0071288 cellular response to mercury ion(GO:0071288)
1.6 9.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.6 12.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.6 3.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
1.6 9.4 GO:0042088 T-helper 1 type immune response(GO:0042088)
1.6 1.6 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.6 4.7 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
1.6 6.2 GO:1904179 positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of adipose tissue development(GO:1904179) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
1.6 7.8 GO:0035799 ureter maturation(GO:0035799)
1.5 4.6 GO:0019732 antifungal humoral response(GO:0019732)
1.5 6.2 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
1.5 3.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.5 7.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.5 4.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
1.5 4.6 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.5 15.3 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
1.5 3.0 GO:1904996 regulation of leukocyte adhesion to vascular endothelial cell(GO:1904994) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.5 6.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
1.5 1.5 GO:0070989 oxidative demethylation(GO:0070989)
1.5 4.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.5 30.2 GO:0097503 sialylation(GO:0097503)
1.5 22.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.5 4.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.5 6.0 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
1.5 13.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.5 7.5 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
1.5 53.8 GO:0018149 peptide cross-linking(GO:0018149)
1.5 9.0 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
1.5 4.5 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
1.5 4.4 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.5 5.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.5 16.2 GO:0030238 male sex determination(GO:0030238)
1.5 16.2 GO:0048251 elastic fiber assembly(GO:0048251)
1.5 35.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
1.5 8.8 GO:0071104 response to interleukin-9(GO:0071104)
1.5 19.1 GO:0014029 neural crest formation(GO:0014029)
1.5 61.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
1.5 4.4 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
1.5 2.9 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.4 2.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.4 4.3 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
1.4 1.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
1.4 7.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.4 4.3 GO:0009698 phenylpropanoid metabolic process(GO:0009698)
1.4 2.8 GO:0002371 dendritic cell cytokine production(GO:0002371)
1.4 4.3 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.4 9.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
1.4 5.6 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.4 5.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.4 8.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.4 13.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.4 15.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
1.4 5.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
1.4 6.9 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
1.4 8.3 GO:0071321 cellular response to cGMP(GO:0071321)
1.4 11.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
1.4 22.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
1.4 4.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
1.4 1.4 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
1.4 11.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.4 2.7 GO:0030850 prostate gland development(GO:0030850)
1.4 10.9 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.4 55.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.4 6.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.4 5.4 GO:0042414 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
1.4 6.8 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
1.3 13.5 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
1.3 1.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.3 2.7 GO:0002877 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
1.3 6.7 GO:0042359 vitamin D metabolic process(GO:0042359)
1.3 5.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
1.3 9.4 GO:0060534 trachea cartilage development(GO:0060534)
1.3 5.3 GO:0060197 cloacal septation(GO:0060197)
1.3 2.7 GO:1902534 single-organism membrane invagination(GO:1902534)
1.3 14.6 GO:0032364 oxygen homeostasis(GO:0032364)
1.3 2.6 GO:0071361 cellular response to ethanol(GO:0071361)
1.3 7.9 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
1.3 4.0 GO:0030324 lung development(GO:0030324)
1.3 2.6 GO:0061009 common bile duct development(GO:0061009)
1.3 2.6 GO:0018343 protein farnesylation(GO:0018343)
1.3 2.6 GO:0036269 swimming behavior(GO:0036269)
1.3 14.4 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
1.3 2.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
1.3 1.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
1.3 9.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.3 5.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.3 6.4 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
1.3 2.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
1.3 3.8 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
1.3 7.6 GO:0072672 neutrophil extravasation(GO:0072672)
1.3 3.8 GO:0072716 response to actinomycin D(GO:0072716)
1.3 2.5 GO:0032056 positive regulation of translation in response to stress(GO:0032056) positive regulation of translational initiation in response to stress(GO:0032058)
1.3 2.5 GO:0010193 response to ozone(GO:0010193)
1.3 2.5 GO:0001575 globoside metabolic process(GO:0001575)
1.3 2.5 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
1.3 1.3 GO:0033344 cholesterol efflux(GO:0033344)
1.2 5.0 GO:0030242 pexophagy(GO:0030242)
1.2 3.7 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.2 7.5 GO:0001554 luteolysis(GO:0001554)
1.2 6.2 GO:0003338 metanephros morphogenesis(GO:0003338)
1.2 6.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.2 5.0 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
1.2 8.7 GO:0042126 nitrate metabolic process(GO:0042126)
1.2 33.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
1.2 11.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.2 3.7 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
1.2 1.2 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
1.2 7.4 GO:2000052 regulation of non-canonical Wnt signaling pathway(GO:2000050) positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
1.2 55.4 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
1.2 6.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
1.2 9.8 GO:0042940 D-amino acid transport(GO:0042940)
1.2 6.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.2 13.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.2 3.7 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.2 9.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
1.2 7.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
1.2 6.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.2 4.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.2 9.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
1.2 7.2 GO:0042048 olfactory behavior(GO:0042048)
1.2 3.6 GO:0070781 response to biotin(GO:0070781)
1.2 2.4 GO:0000023 maltose metabolic process(GO:0000023)
1.2 22.7 GO:0001921 positive regulation of receptor recycling(GO:0001921)
1.2 10.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
1.2 2.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.2 4.7 GO:0035385 Roundabout signaling pathway(GO:0035385)
1.2 8.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
1.2 2.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.2 3.5 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
1.2 3.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
1.2 8.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.2 3.5 GO:0042631 cellular response to water deprivation(GO:0042631)
1.2 3.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.2 3.5 GO:0090675 intermicrovillar adhesion(GO:0090675)
1.2 7.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.2 15.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
1.2 2.3 GO:0048599 oocyte development(GO:0048599)
1.2 8.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.2 3.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
1.2 4.6 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
1.2 21.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
1.2 3.5 GO:0032092 positive regulation of protein binding(GO:0032092)
1.2 1.2 GO:0043615 astrocyte cell migration(GO:0043615)
1.1 2.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
1.1 3.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
1.1 8.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.1 1.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
1.1 6.8 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
1.1 1.1 GO:0060326 cell chemotaxis(GO:0060326)
1.1 5.7 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
1.1 3.4 GO:0071109 superior temporal gyrus development(GO:0071109)
1.1 3.4 GO:0042137 sequestering of neurotransmitter(GO:0042137)
1.1 3.4 GO:0048266 behavioral response to pain(GO:0048266)
1.1 5.7 GO:0023041 neuronal signal transduction(GO:0023041)
1.1 6.8 GO:0032466 negative regulation of cytokinesis(GO:0032466)
1.1 6.8 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.1 2.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.1 10.0 GO:0071313 cellular response to caffeine(GO:0071313)
1.1 1.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
1.1 4.4 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.1 1.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
1.1 2.2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
1.1 15.5 GO:1903510 mucopolysaccharide metabolic process(GO:1903510)
1.1 7.7 GO:0048820 hair follicle maturation(GO:0048820)
1.1 11.0 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
1.1 9.9 GO:0015747 urate transport(GO:0015747)
1.1 14.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
1.1 9.8 GO:0015074 DNA integration(GO:0015074)
1.1 3.3 GO:0032094 response to food(GO:0032094)
1.1 5.4 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.1 16.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
1.1 2.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.1 5.4 GO:0050765 negative regulation of phagocytosis(GO:0050765)
1.1 1.1 GO:0032425 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
1.1 1.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
1.1 6.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.1 2.2 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.1 13.0 GO:0032495 response to muramyl dipeptide(GO:0032495)
1.1 7.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
1.1 3.2 GO:0035634 response to stilbenoid(GO:0035634)
1.1 15.0 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
1.1 1.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
1.1 8.5 GO:0001573 ganglioside metabolic process(GO:0001573)
1.1 2.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.1 5.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.1 4.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
1.0 4.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
1.0 4.2 GO:0006857 oligopeptide transport(GO:0006857)
1.0 2.1 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.0 11.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
1.0 7.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
1.0 6.2 GO:0072677 eosinophil migration(GO:0072677)
1.0 3.1 GO:0097477 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
1.0 11.4 GO:0045351 type I interferon biosynthetic process(GO:0045351)
1.0 5.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
1.0 4.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.0 2.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.0 6.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
1.0 1.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.0 14.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.0 11.3 GO:0030322 stabilization of membrane potential(GO:0030322)
1.0 4.1 GO:0036035 osteoclast development(GO:0036035)
1.0 5.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 3.0 GO:0060348 bone development(GO:0060348)
1.0 12.1 GO:0042737 drug catabolic process(GO:0042737)
1.0 8.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.0 3.0 GO:0002024 diet induced thermogenesis(GO:0002024)
1.0 4.0 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
1.0 5.0 GO:0035063 nuclear speck organization(GO:0035063)
1.0 3.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
1.0 22.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.0 20.1 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
1.0 12.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
1.0 3.0 GO:0002933 lipid hydroxylation(GO:0002933) omega-hydroxylase P450 pathway(GO:0097267)
1.0 4.0 GO:0032526 response to retinoic acid(GO:0032526)
1.0 14.9 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
1.0 24.7 GO:0006068 ethanol catabolic process(GO:0006068)
1.0 7.9 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
1.0 3.9 GO:0090527 actin filament reorganization(GO:0090527)
1.0 4.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.0 2.9 GO:0038092 nodal signaling pathway(GO:0038092)
1.0 5.9 GO:0006021 inositol biosynthetic process(GO:0006021)
1.0 2.0 GO:1903412 response to bile acid(GO:1903412)
1.0 3.9 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
1.0 1.9 GO:0007320 insemination(GO:0007320)
1.0 12.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
1.0 3.9 GO:0015870 acetylcholine transport(GO:0015870)
1.0 5.8 GO:0001865 NK T cell differentiation(GO:0001865)
1.0 2.9 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
1.0 8.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
1.0 3.8 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.0 7.7 GO:0040019 positive regulation of embryonic development(GO:0040019)
1.0 2.9 GO:0051697 protein delipidation(GO:0051697)
1.0 2.9 GO:2000848 positive regulation of corticosteroid hormone secretion(GO:2000848) positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.9 3.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.9 2.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.9 1.9 GO:0023035 CD40 signaling pathway(GO:0023035)
0.9 2.8 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.9 10.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.9 2.8 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.9 3.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 4.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.9 1.8 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.9 12.9 GO:0060736 prostate gland growth(GO:0060736)
0.9 11.0 GO:0050807 regulation of synapse organization(GO:0050807)
0.9 52.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.9 3.7 GO:0042412 taurine biosynthetic process(GO:0042412)
0.9 9.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.9 4.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.9 2.7 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.9 1.8 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.9 11.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.9 4.5 GO:1904526 regulation of microtubule binding(GO:1904526)
0.9 2.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.9 7.2 GO:0010447 response to acidic pH(GO:0010447)
0.9 1.8 GO:0007538 primary sex determination(GO:0007538)
0.9 9.8 GO:0042116 macrophage activation(GO:0042116)
0.9 14.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.9 1.8 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.9 2.7 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.9 3.5 GO:0061107 seminal vesicle development(GO:0061107)
0.9 7.9 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.9 3.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.9 17.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.9 3.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.9 3.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.9 2.6 GO:0010927 cellular component assembly involved in morphogenesis(GO:0010927)
0.9 3.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.9 10.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.9 4.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.9 19.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.9 1.7 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.9 3.4 GO:0015793 glycerol transport(GO:0015793)
0.8 3.4 GO:0001757 somite specification(GO:0001757)
0.8 5.9 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.8 5.1 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.8 1.7 GO:0051106 base-excision repair, DNA ligation(GO:0006288) positive regulation of DNA ligation(GO:0051106)
0.8 1.7 GO:0030220 platelet formation(GO:0030220)
0.8 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.8 5.0 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.8 2.5 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.8 6.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.8 5.8 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.8 2.5 GO:0019530 taurine metabolic process(GO:0019530)
0.8 2.5 GO:0090208 positive regulation of triglyceride metabolic process(GO:0090208)
0.8 5.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.8 12.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.8 9.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.8 2.4 GO:0035148 tube formation(GO:0035148)
0.8 3.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.8 4.8 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.8 10.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.8 4.0 GO:0009642 response to light intensity(GO:0009642)
0.8 3.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.8 4.8 GO:1903800 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.8 4.8 GO:0006196 AMP catabolic process(GO:0006196)
0.8 4.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.8 16.7 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.8 11.9 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.8 3.2 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.8 10.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.8 0.8 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.8 1.6 GO:0009584 detection of visible light(GO:0009584)
0.8 2.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.8 2.3 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.8 4.6 GO:0006600 creatine metabolic process(GO:0006600)
0.8 1.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.8 2.3 GO:0090131 mesenchyme migration(GO:0090131)
0.8 3.1 GO:0051899 membrane depolarization(GO:0051899)
0.8 31.3 GO:0098760 response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.8 6.9 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.8 3.0 GO:1990266 neutrophil migration(GO:1990266)
0.8 0.8 GO:0042698 ovulation cycle(GO:0042698)
0.8 3.8 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.8 0.8 GO:0030432 peristalsis(GO:0030432)
0.7 3.0 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.7 2.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.7 2.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.7 1.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.7 1.5 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.7 3.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.7 1.5 GO:0015802 basic amino acid transport(GO:0015802) basic amino acid transmembrane transport(GO:1990822)
0.7 2.9 GO:0003335 corneocyte development(GO:0003335)
0.7 3.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.7 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.7 4.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.7 6.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.7 8.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.7 3.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.7 11.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.7 19.3 GO:0010107 potassium ion import(GO:0010107)
0.7 13.5 GO:0032456 endocytic recycling(GO:0032456)
0.7 5.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.7 13.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.7 3.5 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.7 33.1 GO:0006968 cellular defense response(GO:0006968)
0.7 33.7 GO:0050776 regulation of immune response(GO:0050776)
0.7 5.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.7 4.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.7 2.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.7 1.4 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.7 2.1 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.7 5.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.7 18.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.7 14.5 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.7 2.1 GO:0019323 pentose catabolic process(GO:0019323)
0.7 37.2 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.7 21.3 GO:0070206 protein trimerization(GO:0070206)
0.7 2.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.7 2.7 GO:0009583 detection of light stimulus(GO:0009583)
0.7 5.4 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.7 4.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 9.5 GO:0005513 detection of calcium ion(GO:0005513)
0.7 1.4 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635)
0.7 15.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.7 1.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.7 2.7 GO:0035082 axoneme assembly(GO:0035082)
0.7 4.0 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.7 2.7 GO:1905225 thyroid-stimulating hormone signaling pathway(GO:0038194) response to thyrotropin-releasing hormone(GO:1905225)
0.7 3.3 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.7 10.7 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.7 4.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.7 1.3 GO:0048867 stem cell fate determination(GO:0048867)
0.7 3.3 GO:0016101 diterpenoid metabolic process(GO:0016101)
0.7 11.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.7 3.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.7 2.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.7 3.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.7 1.3 GO:0032660 regulation of interleukin-17 production(GO:0032660) negative regulation of interleukin-17 production(GO:0032700)
0.7 5.9 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.7 2.0 GO:0046219 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.7 3.3 GO:0006828 manganese ion transport(GO:0006828)
0.7 3.9 GO:0097354 protein prenylation(GO:0018342) protein geranylgeranylation(GO:0018344) prenylation(GO:0097354)
0.7 7.2 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.6 3.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.6 3.2 GO:0006907 pinocytosis(GO:0006907)
0.6 5.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.6 10.3 GO:0050909 sensory perception of taste(GO:0050909)
0.6 1.9 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.6 9.6 GO:0097264 self proteolysis(GO:0097264)
0.6 1.9 GO:2000035 regulation of stem cell division(GO:2000035)
0.6 7.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 3.8 GO:0030091 protein repair(GO:0030091)
0.6 9.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.6 3.1 GO:0070307 lens fiber cell development(GO:0070307)
0.6 32.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.6 3.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.6 3.1 GO:0030070 insulin processing(GO:0030070)
0.6 1.9 GO:0014061 regulation of norepinephrine secretion(GO:0014061)
0.6 19.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.6 3.7 GO:0008343 adult feeding behavior(GO:0008343)
0.6 9.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.6 2.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 4.2 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.6 4.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.6 10.2 GO:0031018 endocrine pancreas development(GO:0031018)
0.6 2.4 GO:2000849 glucocorticoid secretion(GO:0035933) corticosterone secretion(GO:0035934) regulation of glucocorticoid secretion(GO:2000849) regulation of corticosterone secretion(GO:2000852)
0.6 2.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.6 3.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 2.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 1.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.6 6.5 GO:0007398 ectoderm development(GO:0007398)
0.6 1.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.6 1.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.6 3.5 GO:0046208 spermine catabolic process(GO:0046208)
0.6 0.6 GO:0070827 chromatin maintenance(GO:0070827)
0.6 4.6 GO:0051601 exocyst localization(GO:0051601)
0.6 7.5 GO:0060081 membrane hyperpolarization(GO:0060081)
0.6 8.6 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.6 8.6 GO:0097186 amelogenesis(GO:0097186)
0.6 2.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 2.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.6 1.7 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.6 5.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.6 2.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.6 2.3 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.6 6.8 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 1.1 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.6 1.7 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.6 3.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.6 9.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.6 2.8 GO:0046618 drug export(GO:0046618)
0.5 1.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.5 3.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 2.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.5 6.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.5 3.8 GO:0051904 melanosome localization(GO:0032400) establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402) pigment granule localization(GO:0051875) pigment granule transport(GO:0051904) establishment of pigment granule localization(GO:0051905)
0.5 1.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.5 1.6 GO:1990123 L-glutamate import(GO:0051938) amino acid import into cell(GO:1902837) L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
0.5 2.7 GO:0003014 renal system process(GO:0003014)
0.5 12.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.5 5.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 3.7 GO:0008218 bioluminescence(GO:0008218)
0.5 4.2 GO:0000050 urea cycle(GO:0000050)
0.5 4.2 GO:0060048 cardiac muscle contraction(GO:0060048)
0.5 1.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 1.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.5 1.1 GO:0046730 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.5 4.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.5 6.2 GO:0006906 vesicle fusion(GO:0006906)
0.5 2.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.5 4.7 GO:0042417 dopamine metabolic process(GO:0042417)
0.5 4.7 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.5 14.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.5 7.3 GO:0051255 spindle midzone assembly(GO:0051255)
0.5 1.6 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.5 7.3 GO:0051354 negative regulation of oxidoreductase activity(GO:0051354)
0.5 3.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.5 7.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.5 3.1 GO:0071493 cellular response to UV-B(GO:0071493)
0.5 2.0 GO:0097028 dendritic cell differentiation(GO:0097028)
0.5 3.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.5 10.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.5 1.0 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.5 18.7 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.5 3.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.5 13.4 GO:0006953 acute-phase response(GO:0006953)
0.5 2.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 9.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.5 3.4 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.5 11.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 1.5 GO:0072364 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.5 2.4 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.5 1.5 GO:0035564 regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) pronephros morphogenesis(GO:0072114)
0.5 3.4 GO:0002021 response to dietary excess(GO:0002021)
0.5 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 2.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.5 1.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.5 1.4 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.5 4.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.5 10.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.5 4.7 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 2.8 GO:0072538 T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539)
0.5 3.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.5 1.8 GO:0051026 chiasma assembly(GO:0051026)
0.5 2.7 GO:0045176 apical protein localization(GO:0045176)
0.5 1.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.5 4.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.5 4.1 GO:0060074 synapse maturation(GO:0060074)
0.5 9.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.5 2.7 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.5 5.4 GO:0021772 olfactory bulb development(GO:0021772)
0.4 5.8 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.4 22.0 GO:0042073 intraciliary transport(GO:0042073)
0.4 2.6 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.4 0.4 GO:0070640 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.4 3.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.4 0.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 3.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.4 3.0 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.4 0.9 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 2.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.4 3.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.4 5.5 GO:0044458 motile cilium assembly(GO:0044458)
0.4 1.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.4 2.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.4 1.3 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.4 8.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.4 1.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.4 2.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.4 2.0 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) regulation of glucose mediated signaling pathway(GO:1902659)
0.4 3.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.4 5.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.4 4.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.4 2.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.4 239.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.4 1.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 1.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.4 5.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.4 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.4 1.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.4 1.6 GO:0098930 axonal transport(GO:0098930)
0.4 3.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.4 2.7 GO:0009650 UV protection(GO:0009650)
0.4 1.1 GO:0016240 autophagosome docking(GO:0016240)
0.4 1.5 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.4 6.0 GO:0006853 carnitine shuttle(GO:0006853)
0.4 11.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.4 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 2.2 GO:0097484 dendrite extension(GO:0097484)
0.4 3.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.4 2.6 GO:0007625 grooming behavior(GO:0007625)
0.4 1.8 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.4 4.4 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.4 2.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.4 2.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 3.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 9.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.4 3.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.4 3.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.4 2.1 GO:0030916 otic vesicle formation(GO:0030916)
0.4 4.9 GO:0003229 ventricular cardiac muscle tissue development(GO:0003229)
0.3 4.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 24.5 GO:0007586 digestion(GO:0007586)
0.3 0.7 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.3 1.7 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.3 1.0 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.3 2.7 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.3 2.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.3 2.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.3 1.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 3.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.3 4.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 1.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3 2.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 0.6 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.3 1.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.3 1.6 GO:0010225 response to UV-C(GO:0010225)
0.3 2.2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 1.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 2.2 GO:0035640 exploration behavior(GO:0035640)
0.3 3.5 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.3 4.7 GO:0006004 fucose metabolic process(GO:0006004)
0.3 0.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.3 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.3 2.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 1.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 3.6 GO:0033198 response to ATP(GO:0033198)
0.3 0.3 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.3 6.3 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.3 3.6 GO:0006706 steroid catabolic process(GO:0006706)
0.3 2.7 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.3 3.2 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.3 1.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.3 1.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 2.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 2.0 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3 0.8 GO:0006434 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.3 0.8 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.3 1.9 GO:0007588 excretion(GO:0007588)
0.3 1.4 GO:0042462 eye photoreceptor cell development(GO:0042462) photoreceptor cell differentiation(GO:0046530)
0.3 8.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.3 7.4 GO:0035456 response to interferon-beta(GO:0035456)
0.3 4.1 GO:0007020 microtubule nucleation(GO:0007020)
0.3 2.7 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.3 2.4 GO:0044804 nucleophagy(GO:0044804)
0.3 0.3 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of terminal mannose on C branch(GO:0036510) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.3 1.1 GO:0018101 protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) histone citrullination(GO:0036414)
0.3 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 0.8 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 3.4 GO:0051639 actin filament network formation(GO:0051639)
0.3 1.3 GO:0072537 fibroblast activation(GO:0072537)
0.3 9.2 GO:0015698 inorganic anion transport(GO:0015698)
0.3 0.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 7.8 GO:0015701 bicarbonate transport(GO:0015701)
0.3 10.6 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.3 2.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 5.3 GO:0097352 autophagosome maturation(GO:0097352)
0.3 0.3 GO:0032536 regulation of cell projection size(GO:0032536)
0.2 5.9 GO:0032570 response to progesterone(GO:0032570)
0.2 2.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2 1.7 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 1.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 8.5 GO:0046849 bone remodeling(GO:0046849)
0.2 2.1 GO:0050832 defense response to fungus(GO:0050832)
0.2 5.3 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 1.6 GO:0031648 protein destabilization(GO:0031648)
0.2 0.7 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.2 1.8 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 0.2 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.2 8.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 11.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2 1.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.8 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.2 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.2 0.8 GO:0060033 anatomical structure regression(GO:0060033)
0.2 1.2 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.2 9.9 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.2 8.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 4.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 1.5 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.2 2.6 GO:0032147 activation of protein kinase activity(GO:0032147)
0.2 0.9 GO:1902884 positive regulation of response to oxidative stress(GO:1902884)
0.2 4.4 GO:0000272 polysaccharide catabolic process(GO:0000272) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 1.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.2 1.4 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.2 2.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 1.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.3 GO:0015816 glycine transport(GO:0015816)
0.2 3.2 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.2 0.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 0.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 2.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 0.6 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.2 2.0 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 0.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.4 GO:0045109 intermediate filament organization(GO:0045109)
0.1 3.7 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 1.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 1.8 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 1.1 GO:0042789 mRNA transcription(GO:0009299) mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 2.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.6 GO:0046622 positive regulation of organ growth(GO:0046622)
0.1 1.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.7 GO:0010744 positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.1 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 2.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 2.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.6 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 3.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 10.1 GO:0002250 adaptive immune response(GO:0002250)
0.1 0.9 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 1.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.8 GO:0007369 gastrulation(GO:0007369)
0.1 1.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 1.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 1.0 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.2 GO:0032528 microvillus organization(GO:0032528)
0.1 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 4.0 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
0.1 0.9 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.3 GO:0098711 iron ion import into cell(GO:0097459) iron ion import across plasma membrane(GO:0098711)
0.1 0.6 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 2.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.3 GO:2000615 histone H3-K9 acetylation(GO:0043970) regulation of histone H3-K9 acetylation(GO:2000615)
0.1 1.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.4 GO:0044108 cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1 0.5 GO:0098739 import across plasma membrane(GO:0098739)
0.1 0.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.1 GO:0055088 lipid homeostasis(GO:0055088)
0.1 1.5 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 0.6 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.3 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.3 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.2 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.6 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.0 GO:0060536 growth plate cartilage chondrocyte differentiation(GO:0003418) cartilage morphogenesis(GO:0060536)
0.0 1.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
23.4 140.7 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
22.8 68.4 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
17.8 71.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
16.0 337.0 GO:0042613 MHC class II protein complex(GO:0042613)
14.3 14.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
14.0 659.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
12.1 36.4 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
11.8 82.9 GO:0097013 phagocytic vesicle lumen(GO:0097013)
11.4 79.6 GO:0019814 immunoglobulin complex(GO:0019814)
9.5 104.9 GO:0042612 MHC class I protein complex(GO:0042612)
6.7 33.3 GO:0036398 TCR signalosome(GO:0036398)
6.3 31.6 GO:0001652 granular component(GO:0001652)
6.1 30.3 GO:0005602 complement component C1 complex(GO:0005602)
5.9 35.2 GO:1990584 cardiac Troponin complex(GO:1990584)
5.6 162.7 GO:0042101 T cell receptor complex(GO:0042101)
5.5 22.2 GO:1990745 EARP complex(GO:1990745)
5.4 21.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
5.3 26.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
5.2 15.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
4.7 94.7 GO:0001891 phagocytic cup(GO:0001891)
4.6 37.1 GO:0032010 phagolysosome(GO:0032010)
4.6 92.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
4.3 26.0 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
4.3 21.4 GO:0044530 supraspliceosomal complex(GO:0044530)
4.2 66.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
4.2 20.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
4.0 15.9 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
3.9 3.9 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
3.9 15.4 GO:0097224 sperm connecting piece(GO:0097224)
3.9 19.3 GO:0000801 central element(GO:0000801)
3.7 14.9 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
3.7 44.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
3.6 21.6 GO:0032444 activin responsive factor complex(GO:0032444)
3.4 17.0 GO:1990761 growth cone lamellipodium(GO:1990761)
3.3 13.1 GO:1990031 pinceau fiber(GO:1990031)
3.1 6.2 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
3.1 42.7 GO:0031089 platelet dense granule lumen(GO:0031089)
3.0 9.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
3.0 17.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
2.9 49.7 GO:0042627 chylomicron(GO:0042627)
2.9 11.5 GO:0097443 sorting endosome(GO:0097443)
2.9 34.4 GO:0097512 cardiac myofibril(GO:0097512)
2.6 76.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
2.6 28.9 GO:0042629 mast cell granule(GO:0042629)
2.6 10.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.5 42.5 GO:0030014 CCR4-NOT complex(GO:0030014)
2.4 28.8 GO:0005833 hemoglobin complex(GO:0005833)
2.4 7.1 GO:0070195 growth hormone receptor complex(GO:0070195)
2.4 23.5 GO:0097486 multivesicular body lumen(GO:0097486)
2.3 18.6 GO:0035976 AP1 complex(GO:0035976)
2.3 7.0 GO:0005588 collagen type V trimer(GO:0005588)
2.3 9.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.3 79.6 GO:0008305 integrin complex(GO:0008305)
2.2 17.8 GO:0045179 apical cortex(GO:0045179)
2.2 8.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
2.2 17.6 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
2.2 8.8 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
2.1 12.9 GO:0032280 symmetric synapse(GO:0032280)
2.1 27.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
2.1 91.0 GO:0001772 immunological synapse(GO:0001772)
2.1 317.8 GO:0072562 blood microparticle(GO:0072562)
2.1 18.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
2.0 8.0 GO:0045298 tubulin complex(GO:0045298)
2.0 5.9 GO:0036038 MKS complex(GO:0036038)
1.9 27.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.9 5.8 GO:0035189 Rb-E2F complex(GO:0035189)
1.9 24.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.9 3.7 GO:0005879 axonemal microtubule(GO:0005879)
1.8 5.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.8 10.8 GO:0030893 meiotic cohesin complex(GO:0030893)
1.8 3.6 GO:0032797 SMN complex(GO:0032797)
1.8 37.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.8 7.0 GO:0036128 CatSper complex(GO:0036128)
1.7 6.9 GO:0030314 junctional membrane complex(GO:0030314)
1.7 10.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.7 13.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.6 3.3 GO:0097454 Schwann cell microvillus(GO:0097454)
1.6 8.2 GO:0089701 U2AF(GO:0089701)
1.6 24.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.6 83.9 GO:0001533 cornified envelope(GO:0001533)
1.6 11.2 GO:0098845 postsynaptic endosome(GO:0098845)
1.6 4.8 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
1.6 6.4 GO:0097449 astrocyte projection(GO:0097449)
1.6 111.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
1.6 6.3 GO:0016514 SWI/SNF complex(GO:0016514)
1.6 6.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.6 4.7 GO:0031251 PAN complex(GO:0031251)
1.5 10.5 GO:0043203 axon hillock(GO:0043203)
1.5 17.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
1.5 25.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
1.5 10.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
1.5 73.1 GO:0016235 aggresome(GO:0016235)
1.5 5.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.4 2.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.4 5.6 GO:0014802 terminal cisterna(GO:0014802)
1.4 62.3 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
1.4 11.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.4 2.7 GO:0005927 muscle tendon junction(GO:0005927)
1.4 12.3 GO:0005827 polar microtubule(GO:0005827)
1.4 9.5 GO:0035253 ciliary rootlet(GO:0035253)
1.3 22.4 GO:0097225 sperm midpiece(GO:0097225)
1.3 13.2 GO:0097427 microtubule bundle(GO:0097427)
1.3 5.2 GO:0044194 cytolytic granule(GO:0044194)
1.3 11.8 GO:0016013 syntrophin complex(GO:0016013)
1.3 10.4 GO:0044294 dendritic growth cone(GO:0044294)
1.3 6.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.3 31.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.3 5.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
1.2 7.5 GO:0002177 manchette(GO:0002177)
1.2 33.3 GO:0051233 spindle midzone(GO:0051233)
1.2 4.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.2 3.5 GO:0071020 post-spliceosomal complex(GO:0071020)
1.2 8.2 GO:0032584 growth cone membrane(GO:0032584)
1.2 7.0 GO:0043218 compact myelin(GO:0043218)
1.2 20.8 GO:0031083 BLOC-1 complex(GO:0031083)
1.2 5.8 GO:0097386 glial cell projection(GO:0097386)
1.2 3.5 GO:0044423 virion(GO:0019012) virion part(GO:0044423)
1.1 5.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.1 10.2 GO:0034464 BBSome(GO:0034464)
1.1 2.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.1 7.8 GO:0097433 dense body(GO:0097433)
1.1 11.1 GO:0071953 elastic fiber(GO:0071953)
1.1 5.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.1 1.1 GO:0098984 neuron to neuron synapse(GO:0098984)
1.1 14.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
1.1 5.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.1 5.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
1.1 9.8 GO:0002080 acrosomal membrane(GO:0002080)
1.1 3.2 GO:0070695 FHF complex(GO:0070695)
1.0 5.2 GO:0071546 pi-body(GO:0071546)
1.0 11.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.0 6.1 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.0 9.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.0 14.0 GO:0005798 Golgi-associated vesicle(GO:0005798)
1.0 3.9 GO:0033263 CORVET complex(GO:0033263)
1.0 110.0 GO:0031225 anchored component of membrane(GO:0031225)
1.0 183.6 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
1.0 14.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.0 2.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.0 122.7 GO:0005796 Golgi lumen(GO:0005796)
0.9 99.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.9 6.6 GO:0042788 polysomal ribosome(GO:0042788)
0.9 3.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.9 3.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.9 13.8 GO:0042588 zymogen granule(GO:0042588)
0.9 17.5 GO:0034451 centriolar satellite(GO:0034451)
0.9 10.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.9 8.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.9 12.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.9 42.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.9 10.4 GO:0005642 annulate lamellae(GO:0005642)
0.9 3.4 GO:0097165 nuclear stress granule(GO:0097165)
0.9 12.0 GO:0005858 axonemal dynein complex(GO:0005858)
0.8 4.2 GO:0005577 fibrinogen complex(GO:0005577)
0.8 5.9 GO:0033391 chromatoid body(GO:0033391)
0.8 5.9 GO:0097361 CIA complex(GO:0097361)
0.8 3.3 GO:0031905 early endosome lumen(GO:0031905)
0.8 2.5 GO:0044447 axoneme part(GO:0044447)
0.8 5.8 GO:0000800 lateral element(GO:0000800)
0.8 3.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.8 4.9 GO:1990769 proximal neuron projection(GO:1990769)
0.8 2.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.8 4.9 GO:0060077 inhibitory synapse(GO:0060077)
0.8 21.2 GO:0035579 specific granule membrane(GO:0035579)
0.8 4.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.8 5.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.8 6.9 GO:0031010 ISWI-type complex(GO:0031010)
0.7 96.6 GO:0016605 PML body(GO:0016605)
0.7 3.0 GO:0043293 apoptosome(GO:0043293)
0.7 131.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.7 5.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.7 57.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.7 1.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.7 2.1 GO:0098536 deuterosome(GO:0098536)
0.7 25.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.7 48.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.7 1.4 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.7 6.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.7 4.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 2.0 GO:0060198 clathrin-sculpted vesicle(GO:0060198)
0.7 0.7 GO:0001740 Barr body(GO:0001740)
0.7 4.0 GO:0005883 neurofilament(GO:0005883)
0.7 2.7 GO:0000322 storage vacuole(GO:0000322)
0.7 4.7 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.7 46.1 GO:0005581 collagen trimer(GO:0005581)
0.7 2.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.6 1.3 GO:0033186 CAF-1 complex(GO:0033186)
0.6 2.6 GO:0005579 membrane attack complex(GO:0005579)
0.6 23.8 GO:0016592 mediator complex(GO:0016592)
0.6 7.7 GO:0005922 connexon complex(GO:0005922)
0.6 5.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.6 20.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 1.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.6 4.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.6 1.2 GO:0031906 late endosome lumen(GO:0031906)
0.6 4.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 14.0 GO:0034706 sodium channel complex(GO:0034706)
0.6 14.3 GO:0071565 nBAF complex(GO:0071565)
0.6 681.9 GO:0005615 extracellular space(GO:0005615)
0.6 4.0 GO:0001520 outer dense fiber(GO:0001520)
0.6 26.3 GO:0005902 microvillus(GO:0005902)
0.6 2.2 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.6 7.8 GO:0031904 endosome lumen(GO:0031904)
0.6 5.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.5 9.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 6.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.5 27.1 GO:0030118 clathrin coat(GO:0030118)
0.5 4.7 GO:0030897 HOPS complex(GO:0030897)
0.5 11.7 GO:0032590 dendrite membrane(GO:0032590)
0.5 2.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 1.5 GO:0032302 MutSbeta complex(GO:0032302)
0.5 10.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 1.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 2.4 GO:0035869 ciliary transition zone(GO:0035869)
0.5 16.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.5 8.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.5 8.9 GO:0034707 chloride channel complex(GO:0034707)
0.5 2.3 GO:0072687 meiotic spindle(GO:0072687)
0.5 3.2 GO:0072487 MSL complex(GO:0072487)
0.5 12.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.5 2.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 6.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 19.0 GO:0001726 ruffle(GO:0001726)
0.4 6.1 GO:0000346 transcription export complex(GO:0000346)
0.4 1.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.4 21.9 GO:0043235 receptor complex(GO:0043235)
0.4 1.6 GO:0031045 dense core granule(GO:0031045)
0.4 2.4 GO:0031527 filopodium membrane(GO:0031527)
0.4 3.2 GO:0030008 TRAPP complex(GO:0030008)
0.4 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.4 0.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.4 1.9 GO:0071797 LUBAC complex(GO:0071797)
0.4 2.2 GO:0044327 dendritic spine head(GO:0044327)
0.4 4.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 3.4 GO:0032589 neuron projection membrane(GO:0032589)
0.3 4.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 1.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 2.3 GO:0000242 pericentriolar material(GO:0000242)
0.3 6.2 GO:0031201 SNARE complex(GO:0031201)
0.3 11.4 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.3 1.2 GO:0042587 glycogen granule(GO:0042587)
0.3 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 15.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 14.4 GO:0043202 lysosomal lumen(GO:0043202)
0.3 1.9 GO:0000795 synaptonemal complex(GO:0000795)
0.3 17.5 GO:0042734 presynaptic membrane(GO:0042734)
0.3 3.5 GO:0014704 intercalated disc(GO:0014704)
0.3 4.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 17.4 GO:0005811 lipid particle(GO:0005811)
0.2 4.1 GO:0000812 Swr1 complex(GO:0000812)
0.2 2.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 3.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.6 GO:0031415 NatA complex(GO:0031415)
0.2 4.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.2 9.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 1.9 GO:0097542 ciliary tip(GO:0097542)
0.2 1.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 2.9 GO:0048786 presynaptic active zone(GO:0048786)
0.2 2.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 2.2 GO:0032433 filopodium tip(GO:0032433)
0.2 2.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 261.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.2 1.0 GO:0030061 mitochondrial crista(GO:0030061)
0.2 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 3.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 20.3 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.2 5.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 3.4 GO:0030175 filopodium(GO:0030175)
0.2 1.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.2 0.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 8.3 GO:0036064 ciliary basal body(GO:0036064)
0.2 1.8 GO:0097546 ciliary base(GO:0097546)
0.2 13.6 GO:0032587 ruffle membrane(GO:0032587)
0.2 0.6 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 0.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.9 GO:0042825 TAP complex(GO:0042825)
0.1 2.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.3 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.7 GO:0005901 caveola(GO:0005901)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 8.3 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.7 GO:0001741 XY body(GO:0001741)
0.1 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.1 GO:0071817 MMXD complex(GO:0071817)
0.1 4.3 GO:0030427 site of polarized growth(GO:0030427)
0.1 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 52.7 GO:0031224 intrinsic component of membrane(GO:0031224)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.4 GO:0097060 synaptic membrane(GO:0097060)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
21.7 86.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
21.0 147.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
16.5 49.6 GO:0008859 exoribonuclease II activity(GO:0008859)
14.4 202.3 GO:0032395 MHC class II receptor activity(GO:0032395)
14.3 14.3 GO:0001846 opsonin binding(GO:0001846)
13.2 727.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
12.8 38.3 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
12.6 50.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
11.3 22.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
11.1 88.9 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
10.9 54.5 GO:0004771 sterol esterase activity(GO:0004771)
10.8 53.8 GO:0047820 D-glutamate cyclase activity(GO:0047820)
9.1 36.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
8.9 115.9 GO:0005344 oxygen transporter activity(GO:0005344)
8.9 26.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
8.8 26.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
8.5 246.8 GO:0042605 peptide antigen binding(GO:0042605)
8.2 24.6 GO:0045322 unmethylated CpG binding(GO:0045322)
8.1 32.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
7.6 45.8 GO:0042610 CD8 receptor binding(GO:0042610)
7.5 67.4 GO:0043426 MRF binding(GO:0043426)
7.3 43.8 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
7.2 21.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
7.0 20.9 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
6.7 26.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
6.7 20.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
6.7 20.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
6.3 50.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
6.3 19.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
6.3 31.3 GO:0008420 CTD phosphatase activity(GO:0008420)
6.0 96.6 GO:0019864 IgG binding(GO:0019864)
6.0 18.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
6.0 18.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
5.9 17.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
5.6 28.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
5.6 5.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
5.5 22.0 GO:0042289 MHC class II protein binding(GO:0042289)
5.4 765.2 GO:0003823 antigen binding(GO:0003823)
5.2 20.9 GO:0061714 folic acid receptor activity(GO:0061714)
5.2 15.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
4.9 14.7 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
4.9 63.2 GO:0019957 C-C chemokine binding(GO:0019957)
4.9 34.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
4.9 14.6 GO:0061663 NEDD8 ligase activity(GO:0061663)
4.8 14.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
4.8 47.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
4.7 14.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
4.5 18.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
4.5 13.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
4.4 26.4 GO:0004522 ribonuclease A activity(GO:0004522)
4.3 69.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
4.3 21.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
4.3 12.9 GO:0004040 amidase activity(GO:0004040)
4.3 4.3 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
4.3 25.7 GO:0004882 androgen receptor activity(GO:0004882)
4.2 16.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
4.2 8.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
4.2 33.6 GO:0030172 troponin C binding(GO:0030172)
4.2 25.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
4.1 12.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
4.0 12.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
4.0 12.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
4.0 19.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
3.9 3.9 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
3.9 3.9 GO:0001855 complement component C4b binding(GO:0001855)
3.9 55.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
3.9 27.4 GO:0043208 glycosphingolipid binding(GO:0043208)
3.8 26.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.8 26.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
3.8 11.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
3.7 11.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
3.6 10.9 GO:0030350 iron-responsive element binding(GO:0030350)
3.6 18.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
3.6 10.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
3.6 10.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
3.6 21.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
3.5 10.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
3.5 10.5 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
3.5 13.8 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
3.4 6.8 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
3.4 10.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
3.4 13.4 GO:0008940 nitrate reductase activity(GO:0008940)
3.3 29.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
3.3 6.6 GO:0016936 galactoside binding(GO:0016936)
3.3 13.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
3.3 9.9 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
3.2 12.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.2 9.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
3.2 16.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
3.1 22.0 GO:0001515 opioid peptide activity(GO:0001515)
3.1 6.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
3.1 6.3 GO:1990254 keratin filament binding(GO:1990254)
3.1 12.3 GO:0016841 ammonia-lyase activity(GO:0016841)
3.1 9.2 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
3.0 12.2 GO:0019862 IgA binding(GO:0019862)
3.0 9.1 GO:0004802 transketolase activity(GO:0004802)
3.0 9.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
3.0 15.0 GO:0001594 trace-amine receptor activity(GO:0001594)
2.9 8.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
2.9 8.8 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
2.9 23.3 GO:0034711 inhibin binding(GO:0034711)
2.9 8.7 GO:0070628 proteasome binding(GO:0070628)
2.9 2.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
2.9 11.4 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.8 8.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
2.8 8.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.8 50.4 GO:0051787 misfolded protein binding(GO:0051787)
2.8 11.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.7 10.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
2.7 18.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
2.7 18.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.7 18.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.7 8.0 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
2.6 7.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.6 18.5 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
2.6 13.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.6 28.2 GO:0004875 complement receptor activity(GO:0004875)
2.6 17.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.5 20.3 GO:0070324 thyroid hormone binding(GO:0070324)
2.5 30.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.5 15.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
2.5 7.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
2.5 42.4 GO:0038191 neuropilin binding(GO:0038191)
2.5 5.0 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
2.5 5.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
2.5 7.4 GO:1990239 steroid hormone binding(GO:1990239)
2.5 7.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
2.5 24.5 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
2.4 4.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
2.4 4.8 GO:0070573 metallodipeptidase activity(GO:0070573)
2.4 12.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.4 9.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
2.4 4.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
2.4 23.9 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
2.4 4.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
2.4 26.3 GO:0008430 selenium binding(GO:0008430)
2.4 7.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.4 14.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
2.4 7.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
2.4 42.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.4 4.7 GO:0051373 FATZ binding(GO:0051373)
2.4 7.1 GO:0005148 prolactin receptor binding(GO:0005148)
2.3 9.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.3 7.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
2.3 9.3 GO:0019003 GDP binding(GO:0019003)
2.3 14.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.3 11.6 GO:0097643 amylin receptor activity(GO:0097643)
2.3 2.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
2.3 11.5 GO:0008131 primary amine oxidase activity(GO:0008131)
2.3 6.9 GO:0032090 Pyrin domain binding(GO:0032090)
2.3 59.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
2.3 6.8 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
2.3 25.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
2.3 9.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.2 20.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
2.2 11.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
2.2 13.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.2 9.0 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
2.2 33.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.2 11.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
2.2 13.3 GO:0003796 lysozyme activity(GO:0003796)
2.2 15.4 GO:0004126 cytidine deaminase activity(GO:0004126)
2.2 8.8 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
2.2 6.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.2 10.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
2.2 10.8 GO:0004995 tachykinin receptor activity(GO:0004995)
2.1 6.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
2.1 6.4 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
2.1 6.4 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
2.1 23.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.1 6.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
2.1 4.2 GO:0035473 lipase binding(GO:0035473)
2.1 18.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
2.1 2.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
2.1 18.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
2.1 8.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
2.1 18.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
2.0 8.2 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
2.0 6.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
2.0 8.1 GO:0031716 calcitonin receptor binding(GO:0031716)
2.0 10.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.0 6.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
2.0 11.9 GO:0042608 T cell receptor binding(GO:0042608)
2.0 5.9 GO:0048030 disaccharide binding(GO:0048030)
2.0 5.9 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
2.0 3.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
1.9 9.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.9 7.8 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
1.9 9.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.9 11.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.9 34.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.9 11.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
1.9 3.8 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
1.9 5.7 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.9 15.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
1.9 11.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
1.9 11.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.8 14.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
1.8 3.7 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978)
1.8 7.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
1.8 27.5 GO:0042609 CD4 receptor binding(GO:0042609)
1.8 18.3 GO:0031433 telethonin binding(GO:0031433)
1.8 10.9 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
1.8 21.8 GO:0045159 myosin II binding(GO:0045159)
1.8 1.8 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.8 19.9 GO:0051525 NFAT protein binding(GO:0051525)
1.8 12.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.8 14.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.8 3.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
1.8 37.2 GO:0050811 GABA receptor binding(GO:0050811)
1.8 26.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.8 22.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.7 10.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.7 15.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
1.7 10.4 GO:0045569 TRAIL binding(GO:0045569)
1.7 6.9 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.7 1.7 GO:0003909 DNA ligase activity(GO:0003909)
1.7 5.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.7 6.6 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
1.7 9.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.7 24.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.7 6.6 GO:0031685 adenosine receptor binding(GO:0031685)
1.6 4.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
1.6 8.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.6 1.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.6 4.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.6 19.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.6 12.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.6 19.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
1.6 38.7 GO:0071837 HMG box domain binding(GO:0071837)
1.6 16.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
1.6 4.8 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
1.6 4.8 GO:0005497 androgen binding(GO:0005497)
1.6 4.8 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.6 12.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.6 4.8 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
1.6 7.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.6 4.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.5 15.4 GO:0032027 myosin light chain binding(GO:0032027)
1.5 6.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.5 7.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.5 4.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
1.5 13.7 GO:0048495 Roundabout binding(GO:0048495)
1.5 6.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.5 333.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.5 12.1 GO:0004565 beta-galactosidase activity(GO:0004565)
1.5 7.6 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
1.5 6.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
1.5 15.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.5 18.0 GO:0034452 dynactin binding(GO:0034452)
1.5 10.4 GO:0050682 AF-2 domain binding(GO:0050682)
1.5 8.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.5 41.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.5 39.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.5 2.9 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.4 7.2 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
1.4 2.9 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
1.4 9.9 GO:0050294 steroid sulfotransferase activity(GO:0050294)
1.4 7.0 GO:0005000 vasopressin receptor activity(GO:0005000)
1.4 5.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
1.4 5.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.4 15.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
1.4 9.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.4 26.0 GO:0042288 MHC class I protein binding(GO:0042288)
1.4 13.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.4 2.7 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
1.4 5.4 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
1.4 5.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
1.4 5.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.3 6.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.3 2.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.3 21.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
1.3 8.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.3 4.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.3 23.8 GO:0070403 NAD+ binding(GO:0070403)
1.3 5.3 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.3 5.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
1.3 7.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.3 24.7 GO:0004623 phospholipase A2 activity(GO:0004623)
1.3 15.3 GO:0003680 AT DNA binding(GO:0003680)
1.3 11.4 GO:0043199 sulfate binding(GO:0043199)
1.3 15.2 GO:0070700 BMP receptor binding(GO:0070700)
1.3 36.6 GO:0042169 SH2 domain binding(GO:0042169)
1.3 3.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.3 97.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.3 16.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.3 8.8 GO:0000403 Y-form DNA binding(GO:0000403)
1.3 31.4 GO:0004383 guanylate cyclase activity(GO:0004383)
1.3 2.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.3 5.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
1.2 3.7 GO:0051379 alpha2-adrenergic receptor activity(GO:0004938) epinephrine binding(GO:0051379)
1.2 24.6 GO:0043495 protein anchor(GO:0043495)
1.2 3.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 3.7 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.2 9.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.2 7.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 6.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.2 7.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
1.2 3.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
1.2 8.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.2 6.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.2 13.2 GO:0031419 cobalamin binding(GO:0031419)
1.2 15.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.2 8.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.2 43.7 GO:0004180 carboxypeptidase activity(GO:0004180)
1.2 5.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.2 7.0 GO:0070569 uridylyltransferase activity(GO:0070569)
1.2 18.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
1.2 3.5 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
1.2 5.8 GO:0030275 LRR domain binding(GO:0030275)
1.2 19.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.2 6.9 GO:0004447 iodide peroxidase activity(GO:0004447)
1.1 3.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
1.1 11.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
1.1 11.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.1 5.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
1.1 2.2 GO:0036310 annealing helicase activity(GO:0036310)
1.1 103.3 GO:0019905 syntaxin binding(GO:0019905)
1.1 4.4 GO:0008431 vitamin E binding(GO:0008431)
1.1 5.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.1 4.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
1.1 3.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
1.1 56.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.1 4.2 GO:0070728 leucine binding(GO:0070728)
1.1 22.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
1.1 3.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.0 3.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 20.9 GO:0050780 dopamine receptor binding(GO:0050780)
1.0 3.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.0 7.2 GO:0008142 oxysterol binding(GO:0008142)
1.0 29.9 GO:0008009 chemokine activity(GO:0008009)
1.0 7.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
1.0 8.1 GO:0004000 adenosine deaminase activity(GO:0004000)
1.0 20.2 GO:0070300 phosphatidic acid binding(GO:0070300)
1.0 5.0 GO:0061665 SUMO ligase activity(GO:0061665)
1.0 5.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
1.0 4.0 GO:0030911 TPR domain binding(GO:0030911)
1.0 18.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.0 4.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.0 30.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.0 10.9 GO:0051434 BH3 domain binding(GO:0051434)
1.0 35.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
1.0 15.7 GO:0030284 estrogen receptor activity(GO:0030284)
1.0 3.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.0 12.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.0 1.9 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
1.0 10.6 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
1.0 5.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
1.0 4.8 GO:0050436 microfibril binding(GO:0050436)
1.0 26.0 GO:0001784 phosphotyrosine binding(GO:0001784)
1.0 5.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.9 2.8 GO:0004947 bradykinin receptor activity(GO:0004947)
0.9 9.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.9 13.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.9 5.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.9 8.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.9 4.6 GO:0004111 creatine kinase activity(GO:0004111)
0.9 4.6 GO:0019215 intermediate filament binding(GO:0019215)
0.9 1.8 GO:0071723 lipopeptide binding(GO:0071723)
0.9 9.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.9 2.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.9 2.7 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.9 4.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.9 3.6 GO:0017040 ceramidase activity(GO:0017040)
0.9 2.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.9 78.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.9 16.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.9 0.9 GO:0070888 E-box binding(GO:0070888)
0.9 11.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.9 27.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 4.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.9 13.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.9 38.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.9 6.1 GO:0048018 receptor agonist activity(GO:0048018)
0.9 6.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.9 36.6 GO:0070412 R-SMAD binding(GO:0070412)
0.8 3.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.8 1.7 GO:0043398 HLH domain binding(GO:0043398)
0.8 1.7 GO:0031386 protein tag(GO:0031386)
0.8 6.7 GO:0004707 MAP kinase activity(GO:0004707)
0.8 2.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.8 6.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.8 75.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8 3.3 GO:0070051 fibrinogen binding(GO:0070051)
0.8 9.0 GO:0015643 toxic substance binding(GO:0015643)
0.8 9.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.8 3.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.8 7.0 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.8 2.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.8 3.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.8 1.6 GO:0031404 chloride ion binding(GO:0031404)
0.8 2.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.8 0.8 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 22.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 8.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.8 2.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.8 16.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.8 3.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.7 3.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 5.9 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.7 1.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.7 2.9 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.7 8.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 20.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.7 11.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.7 2.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.7 31.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.7 2.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7 2.2 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.7 4.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 5.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.7 5.7 GO:0003682 chromatin binding(GO:0003682)
0.7 8.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 9.9 GO:0016594 glycine binding(GO:0016594)
0.7 4.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.7 4.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.7 2.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.7 3.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.7 1.4 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.7 3.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 35.0 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.7 1.4 GO:0010181 FMN binding(GO:0010181)
0.7 6.1 GO:0000150 recombinase activity(GO:0000150)
0.7 3.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 4.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.7 2.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.7 2.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.7 8.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 22.8 GO:0032451 demethylase activity(GO:0032451)
0.7 3.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.7 4.7 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.7 0.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.7 8.0 GO:0008199 ferric iron binding(GO:0008199)
0.7 11.3 GO:0005522 profilin binding(GO:0005522)
0.7 4.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7 11.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.7 3.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.7 5.9 GO:0004969 histamine receptor activity(GO:0004969)
0.7 3.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.6 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.6 35.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.6 5.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.6 2.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 3.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.6 14.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 1.9 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661) Rab geranylgeranyltransferase activity(GO:0004663)
0.6 3.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.6 1.9 GO:0008502 melatonin receptor activity(GO:0008502)
0.6 3.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.6 9.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 1.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 13.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.6 7.9 GO:0043178 alcohol binding(GO:0043178)
0.6 2.4 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6 1.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.6 2.4 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.6 1.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.6 3.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.6 1.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 5.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6 1.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.6 4.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.6 8.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.6 8.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.6 1.7 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.6 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.6 11.4 GO:0071949 FAD binding(GO:0071949)
0.6 5.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 7.3 GO:0019841 retinol binding(GO:0019841)
0.6 1.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.6 2.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.6 2.8 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.5 2.7 GO:0031013 troponin I binding(GO:0031013)
0.5 5.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.5 1.6 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.5 8.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.5 7.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.5 40.7 GO:0005179 hormone activity(GO:0005179)
0.5 2.7 GO:0017018 myosin phosphatase activity(GO:0017018)
0.5 2.1 GO:0004803 transposase activity(GO:0004803)
0.5 4.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.5 2.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.5 1.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.5 5.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.5 9.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.5 2.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.5 4.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 7.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.5 10.9 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.5 2.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 3.4 GO:0016015 morphogen activity(GO:0016015)
0.5 2.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.5 5.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.5 4.4 GO:0030276 clathrin binding(GO:0030276)
0.5 1.0 GO:0070052 collagen V binding(GO:0070052)
0.5 8.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 1.4 GO:0032810 sterol response element binding(GO:0032810)
0.5 2.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 6.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.5 207.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.5 1.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.5 7.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 1.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 1.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.5 10.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.5 5.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.5 8.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 6.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.4 0.4 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.4 0.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.4 4.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 2.2 GO:0046790 virion binding(GO:0046790)
0.4 3.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.4 10.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.4 1.3 GO:0005119 smoothened binding(GO:0005119)
0.4 3.9 GO:0008494 translation activator activity(GO:0008494)
0.4 20.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.4 7.2 GO:0005217 intracellular ligand-gated ion channel activity(GO:0005217)
0.4 5.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 1.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.4 4.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 1.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 6.5 GO:0005112 Notch binding(GO:0005112)
0.4 2.8 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 2.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.4 6.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 2.8 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.2 GO:0052659 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.4 5.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 4.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 1.2 GO:0055102 lipase inhibitor activity(GO:0055102)
0.4 7.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 0.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.4 4.6 GO:0000149 SNARE binding(GO:0000149)
0.4 1.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.4 10.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 37.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 14.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.4 10.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.4 1.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 1.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.4 6.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 1.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.4 2.2 GO:0070513 death domain binding(GO:0070513)
0.4 2.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 1.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 1.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 1.0 GO:0010851 cyclase regulator activity(GO:0010851)
0.3 4.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 5.2 GO:0043236 laminin binding(GO:0043236)
0.3 5.7 GO:0042805 actinin binding(GO:0042805)
0.3 22.5 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.3 1.0 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.3 2.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 13.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 7.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 22.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 6.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 79.6 GO:0005096 GTPase activator activity(GO:0005096)
0.3 3.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.3 4.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 3.6 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.4 GO:0038132 neuregulin binding(GO:0038132)
0.3 3.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 2.1 GO:0043274 phospholipase binding(GO:0043274)
0.3 5.2 GO:0043394 proteoglycan binding(GO:0043394)
0.3 2.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 23.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 245.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.3 4.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 1.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.3 1.1 GO:0016499 orexin receptor activity(GO:0016499)
0.3 0.8 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.3 8.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 2.9 GO:0004645 phosphorylase activity(GO:0004645)
0.3 5.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 11.9 GO:0043621 protein self-association(GO:0043621)
0.3 8.9 GO:0030332 cyclin binding(GO:0030332)
0.3 1.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 5.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3 4.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.3 7.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.2 GO:0099583 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 6.8 GO:0005262 calcium channel activity(GO:0005262)
0.2 0.7 GO:0005549 odorant binding(GO:0005549)
0.2 2.4 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.2 4.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 118.6 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.2 0.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 2.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 4.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 0.6 GO:0046332 SMAD binding(GO:0046332)
0.2 1.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 1.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 1.6 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.2 2.9 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.2 0.4 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.7 GO:0009374 biotin binding(GO:0009374)
0.2 0.5 GO:0070330 aromatase activity(GO:0070330)
0.2 0.5 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.2 5.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.2 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 0.7 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 3.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 4.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.1 GO:0048256 5'-flap endonuclease activity(GO:0017108) flap endonuclease activity(GO:0048256)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 6.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.1 5.1 GO:0005506 iron ion binding(GO:0005506)
0.1 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 3.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 3.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.2 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 274.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
4.3 108.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
3.8 3.8 PID S1P S1P2 PATHWAY S1P2 pathway
3.0 54.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
3.0 21.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
2.9 26.4 PID IL27 PATHWAY IL27-mediated signaling events
2.9 228.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
2.7 16.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
2.7 239.9 PID IL4 2PATHWAY IL4-mediated signaling events
2.4 36.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
2.3 129.8 PID BCR 5PATHWAY BCR signaling pathway
2.3 13.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
2.2 9.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
2.0 17.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.9 11.3 PID IL5 PATHWAY IL5-mediated signaling events
1.9 7.5 PID ALK1 PATHWAY ALK1 signaling events
1.8 46.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.8 59.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
1.8 19.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
1.6 6.3 ST STAT3 PATHWAY STAT3 Pathway
1.5 23.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.5 27.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
1.5 58.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.5 31.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.5 7.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
1.5 50.6 ST GAQ PATHWAY G alpha q Pathway
1.4 21.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.4 14.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
1.3 37.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
1.3 72.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.3 73.9 PID IL12 2PATHWAY IL12-mediated signaling events
1.3 12.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
1.3 3.8 PID IL3 PATHWAY IL3-mediated signaling events
1.2 24.3 PID S1P S1P3 PATHWAY S1P3 pathway
1.2 3.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
1.2 10.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
1.1 11.4 PID EPO PATHWAY EPO signaling pathway
1.1 7.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.1 14.0 PID EPHA FWDPATHWAY EPHA forward signaling
1.1 8.5 PID TNF PATHWAY TNF receptor signaling pathway
1.1 183.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.1 28.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
1.0 16.8 ST GA13 PATHWAY G alpha 13 Pathway
1.0 15.6 PID IFNG PATHWAY IFN-gamma pathway
1.0 11.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.0 62.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.0 18.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.9 26.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.9 10.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.9 31.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.9 6.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.8 22.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.8 201.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.8 27.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.8 7.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.8 38.6 PID FGF PATHWAY FGF signaling pathway
0.8 1.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.8 14.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.7 5.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7 13.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.7 38.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.6 1.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6 17.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 9.1 PID RAS PATHWAY Regulation of Ras family activation
0.6 6.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.5 14.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.5 7.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 2.7 PID IL23 PATHWAY IL23-mediated signaling events
0.5 10.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.5 32.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.5 9.5 PID ALK2 PATHWAY ALK2 signaling events
0.5 21.8 NABA COLLAGENS Genes encoding collagen proteins
0.5 14.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.5 5.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.5 28.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 7.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.4 2.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 11.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.4 13.1 PID ARF6 PATHWAY Arf6 signaling events
0.4 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.4 18.5 PID LKB1 PATHWAY LKB1 signaling events
0.4 5.5 ST ADRENERGIC Adrenergic Pathway
0.4 9.0 PID IL1 PATHWAY IL1-mediated signaling events
0.3 7.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 15.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 9.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 1.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 29.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 32.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 4.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 15.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 10.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 1.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 2.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 5.9 PID AP1 PATHWAY AP-1 transcription factor network
0.2 8.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 4.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 42.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 0.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.9 PID ATM PATHWAY ATM pathway
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 385.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
10.2 102.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
9.1 9.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
8.3 74.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
5.7 459.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
4.1 77.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
3.3 3.3 REACTOME TRIF MEDIATED TLR3 SIGNALING Genes involved in TRIF mediated TLR3 signaling
3.1 12.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
3.0 48.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
2.8 14.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
2.7 34.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.7 29.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
2.7 39.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
2.5 2.5 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
2.5 4.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
2.3 73.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
2.1 29.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
2.0 16.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
2.0 83.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.9 11.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.9 121.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
1.9 111.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.8 47.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
1.8 32.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
1.8 61.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
1.7 34.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.7 33.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.6 24.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.6 3.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
1.6 8.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
1.6 49.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.5 46.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.5 46.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.5 81.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
1.5 1.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
1.5 17.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.5 27.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.4 21.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.4 23.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.4 8.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
1.3 28.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
1.3 25.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
1.3 30.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.3 52.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.3 13.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.2 7.5 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
1.2 23.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
1.2 38.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.2 8.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.2 14.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.2 57.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.1 40.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.1 5.7 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
1.1 438.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
1.1 6.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.1 7.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
1.1 26.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.1 56.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
1.1 13.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
1.0 6.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.0 179.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
1.0 30.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
1.0 20.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
1.0 13.8 REACTOME DEFENSINS Genes involved in Defensins
1.0 6.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.9 8.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.9 17.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.9 8.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 17.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.9 21.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.9 9.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.9 2.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.8 3.4 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.8 11.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.8 6.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.8 6.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.8 5.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.8 26.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.8 105.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.8 19.8 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.8 29.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.7 14.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.7 15.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 12.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.7 22.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.7 26.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.7 2.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.6 7.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.6 11.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.6 9.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.6 10.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.6 12.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.6 12.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 6.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.6 13.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 3.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.6 7.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.6 5.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.5 38.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 8.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 7.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.5 16.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 6.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 13.6 REACTOME SIGNALING BY FGFR MUTANTS Genes involved in Signaling by FGFR mutants
0.5 2.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 35.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 10.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.4 9.4 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.4 5.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 17.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 2.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 4.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 1.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.4 1.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.4 5.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 13.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 8.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 13.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.3 4.0 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.3 37.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 2.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.3 2.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.3 6.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 12.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 21.3 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.3 5.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 5.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 2.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 3.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 2.4 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.3 17.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.3 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 7.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 10.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 1.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.2 3.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 4.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2 6.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.2 9.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 9.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 1.3 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.2 2.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 10.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 2.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 6.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 8.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 3.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 4.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis