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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for SOX9

Z-value: 0.78

Motif logo

Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
ENSG00000125398.5 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg19_v2_chr17_+_70117153_701171740.321.3e-06Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153643442 28.27 ENST00000368681.1
ENST00000361891.4
interleukin enhancer binding factor 2
chr17_-_73149921 28.27 ENST00000481647.1
ENST00000470924.1
hematological and neurological expressed 1
chr1_-_26232951 22.97 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr7_+_77167376 21.95 ENST00000435495.2
protein tyrosine phosphatase, non-receptor type 12
chr12_+_49621658 20.07 ENST00000541364.1
tubulin, alpha 1c
chr2_-_61765315 19.38 ENST00000406957.1
ENST00000401558.2
exportin 1 (CRM1 homolog, yeast)
chr6_-_128841503 19.14 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
protein tyrosine phosphatase, receptor type, K
chr9_+_80912059 18.30 ENST00000347159.2
ENST00000376588.3
phosphoserine aminotransferase 1
chr8_-_101965559 17.93 ENST00000353245.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_+_30687978 16.74 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr16_+_89989687 16.37 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr1_-_26232522 15.69 ENST00000399728.1
stathmin 1
chr12_+_69979113 15.30 ENST00000299300.6
chaperonin containing TCP1, subunit 2 (beta)
chr15_+_52311398 15.03 ENST00000261845.5
mitogen-activated protein kinase 6
chr12_+_69979210 14.91 ENST00000544368.2
chaperonin containing TCP1, subunit 2 (beta)
chr1_-_26233423 14.89 ENST00000357865.2
stathmin 1
chr5_+_159848807 14.79 ENST00000352433.5
pituitary tumor-transforming 1
chr6_+_114178512 14.16 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr3_-_149688502 13.82 ENST00000481767.1
ENST00000475518.1
profilin 2
chr12_+_69979446 13.79 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)
chr1_+_10459111 13.75 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
phosphogluconate dehydrogenase
chr3_-_149688896 13.53 ENST00000239940.7
profilin 2
chr2_-_151344172 13.32 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr1_-_113247543 12.90 ENST00000414971.1
ENST00000534717.1
ras homolog family member C
chr11_-_46867780 12.64 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
cytoskeleton associated protein 5
chr1_-_19426149 12.41 ENST00000429347.2
ubiquitin protein ligase E3 component n-recognin 4
chr5_+_159848854 12.14 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
pituitary tumor-transforming 1
chr7_+_12727250 11.80 ENST00000404894.1
ADP-ribosylation factor-like 4A
chr3_-_149688655 11.27 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr8_+_98656336 11.27 ENST00000336273.3
metadherin
chr19_+_16187816 11.25 ENST00000588410.1
tropomyosin 4
chr16_+_3068393 11.22 ENST00000573001.1
tumor necrosis factor receptor superfamily, member 12A
chr5_+_74632993 11.14 ENST00000287936.4
3-hydroxy-3-methylglutaryl-CoA reductase
chr2_+_102314161 11.13 ENST00000425019.1
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_55277436 11.06 ENST00000354474.6
reticulon 4
chr12_-_49582978 11.00 ENST00000301071.7
tubulin, alpha 1a
chr12_-_49582593 10.98 ENST00000295766.5
tubulin, alpha 1a
chr2_-_55276320 10.95 ENST00000357376.3
reticulon 4
chr2_-_55277692 10.80 ENST00000394611.2
reticulon 4
chr18_+_3449821 10.71 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr2_-_55277512 10.57 ENST00000402434.2
reticulon 4
chrX_+_48380205 10.57 ENST00000446158.1
ENST00000414061.1
emopamil binding protein (sterol isomerase)
chr2_+_10262857 10.55 ENST00000304567.5
ribonucleotide reductase M2
chr1_+_10271674 10.43 ENST00000377086.1
kinesin family member 1B
chr2_-_200323414 10.39 ENST00000443023.1
SATB homeobox 2
chr5_+_74633036 10.04 ENST00000343975.5
3-hydroxy-3-methylglutaryl-CoA reductase
chr4_+_41614909 10.00 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr2_-_55277654 9.86 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
reticulon 4
chr11_-_102323489 9.83 ENST00000361236.3
transmembrane protein 123
chr10_+_70748487 9.82 ENST00000361983.4
KIAA1279
chr6_-_53213780 9.81 ENST00000304434.6
ENST00000370918.4
ELOVL fatty acid elongase 5
chr5_-_146833485 9.75 ENST00000398514.3
dihydropyrimidinase-like 3
chr2_+_74425689 9.67 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr1_-_197115818 9.51 ENST00000367409.4
ENST00000294732.7
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr12_+_69633372 9.42 ENST00000456847.3
ENST00000266679.8
cleavage and polyadenylation specific factor 6, 68kDa
chr10_+_102106829 9.42 ENST00000370355.2
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_+_165797024 9.40 ENST00000372212.4
uridine-cytidine kinase 2
chr11_+_63953691 9.14 ENST00000543847.1
stress-induced-phosphoprotein 1
chr14_+_52456327 9.05 ENST00000556760.1
chromosome 14 open reading frame 166
chr6_-_79944336 9.02 ENST00000344726.5
ENST00000275036.7
high mobility group nucleosomal binding domain 3
chr7_+_134464414 8.94 ENST00000361901.2
caldesmon 1
chr1_+_155293702 8.86 ENST00000368347.4
RUN and SH3 domain containing 1
chr17_+_26646175 8.86 ENST00000583381.1
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr11_+_60691924 8.85 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
transmembrane protein 132A
chr16_-_19533404 8.75 ENST00000353258.3
glycerophosphodiester phosphodiesterase 1
chr12_-_49075941 8.65 ENST00000553086.1
ENST00000548304.1
KAT8 regulatory NSL complex subunit 2
chr7_+_129710350 8.62 ENST00000335420.5
ENST00000463413.1
kelch domain containing 10
chr10_-_104953009 8.59 ENST00000470299.1
ENST00000343289.5
5'-nucleotidase, cytosolic II
chr2_-_37899323 8.59 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr8_-_80993010 8.46 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr1_-_155880672 8.42 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr4_+_41614720 8.28 ENST00000509277.1
LIM and calponin homology domains 1
chr11_+_34073269 8.21 ENST00000389645.3
cell cycle associated protein 1
chr14_+_52456193 8.13 ENST00000261700.3
chromosome 14 open reading frame 166
chr17_+_35851570 7.93 ENST00000394386.1
dual specificity phosphatase 14
chr11_-_102323740 7.90 ENST00000398136.2
transmembrane protein 123
chr1_-_246580705 7.89 ENST00000541742.1
SET and MYND domain containing 3
chr2_-_175869936 7.85 ENST00000409900.3
chimerin 1
chr5_-_16936340 7.76 ENST00000507288.1
ENST00000513610.1
myosin X
chr15_-_64673630 7.65 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr10_+_6244829 7.60 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr17_-_73505961 7.60 ENST00000433559.2
CASK interacting protein 2
chr8_-_101965146 7.56 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr20_-_45984401 7.52 ENST00000311275.7
zinc finger, MYND-type containing 8
chr10_+_94050913 7.40 ENST00000358935.2
membrane-associated ring finger (C3HC4) 5
chr1_+_155294264 7.38 ENST00000368349.4
RUN and SH3 domain containing 1
chr11_+_34073195 7.31 ENST00000341394.4
cell cycle associated protein 1
chr17_-_39684550 7.24 ENST00000455635.1
ENST00000361566.3
keratin 19
chr7_+_128379346 7.24 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
calumenin
chr1_+_155294342 7.24 ENST00000292254.4
RUN and SH3 domain containing 1
chr12_-_49076002 7.22 ENST00000357861.3
ENST00000550347.1
ENST00000420613.2
ENST00000550931.1
ENST00000550870.1
KAT8 regulatory NSL complex subunit 2
chr1_+_50571949 7.15 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr17_-_49124230 7.05 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr18_+_3451646 7.03 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGFB-induced factor homeobox 1
chr1_+_33116765 7.03 ENST00000544435.1
ENST00000373485.1
ENST00000458695.2
ENST00000490500.1
ENST00000445722.2
retinoblastoma binding protein 4
chr17_+_26646121 7.00 ENST00000226230.6
transmembrane protein 97
chr7_+_16685756 6.95 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr15_+_41624892 6.92 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
nucleolar and spindle associated protein 1
chr10_-_13390270 6.90 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
selenophosphate synthetase 1
chr7_-_16685422 6.85 ENST00000306999.2
ankyrin repeat and MYND domain containing 2
chr7_+_134464376 6.84 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr6_+_119215308 6.74 ENST00000229595.5
anti-silencing function 1A histone chaperone
chr7_-_131241361 6.74 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
podocalyxin-like
chr12_+_69633407 6.73 ENST00000551516.1
cleavage and polyadenylation specific factor 6, 68kDa
chr14_+_102276209 6.69 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr1_-_243418344 6.59 ENST00000366542.1
centrosomal protein 170kDa
chr7_+_128379449 6.42 ENST00000479257.1
calumenin
chr13_+_53029564 6.41 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
cytoskeleton associated protein 2
chr8_+_98656693 6.35 ENST00000519934.1
metadherin
chr10_-_129924611 6.18 ENST00000368654.3
marker of proliferation Ki-67
chr3_-_182698381 6.09 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr1_-_115259337 6.01 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr3_-_57583052 5.94 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr17_+_33914460 5.93 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr1_+_33116743 5.89 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr1_-_243418621 5.86 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr7_-_99699538 5.77 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr1_-_225840747 5.75 ENST00000366843.2
ENST00000366844.3
enabled homolog (Drosophila)
chr22_+_19419425 5.73 ENST00000333130.3
mitochondrial ribosomal protein L40
chr9_+_108463234 5.73 ENST00000374688.1
transmembrane protein 38B
chr1_-_32801825 5.70 ENST00000329421.7
MARCKS-like 1
chrX_-_15872914 5.65 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
adaptor-related protein complex 1, sigma 2 subunit
chrX_-_20159934 5.58 ENST00000379593.1
ENST00000379607.5
eukaryotic translation initiation factor 1A, X-linked
chr19_+_24009879 5.56 ENST00000354585.4
ribosomal protein SA pseudogene 58
chrX_-_135962876 5.56 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr1_+_93913713 5.50 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chrX_-_16888448 5.46 ENST00000468092.1
ENST00000404022.1
ENST00000380087.2
retinoblastoma binding protein 7
chr2_-_86422523 5.45 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
inner membrane protein, mitochondrial
chr13_-_31040060 5.42 ENST00000326004.4
ENST00000341423.5
high mobility group box 1
chr11_+_63953587 5.41 ENST00000305218.4
ENST00000538945.1
stress-induced-phosphoprotein 1
chr8_+_26435359 5.33 ENST00000311151.5
dihydropyrimidinase-like 2
chr17_+_33914276 5.32 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr1_+_68150744 5.32 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr7_+_5632436 5.31 ENST00000340250.6
ENST00000382361.3
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_21503337 5.28 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_146833222 5.26 ENST00000534907.1
dihydropyrimidinase-like 3
chr15_-_41624685 5.17 ENST00000560640.1
ENST00000220514.3
Opa interacting protein 5
chr12_+_54378923 5.15 ENST00000303460.4
homeobox C10
chr17_-_40306934 5.14 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
Uncharacterized protein
RAB5C, member RAS oncogene family
chr1_+_150039369 5.13 ENST00000369130.3
ENST00000369128.5
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr17_+_75372165 5.12 ENST00000427674.2
septin 9
chr5_+_140739537 5.07 ENST00000522605.1
protocadherin gamma subfamily B, 2
chrX_+_70503037 5.07 ENST00000535149.1
non-POU domain containing, octamer-binding
chr18_-_34408693 5.01 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
tubulin polyglutamylase complex subunit 2
chr17_+_36861735 4.93 ENST00000378137.5
ENST00000325718.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_-_57583130 4.85 ENST00000303436.6
ADP-ribosylation factor 4
chr12_-_31479045 4.77 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr4_-_83350580 4.73 ENST00000349655.4
ENST00000602300.1
heterogeneous nuclear ribonucleoprotein D-like
chr7_-_107643674 4.69 ENST00000222399.6
laminin, beta 1
chr3_+_196466710 4.64 ENST00000327134.3
p21 protein (Cdc42/Rac)-activated kinase 2
chr3_-_48754599 4.60 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
inositol hexakisphosphate kinase 2
chr4_-_83351294 4.56 ENST00000502762.1
heterogeneous nuclear ribonucleoprotein D-like
chr11_+_111807863 4.55 ENST00000440460.2
DIX domain containing 1
chr8_+_133787586 4.51 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHD finger protein 20-like 1
chrX_-_153599578 4.46 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr9_+_2622085 4.46 ENST00000382099.2
very low density lipoprotein receptor
chr11_+_125496619 4.44 ENST00000532669.1
ENST00000278916.3
checkpoint kinase 1
chr7_+_69064300 4.42 ENST00000342771.4
autism susceptibility candidate 2
chr19_-_1568057 4.41 ENST00000402693.4
ENST00000388824.6
mex-3 RNA binding family member D
chr2_-_2334888 4.40 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr4_-_76598296 4.35 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_200708671 4.29 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr21_-_40720974 4.26 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr2_+_54683419 4.22 ENST00000356805.4
spectrin, beta, non-erythrocytic 1
chr12_+_49212514 4.14 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_1748214 4.11 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
peroxidasin homolog (Drosophila)
chr16_+_14802801 4.10 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr18_-_34409116 4.09 ENST00000334295.4
tubulin polyglutamylase complex subunit 2
chr14_+_75230011 4.04 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLP motif containing 1
chr18_-_34408902 3.98 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
tubulin polyglutamylase complex subunit 2
chr20_-_43150601 3.96 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr15_-_37392703 3.94 ENST00000382766.2
ENST00000444725.1
Meis homeobox 2
chr1_+_164528866 3.90 ENST00000420696.2
pre-B-cell leukemia homeobox 1
chr9_-_139760717 3.85 ENST00000371648.4
endothelial differentiation-related factor 1
chr3_+_9439400 3.82 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SET domain containing 5
chrX_+_12993336 3.79 ENST00000380635.1
thymosin beta 4, X-linked
chr17_-_56605341 3.79 ENST00000583114.1
septin 4
chrX_+_41192595 3.77 ENST00000399959.2
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr5_+_140797296 3.71 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr8_+_126442563 3.64 ENST00000311922.3
tribbles pseudokinase 1
chr11_+_64949899 3.64 ENST00000531068.1
ENST00000527699.1
ENST00000533909.1
ENST00000527323.1
calpain 1, (mu/I) large subunit
chr3_+_9439579 3.64 ENST00000406341.1
SET domain containing 5
chr8_+_11660120 3.62 ENST00000220584.4
farnesyl-diphosphate farnesyltransferase 1
chr21_-_40720995 3.60 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr18_-_21891460 3.55 ENST00000357041.4
oxysterol binding protein-like 1A
chr7_+_16793160 3.50 ENST00000262067.4
tetraspanin 13
chr5_-_43313574 3.50 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_+_45394477 3.49 ENST00000252487.5
ENST00000405636.2
ENST00000592434.1
ENST00000426677.2
ENST00000589649.1
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_+_23146271 3.49 ENST00000545771.1
kelch-like family member 7
chr16_+_67261008 3.47 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chr20_-_34330129 3.43 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
RNA binding motif protein 39
chr16_+_22524844 3.39 ENST00000538606.1
ENST00000424340.1
ENST00000517539.1
ENST00000528249.1
nuclear pore complex interacting protein family, member B5
chr19_-_17375541 3.38 ENST00000252597.3
Usher syndrome 1C binding protein 1
chr14_+_55518349 3.35 ENST00000395468.4
mitogen-activated protein kinase 1 interacting protein 1-like
chr7_-_44887620 3.35 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2A histone family, member V
chr2_+_160568978 3.32 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr8_+_11660227 3.29 ENST00000443614.2
ENST00000525900.1
farnesyl-diphosphate farnesyltransferase 1
chr7_+_18535346 3.29 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr1_-_117210290 3.25 ENST00000369483.1
ENST00000369486.3
immunoglobulin superfamily, member 3
chr19_-_8070474 3.22 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 44.0 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
11.2 55.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
5.9 53.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
4.6 13.7 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
3.5 10.4 GO:1904647 response to rotenone(GO:1904647)
3.4 17.2 GO:0042816 vitamin B6 metabolic process(GO:0042816)
3.2 38.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
2.8 19.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
2.4 9.4 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
2.3 6.9 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
2.3 11.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
2.1 12.9 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.1 21.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
2.1 10.6 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
2.0 6.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
2.0 19.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.9 24.8 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.7 35.9 GO:0051764 actin crosslink formation(GO:0051764)
1.7 25.5 GO:0090168 Golgi reassembly(GO:0090168)
1.7 6.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.6 9.5 GO:0051661 maintenance of centrosome location(GO:0051661)
1.6 4.7 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.4 17.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.4 11.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.4 6.9 GO:0016128 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
1.4 5.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
1.3 7.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.3 19.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
1.3 7.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.3 12.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.2 3.6 GO:0045659 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.2 4.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.2 7.0 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.2 4.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.2 3.5 GO:0006624 vacuolar protein processing(GO:0006624)
1.1 17.7 GO:0045793 positive regulation of cell size(GO:0045793)
1.1 4.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.1 5.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.1 4.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
1.1 10.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
1.1 5.3 GO:0030035 microspike assembly(GO:0030035)
1.1 15.9 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
1.1 4.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.0 10.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.0 3.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
1.0 6.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.0 8.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.9 2.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.9 2.7 GO:0060926 atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.9 4.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.8 5.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 8.5 GO:0030183 B cell differentiation(GO:0030183)
0.8 3.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.7 4.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.7 3.7 GO:0042256 mature ribosome assembly(GO:0042256)
0.7 2.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.7 8.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.6 5.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.6 15.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.6 26.9 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.6 5.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 2.3 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.6 4.0 GO:0009597 detection of virus(GO:0009597)
0.6 3.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
0.6 11.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 2.7 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 2.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 10.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.5 6.9 GO:0090344 negative regulation of cell aging(GO:0090344)
0.5 2.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.5 6.1 GO:0060056 mammary gland involution(GO:0060056)
0.5 2.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.5 1.8 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 4.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.4 2.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 6.1 GO:0045116 protein neddylation(GO:0045116)
0.4 4.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.4 4.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.4 6.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.4 9.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.3 3.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 8.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.3 2.5 GO:0001845 phagolysosome assembly(GO:0001845) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 55.7 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.3 0.9 GO:0072708 response to sorbitol(GO:0072708) cellular response to sorbitol(GO:0072709)
0.3 3.2 GO:0032808 lacrimal gland development(GO:0032808)
0.3 3.5 GO:0009642 response to light intensity(GO:0009642)
0.3 9.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.3 2.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 10.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.3 4.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 2.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 6.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 7.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.3 9.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.3 18.6 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.3 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 10.1 GO:0042407 cristae formation(GO:0042407)
0.3 7.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 2.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2 4.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 11.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.2 3.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 0.9 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) negative regulation of glial cell migration(GO:1903976)
0.2 3.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.2 16.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.2 2.5 GO:0048311 mitochondrion distribution(GO:0048311)
0.2 1.2 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.2 0.8 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.2 6.0 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.2 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 1.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 9.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.2 4.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.2 0.9 GO:0030047 actin modification(GO:0030047)
0.2 6.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 4.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 6.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 1.3 GO:0072718 response to cisplatin(GO:0072718)
0.2 5.8 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.2 2.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 3.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.2 0.3 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 1.0 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 5.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 2.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 2.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 1.1 GO:0001764 neuron migration(GO:0001764)
0.1 6.2 GO:0051983 regulation of chromosome segregation(GO:0051983)
0.1 6.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.1 4.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.9 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.6 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 3.8 GO:0097435 fibril organization(GO:0097435)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 8.1 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 3.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 5.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 8.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 4.3 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.0 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 3.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 5.7 GO:0070125 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1 1.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.9 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 1.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 4.3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 4.3 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 3.9 GO:0008542 visual learning(GO:0008542)
0.1 35.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1 18.8 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.9 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.1 1.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 4.6 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.0 1.3 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 1.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 4.6 GO:0007416 synapse assembly(GO:0007416)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 3.9 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.6 GO:0060065 uterus development(GO:0060065)
0.0 1.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 4.7 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.2 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.0 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.0 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.0 1.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 44.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.2 12.9 GO:0033186 CAF-1 complex(GO:0033186)
2.7 53.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
2.7 21.2 GO:0042382 paraspeckles(GO:0042382)
2.6 10.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.6 7.7 GO:0097447 dendritic tree(GO:0097447)
2.5 17.6 GO:0046581 intercellular canaliculus(GO:0046581)
2.5 17.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
1.8 5.3 GO:0044393 microspike(GO:0044393)
1.6 19.4 GO:0005642 annulate lamellae(GO:0005642)
1.6 4.7 GO:0005607 laminin-2 complex(GO:0005607)
1.5 4.5 GO:0031523 Myb complex(GO:0031523)
1.4 9.5 GO:0036449 microtubule minus-end(GO:0036449)
1.2 13.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.2 7.2 GO:1990357 terminal web(GO:1990357)
1.1 16.7 GO:0005641 nuclear envelope lumen(GO:0005641)
1.1 5.6 GO:0044530 supraspliceosomal complex(GO:0044530)
1.1 25.4 GO:0032156 septin cytoskeleton(GO:0032156)
1.1 4.4 GO:0005694 chromosome(GO:0005694)
1.1 15.8 GO:0030478 actin cap(GO:0030478)
1.0 3.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.9 4.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.8 6.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.8 5.5 GO:0061617 MICOS complex(GO:0061617)
0.8 36.1 GO:0002102 podosome(GO:0002102)
0.7 7.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.7 2.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.6 4.2 GO:0032437 cuticular plate(GO:0032437)
0.6 11.3 GO:0036020 endolysosome membrane(GO:0036020)
0.6 5.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.6 16.9 GO:1990752 microtubule end(GO:1990752)
0.5 2.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5 8.6 GO:0043073 germ cell nucleus(GO:0043073)
0.5 3.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 7.8 GO:0032433 filopodium tip(GO:0032433)
0.4 13.7 GO:0032420 stereocilium(GO:0032420)
0.4 17.3 GO:0031941 filamentous actin(GO:0031941)
0.4 38.9 GO:0043195 terminal bouton(GO:0043195)
0.4 175.5 GO:0005874 microtubule(GO:0005874)
0.4 2.3 GO:0009925 basal plasma membrane(GO:0009925)
0.4 8.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 5.5 GO:0010369 chromocenter(GO:0010369)
0.3 28.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.3 4.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 4.0 GO:0042555 MCM complex(GO:0042555)
0.3 4.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 4.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 18.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 4.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 36.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 1.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 4.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 6.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 6.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 4.6 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.2 17.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 3.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 10.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 5.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 4.2 GO:0043198 dendritic shaft(GO:0043198)
0.1 3.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.1 4.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 5.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 26.6 GO:0031256 leading edge membrane(GO:0031256)
0.1 3.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 11.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 6.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.4 GO:1903349 omegasome membrane(GO:1903349)
0.1 5.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 5.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 4.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 7.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 10.0 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 3.9 GO:0001726 ruffle(GO:0001726)
0.1 9.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 2.0 GO:0016592 mediator complex(GO:0016592)
0.1 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.9 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 17.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 4.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.8 GO:0012506 vesicle membrane(GO:0012506) cytoplasmic vesicle membrane(GO:0030659)
0.0 4.7 GO:0005759 mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.5 10.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
3.2 9.7 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.1 9.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
2.6 10.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.3 6.9 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
1.8 5.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.8 24.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.7 6.9 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
1.4 11.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.4 11.1 GO:0004111 creatine kinase activity(GO:0004111)
1.4 15.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
1.3 9.4 GO:0004849 uridine kinase activity(GO:0004849)
1.3 15.9 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
1.3 7.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.3 7.6 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.1 4.5 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.1 4.5 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
1.1 40.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.9 5.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.9 19.5 GO:0008483 transaminase activity(GO:0008483)
0.9 21.2 GO:0070402 NADPH binding(GO:0070402)
0.9 7.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 7.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.9 3.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 4.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 8.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.8 21.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8 4.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.7 4.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.7 33.1 GO:0003785 actin monomer binding(GO:0003785)
0.7 3.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.6 17.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.6 17.7 GO:0070410 co-SMAD binding(GO:0070410)
0.6 7.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 28.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 13.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.6 9.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.6 12.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.6 15.8 GO:0005523 tropomyosin binding(GO:0005523)
0.6 2.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.5 1.6 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.5 4.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.5 3.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.5 2.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.5 10.4 GO:0004707 MAP kinase activity(GO:0004707)
0.5 12.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 4.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.4 4.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.4 6.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4 4.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 14.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 3.5 GO:0015288 porin activity(GO:0015288)
0.4 126.6 GO:0003924 GTPase activity(GO:0003924)
0.3 17.4 GO:0005080 protein kinase C binding(GO:0005080)
0.3 1.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 10.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 4.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3 6.1 GO:0097602 cullin family protein binding(GO:0097602)
0.3 14.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 12.7 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.2 5.3 GO:0000339 RNA cap binding(GO:0000339)
0.2 17.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 99.1 GO:0045296 cadherin binding(GO:0045296)
0.2 19.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 3.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 4.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 2.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 4.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.7 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997) phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 5.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 6.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 37.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 39.0 GO:0015631 tubulin binding(GO:0015631)
0.1 11.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 5.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 13.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 25.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 3.5 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683) heterotrimeric G-protein binding(GO:0032795)
0.1 1.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 10.6 GO:0005525 GTP binding(GO:0005525)
0.1 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 7.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 3.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 6.5 GO:0008565 protein transporter activity(GO:0008565)
0.1 3.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 2.8 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 3.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 3.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 3.2 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 54.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.9 55.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.7 25.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 35.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 61.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.5 37.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.3 3.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 7.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 16.0 PID AURORA A PATHWAY Aurora A signaling
0.3 11.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2 5.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 6.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 7.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 9.5 PID ATR PATHWAY ATR signaling pathway
0.2 4.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 15.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 15.0 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.2 4.5 PID REELIN PATHWAY Reelin signaling pathway
0.2 2.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 2.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 7.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 5.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 16.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 7.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 7.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 2.3 PID FOXO PATHWAY FoxO family signaling
0.1 6.4 PID NOTCH PATHWAY Notch signaling pathway
0.1 9.9 PID E2F PATHWAY E2F transcription factor network
0.1 2.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 7.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 6.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 5.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 10.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 102.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.3 14.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.2 37.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.0 25.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.0 49.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.8 8.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 19.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 14.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.6 11.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.6 10.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.6 12.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.5 20.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.5 13.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 4.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 3.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4 7.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.4 5.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 17.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.4 29.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.4 9.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.3 36.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.3 6.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 20.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 10.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 3.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.3 8.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 4.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 5.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 28.0 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.3 16.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 4.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 2.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 4.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 4.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 4.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 7.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 6.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 7.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 3.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 7.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 7.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 9.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 5.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 3.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 6.0 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 2.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)