GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SPDEF Links Ensembl NCBI GeneCards UniProt	ENSG00000124664.6	SAM pointed domain containing ETS transcription factor

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SPDEF	hg19_v2_chr6_-_34524093_34524135	-0.36	2.9e-08	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_56082455 Show fit	50.34	ENST00000578794.1	RP11-159D12.5 Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr14_-_69864993 Show fit	46.16	ENST00000555373.1	ERH Links Ensembl NCBI GeneCards UniProt Show fit	enhancer of rudimentary homolog (Drosophila)
chr2_+_198380763 Show fit	37.67	ENST00000448447.2 ENST00000409360.1	MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	MOB family member 4, phocein
chr14_-_24615805 Show fit	35.02	ENST00000560410.1	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_102513843 Show fit	33.35	ENST00000551744.2 ENST00000552283.1	NUP37 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 37kDa
chr1_+_84944926 Show fit	27.56	ENST00000370656.1 ENST00000370654.5	RPF1 Links Ensembl NCBI GeneCards UniProt Show fit	ribosome production factor 1 homolog (S. cerevisiae)
chr14_-_64010046 Show fit	27.46	ENST00000337537.3	PPP2R5E Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr15_-_59949693 Show fit	27.00	ENST00000396063.1 ENST00000396064.3 ENST00000484743.1 ENST00000559706.1 ENST00000396060.2	GTF2A2 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA, 2, 12kDa
chr1_-_193028632 Show fit	26.30	ENST00000421683.1	UCHL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin carboxyl-terminal hydrolase L5
chr8_-_101964265 Show fit	26.07	ENST00000395958.2	YWHAZ Links Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr10_-_120840309 Show fit	25.81	ENST00000369144.3	EIF3A Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3, subunit A
chrX_-_135962876 Show fit	25.22	ENST00000431446.3 ENST00000570135.1 ENST00000320676.7 ENST00000562646.1	RBMX Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein, X-linked
chr1_-_43638168 Show fit	25.06	ENST00000431635.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr5_+_110074685 Show fit	24.96	ENST00000355943.3 ENST00000447245.2	SLC25A46 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25, member 46
chr15_-_59949667 Show fit	24.46	ENST00000396061.1	GTF2A2 Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA, 2, 12kDa
chr17_+_65713925 Show fit	23.73	ENST00000253247.4	NOL11 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 11
chr1_-_193028621 Show fit	23.68	ENST00000367455.4 ENST00000367454.1	UCHL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin carboxyl-terminal hydrolase L5
chr1_+_110091189 Show fit	23.22	ENST00000369851.4	GNAI3 Links Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr14_-_23058063 Show fit	22.95	ENST00000538631.1 ENST00000543337.1 ENST00000250498.4	DAD1 Links Ensembl NCBI GeneCards UniProt Show fit	defender against cell death 1
chr2_+_198380289 Show fit	22.87	ENST00000233892.4 ENST00000409916.1	MOB4 Links Ensembl NCBI GeneCards UniProt Show fit	MOB family member 4, phocein
chr14_+_75348592 Show fit	22.71	ENST00000334220.4	DLST Links Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr15_-_65282232 Show fit	22.18	ENST00000416889.2	SPG21 Links Ensembl NCBI GeneCards UniProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr14_-_67826486 Show fit	22.04	ENST00000555431.1 ENST00000554236.1 ENST00000555474.1	ATP6V1D Links Ensembl NCBI GeneCards UniProt Show fit	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr1_-_67896069 Show fit	21.93	ENST00000370995.2 ENST00000361219.6	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr5_+_892745 Show fit	21.23	ENST00000166345.3	TRIP13 Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 13
chr1_-_43637915 Show fit	21.19	ENST00000236051.2	EBNA1BP2 Links Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr11_-_46142948 Show fit	21.05	ENST00000257821.4	PHF21A Links Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 21A
chr17_-_62658186 Show fit	20.92	ENST00000262435.9	SMURF2 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD specific E3 ubiquitin protein ligase 2
chr1_-_67896095 Show fit	20.51	ENST00000370994.4	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr1_-_67896009 Show fit	20.22	ENST00000370990.5	SERBP1 Links Ensembl NCBI GeneCards UniProt Show fit	SERPINE1 mRNA binding protein 1
chr15_-_65282274 Show fit	20.09	ENST00000204566.2	SPG21 Links Ensembl NCBI GeneCards UniProt Show fit	spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr14_-_24615523 Show fit	20.04	ENST00000559056.1	PSME2 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chrX_+_47053208 Show fit	19.70	ENST00000442035.1 ENST00000457753.1 ENST00000335972.6	UBA1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like modifier activating enzyme 1
chr12_+_69080734 Show fit	19.68	ENST00000378905.2	NUP107 Links Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 107kDa
chr1_-_19811996 Show fit	18.74	ENST00000264203.3 ENST00000401084.2	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping protein (actin filament) muscle Z-line, beta
chr14_+_35761580 Show fit	18.70	ENST00000553809.1 ENST00000555764.1 ENST00000556506.1	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 6
chr3_-_133380731 Show fit	18.51	ENST00000260810.5	TOPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	topoisomerase (DNA) II binding protein 1
chr11_-_71823796 Show fit	18.32	ENST00000545680.1 ENST00000543587.1 ENST00000538393.1 ENST00000535234.1 ENST00000227618.4 ENST00000535503.1	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chrX_+_69509927 Show fit	17.97	ENST00000374403.3	KIF4A Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 4A
chr12_-_121019165 Show fit	17.69	ENST00000341039.2 ENST00000357500.4	POP5 Links Ensembl NCBI GeneCards UniProt Show fit	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr5_+_86564739 Show fit	17.56	ENST00000456692.2 ENST00000512763.1 ENST00000506290.1	RASA1 Links Ensembl NCBI GeneCards UniProt Show fit	RAS p21 protein activator (GTPase activating protein) 1
chr14_+_60715928 Show fit	17.40	ENST00000395076.4	PPM1A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_-_2451395 Show fit	17.28	ENST00000339610.6 ENST00000381342.2 ENST00000438552.2	SNRPB Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr22_+_44351419 Show fit	17.04	ENST00000396202.3	SAMM50 Links Ensembl NCBI GeneCards UniProt Show fit	SAMM50 sorting and assembly machinery component
chr5_-_31532160 Show fit	16.84	ENST00000511367.2 ENST00000513349.1	DROSHA Links Ensembl NCBI GeneCards UniProt Show fit	drosha, ribonuclease type III
chr1_-_193028426 Show fit	16.76	ENST00000367450.3 ENST00000530098.2 ENST00000367451.4 ENST00000367448.1 ENST00000367449.1	UCHL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin carboxyl-terminal hydrolase L5
chr14_-_21737551 Show fit	16.68	ENST00000554891.1 ENST00000555883.1 ENST00000553753.1 ENST00000555914.1 ENST00000557336.1 ENST00000555215.1 ENST00000556628.1 ENST00000555137.1 ENST00000556226.1 ENST00000555309.1 ENST00000556142.1 ENST00000554969.1 ENST00000554455.1 ENST00000556513.1 ENST00000557201.1 ENST00000420743.2 ENST00000557768.1 ENST00000553300.1 ENST00000554383.1 ENST00000554539.1	HNRNPC Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr7_+_98923505 Show fit	16.48	ENST00000432884.2 ENST00000262942.5	ARPC1A Links Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex, subunit 1A, 41kDa
chr14_+_35761540 Show fit	16.41	ENST00000261479.4	PSMA6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, alpha type, 6
chr8_-_117768023 Show fit	16.11	ENST00000518949.1 ENST00000522453.1 ENST00000521861.1 ENST00000518995.1	EIF3H Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3, subunit H
chrX_-_153775426 Show fit	15.42	ENST00000393562.2	G6PD Links Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphate dehydrogenase
chr14_-_21737610 Show fit	15.42	ENST00000320084.7 ENST00000449098.1 ENST00000336053.6	HNRNPC Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr19_+_58898627 Show fit	15.31	ENST00000598098.1 ENST00000598495.1 ENST00000196551.3 ENST00000596046.1	RPS5 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S5
chr4_-_10118348 Show fit	15.26	ENST00000502702.1	WDR1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr11_-_71823266 Show fit	15.14	ENST00000538919.1 ENST00000539395.1 ENST00000542531.1	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr5_+_31532373 Show fit	15.03	ENST00000325366.9 ENST00000355907.3 ENST00000507818.2	C5orf22 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 22
chr6_+_134274322 Show fit	15.02	ENST00000367871.1 ENST00000237264.4	TBPL1 Links Ensembl NCBI GeneCards UniProt Show fit	TBP-like 1
chr1_+_43124087 Show fit	14.95	ENST00000304979.3 ENST00000372550.1 ENST00000440068.1	PPIH Links Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase H (cyclophilin H)
chr2_+_187350883 Show fit	14.85	ENST00000337859.6	ZC3H15 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 15
chr22_+_44351301 Show fit	14.82	ENST00000350028.4	SAMM50 Links Ensembl NCBI GeneCards UniProt Show fit	SAMM50 sorting and assembly machinery component
chrX_+_47444613 Show fit	14.78	ENST00000445623.1	TIMP1 Links Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr8_-_56987057 Show fit	14.54	ENST00000518875.1	RPS20 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S20
chr11_-_71823715 Show fit	14.51	ENST00000545944.1 ENST00000502597.2	ANAPC15 Links Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr2_+_65454926 Show fit	14.50	ENST00000542850.1 ENST00000377982.4	ACTR2 Links Ensembl NCBI GeneCards UniProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr1_+_235492300 Show fit	14.47	ENST00000476121.1 ENST00000497327.1	GGPS1 Links Ensembl NCBI GeneCards UniProt Show fit	geranylgeranyl diphosphate synthase 1
chr1_-_19811962 Show fit	14.20	ENST00000375142.1 ENST00000264202.6	CAPZB Links Ensembl NCBI GeneCards UniProt Show fit	capping protein (actin filament) muscle Z-line, beta
chr1_+_151129135 Show fit	13.65	ENST00000602841.1	SCNM1 Links Ensembl NCBI GeneCards UniProt Show fit	sodium channel modifier 1
chr14_+_67826709 Show fit	13.61	ENST00000256383.4	EIF2S1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr13_+_27998681 Show fit	13.44	ENST00000381140.4	GTF3A Links Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIIA
chr8_-_130951940 Show fit	13.27	ENST00000522250.1 ENST00000522941.1 ENST00000522746.1 ENST00000520204.1 ENST00000519070.1 ENST00000520254.1 ENST00000519824.2 ENST00000519540.1	FAM49B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 49, member B
chr11_+_63754294 Show fit	13.26	ENST00000543988.1	OTUB1 Links Ensembl NCBI GeneCards UniProt Show fit	OTU domain, ubiquitin aldehyde binding 1
chr19_+_19496624 Show fit	13.26	ENST00000494516.2 ENST00000360315.3 ENST00000252577.5	GATAD2A Links Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2A
chr20_-_34252759 Show fit	13.22	ENST00000414711.1 ENST00000416778.1 ENST00000397442.1 ENST00000440240.1 ENST00000412056.1 ENST00000352393.4 ENST00000458038.1 ENST00000420363.1 ENST00000434795.1 ENST00000437100.1 ENST00000414664.1 ENST00000359646.1 ENST00000424458.1 ENST00000374104.3 ENST00000374114.3	CPNE1 Links Ensembl NCBI GeneCards UniProt Show fit RBM12 Links Ensembl NCBI GeneCards UniProt Show fit	copine I RNA binding motif protein 12
chr2_+_187350973 Show fit	12.99	ENST00000544130.1	ZC3H15 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 15
chr3_-_32022733 Show fit	12.91	ENST00000438237.2 ENST00000396556.2	OSBPL10 Links Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein-like 10
chr2_+_65454863 Show fit	12.86	ENST00000260641.5	ACTR2 Links Ensembl NCBI GeneCards UniProt Show fit	ARP2 actin-related protein 2 homolog (yeast)
chr1_-_235324530 Show fit	12.80	ENST00000447801.1 ENST00000366606.3 ENST00000429912.1	RBM34 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 34
chr3_+_33840050 Show fit	12.69	ENST00000457054.2 ENST00000413073.1	PDCD6IP Links Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6 interacting protein
chr3_-_196669248 Show fit	12.44	ENST00000447325.1	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr7_+_44240520 Show fit	12.34	ENST00000496112.1 ENST00000223369.2	YKT6 Links Ensembl NCBI GeneCards UniProt Show fit	YKT6 v-SNARE homolog (S. cerevisiae)
chr1_+_84630645 Show fit	12.14	ENST00000394839.2	PRKACB Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr17_+_65714018 Show fit	12.12	ENST00000581106.1 ENST00000535137.1	NOL11 Links Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 11
chr1_-_235324772 Show fit	12.10	ENST00000408888.3	RBM34 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 34
chr7_-_6098770 Show fit	11.97	ENST00000536084.1 ENST00000446699.1 ENST00000199389.6	EIF2AK1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2-alpha kinase 1
chr6_-_170862322 Show fit	11.97	ENST00000262193.6	PSMB1 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) subunit, beta type, 1
chr17_-_56065484 Show fit	11.92	ENST00000581208.1	VEZF1 Links Ensembl NCBI GeneCards UniProt Show fit	vascular endothelial zinc finger 1
chr11_+_57480046 Show fit	11.69	ENST00000378312.4 ENST00000278422.4	TMX2 Links Ensembl NCBI GeneCards UniProt Show fit	thioredoxin-related transmembrane protein 2
chr10_+_75504105 Show fit	11.60	ENST00000535742.1 ENST00000546025.1 ENST00000345254.4 ENST00000540668.1 ENST00000339365.2 ENST00000411652.2	SEC24C Links Ensembl NCBI GeneCards UniProt Show fit	SEC24 family member C
chr19_+_9938562 Show fit	11.28	ENST00000586895.1 ENST00000358666.3 ENST00000590068.1 ENST00000593087.1	UBL5 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like 5
chr14_+_24701819 Show fit	11.16	ENST00000560139.1 ENST00000559910.1	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr7_+_128379346 Show fit	11.12	ENST00000535011.2 ENST00000542996.2 ENST00000535623.1 ENST00000538546.1 ENST00000249364.4 ENST00000449187.2	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr13_+_25670268 Show fit	10.95	ENST00000281589.3	PABPC3 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 3
chr14_+_24702073 Show fit	10.93	ENST00000399440.2	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr3_-_196669298 Show fit	10.86	ENST00000411704.1 ENST00000452404.2	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chr3_+_100428316 Show fit	10.63	ENST00000479672.1 ENST00000476228.1 ENST00000463568.1	TFG Links Ensembl NCBI GeneCards UniProt Show fit	TRK-fused gene
chr20_-_34252847 Show fit	10.53	ENST00000317619.3 ENST00000397446.1 ENST00000397445.1 ENST00000397443.1 ENST00000430570.1 ENST00000439806.2 ENST00000437340.1 ENST00000435161.1 ENST00000431148.1	CPNE1 Links Ensembl NCBI GeneCards UniProt Show fit RBM12 Links Ensembl NCBI GeneCards UniProt Show fit	copine I RNA binding motif protein 12
chr19_+_7701985 Show fit	10.38	ENST00000595950.1 ENST00000441779.2 ENST00000221283.5 ENST00000414284.2	STXBP2 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 2
chr17_-_74733404 Show fit	10.27	ENST00000508921.3 ENST00000583836.1 ENST00000358156.6 ENST00000392485.2 ENST00000359995.5	SRSF2 Links Ensembl NCBI GeneCards UniProt Show fit	serine/arginine-rich splicing factor 2
chr1_-_20987851 Show fit	10.24	ENST00000464364.1 ENST00000602624.2	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr14_-_24701539 Show fit	10.21	ENST00000534348.1 ENST00000524927.1 ENST00000250495.5	NEDD8-MDP1 Links Ensembl NCBI GeneCards UniProt Show fit NEDD8 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD8-MDP1 readthrough neural precursor cell expressed, developmentally down-regulated 8
chr7_+_77428149 Show fit	10.17	ENST00000415251.2 ENST00000275575.7	PHTF2 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr12_-_49961883 Show fit	10.14	ENST00000553173.1 ENST00000550165.1 ENST00000546244.1 ENST00000343810.4	MCRS1 Links Ensembl NCBI GeneCards UniProt Show fit	microspherule protein 1
chr3_+_100428268 Show fit	10.08	ENST00000240851.4	TFG Links Ensembl NCBI GeneCards UniProt Show fit	TRK-fused gene
chr7_+_128379449 Show fit	10.03	ENST00000479257.1	CALU Links Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr2_-_128784846 Show fit	9.95	ENST00000259235.3 ENST00000357702.5 ENST00000424298.1	SAP130 Links Ensembl NCBI GeneCards UniProt Show fit	Sin3A-associated protein, 130kDa
chr16_+_70557685 Show fit	9.91	ENST00000302516.5 ENST00000566095.2 ENST00000577085.1 ENST00000567654.1	SF3B3 Links Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3b, subunit 3, 130kDa
chr18_+_21032781 Show fit	9.87	ENST00000339486.3	RIOK3 Links Ensembl NCBI GeneCards UniProt Show fit	RIO kinase 3
chr1_-_20987889 Show fit	9.82	ENST00000415136.2	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr12_+_50135588 Show fit	9.81	ENST00000423828.1 ENST00000550445.1	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr20_+_34129770 Show fit	9.70	ENST00000348547.2 ENST00000357394.4 ENST00000447986.1 ENST00000279052.6 ENST00000416206.1 ENST00000411577.1 ENST00000413587.1	ERGIC3 Links Ensembl NCBI GeneCards UniProt Show fit	ERGIC and golgi 3
chr11_+_73498898 Show fit	9.60	ENST00000535529.1 ENST00000497094.2 ENST00000411840.2 ENST00000535277.1 ENST00000398483.3 ENST00000542303.1	MRPL48 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L48
chr14_+_24701628 Show fit	9.58	ENST00000355299.4 ENST00000559836.1	GMPR2 Links Ensembl NCBI GeneCards UniProt Show fit	guanosine monophosphate reductase 2
chr2_+_96931834 Show fit	9.47	ENST00000488633.1	CIAO1 Links Ensembl NCBI GeneCards UniProt Show fit	cytosolic iron-sulfur protein assembly 1
chr8_-_101734170 Show fit	9.38	ENST00000522387.1 ENST00000518196.1	PABPC1 Links Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr19_+_41257084 Show fit	9.15	ENST00000601393.1	SNRPA Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr6_+_7541808 Show fit	9.13	ENST00000379802.3	DSP Links Ensembl NCBI GeneCards UniProt Show fit	desmoplakin
chr15_+_44092784 Show fit	9.12	ENST00000458412.1	HYPK Links Ensembl NCBI GeneCards UniProt Show fit	huntingtin interacting protein K
chr8_-_101965146 Show fit	9.08	ENST00000395957.2 ENST00000395948.2 ENST00000457309.1	YWHAZ Links Ensembl NCBI GeneCards UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr4_-_10118573 Show fit	8.88	ENST00000382452.2 ENST00000382451.2	WDR1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr22_-_41215291 Show fit	8.80	ENST00000542412.1 ENST00000544408.1	SLC25A17 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr3_+_100428188 Show fit	8.80	ENST00000418917.2 ENST00000490574.1	TFG Links Ensembl NCBI GeneCards UniProt Show fit	TRK-fused gene
chr11_-_58345569 Show fit	8.76	ENST00000528954.1 ENST00000528489.1	LPXN Links Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr20_+_60962143 Show fit	8.70	ENST00000343986.4	RPS21 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S21
chr2_+_63816087 Show fit	8.61	ENST00000409908.1 ENST00000442225.1 ENST00000409476.1 ENST00000436321.1	MDH1 Links Ensembl NCBI GeneCards UniProt Show fit	malate dehydrogenase 1, NAD (soluble)
chr5_-_177580855 Show fit	8.45	ENST00000514354.1 ENST00000511078.1	NHP2 Links Ensembl NCBI GeneCards UniProt Show fit	NHP2 ribonucleoprotein
chr7_+_93551011 Show fit	8.40	ENST00000248564.5	GNG11 Links Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), gamma 11
chr17_-_47755436 Show fit	8.37	ENST00000505581.1 ENST00000514121.1 ENST00000393328.2 ENST00000509079.1 ENST00000393331.3 ENST00000347630.2 ENST00000504102.1	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle-type POZ protein
chr3_-_196669371 Show fit	8.36	ENST00000427641.2 ENST00000321256.5	NCBP2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear cap binding protein subunit 2, 20kDa
chrX_-_131352152 Show fit	8.15	ENST00000342983.2	RAP2C Links Ensembl NCBI GeneCards UniProt Show fit	RAP2C, member of RAS oncogene family
chr4_-_83812402 Show fit	7.71	ENST00000395310.2	SEC31A Links Ensembl NCBI GeneCards UniProt Show fit	SEC31 homolog A (S. cerevisiae)
chr4_-_83295103 Show fit	7.62	ENST00000313899.7 ENST00000352301.4 ENST00000509107.1 ENST00000353341.4 ENST00000541060.1	HNRNPD Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr1_-_169337176 Show fit	7.53	ENST00000472647.1 ENST00000367811.3	NME7 Links Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 7
chr7_+_100273736 Show fit	7.50	ENST00000412215.1 ENST00000393924.1	GNB2 Links Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_+_41992489 Show fit	7.49	ENST00000264451.7	SLC30A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 (zinc transporter), member 9
chr12_+_102513950 Show fit	7.40	ENST00000378128.3 ENST00000327680.2 ENST00000541394.1 ENST00000543784.1	PARPBP Links Ensembl NCBI GeneCards UniProt Show fit	PARP1 binding protein
chrX_-_152486108 Show fit	7.35	ENST00000356661.5	MAGEA1 Links Ensembl NCBI GeneCards UniProt Show fit	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr12_+_50794592 Show fit	7.13	ENST00000293618.8 ENST00000429001.3 ENST00000548174.1 ENST00000548697.1 ENST00000548993.1 ENST00000398473.2 ENST00000522085.1 ENST00000518444.1 ENST00000551886.1	LARP4 Links Ensembl NCBI GeneCards UniProt Show fit	La ribonucleoprotein domain family, member 4
chr8_-_77912431 Show fit	7.11	ENST00000357039.4 ENST00000522527.1	PEX2 Links Ensembl NCBI GeneCards UniProt Show fit	peroxisomal biogenesis factor 2
chr5_-_177580933 Show fit	6.97	ENST00000274606.3	NHP2 Links Ensembl NCBI GeneCards UniProt Show fit	NHP2 ribonucleoprotein
chr2_+_178077477 Show fit	6.87	ENST00000411529.2 ENST00000435711.1	HNRNPA3 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein A3
chr1_+_193028552 Show fit	6.86	ENST00000400968.2 ENST00000432079.1	TROVE2 Links Ensembl NCBI GeneCards UniProt Show fit	TROVE domain family, member 2
chr7_+_77428066 Show fit	6.76	ENST00000422959.2 ENST00000307305.8 ENST00000424760.1	PHTF2 Links Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr6_+_33257427 Show fit	6.64	ENST00000463584.1	PFDN6 Links Ensembl NCBI GeneCards UniProt Show fit	prefoldin subunit 6
chr1_-_20987982 Show fit	6.55	ENST00000375048.3	DDOST Links Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
chr1_+_24117627 Show fit	6.50	ENST00000400061.1	LYPLA2 Links Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase II
chr1_+_84630053 Show fit	6.37	ENST00000394838.2 ENST00000370682.3 ENST00000432111.1	PRKACB Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase, cAMP-dependent, catalytic, beta
chr14_+_89029253 Show fit	6.37	ENST00000251038.5 ENST00000359301.3 ENST00000302216.8	ZC3H14 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr1_+_39456895 Show fit	6.37	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1 Links Ensembl NCBI GeneCards UniProt Show fit	akirin 1
chrX_+_123480194 Show fit	6.31	ENST00000371139.4	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr4_-_83812248 Show fit	6.24	ENST00000514326.1 ENST00000505434.1 ENST00000503058.1 ENST00000348405.4 ENST00000505984.1 ENST00000513858.1 ENST00000508479.1 ENST00000443462.2 ENST00000508502.1 ENST00000509142.1 ENST00000432794.1 ENST00000448323.1 ENST00000326950.5 ENST00000311785.7	SEC31A Links Ensembl NCBI GeneCards UniProt Show fit	SEC31 homolog A (S. cerevisiae)
chr7_+_114562172 Show fit	6.16	ENST00000393486.1 ENST00000257724.3	MDFIC Links Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor domain containing
chr15_-_65810042 Show fit	6.15	ENST00000321147.6	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl-peptidase 8
chr4_-_10118469 Show fit	6.09	ENST00000499869.2	WDR1 Links Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr1_+_24117693 Show fit	6.07	ENST00000374503.3 ENST00000374502.3	LYPLA2 Links Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase II
chr3_-_139108475 Show fit	6.06	ENST00000515006.1 ENST00000513274.1 ENST00000514508.1 ENST00000507777.1 ENST00000512153.1 ENST00000333188.5	COPB2 Links Ensembl NCBI GeneCards UniProt Show fit	coatomer protein complex, subunit beta 2 (beta prime)
chr15_-_65809991 Show fit	5.93	ENST00000559526.1 ENST00000358939.4 ENST00000560665.1 ENST00000321118.7 ENST00000339244.5 ENST00000300141.6	DPP8 Links Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl-peptidase 8
chr9_+_36190905 Show fit	5.89	ENST00000345519.5 ENST00000470744.1 ENST00000242285.6 ENST00000466396.1 ENST00000396603.2	CLTA Links Ensembl NCBI GeneCards UniProt Show fit	clathrin, light chain A
chr11_-_33183006 Show fit	5.75	ENST00000524827.1 ENST00000323959.4 ENST00000431742.2	CSTF3 Links Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr6_+_43484760 Show fit	5.75	ENST00000372389.3 ENST00000372344.2 ENST00000304004.3 ENST00000423780.1	POLR1C Links Ensembl NCBI GeneCards UniProt Show fit	polymerase (RNA) I polypeptide C, 30kDa
chr9_+_36190853 Show fit	5.52	ENST00000433436.2 ENST00000538225.1 ENST00000540080.1	CLTA Links Ensembl NCBI GeneCards UniProt Show fit	clathrin, light chain A
chr19_-_12780211 Show fit	5.52	ENST00000597961.1 ENST00000598732.1 ENST00000222190.5	CTD-2192J16.24 Links Ensembl NCBI GeneCards UniProt Show fit WDR83OS Links Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein WD repeat domain 83 opposite strand
chr6_-_116381918 Show fit	5.43	ENST00000606080.1	FRK Links Ensembl NCBI GeneCards UniProt Show fit	fyn-related kinase
chrX_+_123480375 Show fit	5.28	ENST00000360027.4	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr6_-_31560729 Show fit	5.27	ENST00000340027.5 ENST00000376073.4 ENST00000376072.3	NCR3 Links Ensembl NCBI GeneCards UniProt Show fit	natural cytotoxicity triggering receptor 3
chr1_-_156698181 Show fit	5.17	ENST00000313146.6	ISG20L2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon stimulated exonuclease gene 20kDa-like 2
chr12_+_120972147 Show fit	5.14	ENST00000325954.4 ENST00000542438.1	RNF10 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 10
chr11_+_111957497 Show fit	5.13	ENST00000375549.3 ENST00000528182.1 ENST00000528048.1 ENST00000528021.1 ENST00000526592.1 ENST00000525291.1	SDHD Links Ensembl NCBI GeneCards UniProt Show fit	succinate dehydrogenase complex, subunit D, integral membrane protein
chr16_-_28503357 Show fit	5.12	ENST00000333496.9 ENST00000561505.1 ENST00000567963.1 ENST00000354630.5 ENST00000355477.5 ENST00000357076.5 ENST00000565688.1 ENST00000359984.7	CLN3 Links Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr19_-_1650666 Show fit	5.04	ENST00000588136.1	TCF3 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 3
chr14_-_78083112 Show fit	4.98	ENST00000216484.2	SPTLC2 Links Ensembl NCBI GeneCards UniProt Show fit	serine palmitoyltransferase, long chain base subunit 2
chr16_-_28503327 Show fit	4.92	ENST00000535392.1 ENST00000395653.4	CLN3 Links Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr12_+_54422142 Show fit	4.92	ENST00000243108.4	HOXC6 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox C6
chr16_+_31044812 Show fit	4.88	ENST00000313843.3	STX4 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 4
chr8_+_15397732 Show fit	4.75	ENST00000382020.4 ENST00000506802.1 ENST00000509380.1 ENST00000503731.1	TUSC3 Links Ensembl NCBI GeneCards UniProt Show fit	tumor suppressor candidate 3
chr11_-_111957451 Show fit	4.71	ENST00000504148.2 ENST00000541231.1	TIMM8B Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr16_-_28503080 Show fit	4.58	ENST00000565316.1 ENST00000565778.1 ENST00000357857.9 ENST00000568558.1 ENST00000357806.7	CLN3 Links Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr22_+_38201114 Show fit	4.52	ENST00000340857.2	H1F0 Links Ensembl NCBI GeneCards UniProt Show fit	H1 histone family, member 0
chr8_-_56986768 Show fit	4.49	ENST00000523936.1	RPS20 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S20
chr6_-_42713792 Show fit	4.28	ENST00000372876.1	TBCC Links Ensembl NCBI GeneCards UniProt Show fit	tubulin folding cofactor C
chr20_-_42839378 Show fit	4.26	ENST00000255174.2	OSER1 Links Ensembl NCBI GeneCards UniProt Show fit	oxidative stress responsive serine-rich 1
chr5_-_892648 Show fit	4.26	ENST00000483173.1 ENST00000435709.2	BRD9 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 9
chr20_-_62199427 Show fit	4.12	ENST00000427522.2	HELZ2 Links Ensembl NCBI GeneCards UniProt Show fit	helicase with zinc finger 2, transcriptional coactivator
chr7_-_38948774 Show fit	4.11	ENST00000395969.2 ENST00000414632.1 ENST00000310301.4	VPS41 Links Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 41 homolog (S. cerevisiae)
chr7_-_91875109 Show fit	4.09	ENST00000412043.2 ENST00000430102.1 ENST00000425073.1 ENST00000394503.2 ENST00000454017.1 ENST00000440209.1 ENST00000413688.1 ENST00000452773.1 ENST00000433016.1 ENST00000394505.2 ENST00000422347.1 ENST00000458493.1 ENST00000425919.1	KRIT1 Links Ensembl NCBI GeneCards UniProt Show fit	KRIT1, ankyrin repeat containing
chrX_+_123480421 Show fit	4.05	ENST00000477673.2	SH2D1A Links Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr5_-_114961858 Show fit	4.02	ENST00000282382.4 ENST00000456936.3 ENST00000408996.4	TMED7-TICAM2 Links Ensembl NCBI GeneCards UniProt Show fit TMED7 Links Ensembl NCBI GeneCards UniProt Show fit TICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	TMED7-TICAM2 readthrough transmembrane emp24 protein transport domain containing 7 toll-like receptor adaptor molecule 2
chr12_-_123187890 Show fit	4.02	ENST00000328880.5	HCAR2 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 2
chr12_+_50135351 Show fit	3.90	ENST00000549445.1 ENST00000550951.1 ENST00000549385.1 ENST00000548713.1 ENST00000548201.1	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr7_+_6414128 Show fit	3.49	ENST00000348035.4 ENST00000356142.4	RAC1 Links Ensembl NCBI GeneCards UniProt Show fit	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr1_-_111506562 Show fit	3.20	ENST00000485275.2 ENST00000369763.4	LRIF1 Links Ensembl NCBI GeneCards UniProt Show fit	ligand dependent nuclear receptor interacting factor 1
chr12_+_50135327 Show fit	3.13	ENST00000549966.1 ENST00000547832.1 ENST00000547187.1 ENST00000548894.1 ENST00000546914.1 ENST00000552699.1 ENST00000267115.5	TMBIM6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr10_+_5726764 Show fit	3.05	ENST00000328090.5 ENST00000496681.1	FAM208B Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 208, member B
chrX_+_49091920 Show fit	3.04	ENST00000376227.3	CCDC22 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 22
chr14_+_60716159 Show fit	2.98	ENST00000325658.3	PPM1A Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_-_33999766 Show fit	2.94	ENST00000349714.5 ENST00000438533.1 ENST00000359226.2 ENST00000374384.2 ENST00000374377.5 ENST00000407996.2 ENST00000424405.1 ENST00000542501.1 ENST00000397554.1 ENST00000540457.1 ENST00000374380.2 ENST00000374385.5	UQCC1 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquinol-cytochrome c reductase complex assembly factor 1
chr14_+_89029366 Show fit	2.92	ENST00000555799.1 ENST00000555755.1 ENST00000393514.5	ZC3H14 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr14_+_22931924 Show fit	2.87	ENST00000390477.2	TRDC Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor delta constant
chr19_+_41256764 Show fit	2.77	ENST00000243563.3 ENST00000601253.1 ENST00000597353.1 ENST00000599362.1	SNRPA Links Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr14_+_89029336 Show fit	2.68	ENST00000556945.1 ENST00000556158.1 ENST00000557607.1	ZC3H14 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 14
chr2_+_162016804 Show fit	2.48	ENST00000392749.2 ENST00000440506.1	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member-associated NFKB activator

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.1	27.4	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
8.6	25.8	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
8.3	25.0	GO:0090149	mitochondrial membrane fission(GO:0090149)
7.9	31.7	GO:0046833	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
7.6	22.7	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
7.6	30.2	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
6.6	32.9	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
5.2	20.9	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
5.1	15.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
4.5	13.6	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
4.2	12.7	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
4.2	66.7	GO:0021670	lateral ventricle development(GO:0021670)
3.9	19.7	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
3.8	15.0	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
3.7	18.5	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
3.7	18.5	GO:0097338	response to clozapine(GO:0097338)
3.7	14.6	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
3.4	20.4	GO:0006499	N-terminal protein myristoylation(GO:0006499)
3.4	10.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
3.1	15.4	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
3.0	12.0	GO:0006447	regulation of translational initiation by iron(GO:0006447)
2.9	31.9	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
2.8	16.8	GO:0060701	negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
2.8	35.9	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
2.7	46.0	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
2.6	7.7	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.5	7.6	GO:1901355	response to rapamycin(GO:1901355)
2.5	7.6	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
2.5	12.6	GO:0002084	protein depalmitoylation(GO:0002084)
2.3	35.1	GO:0090168	Golgi reassembly(GO:0090168)
2.3	6.8	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
2.2	13.3	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
2.2	23.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
2.1	21.2	GO:0007144	female meiosis I(GO:0007144)
1.9	13.3	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.8	14.8	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
1.8	17.7	GO:0009249	protein lipoylation(GO:0009249)
1.8	5.3	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.7	5.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.7	16.8	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
1.6	4.9	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
1.3	53.7	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
1.3	9.1	GO:0071896	protein localization to adherens junction(GO:0071896)
1.3	32.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.3	25.5	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
1.3	31.7	GO:0006144	purine nucleobase metabolic process(GO:0006144)
1.3	25.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.3	23.9	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
1.2	5.0	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.2	18.0	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
1.2	3.5	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
1.1	8.8	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
1.1	8.7	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
1.1	27.6	GO:0000470	maturation of LSU-rRNA(GO:0000470)
1.0	9.4	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.0	58.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
1.0	44.3	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
1.0	102.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.9	10.2	GO:0045116	protein neddylation(GO:0045116)
0.9	51.2	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.8	4.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.8	4.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.8	15.6	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.7	33.4	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.7	2.9	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.7	8.6	GO:0006108	malate metabolic process(GO:0006108)
0.7	4.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.7	15.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.7	4.0	GO:0071651	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.6	22.0	GO:0090383	phagosome acidification(GO:0090383)
0.6	5.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.6	5.0	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.6	17.3	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.6	11.4	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.6	62.6	GO:0043488	regulation of mRNA stability(GO:0043488)
0.6	12.9	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.6	9.4	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.5	10.3	GO:0033197	response to vitamin E(GO:0033197)
0.5	23.2	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.5	1.0	GO:2000644	regulation of receptor catabolic process(GO:2000644)
0.4	23.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.4	29.5	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4	17.6	GO:0000281	mitotic cytokinesis(GO:0000281)
0.3	15.9	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.3	13.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.3	13.7	GO:0008380	RNA splicing(GO:0008380)
0.3	5.8	GO:0006379	mRNA cleavage(GO:0006379)
0.3	1.8	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	2.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.2	7.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.2	7.3	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	16.1	GO:0006446	regulation of translational initiation(GO:0006446)
0.2	3.0	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2	4.5	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.2	5.5	GO:2000352	negative regulation of endothelial cell apoptotic process(GO:2000352)
0.2	11.9	GO:0001885	endothelial cell development(GO:0001885)
0.2	5.8	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.2	6.2	GO:0007257	activation of JUN kinase activity(GO:0007257) positive regulation of viral transcription(GO:0050434)
0.1	4.6	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.1	9.6	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1	6.1	GO:1901998	toxin transport(GO:1901998)
0.1	26.8	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.1	6.2	GO:0002181	cytoplasmic translation(GO:0002181)
0.1	13.0	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1	5.4	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	7.5	GO:0006289	nucleotide-excision repair(GO:0006289)
0.1	21.1	GO:0007596	blood coagulation(GO:0007596)
0.0	0.2	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0	1.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	4.7	GO:0007605	sensory perception of sound(GO:0007605)
0.0	11.5	GO:0043687	post-translational protein modification(GO:0043687)
0.0	0.7	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	3.6	GO:0051028	mRNA transport(GO:0051028)
0.0	2.2	GO:0007186	G-protein coupled receptor signaling pathway(GO:0007186)
0.0	0.1	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0	0.1	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.7	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	1.5	GO:0006909	phagocytosis(GO:0006909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
12.0	35.9	GO:0034455	t-UTP complex(GO:0034455)
9.2	55.1	GO:0008537	proteasome activator complex(GO:0008537)
8.3	66.5	GO:0005672	transcription factor TFIIA complex(GO:0005672)
7.9	31.7	GO:0005846	nuclear cap binding complex(GO:0005846)
6.0	30.2	GO:0042643	actomyosin, actin portion(GO:0042643)
5.3	31.7	GO:1902560	GMP reductase complex(GO:1902560)
5.0	25.2	GO:0044530	supraspliceosomal complex(GO:0044530)
4.7	32.9	GO:0071203	WASH complex(GO:0071203)
4.7	41.9	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.5	13.6	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
4.5	54.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
4.1	12.3	GO:0097441	basilar dendrite(GO:0097441)
3.7	15.0	GO:0071001	U4/U6 snRNP(GO:0071001)
3.7	76.9	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
3.5	63.4	GO:0034709	methylosome(GO:0034709)
3.3	53.0	GO:0031080	nuclear pore outer ring(GO:0031080)
3.2	22.7	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
2.9	35.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
2.9	31.9	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
2.8	39.7	GO:0001673	male germ cell nucleus(GO:0001673)
2.6	15.4	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
2.5	17.7	GO:0000172	ribonuclease MRP complex(GO:0000172)
2.4	73.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
2.3	43.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
2.1	10.3	GO:0035061	interchromatin granule(GO:0035061)
2.0	56.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.9	21.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
1.8	16.2	GO:0071439	clathrin complex(GO:0071439)
1.6	48.0	GO:0005680	anaphase-promoting complex(GO:0005680)
1.6	9.5	GO:0071817	MMXD complex(GO:0071817)
1.4	42.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
1.3	32.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
1.3	5.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.3	7.6	GO:0030688	preribosome, small subunit precursor(GO:0030688)
1.2	5.0	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.2	15.6	GO:0030127	COPII vesicle coat(GO:0030127)
1.2	10.4	GO:0044194	cytolytic granule(GO:0044194)
1.0	16.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
1.0	17.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.9	18.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.9	28.8	GO:0030057	desmosome(GO:0030057)
0.8	27.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.7	12.0	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.7	7.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.7	22.0	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.7	60.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.7	6.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.7	4.6	GO:0016272	prefoldin complex(GO:0016272)
0.6	4.7	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.6	31.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.6	9.9	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.6	41.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.5	16.8	GO:1902555	endoribonuclease complex(GO:1902555)
0.5	11.9	GO:0005685	U1 snRNP(GO:0005685)
0.5	44.3	GO:0000118	histone deacetylase complex(GO:0000118)
0.4	4.9	GO:0035749	myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.4	18.0	GO:1904115	axon cytoplasm(GO:1904115)
0.4	23.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	5.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.3	1.8	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.2	38.6	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	9.6	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	28.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.2	14.6	GO:0005795	Golgi stack(GO:0005795)
0.2	10.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2	8.8	GO:0002102	podosome(GO:0002102)
0.2	1.0	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	1.8	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	4.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	25.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	8.2	GO:0044291	cell-cell contact zone(GO:0044291)
0.1	20.8	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	4.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	0.7	GO:0005955	calcineurin complex(GO:0005955)
0.1	20.9	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	2.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	1.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	68.2	GO:0070062	extracellular exosome(GO:0070062)
0.0	5.8	GO:0005911	cell-cell junction(GO:0005911)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.2	27.6	GO:0042134	rRNA primary transcript binding(GO:0042134)
7.9	55.1	GO:0061133	endopeptidase activator activity(GO:0061133)
5.7	22.7	GO:0016748	succinyltransferase activity(GO:0016748)
5.4	54.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
5.3	31.7	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
5.1	15.4	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
4.0	12.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
4.0	31.7	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
3.5	17.3	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
3.4	16.8	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
3.3	66.7	GO:0070628	proteasome binding(GO:0070628)
3.3	19.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
3.2	12.7	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.8	16.8	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
2.6	15.4	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
2.5	32.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
2.3	6.8	GO:0015230	FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
2.2	13.3	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
2.1	10.4	GO:0030348	syntaxin-3 binding(GO:0030348)
2.0	20.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
2.0	10.1	GO:0034046	poly(G) binding(GO:0034046)
1.9	23.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
1.9	42.3	GO:0042609	CD4 receptor binding(GO:0042609)
1.7	8.6	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
1.7	5.1	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.7	11.9	GO:0035614	snRNA stem-loop binding(GO:0035614)
1.7	5.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.6	12.6	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.6	47.1	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.5	7.7	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.4	15.7	GO:0016018	cyclosporin A binding(GO:0016018)
1.3	13.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
1.3	31.6	GO:0008327	methyl-CpG binding(GO:0008327)
1.3	33.9	GO:0008143	poly(A) binding(GO:0008143)
1.3	13.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
1.3	17.6	GO:0019870	potassium channel inhibitor activity(GO:0019870)
1.2	4.9	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
1.2	51.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
1.2	18.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
1.1	6.9	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.1	17.7	GO:0004526	ribonuclease P activity(GO:0004526)
1.0	9.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.0	5.0	GO:0070644	vitamin D response element binding(GO:0070644)
1.0	6.9	GO:0030620	U2 snRNA binding(GO:0030620)
1.0	13.4	GO:0008097	5S rRNA binding(GO:0008097)
1.0	11.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.9	11.3	GO:0031386	protein tag(GO:0031386)
0.8	12.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8	55.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.7	12.1	GO:0003680	AT DNA binding(GO:0003680)
0.7	19.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.7	14.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.6	57.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.6	7.6	GO:0089720	caspase binding(GO:0089720)
0.6	14.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	3.5	GO:0051022	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.5	24.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.5	21.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.4	107.0	GO:0051015	actin filament binding(GO:0051015)
0.4	6.2	GO:0030957	Tat protein binding(GO:0030957)
0.4	12.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4	7.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.3	5.8	GO:0001054	RNA polymerase I activity(GO:0001054)
0.3	20.9	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.3	10.3	GO:0036002	pre-mRNA binding(GO:0036002)
0.3	43.1	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3	7.5	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.2	35.1	GO:0044325	ion channel binding(GO:0044325)
0.2	21.8	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.2	3.0	GO:0097602	cullin family protein binding(GO:0097602)
0.1	4.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	1.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	21.5	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1	1.8	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	2.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	17.8	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	5.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	8.2	GO:0019003	GDP binding(GO:0019003)
0.1	14.2	GO:0051082	unfolded protein binding(GO:0051082)
0.1	3.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	4.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	7.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.1	5.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	16.0	GO:0030674	protein binding, bridging(GO:0030674)
0.1	4.3	GO:0051087	chaperone binding(GO:0051087)
0.1	4.9	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	2.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.0	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	7.9	GO:0003924	GTPase activity(GO:0003924)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	1.8	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	6.7	GO:0045296	cadherin binding(GO:0045296)
0.0	11.2	GO:0019900	kinase binding(GO:0019900)
0.0	4.1	GO:0008017	microtubule binding(GO:0008017)
0.0	1.5	GO:0017124	SH3 domain binding(GO:0017124)
0.0	2.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	23.2	PID S1P S1P4 PATHWAY	S1P4 pathway
1.0	53.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.6	29.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.6	36.4	PID BMP PATHWAY	BMP receptor signaling
0.5	17.6	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.5	27.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.5	11.4	PID ARF 3PATHWAY	Arf1 pathway
0.4	10.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.4	18.5	PID BARD1 PATHWAY	BARD1 signaling events
0.2	14.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	13.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.2	13.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	15.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	32.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	5.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	10.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	6.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	6.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	48.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.4	16.8	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
2.1	87.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
1.6	39.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.5	102.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
1.4	53.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.4	35.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
1.3	31.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
1.3	95.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.2	27.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.2	27.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.9	26.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.8	20.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.8	25.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8	17.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.8	18.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.8	22.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.7	44.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.7	84.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.7	18.0	REACTOME KINESINS	Genes involved in Kinesins
0.6	11.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.6	36.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.6	6.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.5	9.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5	71.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.4	15.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	5.8	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.3	4.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.3	27.8	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.3	4.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.3	3.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	7.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	4.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	8.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	4.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	5.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	5.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	14.1	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	1.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	10.7	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	8.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	6.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism