GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
SRF
|
ENSG00000112658.6 | serum response factor |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SRF | hg19_v2_chr6_+_43139037_43139094 | 0.09 | 1.8e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr20_+_35169885 | 122.26 |
ENST00000279022.2
ENST00000346786.2 |
MYL9
|
myosin, light chain 9, regulatory |
chr9_-_35691017 | 57.10 |
ENST00000378292.3
|
TPM2
|
tropomyosin 2 (beta) |
chr17_-_79481666 | 54.90 |
ENST00000575659.1
|
ACTG1
|
actin, gamma 1 |
chr2_+_74120094 | 53.06 |
ENST00000409731.3
ENST00000345517.3 ENST00000409918.1 ENST00000442912.1 ENST00000409624.1 |
ACTG2
|
actin, gamma 2, smooth muscle, enteric |
chr2_-_106015527 | 44.30 |
ENST00000344213.4
ENST00000358129.4 |
FHL2
|
four and a half LIM domains 2 |
chr2_-_106054952 | 44.10 |
ENST00000336660.5
ENST00000393352.3 ENST00000607522.1 |
FHL2
|
four and a half LIM domains 2 |
chr2_-_106015491 | 43.85 |
ENST00000408995.1
ENST00000393353.3 ENST00000322142.8 |
FHL2
|
four and a half LIM domains 2 |
chr11_+_117070037 | 33.42 |
ENST00000392951.4
ENST00000525531.1 ENST00000278968.6 |
TAGLN
|
transgelin |
chr19_-_45826125 | 32.24 |
ENST00000221476.3
|
CKM
|
creatine kinase, muscle |
chr10_-_90712520 | 32.11 |
ENST00000224784.6
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta |
chrX_-_153602991 | 31.40 |
ENST00000369850.3
ENST00000422373.1 |
FLNA
|
filamin A, alpha |
chr15_-_35088340 | 29.91 |
ENST00000290378.4
|
ACTC1
|
actin, alpha, cardiac muscle 1 |
chr1_+_223889285 | 26.94 |
ENST00000433674.2
|
CAPN2
|
calpain 2, (m/II) large subunit |
chr1_-_229569834 | 26.90 |
ENST00000366684.3
ENST00000366683.2 |
ACTA1
|
actin, alpha 1, skeletal muscle |
chr3_-_123339343 | 26.44 |
ENST00000578202.1
|
MYLK
|
myosin light chain kinase |
chr3_-_123339418 | 26.10 |
ENST00000583087.1
|
MYLK
|
myosin light chain kinase |
chr19_+_16178317 | 22.45 |
ENST00000344824.6
ENST00000538887.1 |
TPM4
|
tropomyosin 4 |
chr3_-_52486841 | 22.04 |
ENST00000496590.1
|
TNNC1
|
troponin C type 1 (slow) |
chr9_+_124088860 | 21.66 |
ENST00000373806.1
|
GSN
|
gelsolin |
chr7_-_94285472 | 21.07 |
ENST00000437425.2
ENST00000447873.1 ENST00000415788.2 |
SGCE
|
sarcoglycan, epsilon |
chr7_-_94285511 | 19.96 |
ENST00000265735.7
|
SGCE
|
sarcoglycan, epsilon |
chr12_+_75874580 | 19.80 |
ENST00000456650.3
|
GLIPR1
|
GLI pathogenesis-related 1 |
chr7_-_94285402 | 19.75 |
ENST00000428696.2
ENST00000445866.2 |
SGCE
|
sarcoglycan, epsilon |
chr8_+_97597148 | 19.37 |
ENST00000521590.1
|
SDC2
|
syndecan 2 |
chr12_+_75874460 | 19.18 |
ENST00000266659.3
|
GLIPR1
|
GLI pathogenesis-related 1 |
chr7_+_143078652 | 19.11 |
ENST00000354434.4
ENST00000449423.2 |
ZYX
|
zyxin |
chr10_+_75757863 | 18.66 |
ENST00000372755.3
ENST00000211998.4 ENST00000417648.2 |
VCL
|
vinculin |
chr14_+_75745477 | 18.01 |
ENST00000303562.4
ENST00000554617.1 ENST00000554212.1 ENST00000535987.1 ENST00000555242.1 |
FOS
|
FBJ murine osteosarcoma viral oncogene homolog |
chr22_-_36784035 | 17.99 |
ENST00000216181.5
|
MYH9
|
myosin, heavy chain 9, non-muscle |
chr15_+_74218787 | 17.37 |
ENST00000261921.7
|
LOXL1
|
lysyl oxidase-like 1 |
chr5_+_150404904 | 17.10 |
ENST00000521632.1
|
GPX3
|
glutathione peroxidase 3 (plasma) |
chr11_-_65667997 | 16.59 |
ENST00000312562.2
ENST00000534222.1 |
FOSL1
|
FOS-like antigen 1 |
chr15_+_96873921 | 16.52 |
ENST00000394166.3
|
NR2F2
|
nuclear receptor subfamily 2, group F, member 2 |
chr11_-_65667884 | 16.37 |
ENST00000448083.2
ENST00000531493.1 ENST00000532401.1 |
FOSL1
|
FOS-like antigen 1 |
chr17_+_42634844 | 15.97 |
ENST00000315323.3
|
FZD2
|
frizzled family receptor 2 |
chr3_-_99595037 | 15.47 |
ENST00000383694.2
|
FILIP1L
|
filamin A interacting protein 1-like |
chr7_-_107643674 | 14.48 |
ENST00000222399.6
|
LAMB1
|
laminin, beta 1 |
chr10_-_29923893 | 14.42 |
ENST00000355867.4
|
SVIL
|
supervillin |
chr3_+_187930719 | 14.38 |
ENST00000312675.4
|
LPP
|
LIM domain containing preferred translocation partner in lipoma |
chr3_-_46904918 | 14.14 |
ENST00000395869.1
|
MYL3
|
myosin, light chain 3, alkali; ventricular, skeletal, slow |
chr11_-_102323740 | 14.09 |
ENST00000398136.2
|
TMEM123
|
transmembrane protein 123 |
chr3_-_46904946 | 13.98 |
ENST00000292327.4
|
MYL3
|
myosin, light chain 3, alkali; ventricular, skeletal, slow |
chr2_-_161264385 | 13.86 |
ENST00000409972.1
|
RBMS1
|
RNA binding motif, single stranded interacting protein 1 |
chr11_-_102323489 | 13.73 |
ENST00000361236.3
|
TMEM123
|
transmembrane protein 123 |
chr6_+_151561506 | 13.37 |
ENST00000253332.1
|
AKAP12
|
A kinase (PRKA) anchor protein 12 |
chr1_-_89531041 | 13.24 |
ENST00000370473.4
|
GBP1
|
guanylate binding protein 1, interferon-inducible |
chr2_-_209118974 | 13.21 |
ENST00000415913.1
ENST00000415282.1 ENST00000446179.1 |
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble |
chr19_-_36247910 | 12.52 |
ENST00000587965.1
ENST00000004982.3 |
HSPB6
|
heat shock protein, alpha-crystallin-related, B6 |
chr3_-_99594948 | 12.02 |
ENST00000471562.1
ENST00000495625.2 |
FILIP1L
|
filamin A interacting protein 1-like |
chr12_-_50616382 | 11.91 |
ENST00000552783.1
|
LIMA1
|
LIM domain and actin binding 1 |
chr12_-_50616122 | 11.71 |
ENST00000552823.1
ENST00000552909.1 |
LIMA1
|
LIM domain and actin binding 1 |
chr6_+_151561085 | 11.63 |
ENST00000402676.2
|
AKAP12
|
A kinase (PRKA) anchor protein 12 |
chr4_-_10118469 | 11.27 |
ENST00000499869.2
|
WDR1
|
WD repeat domain 1 |
chr4_-_54930790 | 11.08 |
ENST00000263921.3
|
CHIC2
|
cysteine-rich hydrophobic domain 2 |
chr4_-_10118573 | 11.08 |
ENST00000382452.2
ENST00000382451.2 |
WDR1
|
WD repeat domain 1 |
chr19_+_1026298 | 10.71 |
ENST00000263097.4
|
CNN2
|
calponin 2 |
chr10_-_16859361 | 10.70 |
ENST00000377921.3
|
RSU1
|
Ras suppressor protein 1 |
chr19_+_45971246 | 10.55 |
ENST00000585836.1
ENST00000417353.2 ENST00000353609.3 ENST00000591858.1 ENST00000443841.2 ENST00000590335.1 |
FOSB
|
FBJ murine osteosarcoma viral oncogene homolog B |
chr10_-_16859442 | 10.44 |
ENST00000602389.1
ENST00000345264.5 |
RSU1
|
Ras suppressor protein 1 |
chr19_+_2476116 | 9.89 |
ENST00000215631.4
ENST00000587345.1 |
GADD45B
|
growth arrest and DNA-damage-inducible, beta |
chr19_+_1026566 | 9.28 |
ENST00000348419.3
ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1 |
CNN2
|
calponin 2 |
chr10_+_123922941 | 9.21 |
ENST00000360561.3
|
TACC2
|
transforming, acidic coiled-coil containing protein 2 |
chr1_+_11994715 | 9.15 |
ENST00000449038.1
ENST00000376369.3 ENST00000429000.2 ENST00000196061.4 |
PLOD1
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
chr14_+_74034310 | 8.90 |
ENST00000538782.1
|
ACOT2
|
acyl-CoA thioesterase 2 |
chr2_-_128432639 | 8.65 |
ENST00000545738.2
ENST00000355119.4 ENST00000409808.2 |
LIMS2
|
LIM and senescent cell antigen-like domains 2 |
chr22_-_36357671 | 8.60 |
ENST00000408983.2
|
RBFOX2
|
RNA binding protein, fox-1 homolog (C. elegans) 2 |
chr16_+_56965960 | 8.39 |
ENST00000439977.2
ENST00000344114.4 ENST00000300302.5 ENST00000379792.2 |
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
chr10_-_17659357 | 8.31 |
ENST00000326961.6
ENST00000361271.3 |
PTPLA
|
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A |
chr10_-_17659234 | 7.11 |
ENST00000466335.1
|
PTPLA
|
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A |
chr16_+_30383613 | 7.08 |
ENST00000568749.1
|
MYLPF
|
myosin light chain, phosphorylatable, fast skeletal muscle |
chr10_+_112257596 | 6.87 |
ENST00000369583.3
|
DUSP5
|
dual specificity phosphatase 5 |
chr18_-_3220106 | 6.64 |
ENST00000356443.4
ENST00000400569.3 |
MYOM1
|
myomesin 1 |
chr8_+_1993173 | 6.47 |
ENST00000523438.1
|
MYOM2
|
myomesin 2 |
chr7_-_44180884 | 6.38 |
ENST00000458240.1
ENST00000223364.3 |
MYL7
|
myosin, light chain 7, regulatory |
chr18_-_3219847 | 6.21 |
ENST00000261606.7
|
MYOM1
|
myomesin 1 |
chr1_-_89591749 | 6.18 |
ENST00000370466.3
|
GBP2
|
guanylate binding protein 2, interferon-inducible |
chr7_-_44180673 | 6.13 |
ENST00000457314.1
ENST00000447951.1 ENST00000431007.1 |
MYL7
|
myosin, light chain 7, regulatory |
chr8_+_1993152 | 6.11 |
ENST00000262113.4
|
MYOM2
|
myomesin 2 |
chr7_-_5570229 | 5.84 |
ENST00000331789.5
|
ACTB
|
actin, beta |
chr14_-_23877474 | 5.61 |
ENST00000405093.3
|
MYH6
|
myosin, heavy chain 6, cardiac muscle, alpha |
chr17_-_79479789 | 5.43 |
ENST00000571691.1
ENST00000571721.1 ENST00000573283.1 ENST00000575842.1 ENST00000575087.1 ENST00000570382.1 ENST00000331925.2 |
ACTG1
|
actin, gamma 1 |
chr18_-_54318353 | 5.01 |
ENST00000590954.1
ENST00000540155.1 |
TXNL1
|
thioredoxin-like 1 |
chr1_-_86043921 | 4.94 |
ENST00000535924.2
|
DDAH1
|
dimethylarginine dimethylaminohydrolase 1 |
chr7_-_27183263 | 4.93 |
ENST00000222726.3
|
HOXA5
|
homeobox A5 |
chr1_+_206858328 | 4.93 |
ENST00000367103.3
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2 |
chrX_-_11284095 | 4.89 |
ENST00000303025.6
ENST00000534860.1 |
ARHGAP6
|
Rho GTPase activating protein 6 |
chr5_-_169816638 | 4.79 |
ENST00000521859.1
ENST00000274629.4 |
KCNMB1
|
potassium large conductance calcium-activated channel, subfamily M, beta member 1 |
chr5_-_176923803 | 4.73 |
ENST00000506161.1
|
PDLIM7
|
PDZ and LIM domain 7 (enigma) |
chr16_-_11375179 | 4.50 |
ENST00000312511.3
|
PRM1
|
protamine 1 |
chr20_+_4702548 | 4.46 |
ENST00000305817.2
|
PRND
|
prion protein 2 (dublet) |
chr9_+_92219919 | 4.44 |
ENST00000252506.6
ENST00000375769.1 |
GADD45G
|
growth arrest and DNA-damage-inducible, gamma |
chr5_-_176923846 | 4.34 |
ENST00000506537.1
|
PDLIM7
|
PDZ and LIM domain 7 (enigma) |
chr3_+_9834179 | 4.20 |
ENST00000498623.2
|
ARPC4
|
actin related protein 2/3 complex, subunit 4, 20kDa |
chr1_-_208084729 | 3.92 |
ENST00000310833.7
ENST00000356522.4 |
CD34
|
CD34 molecule |
chr17_-_46671323 | 3.52 |
ENST00000239151.5
|
HOXB5
|
homeobox B5 |
chr3_-_185641681 | 3.48 |
ENST00000259043.7
|
TRA2B
|
transformer 2 beta homolog (Drosophila) |
chr15_-_55581954 | 3.12 |
ENST00000336787.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
chr4_+_87928140 | 3.05 |
ENST00000307808.6
|
AFF1
|
AF4/FMR2 family, member 1 |
chr12_+_52445191 | 3.02 |
ENST00000243050.1
ENST00000394825.1 ENST00000550763.1 ENST00000394824.2 ENST00000548232.1 ENST00000562373.1 |
NR4A1
|
nuclear receptor subfamily 4, group A, member 1 |
chr16_+_30077055 | 2.52 |
ENST00000564595.2
ENST00000569798.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
chr11_-_65626753 | 2.50 |
ENST00000526975.1
ENST00000531413.1 |
CFL1
|
cofilin 1 (non-muscle) |
chr11_-_47374246 | 2.50 |
ENST00000545968.1
ENST00000399249.2 ENST00000256993.4 |
MYBPC3
|
myosin binding protein C, cardiac |
chr5_+_92919043 | 2.44 |
ENST00000327111.3
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1 |
chr10_+_31610064 | 2.39 |
ENST00000446923.2
ENST00000559476.1 |
ZEB1
|
zinc finger E-box binding homeobox 1 |
chr16_+_30077098 | 2.29 |
ENST00000395240.3
ENST00000566846.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
chr7_+_94285637 | 2.05 |
ENST00000482108.1
ENST00000488574.1 |
PEG10
|
paternally expressed 10 |
chr2_-_208031943 | 1.70 |
ENST00000421199.1
ENST00000457962.1 |
KLF7
|
Kruppel-like factor 7 (ubiquitous) |
chr11_+_34073195 | 1.56 |
ENST00000341394.4
|
CAPRIN1
|
cell cycle associated protein 1 |
chr6_-_99797522 | 1.55 |
ENST00000389677.5
|
FAXC
|
failed axon connections homolog (Drosophila) |
chr19_-_17356697 | 1.44 |
ENST00000291442.3
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6 |
chr6_-_16761678 | 1.29 |
ENST00000244769.4
ENST00000436367.1 |
ATXN1
|
ataxin 1 |
chr20_-_62258394 | 1.26 |
ENST00000370077.1
|
GMEB2
|
glucocorticoid modulatory element binding protein 2 |
chr6_-_111804905 | 1.08 |
ENST00000358835.3
ENST00000435970.1 |
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
chr12_+_59989918 | 1.04 |
ENST00000547379.1
ENST00000549465.1 |
SLC16A7
|
solute carrier family 16 (monocarboxylate transporter), member 7 |
chr3_+_9834227 | 1.03 |
ENST00000287613.7
ENST00000397261.3 |
ARPC4
|
actin related protein 2/3 complex, subunit 4, 20kDa |
chr17_+_7487146 | 0.74 |
ENST00000396501.4
ENST00000584378.1 ENST00000423172.2 ENST00000579445.1 ENST00000585217.1 ENST00000581380.1 |
MPDU1
|
mannose-P-dolichol utilization defect 1 |
chr5_-_33892046 | 0.64 |
ENST00000352040.3
|
ADAMTS12
|
ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
chr1_+_47881744 | 0.63 |
ENST00000335071.2
|
FOXE3
|
forkhead box E3 |
chr5_-_33892204 | 0.43 |
ENST00000504830.1
|
ADAMTS12
|
ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
chr5_-_179050660 | 0.39 |
ENST00000519056.1
ENST00000506721.1 ENST00000503105.1 ENST00000504348.1 ENST00000508103.1 ENST00000510431.1 ENST00000515158.1 ENST00000393432.4 ENST00000442819.2 |
HNRNPH1
|
heterogeneous nuclear ribonucleoprotein H1 (H) |
chr10_+_88428206 | 0.21 |
ENST00000429277.2
ENST00000458213.2 ENST00000352360.5 |
LDB3
|
LIM domain binding 3 |
chr4_+_87928413 | 0.20 |
ENST00000544085.1
|
AFF1
|
AF4/FMR2 family, member 1 |
chr2_-_231989808 | 0.17 |
ENST00000258400.3
|
HTR2B
|
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
chr11_-_71823796 | 0.16 |
ENST00000545680.1
ENST00000543587.1 ENST00000538393.1 ENST00000535234.1 ENST00000227618.4 ENST00000535503.1 |
ANAPC15
|
anaphase promoting complex subunit 15 |
chr17_-_4871085 | 0.14 |
ENST00000575142.1
ENST00000206020.3 |
SPAG7
|
sperm associated antigen 7 |
chr2_-_161056762 | 0.13 |
ENST00000428609.2
ENST00000409967.2 |
ITGB6
|
integrin, beta 6 |
chr5_+_40679584 | 0.09 |
ENST00000302472.3
|
PTGER4
|
prostaglandin E receptor 4 (subtype EP4) |
chr11_-_71823266 | 0.01 |
ENST00000538919.1
ENST00000539395.1 ENST00000542531.1 |
ANAPC15
|
anaphase promoting complex subunit 15 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
26.5 | 132.3 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
23.7 | 142.0 | GO:0090131 | mesenchyme migration(GO:0090131) |
6.6 | 39.7 | GO:1903921 | protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
6.6 | 52.5 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
5.7 | 17.1 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
5.6 | 22.3 | GO:0016334 | morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247) |
5.5 | 22.0 | GO:0032972 | diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972) |
5.5 | 33.0 | GO:0007296 | vitellogenesis(GO:0007296) |
5.2 | 31.4 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
4.4 | 13.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
4.1 | 16.5 | GO:0060849 | radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
3.6 | 14.5 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
3.4 | 17.2 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
3.2 | 25.4 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
3.1 | 9.2 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
2.9 | 32.2 | GO:0006600 | creatine metabolic process(GO:0006600) |
2.8 | 19.4 | GO:0008218 | bioluminescence(GO:0008218) |
2.5 | 2.5 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
2.3 | 18.0 | GO:0001661 | conditioned taste aversion(GO:0001661) |
2.2 | 207.1 | GO:0070527 | platelet aggregation(GO:0070527) |
2.0 | 16.0 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
1.7 | 27.8 | GO:0045793 | positive regulation of cell size(GO:0045793) |
1.7 | 8.6 | GO:0060318 | regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318) |
1.7 | 25.0 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
1.6 | 4.9 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
1.6 | 4.8 | GO:1903413 | cellular response to bile acid(GO:1903413) |
1.5 | 111.7 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
0.9 | 17.8 | GO:0016540 | protein autoprocessing(GO:0016540) |
0.9 | 3.5 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.9 | 8.6 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.8 | 2.4 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.6 | 14.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.6 | 4.9 | GO:0044351 | macropinocytosis(GO:0044351) |
0.6 | 8.4 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.5 | 3.1 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
0.5 | 10.6 | GO:0051412 | response to corticosterone(GO:0051412) |
0.5 | 12.5 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
0.4 | 6.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.4 | 23.6 | GO:0031529 | ruffle organization(GO:0031529) |
0.4 | 4.9 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
0.3 | 3.0 | GO:0061469 | response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
0.3 | 0.6 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.3 | 14.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.3 | 15.7 | GO:0035904 | aorta development(GO:0035904) |
0.3 | 4.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.3 | 4.5 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
0.2 | 13.6 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
0.2 | 20.0 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
0.2 | 75.1 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
0.2 | 8.9 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.2 | 11.1 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
0.1 | 9.1 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
0.1 | 4.5 | GO:0030261 | chromosome condensation(GO:0030261) |
0.1 | 28.3 | GO:0007517 | muscle organ development(GO:0007517) |
0.1 | 9.2 | GO:0021987 | cerebral cortex development(GO:0021987) |
0.1 | 1.4 | GO:0050961 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
0.1 | 5.0 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.1 | 2.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.1 | 1.6 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.1 | 6.2 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
0.1 | 23.1 | GO:0019216 | regulation of lipid metabolic process(GO:0019216) |
0.1 | 1.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.0 | 3.5 | GO:0048704 | embryonic skeletal system morphogenesis(GO:0048704) |
0.0 | 0.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 10.6 | GO:0006936 | muscle contraction(GO:0006936) |
0.0 | 1.7 | GO:1903845 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
0.0 | 0.1 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
0.0 | 2.4 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 1.7 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.0 | 12.7 | GO:0007155 | cell adhesion(GO:0007155) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.5 | 31.4 | GO:0031523 | Myb complex(GO:0031523) |
10.5 | 52.3 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
8.8 | 53.1 | GO:0032982 | myosin filament(GO:0032982) |
8.0 | 32.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
7.6 | 60.8 | GO:0016012 | sarcoglycan complex(GO:0016012) |
6.0 | 18.0 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
5.3 | 189.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
5.1 | 66.2 | GO:0097433 | dense body(GO:0097433) |
4.8 | 14.5 | GO:0005607 | laminin-2 complex(GO:0005607) |
4.2 | 79.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
3.7 | 22.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
3.4 | 137.1 | GO:0031430 | M band(GO:0031430) |
2.3 | 18.0 | GO:0035976 | AP1 complex(GO:0035976) |
2.1 | 14.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
1.6 | 151.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
1.6 | 18.7 | GO:0005916 | fascia adherens(GO:0005916) |
1.4 | 21.7 | GO:0030478 | actin cap(GO:0030478) |
1.4 | 8.4 | GO:1990037 | Lewy body core(GO:1990037) |
1.1 | 17.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.7 | 12.5 | GO:0031672 | A band(GO:0031672) |
0.5 | 39.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
0.4 | 9.2 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.3 | 33.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.3 | 3.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.2 | 16.0 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.2 | 13.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.2 | 3.9 | GO:0046930 | pore complex(GO:0046930) |
0.2 | 19.4 | GO:0005796 | Golgi lumen(GO:0005796) |
0.2 | 17.4 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 11.1 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
0.1 | 0.7 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
0.1 | 2.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 27.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.1 | 53.5 | GO:0005925 | focal adhesion(GO:0005925) |
0.1 | 4.5 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 1.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.1 | 3.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.1 | 4.9 | GO:0005884 | actin filament(GO:0005884) |
0.1 | 5.0 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 3.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 4.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 2.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
0.0 | 1.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 18.0 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 3.5 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 1.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 7.6 | GO:0005815 | microtubule organizing center(GO:0005815) |
0.0 | 10.9 | GO:0005615 | extracellular space(GO:0005615) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.5 | 52.5 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
9.6 | 152.9 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
7.8 | 31.4 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
4.4 | 13.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
4.0 | 32.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
3.1 | 9.2 | GO:0033823 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
2.7 | 21.7 | GO:0045159 | myosin II binding(GO:0045159) |
2.0 | 22.0 | GO:0031013 | troponin I binding(GO:0031013) |
1.7 | 132.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
1.7 | 18.7 | GO:0045294 | alpha-catenin binding(GO:0045294) |
1.6 | 25.0 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
1.6 | 17.1 | GO:0008430 | selenium binding(GO:0008430) |
1.2 | 2.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
1.2 | 112.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
1.1 | 17.4 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
1.1 | 23.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
1.0 | 4.9 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.9 | 59.9 | GO:0017022 | myosin binding(GO:0017022) |
0.8 | 8.9 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.7 | 5.0 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
0.7 | 16.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.6 | 5.8 | GO:0030957 | Tat protein binding(GO:0030957) |
0.6 | 23.6 | GO:0003785 | actin monomer binding(GO:0003785) |
0.5 | 17.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.5 | 13.2 | GO:0030507 | spectrin binding(GO:0030507) |
0.5 | 12.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.4 | 4.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.4 | 62.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.4 | 16.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.4 | 3.9 | GO:0043199 | sulfate binding(GO:0043199) |
0.4 | 18.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.4 | 54.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.3 | 4.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.3 | 1.3 | GO:0034046 | poly(G) binding(GO:0034046) |
0.2 | 19.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.2 | 4.8 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 14.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 2.4 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 3.5 | GO:0070717 | poly-purine tract binding(GO:0070717) |
0.1 | 3.0 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.1 | 13.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.1 | 1.4 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.1 | 9.2 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
0.1 | 42.5 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.1 | 3.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 1.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 4.5 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 15.4 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 4.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 1.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 8.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 58.8 | GO:0005524 | ATP binding(GO:0005524) |
0.0 | 2.6 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.2 | GO:0043176 | amine binding(GO:0043176) serotonin binding(GO:0051378) |
0.0 | 15.7 | GO:0060089 | receptor activity(GO:0004872) molecular transducer activity(GO:0060089) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.8 | 132.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
3.2 | 186.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
1.7 | 143.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
1.1 | 61.9 | PID RHOA PATHWAY | RhoA signaling pathway |
0.7 | 38.0 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.6 | 14.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.6 | 33.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.5 | 21.7 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
0.5 | 16.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.5 | 9.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.5 | 19.4 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.4 | 14.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.3 | 52.8 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
0.3 | 17.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
0.3 | 30.5 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
0.2 | 6.9 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
0.2 | 16.5 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
0.2 | 4.9 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.2 | 14.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.1 | 7.1 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
0.1 | 7.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
0.1 | 3.0 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
0.1 | 4.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.1 | 15.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 4.8 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 3.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 2.4 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 2.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.6 | 358.2 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
1.2 | 171.2 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
1.1 | 54.2 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
0.7 | 21.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.7 | 19.4 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
0.7 | 21.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.5 | 4.9 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
0.5 | 18.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.4 | 13.2 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.4 | 12.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.4 | 7.8 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.3 | 8.4 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
0.2 | 19.4 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.1 | 5.8 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.1 | 9.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
0.1 | 14.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.1 | 16.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.1 | 3.1 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 4.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
0.1 | 26.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.1 | 6.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 10.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 3.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 4.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |