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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for SRY

Z-value: 1.02

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.6 sex determining region Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg19_v2_chrY_-_2655644_26557400.425.7e-11Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39509163 52.69 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr3_+_39509070 47.78 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr9_+_139874683 24.07 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr14_-_60097297 21.93 ENST00000395090.1
RTN1
reticulon 1
chr5_-_146435694 17.05 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr3_+_189507460 16.55 ENST00000434928.1
TP63
tumor protein p63
chr10_+_11206925 15.21 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr5_-_146435572 15.18 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_146435501 15.11 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr20_-_35492048 14.81 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr8_+_85095497 14.57 ENST00000522455.1
ENST00000521695.1
RALYL
RALY RNA binding protein-like
chr11_+_112832090 14.56 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr13_-_41240717 14.39 ENST00000379561.5
FOXO1
forkhead box O1
chr2_-_2334888 14.16 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr6_-_32557610 13.79 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr5_-_131132614 13.60 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr6_-_152489484 13.27 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_-_99393208 13.26 ENST00000307450.6
MORN4
MORN repeat containing 4
chr8_+_85095553 13.05 ENST00000521268.1
RALYL
RALY RNA binding protein-like
chr21_-_32931290 13.03 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr10_+_70847852 12.92 ENST00000242465.3
SRGN
serglycin
chr8_+_85095769 12.92 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr2_-_71454185 12.89 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr18_-_52989217 12.89 ENST00000570287.2
TCF4
transcription factor 4
chr1_-_156217822 12.82 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chr2_+_30569506 12.78 ENST00000421976.2
AC109642.1
AC109642.1
chr1_-_156217829 12.54 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6
progestin and adipoQ receptor family member VI
chr1_-_156217875 12.47 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr17_-_17875688 11.91 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr18_-_53257027 11.85 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr18_-_53303123 11.49 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr10_+_11207438 11.38 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chr14_+_37126765 11.33 ENST00000402703.2
PAX9
paired box 9
chr2_-_157198860 10.83 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr5_-_146461027 10.45 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr16_+_6069586 9.97 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_27070964 9.78 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr17_+_17876127 9.62 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr22_+_19710468 9.61 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr4_+_165675269 9.16 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr16_+_2588012 9.07 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr18_+_72201829 9.07 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr16_-_4852915 9.06 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr10_+_111967345 9.06 ENST00000332674.5
ENST00000453116.1
MXI1
MAX interactor 1, dimerization protein
chr5_-_11589131 9.05 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr10_+_111985713 9.05 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr11_+_128563652 8.58 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_-_177134024 8.52 ENST00000367654.3
ASTN1
astrotactin 1
chr11_+_131781290 8.51 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr9_-_123476612 8.04 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr1_+_50574585 8.01 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr16_+_2587998 7.97 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr9_-_123476719 7.79 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr3_-_28390581 7.55 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr16_-_68482440 7.54 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr6_+_126070726 7.50 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr5_+_66254698 7.46 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_84499081 7.36 ENST00000276123.3
ZNF711
zinc finger protein 711
chr16_+_2587965 7.11 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr20_-_3762087 7.00 ENST00000379756.3
SPEF1
sperm flagellar 1
chr12_-_10251576 6.99 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr15_-_86338134 6.96 ENST00000337975.5
KLHL25
kelch-like family member 25
chr11_+_128563948 6.91 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chrX_+_84499038 6.85 ENST00000373165.3
ZNF711
zinc finger protein 711
chr16_+_6069072 6.84 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_131132658 6.82 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr1_-_151119087 6.73 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr18_-_52969844 6.73 ENST00000561831.3
TCF4
transcription factor 4
chr1_+_84630053 6.72 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_147374915 6.72 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr10_-_62149433 6.66 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_103851712 6.65 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr15_-_86338100 6.65 ENST00000536947.1
KLHL25
kelch-like family member 25
chr11_+_112832202 6.63 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr11_+_126225529 6.61 ENST00000227495.6
ENST00000444328.2
ENST00000356132.4
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr10_-_62332357 6.58 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_106959631 6.58 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr4_-_76598326 6.55 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr17_+_76311791 6.48 ENST00000586321.1
AC061992.2
AC061992.2
chr14_-_92413727 6.29 ENST00000267620.10
FBLN5
fibulin 5
chr1_-_177133818 6.26 ENST00000424564.2
ENST00000361833.2
ASTN1
astrotactin 1
chr11_-_82708519 6.25 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr1_-_217311090 6.15 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr1_+_50571949 6.11 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr9_-_23826298 6.00 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr18_+_46065483 5.81 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr2_-_220042825 5.71 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr15_-_88799948 5.68 ENST00000394480.2
NTRK3
neurotrophic tyrosine kinase, receptor, type 3
chr14_+_91580732 5.67 ENST00000519019.1
ENST00000523816.1
ENST00000517518.1
C14orf159
chromosome 14 open reading frame 159
chr7_+_29519662 5.62 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
CHN2
chimerin 2
chr5_+_140248518 5.51 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr11_-_35440796 5.51 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_61900762 5.49 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr14_+_91580777 5.44 ENST00000525393.2
ENST00000428926.2
ENST00000517362.1
C14orf159
chromosome 14 open reading frame 159
chr15_-_34610962 5.42 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_-_10251603 5.40 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr11_-_35441597 5.30 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_29519486 5.19 ENST00000409041.4
CHN2
chimerin 2
chr8_+_24151553 5.13 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM28
ADAM metallopeptidase domain 28
chr13_+_113633620 5.10 ENST00000421756.1
ENST00000375601.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chrX_+_107288239 5.07 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr6_+_72596604 5.05 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1
regulating synaptic membrane exocytosis 1
chr18_-_52989525 4.94 ENST00000457482.3
TCF4
transcription factor 4
chr5_-_24645078 4.87 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr14_+_91580708 4.85 ENST00000518868.1
C14orf159
chromosome 14 open reading frame 159
chr1_-_57045228 4.83 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_66797687 4.83 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr16_-_15736881 4.67 ENST00000540441.2
KIAA0430
KIAA0430
chr14_+_91580357 4.58 ENST00000298858.4
ENST00000521081.1
ENST00000520328.1
ENST00000256324.10
ENST00000524232.1
ENST00000522170.1
ENST00000519950.1
ENST00000523879.1
ENST00000521077.2
ENST00000518665.2
C14orf159
chromosome 14 open reading frame 159
chr9_-_23825956 4.49 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr2_+_86947296 4.40 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr1_+_43855560 4.39 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr8_-_72274095 4.33 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_163148780 4.32 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr3_-_62358690 4.27 ENST00000475839.1
FEZF2
FEZ family zinc finger 2
chr2_+_226265364 4.26 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr17_-_56406117 4.26 ENST00000268893.6
ENST00000355701.3
BZRAP1
benzodiazepine receptor (peripheral) associated protein 1
chr14_+_91581011 4.25 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr12_+_94542459 4.23 ENST00000258526.4
PLXNC1
plexin C1
chr14_-_89883412 4.20 ENST00000557258.1
FOXN3
forkhead box N3
chr4_+_118955500 4.15 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr5_-_147162263 4.04 ENST00000333010.6
ENST00000265272.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr14_+_58894103 4.02 ENST00000354386.6
ENST00000556134.1
KIAA0586
KIAA0586
chr21_-_19191703 4.00 ENST00000284881.4
ENST00000400559.3
ENST00000400558.3
C21orf91
chromosome 21 open reading frame 91
chr6_+_163148973 3.94 ENST00000366888.2
PACRG
PARK2 co-regulated
chr13_-_74708372 3.92 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr8_-_93115445 3.88 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_55413721 3.82 ENST00000242994.3
NEUROD4
neuronal differentiation 4
chr11_+_128562372 3.82 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr17_-_67138015 3.78 ENST00000284425.2
ENST00000590645.1
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr1_+_84630645 3.76 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_35441524 3.76 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_58894141 3.76 ENST00000423743.3
KIAA0586
KIAA0586
chr18_+_11851383 3.71 ENST00000526991.2
CHMP1B
charged multivesicular body protein 1B
chr6_+_139094657 3.70 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr12_-_102591604 3.69 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr2_-_166060552 3.68 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr1_-_115053781 3.66 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr9_+_8858102 3.64 ENST00000447950.1
ENST00000430766.1
RP11-75C9.1
RP11-75C9.1
chr22_+_40297105 3.64 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chr17_-_40428359 3.61 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr4_-_109089573 3.60 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr4_+_39408470 3.58 ENST00000257408.4
KLB
klotho beta
chrX_+_107288197 3.51 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr8_-_145688231 3.49 ENST00000530374.1
CYHR1
cysteine/histidine-rich 1
chr1_-_160231451 3.44 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr8_-_87755878 3.41 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr13_-_46716969 3.36 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_178253993 3.33 ENST00000420517.2
ENST00000452583.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_+_99079008 3.32 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr14_-_92414055 3.30 ENST00000342058.4
FBLN5
fibulin 5
chr14_-_23288930 3.25 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_1832902 3.25 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr1_-_40367530 3.20 ENST00000372816.2
ENST00000372815.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr4_+_71263599 3.16 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr3_+_189507523 3.13 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr4_+_170581213 3.13 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_-_208030647 3.09 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr16_-_4323015 2.88 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr16_+_28858004 2.86 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr22_+_40297079 2.81 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chr12_+_31477250 2.75 ENST00000313737.4
AC024940.1
AC024940.1
chr2_-_166060571 2.71 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr19_-_46272462 2.71 ENST00000317578.6
SIX5
SIX homeobox 5
chr2_+_162101247 2.70 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr22_-_31741757 2.60 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr11_-_82708435 2.55 ENST00000525117.1
ENST00000532548.1
RAB30
RAB30, member RAS oncogene family
chr2_+_220042933 2.46 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr9_+_27109133 2.45 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr3_+_89156799 2.43 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr11_+_67007518 2.41 ENST00000530342.1
ENST00000308783.5
KDM2A
lysine (K)-specific demethylase 2A
chr21_-_19775973 2.40 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr5_-_59481406 2.39 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_24151620 2.33 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr6_+_108882069 2.23 ENST00000406360.1
FOXO3
forkhead box O3
chr12_-_95611149 2.22 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr6_+_122720681 2.21 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chrX_+_15525426 2.21 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr7_+_142985308 2.18 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr4_-_68749745 2.13 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr9_-_124989804 2.13 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr5_+_140201183 2.12 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr14_+_58894706 2.11 ENST00000261244.5
KIAA0586
KIAA0586
chr19_-_47734448 2.03 ENST00000439096.2
BBC3
BCL2 binding component 3
chr6_+_31082603 2.00 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr12_+_130646999 1.96 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr4_+_71588372 1.96 ENST00000536664.1
RUFY3
RUN and FYVE domain containing 3
chr5_+_140743859 1.96 ENST00000518069.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr13_-_99910673 1.95 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr19_-_46272106 1.95 ENST00000560168.1
SIX5
SIX homeobox 5
chr3_-_33700933 1.94 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr9_-_37465396 1.90 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr13_+_22245522 1.88 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr4_-_109090106 1.67 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr7_+_106505912 1.66 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr10_-_99094458 1.63 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_193155729 1.57 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr6_-_161085291 1.47 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr18_-_64271363 1.35 ENST00000262150.2
CDH19
cadherin 19, type 2
chr5_-_147162078 1.34 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 100.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
5.1 20.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
4.9 19.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
4.7 18.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.3 12.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
3.6 10.8 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
2.9 14.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
2.8 13.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
2.5 57.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
2.5 7.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
2.4 24.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.2 13.0 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
2.1 10.5 GO:0097338 response to clozapine(GO:0097338)
1.9 5.7 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
1.8 14.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.3 24.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.3 13.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.1 5.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.1 5.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.9 6.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.9 14.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.9 3.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.9 19.3 GO:0035855 megakaryocyte development(GO:0035855)
0.9 3.5 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.8 2.5 GO:0032252 secretory granule localization(GO:0032252)
0.8 6.6 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8 9.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.8 3.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.8 7.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 2.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.7 4.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.7 2.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.7 18.6 GO:0048665 neuron fate specification(GO:0048665)
0.7 3.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 26.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 4.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.6 3.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.6 7.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 24.8 GO:0006536 glutamate metabolic process(GO:0006536)
0.5 3.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.5 14.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 0.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.5 12.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.5 8.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 3.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.4 1.3 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.4 11.3 GO:0060325 face morphogenesis(GO:0060325)
0.4 9.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 2.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 4.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.4 12.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.4 3.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 16.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.4 2.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.3 2.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.3 5.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 3.7 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.3 2.0 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.3 2.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 6.6 GO:0097503 sialylation(GO:0097503)
0.2 4.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 1.9 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 5.0 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.2 2.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 16.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 9.7 GO:0019228 neuronal action potential(GO:0019228)
0.2 2.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 11.9 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 0.9 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 2.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 1.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 3.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 10.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 3.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 9.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 7.5 GO:0097028 dendritic cell differentiation(GO:0097028)
0.1 20.4 GO:0046718 viral entry into host cell(GO:0046718)
0.1 3.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 4.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 20.6 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 29.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.8 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 2.7 GO:0008038 neuron recognition(GO:0008038)
0.1 3.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 14.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 9.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 4.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 1.5 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 2.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 3.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 3.8 GO:0006952 defense response(GO:0006952)
0.0 1.0 GO:0036499 PERK-mediated unfolded protein response(GO:0036499)
0.0 2.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 3.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.5 GO:0007030 Golgi organization(GO:0007030)
0.0 3.9 GO:0007286 spermatid development(GO:0007286)
0.0 7.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 4.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 5.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.9 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.1 GO:0006953 acute-phase response(GO:0006953)
0.0 3.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 2.6 GO:0030217 T cell differentiation(GO:0030217)
0.0 3.8 GO:0006869 lipid transport(GO:0006869)
0.0 2.5 GO:0007411 axon guidance(GO:0007411)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 57.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.5 4.4 GO:0034657 GID complex(GO:0034657)
1.1 18.7 GO:0043194 axon initial segment(GO:0043194)
1.1 7.5 GO:0000137 Golgi cis cisterna(GO:0000137)
1.0 13.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.0 9.8 GO:0071953 elastic fiber(GO:0071953)
0.8 2.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.7 4.4 GO:1990130 Iml1 complex(GO:1990130)
0.7 13.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 12.9 GO:0042588 zymogen granule(GO:0042588)
0.6 67.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.6 13.0 GO:0044295 axonal growth cone(GO:0044295)
0.5 10.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 5.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.5 14.6 GO:0030673 axolemma(GO:0030673)
0.5 6.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 43.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.4 6.7 GO:0005922 connexon complex(GO:0005922)
0.3 3.1 GO:0045180 basal cortex(GO:0045180)
0.3 3.7 GO:0000815 ESCRT III complex(GO:0000815)
0.3 41.4 GO:0043204 perikaryon(GO:0043204)
0.2 50.6 GO:0032993 protein-DNA complex(GO:0032993)
0.2 3.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 9.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 3.9 GO:0097225 sperm midpiece(GO:0097225)
0.2 3.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 13.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 26.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 15.4 GO:0031985 Golgi cisterna(GO:0031985)
0.1 5.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 10.6 GO:0005604 basement membrane(GO:0005604)
0.1 14.5 GO:0005802 trans-Golgi network(GO:0005802)
0.1 7.0 GO:0031514 motile cilium(GO:0031514)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 9.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 22.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 67.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 4.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 51.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.2 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 100.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
8.0 24.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
6.0 24.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
5.1 20.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
5.0 24.8 GO:0047820 D-glutamate cyclase activity(GO:0047820)
3.7 47.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.1 14.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.9 7.5 GO:0035939 microsatellite binding(GO:0035939)
1.7 6.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
1.5 19.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.9 3.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.8 7.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 6.6 GO:0043426 MRF binding(GO:0043426)
0.7 4.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.7 10.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.7 1.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.6 12.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.6 57.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.6 7.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 26.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.6 4.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.6 14.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.5 13.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 3.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 5.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 13.3 GO:0005521 lamin binding(GO:0005521)
0.5 3.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.5 12.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.4 6.7 GO:0005243 gap junction channel activity(GO:0005243)
0.4 13.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 43.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.4 18.7 GO:0030507 spectrin binding(GO:0030507)
0.3 9.1 GO:0016805 dipeptidase activity(GO:0016805)
0.3 2.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 3.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 6.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 1.8 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 4.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 2.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 0.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 20.4 GO:0001618 virus receptor activity(GO:0001618)
0.2 7.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 11.9 GO:0030276 clathrin binding(GO:0030276)
0.1 17.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 3.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 3.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 11.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 3.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 28.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 3.7 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 16.1 GO:0046983 protein dimerization activity(GO:0046983)
0.1 3.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 3.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 4.4 GO:0005518 collagen binding(GO:0005518)
0.1 14.0 GO:0008017 microtubule binding(GO:0008017)
0.1 2.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 3.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 4.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 5.1 GO:0044325 ion channel binding(GO:0044325)
0.0 9.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 7.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.0 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 3.8 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 2.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 23.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6 37.4 PID ATR PATHWAY ATR signaling pathway
0.5 13.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.4 15.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.4 14.1 PID IL3 PATHWAY IL3-mediated signaling events
0.4 44.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.3 21.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 17.3 PID FGF PATHWAY FGF signaling pathway
0.3 13.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 6.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 13.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 10.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 27.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 4.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 11.9 PID P73PATHWAY p73 transcription factor network
0.1 8.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 5.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 4.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 47.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.8 26.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.6 13.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6 9.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.6 18.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 11.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 9.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 6.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 10.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 20.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.3 19.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 5.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 6.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 6.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 3.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 7.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 4.5 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.2 15.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 7.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 9.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 3.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 7.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits