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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for STAT4

Z-value: 0.94

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192016316_1920163250.401.0e-09Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_107288239 18.46 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_107288197 16.77 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr4_+_158141806 15.34 ENST00000393815.2
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr8_-_120685608 15.28 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_158141843 14.87 ENST00000509417.1
ENST00000296526.7
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr4_+_158141899 14.75 ENST00000264426.9
ENST00000506284.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr17_-_34207295 12.15 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_+_32407619 11.69 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_-_15469006 11.04 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr3_+_122296465 10.93 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr14_-_21490958 10.39 ENST00000554104.1
NDRG2
NDRG family member 2
chr19_+_42746927 9.92 ENST00000378108.1
AC006486.1
AC006486.1
chr7_+_55980331 9.84 ENST00000429591.2
ZNF713
zinc finger protein 713
chr8_-_27468842 9.77 ENST00000523500.1
CLU
clusterin
chr14_-_21270561 9.60 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr2_+_68962014 9.59 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr19_+_39881951 9.39 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr19_+_35225060 9.35 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr3_+_15468862 9.25 ENST00000396842.2
EAF1
ELL associated factor 1
chr4_+_41258786 9.22 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr14_-_21490653 9.13 ENST00000449431.2
NDRG2
NDRG family member 2
chr11_-_64490634 9.03 ENST00000377559.3
ENST00000265459.6
NRXN2
neurexin 2
chr5_-_140013275 8.85 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr14_-_21490590 8.79 ENST00000557633.1
NDRG2
NDRG family member 2
chr19_+_35168567 8.59 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302
chr19_+_35168633 8.40 ENST00000505365.2
ZNF302
zinc finger protein 302
chr14_-_21490417 8.19 ENST00000556366.1
NDRG2
NDRG family member 2
chr2_+_68961934 7.96 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68961905 7.80 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr1_+_117297007 7.48 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chrX_-_65253506 7.07 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr1_+_233086326 7.03 ENST00000366628.5
ENST00000366627.4
NTPCR
nucleoside-triphosphatase, cancer-related
chr3_-_114866084 6.82 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr15_-_75660919 6.71 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1
mannosidase, alpha, class 2C, member 1
chr5_-_39274617 6.58 ENST00000510188.1
FYB
FYN binding protein
chr5_+_140753444 6.22 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr18_+_61144160 6.03 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_-_57678772 5.86 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr20_-_18774614 5.70 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr8_-_27469196 5.62 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr16_+_58283814 5.54 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr1_-_9811600 5.53 ENST00000435891.1
CLSTN1
calsyntenin 1
chr11_+_118175596 5.46 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_+_140261703 5.45 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr13_-_41240717 5.45 ENST00000379561.5
FOXO1
forkhead box O1
chr14_+_24630465 5.44 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr13_-_45915221 5.15 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr19_-_59084647 5.08 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr19_-_51875894 4.95 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chrX_-_137793826 4.91 ENST00000315930.6
FGF13
fibroblast growth factor 13
chr11_+_118175132 4.87 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_-_16509101 4.76 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr10_-_6622201 4.46 ENST00000539722.1
ENST00000397176.2
PRKCQ
protein kinase C, theta
chr19_+_10197463 4.45 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr1_+_17906970 4.45 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_+_58138800 4.38 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31
tetraspanin 31
chr12_+_56324756 4.35 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr5_-_111093406 4.30 ENST00000379671.3
NREP
neuronal regeneration related protein
chr14_-_25103472 4.20 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr12_+_58138664 4.06 ENST00000257910.3
TSPAN31
tetraspanin 31
chr16_-_20338748 4.06 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr11_+_128563652 4.05 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_-_160473114 3.95 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_-_111092930 3.88 ENST00000257435.7
NREP
neuronal regeneration related protein
chr5_+_140227048 3.87 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr1_-_161279749 3.84 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ
myelin protein zero
chr6_-_32821599 3.73 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_-_155461515 3.68 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr15_+_42131011 3.67 ENST00000458483.1
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr1_+_50571949 3.65 ENST00000357083.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr3_-_164875850 3.58 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr6_+_134210243 3.55 ENST00000367882.4
TCF21
transcription factor 21
chr1_-_161519682 3.54 ENST00000367969.3
ENST00000443193.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr3_+_111260954 3.51 ENST00000283285.5
CD96
CD96 molecule
chr3_-_183735731 3.48 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr17_+_41132564 3.46 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr3_+_111260856 3.40 ENST00000352690.4
CD96
CD96 molecule
chr10_+_17794251 3.38 ENST00000377495.1
ENST00000338221.5
TMEM236
transmembrane protein 236
chr7_-_82792215 3.37 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr12_+_56324933 3.32 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr2_-_175547571 3.32 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WIPF1
WAS/WASL interacting protein family, member 1
chr19_+_57106647 3.15 ENST00000328070.6
ZNF71
zinc finger protein 71
chr3_-_50649192 3.14 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr5_+_40909354 3.10 ENST00000313164.9
C7
complement component 7
chr5_-_111093167 3.02 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr12_+_20848486 2.99 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr10_-_104179682 2.97 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr12_+_27396901 2.94 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr22_-_31536480 2.94 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr2_-_177502254 2.94 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr17_-_58603568 2.77 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr11_+_65657875 2.72 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr13_-_26795840 2.70 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr19_+_44617511 2.62 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr2_-_160472952 2.62 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr14_+_65381079 2.52 ENST00000549115.1
ENST00000607599.1
ENST00000548752.2
ENST00000359118.2
ENST00000552002.2
ENST00000551947.1
ENST00000551093.1
ENST00000542227.1
ENST00000447296.2
ENST00000549987.1
CHURC1
FNTB
CHURC1-FNTB
churchill domain containing 1
farnesyltransferase, CAAX box, beta
CHURC1-FNTB readthrough
chr2_-_37193606 2.52 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr7_-_115670792 2.46 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr9_-_116163400 2.38 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr12_+_20848282 2.20 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr7_-_115670804 2.16 ENST00000320239.7
TFEC
transcription factor EC
chr10_-_116444371 2.12 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr19_-_50529193 2.04 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr12_+_20848377 1.99 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr1_+_155146318 1.98 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr6_+_167525277 1.92 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr10_+_102790980 1.92 ENST00000393459.1
ENST00000224807.5
SFXN3
sideroflexin 3
chr5_-_111093340 1.88 ENST00000508870.1
NREP
neuronal regeneration related protein
chr22_+_24551765 1.83 ENST00000337989.7
CABIN1
calcineurin binding protein 1
chr1_-_120935894 1.83 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr1_-_144994840 1.80 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_202431859 1.76 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr5_-_111093081 1.71 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr5_-_111092873 1.70 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr6_+_32821924 1.69 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_+_155838337 1.67 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr5_-_64777733 1.65 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr20_+_8112824 1.53 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr16_+_4674787 1.50 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr11_-_118436707 1.47 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr1_+_149754227 1.45 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr3_+_159570722 1.42 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr12_+_53443963 1.36 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_+_44669221 1.33 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226
zinc finger protein 226
chr5_+_137203465 1.31 ENST00000239926.4
MYOT
myotilin
chr3_-_52864680 1.29 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr9_-_95166841 1.28 ENST00000262551.4
OGN
osteoglycin
chr11_-_10590238 1.18 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_+_171561127 1.17 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr5_-_127674883 1.11 ENST00000507835.1
FBN2
fibrillin 2
chr1_-_144994909 1.11 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_+_35773242 1.10 ENST00000222304.3
HAMP
hepcidin antimicrobial peptide
chr2_+_113885138 1.10 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr6_+_25754927 1.07 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr19_-_7812397 1.05 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chr6_-_32152064 1.02 ENST00000375076.4
ENST00000375070.3
AGER
advanced glycosylation end product-specific receptor
chrX_+_135570046 0.95 ENST00000370648.3
BRS3
bombesin-like receptor 3
chr19_+_50528971 0.95 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473
zinc finger protein 473
chr9_-_95166884 0.93 ENST00000375561.5
OGN
osteoglycin
chr7_+_117120017 0.92 ENST00000003084.6
ENST00000454343.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr4_-_76957214 0.90 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chrX_-_63005405 0.89 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_+_60083118 0.85 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_-_49245936 0.83 ENST00000308025.3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr3_+_5020801 0.83 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr16_+_4674814 0.70 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chrX_+_144908928 0.68 ENST00000408967.2
TMEM257
transmembrane protein 257
chr7_+_117120106 0.63 ENST00000426809.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr11_-_119999611 0.62 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr11_-_85338311 0.61 ENST00000376104.2
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_25874440 0.59 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr6_+_35995552 0.59 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr1_+_161632937 0.56 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr16_+_19467772 0.56 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr20_-_21494654 0.52 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr20_+_42136308 0.52 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr3_+_187871060 0.50 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_171627269 0.50 ENST00000442456.1
AC007405.4
AC007405.4
chr19_-_7812446 0.50 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr4_-_187476721 0.47 ENST00000307161.5
MTNR1A
melatonin receptor 1A
chr3_-_137851220 0.44 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr5_+_137203557 0.39 ENST00000515645.1
MYOT
myotilin
chr2_+_210444748 0.38 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr13_+_97928395 0.37 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr1_+_9299895 0.36 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr14_-_20881579 0.33 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1
telomerase-associated protein 1
chr19_-_39881669 0.31 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chrX_+_138612889 0.31 ENST00000218099.2
ENST00000394090.2
F9
coagulation factor IX
chr11_+_123986069 0.29 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr3_-_194119995 0.28 ENST00000323007.3
GP5
glycoprotein V (platelet)
chr11_-_119999539 0.25 ENST00000541857.1
TRIM29
tripartite motif containing 29
chrX_+_54834159 0.23 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr6_+_108977520 0.18 ENST00000540898.1
FOXO3
forkhead box O3
chr15_-_60690932 0.16 ENST00000559818.1
ANXA2
annexin A2
chr19_+_50529212 0.13 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473
zinc finger protein 473
chrX_-_154563889 0.12 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr5_+_137203541 0.06 ENST00000421631.2
MYOT
myotilin
chr11_-_62752455 0.06 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr2_-_79386786 0.05 ENST00000393878.1
ENST00000305165.2
ENST00000409839.3
REG3A
regenerating islet-derived 3 alpha
chr5_-_121413974 0.02 ENST00000231004.4
LOX
lysyl oxidase

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0007412 axon target recognition(GO:0007412)
3.0 12.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.9 11.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
2.6 15.4 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.3 6.9 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
2.3 36.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
2.2 8.8 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
2.1 10.3 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.8 10.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
1.8 35.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
1.2 7.5 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
1.2 3.6 GO:0072276 branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.1 9.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
1.1 4.5 GO:2000570 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
1.1 5.5 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
1.0 15.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
1.0 4.9 GO:1990834 response to odorant(GO:1990834)
0.9 45.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.9 3.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.9 2.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.8 6.7 GO:0006013 mannose metabolic process(GO:0006013)
0.8 2.4 GO:0070541 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.6 1.9 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.6 4.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 7.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 5.9 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.5 1.6 GO:0046968 peptide antigen transport(GO:0046968)
0.5 1.5 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.5 1.5 GO:0090427 activation of meiosis(GO:0090427)
0.4 2.5 GO:0018343 protein farnesylation(GO:0018343)
0.4 10.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 5.5 GO:0060271 cilium morphogenesis(GO:0060271)
0.4 6.6 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.4 1.1 GO:1903413 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.3 1.0 GO:1905204 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.3 7.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 0.8 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.2 3.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 4.1 GO:0035855 megakaryocyte development(GO:0035855)
0.2 2.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 2.0 GO:0099612 protein localization to axon(GO:0099612)
0.2 6.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.5 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 0.3 GO:0043318 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.1 3.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 6.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 9.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 21.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 2.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.7 GO:0060539 diaphragm development(GO:0060539)
0.1 2.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 5.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 2.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.9 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 2.2 GO:0098743 cell aggregation(GO:0098743)
0.1 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 3.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 2.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 3.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 8.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 8.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 26.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 4.0 GO:0035418 protein localization to synapse(GO:0035418)
0.1 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 4.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 6.9 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 1.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 2.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 1.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.7 GO:0060976 coronary vasculature development(GO:0060976)
0.0 10.8 GO:0032259 methylation(GO:0032259)
0.0 0.5 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 1.8 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.6 GO:0006811 ion transport(GO:0006811)
0.0 1.2 GO:0055072 iron ion homeostasis(GO:0055072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 45.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.8 8.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.2 15.4 GO:0097418 neurofibrillary tangle(GO:0097418)
1.0 5.2 GO:0045298 tubulin complex(GO:0045298)
0.9 10.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 2.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.6 3.7 GO:0042825 TAP complex(GO:0042825)
0.6 11.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.0 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.7 GO:1990635 proximal dendrite(GO:1990635)
0.2 7.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 5.5 GO:0034451 centriolar satellite(GO:0034451)
0.2 9.2 GO:1904115 axon cytoplasm(GO:1904115)
0.2 7.6 GO:0016592 mediator complex(GO:0016592)
0.2 41.4 GO:0030426 growth cone(GO:0030426)
0.2 9.3 GO:0045171 intercellular bridge(GO:0045171)
0.2 8.7 GO:0001772 immunological synapse(GO:0001772)
0.1 1.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 2.9 GO:0042629 mast cell granule(GO:0042629)
0.1 3.4 GO:0099738 cell cortex region(GO:0099738)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 3.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 5.9 GO:0055037 recycling endosome(GO:0055037)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.8 GO:0031672 A band(GO:0031672)
0.0 5.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 9.0 GO:0098793 presynapse(GO:0098793)
0.0 42.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.7 GO:0016605 PML body(GO:0016605)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
3.7 45.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.9 8.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.3 7.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.3 9.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.7 12.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.6 9.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.9 7.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.8 11.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.8 10.3 GO:0042608 T cell receptor binding(GO:0042608)
0.8 15.4 GO:0051787 misfolded protein binding(GO:0051787)
0.7 6.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.6 2.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.6 3.7 GO:0046979 TAP2 binding(GO:0046979)
0.6 9.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 1.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 10.9 GO:0070403 NAD+ binding(GO:0070403)
0.4 7.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 6.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 7.2 GO:0019864 IgG binding(GO:0019864)
0.4 3.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.4 6.7 GO:0005522 profilin binding(GO:0005522)
0.4 1.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.0 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.2 0.9 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 8.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 4.3 GO:0004697 protein kinase C activity(GO:0004697)
0.2 0.5 GO:0032093 SAM domain binding(GO:0032093)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 1.6 GO:0046790 virion binding(GO:0046790)
0.1 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 1.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.4 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.1 3.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 5.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 16.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 4.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 5.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0070402 NADPH binding(GO:0070402)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.1 5.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 11.0 GO:0008168 methyltransferase activity(GO:0008168)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 14.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 2.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 4.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 3.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 2.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 2.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0015075 ion transmembrane transporter activity(GO:0015075)
0.0 3.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 12.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.8 GO:0008047 enzyme activator activity(GO:0008047)
0.0 19.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 45.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 3.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.4 22.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 5.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 46.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 6.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 5.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 9.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 11.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 4.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 4.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 3.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 45.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.7 8.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.4 10.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 7.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 12.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 15.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 4.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 6.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 6.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 8.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 22.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 10.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 4.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 7.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 7.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 3.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 8.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway