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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for STAT5A

Z-value: 0.40

Motif logo

Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_404405610.454.6e-12Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_15103621 21.42 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr3_-_50649192 20.59 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chr3_+_50649302 19.98 ENST00000446044.1
mitogen-activated protein kinase-activated protein kinase 3
chr6_+_32605195 19.32 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr2_-_89292422 18.05 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr6_+_32407619 16.62 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr1_-_36937075 16.34 ENST00000464465.2
colony stimulating factor 3 receptor (granulocyte)
chr19_+_42724423 16.25 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr2_-_89399845 14.00 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr6_+_33048222 13.89 ENST00000428835.1
major histocompatibility complex, class II, DP beta 1
chr2_+_90198535 13.30 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr12_-_15114603 12.98 ENST00000228945.4
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_158801095 12.90 ENST00000368141.4
myeloid cell nuclear differentiation antigen
chr4_-_71532339 12.06 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_-_15114492 11.98 ENST00000541546.1
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_36948879 11.90 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
colony stimulating factor 3 receptor (granulocyte)
chr17_-_76356148 11.88 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chr1_+_111415757 11.73 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr2_+_90139056 11.63 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr1_+_233086326 11.17 ENST00000366628.5
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr22_+_23241661 11.14 ENST00000390322.2
immunoglobulin lambda joining 2
chr6_+_31582961 11.03 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr19_-_10446449 10.10 ENST00000592439.1
intercellular adhesion molecule 3
chr5_-_140013275 9.91 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr1_-_159046617 9.73 ENST00000368130.4
absent in melanoma 2
chr5_-_138725560 9.66 ENST00000412103.2
ENST00000457570.2
marginal zone B and B1 cell-specific protein
chr5_-_138725594 9.61 ENST00000302125.8
marginal zone B and B1 cell-specific protein
chrY_+_15016725 9.60 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr22_+_37257015 9.53 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
neutrophil cytosolic factor 4, 40kDa
chr7_+_74188309 9.50 ENST00000289473.4
ENST00000433458.1
neutrophil cytosolic factor 1
chr2_-_89340242 9.42 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr19_+_18284477 9.32 ENST00000407280.3
interferon, gamma-inducible protein 30
chr17_+_40440481 9.13 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr9_-_97402531 9.08 ENST00000415431.1
fructose-1,6-bisphosphatase 1
chr19_-_44809121 8.93 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
zinc finger protein 235
chr7_-_36634181 8.86 ENST00000538464.1
acyloxyacyl hydrolase (neutrophil)
chr2_+_17935383 8.74 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr17_-_34207295 8.72 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr7_-_29186008 8.72 ENST00000396276.3
ENST00000265394.5
carboxypeptidase, vitellogenic-like
chr3_+_111260954 8.68 ENST00000283285.5
CD96 molecule
chr17_-_62084241 8.63 ENST00000449662.2
intercellular adhesion molecule 2
chr10_-_75571341 8.62 ENST00000309979.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_+_85804614 8.61 ENST00000263864.5
ENST00000409760.1
vesicle-associated membrane protein 8
chr1_+_158975744 8.56 ENST00000426592.2
interferon, gamma-inducible protein 16
chr10_-_75571566 8.52 ENST00000299641.4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_-_175547571 8.46 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WAS/WASL interacting protein family, member 1
chr7_+_80275621 8.43 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr22_+_23247030 8.36 ENST00000390324.2
immunoglobulin lambda joining 3
chr10_-_6622201 8.36 ENST00000539722.1
ENST00000397176.2
protein kinase C, theta
chr22_-_37640456 8.27 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_37407212 8.26 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
zinc finger protein 568
chr9_-_110251836 8.25 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr5_-_169694286 8.25 ENST00000521416.1
ENST00000520344.1
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_-_37640277 8.23 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_-_6836156 8.22 ENST00000382679.2
defensin, alpha 1
chr6_+_32605134 7.99 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr14_+_21249200 7.71 ENST00000304677.2
ribonuclease, RNase A family, k6
chr9_-_97402413 7.71 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr19_-_51875894 7.66 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr7_-_37026108 7.55 ENST00000396045.3
engulfment and cell motility 1
chr17_-_29641084 7.50 ENST00000544462.1
ecotropic viral integration site 2B
chr2_+_17935119 7.50 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr16_-_75498308 7.41 ENST00000569540.1
transmembrane protein 170A
chrY_+_15016013 7.40 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr7_+_142829162 7.34 ENST00000291009.3
prolactin-induced protein
chr22_-_38902300 7.33 ENST00000403230.1
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr19_+_1041212 7.29 ENST00000433129.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr2_+_163200848 7.28 ENST00000233612.4
grancalcin, EF-hand calcium binding protein
chr12_+_32112340 7.14 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr11_-_10590238 7.08 ENST00000256178.3
lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_32820529 7.08 ENST00000425148.2
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_29641104 7.06 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr14_-_25103388 7.05 ENST00000526004.1
ENST00000415355.3
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr5_+_40909354 7.05 ENST00000313164.9
complement component 7
chr2_+_90192768 7.00 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr7_+_80275752 7.00 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr14_-_25103472 6.98 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_+_54704610 6.80 ENST00000302907.4
ribosomal protein S9
chr5_-_169725231 6.79 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr13_-_46964177 6.73 ENST00000389908.3
KIAA0226-like
chr11_-_615570 6.61 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr15_-_38856836 6.61 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr1_-_161519579 6.60 ENST00000426740.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr16_-_21663919 6.56 ENST00000569602.1
immunoglobulin superfamily, member 6
chr1_+_158979792 6.47 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr6_-_32634425 6.42 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
major histocompatibility complex, class II, DQ beta 1
chr12_-_54689532 6.37 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr7_+_117120017 6.34 ENST00000003084.6
ENST00000454343.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_-_117537240 6.28 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr5_-_172198190 6.22 ENST00000239223.3
dual specificity phosphatase 1
chr11_+_117049910 6.20 ENST00000431081.2
ENST00000524842.1
SID1 transmembrane family, member 2
chr1_-_161600822 6.17 ENST00000534776.1
ENST00000540048.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_+_128563652 6.16 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr19_+_55128576 6.12 ENST00000396331.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr14_+_75988851 6.03 ENST00000555504.1
basic leucine zipper transcription factor, ATF-like
chr14_+_61789382 5.98 ENST00000555082.1
protein kinase C, eta
chr7_-_36764004 5.88 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr3_+_38179969 5.87 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr16_-_20338748 5.77 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr7_+_139529040 5.74 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr1_+_158979680 5.72 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr22_-_24096562 5.71 ENST00000398465.3
pre-B lymphocyte 3
chr6_+_144471643 5.70 ENST00000367568.4
syntaxin 11
chr19_-_40023450 5.67 ENST00000326282.4
EP300 interacting inhibitor of differentiation 2B
chr17_+_77681075 5.63 ENST00000397549.2
CTD-2116F7.1
chr22_-_38902325 5.62 ENST00000396821.3
ENST00000381633.3
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr13_+_111767650 5.62 ENST00000449979.1
ENST00000370623.3
Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_53468332 5.60 ENST00000262133.6
retinoblastoma-like 2 (p130)
chr20_-_43280361 5.58 ENST00000372874.4
adenosine deaminase
chr1_-_161600990 5.58 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_40324767 5.47 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_+_55361898 5.45 ENST00000326321.3
ENST00000270442.5
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
chr1_+_158979686 5.44 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr12_+_56324756 5.42 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr21_+_34602377 5.39 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
interferon (alpha, beta and omega) receptor 2
chr1_-_161600942 5.38 ENST00000421702.2
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_59084647 5.32 ENST00000594234.1
ENST00000596039.1
myeloid zinc finger 1
chr11_-_10590118 5.30 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_161519682 5.27 ENST00000367969.3
ENST00000443193.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr5_+_137225158 5.26 ENST00000290431.5
polycystic kidney disease 2-like 2
chr10_-_6019552 5.21 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr17_-_80408569 5.20 ENST00000577696.1
ENST00000577471.1
ENST00000582545.2
ENST00000437807.2
ENST00000583617.1
ENST00000578913.1
ENST00000336995.7
ENST00000577834.1
ENST00000342572.8
ENST00000585064.1
ENST00000585080.1
ENST00000578919.1
ENST00000306645.5
ENST00000434650.2
chromosome 17 open reading frame 62
chr7_+_139528952 5.18 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr19_+_51728316 5.10 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33 molecule
chr13_-_33112956 5.06 ENST00000505213.1
NEDD4 binding protein 2-like 2
chr21_+_34602200 5.04 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
interferon (alpha, beta and omega) receptor 2
chr15_+_58430567 5.03 ENST00000536493.1
aquaporin 9
chr8_+_104427581 5.01 ENST00000521716.1
ENST00000521971.1
ENST00000519682.1
DDB1 and CUL4 associated factor 13
chr19_+_52264104 4.98 ENST00000340023.6
formyl peptide receptor 2
chr6_-_39693111 4.97 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
kinesin family member 6
chr6_-_137539651 4.97 ENST00000543628.1
interferon gamma receptor 1
chr17_-_40021656 4.88 ENST00000319121.3
kelch-like family member 11
chr17_-_76124711 4.83 ENST00000306591.7
ENST00000590602.1
transmembrane channel-like 6
chr15_-_64648273 4.83 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr17_-_27224621 4.82 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
flotillin 2
chr15_-_73076030 4.82 ENST00000311669.8
ADP-dependent glucokinase
chr3_+_111260856 4.81 ENST00000352690.4
CD96 molecule
chr5_-_180236811 4.80 ENST00000446023.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_-_56727487 4.77 ENST00000548043.1
ENST00000425394.2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_65253506 4.76 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr5_+_150400124 4.76 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
glutathione peroxidase 3 (plasma)
chr6_+_131894284 4.72 ENST00000368087.3
ENST00000356962.2
arginase 1
chr1_-_25558984 4.72 ENST00000236273.4
SYF2 pre-mRNA-splicing factor
chr19_-_50529193 4.72 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chrY_+_22737604 4.72 ENST00000361365.2
eukaryotic translation initiation factor 1A, Y-linked
chr19_+_44617511 4.71 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
zinc finger protein 225
chr10_+_30722866 4.67 ENST00000263056.1
mitogen-activated protein kinase kinase kinase 8
chr9_-_88356733 4.64 ENST00000376083.3
ATP/GTP binding protein 1
chr19_+_10197463 4.59 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr4_+_128651530 4.58 ENST00000281154.4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr16_-_21663950 4.58 ENST00000268389.4
immunoglobulin superfamily, member 6
chr14_+_95078714 4.57 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr6_-_41703952 4.57 ENST00000358871.2
ENST00000403298.4
transcription factor EB
chr19_+_55327923 4.57 ENST00000391728.4
ENST00000326542.7
ENST00000358178.4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr7_-_76829125 4.56 ENST00000248598.5
fibrinogen-like 2
chrX_+_122993657 4.45 ENST00000434753.3
ENST00000430625.1
X-linked inhibitor of apoptosis
chr12_-_56727676 4.43 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr10_-_72362515 4.42 ENST00000373209.2
ENST00000441259.1
perforin 1 (pore forming protein)
chr11_-_22851367 4.35 ENST00000354193.4
small VCP/p97-interacting protein
chr1_+_158325684 4.34 ENST00000368162.2
CD1e molecule
chr11_-_59383617 4.33 ENST00000263847.1
oxysterol binding protein
chr13_-_99959641 4.32 ENST00000376414.4
G protein-coupled receptor 183
chr5_-_64777733 4.31 ENST00000381055.3
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_+_26727125 4.27 ENST00000376236.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_121461097 4.25 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr13_-_33112899 4.23 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
NEDD4 binding protein 2-like 2
chr16_+_27413483 4.22 ENST00000337929.3
ENST00000564089.1
interleukin 21 receptor
chr22_-_24096630 4.20 ENST00000248948.3
pre-B lymphocyte 3
chr6_+_35995552 4.17 ENST00000468133.1
mitogen-activated protein kinase 14
chr22_+_22936998 4.16 ENST00000390303.2
immunoglobulin lambda variable 3-32 (non-functional)
chr4_+_87856129 4.15 ENST00000395146.4
ENST00000507468.1
AF4/FMR2 family, member 1
chr16_-_1661988 4.14 ENST00000426508.2
intraflagellar transport 140 homolog (Chlamydomonas)
chr3_+_101443476 4.14 ENST00000327230.4
ENST00000494050.1
centrosomal protein 97kDa
chr4_-_38806404 4.12 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
toll-like receptor 1
chr20_+_16729003 4.12 ENST00000246081.2
otoraplin
chr9_-_88356789 4.10 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
ATP/GTP binding protein 1
chr19_+_54705025 4.10 ENST00000441429.1
ribosomal protein S9
chr15_-_86338134 4.10 ENST00000337975.5
kelch-like family member 25
chr17_+_75123947 4.08 ENST00000586429.1
SEC14-like 1 (S. cerevisiae)
chr12_+_56324933 4.08 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr1_+_36690011 4.07 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
thyroid hormone receptor associated protein 3
chr8_+_95565947 4.07 ENST00000523011.1
RP11-267M23.4
chr13_-_45915221 4.07 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
tumor protein, translationally-controlled 1
chr4_+_15779901 4.06 ENST00000226279.3
CD38 molecule
chr5_+_137225125 4.05 ENST00000350250.4
ENST00000508638.1
ENST00000502810.1
ENST00000508883.1
polycystic kidney disease 2-like 2
chr16_+_67198683 4.04 ENST00000517685.1
ENST00000521374.1
ENST00000584272.1
heat shock transcription factor 4
chr1_+_12123414 4.04 ENST00000263932.2
tumor necrosis factor receptor superfamily, member 8
chr12_+_93964746 4.04 ENST00000536696.2
suppressor of cytokine signaling 2
chr19_+_55281260 4.03 ENST00000336077.6
ENST00000291633.7
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr8_-_56685966 3.99 ENST00000334667.2
transmembrane protein 68
chr1_+_149754227 3.98 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr7_+_117120106 3.96 ENST00000426809.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr6_+_20534672 3.94 ENST00000274695.4
ENST00000378624.4
CDK5 regulatory subunit associated protein 1-like 1
chr9_-_89562104 3.94 ENST00000298743.7
growth arrest-specific 1
chr8_+_27168988 3.94 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chrY_+_22737678 3.94 ENST00000382772.3
eukaryotic translation initiation factor 1A, Y-linked
chr4_-_40517984 3.94 ENST00000381795.6
RNA binding motif protein 47
chrX_+_15767971 3.93 ENST00000479740.1
ENST00000454127.2
carbonic anhydrase VB, mitochondrial
chr15_-_75660919 3.91 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
mannosidase, alpha, class 2C, member 1
chr4_-_185395672 3.90 ENST00000393593.3
interferon regulatory factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.6 46.4 GO:0071461 cellular response to redox state(GO:0071461)
5.5 16.4 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
5.4 16.2 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
4.5 17.9 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
4.2 16.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
4.2 16.6 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
3.9 19.3 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
3.9 19.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.6 18.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
3.4 10.3 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
3.1 9.3 GO:0046102 hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
2.9 8.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
2.9 17.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.7 8.2 GO:0035915 pore formation in membrane of other organism(GO:0035915)
2.6 15.4 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
2.5 20.0 GO:0044351 macropinocytosis(GO:0044351)
2.4 7.3 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.3 9.1 GO:0000255 allantoin metabolic process(GO:0000255)
2.3 11.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.1 12.8 GO:0070269 pyroptosis(GO:0070269)
2.1 8.4 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
2.1 6.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
2.0 6.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
2.0 6.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
2.0 14.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.0 2.0 GO:0006544 glycine metabolic process(GO:0006544)
1.8 7.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.8 7.1 GO:0046967 cytosol to ER transport(GO:0046967)
1.8 10.6 GO:0016554 cytidine to uridine editing(GO:0016554)
1.6 4.8 GO:0006982 response to lipid hydroperoxide(GO:0006982)
1.5 6.1 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
1.5 4.4 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.5 4.4 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
1.5 4.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.4 10.1 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
1.4 4.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.4 10.0 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.4 4.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.4 15.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
1.3 4.0 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.3 3.9 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
1.3 3.9 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.3 28.2 GO:0097186 amelogenesis(GO:0097186)
1.3 3.8 GO:1903413 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
1.2 6.1 GO:0015722 canalicular bile acid transport(GO:0015722)
1.2 3.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.2 4.8 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.2 5.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
1.1 3.4 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.1 6.6 GO:0032252 secretory granule localization(GO:0032252)
1.1 3.3 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
1.1 3.3 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.1 2.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.1 12.7 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.1 3.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.0 3.1 GO:0045062 extrathymic T cell selection(GO:0045062)
1.0 6.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.0 4.0 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.0 3.0 GO:0097254 renal tubular secretion(GO:0097254)
1.0 8.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.0 2.0 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.9 4.7 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.9 2.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.9 1.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.9 3.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.9 6.2 GO:0033227 dsRNA transport(GO:0033227)
0.9 2.6 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.9 2.6 GO:1990637 response to prolactin(GO:1990637)
0.9 3.5 GO:0003335 corneocyte development(GO:0003335)
0.8 6.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.8 5.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.8 5.6 GO:0008218 bioluminescence(GO:0008218)
0.8 19.0 GO:0045730 respiratory burst(GO:0045730)
0.8 3.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.8 2.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.8 7.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.8 2.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.8 3.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.7 6.0 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7 2.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.7 2.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.7 6.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.7 2.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.7 1.4 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.7 29.9 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.7 3.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.7 13.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.7 2.1 GO:0048485 sympathetic nervous system development(GO:0048485)
0.7 11.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.7 2.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.7 2.1 GO:0006710 androgen catabolic process(GO:0006710)
0.7 2.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.7 17.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.7 2.0 GO:0046968 peptide antigen transport(GO:0046968)
0.7 25.6 GO:1900077 negative regulation of cellular response to insulin stimulus(GO:1900077)
0.7 2.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.6 2.6 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.6 84.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.6 1.3 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.6 11.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 4.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.6 3.7 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.6 10.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 3.0 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.6 5.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 2.3 GO:0042713 sperm ejaculation(GO:0042713)
0.6 12.9 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.6 8.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.6 1.7 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.6 4.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.6 2.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 5.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 3.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.5 1.1 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.5 2.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.5 5.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.5 1.6 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.5 2.1 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.5 1.6 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.5 1.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 3.6 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.5 1.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.5 3.6 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.5 2.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 2.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.5 2.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.5 5.4 GO:0002418 immune response to tumor cell(GO:0002418)
0.5 1.5 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.5 85.9 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.5 3.9 GO:0006013 mannose metabolic process(GO:0006013)
0.5 1.5 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.5 1.5 GO:0006014 D-ribose metabolic process(GO:0006014)
0.5 1.9 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5 1.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.9 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 11.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.5 1.9 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.5 2.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.5 4.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.4 9.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.4 3.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.4 1.8 GO:0070475 rRNA base methylation(GO:0070475)
0.4 6.0 GO:0042832 defense response to protozoan(GO:0042832)
0.4 1.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.4 2.6 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.4 1.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.4 6.0 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 3.8 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 6.2 GO:1903504 peptidyl-threonine dephosphorylation(GO:0035970) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.4 4.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.4 4.9 GO:0002475 antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4 2.4 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.4 1.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4 11.1 GO:0007520 myoblast fusion(GO:0007520)
0.4 3.2 GO:0006600 creatine metabolic process(GO:0006600)
0.4 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.9 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 6.2 GO:0035855 megakaryocyte development(GO:0035855)
0.4 4.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.4 1.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.4 3.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 3.0 GO:0007288 acrosome assembly(GO:0001675) sperm axoneme assembly(GO:0007288)
0.4 8.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.4 17.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.4 2.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 1.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 1.4 GO:1902202 regulation of endothelial tube morphogenesis(GO:1901509) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 2.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 1.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 6.1 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.3 2.0 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) response to oleic acid(GO:0034201)
0.3 1.3 GO:0071321 cellular response to cGMP(GO:0071321)
0.3 2.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.3 1.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 4.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 1.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 19.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.3 2.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 8.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.3 5.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3 1.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.3 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.3 2.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.3 1.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 8.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 1.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.3 0.5 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 5.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.8 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.3 1.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.3 1.5 GO:0060235 embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.3 1.5 GO:0019530 taurine metabolic process(GO:0019530)
0.3 9.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 3.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 2.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 3.5 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 6.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 4.1 GO:0001502 cartilage condensation(GO:0001502)
0.2 2.6 GO:0006702 androgen biosynthetic process(GO:0006702)
0.2 1.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 1.8 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 2.5 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 3.2 GO:0051546 keratinocyte migration(GO:0051546)
0.2 4.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2 0.7 GO:0048852 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.2 2.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 2.7 GO:0070307 lens fiber cell development(GO:0070307)
0.2 7.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.2 1.8 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 2.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 7.7 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.2 13.3 GO:0045576 mast cell activation(GO:0045576)
0.2 2.6 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768)
0.2 1.1 GO:0015747 urate transport(GO:0015747)
0.2 3.4 GO:0048266 behavioral response to pain(GO:0048266)
0.2 1.7 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.2 0.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.2 3.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.2 4.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.7 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 0.8 GO:1903012 positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.2 4.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 1.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.2 2.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.2 1.8 GO:0006265 DNA topological change(GO:0006265)
0.2 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.2 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 8.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.0 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.2 3.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 2.1 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2 0.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 1.7 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.2 3.0 GO:0019835 cytolysis(GO:0019835)
0.2 2.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.2 4.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 3.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.9 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 2.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 4.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 1.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 8.4 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.3 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 5.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 7.3 GO:0006968 cellular defense response(GO:0006968)
0.1 4.7 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 1.5 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.5 GO:0007512 adult heart development(GO:0007512)
0.1 1.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 14.4 GO:0002377 immunoglobulin production(GO:0002377)
0.1 4.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 5.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 4.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 1.0 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.9 GO:0010447 response to acidic pH(GO:0010447)
0.1 5.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 1.3 GO:0032620 interleukin-17 production(GO:0032620)
0.1 0.9 GO:1903799 antral ovarian follicle growth(GO:0001547) vagina development(GO:0060068) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.8 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.4 GO:0072143 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 3.6 GO:0030101 natural killer cell activation(GO:0030101)
0.1 1.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 1.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.1 1.2 GO:0050832 defense response to fungus(GO:0050832)
0.1 4.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.8 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.1 1.1 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 3.6 GO:0046849 bone remodeling(GO:0046849)
0.1 1.0 GO:0070831 basement membrane assembly(GO:0070831)
0.1 3.9 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 3.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 2.2 GO:0046688 response to copper ion(GO:0046688)
0.1 3.3 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 0.6 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.9 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.5 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452)
0.1 1.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 1.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 4.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.1 1.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 3.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 2.6 GO:0034332 adherens junction organization(GO:0034332)
0.1 2.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.3 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 1.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.4 GO:0002027 regulation of heart rate(GO:0002027)
0.1 0.9 GO:0009299 mRNA transcription(GO:0009299)
0.1 1.1 GO:0060349 bone morphogenesis(GO:0060349)
0.1 0.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 1.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.9 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.8 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 0.8 GO:0017145 stem cell division(GO:0017145)
0.1 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.7 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 1.4 GO:0031214 biomineral tissue development(GO:0031214)
0.0 2.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 2.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.5 GO:0009404 toxin metabolic process(GO:0009404)
0.0 4.0 GO:0006954 inflammatory response(GO:0006954)
0.0 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 2.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 4.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.0 GO:0060147 regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 4.6 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.5 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.9 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.7 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 2.3 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 1.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 1.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.9 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 2.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.5 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 70.1 GO:0042613 MHC class II protein complex(GO:0042613)
3.1 9.2 GO:0031251 PAN complex(GO:0031251)
3.1 15.3 GO:0036398 TCR signalosome(GO:0036398)
2.7 8.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.4 19.0 GO:0032010 phagolysosome(GO:0032010)
2.1 16.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
2.1 10.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
1.9 9.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.4 12.8 GO:0005579 membrane attack complex(GO:0005579)
1.2 5.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.2 7.1 GO:0042825 TAP complex(GO:0042825)
1.1 9.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.0 3.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.0 19.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.9 12.2 GO:0005577 fibrinogen complex(GO:0005577)
0.9 3.7 GO:0097224 sperm connecting piece(GO:0097224)
0.8 4.1 GO:0045298 tubulin complex(GO:0045298)
0.8 3.0 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.7 14.5 GO:0001891 phagocytic cup(GO:0001891)
0.7 5.6 GO:0000322 storage vacuole(GO:0000322)
0.7 4.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.7 13.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 4.4 GO:0044194 cytolytic granule(GO:0044194)
0.6 7.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 10.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 1.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.6 12.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.6 2.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 28.9 GO:0001772 immunological synapse(GO:0001772)
0.5 5.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.5 3.8 GO:0045179 apical cortex(GO:0045179)
0.5 2.8 GO:1990769 proximal neuron projection(GO:1990769)
0.5 6.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 1.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 1.7 GO:0005606 laminin-1 complex(GO:0005606)
0.4 2.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.4 3.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 1.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.4 11.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 1.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.3 1.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.3 2.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 12.5 GO:0016592 mediator complex(GO:0016592)
0.3 4.3 GO:0042101 T cell receptor complex(GO:0042101)
0.3 4.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 9.6 GO:0042629 mast cell granule(GO:0042629)
0.3 2.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 3.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.3 3.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 5.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 19.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.9 GO:0097165 nuclear stress granule(GO:0097165)
0.3 3.2 GO:0001741 XY body(GO:0001741)
0.3 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 2.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 3.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.2 3.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 12.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 27.0 GO:0031225 anchored component of membrane(GO:0031225)
0.2 6.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.8 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 18.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 8.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 14.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 5.7 GO:0031201 SNARE complex(GO:0031201)
0.2 1.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 9.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 17.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 2.7 GO:0042588 zymogen granule(GO:0042588)
0.2 8.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 4.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 5.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.0 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 5.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 3.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 1.9 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 6.1 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0000800 lateral element(GO:0000800)
0.1 5.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 12.9 GO:0016605 PML body(GO:0016605)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 4.1 GO:0031904 endosome lumen(GO:0031904)
0.1 2.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 5.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 17.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 6.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 9.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 2.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.5 GO:0035869 ciliary transition zone(GO:0035869)
0.1 3.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 5.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 5.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 33.5 GO:0016607 nuclear speck(GO:0016607)
0.1 2.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 7.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 103.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 0.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 1.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0005901 caveola(GO:0005901)
0.0 3.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.8 GO:0001726 ruffle(GO:0001726)
0.0 38.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 4.1 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 28.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
4.9 14.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
4.6 46.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
4.2 16.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
4.0 56.2 GO:0032395 MHC class II receptor activity(GO:0032395)
3.7 11.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
3.6 10.9 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
3.4 10.3 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
3.4 17.0 GO:0004905 type I interferon receptor activity(GO:0004905)
3.3 9.9 GO:0016019 peptidoglycan receptor activity(GO:0016019)
3.2 12.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
2.7 8.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
2.6 15.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
2.4 7.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.4 43.0 GO:0019864 IgG binding(GO:0019864)
2.3 13.8 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
2.2 17.4 GO:1990932 5.8S rRNA binding(GO:1990932)
2.1 6.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.0 16.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.9 19.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.7 8.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.4 4.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
1.3 6.6 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.3 3.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.3 5.0 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
1.2 3.7 GO:0005148 prolactin receptor binding(GO:0005148)
1.2 8.6 GO:0008142 oxysterol binding(GO:0008142)
1.2 4.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.2 6.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.2 7.1 GO:0046979 TAP2 binding(GO:0046979)
1.2 7.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.2 9.3 GO:0004000 adenosine deaminase activity(GO:0004000)
1.1 3.4 GO:1904599 advanced glycation end-product binding(GO:1904599)
1.1 6.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.1 5.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.1 4.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
1.1 3.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.1 20.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0 11.4 GO:0051525 NFAT protein binding(GO:0051525)
1.0 3.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.0 11.0 GO:0042834 peptidoglycan binding(GO:0042834)
1.0 5.0 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.9 5.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.9 2.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.7 3.0 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.7 15.9 GO:0042605 peptide antigen binding(GO:0042605)
0.7 2.7 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.7 4.1 GO:0039552 RIG-I binding(GO:0039552)
0.7 2.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.7 8.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.7 2.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.6 11.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 3.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.6 1.8 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.6 4.9 GO:0034235 GPI anchor binding(GO:0034235)
0.6 7.3 GO:0050700 CARD domain binding(GO:0050700)
0.6 1.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6 1.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.6 1.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.5 9.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 2.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 8.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 2.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 3.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 1.6 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 8.4 GO:0004697 protein kinase C activity(GO:0004697)
0.5 1.5 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.5 9.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.5 1.5 GO:0030145 manganese ion binding(GO:0030145)
0.5 2.5 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.5 4.9 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.5 1.5 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.5 1.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.5 1.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.5 2.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.5 1.8 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 1.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.5 2.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 1.8 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.5 4.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 7.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 3.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 1.8 GO:0001855 complement component C4b binding(GO:0001855)
0.4 2.6 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4 13.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 32.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.4 1.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.4 6.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 3.2 GO:0004111 creatine kinase activity(GO:0004111)
0.4 1.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 68.8 GO:0003823 antigen binding(GO:0003823)
0.4 4.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4 1.1 GO:0005549 odorant binding(GO:0005549)
0.4 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.4 3.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 3.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 4.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 2.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 4.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 3.3 GO:0031433 telethonin binding(GO:0031433)
0.3 2.3 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.3 39.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 1.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 2.0 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 3.7 GO:0032027 myosin light chain binding(GO:0032027)
0.3 4.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 3.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 1.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 1.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 2.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 3.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 5.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.3 3.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3 1.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 5.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 0.8 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.3 8.4 GO:0005123 death receptor binding(GO:0005123)
0.3 2.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 6.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 2.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 1.0 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 25.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 3.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 3.4 GO:0031402 sodium ion binding(GO:0031402)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 2.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 0.9 GO:0055102 lipase inhibitor activity(GO:0055102)
0.2 3.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.2 4.1 GO:0070330 aromatase activity(GO:0070330)
0.2 36.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 1.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 2.2 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.9 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 5.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 5.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 3.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 2.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.2 2.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 6.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.5 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 1.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 1.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 1.1 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.2 2.6 GO:0005537 mannose binding(GO:0005537)
0.2 16.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.2 0.8 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 6.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 3.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.0 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.9 GO:0036122 BMP binding(GO:0036122)
0.1 6.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 11.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 3.0 GO:0008201 heparin binding(GO:0008201)
0.1 1.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 3.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 4.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 2.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 4.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 4.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 5.5 GO:0050699 WW domain binding(GO:0050699)
0.1 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 6.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 1.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 18.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 3.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 4.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 2.7 GO:0031489 myosin V binding(GO:0031489)
0.1 6.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 4.4 GO:0043621 protein self-association(GO:0043621)
0.1 17.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.1 4.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 7.8 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 29.2 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.1 10.8 GO:0005178 integrin binding(GO:0005178)
0.1 5.9 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.5 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 2.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.9 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 2.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.3 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 30.5 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.7 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095) protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 26.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.8 25.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.7 21.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 17.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 9.1 PID IL27 PATHWAY IL27-mediated signaling events
0.7 73.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.6 31.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 3.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6 31.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 27.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.5 3.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.5 22.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.4 23.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 16.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.4 9.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 6.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 11.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 3.4 PID IL3 PATHWAY IL3-mediated signaling events
0.2 5.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 3.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 9.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 10.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 15.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 4.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 9.2 PID CDC42 PATHWAY CDC42 signaling events
0.2 2.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 4.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 9.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 6.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 6.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 4.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 2.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 3.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.4 ST ADRENERGIC Adrenergic Pathway
0.1 2.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 17.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 11.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.0 PID ATR PATHWAY ATR signaling pathway
0.1 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 15.2 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.7 PID ATM PATHWAY ATM pathway
0.0 5.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 44.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.6 15.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.5 7.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.3 34.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
1.1 19.3 REACTOME DEFENSINS Genes involved in Defensins
1.1 50.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.9 75.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8 8.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.7 17.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.7 2.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.7 30.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.7 1.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.6 9.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 31.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.5 9.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.5 15.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.5 18.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.5 5.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 6.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.4 6.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 7.8 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.4 9.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 12.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 32.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 13.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.3 2.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 4.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.3 1.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 12.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 43.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 3.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 9.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 5.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 17.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 6.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 2.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 4.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 12.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 9.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 5.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 3.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 4.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 5.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 7.6 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.2 2.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 2.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 3.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.9 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 6.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 5.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 6.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME SIGNALLING TO RAS Genes involved in Signalling to RAS
0.1 2.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 5.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 4.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 25.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 2.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 7.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides