GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
STAT5A Links Ensembl NCBI GeneCards UniProt	ENSG00000126561.12	signal transducer and activator of transcription 5A

Gene	Promoter	Pearson corr. coef.	P-value	Plot
STAT5A	hg19_v2_chr17_+_40440481_40440561	0.45	4.6e-12	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_15103621 Show fit	21.42	ENST00000536592.1	ARHGDIB Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr3_-_50649192 Show fit	20.59	ENST00000443053.2 ENST00000348721.3	CISH Links Ensembl NCBI GeneCards UniProt Show fit	cytokine inducible SH2-containing protein
chr3_+_50649302 Show fit	19.98	ENST00000446044.1	MAPKAPK3 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase-activated protein kinase 3
chr6_+_32605195 Show fit	19.32	ENST00000374949.2	HLA-DQA1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr2_-_89292422 Show fit	18.05	ENST00000495489.1	IGKV1-8 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-8
chr6_+_32407619 Show fit	16.62	ENST00000395388.2 ENST00000374982.5	HLA-DRA Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DR alpha
chr1_-_36937075 Show fit	16.34	ENST00000464465.2	CSF3R Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 3 receptor (granulocyte)
chr19_+_42724423 Show fit	16.25	ENST00000301215.3 ENST00000597945.1	ZNF526 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 526
chr2_-_89399845 Show fit	14.00	ENST00000479981.1	IGKV1-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-16
chr6_+_33048222 Show fit	13.89	ENST00000428835.1	HLA-DPB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DP beta 1
chr2_+_90198535 Show fit	13.30	ENST00000390276.2	IGKV1D-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-12
chr12_-_15114603 Show fit	12.98	ENST00000228945.4	ARHGDIB Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr1_+_158801095 Show fit	12.90	ENST00000368141.4	MNDA Links Ensembl NCBI GeneCards UniProt Show fit	myeloid cell nuclear differentiation antigen
chr4_-_71532339 Show fit	12.06	ENST00000254801.4	IGJ Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_-_15114492 Show fit	11.98	ENST00000541546.1	ARHGDIB Links Ensembl NCBI GeneCards UniProt Show fit	Rho GDP dissociation inhibitor (GDI) beta
chr1_-_36948879 Show fit	11.90	ENST00000373106.1 ENST00000373104.1 ENST00000373103.1	CSF3R Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 3 receptor (granulocyte)
chr17_-_76356148 Show fit	11.88	ENST00000587578.1 ENST00000330871.2	SOCS3 Links Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 3
chr1_+_111415757 Show fit	11.73	ENST00000429072.2 ENST00000271324.5	CD53 Links Ensembl NCBI GeneCards UniProt Show fit	CD53 molecule
chr2_+_90139056 Show fit	11.63	ENST00000492446.1	IGKV1D-16 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-16
chr1_+_233086326 Show fit	11.17	ENST00000366628.5 ENST00000366627.4	NTPCR Links Ensembl NCBI GeneCards UniProt Show fit	nucleoside-triphosphatase, cancer-related
chr22_+_23241661 Show fit	11.14	ENST00000390322.2	IGLJ2 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 2
chr6_+_31582961 Show fit	11.03	ENST00000376059.3 ENST00000337917.7	AIF1 Links Ensembl NCBI GeneCards UniProt Show fit	allograft inflammatory factor 1
chr19_-_10446449 Show fit	10.10	ENST00000592439.1	ICAM3 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr5_-_140013275 Show fit	9.91	ENST00000512545.1 ENST00000302014.6 ENST00000401743.2	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr1_-_159046617 Show fit	9.73	ENST00000368130.4	AIM2 Links Ensembl NCBI GeneCards UniProt Show fit	absent in melanoma 2
chr5_-_138725560 Show fit	9.66	ENST00000412103.2 ENST00000457570.2	MZB1 Links Ensembl NCBI GeneCards UniProt Show fit	marginal zone B and B1 cell-specific protein
chr5_-_138725594 Show fit	9.61	ENST00000302125.8	MZB1 Links Ensembl NCBI GeneCards UniProt Show fit	marginal zone B and B1 cell-specific protein
chrY_+_15016725 Show fit	9.60	ENST00000336079.3	DDX3Y Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr22_+_37257015 Show fit	9.53	ENST00000447071.1 ENST00000248899.6 ENST00000397147.4	NCF4 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 4, 40kDa
chr7_+_74188309 Show fit	9.50	ENST00000289473.4 ENST00000433458.1	NCF1 Links Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 1
chr2_-_89340242 Show fit	9.42	ENST00000480492.1	IGKV1-12 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1-12
chr19_+_18284477 Show fit	9.32	ENST00000407280.3	IFI30 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 30
chr17_+_40440481 Show fit	9.13	ENST00000590726.2 ENST00000452307.2 ENST00000444283.1 ENST00000588868.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr9_-_97402531 Show fit	9.08	ENST00000415431.1	FBP1 Links Ensembl NCBI GeneCards UniProt Show fit	fructose-1,6-bisphosphatase 1
chr19_-_44809121 Show fit	8.93	ENST00000591609.1 ENST00000589799.1 ENST00000291182.4 ENST00000589248.1	ZNF235 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 235
chr7_-_36634181 Show fit	8.86	ENST00000538464.1	AOAH Links Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr2_+_17935383 Show fit	8.74	ENST00000524465.1 ENST00000381254.2 ENST00000532257.1	GEN1 Links Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr17_-_34207295 Show fit	8.72	ENST00000463941.1 ENST00000293272.3	CCL5 Links Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 5
chr7_-_29186008 Show fit	8.72	ENST00000396276.3 ENST00000265394.5	CPVL Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase, vitellogenic-like
chr3_+_111260954 Show fit	8.68	ENST00000283285.5	CD96 Links Ensembl NCBI GeneCards UniProt Show fit	CD96 molecule
chr17_-_62084241 Show fit	8.63	ENST00000449662.2	ICAM2 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 2
chr10_-_75571341 Show fit	8.62	ENST00000309979.6	NDST2 Links Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_+_85804614 Show fit	8.61	ENST00000263864.5 ENST00000409760.1	VAMP8 Links Ensembl NCBI GeneCards UniProt Show fit	vesicle-associated membrane protein 8
chr1_+_158975744 Show fit	8.56	ENST00000426592.2	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr10_-_75571566 Show fit	8.52	ENST00000299641.4	NDST2 Links Ensembl NCBI GeneCards UniProt Show fit	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_-_175547571 Show fit	8.46	ENST00000409415.3 ENST00000359761.3 ENST00000272746.5	WIPF1 Links Ensembl NCBI GeneCards UniProt Show fit	WAS/WASL interacting protein family, member 1
chr7_+_80275621 Show fit	8.43	ENST00000426978.1 ENST00000432207.1	CD36 Links Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr22_+_23247030 Show fit	8.36	ENST00000390324.2	IGLJ3 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda joining 3
chr10_-_6622201 Show fit	8.36	ENST00000539722.1 ENST00000397176.2	PRKCQ Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C, theta
chr22_-_37640456 Show fit	8.27	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_37407212 Show fit	8.26	ENST00000427117.1 ENST00000587130.1 ENST00000333987.7 ENST00000415168.1 ENST00000444991.1	ZNF568 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 568
chr9_-_110251836 Show fit	8.25	ENST00000374672.4	KLF4 Links Ensembl NCBI GeneCards UniProt Show fit	Kruppel-like factor 4 (gut)
chr5_-_169694286 Show fit	8.25	ENST00000521416.1 ENST00000520344.1	LCP2 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr22_-_37640277 Show fit	8.23	ENST00000401529.3 ENST00000249071.6	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_-_6836156 Show fit	8.22	ENST00000382679.2	DEFA1 Links Ensembl NCBI GeneCards UniProt Show fit	defensin, alpha 1
chr6_+_32605134 Show fit	7.99	ENST00000343139.5 ENST00000395363.1 ENST00000496318.1	HLA-DQA1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ alpha 1
chr14_+_21249200 Show fit	7.71	ENST00000304677.2	RNASE6 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease, RNase A family, k6
chr9_-_97402413 Show fit	7.71	ENST00000414122.1	FBP1 Links Ensembl NCBI GeneCards UniProt Show fit	fructose-1,6-bisphosphatase 1
chr19_-_51875894 Show fit	7.66	ENST00000600427.1 ENST00000595217.1 ENST00000221978.5	NKG7 Links Ensembl NCBI GeneCards UniProt Show fit	natural killer cell group 7 sequence
chr7_-_37026108 Show fit	7.55	ENST00000396045.3	ELMO1 Links Ensembl NCBI GeneCards UniProt Show fit	engulfment and cell motility 1
chr17_-_29641084 Show fit	7.50	ENST00000544462.1	EVI2B Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr2_+_17935119 Show fit	7.50	ENST00000317402.7	GEN1 Links Ensembl NCBI GeneCards UniProt Show fit	GEN1 Holliday junction 5' flap endonuclease
chr16_-_75498308 Show fit	7.41	ENST00000569540.1	TMEM170A Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 170A
chrY_+_15016013 Show fit	7.40	ENST00000360160.4 ENST00000454054.1	DDX3Y Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr7_+_142829162 Show fit	7.34	ENST00000291009.3	PIP Links Ensembl NCBI GeneCards UniProt Show fit	prolactin-induced protein
chr22_-_38902300 Show fit	7.33	ENST00000403230.1	DDX17 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr19_+_1041212 Show fit	7.29	ENST00000433129.1	ABCA7 Links Ensembl NCBI GeneCards UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 7
chr2_+_163200848 Show fit	7.28	ENST00000233612.4	GCA Links Ensembl NCBI GeneCards UniProt Show fit	grancalcin, EF-hand calcium binding protein
chr12_+_32112340 Show fit	7.14	ENST00000540924.1 ENST00000312561.4	KIAA1551 Links Ensembl NCBI GeneCards UniProt Show fit	KIAA1551
chr11_-_10590238 Show fit	7.08	ENST00000256178.3	LYVE1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr6_-_32820529 Show fit	7.08	ENST00000425148.2	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_29641104 Show fit	7.06	ENST00000577894.1 ENST00000330927.4	EVI2B Links Ensembl NCBI GeneCards UniProt Show fit	ecotropic viral integration site 2B
chr14_-_25103388 Show fit	7.05	ENST00000526004.1 ENST00000415355.3	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr5_+_40909354 Show fit	7.05	ENST00000313164.9	C7 Links Ensembl NCBI GeneCards UniProt Show fit	complement component 7
chr2_+_90192768 Show fit	7.00	ENST00000390275.2	IGKV1D-13 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin kappa variable 1D-13
chr7_+_80275752 Show fit	7.00	ENST00000419819.2	CD36 Links Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr14_-_25103472 Show fit	6.98	ENST00000216341.4 ENST00000382542.1 ENST00000382540.1	GZMB Links Ensembl NCBI GeneCards UniProt Show fit	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_+_54704610 Show fit	6.80	ENST00000302907.4	RPS9 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S9
chr5_-_169725231 Show fit	6.79	ENST00000046794.5	LCP2 Links Ensembl NCBI GeneCards UniProt Show fit	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr13_-_46964177 Show fit	6.73	ENST00000389908.3	KIAA0226L Links Ensembl NCBI GeneCards UniProt Show fit	KIAA0226-like
chr11_-_615570 Show fit	6.61	ENST00000525445.1 ENST00000348655.6 ENST00000397566.1	IRF7 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 7
chr15_-_38856836 Show fit	6.61	ENST00000450598.2 ENST00000559830.1 ENST00000558164.1 ENST00000310803.5	RASGRP1 Links Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr1_-_161519579 Show fit	6.60	ENST00000426740.1	FCGR3A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr16_-_21663919 Show fit	6.56	ENST00000569602.1	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr1_+_158979792 Show fit	6.47	ENST00000359709.3 ENST00000430894.2	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr6_-_32634425 Show fit	6.42	ENST00000399082.3 ENST00000399079.3 ENST00000374943.4 ENST00000434651.2	HLA-DQB1 Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr12_-_54689532 Show fit	6.37	ENST00000540264.2 ENST00000312156.4	NFE2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2
chr7_+_117120017 Show fit	6.34	ENST00000003084.6 ENST00000454343.1	CFTR Links Ensembl NCBI GeneCards UniProt Show fit	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr12_-_117537240 Show fit	6.28	ENST00000392545.4 ENST00000541210.1 ENST00000335209.7	TESC Links Ensembl NCBI GeneCards UniProt Show fit	tescalcin
chr5_-_172198190 Show fit	6.22	ENST00000239223.3	DUSP1 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 1
chr11_+_117049910 Show fit	6.20	ENST00000431081.2 ENST00000524842.1	SIDT2 Links Ensembl NCBI GeneCards UniProt Show fit	SID1 transmembrane family, member 2
chr1_-_161600822 Show fit	6.17	ENST00000534776.1 ENST00000540048.1	FCGR3B Links Ensembl NCBI GeneCards UniProt Show fit FCGR3A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIb, receptor (CD16b) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_+_128563652 Show fit	6.16	ENST00000527786.2	FLI1 Links Ensembl NCBI GeneCards UniProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr19_+_55128576 Show fit	6.12	ENST00000396331.1	LILRB1 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr14_+_75988851 Show fit	6.03	ENST00000555504.1	BATF Links Ensembl NCBI GeneCards UniProt Show fit	basic leucine zipper transcription factor, ATF-like
chr14_+_61789382 Show fit	5.98	ENST00000555082.1	PRKCH Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C, eta
chr7_-_36764004 Show fit	5.88	ENST00000431169.1	AOAH Links Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr3_+_38179969 Show fit	5.87	ENST00000396334.3 ENST00000417037.2 ENST00000424893.1 ENST00000495303.1 ENST00000443433.2 ENST00000421516.1	MYD88 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid differentiation primary response 88
chr16_-_20338748 Show fit	5.77	ENST00000575582.1 ENST00000341642.5 ENST00000381362.4 ENST00000572347.1 ENST00000572478.1 ENST00000302555.5	GP2 Links Ensembl NCBI GeneCards UniProt Show fit	glycoprotein 2 (zymogen granule membrane)
chr7_+_139529040 Show fit	5.74	ENST00000455353.1 ENST00000458722.1 ENST00000411653.1	TBXAS1 Links Ensembl NCBI GeneCards UniProt Show fit	thromboxane A synthase 1 (platelet)
chr1_+_158979680 Show fit	5.72	ENST00000368131.4 ENST00000340979.6	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr22_-_24096562 Show fit	5.71	ENST00000398465.3	VPREB3 Links Ensembl NCBI GeneCards UniProt Show fit	pre-B lymphocyte 3
chr6_+_144471643 Show fit	5.70	ENST00000367568.4	STX11 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 11
chr19_-_40023450 Show fit	5.67	ENST00000326282.4	EID2B Links Ensembl NCBI GeneCards UniProt Show fit	EP300 interacting inhibitor of differentiation 2B
chr17_+_77681075 Show fit	5.63	ENST00000397549.2	CTD-2116F7.1 Links Ensembl NCBI GeneCards UniProt Show fit	CTD-2116F7.1
chr22_-_38902325 Show fit	5.62	ENST00000396821.3 ENST00000381633.3	DDX17 Links Ensembl NCBI GeneCards UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr13_+_111767650 Show fit	5.62	ENST00000449979.1 ENST00000370623.3	ARHGEF7 Links Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_53468332 Show fit	5.60	ENST00000262133.6	RBL2 Links Ensembl NCBI GeneCards UniProt Show fit	retinoblastoma-like 2 (p130)
chr20_-_43280361 Show fit	5.58	ENST00000372874.4	ADA Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase
chr1_-_161600990 Show fit	5.58	ENST00000531221.1	FCGR3B Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_40324767 Show fit	5.47	ENST00000601972.1 ENST00000430012.2 ENST00000323039.5 ENST00000348817.3	DYRK1B Links Ensembl NCBI GeneCards UniProt Show fit	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_+_55361898 Show fit	5.45	ENST00000326321.3 ENST00000270442.5	KIR3DL2 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
chr1_+_158979686 Show fit	5.44	ENST00000368132.3 ENST00000295809.7	IFI16 Links Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma-inducible protein 16
chr12_+_56324756 Show fit	5.42	ENST00000331886.5 ENST00000555090.1	DGKA Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase, alpha 80kDa
chr21_+_34602377 Show fit	5.39	ENST00000342101.3 ENST00000413881.1 ENST00000443073.1	IFNAR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon (alpha, beta and omega) receptor 2
chr1_-_161600942 Show fit	5.38	ENST00000421702.2	FCGR3B Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr19_-_59084647 Show fit	5.32	ENST00000594234.1 ENST00000596039.1	MZF1 Links Ensembl NCBI GeneCards UniProt Show fit	myeloid zinc finger 1
chr11_-_10590118 Show fit	5.30	ENST00000529598.1	LYVE1 Links Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_161519682 Show fit	5.27	ENST00000367969.3 ENST00000443193.1	FCGR3A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr5_+_137225158 Show fit	5.26	ENST00000290431.5	PKD2L2 Links Ensembl NCBI GeneCards UniProt Show fit	polycystic kidney disease 2-like 2
chr10_-_6019552 Show fit	5.21	ENST00000379977.3 ENST00000397251.3 ENST00000397248.2	IL15RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor, alpha
chr17_-_80408569 Show fit	5.20	ENST00000577696.1 ENST00000577471.1 ENST00000582545.2 ENST00000437807.2 ENST00000583617.1 ENST00000578913.1 ENST00000336995.7 ENST00000577834.1 ENST00000342572.8 ENST00000585064.1 ENST00000585080.1 ENST00000578919.1 ENST00000306645.5 ENST00000434650.2	C17orf62 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 17 open reading frame 62
chr7_+_139528952 Show fit	5.18	ENST00000416849.2 ENST00000436047.2 ENST00000414508.2 ENST00000448866.1	TBXAS1 Links Ensembl NCBI GeneCards UniProt Show fit	thromboxane A synthase 1 (platelet)
chr19_+_51728316 Show fit	5.10	ENST00000436584.2 ENST00000421133.2 ENST00000391796.3 ENST00000262262.4	CD33 Links Ensembl NCBI GeneCards UniProt Show fit	CD33 molecule
chr13_-_33112956 Show fit	5.06	ENST00000505213.1	N4BP2L2 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD4 binding protein 2-like 2
chr21_+_34602200 Show fit	5.04	ENST00000382264.3 ENST00000382241.3 ENST00000404220.3 ENST00000342136.4	IFNAR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon (alpha, beta and omega) receptor 2
chr15_+_58430567 Show fit	5.03	ENST00000536493.1	AQP9 Links Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr8_+_104427581 Show fit	5.01	ENST00000521716.1 ENST00000521971.1 ENST00000519682.1	DCAF13 Links Ensembl NCBI GeneCards UniProt Show fit	DDB1 and CUL4 associated factor 13
chr19_+_52264104 Show fit	4.98	ENST00000340023.6	FPR2 Links Ensembl NCBI GeneCards UniProt Show fit	formyl peptide receptor 2
chr6_-_39693111 Show fit	4.97	ENST00000373215.3 ENST00000538893.1 ENST00000287152.7 ENST00000373216.3	KIF6 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 6
chr6_-_137539651 Show fit	4.97	ENST00000543628.1	IFNGR1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 1
chr17_-_40021656 Show fit	4.88	ENST00000319121.3	KLHL11 Links Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 11
chr17_-_76124711 Show fit	4.83	ENST00000306591.7 ENST00000590602.1	TMC6 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel-like 6
chr15_-_64648273 Show fit	4.83	ENST00000607537.1 ENST00000303052.7 ENST00000303032.6	CSNK1G1 Links Ensembl NCBI GeneCards UniProt Show fit	casein kinase 1, gamma 1
chr17_-_27224621 Show fit	4.82	ENST00000394906.2 ENST00000585169.1 ENST00000394908.4	FLOT2 Links Ensembl NCBI GeneCards UniProt Show fit	flotillin 2
chr15_-_73076030 Show fit	4.82	ENST00000311669.8	ADPGK Links Ensembl NCBI GeneCards UniProt Show fit	ADP-dependent glucokinase
chr3_+_111260856 Show fit	4.81	ENST00000352690.4	CD96 Links Ensembl NCBI GeneCards UniProt Show fit	CD96 molecule
chr5_-_180236811 Show fit	4.80	ENST00000446023.2	MGAT1 Links Ensembl NCBI GeneCards UniProt Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_-_56727487 Show fit	4.77	ENST00000548043.1 ENST00000425394.2	PAN2 Links Ensembl NCBI GeneCards UniProt Show fit	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_65253506 Show fit	4.76	ENST00000427538.1	VSIG4 Links Ensembl NCBI GeneCards UniProt Show fit	V-set and immunoglobulin domain containing 4
chr5_+_150400124 Show fit	4.76	ENST00000388825.4 ENST00000521650.1 ENST00000517973.1	GPX3 Links Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 3 (plasma)
chr6_+_131894284 Show fit	4.72	ENST00000368087.3 ENST00000356962.2	ARG1 Links Ensembl NCBI GeneCards UniProt Show fit	arginase 1
chr1_-_25558984 Show fit	4.72	ENST00000236273.4	SYF2 Links Ensembl NCBI GeneCards UniProt Show fit	SYF2 pre-mRNA-splicing factor
chr19_-_50529193 Show fit	4.72	ENST00000596445.1 ENST00000599538.1	VRK3 Links Ensembl NCBI GeneCards UniProt Show fit	vaccinia related kinase 3
chrY_+_22737604 Show fit	4.72	ENST00000361365.2	EIF1AY Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A, Y-linked
chr19_+_44617511 Show fit	4.71	ENST00000262894.6 ENST00000588926.1 ENST00000592780.1	ZNF225 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 225
chr10_+_30722866 Show fit	4.67	ENST00000263056.1	MAP3K8 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr9_-_88356733 Show fit	4.64	ENST00000376083.3	AGTPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein 1
chr19_+_10197463 Show fit	4.59	ENST00000590378.1 ENST00000397881.3	C19orf66 Links Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 66
chr4_+_128651530 Show fit	4.58	ENST00000281154.4	SLC25A31 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr16_-_21663950 Show fit	4.58	ENST00000268389.4	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 6
chr14_+_95078714 Show fit	4.57	ENST00000393078.3 ENST00000393080.4 ENST00000467132.1	SERPINA3 Links Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr6_-_41703952 Show fit	4.57	ENST00000358871.2 ENST00000403298.4	TFEB Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EB
chr19_+_55327923 Show fit	4.57	ENST00000391728.4 ENST00000326542.7 ENST00000358178.4	KIR3DL1 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr7_-_76829125 Show fit	4.56	ENST00000248598.5	FGL2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen-like 2
chrX_+_122993657 Show fit	4.45	ENST00000434753.3 ENST00000430625.1	XIAP Links Ensembl NCBI GeneCards UniProt Show fit	X-linked inhibitor of apoptosis
chr12_-_56727676 Show fit	4.43	ENST00000547572.1 ENST00000257931.5 ENST00000440411.3	PAN2 Links Ensembl NCBI GeneCards UniProt Show fit	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr10_-_72362515 Show fit	4.42	ENST00000373209.2 ENST00000441259.1	PRF1 Links Ensembl NCBI GeneCards UniProt Show fit	perforin 1 (pore forming protein)
chr11_-_22851367 Show fit	4.35	ENST00000354193.4	SVIP Links Ensembl NCBI GeneCards UniProt Show fit	small VCP/p97-interacting protein
chr1_+_158325684 Show fit	4.34	ENST00000368162.2	CD1E Links Ensembl NCBI GeneCards UniProt Show fit	CD1e molecule
chr11_-_59383617 Show fit	4.33	ENST00000263847.1	OSBP Links Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein
chr13_-_99959641 Show fit	4.32	ENST00000376414.4	GPR183 Links Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 183
chr5_-_64777733 Show fit	4.31	ENST00000381055.3	ADAMTS6 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_+_26727125 Show fit	4.27	ENST00000376236.4	APBB1IP Links Ensembl NCBI GeneCards UniProt Show fit	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr11_+_121461097 Show fit	4.25	ENST00000527934.1	SORL1 Links Ensembl NCBI GeneCards UniProt Show fit	sortilin-related receptor, L(DLR class) A repeats containing
chr13_-_33112899 Show fit	4.23	ENST00000267068.3 ENST00000357505.6 ENST00000399396.3	N4BP2L2 Links Ensembl NCBI GeneCards UniProt Show fit	NEDD4 binding protein 2-like 2
chr16_+_27413483 Show fit	4.22	ENST00000337929.3 ENST00000564089.1	IL21R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 21 receptor
chr22_-_24096630 Show fit	4.20	ENST00000248948.3	VPREB3 Links Ensembl NCBI GeneCards UniProt Show fit	pre-B lymphocyte 3
chr6_+_35995552 Show fit	4.17	ENST00000468133.1	MAPK14 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 14
chr22_+_22936998 Show fit	4.16	ENST00000390303.2	IGLV3-32 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-32 (non-functional)
chr4_+_87856129 Show fit	4.15	ENST00000395146.4 ENST00000507468.1	AFF1 Links Ensembl NCBI GeneCards UniProt Show fit	AF4/FMR2 family, member 1
chr16_-_1661988 Show fit	4.14	ENST00000426508.2	IFT140 Links Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 140 homolog (Chlamydomonas)
chr3_+_101443476 Show fit	4.14	ENST00000327230.4 ENST00000494050.1	CEP97 Links Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 97kDa
chr4_-_38806404 Show fit	4.12	ENST00000308979.2 ENST00000505940.1 ENST00000515861.1	TLR1 Links Ensembl NCBI GeneCards UniProt Show fit	toll-like receptor 1
chr20_+_16729003 Show fit	4.12	ENST00000246081.2	OTOR Links Ensembl NCBI GeneCards UniProt Show fit	otoraplin
chr9_-_88356789 Show fit	4.10	ENST00000357081.3 ENST00000376081.4 ENST00000337006.4 ENST00000376109.3	AGTPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein 1
chr19_+_54705025 Show fit	4.10	ENST00000441429.1	RPS9 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S9
chr15_-_86338134 Show fit	4.10	ENST00000337975.5	KLHL25 Links Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 25
chr17_+_75123947 Show fit	4.08	ENST00000586429.1	SEC14L1 Links Ensembl NCBI GeneCards UniProt Show fit	SEC14-like 1 (S. cerevisiae)
chr12_+_56324933 Show fit	4.08	ENST00000549629.1 ENST00000555218.1	DGKA Links Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase, alpha 80kDa
chr1_+_36690011 Show fit	4.07	ENST00000354618.5 ENST00000469141.2 ENST00000478853.1	THRAP3 Links Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor associated protein 3
chr8_+_95565947 Show fit	4.07	ENST00000523011.1	RP11-267M23.4 Links Ensembl NCBI GeneCards UniProt Show fit	RP11-267M23.4
chr13_-_45915221 Show fit	4.07	ENST00000309246.5 ENST00000379060.4 ENST00000379055.1 ENST00000527226.1 ENST00000379056.1	TPT1 Links Ensembl NCBI GeneCards UniProt Show fit	tumor protein, translationally-controlled 1
chr4_+_15779901 Show fit	4.06	ENST00000226279.3	CD38 Links Ensembl NCBI GeneCards UniProt Show fit	CD38 molecule
chr5_+_137225125 Show fit	4.05	ENST00000350250.4 ENST00000508638.1 ENST00000502810.1 ENST00000508883.1	PKD2L2 Links Ensembl NCBI GeneCards UniProt Show fit	polycystic kidney disease 2-like 2
chr16_+_67198683 Show fit	4.04	ENST00000517685.1 ENST00000521374.1 ENST00000584272.1	HSF4 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock transcription factor 4
chr1_+_12123414 Show fit	4.04	ENST00000263932.2	TNFRSF8 Links Ensembl NCBI GeneCards UniProt Show fit	tumor necrosis factor receptor superfamily, member 8
chr12_+_93964746 Show fit	4.04	ENST00000536696.2	SOCS2 Links Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chr19_+_55281260 Show fit	4.03	ENST00000336077.6 ENST00000291633.7	KIR2DL1 Links Ensembl NCBI GeneCards UniProt Show fit	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr8_-_56685966 Show fit	3.99	ENST00000334667.2	TMEM68 Links Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 68
chr1_+_149754227 Show fit	3.98	ENST00000444948.1 ENST00000369168.4	FCGR1A Links Ensembl NCBI GeneCards UniProt Show fit	Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr7_+_117120106 Show fit	3.96	ENST00000426809.1	CFTR Links Ensembl NCBI GeneCards UniProt Show fit	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr6_+_20534672 Show fit	3.94	ENST00000274695.4 ENST00000378624.4	CDKAL1 Links Ensembl NCBI GeneCards UniProt Show fit	CDK5 regulatory subunit associated protein 1-like 1
chr9_-_89562104 Show fit	3.94	ENST00000298743.7	GAS1 Links Ensembl NCBI GeneCards UniProt Show fit	growth arrest-specific 1
chr8_+_27168988 Show fit	3.94	ENST00000397501.1 ENST00000338238.4 ENST00000544172.1	PTK2B Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine kinase 2 beta
chrY_+_22737678 Show fit	3.94	ENST00000382772.3	EIF1AY Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1A, Y-linked
chr4_-_40517984 Show fit	3.94	ENST00000381795.6	RBM47 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 47
chrX_+_15767971 Show fit	3.93	ENST00000479740.1 ENST00000454127.2	CA5B Links Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase VB, mitochondrial
chr15_-_75660919 Show fit	3.91	ENST00000569482.1 ENST00000565683.1 ENST00000561615.1 ENST00000563622.1 ENST00000568374.1 ENST00000566256.1 ENST00000267978.5	MAN2C1 Links Ensembl NCBI GeneCards UniProt Show fit	mannosidase, alpha, class 2C, member 1
chr4_-_185395672 Show fit	3.90	ENST00000393593.3	IRF2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.6	46.4	GO:0071461	cellular response to redox state(GO:0071461)
5.5	16.4	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
5.4	16.2	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
4.5	17.9	GO:0071725	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
4.2	16.8	GO:0005986	sucrose biosynthetic process(GO:0005986)
4.2	16.6	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
3.9	19.3	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
3.9	19.3	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.6	18.1	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
3.4	10.3	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
3.1	9.3	GO:0046102	hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
2.9	8.7	GO:0035610	protein side chain deglutamylation(GO:0035610)
2.9	17.4	GO:0045903	positive regulation of translational fidelity(GO:0045903)
2.7	8.2	GO:0035915	pore formation in membrane of other organism(GO:0035915)
2.6	15.4	GO:0071724	toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
2.5	20.0	GO:0044351	macropinocytosis(GO:0044351)
2.4	7.3	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
2.3	9.1	GO:0000255	allantoin metabolic process(GO:0000255)
2.3	11.4	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
2.1	12.8	GO:0070269	pyroptosis(GO:0070269)
2.1	8.4	GO:0035712	T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
2.1	6.2	GO:0044278	cell wall disruption in other organism(GO:0044278)
2.0	6.1	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
2.0	6.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
2.0	14.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.0	2.0	GO:0006544	glycine metabolic process(GO:0006544)
1.8	7.4	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.8	7.1	GO:0046967	cytosol to ER transport(GO:0046967)
1.8	10.6	GO:0016554	cytidine to uridine editing(GO:0016554)
1.6	4.8	GO:0006982	response to lipid hydroperoxide(GO:0006982)
1.5	6.1	GO:2001193	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
1.5	4.4	GO:1902530	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.5	4.4	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
1.5	4.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.4	10.1	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
1.4	4.3	GO:0061470	T follicular helper cell differentiation(GO:0061470)
1.4	10.0	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.4	4.2	GO:1905246	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.4	15.1	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
1.3	4.0	GO:0032679	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
1.3	3.9	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752)
1.3	3.9	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
1.3	28.2	GO:0097186	amelogenesis(GO:0097186)
1.3	3.8	GO:1903413	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
1.2	6.1	GO:0015722	canalicular bile acid transport(GO:0015722)
1.2	3.6	GO:1904425	negative regulation of GTP binding(GO:1904425)
1.2	4.8	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
1.2	5.9	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
1.1	3.4	GO:1904604	regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.1	6.6	GO:0032252	secretory granule localization(GO:0032252)
1.1	3.3	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731)
1.1	3.3	GO:0038178	complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.1	2.2	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
1.1	12.7	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
1.1	3.2	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.0	3.1	GO:0045062	extrathymic T cell selection(GO:0045062)
1.0	6.1	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
1.0	4.0	GO:0002767	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.0	3.0	GO:0097254	renal tubular secretion(GO:0097254)
1.0	8.9	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
1.0	2.0	GO:2000977	regulation of forebrain neuron differentiation(GO:2000977)
0.9	4.7	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.9	2.8	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.9	1.8	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.9	3.5	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.9	6.2	GO:0033227	dsRNA transport(GO:0033227)
0.9	2.6	GO:0002125	maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.9	2.6	GO:1990637	response to prolactin(GO:1990637)
0.9	3.5	GO:0003335	corneocyte development(GO:0003335)
0.8	6.6	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.8	5.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.8	5.6	GO:0008218	bioluminescence(GO:0008218)
0.8	19.0	GO:0045730	respiratory burst(GO:0045730)
0.8	3.2	GO:0036337	Fas signaling pathway(GO:0036337)
0.8	2.3	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.8	7.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.8	2.3	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.8	3.0	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.7	6.0	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.7	2.2	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.7	2.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.7	6.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.7	2.2	GO:0019556	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.7	1.4	GO:0002436	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.7	29.9	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.7	3.5	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.7	13.4	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.7	2.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.7	11.7	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.7	2.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.7	2.1	GO:0006710	androgen catabolic process(GO:0006710)
0.7	2.7	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.7	17.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.7	2.0	GO:0046968	peptide antigen transport(GO:0046968)
0.7	25.6	GO:1900077	negative regulation of cellular response to insulin stimulus(GO:1900077)
0.7	2.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.6	2.6	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.6	84.0	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.6	1.3	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.6	11.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.6	4.3	GO:0044126	regulation of growth of symbiont in host(GO:0044126)
0.6	3.7	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.6	10.9	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.6	3.0	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.6	5.3	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6	2.3	GO:0042713	sperm ejaculation(GO:0042713)
0.6	12.9	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.6	8.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.6	1.7	GO:0003099	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.6	4.5	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.6	2.8	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6	5.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.5	3.2	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.5	1.1	GO:0002329	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.5	2.7	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.5	5.3	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.5	1.6	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.5	2.1	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.5	1.6	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.5	1.6	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5	3.6	GO:0075044	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.5	1.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.5	3.6	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.5	2.6	GO:0010587	miRNA catabolic process(GO:0010587)
0.5	2.0	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.5	2.5	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.5	5.4	GO:0002418	immune response to tumor cell(GO:0002418)
0.5	1.5	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.5	85.9	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.5	3.9	GO:0006013	mannose metabolic process(GO:0006013)
0.5	1.5	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
0.5	1.5	GO:0006014	D-ribose metabolic process(GO:0006014)
0.5	1.9	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5	1.9	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.5	1.9	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.5	11.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.5	1.9	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.5	2.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.5	4.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.4	9.9	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.4	3.6	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.4	1.8	GO:0070475	rRNA base methylation(GO:0070475)
0.4	6.0	GO:0042832	defense response to protozoan(GO:0042832)
0.4	1.7	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.4	2.6	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.4	1.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.4	6.0	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4	3.8	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.4	2.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.4	6.2	GO:1903504	peptidyl-threonine dephosphorylation(GO:0035970) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.4	4.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.4	4.9	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4	2.4	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.4	1.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4	11.1	GO:0007520	myoblast fusion(GO:0007520)
0.4	3.2	GO:0006600	creatine metabolic process(GO:0006600)
0.4	0.8	GO:0046110	xanthine metabolic process(GO:0046110)
0.4	1.9	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4	6.2	GO:0035855	megakaryocyte development(GO:0035855)
0.4	4.1	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.4	1.1	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.4	3.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.4	3.0	GO:0007288	acrosome assembly(GO:0001675) sperm axoneme assembly(GO:0007288)
0.4	8.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.4	17.0	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.4	2.1	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.4	1.8	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4	1.4	GO:1902202	regulation of endothelial tube morphogenesis(GO:1901509) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4	2.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.3	1.0	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3	6.1	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.3	2.0	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) response to oleic acid(GO:0034201)
0.3	1.3	GO:0071321	cellular response to cGMP(GO:0071321)
0.3	2.9	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.3	1.0	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.3	4.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3	1.9	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3	19.5	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.3	2.7	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.3	8.2	GO:0019731	antibacterial humoral response(GO:0019731)
0.3	5.7	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3	1.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.3	0.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.3	2.5	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.3	1.7	GO:0018879	biphenyl metabolic process(GO:0018879)
0.3	8.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.3	1.1	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.3	0.5	GO:0071109	superior temporal gyrus development(GO:0071109)
0.3	5.0	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.3	1.8	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.3	1.8	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.3	1.5	GO:0060235	embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.3	1.5	GO:0019530	taurine metabolic process(GO:0019530)
0.3	9.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2	1.5	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	3.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	2.0	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.2	3.5	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2	6.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	4.1	GO:0001502	cartilage condensation(GO:0001502)
0.2	2.6	GO:0006702	androgen biosynthetic process(GO:0006702)
0.2	1.4	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	1.8	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2	2.5	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2	3.2	GO:0051546	keratinocyte migration(GO:0051546)
0.2	4.1	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.2	0.7	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.2	2.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.2	2.7	GO:0070307	lens fiber cell development(GO:0070307)
0.2	7.3	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.2	1.8	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	2.9	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2	7.7	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.2	13.3	GO:0045576	mast cell activation(GO:0045576)
0.2	2.6	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.2	1.1	GO:0015747	urate transport(GO:0015747)
0.2	3.4	GO:0048266	behavioral response to pain(GO:0048266)
0.2	1.7	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.2	0.8	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.2	3.1	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.2	4.0	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.2	1.7	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.2	0.8	GO:1903012	positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.2	4.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.2	1.1	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.2	2.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	1.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.2	1.8	GO:0006265	DNA topological change(GO:0006265)
0.2	1.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.2	1.4	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.2	0.5	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.2	8.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.2	1.0	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2	0.5	GO:0042938	dipeptide transport(GO:0042938)
0.2	3.7	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2	2.1	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.2	0.8	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.2	1.7	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.2	3.0	GO:0019835	cytolysis(GO:0019835)
0.2	2.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.2	0.3	GO:0016240	autophagosome docking(GO:0016240)
0.2	4.2	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.2	0.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	3.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.4	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	1.9	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	2.4	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	1.6	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	4.6	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	1.4	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.8	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	8.4	GO:0031295	T cell costimulation(GO:0031295)
0.1	0.3	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	1.1	GO:0015705	iodide transport(GO:0015705)
0.1	5.0	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	7.3	GO:0006968	cellular defense response(GO:0006968)
0.1	4.7	GO:0006953	acute-phase response(GO:0006953)
0.1	0.4	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	1.5	GO:0048484	enteric nervous system development(GO:0048484)
0.1	1.5	GO:0007512	adult heart development(GO:0007512)
0.1	1.4	GO:0000187	activation of MAPK activity(GO:0000187)
0.1	1.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.1	14.4	GO:0002377	immunoglobulin production(GO:0002377)
0.1	4.8	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	5.7	GO:0015701	bicarbonate transport(GO:0015701)
0.1	4.3	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	1.5	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	1.0	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	1.9	GO:0010447	response to acidic pH(GO:0010447)
0.1	5.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1	2.7	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	1.3	GO:0032620	interleukin-17 production(GO:0032620)
0.1	0.9	GO:1903799	antral ovarian follicle growth(GO:0001547) vagina development(GO:0060068) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.5	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.8	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1	0.4	GO:0072143	renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	3.6	GO:0030101	natural killer cell activation(GO:0030101)
0.1	1.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	0.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	1.4	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	1.4	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	1.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	1.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	1.4	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.1	1.2	GO:0050832	defense response to fungus(GO:0050832)
0.1	4.3	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	1.8	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.1	1.1	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	1.9	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	3.6	GO:0046849	bone remodeling(GO:0046849)
0.1	1.0	GO:0070831	basement membrane assembly(GO:0070831)
0.1	3.9	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1	3.1	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	2.2	GO:0046688	response to copper ion(GO:0046688)
0.1	3.3	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.1	0.6	GO:1903358	regulation of Golgi organization(GO:1903358)
0.1	0.6	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.9	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.5	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
0.1	1.2	GO:0045807	positive regulation of endocytosis(GO:0045807)
0.1	1.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.8	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.1	4.9	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.1	1.0	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	3.3	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	2.6	GO:0034332	adherens junction organization(GO:0034332)
0.1	2.5	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1	0.3	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1	1.8	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.4	GO:0002027	regulation of heart rate(GO:0002027)
0.1	0.9	GO:0009299	mRNA transcription(GO:0009299)
0.1	1.1	GO:0060349	bone morphogenesis(GO:0060349)
0.1	0.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	1.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	1.6	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.1	1.6	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	0.4	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	1.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.1	1.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.1	1.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.1	1.9	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	1.8	GO:0006612	protein targeting to membrane(GO:0006612)
0.1	0.8	GO:0017145	stem cell division(GO:0017145)
0.1	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	1.7	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.1	1.4	GO:0031214	biomineral tissue development(GO:0031214)
0.0	2.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.6	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.8	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.2	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.8	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	2.3	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.3	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.5	GO:0009404	toxin metabolic process(GO:0009404)
0.0	4.0	GO:0006954	inflammatory response(GO:0006954)
0.0	1.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	1.1	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	2.5	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	1.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	4.5	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.2	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.9	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	1.0	GO:0060147	regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966)
0.0	0.6	GO:0060325	face morphogenesis(GO:0060325)
0.0	4.6	GO:0030509	BMP signaling pathway(GO:0030509)
0.0	0.7	GO:0030728	ovulation(GO:0030728)
0.0	0.7	GO:0097178	ruffle assembly(GO:0097178)
0.0	1.0	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.3	GO:0001570	vasculogenesis(GO:0001570)
0.0	0.5	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.7	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.9	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.7	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.7	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0	2.3	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	1.0	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	0.5	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.0	0.1	GO:0001507	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0	1.3	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.9	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.6	GO:0007265	Ras protein signal transduction(GO:0007265)
0.0	0.5	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.6	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	1.6	GO:0007098	centrosome cycle(GO:0007098)
0.0	0.2	GO:0016486	peptide hormone processing(GO:0016486)
0.0	2.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.8	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.3	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.0	0.2	GO:0032570	response to progesterone(GO:0032570)
0.0	0.5	GO:0030317	sperm motility(GO:0030317)
0.0	0.2	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.2	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	1.6	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	70.1	GO:0042613	MHC class II protein complex(GO:0042613)
3.1	9.2	GO:0031251	PAN complex(GO:0031251)
3.1	15.3	GO:0036398	TCR signalosome(GO:0036398)
2.7	8.0	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.4	19.0	GO:0032010	phagolysosome(GO:0032010)
2.1	16.6	GO:0097169	AIM2 inflammasome complex(GO:0097169)
2.1	10.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
1.9	9.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.4	12.8	GO:0005579	membrane attack complex(GO:0005579)
1.2	5.0	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.2	7.1	GO:0042825	TAP complex(GO:0042825)
1.1	9.5	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.0	3.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.0	19.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.9	12.2	GO:0005577	fibrinogen complex(GO:0005577)
0.9	3.7	GO:0097224	sperm connecting piece(GO:0097224)
0.8	4.1	GO:0045298	tubulin complex(GO:0045298)
0.8	3.0	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.7	14.5	GO:0001891	phagocytic cup(GO:0001891)
0.7	5.6	GO:0000322	storage vacuole(GO:0000322)
0.7	4.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.7	13.5	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6	4.4	GO:0044194	cytolytic granule(GO:0044194)
0.6	7.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.6	10.9	GO:0031089	platelet dense granule lumen(GO:0031089)
0.6	1.8	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.6	12.7	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.6	2.8	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.5	28.9	GO:0001772	immunological synapse(GO:0001772)
0.5	5.8	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.5	3.8	GO:0045179	apical cortex(GO:0045179)
0.5	2.8	GO:1990769	proximal neuron projection(GO:1990769)
0.5	6.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.4	1.3	GO:0042612	MHC class I protein complex(GO:0042612)
0.4	1.7	GO:0005606	laminin-1 complex(GO:0005606)
0.4	2.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.4	3.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.4	1.2	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.4	11.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.4	1.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.3	1.0	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.3	2.1	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.3	12.5	GO:0016592	mediator complex(GO:0016592)
0.3	4.3	GO:0042101	T cell receptor complex(GO:0042101)
0.3	4.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	9.6	GO:0042629	mast cell granule(GO:0042629)
0.3	2.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3	3.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.3	3.6	GO:0097524	sperm plasma membrane(GO:0097524)
0.3	5.6	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.3	19.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.3	1.9	GO:0097165	nuclear stress granule(GO:0097165)
0.3	3.2	GO:0001741	XY body(GO:0001741)
0.3	0.5	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.3	2.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.3	0.8	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.3	3.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	0.5	GO:0030314	junctional membrane complex(GO:0030314)
0.2	3.9	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.2	12.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.2	27.0	GO:0031225	anchored component of membrane(GO:0031225)
0.2	6.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	0.8	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	18.4	GO:0070821	tertiary granule membrane(GO:0070821)
0.2	8.3	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	14.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	5.7	GO:0031201	SNARE complex(GO:0031201)
0.2	1.4	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.2	9.8	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.2	2.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.2	17.4	GO:0035578	azurophil granule lumen(GO:0035578)
0.2	2.7	GO:0042588	zymogen granule(GO:0042588)
0.2	8.2	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	4.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.2	1.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.2	5.0	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	1.0	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1	5.4	GO:0005859	muscle myosin complex(GO:0005859)
0.1	2.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	3.9	GO:0005682	U5 snRNP(GO:0005682)
0.1	1.5	GO:0005922	connexon complex(GO:0005922)
0.1	1.9	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	6.1	GO:0001533	cornified envelope(GO:0001533)
0.1	1.1	GO:0000800	lateral element(GO:0000800)
0.1	5.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	3.4	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.1	12.9	GO:0016605	PML body(GO:0016605)
0.1	0.7	GO:0061700	GATOR2 complex(GO:0061700)
0.1	4.1	GO:0031904	endosome lumen(GO:0031904)
0.1	2.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	5.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	17.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.8	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	6.3	GO:0005796	Golgi lumen(GO:0005796)
0.1	9.7	GO:0043202	lysosomal lumen(GO:0043202)
0.1	2.8	GO:0008180	COP9 signalosome(GO:0008180)
0.1	2.5	GO:0035869	ciliary transition zone(GO:0035869)
0.1	3.3	GO:0009925	basal plasma membrane(GO:0009925)
0.1	5.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	5.4	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	33.5	GO:0016607	nuclear speck(GO:0016607)
0.1	2.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.9	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	7.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	0.7	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	2.8	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	0.8	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	5.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	103.6	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	0.9	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	1.1	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	1.0	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	2.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.4	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.8	GO:0005901	caveola(GO:0005901)
0.0	3.9	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	3.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	2.8	GO:0001726	ruffle(GO:0001726)
0.0	38.8	GO:0005615	extracellular space(GO:0005615)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	2.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	4.1	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	1.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.6	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.2	GO:0031105	septin complex(GO:0031105)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	28.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
4.9	14.7	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
4.6	46.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
4.2	16.8	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
4.0	56.2	GO:0032395	MHC class II receptor activity(GO:0032395)
3.7	11.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
3.6	10.9	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
3.4	10.3	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
3.4	17.0	GO:0004905	type I interferon receptor activity(GO:0004905)
3.3	9.9	GO:0016019	peptidoglycan receptor activity(GO:0016019)
3.2	12.7	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
2.7	8.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
2.6	15.4	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
2.4	7.3	GO:0034188	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.4	43.0	GO:0019864	IgG binding(GO:0019864)
2.3	13.8	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
2.2	17.4	GO:1990932	5.8S rRNA binding(GO:1990932)
2.1	6.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
2.0	16.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
1.9	19.0	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.7	8.3	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.4	4.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
1.3	6.6	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
1.3	3.9	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.3	5.0	GO:0015254	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
1.2	3.7	GO:0005148	prolactin receptor binding(GO:0005148)
1.2	8.6	GO:0008142	oxysterol binding(GO:0008142)
1.2	4.8	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.2	6.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
1.2	7.1	GO:0046979	TAP2 binding(GO:0046979)
1.2	7.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.2	9.3	GO:0004000	adenosine deaminase activity(GO:0004000)
1.1	3.4	GO:1904599	advanced glycation end-product binding(GO:1904599)
1.1	6.8	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
1.1	5.5	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.1	4.4	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
1.1	3.3	GO:0004878	complement component C5a receptor activity(GO:0004878)
1.1	20.0	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0	11.4	GO:0051525	NFAT protein binding(GO:0051525)
1.0	3.1	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
1.0	11.0	GO:0042834	peptidoglycan binding(GO:0042834)
1.0	5.0	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.9	5.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.9	2.6	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.7	3.0	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.7	15.9	GO:0042605	peptide antigen binding(GO:0042605)
0.7	2.7	GO:1904493	Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.7	4.1	GO:0039552	RIG-I binding(GO:0039552)
0.7	2.0	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.7	8.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.7	2.7	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.6	11.0	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.6	3.2	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.6	1.8	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.6	4.9	GO:0034235	GPI anchor binding(GO:0034235)
0.6	7.3	GO:0050700	CARD domain binding(GO:0050700)
0.6	1.8	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.6	1.7	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.6	1.7	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.5	9.9	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.5	2.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.5	8.7	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.5	2.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.5	3.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5	1.6	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5	8.4	GO:0004697	protein kinase C activity(GO:0004697)
0.5	1.5	GO:0047325	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.5	9.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.5	1.5	GO:0030145	manganese ion binding(GO:0030145)
0.5	2.5	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.5	4.9	GO:0030884	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.5	1.5	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.5	1.5	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.5	1.9	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5	1.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.5	2.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.5	1.8	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5	1.8	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.5	2.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.5	1.8	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.5	4.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4	7.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.4	3.6	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.4	1.8	GO:0001855	complement component C4b binding(GO:0001855)
0.4	2.6	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.4	13.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.4	32.5	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.4	1.7	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.4	6.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.4	3.2	GO:0004111	creatine kinase activity(GO:0004111)
0.4	1.2	GO:0005174	CD40 receptor binding(GO:0005174)
0.4	68.8	GO:0003823	antigen binding(GO:0003823)
0.4	4.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4	1.1	GO:0005549	odorant binding(GO:0005549)
0.4	1.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4	2.1	GO:0003796	lysozyme activity(GO:0003796)
0.4	3.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	1.7	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.3	3.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.3	4.7	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3	2.7	GO:0004565	beta-galactosidase activity(GO:0004565)
0.3	4.7	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.3	3.3	GO:0031433	telethonin binding(GO:0031433)
0.3	2.3	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.3	39.9	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.3	1.3	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.3	2.0	GO:0050692	DBD domain binding(GO:0050692)
0.3	2.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.3	3.7	GO:0032027	myosin light chain binding(GO:0032027)
0.3	4.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.3	3.0	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3	1.2	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3	1.8	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.3	2.7	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3	3.0	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.3	5.0	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.3	3.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3	1.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.3	5.3	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.3	0.8	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.3	8.4	GO:0005123	death receptor binding(GO:0005123)
0.3	2.7	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	6.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	2.9	GO:0019957	C-C chemokine binding(GO:0019957)
0.3	1.0	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3	0.8	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2	25.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	3.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	3.4	GO:0031402	sodium ion binding(GO:0031402)
0.2	0.7	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.2	2.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.2	0.9	GO:0055102	lipase inhibitor activity(GO:0055102)
0.2	3.9	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	2.5	GO:0008430	selenium binding(GO:0008430)
0.2	4.1	GO:0070330	aromatase activity(GO:0070330)
0.2	36.9	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2	1.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.2	1.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.2	2.2	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2	1.0	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2	1.9	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.2	5.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	1.0	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2	5.9	GO:0005212	structural constituent of eye lens(GO:0005212)
0.2	3.8	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.2	2.5	GO:0005344	oxygen transporter activity(GO:0005344)
0.2	2.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2	1.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.2	1.7	GO:0004707	MAP kinase activity(GO:0004707)
0.2	2.8	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.2	6.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	0.5	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2	1.0	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.2	1.6	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	1.6	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2	1.1	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.2	2.6	GO:0005537	mannose binding(GO:0005537)
0.2	16.2	GO:0004896	cytokine receptor activity(GO:0004896)
0.2	0.8	GO:0017018	myosin phosphatase activity(GO:0017018)
0.2	6.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	1.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	3.5	GO:0070403	NAD+ binding(GO:0070403)
0.1	1.0	GO:0097643	amylin receptor activity(GO:0097643)
0.1	0.4	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	1.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	1.9	GO:0036122	BMP binding(GO:0036122)
0.1	6.8	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	11.0	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.1	3.0	GO:0008201	heparin binding(GO:0008201)
0.1	1.9	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	3.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	4.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.8	GO:0004447	iodide peroxidase activity(GO:0004447)
0.1	2.0	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	4.8	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	4.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	1.9	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	2.7	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	5.5	GO:0050699	WW domain binding(GO:0050699)
0.1	2.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	1.0	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	2.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	6.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	1.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.8	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.9	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	1.3	GO:0045159	myosin II binding(GO:0045159)
0.1	1.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	18.5	GO:0017124	SH3 domain binding(GO:0017124)
0.1	2.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	3.3	GO:0004623	phospholipase A2 activity(GO:0004623)
0.1	4.9	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	0.5	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	1.4	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	1.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	2.7	GO:0031489	myosin V binding(GO:0031489)
0.1	6.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1	4.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.1	4.4	GO:0043621	protein self-association(GO:0043621)
0.1	17.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	3.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.7	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	2.3	GO:0042287	MHC protein binding(GO:0042287)
0.1	4.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	0.7	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	7.8	GO:0005262	calcium channel activity(GO:0005262)
0.1	0.5	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	1.7	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	29.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1	0.2	GO:0036033	mediator complex binding(GO:0036033)
0.1	0.5	GO:0008242	omega peptidase activity(GO:0008242)
0.1	10.8	GO:0005178	integrin binding(GO:0005178)
0.1	5.9	GO:0019903	protein phosphatase binding(GO:0019903)
0.1	0.6	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.1	0.6	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.8	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	1.2	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.6	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	2.5	GO:0097110	scaffold protein binding(GO:0097110)
0.1	1.0	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	1.1	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.3	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	2.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	3.9	GO:0016782	transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1	1.1	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.0	0.6	GO:0004386	helicase activity(GO:0004386)
0.0	0.6	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.4	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	1.0	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	2.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	2.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	2.5	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	1.5	GO:0008083	growth factor activity(GO:0008083)
0.0	0.7	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.3	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	30.5	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	1.6	GO:0043022	ribosome binding(GO:0043022)
0.0	0.8	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.9	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	2.3	GO:0005179	hormone activity(GO:0005179)
0.0	0.4	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	1.7	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	1.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	1.1	GO:0030332	cyclin binding(GO:0030332)
0.0	1.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	1.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.9	GO:0001664	G-protein coupled receptor binding(GO:0001664)
0.0	0.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.7	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095) protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	26.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.8	25.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.7	21.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7	17.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.7	9.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.7	73.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	31.7	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.6	3.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6	31.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.5	27.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.5	3.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.5	22.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.4	23.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.4	16.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.4	9.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	6.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	11.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.2	3.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	5.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	3.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	9.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	10.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	15.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	4.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	9.2	PID CDC42 PATHWAY	CDC42 signaling events
0.2	2.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	4.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	9.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	3.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	6.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	6.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	3.7	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	4.4	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	3.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	2.8	PID RHOA PATHWAY	RhoA signaling pathway
0.1	4.3	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	2.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	1.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	1.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	3.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.4	ST ADRENERGIC	Adrenergic Pathway
0.1	2.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	1.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	17.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	2.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	11.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.1	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	2.0	PID ATR PATHWAY	ATR signaling pathway
0.1	0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	15.2	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	2.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.7	PID ATM PATHWAY	ATM pathway
0.0	5.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.6	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	44.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
1.6	15.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.5	7.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
1.3	34.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
1.1	19.3	REACTOME DEFENSINS	Genes involved in Defensins
1.1	50.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.9	75.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8	8.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.7	17.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.7	2.9	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.7	30.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.7	1.4	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.6	9.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.6	31.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.5	9.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.5	15.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.5	18.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.5	5.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	6.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.4	6.5	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.4	7.8	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.4	9.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.4	12.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	32.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3	13.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	2.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.7	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.3	1.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3	12.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	43.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.3	3.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	9.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.2	5.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	17.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	6.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	2.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	4.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	12.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	9.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	5.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	3.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2	4.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	5.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	5.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	7.6	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.2	2.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.2	2.8	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	3.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	1.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	3.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	6.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	5.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	2.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	4.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	3.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	6.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	1.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.9	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.1	2.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	5.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	4.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	0.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	4.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	1.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	25.4	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	2.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	3.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	2.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.6	REACTOME OPSINS	Genes involved in Opsins
0.1	1.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	0.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	7.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	1.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	1.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.0	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides