Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for TAF1
Z-value: 1.07
Motif logo
Transcription factors associated with TAF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TAF1 | hg19_v2_chrX_+_70586082_70586114 | -0.52 | 2.9e-16 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TAF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.9 | 939.0 | GO:0070125 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 9.0 | 582.9 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 3.4 | 507.3 | GO:0045047 | protein targeting to ER(GO:0045047) |
| 2.2 | 454.4 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 11.2 | 347.3 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 3.7 | 265.1 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 15.3 | 259.7 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 2.1 | 258.6 | GO:0008380 | RNA splicing(GO:0008380) |
| 5.0 | 231.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 4.2 | 227.6 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.0 | 541.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 8.5 | 521.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 4.0 | 431.0 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 2.4 | 356.7 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.8 | 318.7 | GO:0005635 | nuclear envelope(GO:0005635) |
| 3.0 | 304.6 | GO:0005840 | ribosome(GO:0005840) |
| 37.8 | 302.1 | GO:0042382 | paraspeckles(GO:0042382) |
| 15.7 | 283.1 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 10.8 | 270.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 6.5 | 267.3 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 2160.4 | GO:0003723 | RNA binding(GO:0003723) |
| 4.9 | 1068.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 10.5 | 555.1 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 6.0 | 381.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 11.0 | 296.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 4.1 | 289.4 | GO:0019003 | GDP binding(GO:0019003) |
| 6.3 | 269.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 8.8 | 265.1 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 5.4 | 248.6 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 6.6 | 231.6 | GO:0051059 | NF-kappaB binding(GO:0051059) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.5 | 443.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 3.0 | 291.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 5.0 | 287.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 2.3 | 268.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 5.2 | 235.3 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 2.1 | 205.1 | PID CDC42 PATHWAY | CDC42 signaling events |
| 4.6 | 187.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 1.7 | 165.8 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 4.0 | 158.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.9 | 122.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.8 | 1123.5 | REACTOME TRANSLATION | Genes involved in Translation |
| 10.1 | 857.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 6.1 | 680.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 8.1 | 634.3 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 8.5 | 381.0 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 9.9 | 357.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 7.8 | 305.0 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 1.8 | 275.8 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 8.6 | 267.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 11.3 | 258.8 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |