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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for TBX1

Z-value: 0.81

Motif logo

Transcription factors associated with TBX1

Gene Symbol Gene ID Gene Info
ENSG00000184058.8 T-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX1hg19_v2_chr22_+_19744226_197442260.363.3e-08Click!

Activity profile of TBX1 motif

Sorted Z-values of TBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_37407212 28.40 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
zinc finger protein 568
chr19_+_56915668 27.71 ENST00000333201.9
ENST00000391778.3
zinc finger protein 583
chr22_-_27620603 23.00 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1
chr19_-_9731872 22.46 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
zinc finger protein 561
chr1_+_89829610 20.14 ENST00000370456.4
ENST00000535065.1
guanylate binding protein family, member 6
chr4_-_120133661 19.51 ENST00000503243.1
ENST00000326780.3
Uncharacterized protein
chr3_-_57678772 18.94 ENST00000311128.5
DENN/MADD domain containing 6A
chr18_+_21693306 18.30 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr11_-_64511789 17.25 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_115630900 17.16 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
long intergenic non-protein coding RNA 900
chr13_+_114567131 17.01 ENST00000608651.1
GAS6 antisense RNA 2 (head to head)
chr16_+_31271274 16.09 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr17_-_5138099 15.59 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SLP adaptor and CSK interacting membrane protein
chr15_-_42076229 15.17 ENST00000597767.1
Uncharacterized protein
chr19_+_45973120 14.91 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_76155618 14.40 ENST00000530759.1
RP11-111M22.3
chr20_+_30640004 14.39 ENST00000520553.1
ENST00000518730.1
ENST00000375852.2
hemopoietic cell kinase
chr14_+_75746781 14.31 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_15911510 13.58 ENST00000375826.3
agmatine ureohydrolase (agmatinase)
chr12_-_53594227 13.57 ENST00000550743.2
integrin, beta 7
chr11_-_76155700 13.27 ENST00000572035.1
RP11-111M22.3
chr22_-_17702729 13.11 ENST00000449907.2
ENST00000441548.1
ENST00000399839.1
cat eye syndrome chromosome region, candidate 1
chr19_-_51875894 12.93 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr21_-_46340884 12.70 ENST00000302347.5
ENST00000517819.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_84937314 12.60 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr4_+_128554081 12.43 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr12_-_10022735 12.29 ENST00000228438.2
C-type lectin domain family 2, member B
chr18_+_74240610 11.72 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr21_-_46340770 11.67 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_+_1993173 11.32 ENST00000523438.1
myomesin 2
chr6_-_74161977 11.11 ENST00000370318.1
ENST00000370315.3
Mab-21 domain containing 1
chr1_+_28199047 11.05 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
thymocyte selection associated family member 2
chr18_+_71815743 10.92 ENST00000169551.6
ENST00000580087.1
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr7_+_99816859 10.85 ENST00000317271.2
poliovirus receptor related immunoglobulin domain containing
chr12_+_32112340 10.81 ENST00000540924.1
ENST00000312561.4
KIAA1551
chr5_-_131132614 10.55 ENST00000307968.7
ENST00000307954.8
folliculin interacting protein 1
chr12_-_8025499 10.36 ENST00000431042.2
solute carrier family 2 (facilitated glucose transporter), member 14
chrX_-_103401649 10.13 ENST00000357421.4
solute carrier family 25, member 53
chr16_+_53468332 10.09 ENST00000262133.6
retinoblastoma-like 2 (p130)
chr5_-_137514617 10.06 ENST00000254900.5
bromodomain containing 8
chr2_+_90248739 9.75 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr8_+_12809093 9.73 ENST00000528753.2
KIAA1456
chr2_-_89310012 9.51 ENST00000493819.1
immunoglobulin kappa variable 1-9
chrX_+_128913906 9.51 ENST00000356892.3
SAM and SH3 domain containing 3
chr14_-_106054659 9.48 ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr12_-_8025623 9.36 ENST00000542782.1
ENST00000396589.2
ENST00000535266.1
ENST00000542505.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr12_-_54691668 9.34 ENST00000553198.1
nuclear factor, erythroid 2
chr1_+_111773349 9.30 ENST00000533831.2
chitinase 3-like 2
chr19_-_39826639 9.25 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
glia maturation factor, gamma
chr16_-_30546141 9.12 ENST00000535210.1
ENST00000395094.3
zinc finger protein 747
chr1_-_15735925 9.08 ENST00000427824.1
RP3-467K16.4
chr14_-_106174960 8.86 ENST00000390547.2
immunoglobulin heavy constant alpha 1
chr16_+_2587998 8.80 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr12_-_15104040 8.80 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr16_-_46865047 8.80 ENST00000394806.2
chromosome 16 open reading frame 87
chr9_+_10613163 8.79 ENST00000429581.2
RP11-87N24.2
chr2_-_196933536 8.76 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chr3_-_196065248 8.56 ENST00000446879.1
ENST00000273695.3
transmembrane 4 L six family member 19
chr9_-_110251836 8.54 ENST00000374672.4
Kruppel-like factor 4 (gut)
chr16_+_2587965 8.54 ENST00000342085.4
ENST00000566659.1
3-phosphoinositide dependent protein kinase-1
chr19_+_47759716 8.50 ENST00000221922.6
coiled-coil domain containing 9
chr1_+_244998602 8.47 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chr19_-_13213662 8.45 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr19_+_1065922 8.38 ENST00000539243.2
histocompatibility (minor) HA-1
chr19_+_544034 8.32 ENST00000592501.1
ENST00000264553.3
granzyme M (lymphocyte met-ase 1)
chr6_-_27858570 8.20 ENST00000359303.2
histone cluster 1, H3j
chr19_+_859425 8.19 ENST00000327726.6
complement factor D (adipsin)
chr3_-_127317047 8.17 ENST00000462228.1
ENST00000490643.1
transmembrane protein, adipocyte asscociated 1
chr9_+_17134980 8.17 ENST00000380647.3
centlein, centrosomal protein
chr5_+_81575281 8.15 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr2_-_208489707 8.15 ENST00000448007.2
ENST00000432416.1
ENST00000411432.1
methyltransferase like 21A
chr12_-_91539918 8.14 ENST00000548218.1
decorin
chr17_-_42452063 8.08 ENST00000588098.1
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr3_+_40547483 7.99 ENST00000420891.1
ENST00000314529.6
ENST00000418905.1
zinc finger protein 620
chr1_-_27952741 7.96 ENST00000399173.1
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr7_-_36764004 7.95 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr1_-_11866034 7.94 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr7_-_36764142 7.93 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr1_+_16090914 7.92 ENST00000441801.2
filamin binding LIM protein 1
chr8_-_8318847 7.90 ENST00000521218.1
CTA-398F10.2
chr5_+_54320078 7.90 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr5_-_131132658 7.88 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr6_-_2842219 7.88 ENST00000380739.5
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_217724767 7.87 ENST00000236979.2
transition protein 1 (during histone to protamine replacement)
chr1_+_38022572 7.87 ENST00000541606.1
dynein, axonemal, light intermediate chain 1
chr1_+_11866270 7.86 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr6_-_32160622 7.84 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr17_-_76836729 7.82 ENST00000587783.1
ENST00000542802.3
ENST00000586531.1
ENST00000589424.1
ENST00000590546.2
ubiquitin specific peptidase 36
chr2_+_103089756 7.81 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr16_-_4466622 7.71 ENST00000570645.1
ENST00000574025.1
ENST00000572898.1
ENST00000537233.2
ENST00000571059.1
ENST00000251166.4
coronin 7
chr17_-_15244894 7.70 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr20_+_30639991 7.68 ENST00000534862.1
ENST00000538448.1
ENST00000375862.2
hemopoietic cell kinase
chr19_-_55866061 7.56 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr11_+_28129795 7.54 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
methyltransferase like 15
chr1_+_209929377 7.53 ENST00000400959.3
ENST00000367025.3
TRAF3 interacting protein 3
chr1_-_169680745 7.52 ENST00000236147.4
selectin L
chr4_-_681114 7.50 ENST00000503156.1
major facilitator superfamily domain containing 7
chr12_+_54892550 7.41 ENST00000545638.2
NCK-associated protein 1-like
chr4_+_113066552 7.39 ENST00000309733.5
chromosome 4 open reading frame 32
chr19_-_21950362 7.38 ENST00000358296.6
zinc finger protein 100
chr6_+_131894284 7.33 ENST00000368087.3
ENST00000356962.2
arginase 1
chr12_+_69742121 7.28 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
lysozyme
chrX_-_70329118 7.27 ENST00000374188.3
interleukin 2 receptor, gamma
chr17_+_80416050 7.26 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr17_-_29641084 7.25 ENST00000544462.1
ecotropic viral integration site 2B
chr10_-_21661870 7.25 ENST00000433460.1
RP11-275N1.1
chr8_+_1993152 7.24 ENST00000262113.4
myomesin 2
chr7_-_99149715 7.23 ENST00000449309.1
family with sequence similarity 200, member A
chr16_+_2588012 7.22 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr5_+_148786423 7.08 ENST00000505254.2
ENST00000602964.1
ENST00000519898.1
MIR143 host gene (non-protein coding)
chr19_-_36822595 7.04 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
long intergenic non-protein coding RNA 665
chrX_-_48433275 7.03 ENST00000376775.2
Uncharacterized protein; cDNA FLJ26048 fis, clone PRS02384
chr2_+_61108771 7.01 ENST00000394479.3
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_-_61880248 6.95 ENST00000525556.1
AC022182.3
chr9_-_116102562 6.91 ENST00000374193.4
ENST00000465979.1
WD repeat domain 31
chr1_+_38022513 6.90 ENST00000296218.7
dynein, axonemal, light intermediate chain 1
chr19_-_14016877 6.90 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
chromosome 19 open reading frame 57
chrX_+_37639264 6.87 ENST00000378588.4
cytochrome b-245, beta polypeptide
chr4_-_156875003 6.84 ENST00000433477.3
cathepsin O
chr19_-_39390350 6.82 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr4_+_154622652 6.77 ENST00000260010.6
toll-like receptor 2
chr12_+_54891495 6.72 ENST00000293373.6
NCK-associated protein 1-like
chr17_+_27055798 6.72 ENST00000268766.6
NIMA-related kinase 8
chr19_-_54327542 6.71 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
NLR family, pyrin domain containing 12
chr1_+_16062820 6.71 ENST00000294454.5
solute carrier family 25, member 34
chr18_+_74240756 6.58 ENST00000584910.1
ENST00000582452.1
long intergenic non-protein coding RNA 908
chr11_+_1940786 6.57 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
troponin T type 3 (skeletal, fast)
chr22_+_22786288 6.56 ENST00000390301.2
immunoglobulin lambda variable 1-36
chr9_+_17135016 6.52 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr14_-_23288930 6.51 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_-_55866997 6.47 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chrX_+_49216659 6.46 ENST00000415752.1
G antigen 12I
chr2_-_96811170 6.45 ENST00000288943.4
dual specificity phosphatase 2
chr3_+_10068095 6.43 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
Fanconi anemia, complementation group D2
chr5_+_34929677 6.42 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DnaJ (Hsp40) homolog, subfamily C, member 21
chrX_+_37639302 6.41 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr5_-_130970723 6.40 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
Rap guanine nucleotide exchange factor (GEF) 6
chr7_+_72742178 6.40 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr8_+_103563792 6.29 ENST00000285402.3
outer dense fiber of sperm tails 1
chr17_+_80416482 6.28 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr1_+_209929494 6.26 ENST00000367026.3
TRAF3 interacting protein 3
chr3_+_187871060 6.24 ENST00000448637.1
LIM domain containing preferred translocation partner in lipoma
chr5_+_80597419 6.23 ENST00000254037.2
ENST00000407610.3
ENST00000380199.5
zinc finger, CCHC domain containing 9
chr19_-_50529193 6.21 ENST00000596445.1
ENST00000599538.1
vaccinia related kinase 3
chrY_+_15016725 6.20 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_-_11865982 6.13 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr3_+_32726774 6.10 ENST00000538368.1
CCR4-NOT transcription complex, subunit 10
chr12_-_123849374 6.09 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr16_+_640201 6.07 ENST00000563109.1
RAB40C, member RAS oncogene family
chr7_-_142176790 6.06 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr17_-_8021710 6.06 ENST00000380149.1
ENST00000448843.2
arachidonate lipoxygenase 3
chr7_+_150264365 6.06 ENST00000255945.2
ENST00000461940.1
GTPase, IMAP family member 4
chr16_-_33647696 6.06 ENST00000558425.1
ENST00000569103.2
Uncharacterized protein
chr8_-_66474884 6.05 ENST00000520902.1
CTD-3025N20.2
chr7_-_71801980 6.05 ENST00000329008.5
calneuron 1
chr16_+_33020496 6.03 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr2_+_61108650 6.02 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr11_-_33913708 5.99 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr7_+_143013198 5.95 ENST00000343257.2
chloride channel, voltage-sensitive 1
chr14_-_90798418 5.94 ENST00000354366.3
NRDE-2, necessary for RNA interference, domain containing
chr2_-_25475120 5.88 ENST00000380746.4
ENST00000402667.1
DNA (cytosine-5-)-methyltransferase 3 alpha
chr7_+_5919458 5.85 ENST00000416608.1
oncomodulin
chr11_-_236326 5.82 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
sirtuin 3
chr1_-_36948879 5.81 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
colony stimulating factor 3 receptor (granulocyte)
chr2_+_219247021 5.81 ENST00000539932.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr19_-_18366182 5.81 ENST00000355502.3
phosphodiesterase 4C, cAMP-specific
chr2_-_192016316 5.80 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
signal transducer and activator of transcription 4
chr6_+_31582961 5.79 ENST00000376059.3
ENST00000337917.7
allograft inflammatory factor 1
chr19_+_859654 5.74 ENST00000592860.1
complement factor D (adipsin)
chr6_-_159421198 5.71 ENST00000252655.1
ENST00000297262.3
ENST00000367069.2
radial spoke 3 homolog (Chlamydomonas)
chrX_-_153191674 5.70 ENST00000350060.5
ENST00000370016.1
Rho GTPase activating protein 4
chr10_-_76868931 5.66 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
dual specificity phosphatase 13
chr14_-_106963409 5.66 ENST00000390621.2
immunoglobulin heavy variable 1-45
chr3_-_49459865 5.65 ENST00000427987.1
aminomethyltransferase
chr10_-_13523073 5.59 ENST00000440282.1
BEN domain containing 7
chr15_+_93749295 5.57 ENST00000599897.1
AC112693.2
chrX_+_56259316 5.55 ENST00000468660.1
Kruppel-like factor 8
chr7_+_139478030 5.53 ENST00000425687.1
ENST00000263552.6
ENST00000438104.1
ENST00000336425.5
thromboxane A synthase 1 (platelet)
chr1_-_67390474 5.53 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WD repeat domain 78
chrX_+_123480194 5.52 ENST00000371139.4
SH2 domain containing 1A
chr22_+_32149927 5.51 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEP domain containing 5
chr15_-_78423763 5.50 ENST00000557846.1
calcium and integrin binding family member 2
chr20_-_524362 5.49 ENST00000460062.2
ENST00000608066.1
casein kinase 2, alpha 1 polypeptide
chr20_+_4702548 5.47 ENST00000305817.2
prion protein 2 (dublet)
chr19_-_4535233 5.47 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr17_-_40333099 5.44 ENST00000607371.1
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_92417716 5.42 ENST00000402388.1
bromodomain, testis-specific
chr2_+_68592305 5.41 ENST00000234313.7
pleckstrin
chr11_+_71846764 5.32 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
folate receptor 3 (gamma)
chr11_-_133826852 5.30 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr17_-_29641104 5.28 ENST00000577894.1
ENST00000330927.4
ecotropic viral integration site 2B
chr12_-_8025398 5.26 ENST00000535344.1
ENST00000543909.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr3_-_146213722 5.25 ENST00000336685.2
ENST00000489015.1
phospholipid scramblase 2
chr1_-_36947120 5.25 ENST00000361632.4
colony stimulating factor 3 receptor (granulocyte)
chr5_-_176433350 5.23 ENST00000377227.4
ENST00000377219.2
ubiquitin interaction motif containing 1
chr4_+_15704573 5.23 ENST00000265016.4
bone marrow stromal cell antigen 1
chr12_-_8025442 5.22 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
solute carrier family 2 (facilitated glucose transporter), member 14
chr2_-_97304105 5.21 ENST00000599854.1
ENST00000441706.2
KAT8 regulatory NSL complex subunit 3
chr14_-_25103472 5.19 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_+_55014013 5.19 ENST00000301202.2
leukocyte-associated immunoglobulin-like receptor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
4.6 18.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
4.1 20.3 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
3.6 18.2 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
3.4 13.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.4 13.5 GO:0032661 regulation of interleukin-18 production(GO:0032661)
3.3 13.2 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
3.1 15.3 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
2.9 14.3 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
2.8 14.2 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
2.8 8.3 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
2.7 10.7 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
2.6 7.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
2.5 7.6 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
2.3 18.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
2.2 6.6 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
2.2 8.8 GO:0071461 cellular response to redox state(GO:0071461)
2.2 21.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
2.1 10.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.0 16.2 GO:0001661 conditioned taste aversion(GO:0001661)
2.0 20.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.0 6.1 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
2.0 5.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.9 13.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.9 5.6 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.8 12.8 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
1.8 5.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.8 5.4 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
1.8 5.4 GO:0097254 renal tubular secretion(GO:0097254)
1.8 5.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.7 19.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.7 6.8 GO:0010587 miRNA catabolic process(GO:0010587)
1.7 8.6 GO:0050893 sensory processing(GO:0050893)
1.7 5.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
1.7 8.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.7 8.3 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
1.7 5.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
1.7 5.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
1.6 4.9 GO:0043366 beta selection(GO:0043366)
1.6 4.9 GO:0048859 formation of anatomical boundary(GO:0048859)
1.6 4.9 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
1.6 3.2 GO:0021938 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
1.6 4.9 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.6 1.6 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
1.6 4.7 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
1.6 4.7 GO:2000870 regulation of progesterone secretion(GO:2000870)
1.5 1.5 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.5 4.5 GO:2000308 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) positive regulation of bone mineralization involved in bone maturation(GO:1900159) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
1.5 4.5 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.5 19.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
1.5 8.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.5 7.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.5 4.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
1.5 8.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.5 1.5 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.5 7.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.5 43.6 GO:0097242 beta-amyloid clearance(GO:0097242)
1.5 10.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
1.4 11.1 GO:0034587 piRNA metabolic process(GO:0034587)
1.4 4.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.4 2.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
1.3 4.0 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
1.3 5.2 GO:0017121 phospholipid scrambling(GO:0017121)
1.3 3.9 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.3 16.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
1.3 3.8 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.2 5.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.2 1.2 GO:0046602 mitotic centrosome separation(GO:0007100) regulation of mitotic centrosome separation(GO:0046602) centrosome separation(GO:0051299)
1.2 6.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
1.2 6.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
1.2 3.6 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.2 7.2 GO:0070560 protein secretion by platelet(GO:0070560)
1.2 1.2 GO:0014806 smooth muscle hyperplasia(GO:0014806)
1.2 3.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
1.2 3.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.1 9.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.1 5.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.1 11.2 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
1.1 6.6 GO:0032466 negative regulation of cytokinesis(GO:0032466)
1.1 9.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
1.1 5.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
1.1 4.3 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
1.1 6.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.1 4.3 GO:0045588 allantoin metabolic process(GO:0000255) positive regulation of gamma-delta T cell differentiation(GO:0045588)
1.1 5.3 GO:0061107 seminal vesicle development(GO:0061107)
1.1 29.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
1.0 8.4 GO:0070475 rRNA base methylation(GO:0070475)
1.0 4.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.0 11.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.0 7.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.0 24.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
1.0 4.1 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
1.0 5.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.0 6.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.0 10.1 GO:0001955 blood vessel maturation(GO:0001955)
1.0 3.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.0 4.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.0 11.7 GO:0031167 rRNA methylation(GO:0031167)
1.0 2.9 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
1.0 1.9 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.0 2.9 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.0 2.9 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.9 3.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.9 16.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.9 3.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.9 2.8 GO:0019858 cytosine metabolic process(GO:0019858)
0.9 3.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.9 7.2 GO:1902302 regulation of potassium ion export(GO:1902302) regulation of potassium ion export across plasma membrane(GO:1903764)
0.9 4.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.9 10.8 GO:0015884 folic acid transport(GO:0015884)
0.9 2.7 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.9 2.7 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.9 13.3 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.9 5.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.9 2.6 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.9 2.6 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.9 2.6 GO:0008078 mesoderm migration involved in gastrulation(GO:0007509) mesodermal cell migration(GO:0008078)
0.9 1.7 GO:0051693 actin filament capping(GO:0051693)
0.9 7.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.8 2.5 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.8 3.4 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.8 14.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.8 1.6 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.8 4.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.8 0.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.8 2.4 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.8 3.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 2.3 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.8 16.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 2.3 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.8 1.5 GO:0032762 mast cell cytokine production(GO:0032762)
0.8 2.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.8 4.6 GO:0048241 epinephrine transport(GO:0048241)
0.8 3.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 4.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.8 5.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.8 2.3 GO:0045082 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.8 3.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.8 6.8 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.8 0.8 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.8 6.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.7 3.7 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.7 5.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.7 7.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.7 4.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.7 2.2 GO:0033504 floor plate development(GO:0033504)
0.7 2.9 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.7 3.6 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.7 13.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 15.8 GO:0097186 amelogenesis(GO:0097186)
0.7 2.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.7 1.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.7 3.5 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.7 4.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.7 5.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.7 4.8 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.7 0.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.7 12.2 GO:0071318 cellular response to ATP(GO:0071318)
0.7 9.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.7 4.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.7 2.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.7 4.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.7 2.7 GO:0090527 actin filament reorganization(GO:0090527)
0.7 2.6 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.7 7.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.6 2.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.6 8.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.6 5.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 1.9 GO:0042701 progesterone secretion(GO:0042701)
0.6 1.9 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.6 7.6 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.6 9.4 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6 3.8 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.6 4.4 GO:1903232 melanosome assembly(GO:1903232)
0.6 3.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.6 3.7 GO:0015747 urate transport(GO:0015747)
0.6 4.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.6 14.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.6 1.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.6 2.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.6 13.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 2.4 GO:0006710 androgen catabolic process(GO:0006710)
0.6 3.0 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6 2.4 GO:1904327 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.6 10.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 1.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.6 8.2 GO:0040016 embryonic cleavage(GO:0040016)
0.6 2.3 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.6 9.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 4.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.6 4.0 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.6 2.8 GO:0046968 peptide antigen transport(GO:0046968)
0.6 38.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.6 2.8 GO:0044336 embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.6 1.7 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.6 5.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.6 1.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 7.2 GO:0044144 growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.5 1.6 GO:1903463 vacuolar phosphate transport(GO:0007037) regulation of mitotic cell cycle DNA replication(GO:1903463) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.5 2.7 GO:0015692 lead ion transport(GO:0015692)
0.5 1.6 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.5 6.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.5 2.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.5 1.1 GO:0035962 response to interleukin-13(GO:0035962)
0.5 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.5 0.5 GO:0045399 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.5 3.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.5 1.1 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.5 2.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.5 1.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.5 1.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 7.4 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.5 4.2 GO:0016236 macroautophagy(GO:0016236)
0.5 2.1 GO:0007525 somatic muscle development(GO:0007525)
0.5 1.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5 3.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.5 2.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.5 10.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.5 1.5 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.5 3.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 3.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.5 1.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.5 3.5 GO:0006265 DNA topological change(GO:0006265)
0.5 2.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.5 1.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.5 0.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.5 4.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.5 1.5 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.5 1.0 GO:0045911 positive regulation of DNA recombination(GO:0045911)
0.5 2.4 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.5 5.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.5 1.4 GO:0045925 female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.5 1.9 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.5 2.8 GO:0007341 penetration of zona pellucida(GO:0007341)
0.5 6.6 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.5 3.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.5 2.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.5 0.9 GO:0046113 nucleobase catabolic process(GO:0046113)
0.5 2.3 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5 20.0 GO:0032570 response to progesterone(GO:0032570)
0.5 2.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.5 1.4 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.4 6.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.4 2.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 2.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 1.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 1.3 GO:0046219 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.4 1.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.4 10.4 GO:0033198 response to ATP(GO:0033198)
0.4 3.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 3.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.4 2.0 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 1.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.6 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.4 1.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.4 1.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.4 5.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 0.8 GO:0043132 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.4 7.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 1.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 1.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.4 1.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.4 7.0 GO:0071420 cellular response to histamine(GO:0071420)
0.4 1.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 4.2 GO:0001778 plasma membrane repair(GO:0001778)
0.4 2.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 8.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 4.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.4 2.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 3.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.4 2.3 GO:0018343 protein farnesylation(GO:0018343)
0.4 9.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.4 3.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.4 4.8 GO:1903358 regulation of Golgi organization(GO:1903358)
0.4 0.7 GO:0090009 primitive streak formation(GO:0090009)
0.4 2.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4 1.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.4 5.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 1.1 GO:0035054 septum secundum development(GO:0003285) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.4 2.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.4 1.1 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 4.0 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.4 7.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 2.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.4 1.8 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.4 2.8 GO:0016180 snRNA processing(GO:0016180)
0.4 1.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.4 3.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 3.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.3 2.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.3 1.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.3 5.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.3 6.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.3 28.7 GO:0050776 regulation of immune response(GO:0050776)
0.3 1.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 2.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.3 5.7 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 1.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.3 8.0 GO:0003341 cilium movement(GO:0003341)
0.3 3.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 1.0 GO:0042938 dipeptide transport(GO:0042938)
0.3 8.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 4.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 12.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.3 1.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.9 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.3 7.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 2.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 20.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.3 1.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.3 1.2 GO:0032571 response to vitamin K(GO:0032571)
0.3 0.6 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.3 10.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 5.5 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.3 0.9 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 3.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 9.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.3 3.3 GO:0030033 microvillus assembly(GO:0030033)
0.3 1.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 3.6 GO:0015871 choline transport(GO:0015871)
0.3 3.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 3.8 GO:0051382 kinetochore assembly(GO:0051382)
0.3 2.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 1.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.3 0.9 GO:0048850 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.3 1.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.3 4.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.3 2.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509) membrane protein proteolysis(GO:0033619)
0.3 0.8 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.3 1.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 2.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 8.3 GO:0019835 cytolysis(GO:0019835)
0.3 4.7 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.3 0.8 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.3 5.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.3 3.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 5.2 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.3 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 1.3 GO:0035617 stress granule disassembly(GO:0035617)
0.3 5.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 2.4 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 1.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.3 0.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3 1.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 1.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.3 2.7 GO:0046514 ceramide catabolic process(GO:0046514)
0.3 1.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.3 3.7 GO:0010002 cardioblast differentiation(GO:0010002)
0.3 8.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 5.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 0.8 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 1.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 8.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 9.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.3 2.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.3 10.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 2.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 2.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 7.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 2.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 2.2 GO:0009642 response to light intensity(GO:0009642)
0.2 1.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 8.5 GO:0030317 sperm motility(GO:0030317)
0.2 4.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 1.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 4.7 GO:0048485 sympathetic nervous system development(GO:0048485)
0.2 1.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 5.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 2.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 2.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 3.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 0.7 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 1.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 0.9 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.2 1.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 11.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 3.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 1.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.0 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.2 1.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 1.7 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.2 1.4 GO:0015705 iodide transport(GO:0015705)
0.2 3.5 GO:0030449 regulation of complement activation(GO:0030449)
0.2 2.7 GO:0036010 protein localization to endosome(GO:0036010)
0.2 5.9 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 2.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 5.5 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.2 6.1 GO:0097484 dendrite extension(GO:0097484)
0.2 1.8 GO:0070673 response to interleukin-18(GO:0070673)
0.2 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.8 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.2 1.8 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2 14.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.4 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.2 2.8 GO:0035082 axoneme assembly(GO:0035082)
0.2 2.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.7 GO:0030279 negative regulation of ossification(GO:0030279)
0.2 0.4 GO:0046684 response to pyrethroid(GO:0046684)
0.2 5.0 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.2 11.4 GO:0006968 cellular defense response(GO:0006968)
0.2 1.3 GO:0060326 cell chemotaxis(GO:0060326)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 3.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 1.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 13.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 3.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.7 GO:1901159 xylulose metabolic process(GO:0005997) glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.2 1.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 3.0 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 3.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2 21.1 GO:0002377 immunoglobulin production(GO:0002377)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 3.4 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.2 1.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.2 3.4 GO:0045026 plasma membrane fusion(GO:0045026)
0.2 1.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 5.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 7.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.2 0.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 0.5 GO:0019417 sulfur oxidation(GO:0019417)
0.2 1.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 2.9 GO:0007618 mating(GO:0007618)
0.2 2.7 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.2 4.8 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.2 14.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 16.8 GO:0042742 defense response to bacterium(GO:0042742)
0.2 6.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 0.3 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.2 0.3 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.2 5.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.2 0.9 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.2 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 1.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 3.1 GO:0048536 spleen development(GO:0048536)
0.2 0.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 3.0 GO:0044804 nucleophagy(GO:0044804)
0.1 1.2 GO:0016246 RNA interference(GO:0016246)
0.1 1.0 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 10.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 2.8 GO:0051028 mRNA transport(GO:0051028)
0.1 3.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 3.2 GO:0033344 cholesterol efflux(GO:0033344)
0.1 1.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 5.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.1 0.7 GO:0031329 regulation of cellular catabolic process(GO:0031329)
0.1 1.5 GO:0070482 response to oxygen levels(GO:0070482)
0.1 2.2 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 1.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.4 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 1.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.0 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.8 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:0045779 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 2.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.9 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 3.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.7 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 2.8 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.1 1.4 GO:0072348 sulfur compound transport(GO:0072348)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 3.5 GO:0006959 humoral immune response(GO:0006959)
0.1 1.1 GO:0008033 tRNA processing(GO:0008033)
0.1 3.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.1 GO:0000732 strand displacement(GO:0000732)
0.1 1.0 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.0 GO:0060348 bone development(GO:0060348)
0.1 0.9 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.7 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 2.0 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.5 GO:0036101 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 4.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 1.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 1.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.3 GO:0021549 cerebellum development(GO:0021549) metencephalon development(GO:0022037)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1 1.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 3.3 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.1 1.3 GO:0071320 cellular response to cAMP(GO:0071320)
0.1 0.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 2.8 GO:0021510 spinal cord development(GO:0021510)
0.1 1.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.1 1.5 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 1.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 14.2 GO:0002250 adaptive immune response(GO:0002250)
0.1 0.7 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 2.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.1 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.2 GO:0051647 nucleus localization(GO:0051647)
0.1 4.6 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.1 0.3 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 4.6 GO:0007286 spermatid development(GO:0007286)
0.1 0.8 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 1.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 3.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.3 GO:1904754 positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1 0.3 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.1 2.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.0 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 0.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.2 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.5 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.1 0.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.8 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.6 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.5 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.1 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.2 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.0 GO:0001945 lymph vessel development(GO:0001945)
0.0 1.8 GO:0043506 regulation of JUN kinase activity(GO:0043506)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.9 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.9 GO:0001706 endoderm formation(GO:0001706)
0.0 0.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 3.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.5 GO:0001895 retina homeostasis(GO:0001895)
0.0 2.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 2.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.1 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 1.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 2.1 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 2.6 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 1.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.4 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 1.4 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.9 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.0 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.3 GO:0060324 face development(GO:0060324)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0001764 neuron migration(GO:0001764)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 40.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
7.1 21.3 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
3.4 13.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
2.6 15.8 GO:0005927 muscle tendon junction(GO:0005927)
2.3 6.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
2.1 21.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.8 12.8 GO:0001520 outer dense fiber(GO:0001520)
1.8 14.3 GO:0035976 AP1 complex(GO:0035976)
1.8 5.3 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.4 4.2 GO:0005826 actomyosin contractile ring(GO:0005826)
1.4 4.2 GO:0071020 post-spliceosomal complex(GO:0071020)
1.4 8.3 GO:0030991 intraciliary transport particle A(GO:0030991)
1.3 3.9 GO:0044609 DBIRD complex(GO:0044609)
1.3 11.8 GO:0098839 postsynaptic density membrane(GO:0098839)
1.2 8.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.1 8.0 GO:0097013 phagocytic vesicle lumen(GO:0097013)
1.1 10.1 GO:0005638 lamin filament(GO:0005638)
1.1 13.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 7.6 GO:0030061 mitochondrial crista(GO:0030061)
1.1 5.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 14.3 GO:0005858 axonemal dynein complex(GO:0005858)
1.0 3.0 GO:0002139 stereocilia coupling link(GO:0002139)
1.0 4.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.0 9.8 GO:0005677 chromatin silencing complex(GO:0005677)
1.0 4.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 2.8 GO:0043159 acrosomal matrix(GO:0043159)
0.9 5.5 GO:1990130 Iml1 complex(GO:1990130)
0.9 15.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.9 12.1 GO:0031209 SCAR complex(GO:0031209)
0.8 4.2 GO:0089701 U2AF(GO:0089701)
0.8 4.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.8 39.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.8 5.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.8 3.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.8 4.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.7 3.6 GO:0033263 CORVET complex(GO:0033263)
0.7 10.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 3.6 GO:0036128 CatSper complex(GO:0036128)
0.7 3.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.7 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.7 3.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.7 5.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.7 2.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.6 5.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.6 2.5 GO:0070695 FHF complex(GO:0070695)
0.6 15.3 GO:0032982 myosin filament(GO:0032982)
0.6 4.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6 2.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.6 10.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.6 8.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 5.2 GO:0016013 syntrophin complex(GO:0016013)
0.6 7.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.6 18.3 GO:0000795 synaptonemal complex(GO:0000795)
0.5 2.7 GO:0070826 paraferritin complex(GO:0070826)
0.5 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 2.7 GO:0032021 NELF complex(GO:0032021)
0.5 1.6 GO:0097447 dendritic tree(GO:0097447)
0.5 3.5 GO:0044294 dendritic growth cone(GO:0044294)
0.5 5.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.5 1.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.5 2.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.5 1.4 GO:1990393 3M complex(GO:1990393)
0.5 4.7 GO:0000793 condensed chromosome(GO:0000793)
0.4 2.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.4 5.3 GO:0060077 inhibitory synapse(GO:0060077)
0.4 14.0 GO:0042101 T cell receptor complex(GO:0042101)
0.4 1.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.4 3.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 4.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.4 3.7 GO:0070652 HAUS complex(GO:0070652)
0.4 9.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 1.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.4 10.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.4 1.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 1.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 10.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 17.0 GO:0000791 euchromatin(GO:0000791)
0.4 3.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 8.5 GO:0016460 myosin II complex(GO:0016460)
0.4 3.2 GO:0030897 HOPS complex(GO:0030897)
0.3 8.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 2.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 3.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 3.3 GO:0043219 lateral loop(GO:0043219)
0.3 11.4 GO:0042629 mast cell granule(GO:0042629)
0.3 5.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 5.8 GO:0001891 phagocytic cup(GO:0001891)
0.3 5.5 GO:0005811 lipid particle(GO:0005811)
0.3 7.7 GO:0002080 acrosomal membrane(GO:0002080)
0.3 2.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.3 2.8 GO:0032039 integrator complex(GO:0032039)
0.3 23.4 GO:0035580 specific granule lumen(GO:0035580)
0.3 48.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 0.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 21.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 5.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 1.6 GO:0051286 cell tip(GO:0051286)
0.3 20.7 GO:0034707 chloride channel complex(GO:0034707)
0.3 30.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 3.0 GO:0005642 annulate lamellae(GO:0005642)
0.3 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 1.5 GO:0097227 septin complex(GO:0031105) sperm annulus(GO:0097227)
0.2 6.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.2 11.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 25.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 5.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.1 GO:0070847 core mediator complex(GO:0070847)
0.2 1.4 GO:0035859 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.2 3.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 1.1 GO:0034464 BBSome(GO:0034464)
0.2 3.3 GO:0032433 filopodium tip(GO:0032433)
0.2 25.2 GO:0043204 perikaryon(GO:0043204)
0.2 21.0 GO:0031514 motile cilium(GO:0031514)
0.2 2.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.0 GO:0032389 MutLalpha complex(GO:0032389)
0.2 2.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 10.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.8 GO:0072686 mitotic spindle(GO:0072686)
0.2 1.2 GO:0036021 endolysosome lumen(GO:0036021)
0.2 2.3 GO:0005902 microvillus(GO:0005902)
0.2 8.2 GO:0001533 cornified envelope(GO:0001533)
0.2 8.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 7.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 19.2 GO:0072562 blood microparticle(GO:0072562)
0.1 1.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 4.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.6 GO:0036038 MKS complex(GO:0036038)
0.1 3.2 GO:0031674 Z disc(GO:0030018) I band(GO:0031674)
0.1 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.5 GO:0060091 kinocilium(GO:0060091)
0.1 2.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 3.6 GO:0016592 mediator complex(GO:0016592)
0.1 16.3 GO:0055037 recycling endosome(GO:0055037)
0.1 26.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 4.7 GO:0031526 brush border membrane(GO:0031526)
0.1 11.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.1 GO:0005883 neurofilament(GO:0005883)
0.1 2.2 GO:0097546 ciliary base(GO:0097546)
0.1 3.4 GO:0036064 ciliary basal body(GO:0036064)
0.1 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 3.6 GO:0031201 SNARE complex(GO:0031201)
0.1 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 3.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.6 GO:0005861 troponin complex(GO:0005861)
0.1 4.5 GO:0005581 collagen trimer(GO:0005581)
0.1 7.3 GO:0030426 growth cone(GO:0030426)
0.1 0.2 GO:0032420 stereocilium(GO:0032420)
0.1 3.8 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 10.7 GO:0043235 receptor complex(GO:0043235)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 2.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 10.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 0.7 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 3.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.3 GO:0034702 ion channel complex(GO:0034702)
0.0 3.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 38.4 GO:0005615 extracellular space(GO:0005615)
0.0 34.7 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0001726 ruffle(GO:0001726)
0.0 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.2 24.6 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
5.3 15.9 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
4.6 18.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
4.0 40.5 GO:0001851 complement component C3b binding(GO:0001851)
3.6 10.9 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
3.6 14.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
3.5 14.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
3.1 9.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
2.9 8.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.8 14.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
2.8 8.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
2.7 10.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
2.5 10.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
2.4 12.0 GO:0004771 sterol esterase activity(GO:0004771)
2.4 7.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
2.3 2.3 GO:0001855 complement component C4b binding(GO:0001855)
2.2 31.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
2.2 13.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
2.2 6.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
2.2 6.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.0 6.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
2.0 8.1 GO:0070051 fibrinogen binding(GO:0070051)
2.0 8.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.9 9.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.8 5.5 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.8 9.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.8 5.4 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.7 8.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.7 8.3 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
1.7 5.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.6 22.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.5 6.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
1.5 4.5 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.5 5.9 GO:0032810 sterol response element binding(GO:0032810)
1.5 5.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.4 4.3 GO:0004040 amidase activity(GO:0004040)
1.4 4.1 GO:0048030 disaccharide binding(GO:0048030)
1.4 5.5 GO:0035473 lipase binding(GO:0035473)
1.3 4.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
1.3 4.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.3 5.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.3 23.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.3 22.8 GO:0019992 diacylglycerol binding(GO:0019992)
1.2 3.7 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.2 7.3 GO:0003796 lysozyme activity(GO:0003796)
1.2 4.8 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.2 3.6 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
1.2 3.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.1 4.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.1 11.5 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
1.1 3.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.1 4.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.1 57.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.1 3.3 GO:0004802 transketolase activity(GO:0004802)
1.1 7.5 GO:0043208 glycosphingolipid binding(GO:0043208)
1.1 9.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.1 6.4 GO:0070182 DNA polymerase binding(GO:0070182)
1.0 6.3 GO:0042610 CD8 receptor binding(GO:0042610)
1.0 4.1 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
1.0 5.0 GO:0031708 endothelin B receptor binding(GO:0031708)
1.0 1.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
1.0 5.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
1.0 2.9 GO:0004951 cholecystokinin receptor activity(GO:0004951)
1.0 3.9 GO:0008410 CoA-transferase activity(GO:0008410)
1.0 7.7 GO:0034235 GPI anchor binding(GO:0034235)
0.9 3.8 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.9 2.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.9 3.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 4.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.9 3.7 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.9 9.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.9 2.8 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.9 9.2 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9 3.7 GO:0031685 adenosine receptor binding(GO:0031685)
0.9 3.7 GO:0016936 galactoside binding(GO:0016936)
0.9 3.6 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.9 3.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.9 2.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.9 13.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.9 2.6 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.9 4.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.9 4.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.8 4.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.8 18.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.8 1.7 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.8 4.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.8 4.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.8 2.4 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.8 2.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.8 4.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.8 2.4 GO:0031877 somatostatin receptor binding(GO:0031877)
0.8 3.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.8 15.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 7.6 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.7 6.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.7 6.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.7 3.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.7 5.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.7 2.2 GO:0032089 NACHT domain binding(GO:0032089)
0.7 7.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 4.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.7 15.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.7 3.3 GO:0050436 microfibril binding(GO:0050436)
0.7 2.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.7 10.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.6 1.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.6 6.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.6 10.8 GO:0005542 folic acid binding(GO:0005542)
0.6 9.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.6 10.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 1.9 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.6 3.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.6 7.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.6 2.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.6 6.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.6 1.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.6 3.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.6 9.2 GO:0015643 toxic substance binding(GO:0015643)
0.6 2.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.6 3.5 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.6 4.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.6 7.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.6 5.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.6 2.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.6 1.7 GO:0019959 interleukin-8 binding(GO:0019959)
0.5 2.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 2.7 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.5 6.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.5 2.2 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.5 2.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.5 4.3 GO:0019863 IgE binding(GO:0019863)
0.5 5.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.5 3.6 GO:0050733 RS domain binding(GO:0050733)
0.5 2.0 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 3.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.5 5.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5 3.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 8.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.5 3.7 GO:0005497 androgen binding(GO:0005497)
0.5 2.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 3.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.5 5.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.5 2.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.5 1.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.5 2.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.5 12.7 GO:0005521 lamin binding(GO:0005521)
0.5 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 5.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.4 3.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 25.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 5.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.4 2.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 7.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 5.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.4 1.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 7.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 22.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 3.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 2.5 GO:0004630 phospholipase D activity(GO:0004630)
0.4 3.7 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.4 9.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 5.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 4.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.4 2.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.4 1.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 0.8 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.4 2.4 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.4 7.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 6.2 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.4 3.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.4 6.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 17.2 GO:0070412 R-SMAD binding(GO:0070412)
0.4 2.6 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.4 6.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 1.1 GO:0070984 SET domain binding(GO:0070984)
0.4 1.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 2.8 GO:0004875 complement receptor activity(GO:0004875)
0.4 4.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.4 5.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.4 3.9 GO:0097016 L27 domain binding(GO:0097016)
0.4 1.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 1.1 GO:0003883 CTP synthase activity(GO:0003883)
0.4 2.8 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 2.8 GO:0048495 Roundabout binding(GO:0048495)
0.3 1.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 1.0 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 6.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 2.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 1.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 12.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 1.6 GO:0046625 sphingolipid binding(GO:0046625)
0.3 5.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.3 11.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 1.6 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.3 1.6 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.3 13.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 0.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 2.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 7.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 6.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 16.7 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.3 1.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 4.7 GO:0071837 HMG box domain binding(GO:0071837)
0.3 2.0 GO:0051525 NFAT protein binding(GO:0051525)
0.3 7.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 5.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 4.8 GO:0031005 filamin binding(GO:0031005)
0.3 2.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 2.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 0.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.3 1.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 0.8 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.3 1.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.3 2.2 GO:0003696 satellite DNA binding(GO:0003696)
0.3 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 6.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 7.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 2.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 3.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 9.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.3 68.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 3.3 GO:0051787 misfolded protein binding(GO:0051787)
0.3 9.6 GO:0042169 SH2 domain binding(GO:0042169)
0.3 1.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 4.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 3.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 12.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.7 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 2.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 9.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 2.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 13.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.6 GO:0030911 TPR domain binding(GO:0030911)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 2.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2 5.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 3.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 4.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 4.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 1.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 2.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 2.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.1 GO:0051373 FATZ binding(GO:0051373)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 4.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 4.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.5 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 7.2 GO:0050699 WW domain binding(GO:0050699)
0.2 4.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 5.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 6.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 3.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 13.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.2 8.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 2.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 20.4 GO:0003823 antigen binding(GO:0003823)
0.2 8.5 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 0.5 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 1.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 1.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 3.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 2.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 2.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.3 GO:0004954 prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.2 0.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 1.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0005113 patched binding(GO:0005113)
0.1 1.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 3.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 6.6 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 9.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 4.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.6 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 9.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 5.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 5.3 GO:0017046 peptide hormone binding(GO:0017046)
0.1 3.2 GO:0008066 glutamate receptor activity(GO:0008066)
0.1 1.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 2.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 6.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.5 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.5 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.3 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 10.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 3.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 6.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 34.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 3.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 2.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 4.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.4 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 1.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 3.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 1.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 4.4 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 0.2 GO:0005549 odorant binding(GO:0005549)
0.1 1.2 GO:0010181 FMN binding(GO:0010181)
0.1 0.7 GO:0005372 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.3 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.1 83.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.5 GO:0099589 serotonin receptor activity(GO:0099589)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.7 GO:0043621 protein self-association(GO:0043621)
0.1 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 11.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 2.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 2.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0003774 motor activity(GO:0003774)
0.0 2.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 5.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 8.7 GO:0004888 transmembrane signaling receptor activity(GO:0004888)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 59.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
1.4 57.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.8 15.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 16.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 6.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 28.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.5 1.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.5 2.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 44.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.5 11.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 15.3 ST GA12 PATHWAY G alpha 12 Pathway
0.4 11.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 22.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 13.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.4 2.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 4.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 27.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 12.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 10.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 6.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 4.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 10.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 4.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 5.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 5.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 9.5 PID IL23 PATHWAY IL23-mediated signaling events
0.3 11.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.2 4.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 11.7 PID ATM PATHWAY ATM pathway
0.2 6.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 5.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 4.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 2.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 3.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 42.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 21.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 6.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 26.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.7 PID FOXO PATHWAY FoxO family signaling
0.1 3.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.0 PID ENDOTHELIN PATHWAY Endothelins
0.1 4.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 7.4 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.8 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.4 ST GA13 PATHWAY G alpha 13 Pathway
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 1.6 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 3.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.1 29.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 3.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 4.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 24.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.9 19.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.9 56.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.9 6.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.9 17.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.8 4.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.8 61.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.8 8.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.8 9.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.7 11.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.7 13.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 7.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 14.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.6 9.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 2.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.6 6.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.5 10.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.5 8.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 10.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 29.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 11.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 9.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5 14.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 4.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.4 31.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.4 8.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.4 7.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.4 5.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 4.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 19.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.4 4.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 137.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.4 16.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 6.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 3.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 9.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 2.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.3 15.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 9.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 5.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.3 6.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 24.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 9.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 4.2 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.2 4.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 4.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 13.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.4 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.2 4.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 5.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 4.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 10.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 5.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 9.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 8.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 8.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 3.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.2 REACTOME MEIOSIS Genes involved in Meiosis
0.1 2.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 5.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 16.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 9.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 5.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 4.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 2.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.9 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.1 2.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 3.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 4.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 2.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 6.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression