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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for TBX5

Z-value: 1.45

Motif logo

Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
ENSG00000089225.15 T-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX5hg19_v2_chr12_-_114841703_1148417260.471.2e-13Click!

Activity profile of TBX5 motif

Sorted Z-values of TBX5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_5248294 30.90 ENST00000335295.4
hemoglobin, beta
chr14_+_75746781 30.36 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_167453493 21.49 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr16_+_2588012 20.02 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr1_-_35325400 18.28 ENST00000521580.2
small integral membrane protein 12
chr14_+_75745477 18.15 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FBJ murine osteosarcoma viral oncogene homolog
chr12_-_45270077 17.47 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr12_-_45270151 17.44 ENST00000429094.2
NEL-like 2 (chicken)
chr5_-_127418755 16.68 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
chr11_+_73358594 16.13 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_-_120133661 15.90 ENST00000503243.1
ENST00000326780.3
Uncharacterized protein
chr2_+_68962014 15.24 ENST00000467265.1
Rho GTPase activating protein 25
chr3_-_18466026 14.65 ENST00000417717.2
SATB homeobox 1
chr18_-_52969844 14.51 ENST00000561831.3
transcription factor 4
chr17_+_77681075 14.51 ENST00000397549.2
CTD-2116F7.1
chr19_-_39108568 14.43 ENST00000586296.1
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_175869936 14.31 ENST00000409900.3
chimerin 1
chr4_+_166300084 13.49 ENST00000402744.4
carboxypeptidase E
chr5_+_54320078 13.31 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr10_-_99531709 13.24 ENST00000266066.3
secreted frizzled-related protein 5
chr17_+_34431212 12.90 ENST00000394495.1
chemokine (C-C motif) ligand 4
chr2_+_68961934 12.78 ENST00000409202.3
Rho GTPase activating protein 25
chr2_+_68961905 12.42 ENST00000295381.3
Rho GTPase activating protein 25
chr16_+_2587998 12.18 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr4_-_176733897 12.09 ENST00000393658.2
glycoprotein M6A
chr4_+_158142750 12.09 ENST00000505888.1
ENST00000449365.1
glutamate receptor, ionotropic, AMPA 2
chr13_-_36429763 11.29 ENST00000379893.1
doublecortin-like kinase 1
chr2_-_175870085 10.92 ENST00000409156.3
chimerin 1
chr17_+_27055798 10.84 ENST00000268766.6
NIMA-related kinase 8
chr16_+_2587965 10.65 ENST00000342085.4
ENST00000566659.1
3-phosphoinositide dependent protein kinase-1
chrX_-_106960285 10.61 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr22_-_51016433 10.53 ENST00000405237.3
carnitine palmitoyltransferase 1B (muscle)
chr17_+_34430980 10.49 ENST00000250151.4
chemokine (C-C motif) ligand 4
chrX_+_56259316 9.99 ENST00000468660.1
Kruppel-like factor 8
chr19_-_49622348 9.76 ENST00000408991.2
chromosome 19 open reading frame 73
chr8_-_9760839 9.70 ENST00000519461.1
ENST00000517675.1
long intergenic non-protein coding RNA 599
chr11_-_72385437 9.62 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr1_-_169680745 9.60 ENST00000236147.4
selectin L
chr2_+_103089756 9.53 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr17_-_46507567 9.49 ENST00000584924.1
src kinase associated phosphoprotein 1
chr12_+_8234807 9.37 ENST00000339754.5
NECAP endocytosis associated 1
chr1_+_101702417 9.18 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr10_-_102279586 9.12 ENST00000370345.3
ENST00000451524.1
ENST00000370329.5
SEC31 homolog B (S. cerevisiae)
chrX_-_106959631 9.09 ENST00000486554.1
ENST00000372390.4
TSC22 domain family, member 3
chr7_+_97361218 9.00 ENST00000319273.5
tachykinin, precursor 1
chr1_-_241520525 8.93 ENST00000366565.1
regulator of G-protein signaling 7
chr11_-_59383617 8.85 ENST00000263847.1
oxysterol binding protein
chr19_-_10420459 8.70 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chrY_+_15016013 8.66 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr7_+_5919458 8.36 ENST00000416608.1
oncomodulin
chr22_-_51016846 8.35 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr1_-_15735925 8.32 ENST00000427824.1
RP3-467K16.4
chrX_-_49056635 8.10 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
synaptophysin
chr22_-_31688431 8.07 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr2_-_89399845 8.03 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr3_-_49459865 8.03 ENST00000427987.1
aminomethyltransferase
chr1_+_1981890 8.02 ENST00000378567.3
ENST00000468310.1
protein kinase C, zeta
chr11_-_18656028 7.99 ENST00000336349.5
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr9_-_93405352 7.95 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chrY_+_15016725 7.90 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr19_+_50380682 7.74 ENST00000221543.5
TBC1 domain family, member 17
chr19_+_50380917 7.72 ENST00000535102.2
TBC1 domain family, member 17
chr5_-_134914673 7.58 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr14_-_24911971 7.56 ENST00000555365.1
ENST00000399395.3
short chain dehydrogenase/reductase family 39U, member 1
chr1_-_27961720 7.56 ENST00000545953.1
ENST00000374005.3
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr7_-_130080818 7.56 ENST00000343969.5
ENST00000541543.1
ENST00000489512.1
centrosomal protein 41kDa
chr1_+_11866207 7.54 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chrX_+_129473859 7.50 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr19_-_4302375 7.49 ENST00000600114.1
ENST00000600349.1
ENST00000595645.1
ENST00000301272.2
transmembrane and immunoglobulin domain containing 2
chr11_+_117947782 7.29 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr16_-_4465886 7.17 ENST00000539968.1
coronin 7
chr17_+_53343577 7.16 ENST00000573945.1
hepatic leukemia factor
chr3_-_49459878 7.16 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
aminomethyltransferase
chr17_-_46507537 7.15 ENST00000336915.6
src kinase associated phosphoprotein 1
chr1_+_168148273 7.03 ENST00000367830.3
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr15_+_81589254 6.98 ENST00000394652.2
interleukin 16
chr17_-_26220366 6.97 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr7_+_97361388 6.97 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr22_+_46481861 6.93 ENST00000360737.3
hsa-mir-4763
chr14_-_24911868 6.86 ENST00000554698.1
short chain dehydrogenase/reductase family 39U, member 1
chr2_+_189156638 6.85 ENST00000410051.1
GULP, engulfment adaptor PTB domain containing 1
chr8_-_18666360 6.83 ENST00000286485.8
pleckstrin and Sec7 domain containing 3
chr19_-_39108643 6.82 ENST00000396857.2
mitogen-activated protein kinase kinase kinase kinase 1
chr19_-_14016877 6.81 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
chromosome 19 open reading frame 57
chr6_-_33239712 6.72 ENST00000436044.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr1_-_25256368 6.68 ENST00000308873.6
runt-related transcription factor 3
chrX_-_99987088 6.67 ENST00000372981.1
ENST00000263033.5
synaptotagmin-like 4
chr16_-_31454346 6.64 ENST00000564218.1
ENST00000315678.5
zinc finger protein 843
chr20_+_48884002 6.62 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr16_+_30662360 6.56 ENST00000542965.2
proline rich 14
chr7_+_100450328 6.53 ENST00000540482.1
ENST00000418037.1
ENST00000428758.1
ENST00000275729.3
ENST00000415287.1
ENST00000354161.3
ENST00000416675.1
solute carrier family 12, member 9
chr1_-_20250110 6.53 ENST00000375116.3
phospholipase A2, group IIE
chr7_-_137028534 6.51 ENST00000348225.2
pleiotrophin
chr11_-_123525289 6.50 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
sodium channel, voltage-gated, type III, beta subunit
chr15_-_41099648 6.43 ENST00000220496.4
DnaJ (Hsp40) homolog, subfamily C, member 17
chr15_-_71055878 6.36 ENST00000322954.6
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr19_-_39108552 6.33 ENST00000591517.1
mitogen-activated protein kinase kinase kinase kinase 1
chr7_-_137028498 6.26 ENST00000393083.2
pleiotrophin
chr1_+_16062820 6.26 ENST00000294454.5
solute carrier family 25, member 34
chr1_-_151119087 6.23 ENST00000341697.3
ENST00000368914.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr12_-_111021110 6.20 ENST00000354300.3
PTC7 protein phosphatase homolog (S. cerevisiae)
chr3_+_35722487 6.10 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr13_+_115047097 6.03 ENST00000351487.5
UPF3 regulator of nonsense transcripts homolog A (yeast)
chr22_-_31688381 6.03 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr3_-_101232019 5.97 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr7_-_100253993 5.94 ENST00000461605.1
ENST00000160382.5
actin-like 6B
chr1_+_179712298 5.89 ENST00000341785.4
family with sequence similarity 163, member A
chr8_+_123793633 5.87 ENST00000314393.4
zinc fingers and homeoboxes 2
chr11_+_65479702 5.87 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
K(lysine) acetyltransferase 5
chr9_+_87285539 5.84 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr21_+_38445539 5.82 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr12_+_112563303 5.75 ENST00000412615.2
TRAF-type zinc finger domain containing 1
chr6_+_44184653 5.60 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr20_-_45035198 5.60 ENST00000372176.1
engulfment and cell motility 2
chr6_-_41168920 5.59 ENST00000483722.1
triggering receptor expressed on myeloid cells-like 2
chr2_-_89521942 5.58 ENST00000482769.1
immunoglobulin kappa variable 2-28
chrX_-_70329118 5.57 ENST00000374188.3
interleukin 2 receptor, gamma
chr17_-_40333099 5.53 ENST00000607371.1
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_-_21988558 5.49 ENST00000312841.8
hair growth associated
chr11_+_1940786 5.45 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
troponin T type 3 (skeletal, fast)
chr1_+_13910194 5.42 ENST00000376057.4
ENST00000510906.1
podoplanin
chrX_+_76709648 5.36 ENST00000439435.1
fibroblast growth factor 16
chr17_-_73892992 5.33 ENST00000540128.1
ENST00000269383.3
tripartite motif containing 65
chr20_+_57875658 5.28 ENST00000371025.3
endothelin 3
chr6_+_292051 5.20 ENST00000344450.5
dual specificity phosphatase 22
chr5_-_131347583 5.19 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr20_+_57875457 5.15 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr5_+_66124590 5.12 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr12_+_57853918 5.11 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI family zinc finger 1
chr2_-_152589670 5.05 ENST00000604864.1
ENST00000603639.1
nebulin
chr7_+_96634850 5.01 ENST00000518156.2
distal-less homeobox 6
chr6_+_39760129 5.00 ENST00000274867.4
dishevelled associated activator of morphogenesis 2
chr2_+_89998789 5.00 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr12_+_112563335 4.99 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr12_+_7055767 4.97 ENST00000447931.2
protein tyrosine phosphatase, non-receptor type 6
chr17_-_61959202 4.96 ENST00000449787.2
ENST00000456543.2
ENST00000423893.2
ENST00000332800.7
growth hormone 2
chr15_+_89182156 4.94 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr7_-_74221288 4.93 ENST00000451013.2
GTF2I repeat domain containing 2
chr22_-_51017084 4.92 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chrX_-_130423200 4.83 ENST00000361420.3
immunoglobulin superfamily, member 1
chr11_-_119252425 4.82 ENST00000260187.2
ubiquitin specific peptidase 2
chr7_+_30951461 4.81 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr11_-_45939565 4.81 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr1_-_207095324 4.80 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr11_+_117947724 4.77 ENST00000534111.1
transmembrane protease, serine 4
chr22_-_38699003 4.76 ENST00000451964.1
casein kinase 1, epsilon
chr10_+_76586348 4.74 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr15_+_81489213 4.73 ENST00000559383.1
ENST00000394660.2
interleukin 16
chr19_-_45826125 4.69 ENST00000221476.3
creatine kinase, muscle
chr9_-_79307096 4.67 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr6_+_127588020 4.67 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr2_+_183943464 4.65 ENST00000354221.4
dual specificity phosphatase 19
chr6_-_33239612 4.64 ENST00000482399.1
ENST00000445902.2
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr17_-_61996160 4.61 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
growth hormone 1
chr2_-_152118352 4.56 ENST00000331426.5
RNA binding motif protein 43
chr17_-_61996192 4.52 ENST00000392824.4
chorionic somatomammotropin hormone-like 1
chr1_+_55464600 4.51 ENST00000371265.4
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr7_+_40174565 4.50 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
succinylCoA:glutarate-CoA transferase
chr7_+_86974974 4.45 ENST00000419147.2
carnitine O-octanoyltransferase
chr1_-_169863016 4.43 ENST00000367772.4
ENST00000367771.6
SCY1-like 3 (S. cerevisiae)
chr17_-_35969409 4.29 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
synergin, gamma
chr11_+_46354455 4.28 ENST00000343674.6
diacylglycerol kinase, zeta
chr4_-_141348789 4.28 ENST00000414773.1
calmegin
chr16_-_53537105 4.23 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKT interacting protein
chr17_+_30814707 4.19 ENST00000584792.1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_+_29237354 4.16 ENST00000546235.1
chimerin 2
chr11_-_58345569 4.14 ENST00000528954.1
ENST00000528489.1
leupaxin
chr11_+_1940925 4.14 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr1_+_184356188 4.13 ENST00000235307.6
chromosome 1 open reading frame 21
chr12_+_7055631 4.13 ENST00000543115.1
ENST00000399448.1
protein tyrosine phosphatase, non-receptor type 6
chr19_+_18723660 4.13 ENST00000262817.3
transmembrane protein 59-like
chr19_-_51875894 4.11 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr6_+_83777374 4.10 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr19_+_48867652 4.09 ENST00000344846.2
synaptogyrin 4
chr1_+_19923454 4.07 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr12_-_121342170 4.06 ENST00000353487.2
signal peptide peptidase like 3
chr17_-_61988556 4.05 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
chorionic somatomammotropin hormone-like 1
chr15_+_89181974 4.04 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr12_-_371994 4.03 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
solute carrier family 6 (neurotransmitter transporter), member 13
chr14_+_21467414 3.98 ENST00000554422.1
ENST00000298681.4
solute carrier family 39 (zinc transporter), member 2
chrX_+_21392553 3.98 ENST00000279451.4
connector enhancer of kinase suppressor of Ras 2
chr17_+_58755184 3.97 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr6_-_13487784 3.96 ENST00000379287.3
glucose-fructose oxidoreductase domain containing 1
chr16_+_640201 3.96 ENST00000563109.1
RAB40C, member RAS oncogene family
chr7_-_138666053 3.96 ENST00000440172.1
ENST00000422774.1
KIAA1549
chrX_+_69642881 3.95 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
glycerophosphodiester phosphodiesterase domain containing 2
chr19_-_3500635 3.89 ENST00000250937.3
deoxyhypusine hydroxylase/monooxygenase
chr7_-_71801980 3.89 ENST00000329008.5
calneuron 1
chr2_-_217724767 3.88 ENST00000236979.2
transition protein 1 (during histone to protamine replacement)
chr2_+_242127924 3.84 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr15_-_58357932 3.79 ENST00000347587.3
aldehyde dehydrogenase 1 family, member A2
chr3_-_61237050 3.76 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
fragile histidine triad
chr3_-_49726486 3.75 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_-_18937726 3.71 ENST00000389467.3
ENST00000446231.2
SMG1 phosphatidylinositol 3-kinase-related kinase
chrX_-_130423386 3.68 ENST00000370903.3
immunoglobulin superfamily, member 1
chr3_-_3221358 3.67 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
cereblon
chr15_+_89182178 3.66 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr8_-_53322303 3.64 ENST00000276480.7
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr11_-_47470591 3.61 ENST00000524487.1
receptor-associated protein of the synapse
chr1_+_13910479 3.61 ENST00000509009.1
podoplanin

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 35.7 GO:0030185 nitric oxide transport(GO:0030185)
6.4 51.4 GO:0001661 conditioned taste aversion(GO:0001661)
5.3 16.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
4.7 14.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
4.4 31.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
4.3 42.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
4.3 12.8 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
4.2 12.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.8 11.4 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
3.5 10.5 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
3.4 10.3 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
3.3 13.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
3.2 9.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
3.1 9.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
3.0 15.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.0 3.0 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
2.7 8.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
2.7 13.5 GO:0030070 insulin processing(GO:0030070)
2.6 10.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
2.5 34.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
2.5 2.5 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
2.5 19.7 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
2.3 9.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
1.6 6.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
1.6 6.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.5 7.6 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
1.4 4.2 GO:0021586 pons maturation(GO:0021586)
1.3 8.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
1.3 3.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
1.3 5.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
1.3 5.0 GO:0007525 somatic muscle development(GO:0007525)
1.3 7.6 GO:0018095 protein polyglutamylation(GO:0018095)
1.2 27.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.2 23.8 GO:0006853 carnitine shuttle(GO:0006853)
1.2 3.5 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.1 3.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
1.1 7.5 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
1.1 11.6 GO:0035330 regulation of hippo signaling(GO:0035330)
1.0 1.0 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
1.0 2.9 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.9 14.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.9 6.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.9 2.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.9 8.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.9 6.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.9 2.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.9 10.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 2.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.8 4.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.8 3.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 5.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.8 5.4 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.7 3.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 5.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 25.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.7 2.7 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.7 2.7 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.6 6.4 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.6 3.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.6 0.6 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.6 4.9 GO:0002051 osteoblast fate commitment(GO:0002051)
0.6 9.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 1.7 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.6 8.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.6 1.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.5 6.0 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.5 7.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.5 2.7 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.5 11.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.5 3.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5 2.1 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.5 1.6 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.5 1.5 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.5 2.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.5 9.8 GO:0044117 growth of symbiont in host(GO:0044117) regulation of growth of symbiont in host(GO:0044126)
0.5 7.7 GO:0045475 locomotor rhythm(GO:0045475)
0.5 2.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.5 1.9 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5 2.4 GO:0002442 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.5 3.6 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.5 11.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.5 11.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 16.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 1.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.4 9.0 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.4 4.7 GO:0006600 creatine metabolic process(GO:0006600)
0.4 7.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.4 3.8 GO:0035799 ureter maturation(GO:0035799)
0.4 4.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 2.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 1.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.4 3.6 GO:2001300 ductus arteriosus closure(GO:0097070) lipoxin metabolic process(GO:2001300)
0.4 7.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 2.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 1.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.4 3.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 1.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.4 1.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.4 6.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 3.9 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.3 2.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 7.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 1.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 5.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 2.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 0.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 3.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 5.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.3 1.1 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.3 3.9 GO:0090527 actin filament reorganization(GO:0090527)
0.3 4.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.3 4.0 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.3 6.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 5.7 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 4.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 1.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3 2.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 1.8 GO:1903760 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 4.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 10.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 20.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 2.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 21.8 GO:0007422 peripheral nervous system development(GO:0007422)
0.2 4.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 2.2 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.2 17.0 GO:0007602 phototransduction(GO:0007602)
0.2 6.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.2 3.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 4.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 0.9 GO:1904379 maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 10.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.2 6.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 10.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 0.8 GO:0002215 defense response to nematode(GO:0002215)
0.2 1.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.2 7.6 GO:0048599 oocyte development(GO:0048599)
0.2 4.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.3 GO:0051775 response to redox state(GO:0051775)
0.2 2.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 10.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 0.6 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.2 2.7 GO:0015732 prostaglandin transport(GO:0015732)
0.2 1.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 3.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 1.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) negative regulation of telomerase activity(GO:0051974)
0.1 1.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1 4.9 GO:0010107 potassium ion import(GO:0010107)
0.1 6.4 GO:1901998 toxin transport(GO:1901998)
0.1 10.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 46.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 0.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 3.2 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 17.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.5 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 6.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 2.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 10.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 1.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 3.2 GO:0048536 spleen development(GO:0048536)
0.1 4.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 4.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.7 GO:0016180 snRNA processing(GO:0016180)
0.1 4.1 GO:0014047 glutamate secretion(GO:0014047)
0.1 2.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 2.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 16.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 2.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.6 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 5.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 4.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 4.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 4.3 GO:0009060 aerobic respiration(GO:0009060)
0.1 3.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.8 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 1.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.6 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 5.0 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 6.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 1.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 5.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 3.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 6.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 5.1 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 4.0 GO:0051028 mRNA transport(GO:0051028)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 2.3 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 3.2 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 2.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.0 2.1 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 2.4 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 1.2 GO:0070268 cornification(GO:0070268)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 30.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
6.1 48.5 GO:0035976 AP1 complex(GO:0035976)
2.8 11.4 GO:1990745 EARP complex(GO:1990745)
2.5 7.5 GO:0070195 growth hormone receptor complex(GO:0070195)
2.4 12.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
2.3 9.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.6 4.8 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.1 13.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.1 4.2 GO:0070695 FHF complex(GO:0070695)
1.0 4.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.0 10.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.0 8.0 GO:0045179 apical cortex(GO:0045179)
0.8 9.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 16.6 GO:0042101 T cell receptor complex(GO:0042101)
0.6 3.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.6 4.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 4.1 GO:0061617 MICOS complex(GO:0061617)
0.6 4.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5 12.1 GO:0044295 axonal growth cone(GO:0044295)
0.5 12.3 GO:0005861 troponin complex(GO:0005861)
0.5 8.1 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 4.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 64.0 GO:0043204 perikaryon(GO:0043204)
0.4 6.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 15.9 GO:0097546 ciliary base(GO:0097546)
0.4 3.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 14.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 8.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.3 3.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 2.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 7.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 5.9 GO:0071565 nBAF complex(GO:0071565)
0.2 4.9 GO:0042588 zymogen granule(GO:0042588)
0.2 1.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.2 2.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 6.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 2.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 2.3 GO:0043235 receptor complex(GO:0043235)
0.2 6.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2 3.0 GO:0005916 fascia adherens(GO:0005916)
0.2 10.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.7 GO:0032039 integrator complex(GO:0032039)
0.2 8.1 GO:0030662 coated vesicle membrane(GO:0030662)
0.2 1.8 GO:0043219 lateral loop(GO:0043219)
0.2 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 9.0 GO:0031904 endosome lumen(GO:0031904)
0.2 10.4 GO:0031594 neuromuscular junction(GO:0031594)
0.2 4.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 7.8 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0060198 clathrin-sculpted vesicle(GO:0060198) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 3.4 GO:0046930 pore complex(GO:0046930)
0.1 2.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 13.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 9.7 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 7.6 GO:0043195 terminal bouton(GO:0043195)
0.1 9.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 18.4 GO:0055037 recycling endosome(GO:0055037)
0.1 2.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 10.0 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 9.5 GO:0005581 collagen trimer(GO:0005581)
0.1 17.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 11.8 GO:0016605 PML body(GO:0016605)
0.1 4.1 GO:0002102 podosome(GO:0002102)
0.1 12.5 GO:0030018 Z disc(GO:0030018)
0.1 3.6 GO:0045095 keratin filament(GO:0045095)
0.1 19.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 25.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 19.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 17.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 9.1 GO:0030016 myofibril(GO:0030016)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 4.9 GO:0036064 ciliary basal body(GO:0036064)
0.1 4.6 GO:0042383 sarcolemma(GO:0042383)
0.1 3.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 10.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.1 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0098794 postsynapse(GO:0098794)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.2 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 1.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 41.9 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.3 42.8 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
5.1 30.9 GO:0030492 hemoglobin binding(GO:0030492)
4.8 23.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
4.2 12.6 GO:0008859 exoribonuclease II activity(GO:0008859)
3.8 15.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
3.3 23.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
3.2 12.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
2.5 7.5 GO:0005148 prolactin receptor binding(GO:0005148)
2.4 9.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
2.2 19.7 GO:0043426 MRF binding(GO:0043426)
2.1 6.4 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
2.1 10.4 GO:0031708 endothelin B receptor binding(GO:0031708)
1.9 7.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.9 5.6 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
1.6 9.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
1.6 4.8 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.6 4.7 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.6 18.8 GO:0046625 sphingolipid binding(GO:0046625)
1.5 27.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.5 7.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
1.4 20.2 GO:0042043 neurexin family protein binding(GO:0042043)
1.4 4.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.4 10.9 GO:0034711 inhibin binding(GO:0034711)
1.3 4.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.3 6.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.3 3.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.3 8.8 GO:0008142 oxysterol binding(GO:0008142)
1.1 3.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
1.1 14.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.0 3.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
1.0 4.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.0 12.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.0 3.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 9.5 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.0 2.9 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.0 48.5 GO:0070412 R-SMAD binding(GO:0070412)
0.9 4.7 GO:0004111 creatine kinase activity(GO:0004111)
0.9 2.7 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.9 8.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.9 3.6 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.8 5.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.8 8.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.8 4.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.8 1.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.7 8.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.7 9.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.7 2.1 GO:0070052 collagen V binding(GO:0070052)
0.7 4.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.6 14.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.6 27.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 11.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 3.0 GO:0071253 connexin binding(GO:0071253)
0.6 2.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 2.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.6 13.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 2.3 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.6 14.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.5 1.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.5 10.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.5 3.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5 2.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.5 5.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 1.5 GO:0019981 interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.5 16.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 1.9 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 18.4 GO:0042169 SH2 domain binding(GO:0042169)
0.4 1.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.4 3.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 7.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 3.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 2.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.4 1.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 4.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 5.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 0.9 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 6.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.3 2.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 2.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 3.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 3.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 6.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 2.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 2.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 11.3 GO:0015026 coreceptor activity(GO:0015026)
0.2 27.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 1.7 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 4.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 3.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 9.4 GO:0008009 chemokine activity(GO:0008009)
0.2 2.7 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 2.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 2.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 2.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 4.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 6.5 GO:0005518 collagen binding(GO:0005518)
0.2 2.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.2 0.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 2.7 GO:0031014 troponin T binding(GO:0031014)
0.2 3.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.2 10.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 13.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 5.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 8.3 GO:0030332 cyclin binding(GO:0030332)
0.2 7.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 5.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 6.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 4.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 2.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467) voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 1.8 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 14.3 GO:0019905 syntaxin binding(GO:0019905)
0.1 10.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 45.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.0 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 2.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 11.4 GO:0005179 hormone activity(GO:0005179)
0.1 0.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 12.1 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.4 GO:0016248 channel inhibitor activity(GO:0016248)
0.1 20.4 GO:0003823 antigen binding(GO:0003823)
0.1 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.8 GO:0070888 E-box binding(GO:0070888)
0.1 2.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.3 GO:0031433 telethonin binding(GO:0031433)
0.1 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 3.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.9 GO:0020037 heme binding(GO:0020037)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 2.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.1 GO:0009055 electron carrier activity(GO:0009055)
0.0 2.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.9 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 48.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.7 76.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
1.3 2.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.5 12.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 30.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.4 12.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 32.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 11.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.3 19.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 9.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 19.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 11.4 PID ENDOTHELIN PATHWAY Endothelins
0.2 3.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 9.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 1.5 PID IL27 PATHWAY IL27-mediated signaling events
0.2 4.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 4.9 PID FGF PATHWAY FGF signaling pathway
0.1 4.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 5.2 PID SHP2 PATHWAY SHP2 signaling
0.1 49.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 15.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.0 PID TNF PATHWAY TNF receptor signaling pathway
0.1 4.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 10.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 48.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
1.3 42.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.8 23.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.7 16.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.6 15.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.6 15.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.5 7.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.4 27.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 8.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 66.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 2.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.4 2.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 4.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 11.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.3 3.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 7.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 2.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 4.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 6.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 2.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 6.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 6.4