Project
GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for TEAD4
Z-value: 1.06
Motif logo
Transcription factors associated with TEAD4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TEAD4
|
ENSG00000197905.4 | TEA domain transcription factor 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TEAD4 | hg19_v2_chr12_+_3068544_3068597, hg19_v2_chr12_+_3068466_3068496, hg19_v2_chr12_+_3069037_3069119 | -0.46 | 6.7e-13 | Click! |
Activity profile of TEAD4 motif
Sorted Z-values of TEAD4 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_91539918 | 24.34 |
ENST00000548218.1
|
DCN
|
decorin |
| chr17_-_29624343 | 21.96 |
ENST00000247271.4
|
OMG
|
oligodendrocyte myelin glycoprotein |
| chr9_-_104249400 | 18.27 |
ENST00000374848.3
|
TMEM246
|
transmembrane protein 246 |
| chr1_+_153004800 | 16.44 |
ENST00000392661.3
|
SPRR1B
|
small proline-rich protein 1B |
| chr8_-_27115931 | 14.49 |
ENST00000523048.1
|
STMN4
|
stathmin-like 4 |
| chr19_+_35630022 | 14.07 |
ENST00000589209.1
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr7_-_37024665 | 14.03 |
ENST00000396040.2
|
ELMO1
|
engulfment and cell motility 1 |
| chr5_+_173472607 | 13.91 |
ENST00000303177.3
ENST00000519867.1 |
NSG2
|
Neuron-specific protein family member 2 |
| chr12_+_79258547 | 13.51 |
ENST00000457153.2
|
SYT1
|
synaptotagmin I |
| chr15_+_81475047 | 13.04 |
ENST00000559388.1
|
IL16
|
interleukin 16 |
| chr12_+_79258444 | 12.75 |
ENST00000261205.4
|
SYT1
|
synaptotagmin I |
| chr8_-_27115903 | 12.67 |
ENST00000350889.4
ENST00000519997.1 ENST00000519614.1 ENST00000522908.1 ENST00000265770.7 |
STMN4
|
stathmin-like 4 |
| chr1_+_169079823 | 11.41 |
ENST00000367813.3
|
ATP1B1
|
ATPase, Na+/K+ transporting, beta 1 polypeptide |
| chr6_-_152489484 | 11.12 |
ENST00000354674.4
ENST00000539504.1 |
SYNE1
|
spectrin repeat containing, nuclear envelope 1 |
| chr6_-_52705641 | 11.06 |
ENST00000370989.2
|
GSTA5
|
glutathione S-transferase alpha 5 |
| chr2_+_238768187 | 11.02 |
ENST00000254661.4
ENST00000409726.1 |
RAMP1
|
receptor (G protein-coupled) activity modifying protein 1 |
| chr17_-_66951474 | 10.74 |
ENST00000269080.2
|
ABCA8
|
ATP-binding cassette, sub-family A (ABC1), member 8 |
| chr19_+_35630628 | 10.68 |
ENST00000588715.1
ENST00000588607.1 |
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr15_-_22448819 | 10.66 |
ENST00000604066.1
|
IGHV1OR15-1
|
immunoglobulin heavy variable 1/OR15-1 (non-functional) |
| chr12_-_91572278 | 10.32 |
ENST00000425043.1
ENST00000420120.2 ENST00000441303.2 ENST00000456569.2 |
DCN
|
decorin |
| chr6_-_109330702 | 10.13 |
ENST00000356644.7
|
SESN1
|
sestrin 1 |
| chr3_-_18466026 | 10.10 |
ENST00000417717.2
|
SATB1
|
SATB homeobox 1 |
| chr22_-_50523760 | 9.90 |
ENST00000395876.2
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr15_+_80733570 | 9.77 |
ENST00000533983.1
ENST00000527771.1 ENST00000525103.1 |
ARNT2
|
aryl-hydrocarbon receptor nuclear translocator 2 |
| chr6_-_152958521 | 9.77 |
ENST00000367255.5
ENST00000265368.4 ENST00000448038.1 ENST00000341594.5 |
SYNE1
|
spectrin repeat containing, nuclear envelope 1 |
| chr11_-_6440624 | 9.72 |
ENST00000311051.3
|
APBB1
|
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| chr3_+_123813509 | 9.37 |
ENST00000460856.1
ENST00000240874.3 |
KALRN
|
kalirin, RhoGEF kinase |
| chr17_+_47865917 | 8.66 |
ENST00000259021.4
ENST00000454930.2 ENST00000509773.1 ENST00000510819.1 ENST00000424009.2 |
KAT7
|
K(lysine) acetyltransferase 7 |
| chr19_+_19144384 | 8.50 |
ENST00000392335.2
ENST00000535612.1 ENST00000537263.1 ENST00000540707.1 ENST00000541725.1 ENST00000269932.6 ENST00000546344.1 ENST00000540792.1 ENST00000536098.1 ENST00000541898.1 ENST00000543877.1 |
ARMC6
|
armadillo repeat containing 6 |
| chr2_-_179672142 | 8.50 |
ENST00000342992.6
ENST00000360870.5 ENST00000460472.2 ENST00000589042.1 ENST00000591111.1 ENST00000342175.6 ENST00000359218.5 |
TTN
|
titin |
| chr2_+_90060377 | 8.47 |
ENST00000436451.2
|
IGKV6D-21
|
immunoglobulin kappa variable 6D-21 (non-functional) |
| chr7_+_147830776 | 8.45 |
ENST00000538075.1
|
CNTNAP2
|
contactin associated protein-like 2 |
| chr9_+_71944241 | 7.94 |
ENST00000257515.8
|
FAM189A2
|
family with sequence similarity 189, member A2 |
| chrX_+_21392529 | 7.83 |
ENST00000425654.2
ENST00000543067.1 |
CNKSR2
|
connector enhancer of kinase suppressor of Ras 2 |
| chr10_-_50970322 | 7.80 |
ENST00000374103.4
|
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr19_-_19144243 | 7.66 |
ENST00000594445.1
ENST00000452918.2 ENST00000600377.1 ENST00000337018.6 |
SUGP2
|
SURP and G patch domain containing 2 |
| chr16_+_30386098 | 7.66 |
ENST00000322861.7
|
MYLPF
|
myosin light chain, phosphorylatable, fast skeletal muscle |
| chr22_-_50524298 | 7.54 |
ENST00000311597.5
|
MLC1
|
megalencephalic leukoencephalopathy with subcortical cysts 1 |
| chr20_+_1246908 | 7.31 |
ENST00000381873.3
ENST00000381867.1 |
SNPH
|
syntaphilin |
| chr11_-_71639670 | 7.30 |
ENST00000533047.1
ENST00000529844.1 |
RP11-849H4.2
|
Putative short transient receptor potential channel 2-like protein |
| chr1_-_158656488 | 7.24 |
ENST00000368147.4
|
SPTA1
|
spectrin, alpha, erythrocytic 1 (elliptocytosis 2) |
| chr2_-_136875712 | 7.08 |
ENST00000241393.3
|
CXCR4
|
chemokine (C-X-C motif) receptor 4 |
| chr2_+_1418154 | 7.01 |
ENST00000423320.1
ENST00000382198.1 |
TPO
|
thyroid peroxidase |
| chr10_-_50970382 | 6.88 |
ENST00000419399.1
ENST00000432695.1 |
OGDHL
|
oxoglutarate dehydrogenase-like |
| chr21_+_47878757 | 6.67 |
ENST00000400274.1
ENST00000427143.2 ENST00000318711.7 ENST00000457905.3 ENST00000466639.1 ENST00000435722.3 ENST00000417564.2 |
DIP2A
|
DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| chr14_-_106622419 | 6.55 |
ENST00000390604.2
|
IGHV3-16
|
immunoglobulin heavy variable 3-16 (non-functional) |
| chr5_+_140261703 | 6.48 |
ENST00000409494.1
ENST00000289272.2 |
PCDHA13
|
protocadherin alpha 13 |
| chr21_-_44299626 | 6.48 |
ENST00000330317.2
ENST00000398208.2 |
WDR4
|
WD repeat domain 4 |
| chr11_-_71639480 | 6.43 |
ENST00000529513.1
|
RP11-849H4.2
|
Putative short transient receptor potential channel 2-like protein |
| chr17_+_4855053 | 6.36 |
ENST00000518175.1
|
ENO3
|
enolase 3 (beta, muscle) |
| chr1_+_160765947 | 6.31 |
ENST00000263285.6
ENST00000368039.2 |
LY9
|
lymphocyte antigen 9 |
| chrX_+_21392553 | 6.25 |
ENST00000279451.4
|
CNKSR2
|
connector enhancer of kinase suppressor of Ras 2 |
| chr1_+_241695424 | 6.24 |
ENST00000366558.3
ENST00000366559.4 |
KMO
|
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| chr1_+_241695670 | 6.15 |
ENST00000366557.4
|
KMO
|
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| chr4_-_39033963 | 6.10 |
ENST00000381938.3
|
TMEM156
|
transmembrane protein 156 |
| chr2_-_89459813 | 6.08 |
ENST00000390256.2
|
IGKV6-21
|
immunoglobulin kappa variable 6-21 (non-functional) |
| chr4_-_149365827 | 5.95 |
ENST00000344721.4
|
NR3C2
|
nuclear receptor subfamily 3, group C, member 2 |
| chr7_+_87563557 | 5.90 |
ENST00000439864.1
ENST00000412441.1 ENST00000398201.4 ENST00000265727.7 ENST00000315984.7 ENST00000398209.3 |
ADAM22
|
ADAM metallopeptidase domain 22 |
| chr9_-_15472730 | 5.65 |
ENST00000481862.1
|
PSIP1
|
PC4 and SFRS1 interacting protein 1 |
| chr14_-_107049312 | 5.60 |
ENST00000390627.2
|
IGHV3-53
|
immunoglobulin heavy variable 3-53 |
| chr1_+_66458072 | 5.58 |
ENST00000423207.2
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr20_+_43160458 | 5.53 |
ENST00000372889.1
ENST00000372887.1 ENST00000372882.3 |
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| chr10_-_62149433 | 5.47 |
ENST00000280772.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr4_+_70861647 | 5.45 |
ENST00000246895.4
ENST00000381060.2 |
STATH
|
statherin |
| chr1_+_163038565 | 5.44 |
ENST00000421743.2
|
RGS4
|
regulator of G-protein signaling 4 |
| chr4_+_71296204 | 5.32 |
ENST00000413702.1
|
MUC7
|
mucin 7, secreted |
| chr4_-_186732048 | 5.32 |
ENST00000448662.2
ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9 |
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr1_-_207119738 | 5.26 |
ENST00000356495.4
|
PIGR
|
polymeric immunoglobulin receptor |
| chr12_-_49393092 | 5.16 |
ENST00000421952.2
|
DDN
|
dendrin |
| chr15_-_20193370 | 5.15 |
ENST00000558565.2
|
IGHV3OR15-7
|
immunoglobulin heavy variable 3/OR15-7 (pseudogene) |
| chr2_-_128568721 | 5.14 |
ENST00000322313.4
ENST00000393006.1 ENST00000409658.3 ENST00000436787.1 |
WDR33
|
WD repeat domain 33 |
| chr3_+_138067666 | 5.07 |
ENST00000475711.1
ENST00000464896.1 |
MRAS
|
muscle RAS oncogene homolog |
| chr14_-_106725723 | 5.01 |
ENST00000390609.2
|
IGHV3-23
|
immunoglobulin heavy variable 3-23 |
| chr1_-_154928562 | 4.90 |
ENST00000368463.3
ENST00000539880.1 ENST00000542459.1 ENST00000368460.3 ENST00000368465.1 |
PBXIP1
|
pre-B-cell leukemia homeobox interacting protein 1 |
| chr3_+_189349162 | 4.77 |
ENST00000264731.3
ENST00000382063.4 ENST00000418709.2 ENST00000320472.5 ENST00000392460.3 ENST00000440651.2 |
TP63
|
tumor protein p63 |
| chrX_+_22056165 | 4.73 |
ENST00000535894.1
|
PHEX
|
phosphate regulating endopeptidase homolog, X-linked |
| chr12_+_109554386 | 4.72 |
ENST00000338432.7
|
ACACB
|
acetyl-CoA carboxylase beta |
| chr2_-_196933536 | 4.69 |
ENST00000312428.6
ENST00000410072.1 |
DNAH7
|
dynein, axonemal, heavy chain 7 |
| chr19_+_35630344 | 4.67 |
ENST00000455515.2
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr2_+_238767517 | 4.65 |
ENST00000404910.2
|
RAMP1
|
receptor (G protein-coupled) activity modifying protein 1 |
| chr14_-_106518922 | 4.64 |
ENST00000390598.2
|
IGHV3-7
|
immunoglobulin heavy variable 3-7 |
| chr8_+_24151553 | 4.56 |
ENST00000265769.4
ENST00000540823.1 ENST00000397649.3 |
ADAM28
|
ADAM metallopeptidase domain 28 |
| chr5_-_41261540 | 4.55 |
ENST00000263413.3
|
C6
|
complement component 6 |
| chr5_-_32313019 | 4.55 |
ENST00000280285.5
ENST00000264934.5 |
MTMR12
|
myotubularin related protein 12 |
| chr8_+_42128812 | 4.48 |
ENST00000520810.1
ENST00000416505.2 ENST00000519735.1 ENST00000520835.1 ENST00000379708.3 |
IKBKB
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| chr5_+_180415839 | 4.33 |
ENST00000342868.6
|
BTNL3
|
butyrophilin-like 3 |
| chr10_-_90712520 | 4.15 |
ENST00000224784.6
|
ACTA2
|
actin, alpha 2, smooth muscle, aorta |
| chr12_+_69201923 | 4.10 |
ENST00000462284.1
ENST00000258149.5 ENST00000356290.4 ENST00000540827.1 ENST00000428863.2 ENST00000393412.3 |
MDM2
|
MDM2 oncogene, E3 ubiquitin protein ligase |
| chr5_-_10308125 | 3.99 |
ENST00000296658.3
|
CMBL
|
carboxymethylenebutenolidase homolog (Pseudomonas) |
| chr19_+_10541462 | 3.94 |
ENST00000293683.5
|
PDE4A
|
phosphodiesterase 4A, cAMP-specific |
| chr6_-_27835357 | 3.92 |
ENST00000331442.3
|
HIST1H1B
|
histone cluster 1, H1b |
| chr6_-_32634425 | 3.86 |
ENST00000399082.3
ENST00000399079.3 ENST00000374943.4 ENST00000434651.2 |
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1 |
| chr5_-_138775177 | 3.78 |
ENST00000302060.5
|
DNAJC18
|
DnaJ (Hsp40) homolog, subfamily C, member 18 |
| chr11_+_49050504 | 3.76 |
ENST00000332682.7
|
TRIM49B
|
tripartite motif containing 49B |
| chr1_-_60392452 | 3.76 |
ENST00000371204.3
|
CYP2J2
|
cytochrome P450, family 2, subfamily J, polypeptide 2 |
| chr19_+_57631411 | 3.75 |
ENST00000254181.4
ENST00000600940.1 |
USP29
|
ubiquitin specific peptidase 29 |
| chr1_-_156252590 | 3.74 |
ENST00000361813.5
ENST00000368267.5 |
SMG5
|
SMG5 nonsense mediated mRNA decay factor |
| chr2_-_211168332 | 3.72 |
ENST00000341685.4
|
MYL1
|
myosin, light chain 1, alkali; skeletal, fast |
| chr14_-_106845789 | 3.69 |
ENST00000390617.2
|
IGHV3-35
|
immunoglobulin heavy variable 3-35 (non-functional) |
| chr6_+_153552455 | 3.68 |
ENST00000392385.2
|
AL590867.1
|
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog |
| chr13_+_113760098 | 3.56 |
ENST00000346342.3
ENST00000541084.1 ENST00000375581.3 |
F7
|
coagulation factor VII (serum prothrombin conversion accelerator) |
| chr17_+_29664830 | 3.53 |
ENST00000444181.2
ENST00000417592.2 |
NF1
|
neurofibromin 1 |
| chr22_-_46450024 | 3.52 |
ENST00000396008.2
ENST00000333761.1 |
C22orf26
|
chromosome 22 open reading frame 26 |
| chr12_+_69864129 | 3.51 |
ENST00000547219.1
ENST00000299293.2 ENST00000549921.1 ENST00000550316.1 ENST00000548154.1 ENST00000547414.1 ENST00000550389.1 ENST00000550937.1 ENST00000549092.1 ENST00000550169.1 |
FRS2
|
fibroblast growth factor receptor substrate 2 |
| chr10_+_32856764 | 3.51 |
ENST00000375030.2
ENST00000375028.3 |
C10orf68
|
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA. |
| chrX_-_55024967 | 3.45 |
ENST00000545676.1
|
PFKFB1
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| chrX_-_33146477 | 3.41 |
ENST00000378677.2
|
DMD
|
dystrophin |
| chr12_-_111358372 | 3.37 |
ENST00000548438.1
ENST00000228841.8 |
MYL2
|
myosin, light chain 2, regulatory, cardiac, slow |
| chr10_-_75410771 | 3.34 |
ENST00000372873.4
|
SYNPO2L
|
synaptopodin 2-like |
| chr19_+_9296279 | 3.29 |
ENST00000344248.2
|
OR7D2
|
olfactory receptor, family 7, subfamily D, member 2 |
| chr2_-_89513402 | 3.28 |
ENST00000498435.1
|
IGKV1-27
|
immunoglobulin kappa variable 1-27 |
| chr7_-_116963334 | 3.27 |
ENST00000265441.3
|
WNT2
|
wingless-type MMTV integration site family member 2 |
| chr1_+_1215816 | 3.20 |
ENST00000379116.5
|
SCNN1D
|
sodium channel, non-voltage-gated 1, delta subunit |
| chr2_-_211341411 | 3.19 |
ENST00000233714.4
ENST00000443314.1 ENST00000441020.3 ENST00000450366.2 ENST00000431941.2 |
LANCL1
|
LanC lantibiotic synthetase component C-like 1 (bacterial) |
| chr14_+_68286516 | 3.16 |
ENST00000471583.1
ENST00000487270.1 ENST00000488612.1 |
RAD51B
|
RAD51 paralog B |
| chr2_-_161056802 | 3.06 |
ENST00000283249.2
ENST00000409872.1 |
ITGB6
|
integrin, beta 6 |
| chr8_-_70745575 | 3.04 |
ENST00000524945.1
|
SLCO5A1
|
solute carrier organic anion transporter family, member 5A1 |
| chr16_-_20681177 | 3.04 |
ENST00000524149.1
|
ACSM1
|
acyl-CoA synthetase medium-chain family member 1 |
| chr20_+_33814457 | 3.01 |
ENST00000246186.6
|
MMP24
|
matrix metallopeptidase 24 (membrane-inserted) |
| chr19_+_54369608 | 2.96 |
ENST00000336967.3
|
MYADM
|
myeloid-associated differentiation marker |
| chr4_-_47983519 | 2.96 |
ENST00000358519.4
ENST00000544810.1 ENST00000402813.3 |
CNGA1
|
cyclic nucleotide gated channel alpha 1 |
| chr4_+_87928413 | 2.93 |
ENST00000544085.1
|
AFF1
|
AF4/FMR2 family, member 1 |
| chr12_+_10460417 | 2.89 |
ENST00000381908.3
ENST00000336164.4 ENST00000350274.5 |
KLRD1
|
killer cell lectin-like receptor subfamily D, member 1 |
| chr8_+_55370487 | 2.87 |
ENST00000297316.4
|
SOX17
|
SRY (sex determining region Y)-box 17 |
| chr19_+_52074502 | 2.87 |
ENST00000545217.1
ENST00000262259.2 ENST00000596504.1 |
ZNF175
|
zinc finger protein 175 |
| chr3_+_101546827 | 2.84 |
ENST00000461724.1
ENST00000483180.1 ENST00000394054.2 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr4_+_96012614 | 2.83 |
ENST00000264568.4
|
BMPR1B
|
bone morphogenetic protein receptor, type IB |
| chr19_-_3786354 | 2.80 |
ENST00000395040.2
ENST00000310132.6 |
MATK
|
megakaryocyte-associated tyrosine kinase |
| chr17_+_44588877 | 2.72 |
ENST00000576629.1
|
LRRC37A2
|
leucine rich repeat containing 37, member A2 |
| chr1_+_16010779 | 2.72 |
ENST00000375799.3
ENST00000375793.2 |
PLEKHM2
|
pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| chr16_+_33006369 | 2.70 |
ENST00000425181.3
|
IGHV3OR16-10
|
immunoglobulin heavy variable 3/OR16-10 (non-functional) |
| chr11_-_59633951 | 2.70 |
ENST00000257264.3
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family) |
| chr11_+_60223312 | 2.66 |
ENST00000532491.1
ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr11_+_62009653 | 2.65 |
ENST00000244926.3
|
SCGB1D2
|
secretoglobin, family 1D, member 2 |
| chr1_-_79472365 | 2.64 |
ENST00000370742.3
|
ELTD1
|
EGF, latrophilin and seven transmembrane domain containing 1 |
| chr4_+_41614909 | 2.64 |
ENST00000509454.1
ENST00000396595.3 ENST00000381753.4 |
LIMCH1
|
LIM and calponin homology domains 1 |
| chr2_+_38893047 | 2.61 |
ENST00000272252.5
|
GALM
|
galactose mutarotase (aldose 1-epimerase) |
| chr13_+_49280951 | 2.61 |
ENST00000282018.3
|
CYSLTR2
|
cysteinyl leukotriene receptor 2 |
| chr6_+_122720681 | 2.58 |
ENST00000368455.4
ENST00000452194.1 |
HSF2
|
heat shock transcription factor 2 |
| chr1_+_171283331 | 2.48 |
ENST00000367749.3
|
FMO4
|
flavin containing monooxygenase 4 |
| chr11_+_55029628 | 2.41 |
ENST00000417545.2
|
TRIM48
|
tripartite motif containing 48 |
| chr19_-_3786253 | 2.38 |
ENST00000585778.1
|
MATK
|
megakaryocyte-associated tyrosine kinase |
| chr10_-_735553 | 2.37 |
ENST00000280886.6
ENST00000423550.1 |
DIP2C
|
DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| chr11_+_60223225 | 2.27 |
ENST00000524807.1
ENST00000345732.4 |
MS4A1
|
membrane-spanning 4-domains, subfamily A, member 1 |
| chr7_+_152456829 | 2.27 |
ENST00000377776.3
ENST00000256001.8 ENST00000397282.2 |
ACTR3B
|
ARP3 actin-related protein 3 homolog B (yeast) |
| chr1_+_32716840 | 2.27 |
ENST00000336890.5
|
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chrX_+_37639264 | 2.26 |
ENST00000378588.4
|
CYBB
|
cytochrome b-245, beta polypeptide |
| chr1_+_164528866 | 2.23 |
ENST00000420696.2
|
PBX1
|
pre-B-cell leukemia homeobox 1 |
| chr4_-_186317034 | 2.21 |
ENST00000505916.1
|
LRP2BP
|
LRP2 binding protein |
| chr2_-_161056762 | 2.16 |
ENST00000428609.2
ENST00000409967.2 |
ITGB6
|
integrin, beta 6 |
| chr1_-_175162048 | 2.14 |
ENST00000444639.1
|
KIAA0040
|
KIAA0040 |
| chr11_-_79151695 | 2.13 |
ENST00000278550.7
|
TENM4
|
teneurin transmembrane protein 4 |
| chr8_+_24151620 | 2.12 |
ENST00000437154.2
|
ADAM28
|
ADAM metallopeptidase domain 28 |
| chr6_+_25754927 | 2.11 |
ENST00000377905.4
ENST00000439485.2 |
SLC17A4
|
solute carrier family 17, member 4 |
| chr2_+_157330081 | 2.10 |
ENST00000409674.1
|
GPD2
|
glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| chr17_+_38219063 | 2.09 |
ENST00000584985.1
ENST00000264637.4 ENST00000450525.2 |
THRA
|
thyroid hormone receptor, alpha |
| chr3_+_123813543 | 2.05 |
ENST00000360013.3
|
KALRN
|
kalirin, RhoGEF kinase |
| chr1_+_32716857 | 2.01 |
ENST00000482949.1
ENST00000495610.2 |
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr9_-_104145795 | 1.99 |
ENST00000259407.2
|
BAAT
|
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) |
| chr12_+_32260085 | 1.98 |
ENST00000548411.1
ENST00000281474.5 ENST00000551086.1 |
BICD1
|
bicaudal D homolog 1 (Drosophila) |
| chr11_-_10590118 | 1.98 |
ENST00000529598.1
|
LYVE1
|
lymphatic vessel endothelial hyaluronan receptor 1 |
| chr13_-_46679144 | 1.80 |
ENST00000181383.4
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr21_-_27423339 | 1.79 |
ENST00000415997.1
|
APP
|
amyloid beta (A4) precursor protein |
| chrX_+_37639302 | 1.79 |
ENST00000545017.1
ENST00000536160.1 |
CYBB
|
cytochrome b-245, beta polypeptide |
| chr10_+_5005445 | 1.73 |
ENST00000380872.4
|
AKR1C1
|
aldo-keto reductase family 1, member C1 |
| chr3_-_164875850 | 1.71 |
ENST00000472120.1
|
RP11-747D18.1
|
RP11-747D18.1 |
| chr19_+_17862274 | 1.68 |
ENST00000596536.1
ENST00000593870.1 ENST00000598086.1 ENST00000598932.1 ENST00000595023.1 ENST00000594068.1 ENST00000596507.1 ENST00000595033.1 ENST00000597718.1 |
FCHO1
|
FCH domain only 1 |
| chr19_-_41256207 | 1.68 |
ENST00000598485.2
ENST00000470681.1 ENST00000339153.3 ENST00000598729.1 |
C19orf54
|
chromosome 19 open reading frame 54 |
| chr4_-_110723335 | 1.68 |
ENST00000394634.2
|
CFI
|
complement factor I |
| chr13_-_46679185 | 1.66 |
ENST00000439329.3
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr13_-_99910673 | 1.63 |
ENST00000397473.2
ENST00000397470.2 |
GPR18
|
G protein-coupled receptor 18 |
| chr14_+_78870030 | 1.63 |
ENST00000553631.1
ENST00000554719.1 |
NRXN3
|
neurexin 3 |
| chr13_+_24553933 | 1.62 |
ENST00000424834.2
ENST00000439928.2 |
SPATA13
RP11-309I15.1
|
spermatogenesis associated 13 RP11-309I15.1 |
| chr4_+_71588372 | 1.62 |
ENST00000536664.1
|
RUFY3
|
RUN and FYVE domain containing 3 |
| chr10_+_123923205 | 1.59 |
ENST00000369004.3
ENST00000260733.3 |
TACC2
|
transforming, acidic coiled-coil containing protein 2 |
| chr1_+_160051319 | 1.57 |
ENST00000368088.3
|
KCNJ9
|
potassium inwardly-rectifying channel, subfamily J, member 9 |
| chr5_-_150603679 | 1.56 |
ENST00000355417.2
|
CCDC69
|
coiled-coil domain containing 69 |
| chr1_+_244214577 | 1.54 |
ENST00000358704.4
|
ZBTB18
|
zinc finger and BTB domain containing 18 |
| chr17_+_32582293 | 1.46 |
ENST00000580907.1
ENST00000225831.4 |
CCL2
|
chemokine (C-C motif) ligand 2 |
| chr4_+_120056939 | 1.45 |
ENST00000307128.5
|
MYOZ2
|
myozenin 2 |
| chr5_+_53751445 | 1.44 |
ENST00000302005.1
|
HSPB3
|
heat shock 27kDa protein 3 |
| chr4_+_55095264 | 1.41 |
ENST00000257290.5
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide |
| chr12_+_86268065 | 1.41 |
ENST00000551529.1
ENST00000256010.6 |
NTS
|
neurotensin |
| chr12_+_10460549 | 1.39 |
ENST00000543420.1
ENST00000543777.1 |
KLRD1
|
killer cell lectin-like receptor subfamily D, member 1 |
| chr6_-_42690312 | 1.38 |
ENST00000230381.5
|
PRPH2
|
peripherin 2 (retinal degeneration, slow) |
| chr4_-_110723194 | 1.36 |
ENST00000394635.3
|
CFI
|
complement factor I |
| chr19_-_51466681 | 1.34 |
ENST00000456750.2
|
KLK6
|
kallikrein-related peptidase 6 |
| chr8_+_50824233 | 1.31 |
ENST00000522124.1
|
SNTG1
|
syntrophin, gamma 1 |
| chr4_+_40337340 | 1.26 |
ENST00000310169.2
|
CHRNA9
|
cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| chr9_-_33402506 | 1.26 |
ENST00000377425.4
ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1 |
AQP7
|
aquaporin 7 |
| chr2_-_235405679 | 1.24 |
ENST00000390645.2
|
ARL4C
|
ADP-ribosylation factor-like 4C |
| chr4_-_110723134 | 1.24 |
ENST00000510800.1
ENST00000512148.1 |
CFI
|
complement factor I |
| chr4_-_155511887 | 1.23 |
ENST00000302053.3
ENST00000403106.3 |
FGA
|
fibrinogen alpha chain |
| chr11_-_63376013 | 1.19 |
ENST00000540943.1
|
PLA2G16
|
phospholipase A2, group XVI |
| chr15_+_100106126 | 1.18 |
ENST00000558812.1
ENST00000338042.6 |
MEF2A
|
myocyte enhancer factor 2A |
| chr1_-_151798546 | 1.18 |
ENST00000356728.6
|
RORC
|
RAR-related orphan receptor C |
| chrX_-_15402498 | 1.15 |
ENST00000297904.3
|
FIGF
|
c-fos induced growth factor (vascular endothelial growth factor D) |
| chr11_-_102595681 | 1.10 |
ENST00000236826.3
|
MMP8
|
matrix metallopeptidase 8 (neutrophil collagenase) |
| chr2_-_233641265 | 1.07 |
ENST00000438786.1
ENST00000409779.1 ENST00000233826.3 |
KCNJ13
|
potassium inwardly-rectifying channel, subfamily J, member 13 |
| chr11_-_10590238 | 1.04 |
ENST00000256178.3
|
LYVE1
|
lymphatic vessel endothelial hyaluronan receptor 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TEAD4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.8 | 26.3 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 4.9 | 29.4 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 3.2 | 9.7 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 2.9 | 34.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 2.9 | 11.4 | GO:1903276 | regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278) |
| 2.8 | 8.5 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 2.8 | 8.4 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 2.5 | 12.4 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 2.3 | 11.4 | GO:0060125 | negative regulation of growth hormone secretion(GO:0060125) |
| 2.2 | 8.7 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 2.1 | 20.9 | GO:0090292 | nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 1.7 | 15.7 | GO:0097647 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 1.4 | 5.5 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 1.4 | 4.1 | GO:0071301 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 1.3 | 10.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 1.2 | 4.8 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 1.2 | 3.6 | GO:0097068 | response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386) |
| 1.2 | 4.7 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 1.2 | 3.5 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 1.2 | 3.5 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 1.2 | 17.4 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 1.1 | 4.5 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 1.1 | 4.5 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 1.1 | 5.3 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 1.0 | 3.0 | GO:0018874 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 1.0 | 7.1 | GO:0044800 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 1.0 | 2.9 | GO:0060214 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) endocardium formation(GO:0060214) gall bladder development(GO:0061010) |
| 0.9 | 4.7 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.9 | 9.0 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 0.9 | 2.6 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.9 | 3.5 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 0.8 | 4.0 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.7 | 3.0 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.7 | 11.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.7 | 2.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) |
| 0.7 | 1.4 | GO:0038091 | VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) |
| 0.7 | 2.1 | GO:0045925 | female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925) |
| 0.7 | 4.1 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.7 | 3.5 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.7 | 3.3 | GO:1904954 | canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954) |
| 0.6 | 5.7 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.6 | 13.0 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.6 | 2.8 | GO:0048165 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.5 | 2.7 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.5 | 3.2 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.5 | 7.3 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.5 | 5.2 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 0.5 | 15.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.5 | 5.5 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.5 | 1.5 | GO:1901624 | negative regulation of lymphocyte chemotaxis(GO:1901624) |
| 0.5 | 20.5 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.5 | 5.6 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.4 | 18.3 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.4 | 2.6 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
| 0.4 | 3.9 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.4 | 4.7 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.4 | 3.4 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.4 | 2.1 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.4 | 28.8 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.4 | 2.0 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.4 | 14.7 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.4 | 1.8 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) cellular response to norepinephrine stimulus(GO:0071874) |
| 0.3 | 5.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.3 | 6.3 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
| 0.3 | 16.4 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.3 | 1.0 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.3 | 3.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.3 | 2.7 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.3 | 1.2 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) |
| 0.3 | 8.6 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.3 | 23.6 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.3 | 1.3 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.2 | 1.7 | GO:0071395 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.2 | 2.0 | GO:0019530 | taurine metabolic process(GO:0019530) |
| 0.2 | 3.8 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.2 | 1.3 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.2 | 1.0 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.2 | 5.9 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.2 | 7.2 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.2 | 2.7 | GO:0044331 | cell-cell adhesion mediated by cadherin(GO:0044331) |
| 0.2 | 2.5 | GO:0042737 | drug catabolic process(GO:0042737) |
| 0.2 | 1.2 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.2 | 5.3 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 0.6 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.2 | 17.3 | GO:0002455 | humoral immune response mediated by circulating immunoglobulin(GO:0002455) |
| 0.2 | 5.1 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.1 | 6.4 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.1 | 5.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 11.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.1 | 0.4 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 3.9 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 1.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 1.2 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
| 0.1 | 1.4 | GO:0050880 | regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880) |
| 0.1 | 0.9 | GO:0030578 | PML body organization(GO:0030578) |
| 0.1 | 3.0 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.1 | 13.8 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.1 | 6.5 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.1 | 5.3 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.1 | 1.6 | GO:0051255 | spindle midzone assembly(GO:0051255) |
| 0.1 | 1.6 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 0.9 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 13.7 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 4.5 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 3.0 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.1 | 0.9 | GO:1902172 | keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) |
| 0.1 | 1.3 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 2.2 | GO:0006954 | inflammatory response(GO:0006954) |
| 0.1 | 3.7 | GO:0032210 | regulation of telomere maintenance via telomerase(GO:0032210) |
| 0.1 | 3.2 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.1 | 5.2 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.1 | 4.9 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.1 | 4.3 | GO:0002228 | natural killer cell mediated immunity(GO:0002228) |
| 0.1 | 2.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.6 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.1 | 0.5 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.1 | 2.3 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 1.6 | GO:0021987 | cerebral cortex development(GO:0021987) |
| 0.0 | 3.3 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 0.0 | 1.5 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 5.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 1.2 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.4 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.0 | 1.4 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 6.0 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.0 | 3.0 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
| 0.0 | 0.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.7 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
| 0.0 | 0.8 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.9 | GO:0051058 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 2.9 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.0 | 1.4 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
| 0.0 | 0.0 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 26.3 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 2.5 | 34.7 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 2.2 | 15.7 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 2.1 | 14.7 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 2.0 | 40.8 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.8 | 5.3 | GO:0097679 | other organism cytoplasm(GO:0097679) |
| 1.7 | 5.2 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 1.6 | 20.9 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 1.4 | 10.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 1.3 | 6.5 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 1.3 | 11.5 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 1.2 | 14.0 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 1.1 | 6.4 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.0 | 4.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 1.0 | 7.2 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.7 | 8.4 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.7 | 33.8 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.7 | 2.0 | GO:0033647 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.6 | 13.9 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.5 | 3.2 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.5 | 4.7 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.5 | 4.5 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.5 | 16.7 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.4 | 5.1 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.3 | 2.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.3 | 4.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.3 | 5.4 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.3 | 4.7 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.3 | 16.4 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 3.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.3 | 4.4 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 4.0 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.2 | 5.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 3.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.2 | 2.8 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.2 | 5.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.2 | 4.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 5.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 3.0 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 3.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 16.8 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 28.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 1.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 2.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 3.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 15.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 7.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 21.0 | GO:0099572 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 10.0 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 3.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 1.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 4.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 1.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 3.5 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 12.1 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 5.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 3.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 7.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 3.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 34.0 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 3.2 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 6.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 3.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 4.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.5 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 4.1 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 1.2 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 2.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 7.3 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 2.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 4.0 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 6.8 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 3.8 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 2.7 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 1.7 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 1.6 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 3.5 | GO:0044445 | cytosolic part(GO:0044445) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 26.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 3.9 | 15.7 | GO:0031716 | calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716) |
| 2.9 | 14.7 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 2.0 | 10.1 | GO:0070728 | leucine binding(GO:0070728) |
| 1.8 | 5.5 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 1.5 | 13.9 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 1.4 | 4.1 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 1.2 | 4.7 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 1.2 | 7.0 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 1.1 | 9.0 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 1.1 | 4.5 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 1.1 | 6.4 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.0 | 10.0 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.9 | 4.3 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.8 | 12.4 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.8 | 17.3 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.7 | 20.9 | GO:0005521 | lamin binding(GO:0005521) |
| 0.7 | 11.4 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.7 | 9.8 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.7 | 3.5 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.7 | 5.3 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.6 | 7.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.6 | 3.2 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.6 | 33.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.5 | 13.0 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.5 | 6.5 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.5 | 2.1 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.5 | 2.6 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 0.5 | 9.7 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.5 | 26.0 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.5 | 8.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.5 | 2.0 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.5 | 1.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.5 | 5.7 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.5 | 1.4 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 0.5 | 34.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.4 | 1.7 | GO:0047023 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718) |
| 0.4 | 4.8 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.3 | 3.0 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.3 | 3.0 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.3 | 2.6 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.3 | 3.5 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.3 | 1.3 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.3 | 2.8 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.3 | 4.0 | GO:0050664 | superoxide-generating NADPH oxidase activity(GO:0016175) oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664) |
| 0.3 | 3.2 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.3 | 5.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.3 | 2.5 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.3 | 4.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) dynein intermediate chain binding(GO:0045505) |
| 0.3 | 3.9 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.3 | 3.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.3 | 2.1 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.3 | 9.5 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.3 | 6.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 2.7 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.2 | 1.2 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.2 | 3.2 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.2 | 3.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 11.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 2.6 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.2 | 4.9 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.2 | 3.4 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.2 | 3.8 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.2 | 5.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 1.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 27.0 | GO:0003823 | antigen binding(GO:0003823) |
| 0.2 | 2.0 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.2 | 1.8 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.2 | 5.9 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.2 | 1.2 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.2 | 3.3 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 3.7 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 1.7 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 17.4 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 0.7 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.1 | 15.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.1 | 5.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 3.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 8.2 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 3.0 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 2.6 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 6.1 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.4 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.1 | 10.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 21.6 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.1 | 7.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 5.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 2.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 6.0 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.1 | 1.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
| 0.0 | 9.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 4.5 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 1.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 3.7 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 3.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 1.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 2.0 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.4 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.9 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 1.6 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
| 0.0 | 6.2 | GO:0005198 | structural molecule activity(GO:0005198) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 33.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.5 | 26.3 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.5 | 11.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.3 | 8.8 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.3 | 3.4 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.3 | 14.0 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.3 | 4.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.3 | 8.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.2 | 23.8 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.2 | 5.2 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 6.7 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 10.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 3.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 4.0 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.1 | 3.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.4 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 7.5 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 1.5 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.1 | 6.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.4 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.1 | 3.0 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 5.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 1.1 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 7.7 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.1 | 5.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 4.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 2.1 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 1.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 2.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 4.1 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 3.5 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.6 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 3.7 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 2.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 11.7 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 8.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 4.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 5.3 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 1.4 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 26.3 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 1.4 | 7.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 1.3 | 34.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.9 | 12.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.7 | 5.7 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.4 | 18.3 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.4 | 4.5 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.4 | 12.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.3 | 11.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.3 | 11.4 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.3 | 7.0 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.3 | 10.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 5.3 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.3 | 30.2 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 2.0 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.2 | 4.1 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 3.6 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.2 | 20.9 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 3.0 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 3.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.2 | 9.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 1.8 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 8.8 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 18.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 5.4 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.2 | 4.7 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 2.6 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.1 | 3.5 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.1 | 10.1 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 8.1 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.8 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 5.6 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 4.1 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.1 | 9.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 4.0 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 1.3 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 1.6 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 1.2 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 1.3 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.1 | 2.8 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 3.3 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 4.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.1 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 3.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 2.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 5.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 5.2 | REACTOME SIGNALING BY ERBB2 | Genes involved in Signaling by ERBB2 |
| 0.0 | 1.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 1.5 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 1.2 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 2.9 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 3.7 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 2.1 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.0 | 0.7 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 0.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |