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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)

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Results for TGIF1

Z-value: 1.03

Motif logo

Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.16 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3451646_3451722-0.698.8e-32Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_54318566 36.21 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr18_+_54318616 32.49 ENST00000254442.3
WD repeat domain 7
chr11_-_111781454 32.47 ENST00000533280.1
crystallin, alpha B
chr11_-_111781610 31.98 ENST00000525823.1
crystallin, alpha B
chr11_-_111781554 28.83 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr6_-_84418841 27.90 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr6_-_84418860 27.70 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr14_-_21493123 26.80 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG family member 2
chr11_-_111794446 26.72 ENST00000527950.1
crystallin, alpha B
chr4_+_166300084 23.56 ENST00000402744.4
carboxypeptidase E
chr1_-_149889382 22.66 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr14_+_100150622 22.59 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr19_-_47164386 22.03 ENST00000391916.2
ENST00000410105.2
dishevelled-binding antagonist of beta-catenin 3
chr2_-_71454185 19.98 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr7_+_26438187 19.71 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr14_-_21492113 19.55 ENST00000554094.1
NDRG family member 2
chr20_+_1246908 19.31 ENST00000381873.3
ENST00000381867.1
syntaphilin
chrX_-_13835147 19.29 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr12_+_113229452 18.49 ENST00000389385.4
rabphilin 3A homolog (mouse)
chr7_+_95401877 18.08 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr19_-_36643329 17.70 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr12_+_113229543 17.59 ENST00000447659.2
rabphilin 3A homolog (mouse)
chr7_+_95401851 17.48 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chr5_-_132112907 17.24 ENST00000458488.2
septin 8
chr5_-_132112921 16.89 ENST00000378721.4
ENST00000378701.1
septin 8
chr4_+_88896819 16.84 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr22_-_50524298 16.76 ENST00000311597.5
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523760 16.43 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr15_-_48937884 16.36 ENST00000560355.1
fibrillin 1
chr14_-_21492251 16.08 ENST00000554398.1
NDRG family member 2
chrX_-_13835461 15.82 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr10_+_86004802 15.78 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
retinal G protein coupled receptor
chr17_+_57232690 15.74 ENST00000262293.4
proline rich 11
chr19_+_45409011 15.48 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr5_+_173472607 15.33 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr10_-_99393242 15.07 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chrX_+_129473859 14.66 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_11907829 14.63 ENST00000376480.3
natriuretic peptide A
chr19_-_45826125 14.62 ENST00000221476.3
creatine kinase, muscle
chr2_-_152589670 14.25 ENST00000604864.1
ENST00000603639.1
nebulin
chr10_-_124768300 13.97 ENST00000368886.5
IKAROS family zinc finger 5 (Pegasus)
chr14_+_100842735 13.81 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
WD repeat domain 25
chr10_-_99393208 13.80 ENST00000307450.6
MORN repeat containing 4
chr4_+_128886424 13.76 ENST00000398965.1
chromosome 4 open reading frame 29
chr3_-_128879875 13.62 ENST00000418265.1
ENST00000393292.3
ENST00000273541.8
ISY1-RAB43 readthrough
ISY1 splicing factor homolog (S. cerevisiae)
chr3_-_127541194 13.53 ENST00000453507.2
monoglyceride lipase
chr12_+_101988627 13.29 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chrX_+_101380642 13.09 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr14_+_22984601 12.80 ENST00000390509.1
T cell receptor alpha joining 28
chr5_+_134240588 12.78 ENST00000254908.6
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr7_-_137028534 12.55 ENST00000348225.2
pleiotrophin
chr1_+_163038565 12.36 ENST00000421743.2
regulator of G-protein signaling 4
chrX_+_110187513 12.36 ENST00000446737.1
ENST00000425146.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr14_+_23299088 12.23 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
mitochondrial ribosomal protein L52
chr7_+_97361218 12.11 ENST00000319273.5
tachykinin, precursor 1
chr7_-_137028498 11.90 ENST00000393083.2
pleiotrophin
chr2_+_166152283 11.89 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_127541679 11.79 ENST00000265052.5
monoglyceride lipase
chr12_-_54978086 11.73 ENST00000553113.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr2_+_242127924 11.67 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chrX_+_16737718 11.50 ENST00000380155.3
synapse associated protein 1
chr16_+_30710462 11.46 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
Snf2-related CREBBP activator protein
chr4_+_128886532 11.25 ENST00000444616.1
ENST00000388795.5
chromosome 4 open reading frame 29
chr10_-_73848764 11.24 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_140868717 11.21 ENST00000252087.1
protocadherin gamma subfamily C, 5
chr3_+_35722487 11.07 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr16_+_50775948 11.07 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
cylindromatosis (turban tumor syndrome)
chr17_-_66951474 10.88 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_+_108908962 10.87 ENST00000552695.1
ENST00000552758.1
ENST00000361549.2
FIC domain containing
chr20_+_4667094 10.86 ENST00000424424.1
ENST00000457586.1
prion protein
chr11_+_12132117 10.81 ENST00000256194.4
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr3_+_45067659 10.79 ENST00000296130.4
C-type lectin domain family 3, member B
chr7_+_97361388 10.64 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr11_+_71927807 10.55 ENST00000298223.6
ENST00000454954.2
ENST00000541003.1
ENST00000539412.1
ENST00000536778.1
ENST00000535625.1
ENST00000321324.7
folate receptor 2 (fetal)
chr12_+_101988774 10.44 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr16_-_30582888 10.26 ENST00000563707.1
ENST00000567855.1
zinc finger protein 688
chr5_+_157170703 10.15 ENST00000286307.5
LSM11, U7 small nuclear RNA associated
chr3_-_127542051 10.11 ENST00000398104.1
monoglyceride lipase
chr12_-_112819896 10.07 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr3_+_4535155 9.88 ENST00000544951.1
inositol 1,4,5-trisphosphate receptor, type 1
chr7_+_30951461 9.66 ENST00000311813.4
aquaporin 1 (Colton blood group)
chr9_-_79307096 9.65 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
prune homolog 2 (Drosophila)
chr8_+_38243821 9.59 ENST00000519476.2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_+_173686303 9.48 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr1_-_150669604 9.42 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr15_+_42841008 9.09 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS augmin-like complex, subunit 2
chr17_-_26220366 9.03 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYR motif containing 9
Uncharacterized protein
chr8_-_20161466 9.00 ENST00000381569.1
leucine zipper, putative tumor suppressor 1
chr6_+_83777374 8.90 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr3_-_122512619 8.81 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr3_-_47622282 8.75 ENST00000383738.2
ENST00000264723.4
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr19_-_14228541 8.43 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr18_+_32556892 8.39 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
microtubule-associated protein, RP/EB family, member 2
chr19_-_55686399 8.34 ENST00000587067.1
synaptotagmin V
chr19_-_10121144 8.31 ENST00000264828.3
collagen, type V, alpha 3
chr20_-_9819674 8.25 ENST00000378429.3
p21 protein (Cdc42/Rac)-activated kinase 7
chr16_+_2588012 8.17 ENST00000354836.5
ENST00000389224.3
3-phosphoinositide dependent protein kinase-1
chr10_-_90751038 8.08 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr10_-_73848531 7.91 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr9_+_17135016 7.88 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr6_-_3227877 7.87 ENST00000259818.7
tubulin, beta 2B class IIb
chr22_+_17082732 7.78 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr3_-_127542021 7.72 ENST00000434178.2
monoglyceride lipase
chr4_+_77870960 7.69 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
septin 11
chr21_-_35987438 7.68 ENST00000313806.4
regulator of calcineurin 1
chr19_-_38714847 7.53 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr6_-_13487784 7.51 ENST00000379287.3
glucose-fructose oxidoreductase domain containing 1
chr1_+_2036149 7.41 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
protein kinase C, zeta
chr22_-_36013368 7.41 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr2_+_97202480 7.36 ENST00000357485.3
AT rich interactive domain 5A (MRF1-like)
chr9_-_35812236 7.29 ENST00000340291.2
sperm associated antigen 8
chr18_-_52969844 7.26 ENST00000561831.3
transcription factor 4
chr8_-_57358432 7.23 ENST00000517415.1
ENST00000314922.3
proenkephalin
chr2_+_24714729 7.21 ENST00000406961.1
ENST00000405141.1
nuclear receptor coactivator 1
chr2_-_201936302 7.18 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr3_-_142166904 7.15 ENST00000264951.4
5'-3' exoribonuclease 1
chr9_+_17134980 7.14 ENST00000380647.3
centlein, centrosomal protein
chr19_+_58111241 7.14 ENST00000597700.1
ENST00000332854.6
ENST00000597864.1
zinc finger protein 530
chr8_+_42552533 7.09 ENST00000289957.2
cholinergic receptor, nicotinic, beta 3 (neuronal)
chr1_+_205473720 7.07 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr1_-_54872059 7.02 ENST00000371320.3
single stranded DNA binding protein 3
chr11_-_84028180 6.87 ENST00000280241.8
discs, large homolog 2 (Drosophila)
chr16_+_2198604 6.74 ENST00000210187.6
RAB26, member RAS oncogene family
chrX_-_99987088 6.71 ENST00000372981.1
ENST00000263033.5
synaptotagmin-like 4
chr4_-_46391367 6.70 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr5_-_131329918 6.58 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
acyl-CoA synthetase long-chain family member 6
chr1_-_156252590 6.57 ENST00000361813.5
ENST00000368267.5
SMG5 nonsense mediated mRNA decay factor
chr10_-_48438974 6.55 ENST00000224605.2
growth differentiation factor 10
chr15_-_42840961 6.53 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
leucine rich repeat containing 57
chr19_+_7953384 6.49 ENST00000306708.6
leucine rich repeat containing 8 family, member E
chr18_-_52989525 6.46 ENST00000457482.3
transcription factor 4
chr13_+_28494130 6.45 ENST00000381033.4
pancreatic and duodenal homeobox 1
chr11_+_89867803 6.44 ENST00000321955.4
ENST00000525171.1
ENST00000375944.3
N-acetylated alpha-linked acidic dipeptidase 2
chr20_+_2276639 6.43 ENST00000381458.5
transglutaminase 3
chr3_-_101232019 6.40 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr4_-_89205879 6.31 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr16_+_50775971 6.27 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
cylindromatosis (turban tumor syndrome)
chr1_+_172628154 6.24 ENST00000340030.3
ENST00000367721.2
Fas ligand (TNF superfamily, member 6)
chr2_-_145275228 6.09 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
zinc finger E-box binding homeobox 2
chr1_+_22379179 6.08 ENST00000315554.8
ENST00000421089.2
cell division cycle 42
chr14_+_21785693 6.05 ENST00000382933.4
ENST00000557351.1
retinitis pigmentosa GTPase regulator interacting protein 1
chr19_+_19030497 5.94 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr3_-_183273477 5.90 ENST00000341319.3
kelch-like family member 6
chr10_+_1102721 5.82 ENST00000263150.4
WD repeat domain 37
chr22_+_50946645 5.82 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
non-SMC condensin II complex, subunit H2
chrX_-_48931648 5.79 ENST00000376386.3
ENST00000376390.4
PRA1 domain family, member 2
chr11_-_6426635 5.78 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_-_30134524 5.71 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
mitogen-activated protein kinase 3
chr5_-_131330272 5.69 ENST00000379240.1
acyl-CoA synthetase long-chain family member 6
chr3_+_169491171 5.63 ENST00000356716.4
myoneurin
chr8_+_145743360 5.62 ENST00000527730.1
ENST00000529022.1
ENST00000292524.1
leucine rich repeat containing 14
chr16_-_57219966 5.54 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
family with sequence similarity 192, member A
chr19_-_40791211 5.53 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr1_-_151119087 5.46 ENST00000341697.3
ENST00000368914.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr8_-_41522779 5.45 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chr17_+_68165657 5.38 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr2_+_33661382 5.36 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_-_99540328 5.27 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr16_-_53537105 5.27 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKT interacting protein
chr3_+_4535025 5.26 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
inositol 1,4,5-trisphosphate receptor, type 1
chr6_+_41021027 5.26 ENST00000244669.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr11_+_111848024 5.26 ENST00000315253.5
DIX domain containing 1
chr6_+_31105426 5.14 ENST00000547221.1
psoriasis susceptibility 1 candidate 1
chr20_-_45142154 5.11 ENST00000347606.4
ENST00000457685.2
zinc finger protein 334
chr6_+_73076432 5.10 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr3_-_18466026 5.04 ENST00000417717.2
SATB homeobox 1
chr20_-_9819479 5.04 ENST00000378423.1
ENST00000353224.5
p21 protein (Cdc42/Rac)-activated kinase 7
chrX_+_153775821 5.01 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr10_+_124768482 4.97 ENST00000368869.4
ENST00000358776.4
acyl-CoA dehydrogenase, short/branched chain
chr5_-_19988339 4.97 ENST00000382275.1
cadherin 18, type 2
chr17_+_64298944 4.96 ENST00000413366.3
protein kinase C, alpha
chr1_-_16344500 4.95 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
heat shock 27kDa protein family, member 7 (cardiovascular)
chr2_+_118846008 4.92 ENST00000245787.4
insulin induced gene 2
chr12_-_121342170 4.88 ENST00000353487.2
signal peptide peptidase like 3
chr19_+_41903709 4.86 ENST00000542943.1
ENST00000457836.2
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr5_-_132113036 4.78 ENST00000378706.1
septin 8
chr4_-_46391805 4.78 ENST00000540012.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr16_+_2587998 4.75 ENST00000441549.3
ENST00000268673.7
3-phosphoinositide dependent protein kinase-1
chr18_-_21891460 4.73 ENST00000357041.4
oxysterol binding protein-like 1A
chr6_+_17600576 4.73 ENST00000259963.3
family with sequence similarity 8, member A1
chr11_+_27076764 4.69 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_134615443 4.64 ENST00000372195.1
Rap guanine nucleotide exchange factor (GEF) 1
chr11_+_46316677 4.60 ENST00000534787.1
cAMP responsive element binding protein 3-like 1
chr17_+_42923686 4.59 ENST00000591513.1
HIG1 hypoxia inducible domain family, member 1B
chr8_-_8318847 4.58 ENST00000521218.1
CTA-398F10.2
chr16_+_71392616 4.57 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
calbindin 2
chr5_+_133984462 4.57 ENST00000398844.2
ENST00000322887.4
SEC24 family member A
chr11_-_31832581 4.55 ENST00000379111.2
paired box 6
chr11_-_118436606 4.54 ENST00000530872.1
intraflagellar transport 46 homolog (Chlamydomonas)
chr6_-_41863098 4.52 ENST00000373006.1
ubiquitin specific peptidase 49
chr6_+_32407619 4.52 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr4_+_95972822 4.47 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr15_-_48937982 4.44 ENST00000316623.5
fibrillin 1
chr5_-_139283982 4.32 ENST00000340391.3
neuregulin 2
chrX_+_47696275 4.31 ENST00000376954.1
ENST00000338637.7
zinc finger protein 81
chr1_+_245318279 4.27 ENST00000407071.2
kinesin family member 26B
chr1_+_156124162 4.22 ENST00000368282.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_+_94929110 4.18 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr4_-_89205705 4.07 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr8_+_134203303 4.05 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WNT1 inducible signaling pathway protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 25.0 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
8.2 24.5 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
7.7 15.5 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
6.7 120.0 GO:0007021 tubulin complex assembly(GO:0007021)
6.2 43.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
6.1 18.3 GO:1990108 protein linear deubiquitination(GO:1990108)
5.6 16.8 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
5.0 14.9 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
4.7 23.6 GO:0030070 insulin processing(GO:0030070)
4.2 20.8 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
4.1 12.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
4.1 16.3 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
3.9 61.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.7 14.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
3.6 10.8 GO:0019417 sulfur oxidation(GO:0019417)
3.6 14.2 GO:0007525 somatic muscle development(GO:0007525)
3.5 35.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
3.4 13.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
3.2 35.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
3.2 9.7 GO:0072019 carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
3.0 15.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
3.0 11.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
2.5 22.7 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
2.5 22.6 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.4 7.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.4 7.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.3 70.9 GO:0048268 clathrin coat assembly(GO:0048268)
2.2 6.5 GO:0010040 response to iron(II) ion(GO:0010040)
2.1 29.8 GO:0047484 regulation of response to osmotic stress(GO:0047484)
2.0 10.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.8 7.2 GO:0051866 general adaptation syndrome(GO:0051866)
1.8 5.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
1.7 23.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.7 5.0 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
1.6 8.1 GO:0003322 pancreatic A cell development(GO:0003322)
1.6 6.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.5 10.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.5 6.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
1.5 6.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
1.5 14.6 GO:0006600 creatine metabolic process(GO:0006600)
1.4 56.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
1.4 4.3 GO:0072092 ureteric bud invasion(GO:0072092)
1.4 12.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4 19.3 GO:0016081 synaptic vesicle docking(GO:0016081)
1.3 8.1 GO:0090131 mesenchyme migration(GO:0090131)
1.3 5.4 GO:0090076 relaxation of skeletal muscle(GO:0090076)
1.3 12.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.2 3.7 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
1.2 7.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
1.2 3.5 GO:0021571 rhombomere 5 development(GO:0021571)
1.1 5.7 GO:0000189 MAPK import into nucleus(GO:0000189)
1.1 4.5 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.1 4.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.1 10.9 GO:0042908 xenobiotic transport(GO:0042908)
1.0 3.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
1.0 3.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.0 7.0 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) midbrain-hindbrain boundary development(GO:0030917)
1.0 3.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.0 15.8 GO:0018298 protein-chromophore linkage(GO:0018298)
1.0 11.7 GO:0017121 phospholipid scrambling(GO:0017121)
1.0 1.9 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.9 7.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.9 5.5 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.9 19.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.9 4.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.9 24.8 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.9 5.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.8 15.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.8 20.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.7 3.0 GO:0070253 somatostatin secretion(GO:0070253)
0.7 2.9 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.7 8.4 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.7 10.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.7 2.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.7 20.2 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.6 5.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.6 1.9 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.6 8.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 4.3 GO:0023021 termination of signal transduction(GO:0023021)
0.6 4.9 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.6 1.8 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.6 2.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.6 12.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.6 2.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.6 7.9 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.5 4.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 4.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 12.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.5 5.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.5 4.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 1.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.5 0.9 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.5 1.4 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.4 2.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.4 13.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 1.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 6.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.4 9.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.4 4.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.4 3.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.4 7.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 3.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3 3.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 2.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 5.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 1.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.3 1.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.3 11.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 2.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 4.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 0.8 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.3 0.8 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 2.7 GO:0033227 dsRNA transport(GO:0033227)
0.2 3.7 GO:0045475 locomotor rhythm(GO:0045475)
0.2 4.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 3.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 4.0 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 1.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 1.6 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 1.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 1.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 5.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 7.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 0.9 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.2 2.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.2 2.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2 8.3 GO:0030199 collagen fibril organization(GO:0030199)
0.2 3.9 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 5.8 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.2 2.9 GO:0002467 germinal center formation(GO:0002467)
0.2 9.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 2.6 GO:0015671 oxygen transport(GO:0015671)
0.2 5.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 0.8 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.2 56.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.2 7.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.2 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 12.4 GO:0009060 aerobic respiration(GO:0009060)
0.2 2.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 6.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.2 12.2 GO:0070126 mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.2 5.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.2 0.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 5.8 GO:0030261 chromosome condensation(GO:0030261)
0.2 9.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 4.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 6.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 1.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.4 GO:0046541 saliva secretion(GO:0046541)
0.1 5.0 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.1 11.6 GO:0005977 glycogen metabolic process(GO:0005977)
0.1 6.6 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.1 4.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 4.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 3.3 GO:0010761 fibroblast migration(GO:0010761)
0.1 10.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 2.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 4.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 14.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 6.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 3.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 0.6 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.7 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1 1.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 3.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.1 GO:0097186 amelogenesis(GO:0097186)
0.1 1.1 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 0.6 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 3.8 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.7 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 1.9 GO:0030317 sperm motility(GO:0030317)
0.0 1.3 GO:0007586 digestion(GO:0007586)
0.0 0.8 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.5 GO:1903817 diaphragm development(GO:0060539) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.0 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 1.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 2.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 4.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 4.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 1.6 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 2.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.2 GO:0050890 cognition(GO:0050890)
0.0 3.0 GO:0006364 rRNA processing(GO:0006364)
0.0 1.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 120.0 GO:0097512 cardiac myofibril(GO:0097512)
5.2 15.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
4.5 13.6 GO:0071020 post-spliceosomal complex(GO:0071020)
3.2 9.7 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
2.8 8.3 GO:0005588 collagen type V trimer(GO:0005588)
2.2 10.8 GO:0001652 granular component(GO:0001652)
2.0 8.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.6 25.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.5 13.6 GO:0005955 calcineurin complex(GO:0005955)
1.4 8.3 GO:1990769 proximal neuron projection(GO:1990769)
1.3 5.3 GO:0070695 FHF complex(GO:0070695)
1.3 10.1 GO:0071204 U7 snRNP(GO:0005683) histone pre-mRNA 3'end processing complex(GO:0071204)
1.2 4.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
1.2 7.2 GO:0032280 symmetric synapse(GO:0032280)
1.2 35.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 9.1 GO:0070652 HAUS complex(GO:0070652)
1.0 4.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0 5.8 GO:0070545 PeBoW complex(GO:0070545)
0.9 7.4 GO:0045179 apical cortex(GO:0045179)
0.9 23.9 GO:0032982 myosin filament(GO:0032982)
0.9 14.9 GO:0033270 paranode region of axon(GO:0033270)
0.9 14.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.8 29.2 GO:0097542 ciliary tip(GO:0097542)
0.7 4.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.6 5.8 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.6 2.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6 38.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 7.5 GO:0017119 Golgi transport complex(GO:0017119)
0.5 50.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.4 63.1 GO:0044853 plasma membrane raft(GO:0044853)
0.4 4.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 5.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.4 5.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 9.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 4.9 GO:0030673 axolemma(GO:0030673)
0.4 14.6 GO:0042629 mast cell granule(GO:0042629)
0.4 7.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 30.7 GO:0008021 synaptic vesicle(GO:0008021)
0.4 67.5 GO:0030426 growth cone(GO:0030426)
0.3 26.2 GO:0042734 presynaptic membrane(GO:0042734)
0.3 8.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 2.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 12.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 8.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.3 15.4 GO:0031594 neuromuscular junction(GO:0031594)
0.3 2.2 GO:0043196 varicosity(GO:0043196)
0.3 2.3 GO:0045180 basal cortex(GO:0045180)
0.2 24.7 GO:0030658 transport vesicle membrane(GO:0030658)
0.2 9.0 GO:0043198 dendritic shaft(GO:0043198)
0.2 6.0 GO:0005921 gap junction(GO:0005921)
0.2 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.2 3.8 GO:0005859 muscle myosin complex(GO:0005859)
0.2 6.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 4.9 GO:0071565 nBAF complex(GO:0071565)
0.2 2.6 GO:0005833 hemoglobin complex(GO:0005833)
0.2 3.4 GO:0042599 lamellar body(GO:0042599)
0.2 5.4 GO:0014704 intercalated disc(GO:0014704)
0.2 3.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 4.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 17.1 GO:0030018 Z disc(GO:0030018)
0.2 35.9 GO:0045121 membrane raft(GO:0045121)
0.1 38.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 12.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 5.4 GO:0008305 integrin complex(GO:0008305)
0.1 10.1 GO:0043197 dendritic spine(GO:0043197)
0.1 3.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 5.0 GO:0016235 aggresome(GO:0016235)
0.1 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 7.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.5 GO:0001533 cornified envelope(GO:0001533)
0.1 4.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 7.1 GO:0005814 centriole(GO:0005814)
0.1 16.9 GO:0030424 axon(GO:0030424)
0.1 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 5.7 GO:0032587 ruffle membrane(GO:0032587)
0.1 6.5 GO:0034702 ion channel complex(GO:0034702)
0.1 20.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.8 GO:0005902 microvillus(GO:0005902)
0.1 7.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 7.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.7 GO:0044420 extracellular matrix component(GO:0044420)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 2.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.0 GO:0043209 myelin sheath(GO:0043209)
0.0 3.6 GO:0043235 receptor complex(GO:0043235)
0.0 1.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 2.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 4.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.8 GO:0035579 specific granule membrane(GO:0035579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 24.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
5.2 15.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
4.4 22.0 GO:0070097 delta-catenin binding(GO:0070097)
4.3 12.9 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
3.9 120.0 GO:0005212 structural constituent of eye lens(GO:0005212)
3.8 15.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.4 10.1 GO:0071209 U7 snRNA binding(GO:0071209)
3.3 43.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
3.3 36.1 GO:0008430 selenium binding(GO:0008430)
3.2 9.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
3.2 12.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
2.6 10.5 GO:0061714 folic acid receptor activity(GO:0061714)
2.6 20.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
2.5 14.9 GO:1903135 cupric ion binding(GO:1903135)
2.4 55.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
2.2 30.3 GO:0042043 neurexin family protein binding(GO:0042043)
2.0 20.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
2.0 6.1 GO:0032427 GBD domain binding(GO:0032427)
1.9 15.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.8 14.6 GO:0004111 creatine kinase activity(GO:0004111)
1.8 10.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.8 35.6 GO:0045504 dynein heavy chain binding(GO:0045504)
1.7 15.3 GO:0032051 clathrin light chain binding(GO:0032051)
1.7 23.7 GO:0031432 titin binding(GO:0031432)
1.7 5.0 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
1.6 4.9 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
1.5 11.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.4 15.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
1.4 10.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.3 7.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 4.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.2 4.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.1 41.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.1 11.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.1 13.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.0 5.0 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
1.0 20.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.9 6.4 GO:0001515 opioid peptide activity(GO:0001515)
0.9 7.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.9 11.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.8 10.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.8 19.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 5.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.7 2.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.7 19.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 12.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.7 22.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.6 6.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.6 18.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.6 17.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 3.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.6 4.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 2.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.5 8.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.5 7.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.5 4.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 11.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.5 1.9 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.5 3.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.5 2.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 5.8 GO:0048156 tau protein binding(GO:0048156)
0.4 4.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 1.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.4 7.4 GO:0043274 phospholipase binding(GO:0043274)
0.4 10.8 GO:0071949 FAD binding(GO:0071949)
0.4 3.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 5.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.4 11.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 10.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.4 5.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.4 5.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 1.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.4 4.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 2.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 16.9 GO:0070412 R-SMAD binding(GO:0070412)
0.3 5.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 4.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 12.8 GO:0030552 cAMP binding(GO:0030552)
0.3 7.1 GO:0042166 acetylcholine binding(GO:0042166)
0.3 7.7 GO:0016805 dipeptidase activity(GO:0016805)
0.3 8.3 GO:0043394 proteoglycan binding(GO:0043394)
0.3 1.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 5.0 GO:0031005 filamin binding(GO:0031005)
0.3 1.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 7.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 1.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.3 0.3 GO:0050436 microfibril binding(GO:0050436)
0.3 18.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 4.2 GO:0038191 neuropilin binding(GO:0038191)
0.3 0.8 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 10.2 GO:0050699 WW domain binding(GO:0050699)
0.2 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 6.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 6.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 7.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 4.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 18.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 8.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 3.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 6.2 GO:0005123 death receptor binding(GO:0005123)
0.2 2.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 2.9 GO:0016918 retinal binding(GO:0016918)
0.2 5.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.7 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 2.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 4.7 GO:0015248 sterol transporter activity(GO:0015248)
0.2 3.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.9 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 2.3 GO:0001948 glycoprotein binding(GO:0001948)
0.1 3.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 3.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 11.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 2.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 6.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 7.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 6.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 4.9 GO:0030507 spectrin binding(GO:0030507)
0.1 2.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 6.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 3.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 12.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 7.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 4.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 4.7 GO:0008083 growth factor activity(GO:0008083)
0.0 1.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 5.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 16.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 4.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 18.0 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 3.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 38.6 ST GAQ PATHWAY G alpha q Pathway
0.7 24.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.7 20.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 20.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.6 28.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.5 25.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 20.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 55.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 20.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.3 18.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 7.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 13.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 5.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 4.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 21.9 PID AP1 PATHWAY AP-1 transcription factor network
0.2 9.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 2.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 8.3 NABA COLLAGENS Genes encoding collagen proteins
0.2 13.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 4.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 5.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 21.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 8.1 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 6.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.1 PID FGF PATHWAY FGF signaling pathway
0.1 1.6 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 22.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.8 53.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED