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GNF SymAtlas + NCI-60 cancer cell lines, comparison of cancers vs non-cancers, human (Su, 2004; Ross, 2000)
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Results for TLX1_NFIC
Z-value: 0.60
Motif logo
Transcription factors associated with TLX1_NFIC
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TLX1
|
ENSG00000107807.8 | T cell leukemia homeobox 1 |
|
NFIC
|
ENSG00000141905.13 | nuclear factor I C |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIC | hg19_v2_chr19_+_3366547_3366619 | 0.45 | 2.9e-12 | Click! |
| TLX1 | hg19_v2_chr10_+_102891048_102891078 | 0.35 | 1.3e-07 | Click! |
Activity profile of TLX1_NFIC motif
Sorted Z-values of TLX1_NFIC motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_74728998 | 76.22 |
ENST00000359645.3
ENST00000397875.3 ENST00000397869.3 ENST00000578193.1 ENST00000578873.1 ENST00000397866.4 ENST00000528160.1 ENST00000527041.1 ENST00000526111.1 ENST00000397865.5 ENST00000382582.3 |
MBP
|
myelin basic protein |
| chr16_+_226658 | 70.91 |
ENST00000320868.5
ENST00000397797.1 |
HBA1
|
hemoglobin, alpha 1 |
| chr8_-_27468842 | 66.99 |
ENST00000523500.1
|
CLU
|
clusterin |
| chr11_-_111783919 | 62.47 |
ENST00000531198.1
ENST00000533879.1 |
CRYAB
|
crystallin, alpha B |
| chr11_-_111784005 | 53.52 |
ENST00000527899.1
|
CRYAB
|
crystallin, alpha B |
| chr3_-_58613323 | 52.84 |
ENST00000474531.1
ENST00000465970.1 |
FAM107A
|
family with sequence similarity 107, member A |
| chr9_+_139871948 | 52.40 |
ENST00000224167.2
ENST00000457950.1 ENST00000371625.3 ENST00000371623.3 |
PTGDS
|
prostaglandin D2 synthase 21kDa (brain) |
| chr8_-_27468945 | 52.25 |
ENST00000405140.3
|
CLU
|
clusterin |
| chr16_+_222846 | 49.53 |
ENST00000251595.6
ENST00000397806.1 |
HBA2
|
hemoglobin, alpha 2 |
| chr11_-_111781454 | 49.17 |
ENST00000533280.1
|
CRYAB
|
crystallin, alpha B |
| chrX_-_102319092 | 47.12 |
ENST00000372728.3
|
BEX1
|
brain expressed, X-linked 1 |
| chr8_-_27469196 | 46.57 |
ENST00000546343.1
ENST00000560566.1 |
CLU
|
clusterin |
| chrX_+_102631844 | 44.87 |
ENST00000372634.1
ENST00000299872.7 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chrX_+_102631248 | 41.29 |
ENST00000361298.4
ENST00000372645.3 ENST00000372635.1 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr14_+_73704201 | 37.80 |
ENST00000340738.5
ENST00000427855.1 ENST00000381166.3 |
PAPLN
|
papilin, proteoglycan-like sulfated glycoprotein |
| chr12_+_66218212 | 33.56 |
ENST00000393578.3
ENST00000425208.2 ENST00000536545.1 ENST00000354636.3 |
HMGA2
|
high mobility group AT-hook 2 |
| chr22_-_37213045 | 29.77 |
ENST00000406910.2
ENST00000417718.2 |
PVALB
|
parvalbumin |
| chr8_+_24772455 | 29.56 |
ENST00000433454.2
|
NEFM
|
neurofilament, medium polypeptide |
| chr8_-_42065187 | 29.28 |
ENST00000270189.6
ENST00000352041.3 ENST00000220809.4 |
PLAT
|
plasminogen activator, tissue |
| chr17_-_42992856 | 27.11 |
ENST00000588316.1
ENST00000435360.2 ENST00000586793.1 ENST00000588735.1 ENST00000588037.1 ENST00000592320.1 ENST00000253408.5 |
GFAP
|
glial fibrillary acidic protein |
| chr1_+_65775204 | 27.05 |
ENST00000371069.4
|
DNAJC6
|
DnaJ (Hsp40) homolog, subfamily C, member 6 |
| chr22_-_37213554 | 26.42 |
ENST00000443735.1
|
PVALB
|
parvalbumin |
| chr14_+_85996471 | 26.37 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr22_+_40390930 | 26.21 |
ENST00000333407.6
|
FAM83F
|
family with sequence similarity 83, member F |
| chr16_-_19896220 | 25.82 |
ENST00000562469.1
ENST00000300571.2 |
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chr10_+_106034884 | 24.93 |
ENST00000369707.2
ENST00000429569.2 |
GSTO2
|
glutathione S-transferase omega 2 |
| chr8_-_42065075 | 24.43 |
ENST00000429089.2
ENST00000519510.1 ENST00000429710.2 ENST00000524009.1 |
PLAT
|
plasminogen activator, tissue |
| chrX_-_13956737 | 24.42 |
ENST00000454189.2
|
GPM6B
|
glycoprotein M6B |
| chr13_+_113622757 | 23.82 |
ENST00000375604.2
|
MCF2L
|
MCF.2 cell line derived transforming sequence-like |
| chr8_-_80680078 | 23.74 |
ENST00000337919.5
ENST00000354724.3 |
HEY1
|
hes-related family bHLH transcription factor with YRPW motif 1 |
| chr5_-_73937244 | 22.32 |
ENST00000302351.4
ENST00000510316.1 ENST00000508331.1 |
ENC1
|
ectodermal-neural cortex 1 (with BTB domain) |
| chr12_-_56106060 | 22.12 |
ENST00000452168.2
|
ITGA7
|
integrin, alpha 7 |
| chr13_+_113622810 | 21.07 |
ENST00000397030.1
|
MCF2L
|
MCF.2 cell line derived transforming sequence-like |
| chr6_+_31949801 | 20.76 |
ENST00000428956.2
ENST00000498271.1 |
C4A
|
complement component 4A (Rodgers blood group) |
| chr21_-_28217721 | 19.27 |
ENST00000284984.3
|
ADAMTS1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| chr22_+_41763274 | 18.95 |
ENST00000406644.3
|
TEF
|
thyrotrophic embryonic factor |
| chr7_+_116165038 | 18.84 |
ENST00000393470.1
|
CAV1
|
caveolin 1, caveolae protein, 22kDa |
| chr6_+_31982539 | 18.39 |
ENST00000435363.2
ENST00000425700.2 |
C4B
|
complement component 4B (Chido blood group) |
| chr14_+_105939276 | 18.33 |
ENST00000483017.3
|
CRIP2
|
cysteine-rich protein 2 |
| chr3_+_14989186 | 17.94 |
ENST00000435454.1
ENST00000323373.6 |
NR2C2
|
nuclear receptor subfamily 2, group C, member 2 |
| chr2_-_217560248 | 17.26 |
ENST00000233813.4
|
IGFBP5
|
insulin-like growth factor binding protein 5 |
| chr9_+_124030338 | 16.60 |
ENST00000449773.1
ENST00000432226.1 ENST00000436847.1 ENST00000394353.2 ENST00000449733.1 ENST00000412819.1 ENST00000341272.2 ENST00000373808.2 |
GSN
|
gelsolin |
| chr2_+_102721023 | 15.21 |
ENST00000409589.1
ENST00000409329.1 |
IL1R1
|
interleukin 1 receptor, type I |
| chr6_+_29555683 | 14.82 |
ENST00000383640.2
|
OR2H2
|
olfactory receptor, family 2, subfamily H, member 2 |
| chr17_-_26903900 | 14.52 |
ENST00000395319.3
ENST00000581807.1 ENST00000584086.1 ENST00000395321.2 |
ALDOC
|
aldolase C, fructose-bisphosphate |
| chr6_-_46922659 | 14.13 |
ENST00000265417.7
|
GPR116
|
G protein-coupled receptor 116 |
| chr14_+_24867992 | 14.13 |
ENST00000382554.3
|
NYNRIN
|
NYN domain and retroviral integrase containing |
| chr1_+_110453109 | 13.83 |
ENST00000525659.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chrX_+_46937745 | 13.14 |
ENST00000397180.1
ENST00000457380.1 ENST00000352078.4 |
RGN
|
regucalcin |
| chr20_+_44034804 | 13.09 |
ENST00000357275.2
ENST00000372720.3 |
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| chr3_-_12200851 | 12.95 |
ENST00000287814.4
|
TIMP4
|
TIMP metallopeptidase inhibitor 4 |
| chr7_-_37024665 | 12.85 |
ENST00000396040.2
|
ELMO1
|
engulfment and cell motility 1 |
| chr2_-_238322770 | 12.78 |
ENST00000472056.1
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr6_+_123100620 | 12.76 |
ENST00000368444.3
|
FABP7
|
fatty acid binding protein 7, brain |
| chr2_-_238323007 | 12.60 |
ENST00000295550.4
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr17_+_38599693 | 12.37 |
ENST00000542955.1
ENST00000269593.4 |
IGFBP4
|
insulin-like growth factor binding protein 4 |
| chr14_-_50999190 | 12.32 |
ENST00000557390.1
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5 |
| chr2_-_238322800 | 12.29 |
ENST00000392004.3
ENST00000433762.1 ENST00000347401.3 ENST00000353578.4 ENST00000346358.4 ENST00000392003.2 |
COL6A3
|
collagen, type VI, alpha 3 |
| chr11_-_117186946 | 12.18 |
ENST00000313005.6
ENST00000528053.1 |
BACE1
|
beta-site APP-cleaving enzyme 1 |
| chr11_+_1244288 | 11.78 |
ENST00000529681.1
ENST00000447027.1 |
MUC5B
|
mucin 5B, oligomeric mucus/gel-forming |
| chr1_+_156096336 | 11.77 |
ENST00000504687.1
ENST00000473598.2 |
LMNA
|
lamin A/C |
| chr1_+_10271674 | 11.77 |
ENST00000377086.1
|
KIF1B
|
kinesin family member 1B |
| chr12_+_119616447 | 11.52 |
ENST00000281938.2
|
HSPB8
|
heat shock 22kDa protein 8 |
| chr14_+_85996507 | 11.31 |
ENST00000554746.1
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr9_-_79520989 | 11.17 |
ENST00000376713.3
ENST00000376718.3 ENST00000428286.1 |
PRUNE2
|
prune homolog 2 (Drosophila) |
| chr9_-_130616915 | 11.06 |
ENST00000344849.3
|
ENG
|
endoglin |
| chr12_+_13349650 | 11.01 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
| chr16_+_23765948 | 10.96 |
ENST00000300113.2
|
CHP2
|
calcineurin-like EF-hand protein 2 |
| chr8_-_145701718 | 10.78 |
ENST00000377317.4
|
FOXH1
|
forkhead box H1 |
| chr19_+_45312347 | 10.78 |
ENST00000270233.6
ENST00000591520.1 |
BCAM
|
basal cell adhesion molecule (Lutheran blood group) |
| chr12_+_57522258 | 10.76 |
ENST00000553277.1
ENST00000243077.3 |
LRP1
|
low density lipoprotein receptor-related protein 1 |
| chr20_+_34742650 | 10.73 |
ENST00000373945.1
ENST00000338074.2 |
EPB41L1
|
erythrocyte membrane protein band 4.1-like 1 |
| chr6_+_150920999 | 10.69 |
ENST00000367328.1
ENST00000367326.1 |
PLEKHG1
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| chr6_+_39760783 | 10.69 |
ENST00000398904.2
ENST00000538976.1 |
DAAM2
|
dishevelled associated activator of morphogenesis 2 |
| chr5_-_115872142 | 10.33 |
ENST00000510263.1
|
SEMA6A
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| chr5_+_150020214 | 10.30 |
ENST00000307662.4
|
SYNPO
|
synaptopodin |
| chr9_-_130617029 | 10.27 |
ENST00000373203.4
|
ENG
|
endoglin |
| chr1_-_95392635 | 9.93 |
ENST00000538964.1
ENST00000394202.4 ENST00000370206.4 |
CNN3
|
calponin 3, acidic |
| chr3_+_53880588 | 9.89 |
ENST00000288167.3
ENST00000494338.1 |
IL17RB
|
interleukin 17 receptor B |
| chr6_-_53013620 | 9.87 |
ENST00000259803.7
|
GCM1
|
glial cells missing homolog 1 (Drosophila) |
| chr1_+_110453462 | 9.63 |
ENST00000488198.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr1_+_220960033 | 9.54 |
ENST00000366910.5
|
MARC1
|
mitochondrial amidoxime reducing component 1 |
| chr9_-_23821842 | 9.51 |
ENST00000544538.1
|
ELAVL2
|
ELAV like neuron-specific RNA binding protein 2 |
| chrX_-_133119476 | 9.42 |
ENST00000543339.1
|
GPC3
|
glypican 3 |
| chr20_+_44034676 | 9.41 |
ENST00000372723.3
ENST00000372722.3 |
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| chrX_-_133119670 | 9.38 |
ENST00000394299.2
|
GPC3
|
glypican 3 |
| chr1_-_16344500 | 9.33 |
ENST00000406363.2
ENST00000411503.1 ENST00000545268.1 ENST00000487046.1 |
HSPB7
|
heat shock 27kDa protein family, member 7 (cardiovascular) |
| chr16_-_2264779 | 9.33 |
ENST00000333503.7
|
PGP
|
phosphoglycolate phosphatase |
| chr11_+_74862140 | 9.31 |
ENST00000525650.1
ENST00000454962.2 |
SLCO2B1
|
solute carrier organic anion transporter family, member 2B1 |
| chr1_-_2323140 | 9.25 |
ENST00000378531.3
ENST00000378529.3 |
MORN1
|
MORN repeat containing 1 |
| chr8_+_85097110 | 9.13 |
ENST00000517638.1
ENST00000522647.1 |
RALYL
|
RALY RNA binding protein-like |
| chr12_+_53491220 | 8.95 |
ENST00000548547.1
ENST00000301464.3 |
IGFBP6
|
insulin-like growth factor binding protein 6 |
| chr1_+_110453608 | 8.86 |
ENST00000369801.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr7_+_86273700 | 8.83 |
ENST00000546348.1
|
GRM3
|
glutamate receptor, metabotropic 3 |
| chr9_-_14180778 | 8.43 |
ENST00000380924.1
ENST00000543693.1 |
NFIB
|
nuclear factor I/B |
| chr19_-_36247910 | 8.41 |
ENST00000587965.1
ENST00000004982.3 |
HSPB6
|
heat shock protein, alpha-crystallin-related, B6 |
| chr5_+_92919043 | 8.41 |
ENST00000327111.3
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1 |
| chr9_-_13279589 | 8.40 |
ENST00000319217.7
|
MPDZ
|
multiple PDZ domain protein |
| chr8_-_13134045 | 8.40 |
ENST00000512044.2
|
DLC1
|
deleted in liver cancer 1 |
| chr22_-_46450024 | 8.27 |
ENST00000396008.2
ENST00000333761.1 |
C22orf26
|
chromosome 22 open reading frame 26 |
| chr7_+_86273952 | 8.27 |
ENST00000536043.1
|
GRM3
|
glutamate receptor, metabotropic 3 |
| chr9_-_13279563 | 8.25 |
ENST00000541718.1
|
MPDZ
|
multiple PDZ domain protein |
| chr8_-_18541603 | 8.23 |
ENST00000428502.2
|
PSD3
|
pleckstrin and Sec7 domain containing 3 |
| chr1_+_179262905 | 8.22 |
ENST00000539888.1
ENST00000540564.1 ENST00000535686.1 ENST00000367619.3 |
SOAT1
|
sterol O-acyltransferase 1 |
| chr1_+_110453203 | 8.18 |
ENST00000357302.4
ENST00000344188.5 ENST00000329608.6 |
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr10_+_17271266 | 8.04 |
ENST00000224237.5
|
VIM
|
vimentin |
| chr15_-_40213080 | 8.01 |
ENST00000561100.1
|
GPR176
|
G protein-coupled receptor 176 |
| chr19_+_58111241 | 7.88 |
ENST00000597700.1
ENST00000332854.6 ENST00000597864.1 |
ZNF530
|
zinc finger protein 530 |
| chr12_+_6644443 | 7.74 |
ENST00000396858.1
|
GAPDH
|
glyceraldehyde-3-phosphate dehydrogenase |
| chrX_-_133119895 | 7.73 |
ENST00000370818.3
|
GPC3
|
glypican 3 |
| chr5_-_111093406 | 7.73 |
ENST00000379671.3
|
NREP
|
neuronal regeneration related protein |
| chr19_+_10397621 | 7.71 |
ENST00000380770.3
|
ICAM4
|
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| chr20_+_19867150 | 7.57 |
ENST00000255006.6
|
RIN2
|
Ras and Rab interactor 2 |
| chr1_-_243418621 | 7.56 |
ENST00000366544.1
ENST00000366543.1 |
CEP170
|
centrosomal protein 170kDa |
| chr19_+_10397648 | 7.49 |
ENST00000340992.4
ENST00000393717.2 |
ICAM4
|
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| chr20_-_60942361 | 7.46 |
ENST00000252999.3
|
LAMA5
|
laminin, alpha 5 |
| chr21_+_46875424 | 7.46 |
ENST00000359759.4
|
COL18A1
|
collagen, type XVIII, alpha 1 |
| chr12_-_124457371 | 7.44 |
ENST00000238156.3
ENST00000545037.1 |
CCDC92
|
coiled-coil domain containing 92 |
| chr21_+_46875395 | 7.25 |
ENST00000355480.5
|
COL18A1
|
collagen, type XVIII, alpha 1 |
| chr7_+_22766766 | 7.21 |
ENST00000426291.1
ENST00000401651.1 ENST00000258743.5 ENST00000420258.2 ENST00000407492.1 ENST00000401630.3 ENST00000406575.1 |
IL6
|
interleukin 6 (interferon, beta 2) |
| chr18_-_52989217 | 7.12 |
ENST00000570287.2
|
TCF4
|
transcription factor 4 |
| chr6_-_30043539 | 7.07 |
ENST00000376751.3
ENST00000244360.6 |
RNF39
|
ring finger protein 39 |
| chr3_-_114866084 | 7.07 |
ENST00000357258.3
|
ZBTB20
|
zinc finger and BTB domain containing 20 |
| chr5_-_111092930 | 6.99 |
ENST00000257435.7
|
NREP
|
neuronal regeneration related protein |
| chr7_+_86274145 | 6.96 |
ENST00000439827.1
ENST00000394720.2 ENST00000421579.1 |
GRM3
|
glutamate receptor, metabotropic 3 |
| chr17_+_26684604 | 6.94 |
ENST00000292114.3
ENST00000509083.1 |
TMEM199
|
transmembrane protein 199 |
| chr8_-_82395461 | 6.87 |
ENST00000256104.4
|
FABP4
|
fatty acid binding protein 4, adipocyte |
| chr1_-_161168834 | 6.82 |
ENST00000367995.3
ENST00000367996.5 |
ADAMTS4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| chr11_+_61717336 | 6.81 |
ENST00000378042.3
|
BEST1
|
bestrophin 1 |
| chr4_+_158142750 | 6.79 |
ENST00000505888.1
ENST00000449365.1 |
GRIA2
|
glutamate receptor, ionotropic, AMPA 2 |
| chr11_+_61717279 | 6.79 |
ENST00000378043.4
|
BEST1
|
bestrophin 1 |
| chr8_+_133931648 | 6.77 |
ENST00000519178.1
ENST00000542445.1 |
TG
|
thyroglobulin |
| chr9_-_130487143 | 6.76 |
ENST00000419060.1
|
PTRH1
|
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) |
| chrX_+_2746818 | 6.71 |
ENST00000398806.3
|
GYG2
|
glycogenin 2 |
| chr11_+_27062502 | 6.68 |
ENST00000263182.3
|
BBOX1
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| chr12_+_50355647 | 6.66 |
ENST00000293599.6
|
AQP5
|
aquaporin 5 |
| chr19_+_11651942 | 6.60 |
ENST00000587087.1
|
CNN1
|
calponin 1, basic, smooth muscle |
| chr3_-_50340996 | 6.58 |
ENST00000266031.4
ENST00000395143.2 ENST00000457214.2 ENST00000447605.2 ENST00000418723.1 ENST00000395144.2 |
HYAL1
|
hyaluronoglucosaminidase 1 |
| chr14_-_76447494 | 6.44 |
ENST00000238682.3
|
TGFB3
|
transforming growth factor, beta 3 |
| chr19_+_4304632 | 6.41 |
ENST00000597590.1
|
FSD1
|
fibronectin type III and SPRY domain containing 1 |
| chr19_-_15087839 | 6.29 |
ENST00000600144.1
|
SLC1A6
|
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| chr15_-_65503801 | 6.21 |
ENST00000261883.4
|
CILP
|
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| chr8_-_21988558 | 6.20 |
ENST00000312841.8
|
HR
|
hair growth associated |
| chr9_+_470288 | 5.92 |
ENST00000382303.1
|
KANK1
|
KN motif and ankyrin repeat domains 1 |
| chr7_+_143078652 | 5.88 |
ENST00000354434.4
ENST00000449423.2 |
ZYX
|
zyxin |
| chr19_+_4007644 | 5.85 |
ENST00000262971.2
|
PIAS4
|
protein inhibitor of activated STAT, 4 |
| chr19_+_50380682 | 5.85 |
ENST00000221543.5
|
TBC1D17
|
TBC1 domain family, member 17 |
| chr17_-_34329084 | 5.82 |
ENST00000354059.4
ENST00000536149.1 |
CCL15
CCL14
|
chemokine (C-C motif) ligand 15 chemokine (C-C motif) ligand 14 |
| chr2_+_66662690 | 5.80 |
ENST00000488550.1
|
MEIS1
|
Meis homeobox 1 |
| chr3_+_9791731 | 5.75 |
ENST00000449570.2
ENST00000302008.8 ENST00000383826.5 |
OGG1
|
8-oxoguanine DNA glycosylase |
| chr16_-_20367584 | 5.69 |
ENST00000570689.1
|
UMOD
|
uromodulin |
| chr12_+_109273806 | 5.63 |
ENST00000228476.3
ENST00000547768.1 |
DAO
|
D-amino-acid oxidase |
| chr1_-_32169761 | 5.60 |
ENST00000271069.6
|
COL16A1
|
collagen, type XVI, alpha 1 |
| chr1_-_151345159 | 5.59 |
ENST00000458566.1
ENST00000447402.3 ENST00000426705.2 ENST00000435071.1 ENST00000368868.5 |
SELENBP1
|
selenium binding protein 1 |
| chr5_-_114880533 | 5.50 |
ENST00000274457.3
|
FEM1C
|
fem-1 homolog c (C. elegans) |
| chr3_-_10547333 | 5.49 |
ENST00000383800.4
|
ATP2B2
|
ATPase, Ca++ transporting, plasma membrane 2 |
| chr11_-_62457371 | 5.48 |
ENST00000317449.4
|
LRRN4CL
|
LRRN4 C-terminal like |
| chr1_-_32169920 | 5.47 |
ENST00000373672.3
ENST00000373668.3 |
COL16A1
|
collagen, type XVI, alpha 1 |
| chr17_+_48503603 | 5.43 |
ENST00000502667.1
|
ACSF2
|
acyl-CoA synthetase family member 2 |
| chrX_+_2746850 | 5.42 |
ENST00000381163.3
ENST00000338623.5 ENST00000542787.1 |
GYG2
|
glycogenin 2 |
| chr8_+_98881268 | 5.36 |
ENST00000254898.5
ENST00000524308.1 ENST00000522025.2 |
MATN2
|
matrilin 2 |
| chr15_-_93199069 | 5.35 |
ENST00000327355.5
|
FAM174B
|
family with sequence similarity 174, member B |
| chr17_+_27369918 | 5.34 |
ENST00000323372.4
|
PIPOX
|
pipecolic acid oxidase |
| chr19_+_496454 | 5.32 |
ENST00000346144.4
ENST00000215637.3 ENST00000382683.4 |
MADCAM1
|
mucosal vascular addressin cell adhesion molecule 1 |
| chr8_+_120428546 | 5.30 |
ENST00000259526.3
|
NOV
|
nephroblastoma overexpressed |
| chr15_-_77363375 | 5.26 |
ENST00000559494.1
|
TSPAN3
|
tetraspanin 3 |
| chr2_+_66662510 | 5.25 |
ENST00000272369.9
ENST00000407092.2 |
MEIS1
|
Meis homeobox 1 |
| chr4_+_144303093 | 5.21 |
ENST00000505913.1
|
GAB1
|
GRB2-associated binding protein 1 |
| chr22_+_26565440 | 5.14 |
ENST00000404234.3
ENST00000529632.2 ENST00000360929.3 ENST00000248933.6 ENST00000343706.4 |
SEZ6L
|
seizure related 6 homolog (mouse)-like |
| chr10_+_88718314 | 5.14 |
ENST00000348795.4
|
SNCG
|
synuclein, gamma (breast cancer-specific protein 1) |
| chr7_+_75931861 | 5.07 |
ENST00000248553.6
|
HSPB1
|
heat shock 27kDa protein 1 |
| chr19_+_17326521 | 5.07 |
ENST00000593597.1
|
USE1
|
unconventional SNARE in the ER 1 homolog (S. cerevisiae) |
| chr19_+_42788172 | 5.03 |
ENST00000160740.3
|
CIC
|
capicua transcriptional repressor |
| chr8_+_22022653 | 5.03 |
ENST00000354870.5
ENST00000397816.3 ENST00000306349.8 |
BMP1
|
bone morphogenetic protein 1 |
| chr7_-_45128472 | 4.85 |
ENST00000490531.2
|
NACAD
|
NAC alpha domain containing |
| chr10_+_124320156 | 4.82 |
ENST00000338354.3
ENST00000344338.3 ENST00000330163.4 ENST00000368909.3 ENST00000368955.3 ENST00000368956.2 |
DMBT1
|
deleted in malignant brain tumors 1 |
| chr7_+_128470431 | 4.81 |
ENST00000325888.8
ENST00000346177.6 |
FLNC
|
filamin C, gamma |
| chr19_-_33716750 | 4.81 |
ENST00000253188.4
|
SLC7A10
|
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
| chr11_+_61717535 | 4.76 |
ENST00000534553.1
ENST00000301774.9 |
BEST1
|
bestrophin 1 |
| chr17_+_48503519 | 4.74 |
ENST00000300441.4
ENST00000541920.1 ENST00000506582.1 ENST00000504392.1 ENST00000427954.2 |
ACSF2
|
acyl-CoA synthetase family member 2 |
| chr1_+_202995611 | 4.74 |
ENST00000367240.2
|
PPFIA4
|
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| chr9_-_77567743 | 4.67 |
ENST00000376854.5
|
C9orf40
|
chromosome 9 open reading frame 40 |
| chr5_+_113697983 | 4.64 |
ENST00000264773.3
|
KCNN2
|
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 |
| chr22_+_17082732 | 4.59 |
ENST00000558085.2
ENST00000592918.1 ENST00000400593.2 ENST00000592107.1 ENST00000426585.1 ENST00000591299.1 |
TPTEP1
|
transmembrane phosphatase with tensin homology pseudogene 1 |
| chr8_+_38243821 | 4.56 |
ENST00000519476.2
|
LETM2
|
leucine zipper-EF-hand containing transmembrane protein 2 |
| chr11_+_74862032 | 4.53 |
ENST00000289575.5
ENST00000341411.4 |
SLCO2B1
|
solute carrier organic anion transporter family, member 2B1 |
| chr1_-_160040038 | 4.50 |
ENST00000368089.3
|
KCNJ10
|
potassium inwardly-rectifying channel, subfamily J, member 10 |
| chr6_-_39197226 | 4.45 |
ENST00000359534.3
|
KCNK5
|
potassium channel, subfamily K, member 5 |
| chr18_+_33877654 | 4.45 |
ENST00000257209.4
ENST00000445677.1 ENST00000590592.1 ENST00000359247.4 |
FHOD3
|
formin homology 2 domain containing 3 |
| chr15_+_75105057 | 4.44 |
ENST00000309664.5
ENST00000562810.1 |
LMAN1L
|
lectin, mannose-binding, 1 like |
| chr9_+_27109133 | 4.31 |
ENST00000519097.1
ENST00000380036.4 |
TEK
|
TEK tyrosine kinase, endothelial |
| chr4_-_110723134 | 4.31 |
ENST00000510800.1
ENST00000512148.1 |
CFI
|
complement factor I |
| chr18_-_52989525 | 4.25 |
ENST00000457482.3
|
TCF4
|
transcription factor 4 |
| chr13_-_96705624 | 4.23 |
ENST00000376747.3
ENST00000376712.4 ENST00000397618.3 ENST00000376714.3 |
UGGT2
|
UDP-glucose glycoprotein glucosyltransferase 2 |
| chr6_+_28317685 | 4.22 |
ENST00000252211.2
ENST00000341464.5 ENST00000377255.3 |
ZKSCAN3
|
zinc finger with KRAB and SCAN domains 3 |
| chr10_+_124320195 | 4.22 |
ENST00000359586.6
|
DMBT1
|
deleted in malignant brain tumors 1 |
| chr15_-_77363441 | 4.17 |
ENST00000346495.2
ENST00000424443.3 ENST00000561277.1 |
TSPAN3
|
tetraspanin 3 |
| chr5_+_140855495 | 4.11 |
ENST00000308177.3
|
PCDHGC3
|
protocadherin gamma subfamily C, 3 |
| chr1_+_203595689 | 4.09 |
ENST00000357681.5
|
ATP2B4
|
ATPase, Ca++ transporting, plasma membrane 4 |
| chr19_-_42927251 | 4.02 |
ENST00000597001.1
|
LIPE
|
lipase, hormone-sensitive |
Network of associatons between targets according to the STRING database.
First level regulatory network of TLX1_NFIC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 27.6 | 165.8 | GO:0061518 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 15.2 | 76.2 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 9.9 | 29.6 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 9.2 | 165.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 8.9 | 44.4 | GO:1903974 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 7.9 | 23.8 | GO:0031049 | mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685) |
| 7.1 | 21.3 | GO:0001300 | chronological cell aging(GO:0001300) |
| 6.6 | 26.5 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 6.3 | 37.7 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 6.3 | 18.8 | GO:1900085 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 5.9 | 23.7 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 5.8 | 17.3 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 5.1 | 15.2 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 4.7 | 70.9 | GO:0015671 | oxygen transport(GO:0015671) |
| 4.5 | 22.3 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 4.4 | 13.1 | GO:0019853 | L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 3.9 | 11.8 | GO:1904647 | response to rotenone(GO:1904647) |
| 3.6 | 7.2 | GO:2000364 | regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366) |
| 3.6 | 10.8 | GO:2000824 | negative regulation of androgen receptor activity(GO:2000824) |
| 3.6 | 10.8 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 3.6 | 24.9 | GO:0009407 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 3.3 | 16.6 | GO:1903906 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 3.3 | 9.9 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
| 3.1 | 12.4 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 3.0 | 39.2 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 3.0 | 27.1 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 3.0 | 53.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 2.9 | 5.8 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 2.7 | 5.3 | GO:1990523 | bone regeneration(GO:1990523) |
| 2.6 | 7.7 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 2.4 | 24.4 | GO:0051612 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 2.4 | 4.8 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 2.3 | 6.9 | GO:1903248 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 2.2 | 6.6 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 2.2 | 6.5 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 2.1 | 8.2 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 2.0 | 53.7 | GO:0031639 | plasminogen activation(GO:0031639) |
| 2.0 | 5.9 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.9 | 27.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 1.9 | 11.5 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 1.9 | 5.6 | GO:0009080 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) |
| 1.8 | 9.0 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 1.8 | 5.3 | GO:0046440 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 1.7 | 8.5 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 1.6 | 6.4 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) frontal suture morphogenesis(GO:0060364) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075) |
| 1.6 | 24.1 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 1.5 | 25.8 | GO:0010935 | regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) |
| 1.5 | 17.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 1.4 | 9.9 | GO:0097396 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 1.4 | 18.4 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 1.4 | 4.2 | GO:0097359 | UDP-glucosylation(GO:0097359) |
| 1.4 | 12.6 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 1.4 | 19.3 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 1.4 | 9.5 | GO:0042126 | nitrate metabolic process(GO:0042126) |
| 1.3 | 6.7 | GO:0015669 | gas transport(GO:0015669) |
| 1.3 | 3.9 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
| 1.3 | 5.1 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 1.3 | 8.8 | GO:0045007 | depurination(GO:0045007) |
| 1.2 | 8.4 | GO:2000795 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 1.2 | 3.5 | GO:0021650 | vestibulocochlear nerve formation(GO:0021650) |
| 1.2 | 14.1 | GO:0015074 | DNA integration(GO:0015074) |
| 1.1 | 5.7 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 1.1 | 3.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 1.1 | 10.6 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 1.0 | 4.0 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 1.0 | 6.9 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 1.0 | 5.9 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.9 | 10.3 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.9 | 10.3 | GO:0099563 | modification of synaptic structure(GO:0099563) |
| 0.8 | 6.8 | GO:0015705 | iodide transport(GO:0015705) |
| 0.8 | 14.5 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.8 | 9.5 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
| 0.8 | 2.3 | GO:1904640 | response to methionine(GO:1904640) |
| 0.8 | 3.8 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.7 | 4.5 | GO:1990123 | L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123) |
| 0.7 | 12.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.7 | 2.1 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.7 | 2.1 | GO:0033386 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.7 | 11.1 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.7 | 3.4 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.7 | 2.0 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.6 | 1.9 | GO:0055073 | cadmium ion homeostasis(GO:0055073) |
| 0.6 | 4.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.6 | 8.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.6 | 4.6 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.6 | 11.0 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 4.4 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.5 | 5.3 | GO:0060020 | Bergmann glial cell differentiation(GO:0060020) |
| 0.5 | 4.2 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
| 0.5 | 12.1 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.5 | 9.3 | GO:0035966 | response to topologically incorrect protein(GO:0035966) |
| 0.5 | 10.2 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.5 | 5.5 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.5 | 2.0 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.5 | 37.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.5 | 9.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.5 | 2.3 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.4 | 0.9 | GO:1901300 | positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) |
| 0.4 | 1.3 | GO:2000523 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.4 | 10.1 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.4 | 1.7 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.4 | 6.9 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.4 | 15.2 | GO:0030198 | extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062) |
| 0.4 | 11.0 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.4 | 8.2 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.4 | 1.6 | GO:0090678 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.4 | 2.8 | GO:0048241 | epinephrine transport(GO:0048241) |
| 0.4 | 28.4 | GO:0034113 | heterotypic cell-cell adhesion(GO:0034113) |
| 0.4 | 11.1 | GO:0033622 | integrin activation(GO:0033622) |
| 0.4 | 6.6 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.4 | 12.2 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.4 | 10.4 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.4 | 1.8 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.3 | 10.8 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.3 | 1.7 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.3 | 14.8 | GO:0007618 | mating(GO:0007618) |
| 0.3 | 2.7 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.3 | 2.7 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.3 | 3.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.3 | 13.4 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.3 | 2.2 | GO:0010454 | negative regulation of cell fate commitment(GO:0010454) |
| 0.3 | 2.4 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.3 | 3.3 | GO:0051873 | killing by host of symbiont cells(GO:0051873) |
| 0.3 | 5.1 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.3 | 8.4 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.3 | 4.4 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.3 | 6.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.3 | 1.2 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.3 | 4.4 | GO:0071850 | mitotic spindle midzone assembly(GO:0051256) mitotic cell cycle arrest(GO:0071850) |
| 0.3 | 0.8 | GO:0072092 | olfactory bulb mitral cell layer development(GO:0061034) ureteric bud invasion(GO:0072092) |
| 0.3 | 1.7 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
| 0.3 | 10.7 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.3 | 12.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.3 | 5.2 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.3 | 1.0 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.3 | 8.3 | GO:0043030 | regulation of macrophage activation(GO:0043030) |
| 0.2 | 0.7 | GO:0019605 | benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605) |
| 0.2 | 2.7 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.2 | 0.9 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.2 | 8.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.2 | 5.1 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.2 | 8.0 | GO:0048512 | circadian behavior(GO:0048512) |
| 0.2 | 0.6 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.2 | 3.5 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.2 | 1.6 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.2 | 0.4 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.2 | 2.0 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.2 | 2.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.2 | 4.2 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.2 | 6.8 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.2 | 3.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.2 | 7.1 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.2 | 5.8 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.2 | 0.5 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.2 | 54.5 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.2 | 1.5 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
| 0.2 | 4.8 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.1 | 1.6 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.1 | 38.2 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.1 | 0.4 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.1 | 3.6 | GO:0035272 | exocrine system development(GO:0035272) |
| 0.1 | 5.4 | GO:0031102 | neuron projection regeneration(GO:0031102) |
| 0.1 | 4.1 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 3.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 0.8 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.1 | 10.7 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.1 | 2.5 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.1 | 1.1 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.1 | 2.8 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.1 | 4.7 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.1 | 23.5 | GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091) |
| 0.1 | 2.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 3.1 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 2.9 | GO:0050727 | regulation of inflammatory response(GO:0050727) |
| 0.1 | 5.8 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 8.7 | GO:0030449 | regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257) |
| 0.1 | 30.2 | GO:0001558 | regulation of cell growth(GO:0001558) |
| 0.1 | 1.3 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.1 | GO:0034163 | regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) |
| 0.1 | 3.7 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.1 | 3.4 | GO:0030282 | bone mineralization(GO:0030282) |
| 0.1 | 13.4 | GO:0048511 | rhythmic process(GO:0048511) |
| 0.1 | 1.1 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.1 | 4.1 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.1 | 0.3 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.5 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.0 | 1.9 | GO:0006875 | cellular metal ion homeostasis(GO:0006875) |
| 0.0 | 0.4 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
| 0.0 | 6.7 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.0 | 2.5 | GO:0070126 | mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126) |
| 0.0 | 1.1 | GO:0001764 | neuron migration(GO:0001764) |
| 0.0 | 2.3 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 2.0 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 0.7 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.2 | GO:1901748 | leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.0 | 2.4 | GO:0015031 | protein transport(GO:0015031) |
| 0.0 | 0.1 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 17.7 | 70.9 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 12.2 | 195.4 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 10.9 | 76.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 10.3 | 165.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 7.4 | 44.4 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 7.1 | 21.3 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 2.7 | 37.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 2.6 | 26.2 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 1.9 | 7.5 | GO:0043260 | laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 1.8 | 10.8 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 1.4 | 5.8 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 1.4 | 11.1 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 1.4 | 6.8 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 1.3 | 18.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 1.3 | 23.8 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 1.3 | 6.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 1.2 | 22.3 | GO:0031012 | extracellular matrix(GO:0031012) |
| 1.1 | 16.6 | GO:0030478 | actin cap(GO:0030478) |
| 1.1 | 7.7 | GO:0097452 | GAIT complex(GO:0097452) |
| 1.1 | 12.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.9 | 8.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.8 | 16.7 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.8 | 26.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.7 | 8.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.7 | 9.0 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.7 | 4.9 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.6 | 4.4 | GO:0060091 | kinocilium(GO:0060091) |
| 0.6 | 1.7 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.6 | 56.2 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.5 | 6.9 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.5 | 2.6 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.5 | 41.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.4 | 19.2 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.4 | 3.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.4 | 3.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.3 | 1.0 | GO:0097183 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.3 | 15.5 | GO:0008305 | integrin complex(GO:0008305) |
| 0.3 | 22.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.3 | 34.8 | GO:0005604 | basement membrane(GO:0005604) |
| 0.3 | 34.4 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 24.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.3 | 22.5 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.3 | 6.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.3 | 4.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.3 | 19.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.2 | 6.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 14.7 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.2 | 12.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.2 | 3.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.2 | 4.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.2 | 6.6 | GO:0098793 | presynapse(GO:0098793) |
| 0.2 | 14.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.2 | 11.0 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 5.3 | GO:0005921 | gap junction(GO:0005921) |
| 0.2 | 18.4 | GO:0044216 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.2 | 19.1 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 8.6 | GO:0016235 | aggresome(GO:0016235) |
| 0.2 | 3.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 43.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.2 | 2.4 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.2 | 6.3 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.2 | 16.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.2 | 22.5 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.2 | 2.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.7 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.2 | 11.0 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 29.0 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 10.8 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 51.7 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.1 | 19.8 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 11.6 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 47.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 2.6 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 18.4 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.1 | 0.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 2.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 3.6 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 5.8 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 9.1 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 1.9 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.9 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 2.5 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.8 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 5.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 1.3 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 7.1 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 5.8 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 1.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.8 | GO:0042383 | sarcolemma(GO:0042383) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.1 | 52.4 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 8.3 | 166.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 8.3 | 24.9 | GO:0016672 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 7.9 | 23.8 | GO:0035501 | MH1 domain binding(GO:0035501) |
| 7.4 | 44.4 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 6.6 | 26.5 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 6.4 | 76.2 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 6.3 | 18.8 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 5.9 | 23.7 | GO:0035939 | microsatellite binding(GO:0035939) |
| 5.8 | 178.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 5.5 | 70.9 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 4.8 | 24.1 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 4.1 | 12.2 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 3.8 | 15.2 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 3.5 | 38.6 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 3.1 | 9.3 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 3.0 | 12.1 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 2.8 | 27.8 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 2.7 | 10.8 | GO:0042954 | apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954) |
| 2.6 | 20.8 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 2.4 | 9.5 | GO:0008940 | nitrate reductase activity(GO:0008940) |
| 2.4 | 37.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 2.3 | 6.9 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 2.3 | 6.8 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 2.2 | 6.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 1.9 | 7.7 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 1.8 | 5.3 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 1.7 | 5.2 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
| 1.7 | 5.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 1.7 | 6.7 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 1.4 | 9.9 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 1.4 | 4.2 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
| 1.4 | 16.6 | GO:0045159 | myosin II binding(GO:0045159) |
| 1.3 | 4.0 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 1.3 | 14.5 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 1.3 | 6.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 1.2 | 18.4 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 1.2 | 5.8 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 1.1 | 6.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 1.1 | 8.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 1.0 | 3.0 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 1.0 | 10.9 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.9 | 4.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.9 | 6.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.9 | 5.3 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.9 | 6.2 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.9 | 11.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.8 | 18.0 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.7 | 4.5 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.7 | 5.8 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.7 | 76.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.7 | 2.8 | GO:1901375 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 0.7 | 41.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.7 | 18.4 | GO:0001848 | complement binding(GO:0001848) |
| 0.6 | 1.9 | GO:0051139 | metal ion:proton antiporter activity(GO:0051139) |
| 0.6 | 1.8 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.6 | 6.8 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.6 | 10.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.5 | 2.1 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.5 | 5.6 | GO:0008430 | selenium binding(GO:0008430) |
| 0.5 | 1.5 | GO:0097259 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.5 | 3.4 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.5 | 9.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.5 | 10.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.5 | 7.3 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.5 | 6.9 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.4 | 10.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.4 | 4.8 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.4 | 2.1 | GO:0004337 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.4 | 52.7 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.4 | 2.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.4 | 3.5 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.4 | 9.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.4 | 9.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.3 | 3.5 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.3 | 1.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.3 | 2.0 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.3 | 20.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.3 | 8.2 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.3 | 10.8 | GO:0043236 | laminin binding(GO:0043236) |
| 0.3 | 6.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.3 | 3.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.3 | 53.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.3 | 8.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.3 | 5.7 | GO:0019864 | IgG binding(GO:0019864) |
| 0.3 | 5.5 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.3 | 28.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.3 | 26.2 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.3 | 10.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.3 | 5.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.3 | 11.8 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.2 | 1.7 | GO:0001093 | TFIIB-class transcription factor binding(GO:0001093) |
| 0.2 | 0.4 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) |
| 0.2 | 2.7 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.2 | 0.9 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 10.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 3.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.2 | 21.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 5.2 | GO:0016303 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) |
| 0.2 | 4.0 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.2 | 4.2 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.2 | 0.5 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.2 | 2.0 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.2 | 7.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.2 | 1.6 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 3.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 1.5 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.1 | 3.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.8 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 14.8 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 14.7 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.1 | 2.6 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 14.1 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 1.1 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 7.4 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 50.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.1 | 13.1 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.1 | 0.1 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.1 | 1.6 | GO:0005372 | water transmembrane transporter activity(GO:0005372) |
| 0.1 | 6.7 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.1 | 1.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 1.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 10.7 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 5.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 1.2 | GO:0030553 | cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.4 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.0 | 1.7 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 3.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 4.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 5.4 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 1.1 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.6 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.0 | 0.2 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.0 | 1.2 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 7.2 | ST STAT3 PATHWAY | STAT3 Pathway |
| 1.8 | 93.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 1.4 | 70.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 1.3 | 43.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.1 | 46.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 1.1 | 156.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.9 | 107.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.8 | 62.9 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.8 | 38.2 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.7 | 20.0 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.7 | 8.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.7 | 15.5 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.7 | 5.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.6 | 5.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.5 | 13.7 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.5 | 12.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.4 | 11.1 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.4 | 60.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.3 | 17.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.3 | 56.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 5.8 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 3.3 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.3 | 10.7 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.3 | 8.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.2 | 2.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.2 | 10.1 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.2 | 5.8 | ST ADRENERGIC | Adrenergic Pathway |
| 0.2 | 1.7 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.2 | 3.7 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.2 | 7.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.2 | 6.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 5.0 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.2 | 10.1 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 4.3 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 31.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 11.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 5.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.2 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.1 | 1.3 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 2.8 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 3.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.8 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 2.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.1 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.3 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.3 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 38.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.3 | 24.1 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 1.2 | 31.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 1.2 | 179.1 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 1.0 | 29.7 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 1.0 | 5.1 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 1.0 | 81.4 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.8 | 50.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.8 | 26.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.7 | 2.8 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.7 | 21.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.6 | 11.8 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.6 | 11.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.5 | 6.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.5 | 25.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.5 | 10.3 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.5 | 28.8 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.5 | 5.2 | REACTOME GAB1 SIGNALOSOME | Genes involved in GAB1 signalosome |
| 0.4 | 8.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.4 | 23.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.4 | 10.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.4 | 8.4 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.4 | 5.8 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.4 | 17.5 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.3 | 6.6 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.3 | 9.3 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.3 | 12.9 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.3 | 5.2 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.3 | 4.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.3 | 17.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.3 | 2.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.2 | 4.2 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 3.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.2 | 26.3 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.2 | 11.4 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 3.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 8.5 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.2 | 18.8 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 7.6 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.2 | 5.1 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 12.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 4.5 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 8.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 1.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 1.6 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 2.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 2.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 3.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.7 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 2.0 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.3 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 2.1 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 15.5 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 0.8 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 1.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 1.2 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.5 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |